CN113311181A - Reading device for full-automatic chemiluminescence immunoassay analyzer and scheduling method thereof - Google Patents

Reading device for full-automatic chemiluminescence immunoassay analyzer and scheduling method thereof Download PDF

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Publication number
CN113311181A
CN113311181A CN202110766159.4A CN202110766159A CN113311181A CN 113311181 A CN113311181 A CN 113311181A CN 202110766159 A CN202110766159 A CN 202110766159A CN 113311181 A CN113311181 A CN 113311181A
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Prior art keywords
cup
reading
plate
direction moving
seat
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Inventor
张燕
孙启鹏
董飒英
王峰
丛日波
苏桂香
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Yantai Addcare Bio Tech Ltd
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Yantai Addcare Bio Tech Ltd
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Priority to CN202110766159.4A priority Critical patent/CN113311181A/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

The invention relates to a reading device for a full-automatic chemiluminescence immunoassay analyzer and a scheduling method thereof, belonging to the technical field of medical detection equipment, wherein the reading device comprises a bottom plate, an optical reading module, an X-direction moving motor, a Z-direction moving screw rod motor and an exciting liquid fixing seat; the bottom plate is provided with a reading plate and a front baffle, one side of the reading plate is provided with an optical reading module, the light screen is connected with the middle part of the bottom plate through a telescopic spring, and the light screen and the cup seat are both positioned between the reading plate and the front baffle; an X-direction moving motor is arranged at one end of the bottom plate, a motor shaft of the X-direction moving motor is provided with a belt wheel, the belt wheel is connected with a bearing wheel through a synchronous belt, and a cup holder is fixed on the synchronous belt; the Z-direction moving screw rod motor drives the waste liquid needle assembly through the nut seat, the exciting liquid fixing seat is provided with a heat insulation assembly, and the exciting liquid needle is arranged in the heat insulation assembly. The reading device has the advantages of simple structure, high efficiency, stable reading, small deviation of a test result and high accuracy.

Description

Reading device for full-automatic chemiluminescence immunoassay analyzer and scheduling method thereof
Technical Field
The invention relates to a reading device for a full-automatic chemiluminescence immunoassay analyzer and a scheduling method thereof, belonging to the technical field of medical detection equipment.
Background
The chemiluminescence immunoassay analyzer is a medical detection instrument for immunoassay by detecting serum, and can be used for detection and analysis of various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins, drugs and the like by combining chemiluminescence measurement technology with high sensitivity and high specificity immunoreaction.
Chemiluminescence immunoassay is carried out by directly labeling an antigen or an antibody with a chemiluminescence reagent. And adding an exciting liquid into the reaction sample, and measuring the luminous value of the sample. The excitation liquid is placed in a working environment, the temperature of the excitation liquid changes along with the temperature of the environment, so that the excitation effect of the excitation liquid during the excitation luminescence reaction changes, and the test result is unstable.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides the reading device for the full-automatic chemiluminescence immunoassay analyzer and the scheduling method thereof, which can accurately control the temperature of the excitation liquid and improve the excitation effect of the excitation liquid, thereby enabling the test result to be more stable.
