CN113865699B - Chemiluminescence immunoassay appearance reading device - Google Patents
Chemiluminescence immunoassay appearance reading device Download PDFInfo
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- CN113865699B CN113865699B CN202111456589.2A CN202111456589A CN113865699B CN 113865699 B CN113865699 B CN 113865699B CN 202111456589 A CN202111456589 A CN 202111456589A CN 113865699 B CN113865699 B CN 113865699B
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- 238000003018 immunoassay Methods 0.000 title claims abstract description 25
- 238000001514 detection method Methods 0.000 claims abstract description 212
- 239000007788 liquid Substances 0.000 claims abstract description 17
- 238000002347 injection Methods 0.000 claims abstract description 13
- 239000007924 injection Substances 0.000 claims abstract description 13
- 230000005540 biological transmission Effects 0.000 claims description 13
- 230000005284 excitation Effects 0.000 claims description 11
- 230000003287 optical effect Effects 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 230000000903 blocking effect Effects 0.000 claims description 6
- 238000010586 diagram Methods 0.000 description 11
- 230000033001 locomotion Effects 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000004020 luminiscence type Methods 0.000 description 2
- 230000001960 triggered effect Effects 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000036046 immunoreaction Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000007517 polishing process Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
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- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
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- G—PHYSICS
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- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J1/00—Photometry, e.g. photographic exposure meter
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J1/00—Photometry, e.g. photographic exposure meter
- G01J1/02—Details
- G01J1/0214—Constructional arrangements for removing stray light
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J1/00—Photometry, e.g. photographic exposure meter
- G01J1/02—Details
- G01J1/04—Optical or mechanical part supplementary adjustable parts
- G01J1/0403—Mechanical elements; Supports for optical elements; Scanning arrangements
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J1/00—Photometry, e.g. photographic exposure meter
- G01J1/02—Details
- G01J1/04—Optical or mechanical part supplementary adjustable parts
- G01J1/0407—Optical elements not provided otherwise, e.g. manifolds, windows, holograms, gratings
- G01J1/0433—Optical elements not provided otherwise, e.g. manifolds, windows, holograms, gratings using notch filters
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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Abstract
The invention belongs to the field of medical detection, and particularly relates to a reading device of a chemiluminescence immunoassay analyzer, which comprises a supporting leg and a box body, wherein a cup placing hole and an exciting liquid injection needle are arranged on the box body, and the reading device further comprises: the detection cup support reciprocates among the cup placing hole, the reading mechanism and the cup throwing mechanism and completes the actions of placing, reading and throwing the detection cup, and the shading mechanism shades the detection cup when the reading of the detection cup is detected. The invention also provides a reading device of the chemiluminescence immunoassay analyzer, wherein two cup placing holes are formed in the detection cup bracket, and two detection cups can be placed in the detection cup bracket at the same time; meanwhile, the invention adopts a driving mechanism to drive the detection cup bracket and the shading mechanism to act simultaneously, and the detection cup after reading can be automatically discarded by combining the cup throwing mechanism, so that the use is convenient, and the detection efficiency and the detection accuracy are improved by double-cup detection.
Description
Technical Field
The invention belongs to the field of medical detection, and particularly relates to a reading device of a chemiluminescence immunoassay analyzer.
Background
The chemiluminescence immunoassay analyzer is a medical detection instrument for immunoassay by detecting serum, and can be used for detection and analysis of various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins, drugs and the like by combining chemiluminescence measurement technology with high sensitivity and high specificity immunoreaction.
Chemiluminescence immunoassay is carried out by directly labeling an antigen or an antibody with a chemiluminescence reagent. And adding an exciting liquid into the reaction sample, and measuring the luminous value of the sample. The excitation liquid needs to be carried out in a dark environment when the excitation luminescence reaction is carried out, and if the excitation liquid cannot be completely shielded from light, the test result generates errors.
