CN113209199A - Pure traditional Chinese medicine oil agent for promoting wound healing and application method thereof - Google Patents
Pure traditional Chinese medicine oil agent for promoting wound healing and application method thereof Download PDFInfo
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Abstract
The invention relates to the technical field of traditional Chinese medicine oil solutions, in particular to a pure traditional Chinese medicine oil solution for promoting wound healing and a using method thereof, wherein the pure traditional Chinese medicine oil solution comprises the following components in parts by weight: 10-15 parts of safflower, 2-5 parts of saffron, 20-30 parts of sesame oil, 10-20 parts of walnut oil, 5-10 parts of astragalus, 15-25 parts of cuttlebone, 2-5 parts of frankincense and 30-50 parts of rapeseed oil; cleaning wound, sterilizing, washing wound with normal saline, wiping, soaking medical gauze in the Chinese medicinal oil, and twisting to semi-dry state to completely wrap affected part; wrapping vaseline gauze outside the medical gauze; the invention can directly compensate and substitute the symptoms such as drug resistance, flora imbalance and the like generated by antibiotic treatment, can accelerate inflammatory exudation and excretion, improve metabolism, accelerate cell regeneration and repair skin tissue injury, and has good healing promoting effect on diabetic foot, pressure sore, burn and scald, skin ulceration, various acute wounds and the like.
Description
Technical Field
The invention relates to the technical field of medical dressings, in particular to a pure traditional Chinese medicine oil agent for promoting wound healing and a using method thereof.
Background
Chronic difficult-to-heal wound surface, called chronic wound for short, includes ulceration caused by diabetic foot, varicosity, angiitis and the like, bedsore, various wounds such as scald, burn, bone injury and the like and a series of clinical symptoms such as postoperative wound disunion and the like, and chronic wound is usually secondary to senile diseases, diabetes, radiotherapy and the like, including oppression, diabetes, radioactivity and the like.
With the increasing prevalence of various chronic diseases, the chronic wounds, such as pressure sores, diabetic feet, venous leg ulcers and the like, associated with the chronic diseases also show high morbidity. The clinical common wounds are mainly changed from acute wounds to chronic wounds, chronic wounds caused by various wounds, burns, scalds, non-healing wounds after operation, bedsores, diabetic feet and ecthyma (commonly called leg rotting) have jumped over the first morbidity, and the direct supplement of Fibronectin (FN) is the most direct and effective method for treating the chronic wounds.
Because a part of difficult-to-heal chronic injuries or ulcers are secondary to senile diseases, diabetes, radiotherapy and the like, the actual incidence rate of the diseases is higher when the diseases are mainly treated by internal medicine, radiotherapy, particularly surgical outpatient services and other related professional diagnosis and treatment, and the proportion of various ulcers such as pressure ulcers, diabetic ulcers, radioactive ulcers and the like is correspondingly increased; although the chronic ulcer which is difficult to cure does not immediately threaten life, the chronic ulcer which is difficult to cure is long for months, even years and decades, so that the primary disease recovery and the life quality of a patient are seriously influenced, heavy nursing and economic burden are brought to families, and the ulcer canceration can be generated in a small number. If infection spreads, complications such as sepsis can be caused, which not only aggravates the primary disease but also endangers the life of the patient.
Disclosure of Invention
The invention aims to provide a pure traditional Chinese medicine oil for promoting wound healing, inhibiting bacteria and resisting inflammation and promoting wound healing and a using method thereof.
In order to solve the technical problems, the invention adopts the technical scheme that the pure traditional Chinese medicine oil for promoting wound healing comprises the following components in parts by weight:
10-15 parts of safflower, 2-5 parts of saffron, 20-30 parts of sesame oil, 10-20 parts of walnut oil, 5-10 parts of astragalus, 15-25 parts of cuttlebone, 2-5 parts of frankincense and 30-50 parts of rapeseed oil.
