CN113234548A - Tooth socket cleaning solution and preparation method thereof - Google Patents
Tooth socket cleaning solution and preparation method thereof Download PDFInfo
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- CN113234548A CN113234548A CN202110545970.XA CN202110545970A CN113234548A CN 113234548 A CN113234548 A CN 113234548A CN 202110545970 A CN202110545970 A CN 202110545970A CN 113234548 A CN113234548 A CN 113234548A
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- cleaning solution
- tooth socket
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- 238000004140 cleaning Methods 0.000 title claims abstract description 50
- 210000003781 tooth socket Anatomy 0.000 title claims abstract description 44
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 32
- 239000004094 surface-active agent Substances 0.000 claims abstract description 20
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims abstract description 13
- 108700004121 sarkosyl Proteins 0.000 claims abstract description 12
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- IXOCGRPBILEGOX-UHFFFAOYSA-N 3-[3-(dodecanoylamino)propyl-dimethylazaniumyl]-2-hydroxypropane-1-sulfonate Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(O)CS([O-])(=O)=O IXOCGRPBILEGOX-UHFFFAOYSA-N 0.000 claims abstract description 10
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000003599 detergent Substances 0.000 claims abstract description 9
- 239000001301 oxygen Substances 0.000 claims abstract description 9
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 9
- 239000003755 preservative agent Substances 0.000 claims abstract description 9
- 230000002335 preservative effect Effects 0.000 claims abstract description 9
- 235000006679 Mentha X verticillata Nutrition 0.000 claims abstract description 8
- 235000002899 Mentha suaveolens Nutrition 0.000 claims abstract description 8
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims abstract description 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 30
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 14
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 claims description 14
- 239000006260 foam Substances 0.000 claims description 11
- 239000004088 foaming agent Substances 0.000 claims description 10
- 239000003381 stabilizer Substances 0.000 claims description 10
- -1 alkyl glycoside Chemical class 0.000 claims description 8
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 7
- 239000003240 coconut oil Substances 0.000 claims description 6
- 235000019864 coconut oil Nutrition 0.000 claims description 6
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 5
- 241000196324 Embryophyta Species 0.000 claims description 5
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 claims description 5
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 5
- 239000004006 olive oil Substances 0.000 claims description 5
- 235000008390 olive oil Nutrition 0.000 claims description 5
- GSWAOPJLTADLTN-UHFFFAOYSA-N oxidanimine Chemical compound [O-][NH3+] GSWAOPJLTADLTN-UHFFFAOYSA-N 0.000 claims description 5
- 235000019482 Palm oil Nutrition 0.000 claims description 4
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 4
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 4
- 150000001413 amino acids Chemical class 0.000 claims description 4
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 claims description 4
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 claims description 4
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 claims description 4
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims description 4
- 229930182470 glycoside Natural products 0.000 claims description 4
- 239000002540 palm oil Substances 0.000 claims description 4
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims description 4
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 claims description 4
- 229960003415 propylparaben Drugs 0.000 claims description 4
- 235000013311 vegetables Nutrition 0.000 claims description 4
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 3
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 3
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 2
- 239000004711 α-olefin Substances 0.000 claims description 2
- 150000002191 fatty alcohols Chemical class 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 abstract description 6
- 241000894006 Bacteria Species 0.000 abstract description 3
- 239000000126 substance Substances 0.000 abstract description 2
- 239000000243 solution Substances 0.000 description 32
- 235000011187 glycerol Nutrition 0.000 description 10
- 241000588724 Escherichia coli Species 0.000 description 6
- 230000005764 inhibitory process Effects 0.000 description 6
- 239000011259 mixed solution Substances 0.000 description 6
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 230000003796 beauty Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000005034 decoration Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/94—Mixtures with anionic, cationic or non-ionic compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2093—Esters; Carbonates
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/34—Organic compounds containing sulfur
- C11D3/349—Organic compounds containing sulfur additionally containing nitrogen atoms, e.g. nitro, nitroso, amino, imino, nitrilo, nitrile groups containing compounds or their derivatives or thio urea
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/39—Organic or inorganic per-compounds
- C11D3/3942—Inorganic per-compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/39—Organic or inorganic per-compounds
- C11D3/3945—Organic per-compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/39—Organic or inorganic per-compounds
- C11D3/3947—Liquid compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/04—Carboxylic acids or salts thereof
- C11D1/10—Amino carboxylic acids; Imino carboxylic acids; Fatty acid condensates thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
- C11D1/14—Sulfonic acids or sulfuric acid esters; Salts thereof derived from aliphatic hydrocarbons or mono-alcohols
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
- C11D1/14—Sulfonic acids or sulfuric acid esters; Salts thereof derived from aliphatic hydrocarbons or mono-alcohols
- C11D1/146—Sulfuric acid esters
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/662—Carbohydrates or derivatives
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/72—Ethers of polyoxyalkylene glycols
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/92—Sulfobetaines ; Sulfitobetaines
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D2111/00—Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
- C11D2111/10—Objects to be cleaned
- C11D2111/14—Hard surfaces
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of oral care. The invention provides a tooth socket cleaning solution which comprises the following components in parts by mass: 1-5 parts of active oxygen substances; 6-40 parts of a surfactant; 1-8 parts of cocamidopropyl hydroxysultaine; 5-32 parts of a plant detergent; 1-5 parts of sodium lauroyl sarcosinate; 0.1-1 part of glycerol; 0.1-1 part of preservative; 0.1-1 part of mint essence; 7-85.7 parts of water. The invention also provides a preparation method of the tooth socket cleaning solution. The tooth socket cleaning solution can quickly remove more than 99.9 percent of bacteria in tooth sockets and other dental appliances in the process of using the tooth socket cleaning solution outside the oral cavity, can realize comprehensive cleaning, and has no damage to the tooth sockets and other dental appliances.
