CN113303761B - Artifact eliminating device and artifact eliminating method for OCT - Google Patents

Artifact eliminating device and artifact eliminating method for OCT Download PDF

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Publication number
CN113303761B
CN113303761B CN202110474342.7A CN202110474342A CN113303761B CN 113303761 B CN113303761 B CN 113303761B CN 202110474342 A CN202110474342 A CN 202110474342A CN 113303761 B CN113303761 B CN 113303761B
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Prior art keywords
optical fiber
shaft sleeve
pressing
artifact
inner cavity
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CN113303761A (en
Inventor
字德明
耿科
李百灵
高峻
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Guangzhou Winstar Medical Technology Co ltd
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Guangzhou Winstar Medical Technology Co ltd
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Priority to CN202110474342.7A priority Critical patent/CN113303761B/en
Priority to PCT/CN2021/094705 priority patent/WO2022227143A1/en
Publication of CN113303761A publication Critical patent/CN113303761A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal

Abstract

The invention discloses an artifact eliminating device for OCT, which comprises a shaft sleeve with an inner cavity, an optical fiber penetrating through the inner cavity and a pressing piece fixed on the shaft sleeve; the pressing piece extends into the inner cavity and presses against the side face of the optical fiber to bend the optical fiber. The optical fiber is arranged in the shaft sleeve in a penetrating mode, the pressing part is adopted to press the side face of the optical fiber to bend the optical fiber, stray light transmitted in the optical fiber is filtered, the stray light is prevented from being coupled into an external host machine light path to interfere imaging information, and therefore artifacts are eliminated. The invention also discloses an artifact eliminating method.