Further, the composition comprises the following components in parts by weight:
12-13 parts of safflower, 3-4 parts of saffron, 23-27 parts of sesame oil, 13-17 parts of walnut oil, 6-8 parts of astragalus, 18-22 parts of cuttlebone, 3-4 parts of frankincense and 35-45 parts of rapeseed oil.
Further, 13 parts of safflower, 3 parts of saffron, 25 parts of sesame oil, 15 parts of walnut oil, 7 parts of astragalus, 20 parts of cuttlebone, 3 parts of frankincense and 40 parts of rapeseed oil.
Furthermore, the safflower has the functions of promoting blood circulation, dredging channels, eliminating swelling and relieving pain, and can be beneficial to pus discharge and toxin removal of sores, remove blood stasis and help muscles grow and grow flesh;
the saffron can improve peripheral microcirculation, prevent blood coagulation and reduce blood fat; the composite material has the advantages of improving the hypoxia tolerance of animals, enhancing the permeability of capillary vessels, improving blood supply, directly supplying oxygen to organism cells of wound surfaces and creating good conditions for wound surface healing;
sesame oil is sweet and cool in taste, has the effects of relaxing bowel, detoxifying and promoting granulation, and has the effects of moistening dryness, detoxifying, relieving pain and reducing swelling;
the walnut oil has the effects of resisting bacteria, diminishing inflammation, enhancing the vasodilating force, effectively activating cells, enhancing the immunity of a human body, resisting oxidation, delaying senescence and the like, can be quickly absorbed by the human body, promotes the blood circulation of the body, penetrates into adipose tissues, activates functional cells of the body, resists inflammation, sterilizes and repairs cells, has extremely strong biological permeability, and opens a channel for the absorption and administration of other traditional Chinese medicine components;
the cuttlebone is the inner shell of the cuttlefish, can astringe to stop bleeding, secure essence and stop leucorrhea, relieve soreness and pain, remove dampness and heal wound, and repair nerve cells, body cells and immunocytes, so that the cuttlebone can stop bleeding and relieve pain quickly;
ru Xiang has the action of promoting blood circulation to stop pain. Can be used for treating pain of heart and abdomen, spasm of tendons and vessels, traumatic injury, skin ulcer, carbuncle, and swelling and pain; swelling subsiding and tissue regeneration promoting are performed for external use;
rapeseed oil: promoting blood circulation to remove blood stasis; relieving swelling and dissipating stagnation; also has the effect of relieving body fluid toxin in vivo.
The pure traditional Chinese medicine oil agent for promoting wound healing provided by the application can directly make up and replace symptoms such as drug resistance and flora imbalance generated by antibiotic treatment, occupies living space of viruses and germs after repairing cells, is discharged outside the body, has the advantages of broad-spectrum antibiosis, less adverse reaction, difficulty in generating drug resistance and the like, can accelerate inflammatory exudation and excretion, improve metabolism and accelerate cell regeneration.
The method for using the pure traditional Chinese medicine oil comprises the following steps:
soaking medical gauze in pure Chinese medicinal oil, and twisting to half dry to completely wrap the affected part;
wrapping vaseline gauze outside the medical gauze;
bandaging and fixing;
the dressing change interval is 4h-1 d.
Further, after debridement and disinfection, the wound is washed by normal saline and wiped dry, and pure traditional Chinese medicine oil is soaked in medical gauze and is screwed to be half-dry, so that the medical gauze is completely wrapped on the affected part;
wrapping vaseline gauze outside the medical gauze;
and (5) bandaging and fixing.
Further, applying the pure Chinese medicinal oil to the affected part, and kneading and massaging.