Description
Technical Field
The invention relates to the technical field of oral care, in particular to a tooth socket cleaning solution and a preparation method thereof.
Background
At present, the tidiness and the beauty of teeth are more and more concerned by people, and the tooth socket has a good tooth straightening effect as a tooth adjuster and a tooth fixer, and is one of important ways for ensuring the tidiness and the beauty of the teeth. The cleaning of the tooth socket is very critical to the health of teeth, and the tooth socket cleaning solution in the prior art has the defects of incomplete sterilization, long cleaning time, damage to the tooth socket and the like.
Therefore, the tooth socket cleaning solution which is efficient in sterilization, comprehensive in cleaning and environment-friendly and nondestructive to tooth sockets is developed and researched, and has very important economic and social values.
Disclosure of Invention
The invention aims to provide a tooth socket cleaning solution and a preparation method thereof aiming at the defects of the prior art. The tooth socket cleaning solution can quickly remove more than 99.9 percent of bacteria in tooth sockets and other dental appliances in the process of using the tooth socket cleaning solution outside the oral cavity, can realize comprehensive cleaning, and has no damage to the tooth sockets and other dental appliances.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides a tooth socket cleaning solution which comprises the following components in parts by mass:
preferably, the active oxygen species comprises hydrogen peroxide and/or peracetic acid.
Preferably, the surfactant comprises a foaming agent and a foam stabilizer, and the mass ratio of the foaming agent to the foam stabilizer is 3-8: 1.
Preferably, the foaming agent comprises two or three of sodium dodecyl sulfate, fatty alcohol-polyoxyethylene ether sulfate, alkyl glycoside surfactants, amino acid surfactants and alpha-olefin sulfonate.
Preferably, the foam stabiliser comprises two or three of lauryl dimethyl amine oxide, coco diacetyl amide ammonium oxide, coco amidopropyl ammonium oxide and an alkanolamide surfactant.
Preferably, the vegetable detergent comprises one or two of coconut oil ethyl oxide, palm oil ethyl oxide and olive oil ethyl oxide.
Preferably, the preservative comprises one or two of methylisothiazolinone, ethylparaben and propylparaben.
The invention also provides a preparation method of the tooth socket cleaning solution, which comprises the following steps:
1) mixing an active oxygen species, cocamidopropyl hydroxysultaine, sodium lauroyl sarcosinate, glycerol and water to obtain a mixture;
2) and mixing the mixture, a surfactant, a plant detergent, a preservative and mint essence to obtain the tooth socket cleaning solution.
Preferably, the mixing temperature in the step 1) is 50-70 ℃, and the time is 50-200 min; the mixing temperature in the step 2) is 30-50 ℃, and the mixing time is 50-200 min.
The invention has the beneficial effects that:
the tooth socket cleaning solution can quickly remove more than 99.9 percent of bacteria in tooth sockets and other dental appliances in the process of using the tooth socket cleaning solution outside the oral cavity, can realize comprehensive cleaning, and has no damage to the tooth sockets and other dental appliances.
Detailed Description
The invention provides a tooth socket cleaning solution which comprises the following components in parts by mass:
the tooth socket cleaning solution comprises 1-5 parts of active oxygen substances, preferably 2-4 parts, and more preferably 3 parts.
The active oxygen species of the present invention preferably comprise hydrogen peroxide and/or peracetic acid; when the active oxygen species comprises hydrogen peroxide and peracetic acid, the hydrogen peroxide and peracetic acid are preferably mixed in equal mass ratios.