The technical scheme for solving the technical problems is as follows: a reading device for a full-automatic chemiluminescence immunoassay analyzer comprises a supporting rod, a bottom plate, an optical reading module, an X-direction moving motor, a Z-direction moving screw rod motor, an exciting liquid fixing seat, a shading plate, a cup seat and a waste liquid needle assembly;
the upper end of the supporting rod is provided with the bottom plate, the bottom plate is provided with the X-direction moving motor and the Z-direction moving screw rod motor, the upper end of the bottom plate is provided with a reading plate and a front baffle plate, one side of the reading plate is provided with the optical reading module, the other side of the reading plate is provided with an X-direction guide rail, the side surface of the shading plate is in sliding connection with the X-direction guide rail through a sliding block, the shading plate is connected with the middle part of the bottom plate through a telescopic spring, and the shading plate and the cup holder are both positioned between the reading plate and the front baffle plate;
the X-direction moving motor is mounted at one end of the bottom plate, a belt wheel is mounted on a motor shaft of the X-direction moving motor, a bearing wheel is mounted at the other end of the bottom plate, the belt wheel is connected with the bearing wheel through a synchronous belt, the cup holder is fixedly mounted on the synchronous belt, the side surface of the cup holder is in sliding connection with the X-direction guide rail through a sliding block, and a reaction cup containing a sample is placed in the cup holder;
the Z-direction moving screw rod motor is driven to drive the waste liquid needle assembly through the nut seat, the end parts of the reading plate and the front baffle are provided with side baffles, the upper ends of the side baffles are provided with excitation liquid fixing seats, the excitation liquid fixing seats are provided with heat insulation assemblies, and excitation liquid needles are arranged inside the heat insulation assemblies.
On the basis of the technical scheme, the invention can be further improved as follows:
further, the subassembly that keeps warm include the heat preservation needle fixing base, heat preservation needle fixing base internally mounted has the heating piece, heating piece mid-mounting has the heating rod, temperature sensor is installed at the top of heating piece, temperature sensor with the heating rod is correlated with, arouse the liquid needle install in inside the heating piece.
The heat preservation needle fixing seat is fixed on the excitation liquid fixing seat, and the excitation liquid fixing seat is provided with a stepped hole matched with the heat preservation needle fixing seat; the heat preservation needle fixing seat is provided with an installation through hole matched with the excitation liquid needle; the exciting liquid needle is provided with a taper hole fixed with the heating block; the bottom of the heating block is provided with a groove matched with the exciting liquid needle, the top of the heating block is provided with a temperature sensor mounting hole, the outer ring of the heating block is provided with a spiral groove, and the inner ring of the heating block is provided with a through hole for mounting a heating rod; and a through hole for installing the excitation liquid needle is formed in the heating rod.
Further, the waste liquid needle assembly comprises a nut seat, a liquid absorption column, a liquid absorption beam and a liquid absorption needle, wherein the nut seat is matched with the Z-direction moving screw rod motor, the liquid absorption column is fixedly installed at the upper end of the nut seat, the liquid absorption beam is fixedly installed at the upper end of the liquid absorption column, and the liquid absorption needle is fixedly installed at one end of the liquid absorption beam; and a Z-direction guide rail is arranged on the front baffle, and the side surface of the nut seat is in sliding connection with the Z-direction guide rail through a sliding block.
Furthermore, an X-direction photoelectric switch is mounted on the front baffle plate, a stop block is mounted on the cup seat, the X-direction photoelectric switch is associated with the X-direction moving motor, and the X-direction photoelectric switch controls the operation of the X-direction moving motor by identifying the position of the stop block; the X-direction photoelectric switch can realize automatic control of the moving position of the cup holder;
the front baffle is provided with a Z-direction photoelectric switch, the nut seat of the waste liquid needle assembly is provided with an induction sheet, the Z-direction photoelectric switch is associated with the Z-direction moving screw rod motor, the Z-direction photoelectric switch controls the operation of the Z-direction moving screw rod motor by identifying the position of the induction sheet, and the arrangement of the Z-direction photoelectric switch can realize the automatic control of the moving condition of the waste liquid needle assembly.
One end of a liquid absorption cross beam of the waste liquid needle assembly is provided with a through hole and a threaded hole for fixing a liquid absorption needle, the other end of the liquid absorption cross beam is provided with a circular through hole in clearance fit with the liquid absorption column, and the circular through hole is provided with a screw fastening notch; one end of the liquid absorption column is provided with a stepped surface matched with the liquid absorption beam, and the other end of the liquid absorption column is provided with a stepped surface matched with the nut seat; the nut seat is provided with a circular through hole in clearance fit with the imbibition column, the side edge of the circular through hole is provided with a screw fastening notch, the nut seat is provided with a through hole matched with a Z-direction moving screw rod motor moving nut, the nut seat is provided with an induction sheet mounting hole, the nut seat is fastened with a guide rail sliding block, a guide rail is matched with a front baffle groove, and a front baffle is provided with a photoelectric switch mounting hole.