The luminescence immunoassay appearance detects and goes on incubating the dish mostly, drives the reaction cup by incubating the dish and reachs the detection position, and the application of sample is to the reaction cup application of sample, is shaded all around the reaction cup by driving motor drive baffle again, forms the darkroom, and the mechanism is complicated and removes the baffle again and shelter from forming the darkroom after detecting the cup and carry the detection department, and the part of motion is more, causes easily that to be in the light not tight, shelters from the difficulty.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides a reading device of a chemiluminescence immunoassay analyzer.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides a chemiluminescence immunoassay appearance reading device, includes supporting leg and box, is provided with on the box and puts a hole and arouse liquid injection needle, puts a hole and is used for putting into the detection cup, still includes:
the driving mechanism is arranged in the box body;
the reading mechanism is arranged in the box body and is used for reading the detection cup;
the cup throwing mechanism is arranged in the box body and is used for throwing the detected detection cup;
the detection cup support is connected with the driving mechanism and is provided with a cup placing hole, and the cup placing hole is used for placing the detection cup;
the light shading mechanism is connected with the driving mechanism, the detection cup support reciprocates among the cup placing hole, the reading mechanism and the cup throwing mechanism and completes the actions of placing, reading and throwing the detection cup, and the light shading mechanism shades the detection cup when the reading of the detection cup is detected.
The further technical scheme is as follows: when the detection cup reads, the detection cup support and the shading mechanism move oppositely, and when the detection cup reaches the reading mechanism, the shading mechanism moves to the cup opening of the detection cup or the cup placing hole to shade.
The further technical scheme is as follows: the driving mechanism comprises a driving piece and a transmission piece, the transmission piece is in belt transmission or chain transmission, the detection cup support and the shading mechanism are respectively arranged on two sides of the transmission piece, and the detection cup support and the shading mechanism synchronously move and are opposite in direction.
The further technical scheme is as follows: the reading mechanism comprises a photon counter, a steering engine is arranged on the side face of the photon counter, a lens switching frame is arranged on the steering engine, the middle of the lens switching frame rotates along with the steering engine, an optical filter is arranged at one end of the lens switching frame, and a baffle is arranged at the other end of the lens switching frame.
The further technical scheme is as follows: the lower part of the detection cup support is connected with the driving mechanism, the bottom of the detection cup support is connected with the box body through a sliding block and a guide rail, the upper part of the detection cup support is provided with the cup placing hole, and one side of the cup placing hole is provided with the cup throwing groove.
The further technical scheme is as follows: the detection cup is characterized in that a guide strip is arranged on the inner side wall of the box body, one side, provided with a cup throwing groove, of the detection cup support is clamped on the guide strip, and the guide strip is horizontally arranged on the upper portion of the reading mechanism and is stopped at the cup throwing mechanism.
The further technical scheme is as follows: the cup throwing mechanism comprises a cup throwing guide block connected with the box body, an inclined plane is arranged on the cup throwing guide block and corresponds to the part, extending out of the cup placing hole, of the detection cup, and a discarding channel is further arranged on the box body and corresponds to the position of the cup throwing guide block.
The further technical scheme is as follows: the side wall of the box body is provided with an in-place detection sensor, and the side surface of the detection cup support is provided with a detection blocking sheet corresponding to the side surface of the detection cup support.
The further technical scheme is as follows: the lower part of the shading mechanism is connected with the driving mechanism, the upper part of the shading mechanism is horizontally provided with a shading plate, the bottom of the shading mechanism is also provided with rollers, and the side surface of the shading mechanism is connected with the box body through a sliding block and a guide rail.
The invention also provides a reading device of the chemiluminescence immunoassay analyzer, which comprises supporting legs and a box body, wherein the box body is provided with a cup placing hole and an exciting liquid injection needle, the cup placing hole is used for placing a detection cup, and the reading device also comprises:
the driving mechanism is arranged in the box body;
the reading mechanism is arranged in the box body and is used for reading the detection cup;
the cup throwing mechanism is arranged on the box body and is used for throwing the detected detection cup;
the detection cup bracket is connected with the driving mechanism and is provided with two cup placing holes, and an excitation liquid injection needle arranged on the box body corresponds to the detection cup;
the light shading mechanism is connected with the driving mechanism, the detection cup support reciprocates among the cup placing hole, the reading mechanism and the cup throwing mechanism and completes the placing, reading and throwing actions of the detection cup, and the light shading mechanism shades the detection cup when the reading of the detection cup is detected;
when the reading mechanism reads the first detection cup, the shading mechanism moves to the cup opening of the detection cup to shade light; when the reading mechanism reads the second detection cup, the shading mechanism moves to the cup placing hole to shade light.
