CN113304191A - 一种复方紫杉醇冻干粉 - Google Patents

一种复方紫杉醇冻干粉 Download PDF

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CN113304191A
CN113304191A CN202110699482.4A CN202110699482A CN113304191A CN 113304191 A CN113304191 A CN 113304191A CN 202110699482 A CN202110699482 A CN 202110699482A CN 113304191 A CN113304191 A CN 113304191A
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冯遵侠
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Abstract

本发明公开了一种复方紫杉醇冻干粉，所述冻干粉的成分包括紫杉醇、莲子心以及冰叶日中花提取物，将紫杉醇、莲子心以及冰叶日中花提取物通过其液态、颗粒状态混合，混合后冻干成粉，所述紫杉醇的重量为0.4‑0.8g，莲子心的重量为0.1‑0.7g，冰叶日中花提取物的重量为0.1‑0.7g；本发明可以修复各类皮肤病，蛇胆疮、褥疮，皮肤感染炭疽病。

Description

一种复方紫杉醇冻干粉
技术领域
本发明属于护肤产品技术领域，具体涉及一种复方紫杉醇冻干粉。
背景技术
冻干粉的主要功能和作用是，其所含有的营养物质可以有效地用于美容养颜，有效的促进分泌乳酸、脂肪酸，防止皮肤干燥干裂，淡化细纹，促进伤口的愈合，平衡组织细胞的分裂增殖，防止结缔组织增生，防止新生组织纤维化。不同的冻干粉有不同作用和效果，但是目前市面上的冻干粉均不能有效的修复皮肤病，比如蛇胆疮、褥疮，皮肤感染炭疽病，同样的也无法抵抗细胞癌变。
发明内容
本发明的目的是为了更好的修复各类皮肤病，提出一种复方紫杉醇冻干粉。
为了实现上述目的，本发明采用的技术方案如下：
一种复方紫杉醇冻干粉，所述冻干粉的成分包括紫杉醇、莲子心以及冰叶日中花提取物，将紫杉醇、莲子心以及冰叶日中花提取物通过其液态、颗粒状态混合，混合后冻干成粉，所述紫杉醇的重量为0.4-0.8g，莲子心的重量为0.1-0.7g，冰叶日中花提取物的重量为0.1-0.7g。
优选地，所述冻干粉的成分中还增加甘草提取物。
优选地，紫杉醇通过红豆杉树皮中提取。
优选地，采用新鲜的莲子心，乙醇提取，提取液减压浓缩至一定密度后，离心，上清液加碱调pH，低温冷置一定时间后离心，得沉淀，减压干燥，得到莲子心有效部位提取物。
优选地，冰叶日中花提取物制备方法是选取冰叶日中花，将冰叶日中花干燥，干燥过后粉碎，粉碎60-100目，对粉碎后的冰叶日中花提取，得到的提取液后离心去除杂质。
优选地，所述冰叶日中花干燥含水率要少于2%，采用的超声波提取。
一种复方紫杉醇冻干粉的制备方法，所述方法步骤如下：
S1:按照配方称取紫杉醇、莲子心以及冰叶日中花提取物，粉碎混合，过筛50目，得到混合细粒；
S2:向混合细粒中加入80%的乙醇，得到混悬液，自然静置，过滤得到上层液体；
S3:所述上层液体加热分离出乙醇，得到复合物的提液；
S4:得到提液进行浓缩冻干，最后形成冻干粉。
上述技术方案可以得到以下有益效果：
本发明可以修复各类皮肤病，蛇胆疮、褥疮，皮肤感染炭疽病，增加毛细血管张力和弹力，改善微循环，从而达到修复面部的红血丝的作用。
本发明新鲜的莲子心，冻干粉制备发酵提取物，新鲜莲子心含有生物碱可以清热解毒消肿，促进血液循环以及保护心血管杨欣安神，使得皮肤酸碱平衡。
新鲜的莲子提取物含有丰富的黄心树宁碱和硒元素，能够预防人体组织细胞癌变，天然抗癌物质，提高机体免疫力，有效的预防皮肤炎症。
冰叶日中花冻干粉制备不含防腐剂，发酵提取物，冰叶日中花属于中盐碱植物，减缓脑细胞老化，保护皮肤不干燥，含有少量黄铜化合物，是一种高活性天然多酚类化合物，冰叶日中花富含多种氨基酸抗酸化物质等机能，含有多种维生素，低钠盐，抗氧化抗衰老。
红豆杉冻干粉制备不含防腐剂发酵提取物，红豆杉能够释放各种生物碱，是绿色的增压机，红豆杉提取物紫杉醇，紫杉碱，还有双类化合物，这些物质抗癌应用到抗癌利尿消肿，抗衰老，紫杉醇能够激活巨噬细胞，抑制肿癌，坏死受体的减少以及释放，杀伤或抑制肿瘤细胞，紫杉醇可以诱导细胞凋零引起细胞程序性死亡，增强免疫，新陈代谢，新生细胞再生能力强，抗衰老。
具体实施方式
下面对本发明做进一步的说明：
一种复方紫杉醇冻干粉，所述冻干粉的成分包括紫杉醇、莲子心以及冰叶日中花提取物，将紫杉醇、莲子心以及冰叶日中花提取物通过其液态、颗粒状态混合，混合后冻干成粉，所述紫杉醇的重量为0.4-0.8g，莲子心的重量为0.1-0.7g，冰叶日中花提取物的重量为0.1-0.7g。
优选地，所述冻干粉的成分中还增加甘草提取物。
优选地，紫杉醇通过红豆杉树皮中提取。
优选地，采用新鲜的莲子心，乙醇提取，提取液减压浓缩至一定密度后，离心，上清液加碱调pH，低温冷置一定时间后离心，得沉淀，减压干燥，得到莲子心有效部位提取物。
优选地，冰叶日中花提取物制备方法是选取冰叶日中花，将冰叶日中花干燥，干燥过后粉碎，粉碎60-100目，对粉碎后的冰叶日中花提取，得到的提取液后离心去除杂质。
优选地，所述冰叶日中花干燥含水率要少于2%，采用的超声波提取。
一种复方紫杉醇冻干粉的制备方法，所述方法步骤如下：
S1:按照配方称取紫杉醇、莲子心以及冰叶日中花提取物，粉碎混合，过筛50目，得到混合细粒；
S2:向混合细粒中加入80%的乙醇，得到混悬液，自然静置，过滤得到上层液体；
S3:所述上层液体加热分离出乙醇，得到复合物的提液；
S4:得到提液进行浓缩冻干，最后形成冻干粉。
实施例1：
本发明制备的复方紫杉醇冻干粉，其中紫杉醇的重量为0.6g，莲子心的重量为0.15g，冰叶日中花提取物的重量为0.25g，上述三种成分，基于其液态、颗粒形状混合形成冻干粉，实现各个成分之间的效用结合，冻干粉最后形成固体或液体，达到修复各类皮肤病，蛇胆疮、褥疮，皮肤感染炭疽病的目的，同时可以对抗细胞癌。
使用患者A，使用液体的冻干粉，喷涂到患者面部过敏红肿瘙痒处，此处可以很快恢复到原来的皮肤状态。
实施例2：
在实施例1的基础上增加甘草提取物，与上述紫杉醇、莲子心以及冰叶日中花提取物，将红豆杉、莲子心以及冰叶日中花提取物混合，甘草提取物的美白作用主要是通过抑制酪氨酸酶和多巴色素互变酶(TRP-2)的活性、阻碍5,6—二羟基吲哚(DHl)的聚合，以此来阻止黑色素的形成，从而达到美白皮肤的效果。同时使得冻干粉还具有美白的作用。
一种复方紫杉醇冻干粉的制备方法，所述方法步骤如下：
S1:按照配方称取紫杉醇、莲子心以及冰叶日中花提取物，粉碎混合，过筛50目，得到混合细粒；
S2:向混合细粒中加入80%的乙醇，得到混悬液，自然静置，过滤得到上层液体；
S3:所述上层液体加热分离出乙醇，得到复合物的提液；
S4:得到提液进行浓缩冻干，最后形成冻干粉。
以上所述均为本发明的优选实施方式，对于本技术领域的普通技术人员，在不脱离本发明的原理前提下，对本发明的各种等价形式的修改均属于本申请所附权利要求的保护范围。