The tooth socket cleaning solution comprises 6-40 parts of a surfactant, preferably 10-30 parts, more preferably 15-25 parts, and even more preferably 18-22 parts.
The surfactant preferably comprises a foaming agent and a foam stabilizer, and the mass ratio of the foaming agent to the foam stabilizer is preferably 3-8: 1, more preferably 4-6: 1, and even more preferably 5: 1.
The foaming agent preferably comprises two or three of sodium dodecyl sulfate, fatty alcohol-polyoxyethylene ether sulfate, alkyl glycoside surfactants, amino acid surfactants and alpha-alkenyl sulfonate; the components are preferably mixed in equal mass ratios; the amino acid surfactant is preferably sodium lauroyl sarcosinate; the foam stabilizer preferably comprises two or three of lauryl dimethyl amine oxide, coco diacetyl amide ammonium oxide, coco amidopropyl ammonium oxide and alkanolamide surfactants; the components are preferably mixed in equal mass ratios.
The tooth socket cleaning solution comprises 1-8 parts of cocamidopropyl hydroxysultaine, preferably 3-6 parts, and further preferably 4-5 parts; the cocamidopropyl hydroxysultaine is a botanical foaming agent.
The tooth socket cleaning solution comprises 5-32 parts of plant detergent, preferably 10-28 parts, more preferably 15-20 parts, and even more preferably 16-18 parts.
The vegetable detergent of the present invention preferably comprises one or two of coconut oil ethyl oxide, palm oil ethyl oxide and olive oil ethyl oxide; when the vegetable detergent contains both components, the two components are preferably mixed in an equal mass ratio.
The tooth socket cleaning solution comprises 1-5 parts of sodium lauroyl sarcosinate, preferably 2-4 parts, and further preferably 3 parts; the sodium lauroyl sarcosinate is a foam enhancer.
The tooth socket cleaning solution comprises 0.1-1 part of glycerol, preferably 0.3-0.8 part of glycerol, and further preferably 0.5-0.6 part of glycerol; the glycerin is a plant emollient and a foam stabilizer.
The tooth socket cleaning solution comprises 0.1-1 part of preservative, preferably 0.3-0.8 part, and more preferably 0.5-0.6 part.
The preservative of the present invention preferably comprises one or two of methylisothiazolinone, ethylparaben and propylparaben; when the preservative contains both components, the components are preferably mixed in an equal mass ratio.
The tooth socket cleaning solution comprises 0.1-1 part of mint essence, preferably 0.3-0.8 part, and further preferably 0.5-0.6 part.
The tooth socket cleaning solution comprises 7-85.7 parts of water, preferably 15-70 parts of water, more preferably 25-50 parts of water, and even more preferably 30-40 parts of water.
The invention also provides a preparation method of the tooth socket cleaning solution, which comprises the following steps:
1) mixing an active oxygen species, cocamidopropyl hydroxysultaine, sodium lauroyl sarcosinate, glycerol and water to obtain a mixture;
2) and mixing the mixture, a surfactant, a plant detergent, a preservative and mint essence to obtain the tooth socket cleaning solution.
The mixing temperature in the step 1) of the invention is preferably 50-70 ℃, more preferably 55-65 ℃, and more preferably 60 ℃; the mixing time is preferably 50 to 200min, more preferably 100 to 150min, and still more preferably 120 to 140 min.
Preferably, in step 1) of the present invention, the reactive oxygen species and water are mixed first, then with cocamidopropyl hydroxysultaine, sodium lauroyl sarcosinate, and finally with glycerin.
The mixing temperature in the step 2) of the invention is preferably 30-50 ℃, more preferably 35-45 ℃, and more preferably 40 ℃; the mixing time is preferably 50 to 200min, more preferably 100 to 150min, and still more preferably 120 to 140 min.
The technical solutions provided by the present invention are described in detail below with reference to examples, but they should not be construed as limiting the scope of the present invention.
Example 1
Mixing 0.1kg peroxyacetic acid with 1kg water, then adding 0.1kg cocamidopropyl hydroxysultaine and 0.1kg sodium lauroyl sarcosinate, and then adding 0.01kg glycerin, heating the obtained mixed solution to 52 ℃, and keeping for 70 min; then cooling the mixed solution to 32 ℃, adding 0.24kg of lauryl sodium sulfate, 0.24kg of sodium alcohol ether sulfate, 0.06kg of lauryl dimethyl amine oxide, 0.06kg of coconut oil diacetyl amide ammonium oxide, 0.25kg of palm oil ethyl oxide, 0.25kg of olive oil ethyl oxide, 0.01kg of methylisothiazolinone and 0.01kg of mint essence, and keeping the temperature at 32 ℃ for 60min to obtain the tooth socket cleaning solution.
