CN113172011B - Circumferential step-by-step type reagent disk cleaning device for nucleic acid detection - Google Patents

Circumferential step-by-step type reagent disk cleaning device for nucleic acid detection Download PDF

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Publication number
CN113172011B
CN113172011B CN202110266945.8A CN202110266945A CN113172011B CN 113172011 B CN113172011 B CN 113172011B CN 202110266945 A CN202110266945 A CN 202110266945A CN 113172011 B CN113172011 B CN 113172011B
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fixedly connected
rod
steel pipe
block
transmission
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CN113172011A (en
Inventor
冯珍
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Guangzhou Ruineng Medical Technology Co ltd
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Guangzhou Ruineng Medical Technology Co ltd
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    • B08B1/143
    • B08B1/30
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B13/00Accessories or details of general applicability for machines or apparatus for cleaning
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/20Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/28Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by splash, spray, or jet application, with or without soaking
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/20Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/36Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by using brushes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention relates to the field of nucleic acid detection, in particular to a reagent disk cleaning device for circumferential step-by-step nucleic acid detection. The technical problem of the invention is as follows: provided is a circumferential stepwise cleaning device for a reagent disk for nucleic acid detection. The technical scheme is as follows: a circumference is step by step type nucleic acid detects and uses the cleaning device of the reagent disk, including chassis, drive assembly, sidewall wash assembly, tube wall wash assembly and control panel; the underframe is connected with the pipe wall cleaning assembly; the chassis is connected with the control screen; the transmission assembly is connected with the side wall cleaning assembly; the side wall cleaning component is connected with the pipe wall cleaning component. When the reagent tray is used, the outer side of the reagent tray is automatically cleaned, gaps among small containers on the outer ring of the reagent tray are cleaned, the small containers of the reagent tray are automatically cleaned and wiped one by one, and simultaneously, one large container is cleaned when every three small containers are cleaned, so that all containers on the reagent tray are cleaned, and the efficiency is greatly improved.

Description

Circumferential step-by-step type reagent disk cleaning device for nucleic acid detection
Technical Field
The invention relates to the field of nucleic acid detection, in particular to a reagent disk cleaning device for circumferential step-by-step nucleic acid detection.
Background
Nucleic acids are composed of nucleotides, whereas nucleotide monomers are composed of five-carbon sugars, phosphate groups and nitrogenous bases. If the five carbon sugar is ribose, the polymer formed is RNA; if the five carbon sugar is deoxyribose, the polymer formed is DNA.
In the prior art, one of the reagent discs for nucleic acid detection is provided with a plurality of groups of large containers and small containers, the large container is cylindrical, the small containers are in a test tube shape, the small containers are in a circular array and are arranged on an outer ring, the large containers are in a circular array and are arranged on an inner ring, the number of the small containers is three times that of the large containers, no device for cleaning the reagent discs is arranged at present, when the reagent discs are cleaned manually, the reagent discs are provided with the plurality of groups of large containers and the small containers, so that the manual cleaning efficiency is extremely low, meanwhile, the small containers are relatively thin and long, the inner walls of the small containers are difficult to clean manually, meanwhile, the bottoms of the small containers are round surfaces, the bottoms of the small containers cannot be cleaned completely manually, the small containers with the circular array on the outer ring of the reagent discs are relatively compact, small gaps are formed between the adjacent small containers, a solvent can drip into the gaps in the use process of the reagent discs, and impurities in the gaps are difficult to clean manually.
In summary, there is a need to develop a reagent disk cleaning device for circumferential stepwise nucleic acid detection to overcome the above problems.
