CN113311179A - Full-automatic luminous apparatus - Google Patents

Full-automatic luminous apparatus Download PDF

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Publication number
CN113311179A
CN113311179A CN202110724351.7A CN202110724351A CN113311179A CN 113311179 A CN113311179 A CN 113311179A CN 202110724351 A CN202110724351 A CN 202110724351A CN 113311179 A CN113311179 A CN 113311179A
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China
Prior art keywords
bracket
support
automatic
darkroom
motor
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Pending
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CN202110724351.7A
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Chinese (zh)
Inventor
栾培松
张立海
董飒英
孟德明
王朝
高海荣
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Yantai Addcare Bio Tech Ltd
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Yantai Addcare Bio Tech Ltd
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Priority to CN202110724351.7A priority Critical patent/CN113311179A/en
Publication of CN113311179A publication Critical patent/CN113311179A/en
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00306—Housings, cabinets, control panels (details)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00306—Housings, cabinets, control panels (details)
    • G01N2035/00316—Detecting door closure

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The invention relates to a full-automatic luminescence tester, belonging to the technical field of medical equipment, and comprising a shell, a darkroom, a controller, a photomultiplier, a reading head, an X-direction motor, an X-direction belt wheel, an X-direction belt, a Y-direction motor, a Y-direction belt wheel and a bracket, wherein the darkroom and the photomultiplier are arranged in the shell; the X-direction bracket is provided with a bin inlet zero-position photoelectric switch and a bin outlet zero-position photoelectric switch, and the Y-direction bracket is provided with an X-direction sensing sheet; the Y-direction bracket is provided with a longitudinal photoelectric switch, and the bracket is provided with a Y-direction induction sheet. The microplate of the luminescence tester adopts two-point positioning, the whole machine does not need to measure and debug the length of the outlet and inlet bin, and the luminescence tester has simple structure, convenient installation and accurate positioning.