The oily gauze is prepared from pure traditional Chinese medicine oil when in use, the oily gauze is filled into a wound or a sinus, the oily gauze is anti-inflammatory and antibacterial, and has good exudate drainage effect and air permeability due to non-closeness, and meanwhile, the oily gauze forms hydrogel after being contacted with wound exudate, so that a good moist healing environment is provided for the wound, the wound pain can be relieved, the effects of draining pus, drawing out poison, removing putrefaction, promoting granulation and healing sore can be achieved, and the wound healing is promoted.
Compared with the prior art, the invention has the advantages and positive effects that:
the saffron is used as a monarch drug, has sweet taste and mild property, has the effects of promoting blood circulation to remove blood stasis, dispersing stagnation and resolving masses, promoting granulation and relieving pain, and cooling blood and detoxifying, and the modern medical research also shows that the saffron can enhance the oxygen metabolism function in cells, enhance the cellular immunity and humoral immunity of organisms, improve the capillary circulation state and promote the repair of inflammatory injury under the condition of normal pressure and oxygen deficiency;
the cuttlebone is used as a ministerial drug and has the effects of stopping bleeding, astringing, relieving hyperacidity and healing ulcer;
the rapeseed oil is used as an adjuvant drug, assists the monarch and minister drugs to have the effects of developing the effects and enhancing the effects of clearing damp and reducing swelling, and promotes blood stagnation and qi breaking, can enter the blood system and has the effects of cooling blood and expelling toxin, can enter the lung channel and has the effect of promoting the growth of skin;
the walnut oil is a messenger drug, can promote various drugs to quickly reach focus, mainly contains phenolic acid and flavone components, and has the effects of oxidation resistance, inflammation resistance, virus resistance and immunoregulation.
The pure traditional Chinese medicine oil solution for promoting wound healing provided by the invention adopts pure traditional Chinese medicines, can directly compensate and replace symptoms such as drug resistance, flora imbalance and the like generated by antibiotic treatment through a physical compounding process, occupies living space of viruses and germs after repairing cells, is discharged out of a body, has the advantages of broad-spectrum antibiosis, less adverse reaction, difficult generation of drug resistance and the like, can accelerate inflammatory exudation and excretion, improve metabolism, accelerate cell regeneration and repair skin tissue injury, can relieve pain, relieve swelling and promote tissue regeneration, shorten repair time, efficiently promote wound healing, inhibit bacteria and resist inflammation, repair skin tissue injury, promote blood circulation and remove blood stasis, remove putrefaction, soften hardness and dissipate stagnation, improve microcirculation, repair nerve nets, repair blood vessels nets and promote recovery of various wounds, therefore, has the functions of anti-inflammation, anti-infection, rapid hemostasis and pain relief.
The wound healing process is a complex process which is controlled by a plurality of links, and mainly comprises reaction processes of synthesis and secretion of various growth factors, apoptosis, proliferation and control of cells, collagen metabolism and the like. The treatment of western medicines can only be intervened in a certain link simply, and can not achieve effective regulation of multiple links simultaneously. The components of the formula are used together, so that the effects of clearing heat and removing toxicity, relieving swelling and pain, expelling pus and removing putrefaction, promoting tissue regeneration and healing wound are achieved, the internal environment of wound surface tissue repair is improved, multiple links are repeated, and the rapid healing of the ulcer wound surface is promoted.
Detailed Description
Example 1:
10g of safflower, 2g of saffron, 20g of sesame oil, 10g of walnut oil, 5g of astragalus, 15g of cuttlebone and 2g of frankincense, and then adding 30g of rapeseed oil as a solvent.
Example 2:
11g of safflower, 3g of saffron, 22g of sesame oil, 12g of walnut oil, 6g of astragalus, 17g of cuttlebone and 3g of frankincense are extracted and blended, and 34g of rapeseed oil is added as a solvent.
Example 3:
12g of safflower, 4g of saffron, 24g of sesame oil, 14g of walnut oil, 7g of astragalus, 19g of cuttlebone and 4g of frankincense are extracted and blended, and 38g of rapeseed oil is added as a solvent.