Disclosure of Invention
In order to overcome the technical problems that in the prior art, a reagent disk for nucleic acid detection is provided with a plurality of groups of large containers and small containers, the large containers are cylindrical, the small containers are in a test tube shape, the small containers are in a circular array and are arranged on an outer ring, the large containers are in a circular array and are arranged on an inner ring, the number of the small containers is three times that of the large containers, no device for cleaning the reagent disk exists, when the reagent disk is manually cleaned, because the reagent disk is provided with the plurality of groups of large containers and small containers, the efficiency of manual cleaning is extremely low, meanwhile, the small containers are relatively slender, the inner walls of the small containers are difficult to clean manually, meanwhile, the bottoms of the small containers are circular surfaces, the bottoms of the small containers cannot be completely cleaned manually, meanwhile, the small containers with the circular array on the outer ring of the reagent disk are relatively compact, small gaps are formed between the adjacent small containers, a solvent can drip into the gaps in the use process of the reagent disk, and impurities in the gaps are difficult to clean manually, the invention has the technical problems that: provided is a circumferential stepwise nucleic acid detection reagent disk cleaning device.
The technical scheme is as follows: a circumference is step by step type nucleic acid detects and uses the cleaning device of the reagent disk, including chassis, drive assembly, sidewall wash assembly, tube wall wash assembly and control panel; the underframe is connected with the transmission assembly; the bottom frame is connected with the side wall cleaning assembly; the underframe is connected with the pipe wall cleaning assembly; the chassis is connected with the control screen; the transmission assembly is connected with the side wall cleaning assembly; the side wall cleaning component is connected with the pipe wall cleaning component.
In addition, it is particularly preferable that the transmission assembly comprises a first transmission rod, a first transmission wheel, a second transmission rod, a first bevel gear, a second bevel gear, a first electric push rod, a third bevel gear, a third transmission rod, a first single gear, a first rotating disc, a first limit ring, a first multi-stage electric telescopic rod and a first electric sucker; the outer surface of the first transmission rod is fixedly connected with the first transmission wheel; the outer surface of the first transmission rod is rotationally connected with the bottom frame; the outer surface of the first transmission rod is connected with the side wall cleaning component; the first driving wheel is in transmission connection with the second driving wheel through a belt; the inner part of the second driving wheel is fixedly connected with a second driving rod; the outer surface of the second transmission rod is fixedly connected with the first bevel gear; the outer surface of the second transmission rod is rotatably connected with the underframe; a second bevel gear is arranged on the side edge of the first bevel gear; the inner part of the second bevel gear is fixedly connected with the first electric push rod; a third bevel gear is arranged on the side edge of the second bevel gear; the first electric push rod is fixedly connected with the underframe; the inner part of the third bevel gear is fixedly connected with a third transmission rod; the lower part of the third transmission rod is fixedly connected with the first single gear; the outer surface of the third transmission rod is rotatably connected with the underframe; the first single gear is meshed with the first rotating disc; the first turntable is in rotating connection with the first limiting ring; the lower part of the first rotary disc is fixedly connected with a first multistage electric telescopic rod; the first limiting ring is fixedly connected with the underframe; the first multistage electric telescopic rod is fixedly connected with the first electric sucker.
In addition, it is particularly preferable that the side wall cleaning assembly includes a first motor, a first loop bar, a first prism bar, a first slider, a first electric slide rail, a fourth bevel gear, a fifth bevel gear, a first bidirectional screw rod, a second slider, a third slider, a first guide rail block, a second electric push rod, a first linkage block, a first sponge block, a third electric push rod, a second linkage block, and a second sponge block; the upper part of the first motor is fixedly connected with the first sleeve rod; the first motor is fixedly connected with the underframe; the inner part of the first sleeve rod is connected with the first prismatic rod; the outer surface of the first sleeve rod is rotatably connected with the bottom frame; the outer surface of the first sleeve rod is connected with the pipe wall cleaning assembly; the outer surface of the first prismatic rod is rotationally connected with the first sliding block; the outer surface of the first prismatic rod is fixedly connected with a fourth bevel gear; the first sliding block is in sliding connection with the first electric sliding rail; the first electric slide rail is fixedly connected with the underframe; a fifth bevel gear is arranged above the fourth bevel gear; the inner part of the fourth bevel gear is fixedly connected with the first transmission rod; the interior of the fifth bevel gear is fixedly connected with the first bidirectional screw rod; the outer surface of the first bidirectional screw rod is sequentially connected with the second sliding block and the third sliding block in a screwing manner; the outer surface of the first bidirectional screw rod is rotationally connected with the first guide rail block; the inside of the second sliding block is connected with the first guide rail block in a sliding way; the second sliding block is fixedly connected with a second electric push rod; the third slide block is connected with the first guide rail block in a sliding manner; the third sliding block is fixedly connected with a third electric push rod; the first guide rail block is fixedly connected with the bottom frame; the second electric push rod is fixedly connected with the first linkage block; the first linkage block is fixedly connected with the first sponge block; the third electric push rod is fixedly connected with the second linkage block; the second linkage block is fixedly connected with the second sponge block.