Compared with the prior art, the invention has the following beneficial effects:
(1) according to the reading device of the chemiluminescence immunoassay analyzer, the driving mechanism drives the detection cup bracket and the shading mechanism to move, and the shading mechanism shades the detection cup when the detection cup reads, so that the influence of external light is avoided, and the reading accuracy is improved; meanwhile, the driving mechanism is adopted to drive the detection cup bracket and the shading mechanism to act simultaneously, so that the operation is convenient; the combination of the cup throwing mechanism can automatically throw the read detection cup, so that the use is convenient;
(2) when the detection cup is in the reading process, on one hand, the detection cup and the shading mechanism move oppositely, the shading mechanism can shade the detection cup when the detection cup moves to the overlapping position, and the detection cup just moves to the reading mechanism for reading at the moment, so that the detection accuracy is facilitated, and on the other hand, the shading mechanism can also reach the cup placing hole when the detection cup moves to the reading mechanism, so that the whole interior of the box body is in a shading environment, and the shading effect is also achieved;
(3) the reading mechanism comprises a photon counter, a steering engine and a lens switching frame, the lens switching frame can rotate under the control of the steering engine, one end with an optical filter or the closed end of the lens switching frame is rotated to the position of the photon counter, and when the lens switching frame is not used, the photon counter can be closed to be protected from light, so that the damage is avoided; meanwhile, in the using process, one end with the optical filter can be transferred to a photon counter, and the detection performance of the instrument can be improved by matching with the optical filters with different multiplying powers;
(4) the guide rail and the sliding block arranged at the bottom of the detection cup bracket can provide support, and meanwhile, the stable movement of the detection cup bracket is facilitated; a cup placing hole is formed in the detection cup support, and a cup throwing groove is formed in the side face of the cup placing hole, so that a cup can be conveniently thrown; the guide strip arranged on the box body can laterally support the detection cup in the cup placing hole, so that the detection cup is prevented from moving, the reading mechanism is facilitated to read, the guide strip is stopped at the cup throwing mechanism, and the detection cup can conveniently withdraw from the cup throwing groove;
(5) the cup throwing mechanism comprises a cup throwing guide block, an inclined plane is arranged on the cup throwing guide block, when the detection cup support moves to the cup throwing mechanism, a cup throwing groove on the detection cup support leaves the guide strip, the part of the detection cup extending out of the detection cup support moves along the inclined plane under the action of the cup throwing guide block and exits the cup placing hole through the cup throwing groove, and finally enters the discarding channel for discarding, so that the cup throwing mechanism is convenient to use; meanwhile, the box body is also provided with an in-place detection sensor, when the detection cup support moves to a certain position, the detection cup is completely withdrawn and the in-place detection sensor is triggered, and the cup throwing action is finished;
(6) the invention also provides a reading device of the chemiluminescence immunoassay analyzer, wherein two cup placing holes are formed in the detection cup bracket, the detection objects of the detection cups in the two cup placing holes can be the same or different, and the excitation liquid injection needle arranged on the box body corresponds to the detection cup; in the process of moving the shading mechanism and the detection cup bracket, when the first detection cup reads, the shading mechanism and the detection cup bracket move oppositely and are just positioned at the cup opening of the first detection cup, and shading treatment is carried out on the detection cup; when the second detection cup reads, the shading mechanism continues to move to the cup placing hole, the whole interior of the box body is in a light-shading environment, the shading effect is achieved, the two detection cups can be in the light-shading environment when reading, and the accuracy of detection reading can be effectively improved; meanwhile, the detection and the shading of the two detection cups can be realized through one driving mechanism, and the structure is simple; the double-cup detection can simultaneously detect two different detection objects, and improves the detection efficiency and the accuracy.
The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical means of the present invention more clearly understood, the present invention may be implemented according to the content of the description, and in order to make the above and other objects, features, and advantages of the present invention more apparent, the following detailed description will be given of preferred embodiments.
Drawings
Fig. 1 is a schematic structural diagram of a first embodiment of the present invention.
Fig. 2 is a schematic structural diagram of another angle according to an embodiment of the present invention.
Fig. 3 is a first schematic structural diagram of the interior of the box body according to the first embodiment of the invention.
Fig. 4 is a second schematic structural diagram of the interior of the box body in the first embodiment of the invention.
Fig. 5 is a schematic mechanism diagram of a reading mechanism according to an embodiment of the invention.
Fig. 6 is a schematic structural diagram of a detection cup holder according to a first embodiment of the invention.
Fig. 7 is a first schematic structural diagram of a reading according to a first embodiment of the present invention.
