CN113243988B - Microwave ablation device - Google Patents

Microwave ablation device Download PDF

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Publication number
CN113243988B
CN113243988B CN202110702822.4A CN202110702822A CN113243988B CN 113243988 B CN113243988 B CN 113243988B CN 202110702822 A CN202110702822 A CN 202110702822A CN 113243988 B CN113243988 B CN 113243988B
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microwave
ablation
generator
controller
antenna
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CN113243988A (en
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杨维平
仇思念
李元元
梁作俭
高丽萍
康梁
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Beijing Apollo Saturn Biomedical Technology Co ltd
Beijing Dongfangluo Biomedical Technology Co ltd
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Beijing Apollo Saturn Biomedical Technology Co ltd
Beijing Dongfangluo Biomedical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/1823Generators therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/183Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves characterised by the type of antenna
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/1869Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument interstitially inserted into the body, e.g. needles

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

The invention discloses a microwave ablation device. The microwave ablation device includes: the microwave control system comprises a microwave generator, a controller, a microwave waveguide and a microwave antenna, wherein the controller is electrically connected with the microwave generator; wherein, the microwave generator is used for generating microwaves; a microwave waveguide for transmitting microwaves to the microwave antenna; the microwave antenna is used for receiving microwaves and transmitting a first microwave beam and a second microwave beam which have the same radio frequency and opposite directions so that the first microwave beam and the second microwave beam form a microwave standing wave at a target object; and the controller is used for focusing the antinode of the standing wave of the microwave standing wave on the target part and forming an ablation area. The invention solves the problem that the microwave needle needs to be inserted into the tumor of the human body to cause wound to the human body in the microwave ablation operation, and realizes the effect of reducing the wound to the human body in the ablation process.

Description

Microwave ablation device
Technical Field
The embodiment of the invention relates to a microwave ablation technology, in particular to a microwave ablation device.
Background
Microwave ablation technology is a new technology developed in the last decade, and is a combination of modern medical imaging and microwave technology.
The existing microwave ablation method is to puncture a specially-made microwave needle to the central area of a tumor through skin, form microwave at a certain point of the microwave needle, and enable surrounding molecules to rotate at a high speed and to frictionally heat up through a microwave magnetic field released by the microwave needle, so that tissues are coagulated, dehydrated and necrotized, and the purpose of treatment is achieved.
The microwave needle is inserted into the tumor of a human body, so that great trauma is caused to the human body, and particularly, the great trauma is caused to the tumor ablation in the deep part of the body.
Disclosure of Invention
The invention provides a microwave ablation device, which can reduce the wound generated in the ablation process.
An embodiment of the present invention provides a microwave ablation apparatus, including: the microwave oven comprises a microwave generator, a controller, a microwave waveguide and a microwave antenna, wherein the controller is electrically connected with the microwave generator, and the microwave waveguide is respectively connected with the microwave generator and the microwave antenna; wherein, the first and the second end of the pipe are connected with each other,
the microwave generator is used for generating microwaves;
the microwave waveguide is used for transmitting the microwaves to the microwave antenna;
the microwave antenna is used for receiving the microwaves and sending a first microwave beam and a second microwave beam which have the same radio frequency and opposite directions so that the first microwave beam and the second microwave beam form a microwave standing wave at the target object;
the controller is used for focusing the antinode of the standing wave of the microwave standing wave on a target part and forming an ablation area.
In an optional embodiment of the present invention, the microwave generator comprises a first generator and a second generator, the microwave waveguide comprises a first waveguide and a second waveguide, and the microwave antenna comprises a first antenna and a second antenna, wherein the first generator is connected to the first antenna through the first waveguide, the second generator is connected to the second antenna through the second waveguide, the first antenna is disposed opposite to the second antenna, the first antenna is configured to emit the first microwave beam, and the second antenna is configured to emit the second microwave beam.
In an optional embodiment of the invention, the controller is specifically configured to perform at least one of the following operations:
changing the phase of the microwave standing wave to adjust the position of an antinode of the standing wave;
changing the frequency of the microwave standing wave to adjust the size of the ablation zone;
and regulating and controlling the transmitting power of the microwave generator so as to enable the transmitting power to be in a preset power range.
In an alternative embodiment of the present invention, the varying the phase of the standing microwave wave comprises:
varying a difference in emission time of the first and second microwave beams to vary a phase of the standing microwave wave.