Claims (7)

1.一种复方紫杉醇冻干粉，其特征在于：所述冻干粉的成分包括紫杉醇、莲子心以及冰叶日中花提取物，将紫杉醇、莲子心以及冰叶日中花提取物通过其液态、颗粒状态混合，混合后冻干成粉，所述紫杉醇的重量为0.4-0.8g，莲子心的重量为0.1-0.7g，冰叶日中花提取物的重量为0.1-0.7g。
2.根据权利要求1所述的一种复方紫杉醇冻干粉，其特征在于：所述冻干粉的成分中还增加甘草提取物。
3.根据权利要求1所述的一种复方紫杉醇冻干粉，其特征在于：紫杉醇通过红豆杉树皮中提取。
4.根据权利要求1所述的一种复方紫杉醇冻干粉，其特征在于：采用新鲜的莲子心，乙醇提取，提取液减压浓缩至一定密度后，离心，上清液加碱调pH，低温冷置一定时间后离心，得沉淀，减压干燥，得到莲子心有效部位提取物。
5.根据权利要求1所述的一种复方紫杉醇冻干粉，其特征在于：冰叶日中花提取物制备方法是选取冰叶日中花，将冰叶日中花干燥，干燥过后粉碎，粉碎60-100目，对粉碎后的冰叶日中花提取，得到的提取液后离心去除杂质。
6.根据权利要求5所述的一种复方紫杉醇冻干粉，其特征在于：所述冰叶日中花干燥含水率要少于2%，采用的超声波提取。
7.根据权利要求1所述的一种复方紫杉醇冻干粉的制备方法，其特征在于：所述方法步骤如下：
S1:按照配方称取紫杉醇、莲子心以及冰叶日中花提取物，粉碎混合，过筛50目，得到混合细粒；
S2:向混合细粒中加入80%的乙醇，得到混悬液，自然静置，过滤得到上层液体；
S3:所述上层液体加热分离出乙醇，得到复合物的提液；
S4:得到提液进行浓缩冻干，最后形成冻干粉。
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US5900367A (en) * 1995-04-29 1999-05-04 Samyang Genex Co., Ltd. Method for purifying taxol from taxus biomass
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