Fig. 8 is a second schematic structural diagram of the first embodiment of the present invention during reading.
Fig. 9 is a schematic structural view of a cup polishing process according to an embodiment of the invention.
FIG. 10 is a schematic structural diagram of the first detecting cup for reading according to the second embodiment of the present invention.
FIG. 11 is a schematic structural diagram of a second inspection cup according to a second embodiment of the present invention.
Fig. 12 is a schematic structural diagram of a cup-throwing operation according to a second embodiment of the present invention.
The reference numbers in the figures are:
100. supporting legs;
200. a box body; 210. placing a cup hole; 220. an exciting liquid injection needle; 230. a guide strip; 240. an in-place detection sensor;
300. detecting the cup;
400. a drive mechanism; 410. a drive member; 420. a transmission member;
500. a reading mechanism; 510. a photon counter; 520. a steering engine; 530. a lens switching frame; 540. an optical filter;
600. a cup throwing mechanism; 610. a cup throwing guide block; 620. discarding the channel;
700. detecting a cup holder; 710. placing a cup hole; 720. a cup throwing groove; 730. detecting a blocking piece;
800. a light-shielding mechanism; 810. a visor; 820. a roller;
900. a side blocking piece.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings.
The first embodiment is as follows:
as shown in fig. 1 to 9, a chemiluminescence immunoassay analyzer reading device comprises a support leg 100 and a box 200, wherein the box 200 is provided with a cup hole 210 and an excitation liquid injection needle 220, the cup hole 210 is used for placing a detection cup 300, and the chemiluminescence immunoassay analyzer reading device further comprises:
a driving mechanism 400 disposed in the case 200;
a reading mechanism 500 disposed in the case 200 and configured to read the detection cup 300;
the cup throwing mechanism 600 is arranged in the box body 200 and is used for throwing away the detected detection cup 300;
the detection cup bracket 700 is connected with the driving mechanism 400 and is provided with a cup placing hole 710, and the cup placing hole 710 is used for placing the detection cup 300;
the light shielding mechanism 800 is connected with the driving mechanism 400, the detection cup support 700 reciprocates among the cup placing hole 210, the reading mechanism 500 and the cup throwing mechanism 600 and completes the placing, reading and cup throwing actions of the detection cup 300, and the light shielding mechanism 800 shields the detection cup 300 when reading.
The invention provides a reading device of a chemiluminescence immunoassay analyzer, wherein a driving mechanism 400 drives a detection cup bracket 700 and a shading mechanism 800 to move, and the shading mechanism 800 shades a detection cup 300 when the detection cup reads, so that the influence of external light is avoided, and the reading precision is improved; meanwhile, the same driving mechanism 400 is adopted to drive the detection cup bracket 700 and the shading mechanism 800 to act simultaneously, so that the operation is convenient; the cup throwing mechanism 600 is combined, so that the detection cup after reading can be automatically discarded, and the use is convenient.
Specifically, the cup throwing mechanism 600 and the reading mechanism 500 in this embodiment may be respectively disposed on two sides of the cup placing hole 210, or may be disposed on the same side of the cup placing hole 210, and in this embodiment, the reading mechanism 500 and the cup throwing mechanism 600 are disposed on two sides of the cup placing hole 210.
Preferably, the detection cup holder 700 and the light shielding mechanism 800 move towards each other during the reading process of the detection cup 300, and when the detection cup 300 reaches the reading mechanism 500, the light shielding mechanism 800 moves to the cup opening or the cup placing hole 210 of the detection cup 300 for shielding light.
Further preferably, the driving mechanism 400 includes a driving member 410 and a transmission member 420, the transmission member 420 is belt-driven or chain-driven, and the detection cup holder 700 and the light shielding mechanism 800 are respectively disposed on two sides of the transmission member 420, and move synchronously and in opposite directions.
In this embodiment, in the in-process of detecting cup 300 at the reading, detect cup support 700 and shading mechanism 800 motion in opposite directions, shading mechanism 800 carries out the shading to detecting cup 300 when it moves to the coincidence position, detect cup 300 this moment and just move to reading mechanism 500 and carry out the reading, reading mechanism 500 is in the light-resistant environment, do benefit to the precision that improves the detection, simultaneously shading mechanism 800 also can reach when detecting cup 300 and move to reading mechanism 500 and put cup hole 210 department, opposition cup hole 210 shelters from, make the inside whole light-resistant environment that is in of box 200, reach the shading effect equally.