Example 4:
13g of safflower, 5g of saffron, 26g of sesame oil, 16g of walnut oil, 8g of astragalus, 21g of cuttlebone and 5g of frankincense, and adding 42g of rapeseed oil as a solvent after extraction and blending.
Example 5:
14g of safflower, 5g of saffron, 28g of sesame oil, 18g of walnut oil, 9g of astragalus, 23g of cuttlebone and 5g of frankincense are extracted and blended, and 46g of rapeseed oil is added as a solvent.
Example 6:
15g of safflower, 5g of saffron, 30g of sesame oil, 20g of walnut oil, 10g of astragalus, 25g of cuttlebone and 5g of frankincense are extracted and blended, and 50g of rapeseed oil is added as a solvent.
The components in examples 1-6 are shown in Table 1:
TABLE 1 quality (g) of each component in examples 1-6
Experimental example 1:
the experimental example investigates the influence of the concentration of each component on the anti-inflammatory effect of the finished product.
Blank control group: pure rapeseed oil is adopted;
the formulations provided in examples 1 to 6 were used as experimental group a, experimental group B, experimental group C, experimental group D, experimental group E, and experimental group F, except that the concentrations of the active ingredients were different;
140 severe acne patients 18-25 years old are randomly combined and grouped, 20 persons in each group are washed, the faces of experimenters are washed, pure traditional Chinese medicine oil solutions provided in experimental groups A-F and a blank control group are soaked in medical gauze and are screwed to be semi-dry, the medical gauze completely wraps the right face of the patient for 30min, the medical gauze is removed and the faces are washed, the faces of the patients are detected by a VISIA skin detector, the improvement conditions of facial inflammation in the skin before and after acne treatment are detected by VISIA skin detection red zone index analysis, and the results are shown in Table 2.
TABLE 2 improvement of facial inflammation
| Group of | Experimental group A | Experimental group B | Experimental group C | Experimental group D |
| Amelioration of inflammation | 43.329±0.26 | 39.629±0.46 | 24.629±0.46 | 20.629±0.46 |
| Group of | Experimental group E | Experimental group F | Blank control group | |
| Amelioration of inflammation | 17.629±0.46 | 13.629±0.46 | 58.629±0.46 |
Through determination of inflammation improvement conditions, the effect that the concentration in the experimental groups A-F is higher is better, the effects can be achieved, the effects can be directly made up and replaced for symptoms such as drug resistance and flora imbalance generated by antibiotic treatment, after cells are repaired, living spaces of viruses and germs are squeezed out and discharged out of the body, the effects of broad-spectrum antibiosis, few adverse reactions, difficulty in generating drug resistance and the like are achieved, inflammatory exudation and excretion can be accelerated, metabolism is improved, cell regeneration is accelerated, skin tissue injury is repaired, and repair time can be shortened Softening hard mass and dissipating stagnation, improving microcirculation, repairing nerve network and blood vessel network, and promoting the recovery of various wound surfaces, so it has the functions of anti-inflammation, anti-infection, rapid hemostasis and relieving pain.
Experimental example 2:
the experimental examples examined the effect of the concentrations of the respective components on the biological activity.
Blank control group: pure rapeseed oil is adopted;
the formulations provided in examples 1 to 6 were used as experimental group a, experimental group B, experimental group C, experimental group D, experimental group E, and experimental group F, except that the concentrations of the active ingredients were different;
140 moderate diabetic patients were randomly grouped in groups of 20 patients each, the experimenters were debrided, the medicinal oil provided in the experimental groups a-F and the blank control group was fully soaked in sterile gauze for 24h to make oily gauze, oily gauze was filled into the wound or sinus, the dressing was changed every 12h for the first three days, the dressing was changed every 24h for the third-tenth days, and the curative effect was observed on 30 days, with the results shown in table 3.