In addition, it is particularly preferable that the pipe wall cleaning assembly includes a third transmission wheel, a fourth transmission wheel, a first steel pipe, a first spur gear, a first brush, a first sprinkler head group, a first semicircular cover, a first rubber frame, a first limit cylinder, a fourth electric push rod, a first support frame, a first limit box, a second steel pipe, a first sponge rod, a third steel pipe, a first water pump, a first storage box, a first connection block, a first flexible hose, a fourth steel pipe, a second sprinkler head group, a third sprinkler head group, a second rubber frame, a second limit cylinder, a fifth electric push rod, a second support frame, a second sponge rod, a sixth electric push rod, a fourth transmission rod, a second spur gear and a third spur gear; the third driving wheel is in transmission connection with the fourth driving wheel through a belt; the inner part of the third driving wheel is fixedly connected with the first sleeve rod; the inner part of the fourth driving wheel is fixedly connected with the first steel pipe; the outer surface of the first steel pipe is fixedly connected with the first straight gear; the outer surface of the first steel pipe is fixedly connected with the first brush; the outer surface of the first steel pipe is fixedly connected with the first water spraying head group; the upper part of the first steel pipe is fixedly connected with the first semicircular cover; the first steel pipe is fixedly connected with the first rubber frame; the outer surface of the first steel pipe is rotationally connected with the first support frame; the outer surface of the first steel pipe is rotatably connected with the first limiting box; the lower part of the first steel pipe is rotationally connected with the third steel pipe; a first limiting cylinder is arranged on the outer side of the first steel pipe; the first steel pipe is fixedly connected with the underframe; the first limiting cylinder is fixedly connected with the fourth electric push rod; the first limiting cylinder is connected with the first support frame in a sliding manner; the fourth electric push rod is fixedly connected with the first support frame; the first support frame is fixedly connected with the first limiting box; the first support frame is fixedly connected with the first sponge rod; the first support frame is fixedly connected with the underframe; the first limiting box is fixedly connected with the second steel pipe; the third steel pipe is fixedly connected with the first water pump; the outer surface of the third steel pipe is fixedly connected with the first connecting block; the third steel pipe is fixedly connected with the first flexible hose; the first water pump is fixedly connected with the first storage box; the first storage box is fixedly connected with the first connecting block; the lower part of the first storage box is fixedly connected with the underframe; the first flexible hose is rotatably connected with the fourth steel pipe; the outer surface of the upper part of the first telescopic hose is fixedly connected with the second support frame; the outer surface of the lower part of the fourth steel pipe is rotatably connected with the second support frame; the fourth steel pipe is fixedly connected with the second water spray head group; the fourth steel pipe is fixedly connected with the third water spray head group; the fourth steel pipe is fixedly connected with the second rubber frame; a second limiting cylinder is arranged on the outer side of the fourth steel pipe; the second limiting cylinder is fixedly connected with the fifth electric push rod; the second limiting cylinder is in sliding connection with the second support frame; the fifth electric push rod is fixedly connected with the second support frame; the second supporting frame is fixedly connected with the second sponge rod; the second support frame is fixedly connected with the sixth electric push rod; the second support frame is rotatably connected with the fourth transmission rod; the outer surface of the fourth transmission rod is fixedly connected with the second straight gear; the second spur gear is meshed with the third spur gear.
In addition, it is particularly preferred that the outer annular surface of the first single gear is provided with a projection, and the inner annular surface of the first rotary disk is provided with a plurality of groups of grooves at equal intervals.