Description

Full-automatic luminous apparatus
Technical Field
The invention relates to a full-automatic luminescence tester, belonging to the technical field of medical equipment.
Background
The luminescence immunoassay technique is a method of detecting an antigen or an antibody by combining a luminescence reaction with an immunoreaction. The sensitivity and the specificity are good by adopting a micro-multiplication technology; the detection range is very wide, and the detection can be carried out from traditional proteins, hormones, enzymes to medicines. The adopted photomultiplier is a vacuum electronic device for converting weak optical signals into electric signals, and can measure infinitesimal radiation power with the wavelength of 200-1200 nanometers in the aspects of low-level photometry and spectroscopy.
For a full-automatic luminescence tester, the positioning of a luminescence microplate is very important, the detection accuracy and the detection efficiency are directly influenced, and the existing luminescence tester usually has errors in the positioning of the microplate or is provided with a large number of accessory component mechanisms so as to realize the positioning of the microplate, so that the equipment structure is complex and the overhaul cost is high.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides a full-automatic luminescence tester, the microplate of the luminescence tester adopts two-point positioning, the whole machine does not need to measure and debug the length of an outlet and an inlet bin, and the full-automatic luminescence tester has simple structure, convenient installation and accurate positioning.
The technical scheme for solving the technical problems is as follows: a full-automatic luminometer comprises a shell, a darkroom, a controller, a photomultiplier, a reading head, an X-direction motor, an X-direction belt wheel, an X-direction belt, a Y-direction motor, a Y-direction belt wheel and a bracket, wherein the darkroom and the photomultiplier are installed inside the shell, the reading head is installed at the end part of the photomultiplier, the reading head is positioned inside the darkroom, and the photomultiplier, the reading head, the X-direction motor and the Y-direction motor are all associated with the controller;
an X-direction support is installed in the darkroom, one end of the X-direction support is provided with the X-direction motor, the other end of the X-direction support is provided with the X-direction belt wheel, the X-direction belt is connected with the X-direction motor and the X-direction belt wheel, and the X-direction belt is fixedly provided with a Y-direction support; the Y-direction motor is mounted on the Y-direction support, the Y-direction belt is connected with the Y-direction motor and the Y-direction belt wheel, the Y-direction belt is fixedly provided with the bracket, and the upper end of the bracket is provided with the micro-plate;
one end of the X-direction support is provided with a bin inlet zero-position photoelectric switch, the other end of the X-direction support is provided with a bin outlet zero-position photoelectric switch, and the Y-direction support is provided with an X-direction induction sheet; and a longitudinal photoelectric switch is arranged on the Y-direction support, and a Y-direction induction sheet is arranged on the bracket.
The invention has the beneficial effects that: the luminescence tester reads the samples in the microplate by utilizing the working principle of the photomultiplier, and the sample reading of each micropore in the microplate by the reading head is realized by utilizing the operation of the X-direction motor and the Y-direction motor. The positioning of the microplate adopts two-point positioning of an inlet zero position and an outlet zero position, when the luminescence tester runs, the microplate enters one zero point, the outlet stop position is the other zero point, the whole machine does not need to measure and debug the outlet length, the two zero positions do not need to be specially calculated when in use, the installation is convenient, the structure is simple, and the reading positioning is accurate.
On the basis of the technical scheme, the invention can be further improved as follows:
furthermore, an X-direction track is arranged on the X-direction support, and the Y-direction support is in sliding connection with the X-direction track;
the Y-direction support is provided with a Y-direction track, the other end of the Y-direction track is provided with a Y-direction belt wheel, and the lower end of the bracket is in sliding connection with the Y-direction track.
The beneficial effect of adopting the further scheme is that: the X-direction track and the Y-direction track are arranged, so that the movement of the micro-plate in the X direction and the Y direction is guided by adopting a linear guide rail mode, and the operation process is more stable.
Further, the darkroom and the side of shell between be equipped with out the door frame, the upper end of bracket is equipped with the board groove, place the flitch in the board groove, be equipped with the spout on the bracket, the spout with the board groove communicates with each other, install in the spout and press from both sides tight piece, the upper end of pressing from both sides tight piece is equipped with the door frame fixture block, the support piece is installed to the spout lower extreme, and the support piece can hold and press from both sides tight piece, prevents to press from both sides tight piece and drop, install the torsional spring on the support piece, a torsion arm of torsional spring is connected press from both sides tight piece.
