CN113173984B - 一种新型光敏感通道蛋白vr1.0在制备视网膜感光细胞退行性疾病药物中的应用 - Google Patents
一种新型光敏感通道蛋白vr1.0在制备视网膜感光细胞退行性疾病药物中的应用 Download PDFInfo
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Abstract
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CN202110388643.8A CN113173984B (zh) | 2021-04-12 | 2021-04-12 | 一种新型光敏感通道蛋白vr1.0在制备视网膜感光细胞退行性疾病药物中的应用 |
PCT/CN2022/097893 WO2022218446A1 (zh) | 2021-04-12 | 2022-06-09 | 一种新型光敏感通道蛋白vr1.0在制备视网膜感光细胞退行性疾病药物中的应用 |
EP22787668.7A EP4324844A1 (en) | 2021-04-12 | 2022-06-09 | Use novel light sensitive channel protein vr 1.0 in preparation of retinal photoreceptor cell degenerative disease drug |
US18/120,007 US11981720B2 (en) | 2021-04-12 | 2023-03-10 | Use novel light sensitive channel protein VR 1.0 in preparation of retinal photoreceptor cell degenerative disease drug |
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US11981720B2 (en) | 2021-04-12 | 2024-05-14 | Zhongmou Therapeutics Co., Ltd. | Use novel light sensitive channel protein VR 1.0 in preparation of retinal photoreceptor cell degenerative disease drug |
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CN113173984B (zh) * | 2021-04-12 | 2022-08-30 | 中眸医疗科技(武汉)有限公司 | 一种新型光敏感通道蛋白vr1.0在制备视网膜感光细胞退行性疾病药物中的应用 |
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CN112010952A (zh) * | 2019-05-30 | 2020-12-01 | 上海视霁生物工程有限公司 | 光敏感通道ChR2蛋白的突变体及其应用 |
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US8580937B2 (en) * | 2011-03-14 | 2013-11-12 | Board Of Regents Of The University Of Texas System | cDNA-derived nucleic acids encoding red-shifted channelrhodopsins |
US8759492B2 (en) * | 2011-08-17 | 2014-06-24 | The Regents Of The University Of California | Engineered red-shifted channelrhodopsin variants |
US20150232528A1 (en) * | 2014-02-18 | 2015-08-20 | Board Of Regents Of The University Of Texas System | High-efficiency, sodium -specific, blue-shifted channelrhodopsins |
KR20170132427A (ko) * | 2016-05-24 | 2017-12-04 | 포항공과대학교 산학협력단 | 형질전환 예쁜꼬마선충을 이용한 수명 조절방법 |
MX2019002321A (es) * | 2016-08-29 | 2019-10-21 | Univ Wayne State | Identificación de mutaciones en variantes de opsina de canal con sensibilidad a la luz mejorada y métodos de uso de estas. |
CN112011554A (zh) * | 2019-05-30 | 2020-12-01 | 上海视霁生物工程有限公司 | 光敏感通道ChR2蛋白的优化表达及制备 |
CN113173984B (zh) * | 2021-04-12 | 2022-08-30 | 中眸医疗科技(武汉)有限公司 | 一种新型光敏感通道蛋白vr1.0在制备视网膜感光细胞退行性疾病药物中的应用 |
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US11981720B2 (en) | 2021-04-12 | 2024-05-14 | Zhongmou Therapeutics Co., Ltd. | Use novel light sensitive channel protein VR 1.0 in preparation of retinal photoreceptor cell degenerative disease drug |
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