In an alternative embodiment of the present invention, further comprising: the frequency converter is electrically connected with the microwave generator, the alternating current power supply and the controller respectively; wherein, the first and the second end of the pipe are connected with each other,
the controller is further configured to control the frequencies of the first and second microwave beams by adjusting the output frequency of the frequency converter.
In an optional embodiment of the present invention, further comprising a transformer, the transformer being electrically connected to the ac power supply, the microwave generator and the controller, respectively; wherein, the first and the second end of the pipe are connected with each other,
the controller is also used for controlling the output voltage of the transformer so as to enable the transmitting power of the microwave generator to be within a preset power range.
In an alternative embodiment of the present invention, further comprising: power sensors respectively connected to the magnetron of the microwave generator and the controller, wherein,
the power sensor is used for monitoring the transmitting power of the microwave generator and feeding the monitored transmitting power back to the controller.
In an alternative embodiment of the present invention, further comprising: the temperature monitoring module is connected with the controller; wherein the content of the first and second substances,
the temperature monitoring module is used for monitoring the ablation temperature of the ablation zone and feeding the monitored ablation temperature back to the controller;
the controller is used for regulating and controlling the ablation temperature if the ablation temperature is detected to be higher than a preset temperature range, so that the ablation temperature is in the preset temperature range.
In an alternative embodiment of the invention, the temperature monitoring module comprises an nmr instrument electrically connected to the controller, wherein,
the nuclear magnetic resonance spectrometer is used for scanning the ablation temperature of the ablation area in real time;
the controller is specifically used for acquiring the ablation temperature of the ablation area scanned by the nuclear magnetic resonance spectrometer in real time.
In an alternative embodiment of the invention, a beam limiter is connected to an end of the microwave antenna facing away from the microwave waveguide.
The microwave is generated by a microwave generator, then transmitted to a microwave antenna by a microwave waveguide, and then transmitted by the microwave antenna to form a first microwave beam and a second microwave beam which have the same frequency and opposite directions so as to form a microwave standing wave at the target object, and finally, a standing wave antinode of the microwave standing wave is focused on a target part by a controller to form an ablation area. The principle that two beams of reverse microwaves form standing waves is utilized, an ablation area is formed at a target position in a human body, and high temperature cannot be formed at other positions, so that the purpose of local ablation is achieved. The microwave needle does not need to be used for puncturing into the human body, the invasive microwave ablation operation is changed into the non-invasive microwave ablation operation, the problem that the human body is wounded due to the fact that the microwave needle needs to be inserted into the tumor of the human body in the microwave ablation operation is solved, and the effect of reducing the wound of the human body in the ablation process is achieved.
Drawings
Fig. 1 is a schematic structural view of a microwave ablation device provided in one embodiment of the present invention;
FIG. 2 is a waveform diagram of a microwave standing wave in a sine wave according to a first embodiment of the present invention;
FIG. 3 is a schematic diagram of the temperature distribution of the standing microwave wave of FIG. 2;
FIG. 4 is a waveform diagram of a microwave standing wave in a triangular wave according to a first embodiment of the present invention;
FIG. 5 is a schematic diagram of the temperature distribution of the standing microwave wave of FIG. 4;
fig. 6 is an ablation schematic view of a microwave ablation device provided in a first embodiment of the present invention;
fig. 7 is a schematic structural diagram of a microwave ablation device according to a second embodiment of the present invention.
1. A microwave generator; 101. a first generator; 102. a second generator; 2. a microwave waveguide; 3. a microwave antenna; 4. a controller; 5. a frequency converter; 6. a transformer; 7. an alternating current power supply; 8. a power sensor; 9. a temperature monitoring module; 10. a beam limiter; 11. an ablation zone; 12. a first microwave beam; 13. a second microwave beam; 14. and (5) standing microwave waves.
Detailed Description
The present invention will be described in further detail with reference to the drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not to be construed as limiting the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.
Example one
Fig. 1 is a schematic structural diagram of a microwave ablation device provided in an embodiment of the present invention. As shown in fig. 1, an embodiment of the present invention provides a microwave ablation device including: the microwave oven comprises a microwave generator 1, a controller 4, a microwave waveguide 2 and a microwave antenna 3, wherein the controller 4 is electrically connected with the microwave generator 1, and the microwave waveguide 2 is respectively connected with the microwave generator 1 and the microwave antenna 3. Wherein:
a microwave generator 1 for generating microwaves.