The beneficial effect of adopting the further scheme is that: when the micro-plate is pushed out of the darkroom, the door frame clamping block is clamped by the door frame, so that the clamping block is separated from the micro-plate, and a worker can freely take up the micro-plate; when the microplate was impeld the darkroom, under the effect of torsional spring, the clamp tight piece compresses tightly the microplate to make whole reading in-process, the microplate can be more stable, avoids the microplate to shift because of the machine vibrations.
Furthermore, go out the lower extreme of door frame and install the automatically-controlled door, the lower extreme of automatically-controlled door with it rotates to connect to go out the door frame, it is equipped with rectangular through-hole on the door frame to go out, the automatically-controlled door with the darkroom bottom is passed through extension spring and is connected, rectangular through-hole supplies extension spring passes through.
The beneficial effect of adopting the further scheme is that: the automatic door is connected with the frame of going out to the installation extension spring makes when the flitch is released, and the bracket can be opened the automatic door top, and when the flitch was promoted the darkroom, the automatic door self-closing under extension spring's effect guaranteed lighttight in the darkroom, simple structure, practical convenient.
Further, the lower extreme of bracket is installed the layer board, the layer board is located the below in board groove, the board inslot is installed the hot plate.
The beneficial effect of adopting the further scheme is that: the heating plate is arranged to facilitate the heating treatment of the lower part of the micro-plate.
Further, the inside side-mounting of darkroom has the link, the link side is equipped with the slide rail, it has the reading frame to slide on the side slide rail of link, the reading frame with pass through the bolt fastening between the link, the upper end installation of reading frame the reading head.
The beneficial effect of adopting the further scheme is that: the reading frame and the connecting frame are structurally arranged, so that the height of the reading head can be conveniently adjusted, and the applicability of the luminescence tester is stronger.
Furthermore, the upper end of the reading frame is provided with a heating plate.
The beneficial effect of adopting the further scheme is that: the heating plate is arranged on the reading frame, so that the heating treatment is conveniently carried out on the upper part of the micro-plate, and the practicability is stronger.
Furthermore, a pressure spring is arranged in the reading head.
The beneficial effect of adopting the further scheme is that: a pressure spring is selected in the reading head, so that in the reading process, the reading head can be properly pressed on the micro-plate, a gap cannot be generated between the reading head and the micro-plate, the reading head cannot be pressed on the micro-plate, and the motor loses steps in the movement process of the micro-plate.
Furthermore, the shell is provided with a plurality of heat dissipation holes, and the lower end of the shell is provided with a supporting leg.
The beneficial effect of adopting the further scheme is that: the setting of louvre is convenient for give off to the inside temperature of light emission apparatus, and the setting of supporting legs is convenient for the support to light emission apparatus, and the balance adjustment of the light emission apparatus of being convenient for also avoids the mesa to have water to lead to light emission apparatus to intake.
Drawings
FIG. 1 is a schematic view showing an external structure of a luminescence measuring apparatus according to an embodiment;
FIG. 2 is a schematic view showing the internal structure of a housing of the luminescence measuring apparatus according to the embodiment;
FIG. 3 is a schematic view showing the internal structure of a darkroom of the luminometer according to the embodiment;
FIG. 4 is a schematic structural view of the microplate in the example when it is completely ejected;
FIG. 5 is a schematic structural diagram of the X-direction support and the Y-direction support in the embodiment;
FIG. 6 is a perspective view of the bracket according to the embodiment;
FIG. 7 is a schematic perspective view of another angle of the bracket of the embodiment;
FIG. 8 is a schematic structural view of the clamping block and the torsion spring according to the embodiment;
FIG. 9 is a schematic structural view of the automatic door and the extension spring according to the embodiment;
FIG. 10 is a schematic structural view of the connection frame and the reading frame in the embodiment;
in the figure, 1 shell, 2 darkroom, 3 photomultiplier, 4 reading head, 5X direction motor, 6X direction belt wheel, 7X direction belt, 8Y direction motor, 9Y direction belt, 10Y direction belt wheel, 11 bracket, 12X direction bracket, 13Y direction bracket, 14 micro-plate, 15 warehousing zero position photoelectric switch, 16 warehousing zero position photoelectric switch, 17X direction induction sheet, 18 longitudinal photoelectric switch, 19Y direction induction sheet, 20X direction rail, 21Y direction rail, 22 door frame, 23 plate groove, 24 chute, 25 clamping block, 26 door frame clamping block, 27 support sheet, 28 torsion spring, 29 automatic door, 30 strip through hole, 31 heat dissipation hole extension spring, 32 support plate, 33 connecting frame, 34 reading frame, 35, 36 supporting foot.
Detailed Description
The present invention will be described in detail with reference to the following embodiments in order to make the aforementioned objects, features and advantages of the invention more comprehensible. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.