TABLE 2 improvement of facial inflammation
| Group of | Experimental group A | Experimental group B | Experimental group C | Experimental group D |
| Recovery (%) | 60％ | 65％ | 70％ | 75％ |
| Significant effect (%) | 25％ | 25％ | 30％ | 25％ |
| Effective (%) | 15％ | 10％ | 0 | 0 |
| Null (%) | 0 | 0 | 0 | 0 |
| Group of | Experimental group E | Experimental group F | Blank control group | |
| Recovery (%) | 80％ | 80％ | 0 | |
| Significant effect (%) | 20％ | 20％ | 0 | |
| Effective (%) | 0 | 0 | 5％ | |
| Null (%) | 0 | 0 | 95％ |
Through the determination of inflammation improvement conditions, the formulas in the experimental groups A-F can play a good role in treating moderate diabetes foot, and the effect is better when the concentration is higher, so that the ulcer of the diabetic foot can be effectively inhibited, and the growth of new flesh can be stimulated.
The embodiments of the present invention have been described in detail, but the description is only for the preferred embodiments of the present invention and should not be construed as limiting the scope of the present invention. All equivalent changes and modifications made within the scope of the present invention should be covered by the present patent.
Claims (6)
1. A pure traditional Chinese medicine oil agent for promoting wound healing is characterized in that: the composition comprises the following components in parts by weight:
10-15 parts of safflower, 2-5 parts of saffron, 20-30 parts of sesame oil, 10-20 parts of walnut oil, 5-10 parts of astragalus, 15-25 parts of cuttlebone, 2-5 parts of frankincense and 30-50 parts of rapeseed oil.
2. The pure traditional Chinese medicine oil for promoting wound healing according to claim 1, is characterized in that: the composition comprises the following components in parts by weight:
12-13 parts of safflower, 3-4 parts of saffron, 23-27 parts of sesame oil, 13-17 parts of walnut oil, 6-8 parts of astragalus, 18-22 parts of cuttlebone, 3-4 parts of frankincense and 35-45 parts of rapeseed oil.
3. The pure traditional Chinese medicine oil for promoting wound healing according to claim 1, is characterized in that: the composition comprises the following components in parts by weight:
13 parts of safflower, 3 parts of saffron, 25 parts of sesame oil, 15 parts of walnut oil, 7 parts of astragalus, 20 parts of cuttlebone, 3 parts of frankincense and 40 parts of rapeseed oil.
4. A method of using the pure herbal oil of any of claims 1-3, wherein:
soaking medical gauze in pure Chinese medicinal oil, and twisting to half dry to completely wrap the affected part;
wrapping vaseline gauze outside the medical gauze;
bandaging and fixing;
the dressing change interval is 4h-1 d.
5. A method of using the pure herbal oil of any of claims 1-3, wherein:
cleaning wound, sterilizing, washing wound with normal saline, wiping, soaking medical gauze with pure Chinese medicinal oil, and twisting to semi-dry state to completely wrap affected part;
wrapping vaseline gauze outside the medical gauze;
and (5) bandaging and fixing.
6. A method of using the pure herbal oil of any of claims 1-3, wherein:
applying the Chinese medicinal oil to the affected part, and kneading and massaging.
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| CN115120656A (en) * | 2022-07-20 | 2022-09-30 | 河南济慈医药有限公司 | Medicine for wound repair and preparation method thereof |
| CN115120656B (en) * | 2022-07-20 | 2023-05-12 | 河南济慈医药有限公司 | A topical Chinese medicinal composition for wound repair, and its preparation method |
| CN115813973A (en) * | 2022-12-29 | 2023-03-21 | 中国人民解放军军事科学院军事医学研究院 | Application of Longyou in preparation of medicine for preventing and treating radiation enteritis |
| CN117618340A (en) * | 2023-10-20 | 2024-03-01 | 安徽龙纪元生物科技有限公司 | Dragon oil solution and method for debriding diabetic foot and chronic wound by using same |
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Application publication date: 20210806 |