Specifically, the microwave generator 1 generally includes a magnetron (not shown), which is an electric vacuum device for generating microwave energy, and the microwave generator 1 generates microwaves through the included magnetron.
A microwave waveguide 2 for transmitting microwaves to a microwave antenna 3.
Specifically, since the microwave frequency is very high, and generally operates in a centimeter wave or millimeter wave band, a great loss is generated by using a common cable or wire for transmission, a metal pipeline with a rectangular or circular cross section is used for feeding the microwave, and the metal pipeline is called as a microwave waveguide 2, and the microwave waveguide 2 is connected with a microwave generator 1 and a microwave antenna 3 respectively, so that the microwave can be transmitted to the microwave antenna 3.
The microwave antenna 3 is used for receiving microwaves and transmitting a first microwave beam 12 and a second microwave beam 13 with the same frequency and opposite directions, so that the first microwave beam 12 and the second microwave beam 13 form a microwave standing wave 14 at the target object.
The microwave antenna 3 refers to a transmitting or receiving antenna operating in the wave bands of millimeter waves, centimeter waves, millimeter waves and the like. A wave oscillates in time but its peak amplitude distribution does not move with space, and is called a standing wave. The position of the standing wave where the amplitude is the smallest is called a node, and the position where the amplitude is the largest is called an antinode. Standing waves may occur as a result of movement of the medium in the opposite direction to the wave, or as a result of the superposition of two traveling waves propagating in opposite directions. The target object is an object requiring ablation, such as a human body.
The temperature distribution conditions corresponding to different microwave waveforms are often different. In the embodiment of the present invention, the specific waveform of the microwave is not limited. The waveform of the microwave can be set or adjusted according to actual requirements. Illustratively, the microwave waveform may include a sine wave, a triangular wave, a square wave, and the like.
As shown in fig. 2, taking the microwave waveform as a sine wave as an example, the first microwave beam 12 and the second microwave beam 13 form a microwave standing wave 14, and the amplitude of the antinode of the microwave standing wave 14 is greater than the amplitude of the peaks of the first microwave beam 12 and the second microwave beam 13. The temperature profile of the microwave standing wave 14 at this time is shown in fig. 3.
In addition, taking the microwave waveform as a triangular wave as an example, as shown in fig. 4, fig. 4 is a waveform diagram of a microwave standing wave, and when the microwave standing wave is a triangular wave, a temperature distribution diagram of the microwave standing wave is shown in fig. 5.
Wherein, the antinode of the standing wave: refers to a point, line or plane in the standing wave field where the amplitude of some physical quantity describing the sound field characteristics is maximum. As shown in fig. 3 or 5, the antinode of the standing wave is the highest temperature, and the node is the lowest temperature.
And a controller 4 for focusing an antinode of the standing microwave wave 14 on the target site and forming the ablation region 11.
Specifically, the ablation region 11 refers to a region where the ablation temperature is reached, and is reflected in the waveform diagram of the microwave standing wave 14 to indicate a partial region around an anti-node in addition to the anti-node. The target site may be a tumor site, a thyroid nodule site, or the like, and is not particularly limited as long as it is a site to be ablated.
Further, the microwave generator 1 includes a first generator 101 and a second generator 102, the microwave waveguide 2 includes a first waveguide and a second waveguide, and the microwave antenna 3 includes a first antenna and a second antenna, where the first generator 101 is connected to the first antenna through the first waveguide, the second generator 102 is connected to the second antenna through the second waveguide, the first antenna and the second antenna are disposed opposite to each other, the first antenna is configured to emit the first microwave beam 12, and the second antenna is configured to emit the second microwave beam 13.
The microwave energy and the frequency emitted by the first generator 101 and the second generator 102 are the same, finally the frequency of the first microwave beam 12 and the frequency of the second microwave beam 13 emitted by the first antenna and the second antenna are the same, and the first microwave beam 12 and the second microwave beam 13 are opposite because the first antenna and the second antenna are oppositely arranged.