Description

Artifact eliminating device and artifact eliminating method for OCT
Technical Field
The invention relates to the technical field of medical instruments, in particular to an artifact removing device and an artifact removing method for OCT.
Background
Optical interference Tomography (OCT) is an Optical imaging technique based on the principle of interference of weak coherent light, which obtains a two-dimensional or three-dimensional structure of biological tissue by detecting back-reflected or scattered signals of weak coherent light emitted by different tissues to an Optical fiber.
The OCT optical scanning probe obtains images through internal optical fiber rotation scanning, and layer-by-layer scanning can be carried out through axial movement of the probe while the optical fiber rotates, so that richer image information can be obtained. However, in the prior art, when the probe is used for imaging, the probe is connected with the host, and at this time, stray light transmitted in the optical fiber is easily coupled into an optical path of an external host, so that imaging information of the host is interfered, and imaging artifacts are easily caused.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention has an object to provide an artifact removing device for OCT, and an artifact removing method, which have the characteristic of removing the artifact.
One of the purposes of the invention is realized by adopting the following technical scheme:
an artifact eliminating device comprises a shaft sleeve with an inner cavity, an optical fiber penetrating through the inner cavity and a pressing piece fixed on the shaft sleeve; the pressing piece extends into the inner cavity and presses against the side face of the optical fiber to bend the optical fiber.
In an alternative embodiment, the curved portion of the optical fiber has a radius of curvature of 10-50 mm.
In an optional embodiment, an observation hole is further formed in a position, opposite to the bent portion of the optical fiber, of the side surface of the shaft sleeve, and the observation hole is communicated with the outside and the inner cavity; the artifact eliminating device is also provided with a sealing plug which can be plugged and unplugged and seals the observation hole in a sealing way.
In an alternative embodiment, the artifact removal device further comprises a loose tube disposed through the lumen; the optical fiber penetrates through the loose tube; the pressing piece is pressed against the loose tube to press the optical fiber.
In an optional embodiment, a channel is formed in the side surface of the shaft sleeve, and the channel is communicated with the outside and the inner cavity; the inner wall of the channel is provided with a first thread; the pressing piece penetrates through the channel, and second threads matched with the first threads in a threaded manner are formed in the outer side face of the pressing piece.
In an optional embodiment, a surface of the pressing part facing away from the inner cavity is provided with an inner hexagonal screw hole.
In an alternative embodiment, the pressing member includes a connecting portion fixedly connected to the sleeve, and a pressing portion extending from the connecting portion toward the end of the optical fiber and gradually narrowing toward the optical fiber.
In an optional embodiment, the pressing portion is conical, or hemispherical.
One of the purposes of the invention is realized by adopting the following technical scheme:
a method of artifact removal comprising the steps of:
movably penetrating the optical fiber into the shaft sleeve; and pressing the side surface of the part of the optical fiber in the shaft sleeve by using a pressing part to bend the optical fiber.
In an alternative embodiment, the radius of curvature of the curved portion of the optical fiber is 10-50 mm.
Compared with the prior art, the invention has the beneficial effects that:
1. the optical fiber is arranged in the shaft sleeve in a penetrating mode, the pressing part is adopted to press the side face of the optical fiber to bend the optical fiber, stray light transmitted in the optical fiber is filtered, the stray light is prevented from being coupled into an external host machine light path to interfere imaging information, and therefore artifacts are eliminated.
2. The radius of curvature of the bent part of the optical fiber is preferably 10-50mm, so that the artifacts can be effectively eliminated, and damage caused by over-pressing can be avoided.
3. The observation hole is formed in the shaft sleeve, so that an operator can conveniently observe the bending degree of the optical fiber, and the sealing plug for sealing and plugging the observation hole is further arranged, so that sundries are prevented from entering the shaft sleeve.
4. According to the invention, the loose tube is arranged, and the optical fiber is arranged in the loose tube in a penetrating manner, so that the optical fiber can be arranged loosely, and the optical fiber is protected from the influence of internal stress and external side pressure.
5. According to the invention, the shaft sleeve and the pressing piece are in threaded connection and match through the first thread and the second thread, so that the shaft sleeve can be rotated to adjust the pressing degree of the pressing piece on the optical fiber, and the optical fiber can be bent to a degree with a better artifact eliminating effect.
6. The pressing part of the pressing part is gradually narrowed relative to the connecting part of the pressing part, so that the action area of the pressing part on the optical fiber is reduced on the basis of ensuring the integral strength, and the optical fiber is easier to bend.