Furthermore, an upper baffle is arranged at the upper ends of the reading plate and the front baffle, and a cup taking and placing opening and a liquid sucking opening are arranged on the upper baffle. The setting of overhead gage can play dustproof and the effect of protection, gets putting and taking out of reaction cup of being convenient for of setting up of putting the rim of a cup, and the setting of imbibition mouth is convenient for the imbibition needle to absorb the waste liquid that the test was accomplished.
Furthermore, an installation groove is formed in the reading plate, a reading through hole is formed in the installation groove, the optical reading module is matched with the installation groove of the reading plate, a light source hole of the optical reading module is opposite to the reading through hole, a sealing ring is arranged between the light source hole of the optical reading module and the reading through hole, and the arrangement of the sealing ring is more beneficial to the light-emitting reading of the optical reading module; and a light hole and a groove which can be in sliding fit with the reading plate are arranged on the side surface of the cup base.
Further, the bearing wheel be the bearing of taking the flange, the cup with it is fixed through the clamp plate between the hold-in range, the side of cup is equipped with the draw-in groove, the hold-in range is arranged in the draw-in groove, the outside of draw-in groove is passed through the fix with screw the clamp plate.
Furthermore, a spring frame is arranged on the light screen, a spring frame is arranged in the middle of the bottom plate, and two ends of the telescopic spring are respectively connected with the light screen and the spring frame on the bottom plate. The arrangement of the spring frame is convenient for the installation and the fixation of the extension spring.
Furthermore, a shell is installed at the upper end of the bottom plate, the side face of the shell is fixedly installed on the side face of the front baffle, and the nut seat and a screw rod of the Z-direction moving screw rod motor are arranged in the shell.
The invention also discloses a scheduling method of the reading device, which comprises the following steps:
1) when the cup base moves to the limit position, the X-direction photoelectric switch detects the position of the cup base;
2) the reaction cup containing the sample is placed in the cup seat, the X-direction moving motor drives the belt wheel to rotate, the belt wheel drives the synchronous belt to move, the synchronous belt drives the cup seat to move, the X-direction guide rail guides and controls the moving precision of the cup seat, the cup seat pushes the light screen open, the telescopic spring is pulled open, when the side face of the side baffle is in close contact with the side face of the light screen, the reaction cup in the cup seat moves to the position of the optical reading module, and the light hole of the cup seat is over against the light source hole of the optical reading module;
3) a constant temperature is set in the heat preservation component, the exciting liquid needle is opposite to the opening of the reaction cup, and a constant temperature exciting liquid is added into the reaction cup of the cup seat;
4) the optical reading module measures the reaction cup sample and records the test result;
5) after the test is finished, the X-direction moving motor reversely drives the belt pulley to rotate, the belt pulley drives the synchronous belt to reversely move, the synchronous belt reversely drives the cup base to move, the telescopic spring pulls the light screen to reset, and the opening of the reaction cup in the cup base moves to be right below the liquid suction needle of the waste liquid needle assembly;
6) the Z-direction moving screw rod motor drives the nut seat to move downwards to drive the liquid suction needle of the waste liquid needle assembly to move to the liquid level position of the reaction cup, the tested waste liquid is sucked, and after the waste liquid is sucked, the Z-direction moving screw rod motor rotates reversely to drive the nut seat to move upwards for resetting, namely the waste liquid needle assembly is controlled to move upwards to the position where the Z-direction photoelectric switch detects the induction sheet;
7) the X is to moving motor reverse drive band pulley and rotate, and the band pulley drives hold-in range reverse movement, and the hold-in range reverse drives the cup and removes and reset, and the hold-in range reverse drives the cup and removes to the position that X detected the dog to photoelectric switch promptly.