Fig. 6 is an ablation schematic diagram of a microwave ablation device according to a first embodiment of the present invention, as shown in fig. 6, a first generator 101 emits a first microwave beam 12 to a target site through a first antenna (not shown in fig. 6), a second generator 102 emits a second microwave beam 13 to the target site through a second antenna (not shown in fig. 6), and then the first microwave beam 12 and the second microwave beam 13 form a microwave standing wave 14 (not shown in fig. 6) and an ablation zone 11 at the target site, so as to perform in vitro ablation on the target site.
Since the first generator 101 emits the first microwave beam 12 through the first antenna and the second generator 102 emits the second microwave beam 13 through the second antenna, the time difference between the emission of the first microwave beam 12 and the emission of the second microwave beam 13 can be conveniently controlled by controlling the time when the first generator 101 and the second generator 102 emit microwaves, and the phase of the formed microwave standing wave 14 can be conveniently adjusted.
According to the technical scheme of the embodiment, microwaves are generated by a microwave generator 1, then are transmitted to a microwave antenna 3 through a microwave waveguide 2, then a first microwave beam 12 and a second microwave beam 13 which have the same frequency and opposite directions are emitted through the microwave antenna 3, so that a microwave standing wave 14 is formed at a target object by the first microwave beam 12 and the second microwave beam 13, and finally a standing wave antinode of the microwave standing wave 14 is focused at the target part through a controller 4 to form an ablation area 11. By utilizing the principle that two beams of reverse microwaves form standing waves, an ablation zone 11 is formed at a target part in a human body, and high temperature cannot be formed at other positions, so that the purpose of local ablation is achieved. The microwave needle does not need to be used for puncturing into the human body, the invasive microwave ablation operation is changed into the non-invasive microwave ablation operation, the problem that the human body is wounded due to the fact that the microwave needle needs to be inserted into the tumor of the human body in the microwave ablation operation is solved, and the effect of reducing the wound of the human body in the ablation process is achieved.
Example two
Fig. 7 is a schematic structural diagram of a microwave ablation device according to a second embodiment of the present invention, which is based on the first embodiment, and the explanation of the same or corresponding devices and terms as the first embodiment is omitted in this embodiment for brevity.
On the basis of the foregoing embodiment, the controller 4 of the present embodiment is specifically configured to perform at least one of the following operations:
the phase of the microwave standing wave 14 is changed to adjust the position of the antinode of the standing wave.
The frequency of the standing microwave wave 14 is varied to adjust the size of the ablation region 11.
The transmission power of the microwave generator 1 is regulated so that the transmission power is in a preset power range.
Wherein the standing microwave wave 14 moves exactly one wavelength when the phase of the standing microwave wave 14 changes 360 degrees. By changing the phase of the microwave standing wave 14, the position of the antinode of the standing wave can be adjusted, and thus the position of the antinode can be adjusted to the target site, and ablation of the target site can be realized.
The wavelength of the microwave standing wave 14 is inversely proportional to the frequency, i.e., λ = u/f, so the lower the frequency, the longer the wavelength, and the distance between two adjacent antinodes is equal to the wavelength. The microwave antinode indicates the highest temperature, and the ablation region 11 indicates a region with a temperature higher than a preset value, and is reflected in the waveform diagram to indicate a partial region around the antinode in addition to the antinode, so that the longer the wavelength is, the larger the heating region is, and the larger the size of the ablation region 11 is. By adjusting the frequency of the standing microwave wave 14, the dimensions of the ablation region 11 can be adjusted.
Specifically, under the condition that other conditions are not changed, the higher the transmitting power of the microwave generator 1 is, the higher the energy of the emitted microwave beam is, the higher the corresponding temperature at the antinode of the corresponding microwave standing wave 14 is, and the higher the temperature of the ablation region 11 is. In order to ensure that the temperature of the ablation zone 11 is in the preset power range, the emission power of the microwave generator 1 is also in a specific range, and the emission power of the microwave generator 1 is controlled to be in the preset power range, so that the temperature of the ablation zone 11 is conveniently controlled to be in the specific range.
It is understood that, in the embodiment of the present invention, the preset power range of the transmission power may be set according to actual requirements, for example, the power range may be preset based on tissue parameters of the target region, and is not limited specifically herein.
On the basis of the above embodiment, the changing the phase of the standing microwave wave 14 may specifically include:
the difference in emission time of the first and second microwave beams 12 and 13 is varied to vary the phase of the standing microwave wave 14.