7. The invention prevents the pressing part from forming a tip to cause damage to the optical fiber by the pressing part being conical or hemispherical.
Drawings
FIG. 1 is a schematic structural diagram of an artifact removing apparatus according to the present invention;
FIG. 2 is a cross-sectional view of an artifact removal device of the present invention;
FIG. 3 is an enlarged view of a portion A of FIG. 2 according to the present invention;
FIG. 4 shows the imaging result of scanning a finger with a conventional optical fiber probe that is not bent under pressure;
fig. 5-7 show the imaging results of a probe constructed by the artifact removing device of the present invention scanning a finger.
In FIGS. 1-3: 10. a shaft sleeve; 20. a pressing member; 21. an inner hexagonal screw hole; 22. a connecting portion; 23. a pressing part; 30. an optical fiber; 40. a channel; 50. an observation hole; 60. a sealing plug; 70. and (4) loosening the sleeve.
In FIGS. 4-7: a. a probe sleeve; b. ringing artifacts; c. fixing the interference ring; d. finger tissue.
Detailed Description
The present invention will be further described with reference to the accompanying drawings and the detailed description, and it should be noted that any combination of the embodiments or technical features described below can be used to form a new embodiment without conflict. Except as specifically noted, the materials and equipment used in this example are commercially available. Examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present application and are not to be construed as limiting the present application.
In the description of the present application, it is to be understood that the terms "upper", "lower", "front", "back", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present application and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present application. In the description of the present application, "a plurality" means two or more unless specifically stated otherwise.
In the description of the present application, it should be noted that unless otherwise specifically stated or limited, the terms "connected," "communicating," and "connected" are to be construed broadly, e.g., as meaning a fixed connection, a connection through an intervening medium, a connection between two elements, or an interaction between two elements. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art as appropriate.
The terms "first," "second," and the like in the description and in the claims of the present application and in the above-described drawings are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
The first embodiment is as follows:
referring to fig. 1-3, an artifact removing device includes a shaft sleeve 10 having an inner cavity, an optical fiber 30 inserted into the inner cavity, and a pressing member 20 mounted on the shaft sleeve 10; the pressing member 20 protrudes into the cavity and presses the side of the optical fiber 30 to bend the optical fiber 30, and it is understood that the pressed portion of the optical fiber 30 protrudes outward with respect to the central axis thereof to form a bend.
In practical use, the probe formed by the artifact removing device is connected with an external host, and the probe is used for scanning external finger tissues in a straight state, at this time, fig. 5-7 show imaging results when the optical fiber 30 is subjected to bending processing of different degrees, and as can be directly seen from fig. 4-7, compared with the existing probe which is not subjected to bending processing on the optical fiber 30 in fig. 4, the imaging of fig. 5-7 obviously eliminates artifacts, and as can be seen from the above, the stray light transmitted in the optical fiber 30 can be filtered out through the bent optical fiber 30, so that the stray light is prevented from being coupled into the optical path of the external host to interfere with imaging information, and the artifacts are eliminated.
Referring to fig. 5, which is a scan image of the curvature radius of 55mm at the curved portion of the optical fiber 30, it can be seen from fig. 5 that the artifact is partially eliminated but not completely eliminated compared to fig. 4, and it can be seen that the artifact is not completely eliminated when the curvature radius is too large, i.e., when the bending process of the optical fiber 30 is too small; referring to FIG. 6, the radius of curvature of the curved portion of the fiber 30 is 25mm, and it can be seen from FIG. 6 that the artifacts are completely eliminated; referring to fig. 7, the radius of curvature of the curved portion of the optical fiber 30 is 5mm, and it can be seen from fig. 7 that although the artifact is completely eliminated, the image is entirely dark, it can be seen that, when the radius of curvature of the curved portion of the optical fiber 30 is too small, that is, when the degree of curvature of the optical fiber 30 is too large, the observation of the imaging is affected, and meanwhile, when the optical fiber 30 is too large, the pressing degree of the pressing member 20 on the optical fiber 30 is too large, which easily causes the insertion loss to be too large; therefore, in the preferred embodiment of the present invention, the curvature radius of the curved portion of the optical fiber 30 is 10-50mm, which can ensure better artifact elimination effect, facilitate observation, and avoid over-insertion loss.