As shown in the figure, the full-automatic luminometer comprises a shell 1, a darkroom 2, a controller, a photomultiplier tube 3, a reading head 4, an X-direction motor 5, an X-direction belt wheel 6, an X-direction belt 7, a Y-direction motor 8, a Y-direction belt 9, a Y-direction belt wheel 10 and a bracket 11, wherein the darkroom 2 and the photomultiplier tube 3 are installed inside the shell 1, the reading head 4 is installed at the end part of the photomultiplier tube 3, the reading head 4 is positioned inside the darkroom 2, and the photomultiplier tube 3, the reading head 4, the X-direction motor 5 and the Y-direction motor 8 are all associated with the controller;
an X-direction support 12 is installed in the darkroom 2, the X-direction motor 5 is installed at one end of the X-direction support 12, the X-direction belt wheel 6 is installed at the other end of the X-direction support 12, the X-direction belt 7 is connected with the X-direction motor 5 and the X-direction belt wheel 6, and a Y-direction support 13 is fixedly installed on the X-direction belt 7; the Y-direction motor 8 is mounted on the Y-direction support 13, the Y-direction belt 9 is connected with the Y-direction motor 8 and the Y-direction belt wheel 10, the Y-direction belt 9 is fixedly mounted with the bracket 11, and the upper end of the bracket 11 is provided with the microplate 14;
one end of the X-direction support 12 is provided with a warehousing zero-position photoelectric switch 15, the other end of the X-direction support 12 is provided with a warehousing zero-position photoelectric switch 16, and the Y-direction support 13 is provided with an X-direction induction sheet 17; the Y-direction support 13 is provided with a longitudinal photoelectric switch 18, and the bracket 11 is provided with a Y-direction induction sheet 19.
An X-direction track 20 is arranged on the X-direction support 12, and the Y-direction support 13 is in sliding connection with the X-direction track 20; the Y-direction support 13 is provided with a Y-direction track 21, the other end of the Y-direction track 21 is provided with the Y-direction belt wheel 10, and the lower end of the bracket 11 is in sliding contact with the Y-direction track 21.
Darkroom 2 and shell 1's side between be equipped with out door frame 22, the upper end of bracket 11 is equipped with board groove 23, place flitch 14 in the board groove 23, be equipped with spout 24 on the bracket 11, spout 24 with board groove 23 communicates with each other, install in the spout 24 and press from both sides tight piece 25, the upper end of pressing from both sides tight piece 25 is equipped with door frame fixture block 26, the support piece 27 is installed to spout 24 lower extreme, install torsional spring 28 on the support piece 27, torsional spring 28's a torsion arm is connected press from both sides tight piece 25. A supporting plate 32 is mounted at the lower end of the bracket 11, the supporting plate 32 is located below the plate groove 23, and a heating plate is mounted in the plate groove 23.
As shown in fig. 4, when the microplate 14 is pushed out of the darkroom 2, the door frame latch 26 is latched by the door frame 22, so that the clamping block 25 is separated from the microplate 14, and the worker can freely take up the microplate 14; as shown in fig. 3, when the microplate 14 is pushed into the dark room 2, the clamping block 25 presses the microplate 14 under the action of the torsion spring 28, so that the microplate 14 can be more stable in the whole reading process, the microplate 14 is prevented from being displaced due to the vibration of the machine, and the reading head 4 is beneficial to accurate reading.
Go out the lower extreme of door frame 22 and install automatically-controlled door 29, automatically-controlled door 29's lower extreme with it rotates to be connected to go out door frame 22, it is equipped with rectangular through-hole 30 on the door frame 22 to go out, automatically-controlled door 29 with 2 bottoms in darkroom are connected through extension spring 31, rectangular through-hole 30 supplies extension spring 31 passes through. The carriage 11 can push the automatic door 29 open when the microplate 14 is pushed out, and the automatic door 29 is automatically closed by the action of the extension spring 31 when the microplate 14 is pushed into the dark room 2.
2 inside side-mounting in darkroom has link 33, link 33 side is equipped with the slide rail, it has reading frame 34 to slide on the side slide rail of link 33, reading frame 34 with pass through the bolt fastening between the link 33, the upper end installation of reading frame 34 reading head 4. The upper end of the reading frame 34 is provided with a heating plate. The pressure spring is arranged in the reading head 4, so that in the reading process, the reading head 4 can be properly pressed on the micro-plate 14, a gap cannot be generated between the reading head 4 and the micro-plate 14, the reading head 4 cannot be pressed on the micro-plate 14, the X-direction motor 5 or the Y-direction motor 8 can be lost in the moving process of the micro-plate 14, and the reading of the reading head 4 is accurate.
A plurality of heat dissipation holes 35 are formed in the housing 1, and supporting legs 36 are mounted at the lower end of the housing 1.
The luminescence tester reads the sample in the microplate 14 by using the working principle of the photomultiplier tube 3, and the sample reading of each micropore in the microplate 44 by the reading head 4 is realized by using the operation of the X-direction motor 5 and the Y-direction motor 8. The positioning of the microplate 14 adopts the internal and external two-point positioning of the warehousing zero-position photoelectric switch 15 and the ex-warehouse zero-position photoelectric switch 16, when the luminescence tester runs, the microplate 14 enters one zero point, and the ex-warehouse stop position is the other zero point, so that the whole machine does not need to measure and debug the ex-warehouse length, and the two zero points do not need special calculation when in use, thereby having convenient installation, simple structure and accurate reading and positioning.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (9)