The invention has the beneficial effects that: the reading device can realize the full automation of reaction cup conveying, exciting liquid adding, reading and waste liquid discharging, the reading device can accurately control the temperature of exciting liquid and improve the exciting effect of exciting liquid, so that when chemiluminescence immunoassay is carried out by directly marking antigens or antibodies through chemiluminescence reagents, the test result is more stable, the error influence of the environment on the result is reduced, the structure is simple, the efficiency is high, the reading is stable, the deviation of the test result is small, and the accuracy is high.
Drawings
FIG. 1 is a schematic structural diagram of a reading device according to an embodiment;
FIG. 2 is a schematic diagram showing the internal structure of the reading device in the embodiment;
FIG. 3 is a schematic structural view between the reading board and the front baffle in the embodiment;
FIG. 4 is an internal cross-sectional view of the insulating assembly in an embodiment;
FIG. 5 is a schematic perspective view of the cup holder in the embodiment;
FIG. 6 is a schematic perspective view of another angle of the cup holder in the embodiment;
FIG. 7 is a schematic structural view of the reading plate in the example;
in the figure, a support rod 1, a bottom plate 2, an optical reading module 3, a 4X-direction moving motor, a 5Z-direction moving screw rod motor, a 6 exciting liquid fixing seat, a 7 shading plate, an 8 cup seat, a 9 waste liquid needle assembly, a 10 reading plate, a 11 front baffle, a 12X-direction guide rail, a 13 expansion spring, a 14 belt wheel, a 15 bearing wheel, a 16 synchronous belt, a 17 heat preservation assembly, an 18Z-direction guide rail, a 19X-direction photoelectric switch, a 20Z-direction photoelectric switch, a 21 upper baffle, a 22 pressing plate, a 23 spring frame, a 24 shell and a 25 side baffle are arranged;
8-1 stop block, 8-2 light transmission holes, 8-3 grooves and 8-4 clamping grooves;
9-1 nut seat, 9-2 liquid absorption column, 9-3 liquid absorption beam, 9-4 liquid absorption needle and 9-5 induction sheet;
10-1 mounting groove and 10-2 reading through hole;
17-1 exciting liquid needle, 17-2 heat preservation needle fixing seat, 17-3 heating block and 17-4 heating rod;
21-1 cup opening and 21-2 liquid suction opening.
Detailed Description
The present invention will be described in detail with reference to the following embodiments in order to make the aforementioned objects, features and advantages of the invention more comprehensible. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.
As shown in the figure, the reading device for the full-automatic chemiluminescence immunoassay analyzer comprises a support rod 1, a bottom plate 2, an optical reading module 3, an X-direction moving motor 4, a Z-direction moving screw rod motor 5, an exciting liquid fixing seat 6, a light shielding plate 7, a cup seat 8 and a waste liquid needle assembly 9;
the upper end of the supporting rod 1 is provided with the bottom plate 2, the bottom plate 2 is provided with the X-direction moving motor 4 and the Z-direction moving screw motor, the upper end of the bottom plate 2 is provided with a reading plate 10 and a front baffle 11, one side of the reading plate 10 is provided with the optical reading module 3, the other side of the reading plate 10 is provided with an X-direction guide rail 12, the side surface of the shading plate 7 is in sliding connection with the X-direction guide rail 12 through a slide block, the shading plate 7 is connected with the middle part of the bottom plate 2 through a telescopic spring 13, and the shading plate 7 and the cup base 8 are both positioned between the reading plate 10 and the front baffle 11;
the X-direction moving motor 4 is mounted at one end of the bottom plate 2, a belt wheel 14 is mounted on a motor shaft of the X-direction moving motor 4, a bearing wheel 15 is mounted at the other end of the bottom plate 2, the belt wheel 14 is connected with the bearing wheel 15 through a synchronous belt 16, the cup base 8 is fixedly mounted on the synchronous belt 16, and the side surface of the cup base 8 is in sliding connection with the X-direction guide rail 12 through a sliding block;
the Z-direction moving screw rod motor 5 drives the waste liquid needle assembly 9 through a nut seat 9-1, a side baffle 25 is installed at the end parts of the reading plate 10 and the front baffle 11, the excitation liquid fixing seat 6 is installed at the upper end of the side baffle 25, a heat insulation component 17 is installed on the excitation liquid fixing seat 6, and an excitation liquid needle 17-1 is installed inside the heat insulation component 17.