In the preferred embodiment of the present invention, the side of the sleeve 10 facing the bent portion of the optical fiber 30 is further provided with an observation hole 50, and the observation hole 50 communicates the outside with the inner cavity, so that an operator can observe the bending degree of the optical fiber 30 conveniently.
In the preferred embodiment of the present invention, the artifact removing device is further provided with a sealing plug 60 which can be plugged and sealed to close the observation hole 50, so as to prevent impurities from entering the interior of the shaft sleeve 10; the opening of the viewing aperture 50 is achieved by pulling out the sealing plug 60.
In the preferred embodiment of the present invention, the artifact removing device further comprises a loose tube 70 disposed through the inner cavity; the optical fiber 30 is inserted into the loose tube 70; the pressing member 20 presses the optical fiber 30 against the loose tube 70; in this manner, the optical fiber 30 may be loosely disposed, protecting the optical fiber 30 from internal stresses and external lateral pressure.
The second embodiment:
the difference from the first embodiment is that the following preferred embodiments are also included:
in a preferred embodiment of the present invention, the shaft sleeve 10 is a coupling, which facilitates connection with an external host through the coupling.
In the preferred embodiment of the present invention, the side of the shaft sleeve 10 is provided with a channel 40, and the channel 40 communicates the outside with the inner cavity; the inner wall of the channel 40 is provided with a first thread; the pressing piece 20 penetrates through the channel 40, and a second thread which is in threaded fit with the first thread is arranged on the outer side face of the pressing piece 20, so that the pressing piece 20 is fixed on the shaft sleeve 10; meanwhile, the pressing member 20 can be adjusted toward or away from the optical fiber 30 by rotating the pressing member 20, so as to adjust the pressing degree of the pressing member to the optical fiber 30, so as to adjust the bending degree of the optical fiber 30, and adjust the bending degree of the optical fiber 30 to a proper range, which is a bending range with a better artifact eliminating effect.
In a preferred embodiment of the present invention, the surface of the pressing member 20 facing away from the inner cavity is provided with an inner hexagonal screw hole 21, at this time, the inner hexagonal screw hole 21 can be inserted by an external screwdriver, so that the pressing member 20 can be driven to rotate by the rotation of the external screwdriver, i.e., the pressing member 20 can be conveniently rotated; of course, the inner hexagonal screw hole 21 may be replaced by an inner octagonal screw hole or an inner triangular screw hole, as long as an external screwdriver can be inserted in a matching manner to form a circumferential relatively fixed relationship, so that the pressing member 20 can be driven to rotate by rotating the external screwdriver.
In the third embodiment:
the difference from the first embodiment is that the following preferred embodiments are also included:
in a preferred embodiment of the present invention, the pressing element 20 includes a connecting portion 22 fixedly connected to the sleeve 10, and a pressing portion 23 extending from the connecting portion 22 toward the end of the optical fiber 30 and gradually narrowing toward the optical fiber 30; it can be understood that the outer diameter of the pressing portion 23 is gradually reduced from one end close to the connecting portion 22 to the other end thereof, so that the acting area of the pressing portion 23 on the optical fiber 30 can be reduced, and thus the bending of the optical fiber 30 can be achieved more quickly.
In the preferred embodiment of the present invention, the pressing portion 23 is conical, or the pressing portion 23 is hemispherical, so that the pressing portion 23 can be prevented from forming a tip toward the end of the optical fiber 30, and the optical fiber 30 can be prevented from being damaged.
In the case of combining the second and third embodiments, the second screw thread is preferably provided on the connecting portion 22.
The fourth embodiment: referring to fig. 1-3, an artifact removal method includes the steps of:
the optical fiber 30 is movably arranged in the shaft sleeve 10 in a penetrating way; pressing the side surface of the part of the optical fiber 30 in the shaft sleeve 10 by using the pressing piece 20 to bend the optical fiber 30; in practical use, the probe formed by the bent optical fiber 30 is connected with an external host, and the probe is used for scanning external finger tissues, at this time, fig. 5-7 are imaging results obtained when the optical fiber 30 is subjected to bending processing of different degrees, and as can be directly seen from fig. 4-7, compared with the existing probe in which the optical fiber 30 is not subjected to bending processing in fig. 4, the imaging in fig. 5-7 obviously eliminates artifacts, and as can be seen from the above, the invention can filter out stray light transmitted in the optical fiber 30 through the bent optical fiber 30, and avoid the stray light from being coupled into the optical path of the external host to interfere with imaging information, thereby eliminating the artifacts.