Specifically, the driving element 410 in this embodiment is a stepping motor, and the transmission element 420 is a timing belt.
Preferably, the reading mechanism 500 includes a photon counter 510, a steering engine 520 is disposed on a side surface of the photon counter 510, a lens switching frame 530 is disposed on the steering engine 520, a middle portion of the lens switching frame 530 rotates along with the steering engine 520, an optical filter 540 is disposed at one end of the lens switching frame 530, and a baffle is disposed at the other end of the lens switching frame 530.
In this embodiment, the reading mechanism 500 includes a photon counter 510, a steering engine 520 and a lens switching frame 530, the lens switching frame 530 can rotate under the control of the steering engine 520, and the end with the optical filter 540 or the closed end is rotated to the position of the photon counter 510, so that when the reading mechanism is not used, the photon counter 510 can be closed to avoid light, and damage is avoided; in the using process, one end with the optical filter 540 can be rotated to the position of the photon counter 510, and the detection performance of the instrument can be improved by matching with the optical filters 540 with different multiplying powers.
Preferably, the lower portion of the detection cup holder 700 is connected to the driving mechanism 400, the bottom of the detection cup holder 700 is connected to the case 200 through a slider and a guide rail, the upper portion of the detection cup holder 700 is provided with the cup placing hole 710, and one side of the cup placing hole 710 is provided with the cup throwing groove 720.
Further preferably, a guide bar 230 is arranged on the inner side wall of the box body 200, one side of the detection cup support 700, which is provided with the cup throwing groove 720, is clamped on the guide bar 230, and the guide bar 230 is horizontally arranged at the upper part of the reading mechanism 500 and is stopped at the cup throwing mechanism 600.
In this embodiment, the guide rail and the slider provided at the bottom of the detection cup holder 700 can provide support, which facilitates the stable movement of the detection cup holder 700; the cup placing hole 710 is formed in the detection cup support 700, and the cup throwing groove 720 is formed in the side face of the cup placing hole 710, so that the detection cup 300 can be conveniently discarded; the guide strip 230 arranged on the box body 200 can laterally support the detection cup 300 in the cup placing hole 710, so that the detection cup 300 is prevented from moving during reading, the reading mechanism 500 is facilitated to read, and the guide strip 230 is stopped at the cup throwing mechanism 600, so that the detection cup 300 can be conveniently withdrawn from the cup throwing groove 720.
Preferably, the cup throwing mechanism 600 includes a cup throwing guide block 610 connected to the housing, the cup throwing guide block 610 is provided with a slope corresponding to a portion of the detection cup 300 extending out of the cup placing hole 710, and the housing 200 is further provided with a disposal channel 620 corresponding to the cup throwing guide block 610.
Further preferably, the side wall of the box 200 is provided with an in-position detection sensor 240, and the side surface of the detection cup holder 700 is provided with a detection stop piece 730 corresponding to the side surface.
In this embodiment, the cup throwing mechanism 600 includes a cup throwing guide block 610, an inclined plane is disposed on the cup throwing guide block 610, when the detection cup support 700 moves to the cup throwing mechanism 600, the cup throwing groove 720 on the detection cup support 700 leaves the guide strip 230, the part of the detection cup 300 extending out of the detection cup support 700 moves along the inclined plane under the action of the cup throwing guide block 610 and exits the cup placing hole 710 through the cup throwing groove 720, and finally enters the discarding channel 620 for discarding; the side blocking pieces 900 are arranged on two sides of the discarding channel 620, so that the detection cup 300 can enter the discarding channel 620; meanwhile, the box body 200 is further provided with an in-place detection sensor 240, when the detection cup holder 700 moves to a certain position, the detection cup 300 is completely withdrawn and the in-place detection sensor 240 is triggered, and the cup throwing action is finished.
Preferably, the lower portion of the light shielding mechanism 800 is connected to the driving mechanism 400, the upper portion of the light shielding mechanism 800 is horizontally provided with a light shielding plate 810, the bottom of the light shielding mechanism 800 is further provided with a roller 820, and the side of the light shielding mechanism 800 is connected to the box 200 through a slider and a guide rail.
The slider, the guide rail and the roller 820 on the light shielding mechanism 800 can provide support to ensure stable movement of the light shielding plate 810.