The heat preservation assembly 17 comprises a heat preservation needle fixing seat 17-2, a heating block 17-3 is arranged inside the heat preservation needle fixing seat 17-2, a heating rod 17-4 is arranged in the middle of the heating block 17-3, a temperature sensor is arranged at the top of the heating block 17-3, the temperature sensor is associated with the heating rod 17-4, and the excitation liquid needle 17-1 is arranged inside the heating block 17-3.
The waste liquid needle assembly 9 comprises a nut seat 9-1, a liquid absorption column 9-2, a liquid absorption beam 9-3 and a liquid absorption needle 9-4, the nut seat 9-1 is matched with the Z-direction moving screw rod motor 5, the liquid absorption column 9-2 is fixedly installed at the upper end of the nut seat 9-1, the liquid absorption beam 9-3 is fixedly installed at the upper end of the liquid absorption column 9-2, and the liquid absorption needle 9-4 is fixedly installed at one end of the liquid absorption beam 9-3; the front baffle 11 is provided with a Z-direction guide rail 18, and the side surface of the nut seat 9-1 is in sliding connection with the Z-direction guide rail 18 through a sliding block.
An X-direction photoelectric switch 19 is mounted on the front baffle plate 11, a stop block 8-1 is mounted on the cup seat 8, the X-direction photoelectric switch 19 is associated with the X-direction moving motor 4, and the X-direction photoelectric switch 19 controls the operation of the X-direction moving motor 4 by identifying the position of the stop block 8-1;
the front baffle 11 is provided with a Z-direction photoelectric switch 20, the nut seat 9-1 of the waste liquid needle assembly 9 is provided with an induction sheet 9-5, the Z-direction photoelectric switch 20 is associated with the Z-direction moving screw rod motor 5, and the Z-direction photoelectric switch 20 controls the operation of the Z-direction moving screw rod motor 5 by identifying the position of the induction sheet 9-5.
The upper ends of the reading plate 10 and the front baffle plate 11 are provided with an upper baffle plate 21, and the upper baffle plate 21 is provided with a cup taking and placing opening 21-1 and a liquid sucking opening 21-2.
An installation groove 10-1 is formed in the reading plate 10, a reading through hole 10-2 is formed in the installation groove 10-1, the optical reading module 3 is matched with the installation groove 10-1 of the reading plate 10, a light source hole of the optical reading module 3 is over against the reading through hole 10-2, and a sealing ring is arranged between the light source hole of the optical reading module 3 and the reading through hole 10-2; the side surface of the cup base 8 is provided with a light hole 8-2 and a groove 8-3 which can be in sliding fit with the reading board 10.
The bearing wheel 15 is a bearing with a flange, the cup holder 8 and the synchronous belt 16 are fixed through a pressing plate 22, a clamping groove 8-4 is formed in the side face of the cup holder 8, the synchronous belt 16 is arranged in the clamping groove 8-4, and the pressing plate 22 is fixed outside the clamping groove 8-4 through a screw.
The shading plate 7 is provided with a spring frame 23, the middle part of the bottom plate 2 is provided with the spring frame 23, and two ends of the extension spring 13 are respectively connected with the shading plate 7 and the spring frame 23 on the bottom plate 2.
The upper end of the bottom plate 2 is provided with a shell 24, the side surface of the shell 24 is fixedly arranged on the side surface of the front baffle plate 11, and the nut seat 9-1 and a screw rod of the Z-direction moving screw rod motor 5 are arranged in the shell 24.