The mouthpiece cleaning solution of example 1 was used outside the oral cavity, and the inhibition rate of staphylococcus aureus (ATCC6538 generation 6) was 99.9% and the inhibition rate of escherichia coli (escherichia coli 8099 generation 5) was 99.9% within 5 min.
Example 2
Mixing 0.3kg of peroxyacetic acid, 0.2kg of hydrogen peroxide and 8kg of water, then adding 0.8kg of cocamidopropyl hydroxysultaine and 0.5kg of sodium lauroyl sarcosinate, then adding 0.1kg of glycerol, heating the obtained mixed solution to 68 ℃, and keeping the temperature for 180 min; then the mixed solution is cooled to 48 ℃, 1.6kg of alkyl glycoside surfactant, 0.6kg of alpha-alkenyl sulfonic acid potassium, 1.1kg of sodium lauroyl sarcosine, 0.25kg of cocamidopropyl ammonium oxide, 0.25kg of alkanolamide surfactant, 2.2kg of coconut oil ethyl oxide, 0.05kg of ethylparaben, 0.05kg of propylparaben and 0.1kg of mint essence are added, and the mixture is kept at 48 ℃ for 170min to obtain the tooth socket cleaning solution.
The mouthpiece cleaning solution of example 2 was used outside the oral cavity, and the inhibition rate of staphylococcus aureus (ATCC6538 generation 6) was 99.92% and the inhibition rate of escherichia coli (escherichia coli 8099 generation 5) was 99.92% within 5 min.
Example 3
Mixing 0.3kg of hydrogen peroxide and 3kg of water, then adding 0.4kg of cocamidopropyl hydroxysultaine and 0.3kg of sodium lauroyl sarcosinate, and then adding 0.05kg of glycerin, heating the obtained mixed solution to 60 ℃, and keeping the temperature for 120 min; then cooling the mixed solution to 40 ℃, adding 1kg of sodium dodecyl sulfate, 0.6kg of sodium lauroyl sarcosinate, 0.2kg of dodecyl dimethyl amine oxide, 0.3kg of cocamidopropyl ammonium oxide, 1kg of coconut oil ethyl oxide, 1kg of olive oil ethyl oxide, 0.05kg of methylisothiazolinone and 0.05kg of mint essence, and keeping the temperature at 40 ℃ for 140min to obtain the tooth socket cleaning solution.
The mouthpiece cleaning solution of example 3 was used outside the oral cavity, and the inhibition rate of staphylococcus aureus (ATCC6538 generation 6) was 99.95% and the inhibition rate of escherichia coli (escherichia coli 8099 generation 5) was 99.95% within 5 min.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (9)
1. The tooth socket cleaning solution is characterized by comprising the following components in parts by mass:
2. the mouthpiece cleaning solution according to claim 1, wherein the active oxygen species comprises hydrogen peroxide and/or peracetic acid.
3. The mouthpiece cleaning solution according to claim 1 or 2, wherein the surfactant comprises a foaming agent and a foam stabilizer, and the mass ratio of the foaming agent to the foam stabilizer is 3-8: 1.
4. The mouthpiece cleaning solution according to claim 3, wherein the foaming agent comprises two or three of sodium lauryl sulfate, fatty alcohol polyoxyethylene ether sulfate, alkyl glycoside surfactant, amino acid surfactant, and alpha-olefin sulfonate.
5. The mouthpiece cleaning solution according to claim 4, wherein the foam stabilizer comprises two or three of dodecyl dimethyl amine oxide, coco diacetyl ammonium oxide, coco amidopropyl ammonium oxide, and alkanolamide surfactants.
6. The mouthpiece cleaning solution according to claim 4 or 5, wherein the vegetable detergent comprises one or two of coconut oil ethyl oxide, palm oil ethyl oxide and olive oil ethyl oxide.
7. The mouthpiece cleaning solution according to claim 6, wherein the preservative comprises one or two of methylisothiazolinone, ethylparaben and propylparaben.
8. The method for preparing a mouthpiece cleaning liquid according to any one of claims 1 to 7, comprising the steps of:
1) mixing an active oxygen species, cocamidopropyl hydroxysultaine, sodium lauroyl sarcosinate, glycerol and water to obtain a mixture;
2) and mixing the mixture, a surfactant, a plant detergent, a preservative and mint essence to obtain the tooth socket cleaning solution.
9. The preparation method according to claim 8, wherein the mixing in step 1) is carried out at 50-70 ℃ for 50-200 min; the mixing temperature in the step 2) is 30-50 ℃, and the mixing time is 50-200 min.
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