Example two:
as shown in fig. 10 to 12, a reading device of a chemiluminescence immunoassay analyzer comprises a support leg 100 and a box 200, wherein the box 200 is provided with a cup placing hole 210 and an excitation liquid injection needle 220, the cup placing hole 210 is used for placing a detection cup 300, and the reading device further comprises:
a driving mechanism 400 disposed in the case 200;
a reading mechanism 500 disposed in the case 200 and configured to read the detection cup 300;
the cup throwing mechanism 600 is arranged on the box body 200 and used for throwing away the detected detection cup 300;
a detection cup support 700 connected to the driving mechanism 400 and having two cup placing holes 210, wherein the two detection cups 300 in the cup placing holes 710 may be the same or different, and the excitation liquid injection needle 220 disposed on the box 200 corresponds to the detection object; the light shielding mechanism 800 is connected with the driving mechanism 400, the detection cup bracket 700 reciprocates among the cup placing hole 210, the reading mechanism 500 and the cup throwing mechanism 600 and completes the actions of placing, reading and discarding the detection cup 300, and the light shielding mechanism 800 shields the detection cup when reading;
when the reading mechanism reads the first detection cup 300, the light shielding mechanism 800 moves to the cup opening of the detection cup 300 to shield light; when the reading mechanism 500 reads the second detection cup 300, the light shielding mechanism 800 moves to the cup placing hole 210 to shield light.
According to the reading device of the chemiluminescence immunoassay analyzer, two cup placing holes 710 are formed in a detection cup support 700, detection objects of detection cups in the two cup placing holes 710 can be different, and in the process that a light shielding mechanism 800 and the detection cup support 700 move, the light shielding mechanism 800 shields light of the detection cup 300;
specifically, when the first detection cup 300 reads, the light shielding mechanism 800 moves opposite to the detection cup support 700 and is just located at the cup opening of the first detection cup 300, so as to shield the detection cup; when the second detection cup 300 reads, the shading mechanism 800 continues to move to the cup placing hole 210, the whole inside of the box body 200 is in a light-proof environment, the shading effect is achieved, the two detection cups 300 can be in the light-proof environment during reading, and the detection reading accuracy can be effectively improved; meanwhile, the detection cup support 700 and the shading mechanism 800 can be realized through one driving mechanism 400, and the structure is simple;
when the detection objects in the detection cup 300 are different, the excitation liquid in the excitation liquid injection needle 220 corresponds to the detection objects, the detection objects are not influenced mutually in the detection process, the detection of two different detection objects by the same mechanism can be realized, and the efficiency and the accuracy are improved.
It should be noted that all the directional indicators (such as up, down, left, right, front, and rear … …) in the embodiment of the present invention are only used to explain the relative position relationship between the components, the movement situation, etc. in a specific posture (as shown in the drawing), and if the specific posture is changed, the directional indicator is changed accordingly.
Moreover, descriptions of the present invention as relating to "first," "second," "a," etc. are for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicit ly indicating a number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "connected," "secured," and the like are to be construed broadly, and for example, "secured" may be a fixed connection, a removable connection, or an integral part; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
In addition, the technical solutions in the embodiments of the present invention may be combined with each other, but it must be based on the realization of those skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination of technical solutions should not be considered to exist, and is not within the protection scope of the present invention.
Claims (8)
1. The utility model provides a chemiluminescence immunoassay appearance reading device, includes supporting leg and box, is provided with on the box and puts a hole and arouse liquid injection needle, puts a hole and is used for putting into the detection cup, its characterized in that still includes:
the driving mechanism is arranged in the box body;
the reading mechanism is arranged in the box body and is used for reading the detection cup;
the detection cup support is connected with the driving mechanism and is provided with a cup placing hole, and the cup placing hole is used for placing the detection cup;
the cup throwing mechanism is arranged in the box body and used for throwing the detected detection cup, the cup throwing mechanism comprises a cup throwing guide block connected with the box body, an inclined plane is arranged on the cup throwing guide block and corresponds to the part, extending out of the cup placing hole, of the detection cup, and a throwing channel is further arranged on the box body and corresponds to the position of the cup throwing guide block;
the light shading mechanism is connected with the driving mechanism, the detection cup support reciprocates among the cup placing hole, the reading mechanism and the cup throwing mechanism and completes the actions of placing, reading and throwing the detection cup, the light shading mechanism shades light when detecting the reading of the detection cup, the detection cup support and the light shading mechanism move oppositely in the process of reading the detection cup, and when the detection cup reaches the reading mechanism, the light shading mechanism moves to the cup mouth of the detection cup or the cup placing hole to shade light.