The scheduling method of the reading device for the full-automatic chemiluminescence immunoassay analyzer comprises the following steps:
1) the cup holder 8 is moved to the limit position; the position of the cup holder 8 is detected by the X-direction photoelectric switch 19;
2) the reaction cup containing the sample is placed in the cup holder 8, the X-direction moving motor 4 drives the belt wheel 14 to rotate, the belt wheel 14 drives the synchronous belt 16 to move, the synchronous belt 16 drives the cup holder 8 to move, the X-direction guide rail 12 guides and controls the movement precision of the cup holder 8, the cup holder 8 pushes the light screen 7 away, the telescopic spring 13 is pulled away, when the side face of the side baffle 25 is in close contact with the side face of the light screen 7, the reaction cup in the cup holder 8 moves to the position of the optical reading module 3, and the light hole 8-2 of the cup holder 8 is over against the light source hole of the optical reading module 3;
3) a constant temperature is set in the heat preservation component 17, the exciting liquid needle 17-1 is opposite to the opening of the reaction cup, and a constant temperature exciting liquid is quantitatively added into the reaction cup of the cup seat 8;
4) the optical reading module 3 measures the reaction cup sample and records the test result;
5) after the test is finished, the X-direction moving motor 4 reversely drives the belt wheel 14 to rotate, the belt wheel 14 drives the synchronous belt 16 to reversely move, the synchronous belt 16 reversely drives the cup base 8 to move, the telescopic spring 13 pulls the light screen 7 to reset, and the opening of the reaction cup in the cup base 8 moves to a position right below the liquid suction needle 9-4 of the waste liquid needle assembly 9;
6) the Z-direction moving screw rod motor 5 drives the nut seat 9-1 to move downwards to drive the liquid suction needle 9-4 of the waste liquid needle assembly 9 to move to the liquid level position of the reaction cup to suck the tested waste liquid, and after the waste liquid is sucked, the Z-direction moving screw rod motor 5 rotates reversely to drive the nut seat 9-1 to move upwards for resetting, namely the waste liquid needle assembly 9 is controlled to move upwards to the position where the Z-direction photoelectric switch 20 detects the induction sheet 9-5;
7) the X-direction moving motor 4 reversely drives the belt wheel 14 to rotate, the belt wheel 14 drives the synchronous belt 16 to reversely move, the synchronous belt 16 reversely drives the cup base 8 to move and reset, namely, the synchronous belt 16 reversely drives the cup base 8 to move to the position where the X-direction photoelectric switch 19 detects the stop block 8-1.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. A reading device for a full-automatic chemiluminescence immunoassay analyzer is characterized by comprising a supporting rod (1), a bottom plate (2), an optical reading module (3), an X-direction moving motor (4), a Z-direction moving screw rod motor (5), an exciting liquid fixing seat (6), a shading plate (7), a cup seat (8) and a waste liquid needle assembly (9);
the upper end of the supporting rod (1) is provided with the bottom plate (2), the bottom plate (2) is provided with the X-direction moving motor (4) and the Z-direction moving screw rod motor (5), the upper end of the bottom plate (2) is provided with a reading plate (10) and a front baffle (11), one side of the reading plate (10) is provided with the optical reading module (3), the other side of the reading plate (10) is provided with an X-direction guide rail (12), the side surface of the shading plate (7) is in sliding connection with the X-direction guide rail (12) through a sliding block, the shading plate (7) is connected with the middle part of the bottom plate (2) through a telescopic spring (13), and the shading plate (7) and the cup base (8) are both positioned between the reading plate (10) and the front baffle (11);
the X-direction moving motor (4) is mounted at one end of the bottom plate (2), a belt wheel (14) is mounted on a motor shaft of the X-direction moving motor (4), a bearing wheel (15) is mounted at the other end of the bottom plate (2), the belt wheel (14) is connected with the bearing wheel (15) through a synchronous belt (16), the cup base (8) is fixedly mounted on the synchronous belt (16), and the side face of the cup base (8) is in sliding connection with the X-direction guide rail (12) through a sliding block;
the Z-direction moving screw rod motor (5) is driven to pass through a nut seat (9-1) to drive the waste liquid needle assembly (9), a side baffle (25) is installed at the end parts of the reading plate (10) and the front baffle (11), the excitation liquid fixing seat (6) is installed at the upper end of the side baffle (25), a heat insulation assembly (17) is installed on the excitation liquid fixing seat (6), and an excitation liquid needle (17-1) is installed inside the heat insulation assembly (17).
