CN112915036A - Preparation method of antibacterial mouth wash - Google Patents

Preparation method of antibacterial mouth wash Download PDF

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Publication number
CN112915036A
CN112915036A CN201911231161.0A CN201911231161A CN112915036A CN 112915036 A CN112915036 A CN 112915036A CN 201911231161 A CN201911231161 A CN 201911231161A CN 112915036 A CN112915036 A CN 112915036A
Authority
CN
China
Prior art keywords
antibacterial
preparation
mouth wash
mouthwash
poloxamer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911231161.0A
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Chinese (zh)
Inventor
夏凡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing Polytechnic Institute
Original Assignee
Nanjing Polytechnic Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Polytechnic Institute filed Critical Nanjing Polytechnic Institute
Priority to CN201911231161.0A priority Critical patent/CN112915036A/en
Publication of CN112915036A publication Critical patent/CN112915036A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • A61K8/21Fluorides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a preparation method of antibacterial mouthwash. The method comprises the following specific steps: the following mixture is prepared by mixing water, glycerol, propylene glycol, sorbitol, poloxamer, sodium fluoride, menthol, tea extract, cetylpyridinium chloride, potassium sorbate and chitosan according to a certain weight ratio, stirring and mixing, and dissolving uniformly to obtain the product. The invention provides a preparation method of antibacterial mouthwash, which enables the mouthwash to be more continuously antibacterial.

Description

Preparation method of antibacterial mouth wash
Technical Field
The invention relates to a preparation method of antibacterial mouthwash.
Background
The mouth wash mainly comprises essence, surfactant, fluoride, strontium chloride, alcohol, water, etc., and can clean oral cavity and prevent dental caries and periodontitis. There are two kinds of concentrated and dilute, the concentrated one is diluted with water for use, and the dilute one can be used for direct gargling.
Gargling is the most common self-care method, and is generally gargled with clean water or brackish water. Some mouthwashes are combined with certain drugs to make mouth washes, which have the effect of assisting in preventing and controlling oral diseases. Rinsing the mouth can remove food residues in the oral cavity and keep the oral cavity clean.
Disclosure of Invention
The invention aims to provide a preparation method of antibacterial mouthwash.
The technical solution for realizing the purpose of the invention is as follows: preparation method of antibacterial mouthwash
Mass ratio of the components
Water 20
Glycerol 2
Propylene glycol 2
Sorbitol 2
Poloxamers 2
Sodium fluoride 2
Menthol 2
Tea leaf extract 2
Xipyrazamine 2
Potassium sorbate 1
Chitosan 1
The above proportions are based on the mass of water.
The invention provides a preparation method of antibacterial mouthwash, which comprises the following specific steps:
example 1:
(1) the mixture is prepared from 20 g of water, 2 g of glycerol, 2 g of propylene glycol, 2 g of sorbitol, 2 g of poloxamer, 2 g of sodium fluoride, 2 g of menthol, 2 g of tea extract, 2 g of cetylpyridinium chloride, 1 g of potassium sorbate and 1 g of chitosan according to the mixture ratio.
(2) The above mixture was stirred and mixed.
(3) The product is obtained after uniform dissolution.
Example 2:
(1) the mixture is prepared from 20 g of water, 2 g of glycerol, 2 g of propylene glycol, 2 g of sorbitol, 2.5 g of poloxamer, 2 g of sodium fluoride, 2 g of menthol, 2 g of tea extract, 2 g of cetylpyridinium chloride, 1 g of potassium sorbate and 1.5 g of chitosan according to the mixture ratio.
(2) The above mixture was stirred and mixed.
(3) The product is obtained after uniform dissolution.
Example 3:
(1) the mixture is prepared from 20 g of water, 2 g of glycerol, 2 g of propylene glycol, 2 g of sorbitol, 3 g of poloxamer, 2 g of sodium fluoride, 2 g of menthol, 2 g of tea extract, 2 g of cetylpyridinium chloride, 1 g of potassium sorbate and 2 g of chitosan according to the mixture ratio.
(2) The above mixture was stirred and mixed.
(3) The product is obtained after uniform dissolution.
Example 4:
(1) the mixture is prepared from 20 g of water, 2 g of glycerol, 2 g of propylene glycol, 2 g of sorbitol, 3 g of poloxamer, 2 g of sodium fluoride, 2 g of menthol, 2 g of tea extract, 2 g of cetylpyridinium chloride, 1 g of potassium sorbate and 2.5 g of chitosan according to the mixture ratio.
(2) The above mixture was stirred and mixed.
(3) The product is obtained after uniform dissolution.
Although the present invention has been described in detail with reference to the preferred embodiments, it is not to be construed as limiting the invention thereto. Various modifications and alterations may be made by those skilled in the art without departing from the spirit and scope of the invention. The scope of the invention should therefore be seen as that defined by the appended claims.

Claims (4)

1. A preparation method of antibacterial mouthwash is characterized by comprising the following steps:
(1) mixing the following mixture according to a certain weight ratio of water, glycerol, propylene glycol, sorbitol, poloxamer, sodium fluoride, menthol, tea extract, cetylpyridinium chloride, potassium sorbate and antibacterial agent
(2) Mixing the above mixture under stirring
(3) The product is obtained after uniform dissolution.
2. The method for preparing antibacterial mouth wash according to claim 1, wherein the poloxamer in step (1) is added in an amount of 2-3 g.
3. The method for preparing antibacterial mouth wash according to claim 1, wherein the antibacterial agent in step (1) is chitosan.
4. The method for preparing antibacterial mouth wash according to claim 1, wherein the antibacterial chitosan in step (1) is added in an amount of 1-2.5 g.
CN201911231161.0A 2019-12-05 2019-12-05 Preparation method of antibacterial mouth wash Pending CN112915036A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911231161.0A CN112915036A (en) 2019-12-05 2019-12-05 Preparation method of antibacterial mouth wash

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911231161.0A CN112915036A (en) 2019-12-05 2019-12-05 Preparation method of antibacterial mouth wash

Publications (1)

Publication Number Publication Date
CN112915036A true CN112915036A (en) 2021-06-08

Family

ID=76161254

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201911231161.0A Pending CN112915036A (en) 2019-12-05 2019-12-05 Preparation method of antibacterial mouth wash

Country Status (1)

Country Link
CN (1) CN112915036A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113559008A (en) * 2021-08-31 2021-10-29 吉林大学 Antibacterial mouth wash containing dihydroquercetin and preparation method thereof
CN114376956A (en) * 2022-02-24 2022-04-22 四川天福精细化工有限公司 Spray mouth wash and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113559008A (en) * 2021-08-31 2021-10-29 吉林大学 Antibacterial mouth wash containing dihydroquercetin and preparation method thereof
CN114376956A (en) * 2022-02-24 2022-04-22 四川天福精细化工有限公司 Spray mouth wash and preparation method thereof

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WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20210608