Referring to fig. 5, which is a scan image of the curvature radius of 55mm at the curved portion of the optical fiber 30, it can be seen from fig. 5 that the artifact is partially eliminated but not completely eliminated compared to fig. 4, and it can be seen that the artifact is not completely eliminated when the curvature radius is too large, i.e., when the bending process of the optical fiber 30 is too small; referring to FIG. 6, the radius of curvature of the curved portion of the fiber 30 is 25mm, and it can be seen from FIG. 6 that the artifacts are completely eliminated; referring to fig. 7, the curvature radius of the curved portion of the optical fiber 30 is 5mm, and it can be seen from fig. 7 that although the artifact is completely eliminated, the image is dark as a whole, and the fixed interference ring is dark and unclear, it can be seen that the curvature radius of the curved portion of the optical fiber 30 is too small, that is, when the bending degree of the optical fiber 30 is too large, the observation of the imaging is affected, and meanwhile, when the bending degree of the optical fiber 30 is too large, the pressing degree of the pressing member 20 on the optical fiber 30 is too large, which easily causes the insertion loss to be too large; therefore, in the preferred embodiment of the present invention, the curvature radius of the curved portion of the optical fiber 30 is 10-50mm, which can ensure better artifact elimination effect, facilitate observation, and avoid over-insertion loss.
In the preferred embodiment of the present invention, a viewing hole 50 is further formed on the side surface of the sleeve 10 facing the bent portion of the optical fiber 30, and the viewing hole 50 communicates the outside with the inner cavity, so that an operator can conveniently view the bending degree of the optical fiber 30.
In the preferred embodiment of the present invention, the sealing plug 60 is further adopted to seal and plug the sealing plug 60 of the observation hole 50, so as to prevent impurities from entering the interior of the shaft sleeve 10; at the same time, the sealing plug 60 can be pulled out and inserted, and the observation hole 50 can be opened by pulling out the sealing plug 60.
In the preferred embodiment of the present invention, a loose tube 70 is inserted into the shaft sleeve 10, the optical fiber 30 is inserted into the loose tube 70, and the pressing member 20 presses the optical fiber 30 against the loose tube 70; in this manner, the optical fiber 30 may be loosely disposed, protecting the optical fiber 30 from internal stresses and external lateral pressure.
In a preferred embodiment of the present invention, the shaft sleeve 10 is a coupling, which facilitates connection with an external host through the coupling.
In the preferred embodiment of the present invention, a channel 40 is formed on the side surface of the shaft sleeve 10, and the channel 40 communicates the outside with the inner cavity; the shaft sleeve 10 and the channel 40 are connected through threads, so that the pressing piece 20 is fixed on the shaft sleeve 10; meanwhile, the pressing member 20 can be adjusted toward or away from the optical fiber 30 by rotating the pressing member 20, so as to adjust the pressing degree of the pressing member to the optical fiber 30, so as to adjust the bending degree of the optical fiber 30, and adjust the bending degree of the optical fiber 30 to a proper range, which is a bending range with a better artifact eliminating effect.
In a preferred embodiment of the present invention, the surface of the pressing member 20 facing away from the inner cavity is provided with an inner hexagonal screw hole 21, at this time, the inner hexagonal screw hole 21 can be inserted by an external screwdriver, so that the pressing member 20 can be driven to rotate by the rotation of the external screwdriver, i.e., the pressing member 20 can be conveniently rotated; of course, the inner hexagonal screw hole 21 may be replaced by an inner octagonal screw hole or an inner triangular screw hole, as long as an external screwdriver can be inserted in a matching manner to form a circumferential relatively fixed relationship, so that the pressing member 20 can be driven to rotate by rotating the external screwdriver.
In a preferred embodiment of the present invention, the pressing element 20 includes a connecting portion 22 fixedly connected to the sleeve 10, and a pressing portion 23 extending from the connecting portion 22 toward the end of the optical fiber 30 and gradually narrowing toward the optical fiber 30; it can be understood that the outer diameter of the pressing portion 23 is gradually reduced from one end close to the connecting portion 22 to the other end thereof, so that the acting area of the pressing portion 23 on the optical fiber 30 can be reduced, and thus the bending of the optical fiber 30 can be achieved more quickly.
In the preferred embodiment of the present invention, the pressing portion 23 is made to be conical, or the pressing portion 23 is made to be hemispherical, so that the pressing portion 23 can be prevented from forming a tip toward the end of the optical fiber 30, and the insertion damage to the optical fiber 30 can be avoided.
While only certain features and embodiments of the application have been illustrated and described, many modifications and changes may occur to those skilled in the art (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, mounting arrangements, use of materials, colors, orientations, etc.) without materially departing from the scope and spirit of the invention in the claims.
Finally, it should be noted that: the above embodiments are only preferred embodiments of the present invention, and the protection scope of the present invention should not be limited thereby, and any insubstantial changes and substitutions made by those skilled in the art based on the present invention are within the protection scope of the present invention.