2. The reading device for the full-automatic chemiluminescence immunoassay analyzer according to claim 1, wherein the heat preservation assembly (17) comprises a heat preservation needle fixing seat (17-2), a heating block (17-3) is installed inside the heat preservation needle fixing seat (17-2), a heating rod (17-4) is installed in the middle of the heating block (17-3), a temperature sensor is installed on the top of the heating block (17-3) and is associated with the heating rod (17-4), and the excitation liquid needle (17-1) is installed inside the heating block (17-3).
3. The reading device for the full-automatic chemiluminescence immunoassay analyzer according to claim 1, wherein the waste liquid needle assembly (9) comprises a nut seat (9-1), a liquid absorption column (9-2), a liquid absorption beam (9-3) and a liquid absorption needle (9-4), the nut seat (9-1) is matched with the Z-direction moving screw motor (5), the liquid absorption column (9-2) is fixedly arranged at the upper end of the nut seat (9-1), the liquid absorption beam (9-3) is fixedly arranged at the upper end of the liquid absorption column (9-2), and the liquid absorption needle (9-4) is fixedly arranged at one end of the liquid absorption beam (9-3); a Z-direction guide rail (18) is arranged on the front baffle (11), and the side surface of the nut seat (9-1) is in sliding connection with the Z-direction guide rail (18) through a sliding block.
4. The reading device for the full-automatic chemiluminescence immunoassay analyzer according to claim 1, wherein the front baffle (11) is provided with an X-direction photoelectric switch (19), the cup holder (8) is provided with a stopper (8-1), the X-direction photoelectric switch (19) is associated with the X-direction moving motor (4), and the X-direction photoelectric switch (19) controls the operation of the X-direction moving motor (4) by recognizing the position of the stopper (8-1);
the Z-direction photoelectric switch (20) is mounted on the front baffle (11), the sensing piece (9-5) is mounted on the nut seat (9-1) of the waste liquid needle assembly (9), the Z-direction photoelectric switch (20) is associated with the Z-direction moving screw rod motor (5), and the Z-direction photoelectric switch (20) controls the operation of the Z-direction moving screw rod motor (5) by recognizing the position of the sensing piece (9-5).
5. The reading device for the full-automatic chemiluminescence immunoassay analyzer according to claim 1, wherein the upper ends of the reading plate (10) and the front baffle (11) are provided with an upper baffle (21), and the upper baffle (21) is provided with a taking and placing cup opening (21-1) and a liquid sucking opening (21-2).
6. The reading device for the full-automatic chemiluminescence immunoassay analyzer according to claim 1, wherein the reading plate (10) is provided with an installation groove (10-1), the installation groove (10-1) is provided with a reading through hole (10-2), the optical reading module (3) is matched with the installation groove (10-1) of the reading plate (10), the light source hole of the optical reading module (3) is opposite to the reading through hole (10-2), and a sealing ring is arranged between the light source hole of the optical reading module (3) and the reading through hole (10-2); the side surface of the cup seat (8) is provided with a light hole (8-2) and a groove (8-3) which can be in sliding fit with the reading plate (10).
7. The reading device for the full-automatic chemiluminescence immunoassay analyzer according to claim 1, wherein the bearing wheel (15) is a bearing with a flange, the cup holder (8) and the synchronous belt (16) are fixed by a pressing plate (22), a clamping groove (8-4) is arranged on the side surface of the cup holder (8), the synchronous belt (16) is arranged in the clamping groove (8-4), and the pressing plate (22) is fixed outside the clamping groove (8-4) by a screw.