1. The full-automatic luminescence tester is characterized by comprising a shell (1), a darkroom (2), a controller, a photomultiplier (3), a reading head (4), an X-direction motor (5), an X-direction belt wheel (6), an X-direction belt (7), a Y-direction motor (8), a Y-direction belt (9), a Y-direction belt wheel (10) and a bracket (11), wherein the darkroom (2) and the photomultiplier (3) are installed inside the shell (1), the reading head (4) is installed at the end part of the photomultiplier (3), the reading head (4) is located inside the darkroom (2), and the photomultiplier (3), the reading head (4), the X-direction motor (5) and the Y-direction motor (8) are all associated with the controller;
an X-direction support (12) is installed in the darkroom (2), one end of the X-direction support (12) is provided with the X-direction motor (5), the other end of the X-direction support (12) is provided with the X-direction belt wheel (6), the X-direction belt (7) is connected with the X-direction motor (5) and the X-direction belt wheel (6), and a Y-direction support (13) is fixedly installed on the X-direction belt (7); the Y-direction motor (8) is mounted on the Y-direction support (13), the Y-direction belt (9) is connected with the Y-direction motor (8) and the Y-direction belt wheel (10), the Y-direction belt (9) is fixedly mounted with the bracket (11), and the upper end of the bracket (11) is provided with the microplate (14);
one end of the X-direction support (12) is provided with a warehousing zero-position photoelectric switch (15), the other end of the X-direction support (12) is provided with a warehousing zero-position photoelectric switch (16), and the Y-direction support (13) is provided with an X-direction induction sheet (17); the Y-direction support (13) is provided with a longitudinal photoelectric switch (18), and the bracket (11) is provided with a Y-direction induction sheet (19).
2. The full-automatic luminometer according to claim 1, wherein the X-direction support (12) is provided with an X-direction rail (20), and the Y-direction support (13) is in sliding connection with the X-direction rail (20);
the Y-direction support (13) is provided with a Y-direction track (21), the other end of the Y-direction track (21) is provided with the Y-direction belt wheel (10), and the lower end of the bracket (11) is in sliding connection with the Y-direction track (21).
3. The full-automatic luminometer according to claim 1, wherein a door frame (22) is arranged between the side ends of the darkroom (2) and the housing (1), a plate groove (23) is arranged at the upper end of the bracket (11), a micro plate (14) is arranged in the plate groove (23), a sliding groove (24) is arranged on the bracket (11), the sliding groove (24) is communicated with the plate groove (23), a clamping block (25) is arranged in the sliding groove (24), a door frame clamping block (26) is arranged at the upper end of the clamping block (25), a supporting sheet (27) is arranged at the lower end of the sliding groove (24), a torsion spring (28) is arranged on the supporting sheet (27), and a torsion arm of the torsion spring (28) is connected with the clamping block (25).
4. The full-automatic luminometer according to claim 3, wherein an automatic door (29) is installed at the lower end of the outgoing door frame (22), the lower end of the automatic door (29) is rotatably connected with the outgoing door frame (22), a strip through hole (30) is formed in the outgoing door frame (22), the automatic door (29) is connected with the bottom of the darkroom (2) through an extension spring (31), and the strip through hole (30) is used for the extension spring (31) to pass through.
5. The full-automatic luminometer according to claim 3, wherein a support plate (32) is installed at the lower end of the bracket (11), the support plate (32) is located below the plate groove (23), and a heating plate is installed in the plate groove (23).
6. The full-automatic luminometer according to claim 1, wherein a connecting frame (33) is installed on the inner side of the darkroom (2), a sliding rail is arranged on the side of the connecting frame (33), a reading frame (34) is connected onto the sliding rail on the side of the connecting frame (33), the reading frame (34) and the connecting frame (33) are fixed through bolts, and the reading head (4) is installed at the upper end of the reading frame (34).
7. The automatic luminometer according to claim 6, wherein a heating plate is installed at the upper end of the reading frame (34).
8. The automatic luminometer according to claim 6, wherein the reading head (4) is internally provided with a compression spring.
9. The automatic light-emitting tester according to claim 1, wherein the housing (1) has a plurality of heat dissipation holes (35), and the lower end of the housing (1) is provided with a supporting leg (36).
CN202110724351.7A 2021-06-29 2021-06-29 Full-automatic luminous apparatus Pending CN113311179A (en)

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Application Number Priority Date Filing Date Title
CN202110724351.7A CN113311179A (en) 2021-06-29 2021-06-29 Full-automatic luminous apparatus

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CN215066724U (en) * 2021-06-29 2021-12-07 烟台艾德康生物科技有限公司 Full-automatic luminous apparatus
CN115267235A (en) * 2022-08-23 2022-11-01 苏州宇测生物科技有限公司 Sample introduction module and single-molecule immunoassay analyzer comprising same

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* Cited by examiner, † Cited by third party
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CN114526678A (en) * 2022-02-24 2022-05-24 长光（沧州）光栅传感技术有限公司 Quick detection device of grating ruler reading head signal
CN114526678B (en) * 2022-02-24 2023-09-22 长光（沧州）光栅传感技术有限公司 Quick detection device for grating ruler reading head signals

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