Since the microwave standing wave 14 is formed by the first microwave beam 12 and the microwave beam, when the emission time difference of the first microwave beam 12 and the second microwave beam 13 is changed, the phase of the microwave standing wave 14 is also changed.
Referring to fig. 4, on the basis of the above embodiment, the microwave ablation apparatus of the present embodiment further includes: the frequency converter 5 is electrically connected with the microwave generator 1, the alternating current power supply 7 and the controller 4 respectively; wherein:
the controller 4 is further configured to control the frequencies of the first microwave beam 12 and the second microwave beam 13 by adjusting the output frequency of the frequency converter 5.
The Variable-frequency Drive (VFD) is a power control device that applies frequency conversion technology and microelectronics technology to control an ac motor by changing the frequency of the operating power supply of the motor. By electrically connecting the frequency converter 5 to the microwave generator 1, the ac power supply 7 and the controller 4, the frequency of the first microwave beam 12 and the second microwave beam 13 emitted by the microwave generator 1 via the microwave antenna 3 can be changed when the output frequency of the frequency converter 5 is changed. Since the standing microwave wave 14 is formed by the first microwave beam 12 and the second microwave beam 13, when the frequencies of the first microwave beam 12 and the second microwave beam 13 are changed, the frequency of the standing microwave wave 14 is changed accordingly, so that the frequency of the standing microwave wave 14 can be changed by adjusting the frequency converter 5.
When the microwave generator 1 comprises a first generator 101 and a second generator 102, it can be electrically connected to both the first generator 101 and the second generator 102 by means of a frequency converter 5 to simultaneously adjust the frequency of the microwaves emitted by the first generator 101 and the second generator 102, so as to vary the frequency of the first microwave beam 12 and the second microwave beam 13. It is also possible to electrically connect the first generator 101 and the second generator 102 by means of two frequency converters 5, one frequency converter 5 controlling the frequency of the microwaves emitted by the first generator 101 and the other frequency converter 5 controlling the frequency of the second generator 102, so that the frequencies of the first microwave beam 12 and the second microwave beam 13 are changed. The number of frequency converters 5 is not limited here, as long as the microwave frequency of the microwave beam emitted by the microwave generator 1 via the microwave antenna 3 can be regulated.
On the basis of the above embodiments, the microwave ablation apparatus of the present embodiment further includes a transformer 6, and the transformer 6 is electrically connected to the ac power supply 7, the microwave generator 1, and the controller 4, respectively; wherein:
and the controller 4 is also used for controlling the output voltage of the transformer 6 so that the transmitting power of the microwave generator 1 is in a preset power range.
The Transformer 6 (Transformer) is a device that changes an alternating voltage by using the principle of electromagnetic induction, and its main components are a primary coil, a secondary coil, and an iron core (magnetic core). The main functions are as follows: voltage transformation, current transformation, impedance transformation, isolation, voltage stabilization, and the like.
Since the transformer 6 is electrically connected to the microwave generator 1, when the output voltage of the transformer 6 is changed, the transmitting power of the microwave generator 1 is also changed accordingly. The output voltage of the transformer 6 is controlled to make the transmitting power of the microwave generator 1 within a preset power range.
On the basis of the above embodiment, the microwave ablation apparatus of the present embodiment further includes: a power sensor 8 connected to the magnetron of the microwave generator 1 and to the controller 4, respectively, wherein:
and the power sensor 8 is used for monitoring the transmitting power of the microwave generator 1 and feeding the detected transmitting power back to the controller 4.
The power sensor 8 is a dual-function meter that can measure both active/reactive power and active/reactive power. The microwaves of the microwave generator 1 are mainly generated by the magnetron thereon, and the power sensor 8 can conveniently detect the emission power of the microwave generator 1 by connecting the power sensor 8 with the magnetron of the microwave generator 1.
Under other conditions, the higher the transmitting power of the microwave generator 1 is, the higher the energy of the first microwave beam 12 and the second microwave beam 13 is, the higher the temperature corresponding to the antinode of the corresponding microwave standing wave 14 is, and the higher the temperature of the ablation region 11 is. In order to make the temperature of the ablation zone 11 within the preset temperature range and the emission power of the microwave generator 1 within a specific range, the emission power of the microwave generator 1 is monitored by the power sensor 8, and then the emission power of the microwave generator 1 is changed by the transformer 6, so that the emission power of the microwave generator 1 can be within the preset power range.