8. The reading device for the full-automatic chemiluminescence immunoassay analyzer according to claim 1, wherein a spring bracket (23) is arranged on the light shielding plate (7), a spring bracket (23) is arranged in the middle of the bottom plate (2), and two ends of the extension spring (13) are respectively connected with the light shielding plate (7) and the spring bracket (23) on the bottom plate (2).
9. The reading device for the full-automatic chemiluminescence immunoassay analyzer according to claim 1, wherein the upper end of the bottom plate (2) is provided with a housing (24), the side surface of the housing (24) is fixedly arranged on the side surface of the front baffle plate (11), and the nut seat (9-1) and the screw of the Z-direction moving screw motor (5) are arranged in the housing (24).
10. A scheduling method for a reading device of a full-automatic chemiluminescence immunoassay analyzer according to any one of claims 1 to 9, wherein the scheduling method comprises the following steps:
1) the cup seat (8) moves to the limit position;
2) the reaction cup containing the sample is placed in a cup seat (8), an X-direction moving motor (4) drives a belt wheel (14) to rotate, the belt wheel (14) drives a synchronous belt (16) to move, the synchronous belt (16) drives the cup seat (8) to move, the X-direction guide rail (12) guides and controls the movement precision of the cup seat (8), the cup seat (8) pushes away a shading plate (7), a telescopic spring (13) is pulled open, when the side surface of a side baffle (25) is tightly contacted with the side surface of the shading plate (7), the reaction cup in the cup seat (8) moves to the position of an optical reading module (3), and a light hole (8-2) of the cup seat (8) is over against a light source hole of the optical reading module (3);
3) a constant temperature is set in the heat preservation component (17), the exciting liquid needle (17-1) is opposite to the opening of the reaction cup, and a constant temperature exciting liquid is quantitatively added into the reaction cup of the cup seat (8);
4) the optical reading module (3) measures the reaction cup sample and records the test result;
5) after the test is finished, the X-direction moving motor (4) reversely drives the belt wheel (14) to rotate, the belt wheel (14) drives the synchronous belt (16) to reversely move, the synchronous belt (16) reversely drives the cup base (8) to move, the telescopic spring (13) pulls the light screen (7) to reset, and the opening of the reaction cup in the cup base (8) moves to the position right below the waste liquid needle assembly (9);
6) the Z-direction moving screw rod motor (5) drives the nut seat (9-1) to move downwards to drive the waste liquid needle assembly (9) to move to the position of the liquid level of the reaction cup, the tested waste liquid is absorbed, and after the waste liquid is absorbed, the Z-direction moving screw rod motor (5) rotates reversely to drive the nut seat (9-1) to move upwards for resetting;
7) the X-direction moving motor (4) reversely drives the belt wheel (14) to rotate, the belt wheel (14) drives the synchronous belt (16) to reversely move, and the synchronous belt (16) reversely drives the cup base (8) to move and reset.
CN202110766159.4A 2021-07-07 2021-07-07 Reading device for full-automatic chemiluminescence immunoassay analyzer and scheduling method thereof Pending CN113311181A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110766159.4A CN113311181A (en) 2021-07-07 2021-07-07 Reading device for full-automatic chemiluminescence immunoassay analyzer and scheduling method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110766159.4A CN113311181A (en) 2021-07-07 2021-07-07 Reading device for full-automatic chemiluminescence immunoassay analyzer and scheduling method thereof

Publications (1)

Publication Number Publication Date
CN113311181A true CN113311181A (en) 2021-08-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110766159.4A Pending CN113311181A (en) 2021-07-07 2021-07-07 Reading device for full-automatic chemiluminescence immunoassay analyzer and scheduling method thereof

Country Status (1)

Country Link
CN (1) CN113311181A (en)

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