Claims (8)

1. An artifact removing device for OCT, characterized by: the optical fiber sensor comprises a shaft sleeve with an inner cavity, an optical fiber penetrating through the inner cavity and a pressing piece fixed on the shaft sleeve; the pressing piece extends into the inner cavity and presses the side face of the optical fiber to bend the optical fiber, and the curvature radius of the bent part of the optical fiber is 10-50 mm.
2. The artifact removal apparatus for OCT as claimed in claim 1, wherein: an observation hole is formed in the position, opposite to the optical fiber bending part, of the side face of the shaft sleeve, and the observation hole is communicated with the outside and the inner cavity; the artifact eliminating device is also provided with a sealing plug which can be plugged and unplugged and seals the observation hole in a sealing way.
3. The artifact removal apparatus for OCT as claimed in claim 1, wherein: the artifact eliminating device also comprises a loose sleeve which is arranged in the inner cavity in a penetrating way; the optical fiber penetrates through the loose tube; the pressing piece is pressed against the loose tube to press the optical fiber.
4. The artifact removal device for OCT as claimed in any one of claims 1 to 3, characterized in that: a channel is formed in the side face of the shaft sleeve and is communicated with the outside and the inner cavity; the inner wall of the channel is provided with a first thread; the pressing piece penetrates through the channel, and second threads matched with the first threads in a threaded manner are formed in the outer side face of the pressing piece.
5. The artifact removal apparatus for OCT of claim 4, wherein: and the surface of the pressing part, which is back to the inner cavity, is provided with an inner hexagonal screw hole.
6. The artifact removal device for OCT as claimed in any one of claims 1 to 3, characterized in that: the pressing piece comprises a connecting part fixedly connected with the shaft sleeve and a pressing part which extends towards the end part of the optical fiber from the connecting part to the direction close to the optical fiber and is gradually narrowed.
7. The artifact removal apparatus for OCT of claim 6, wherein: the pressing part is conical or hemispherical.
8. A method of artifact removal, comprising the steps of:
movably penetrating the optical fiber into the shaft sleeve; and pressing the side surface of the part of the optical fiber in the shaft sleeve by using a pressing part to bend the optical fiber, wherein the curvature radius of the bent part of the optical fiber is 10-50 mm.
CN202110474342.7A 2021-04-29 2021-04-29 Artifact eliminating device and artifact eliminating method for OCT Active CN113303761B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202110474342.7A CN113303761B (en) 2021-04-29 2021-04-29 Artifact eliminating device and artifact eliminating method for OCT
PCT/CN2021/094705 WO2022227143A1 (en) 2021-04-29 2021-05-19 Artifact elimination apparatus and artifact elimination method for oct

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Application Number Priority Date Filing Date Title
CN202110474342.7A CN113303761B (en) 2021-04-29 2021-04-29 Artifact eliminating device and artifact eliminating method for OCT

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CN113303761B true CN113303761B (en) 2022-03-18

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JP2008136686A (en) * 2006-12-01 2008-06-19 Pentax Corp Oct probe
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US9655524B2 (en) * 2013-09-13 2017-05-23 Novartis Ag OCT probe with bowing flexor
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JPWO2020095417A1 (en) * 2018-11-08 2021-09-02 国立大学法人福井大学 Optical combiner, light source module, two-dimensional optical scanning device and image projection device

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Application publication date: 20210827

Assignee: Hunan Mealco Medical Technology Co.,Ltd.

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