On the basis of the above embodiment, the microwave ablation device of the present embodiment further includes: a temperature monitoring module 9 connected with the controller 4; wherein:
and the temperature monitoring module 9 is used for monitoring the ablation temperature of the ablation zone 11 and feeding the monitored ablation temperature back to the controller 4.
And the controller 4 is used for regulating and controlling the ablation temperature if the ablation temperature is detected to be higher than the preset temperature range, so that the ablation temperature is in the preset temperature range.
The ablation temperature has a preset temperature range, and the ablation effect cannot be well achieved when the ablation temperature is too high or too low. By monitoring the ablation temperature of the ablation zone 11 and regulating and controlling when the ablation temperature is not in the preset temperature range, the ablation temperature can be in the preset temperature range, and a better ablation effect is achieved. The temperature monitoring module 9 is a component capable of acquiring the internal temperature in vitro, such as a nuclear magnetic resonance apparatus, and is not particularly limited as long as it has a function of acquiring the internal temperature in vitro.
The control of the ablation temperature can be realized by controlling the output voltage of the transformer 6 in the above technical scheme, and the output voltage of the transformer 6 is changed to change the emission power of the microwave generator 1, so as to change the ablation temperature of the ablation zone 11.
On the basis of the above embodiment, the temperature monitoring module 9 includes an nmr instrument electrically connected to the controller 4, wherein:
the nuclear magnetic resonance spectrometer is used for scanning the ablation temperature of the ablation zone 11 in real time and feeding the ablation temperature back to the controller 4.
Of course, the ablation temperature of the ablation region 11 scanned by the nmr may also be acquired by the controller 4 in real time.
Specifically, magnetic Resonance Imaging (MRI) is also known as Magnetic Resonance Imaging (MRI). The principle is that a human body is placed in a special magnetic field, and hydrogen atomic nuclei in the human body are excited by radio frequency pulses to cause the hydrogen atomic nuclei to resonate and absorb energy. After stopping the radio frequency pulse, the hydrogen nucleus emits radio signals according to specific frequency, releases the absorbed energy, is recorded by a receiver outside the body, and is processed by an electronic computer to obtain an image. Therefore, the temperature in the human body can be obtained by scanning the nuclear magnetic resonance spectrometer outside the human body.
The ablation temperature of the ablation region 11 can be obtained by a nuclear magnetic resonance apparatus during use, and the controller 4 can obtain the ablation temperature of the ablation region 11 scanned by the nuclear magnetic resonance apparatus by electrically connecting the nuclear magnetic resonance apparatus with the controller 4.
On the basis of the above-described embodiment, optionally, a beam limiter 10 is connected to an end of the microwave antenna 3 facing away from the microwave waveguide 2.
Specifically, the beam limiter 10 is an optical device installed in front of the emitting end of the microwave antenna 3, and can control the width of the microwave beam emitted by the microwave antenna 3 along the axial direction of the ablation part, so that the projection range of the microwave beam can be reduced as much as possible on the premise that the microwave beam can meet the focusing requirement, and the beam limiter can absorb some scattered rays and improve the definition of the microwave beam.
According to the technical scheme of the embodiment, the phase of the microwave standing wave 14 is changed by changing the emission time difference between the first microwave beam 12 and the second microwave beam 13, so that the position of the antinode of the standing wave is adjusted, and the position of the antinode can be conveniently adjusted to a target part to realize ablation of the target part. Meanwhile, the transmitting power of the microwave generator 1 can be monitored through the power sensor 8, and then the transmitting power of the microwave generator 1 is changed through the transformer 6, so that the transmitting power of the microwave generator 1 can be in a preset power range. Meanwhile, the frequency of the first microwave beam 12 and the second microwave beam 13 can be changed by controlling the frequency converter 5, so that the size of the ablation area 11 can be changed, and the size of the ablation area 11 can be controlled within a preset size. And finally, the ablation temperature of the ablation zone 11 can be scanned through a nuclear magnetic resonance spectrometer, the ablation temperature is further obtained through the controller 4, and the ablation temperature is regulated and controlled when being higher than a preset temperature range, so that the ablation temperature is in the preset temperature range. The problem of poor ablation effect caused by the fact that ablation temperature, the size of an ablation area 11 and the transmitting power of a microwave generator 1 are difficult to control within a preset power range in a microwave ablation operation is solved, and the effect that the ablation temperature, the size of the ablation area 11 and the transmitting power of the microwave generator 1 are controlled within the preset power range to enable the ablation effect to be good is achieved.