2. The reading device of claim 1, wherein the driving mechanism comprises a driving member and a transmission member, the transmission member is belt-driven or chain-driven, the detection cup holder and the light shielding mechanism are respectively disposed on two sides of the transmission member, and the detection cup holder and the light shielding mechanism move synchronously and in opposite directions.
3. The chemiluminescence immunoassay analyzer reading device of claim 1, wherein the reading mechanism comprises a photon counter, a steering engine is arranged on the side face of the photon counter, a lens switching frame is arranged on the steering engine, the middle part of the lens switching frame rotates along with the steering engine, an optical filter is arranged at one end of the lens switching frame, and a baffle is arranged at the other end of the lens switching frame.
4. The reading device of claim 1, wherein the lower portion of the detection cup holder is connected to the driving mechanism, the bottom of the detection cup holder is connected to the box body through a sliding block and a guide rail, the upper portion of the detection cup holder is provided with the cup placing hole, and one side of the cup placing hole is provided with the cup throwing groove.
5. The reading device of the chemiluminescence immunoassay analyzer of claim 4, wherein the inner side wall of the box body is provided with a guide strip, one side of the detection cup support provided with the cup throwing groove is clamped on the guide strip, and the guide strip is horizontally arranged at the upper part of the reading mechanism and is stopped at the cup throwing mechanism.
6. The reading device of the chemiluminescence immunoassay analyzer of claim 1, wherein the side wall of the box body is provided with an in-position detection sensor, and the side surface of the detection cup support is provided with a detection blocking sheet corresponding to the detection blocking sheet.
7. The reading device of a chemiluminescent immunoassay analyzer according to claim 1, wherein the lower part of the light shielding mechanism is connected with the driving mechanism, the upper part of the light shielding mechanism is horizontally provided with a light shielding plate, the bottom of the light shielding mechanism is also provided with rollers, and the side surface of the light shielding mechanism is connected with the box body through a sliding block and a guide rail.
8. The utility model provides a chemiluminescence immunoassay appearance reading device, includes supporting leg and box, is provided with on the box and puts a hole and arouse liquid injection needle, puts a hole and is used for putting into the detection cup, its characterized in that still includes:
the driving mechanism is arranged in the box body;
the reading mechanism is arranged in the box body and is used for reading the detection cup;
the cup throwing mechanism is arranged on the box body and is used for throwing the detected detection cup;
the detection cup bracket is connected with the driving mechanism and is provided with two cup placing holes, and an excitation liquid injection needle arranged on the box body corresponds to the detection cup;
the light shading mechanism is connected with the driving mechanism, the detection cup support reciprocates among the cup placing hole, the reading mechanism and the cup throwing mechanism and completes the placing, reading and throwing actions of the detection cup, and the light shading mechanism shades the detection cup when the reading of the detection cup is detected;
when the reading mechanism reads the first detection cup, the shading mechanism moves to the cup opening of the detection cup to shade light; when the reading mechanism reads the second detection cup, the shading mechanism moves to the cup placing hole to shade light.
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| CN202111456589.2A CN113865699B (en) | 2021-12-02 | 2021-12-02 | Chemiluminescence immunoassay appearance reading device |
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| CN202111456589.2A CN113865699B (en) | 2021-12-02 | 2021-12-02 | Chemiluminescence immunoassay appearance reading device |
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| CN113865699B true CN113865699B (en) | 2022-03-15 |
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| CN207675772U (en) * | 2018-01-17 | 2018-07-31 | 哈尔滨工业大学（威海） | A kind of measuring device for chemiluminescence immunoassay detection |
| CN112798775B (en) * | 2021-01-13 | 2024-08-16 | 烟台晟锋医疗科技有限责任公司 | Dark box detection system of chemiluminescence immunoassay analyzer |
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Address after: 315040 east area, 4th floor, building 044, 66 Qingyi Road, high tech Zone, Ningbo City, Zhejiang Province Patentee after: Ningbo Haiershi Intelligent Manufacturing Co.,Ltd. Address before: 315040 East, 4th floor, building 044, 66 Qingyi Road, high tech Zone, Ningbo City, Zhejiang Province Patentee before: NINGBO HAIYI BIOTECHNOLOGY CO.,LTD. |
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