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments illustrated herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.

Claims (8)

1. A microwave ablation device, comprising: the microwave oven comprises a microwave generator (1), a controller (4), a microwave waveguide (2) and a microwave antenna (3), wherein the controller (4) is electrically connected with the microwave generator (1), and the microwave waveguide (2) is respectively connected with the microwave generator (1) and the microwave antenna (3); wherein the content of the first and second substances,
the microwave generator (1) is used for generating microwaves;
-said microwave waveguide (2) for transmitting said microwaves to said microwave antenna (3);
the microwave antenna (3) is used for receiving the microwaves and transmitting a first microwave beam (12) and a second microwave beam (13) which have the same radio frequency and opposite directions, so that the first microwave beam (12) and the second microwave beam (13) form a microwave standing wave (14) at a target object;
the controller (4) is used for focusing an antinode of the microwave standing wave (14) on a target part and forming an ablation area (11);
the controller (4) is further specifically configured to vary the phase of the microwave standing wave (14) to adjust the position of the antinode of the standing wave;
said varying the phase of the standing microwave wave (14) comprises:
-varying the difference in emission time of the first (12) and second (13) microwave beams to vary the phase of the standing microwave wave (14);
the microwave ablation device also comprises a temperature monitoring module (9) connected with the controller (4); wherein the content of the first and second substances,
the temperature monitoring module (9) is used for monitoring the ablation temperature of the ablation zone (11) and feeding back the monitored ablation temperature to the controller (4);
the controller (4) is used for regulating and controlling the ablation temperature if the ablation temperature is detected to be higher than a preset temperature range, so that the ablation temperature is in the preset temperature range.
2. Microwave ablation device according to claim 1, characterized in that the microwave generator (1) comprises a first generator (101) and a second generator (102), the microwave waveguide (2) comprises a first waveguide and a second waveguide, the microwave antenna (3) comprises a first antenna and a second antenna, wherein the first generator (101) is connected with the first antenna through the first waveguide, the second generator (102) is connected with the second antenna through the second waveguide, the first antenna is arranged opposite to the second antenna, the first antenna is used for emitting the first microwave beam (12), and the second antenna is used for emitting the second microwave beam (13).
3. Microwave ablation device according to claim 1, wherein the controller (4) is particularly adapted to perform at least one of the following operations:
-varying the frequency of the standing microwave wave (14) to adjust the size of the ablation zone (11);
and regulating and controlling the transmitting power of the microwave generator (1) so as to enable the transmitting power to be in a preset power range.
4. A microwave ablation device according to claim 3 further comprising: the microwave generator comprises a frequency converter (5) and an alternating current power supply (7), wherein the frequency converter (5) is electrically connected with the microwave generator (1), the alternating current power supply (7) and the controller (4) respectively; wherein, the first and the second end of the pipe are connected with each other,
the controller (4) is further configured to control the frequency of the first and second microwave beams (12, 13) by adjusting the output frequency of the frequency converter (5).
5. A microwave ablation device according to claim 4, further comprising a transformer (6), the transformer (6) being electrically connected to the AC power source (7), the microwave generator (1) and the controller (4), respectively; wherein the content of the first and second substances,
the controller (4) is also used for controlling the output voltage of the transformer (6) so as to enable the transmitting power of the microwave generator (1) to be within a preset power range.
6. A microwave ablation device according to claim 3 further comprising: a power sensor (8) connected to the magnetron of the microwave generator (1) and to the controller (4), respectively, wherein,
the power sensor (8) is used for monitoring the transmitting power of the microwave generator (1) and feeding the monitored transmitting power back to the controller (4).
7. Microwave ablation device according to claim 1, characterized in that the temperature monitoring module (9) comprises an NMR spectrometer, which NMR spectrometer is electrically connected to the controller (4), wherein,
the nuclear magnetic resonance apparatus is used for scanning the ablation temperature of the ablation area (11) in real time and feeding back the ablation temperature to the controller (4).
8. A microwave ablation device according to claim 1, characterized in that a beam limiter (10) is connected to the end of the microwave antenna (3) facing away from the microwave waveguide (2).
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