In addition, it is particularly preferable that the first sponge block and the second sponge block are provided with high-density sponges on opposite sides, and the two sponge blocks are provided with projections on opposite sides at equal intervals.
Furthermore, it is particularly preferred that the first rubber mount consists of a quarter-circle ring and an elongated circle ring.
Further, it is particularly preferable that the two vertically elongated blocks of the second rubber mount are circular arc blocks, and the lower portions of the two vertical blocks are each provided with one projection.
Compared with the prior art, the invention has the following advantages: the reagent disc comprises a reagent disc body, a plurality of groups of large containers and small containers, wherein the large containers are cylindrical, the small containers are in a test tube shape, the small containers are in a circular array and are arranged on an outer ring, the large containers are in a circular array and are arranged on an inner ring, the number of the small containers is three times that of the large containers, and no device for cleaning the reagent disc body exists at present;
designing a transmission assembly, a side wall cleaning assembly and a pipe wall cleaning assembly; when in preparation, the device is fixed on a horizontal plane, the power supply is switched on, the reagent disk to be cleaned is placed in the transmission component upside down, the control screen control device on the control bottom frame starts to operate, the transmission assembly fixes the reagent tray, the opening of the reagent tray faces downwards, the transmission assembly drives the reagent tray to move downwards to the inner part of the side wall cleaning assembly, then the side wall cleaning component is used for rubbing and cleaning the side wall of the reagent tray, and simultaneously the side wall cleaning component is used for cleaning the gap of the reagent tray container, then the transmission component drives the reagent tray to move downwards to the tube wall cleaning component, so that part of the tube wall cleaning component is positioned in one small container on the outer ring of the reagent tray, then the pipe wall cleaning component is opened to uniformly wet the small container from the inside, the pipe wall cleaning component cleans the round surface at the top of the small container, then the transmission component drives the reagent tray to do small-amplitude up-and-down reciprocating motion, the inner wall of the small container is cleaned by matching with the pipe wall cleaning component, meanwhile, the pipe wall cleaning component guides water for cleaning the small container to prevent water from splashing, wets and cleans a large container of the reagent tray, cleans a chamfer at the opening of the large container at the same time, then the transmission component drives the reagent tray to move upwards to separate from the pipe wall cleaning component, then the transmission component drives the reagent tray to rotate, so that the second small container is positioned at the initial position of the first small container, then the operation is repeated to clean the second small container, and simultaneously the pipe wall cleaning component removes the water of the first small container, cleaning the small containers of the reagent tray in a reciprocating manner, and cleaning the large container once by cleaning three small container pipe wall cleaning assemblies in the process, so that the containers on the reagent tray are cleaned;
when the reagent tray is used, the outer side of the reagent tray is automatically cleaned, gaps among the small containers on the outer ring of the reagent tray are cleaned, the small containers of the reagent tray are automatically cleaned and wiped one by one, and simultaneously, one large container is cleaned when every three small containers are cleaned, so that all containers on the reagent tray are cleaned, and the efficiency is greatly improved.
Drawings
FIG. 1 is a schematic perspective view of a first embodiment of the present invention;
FIG. 2 is a schematic perspective view of a second embodiment of the present invention;
FIG. 3 is a perspective view of the transmission assembly of the present invention;
FIG. 4 is a schematic perspective view of a sidewall cleaning assembly according to the present invention;
FIG. 5 is a schematic perspective view of a tube wall cleaning assembly according to the present invention;
FIG. 6 is a perspective view of a first portion of the tube wall cleaning assembly of the present invention;
FIG. 7 is a perspective view of a second portion of the tube wall cleaning assembly of the present invention;
FIG. 8 is a schematic perspective view of a second rubber frame according to the present invention.
In the figure: 1. a chassis, 2, a transmission assembly, 3, a side wall cleaning assembly, 4, a pipe wall cleaning assembly, 5, a control screen, 201, a first transmission rod, 202, a first transmission wheel, 203, a second transmission wheel, 204, a second transmission rod, 205, a first bevel gear, 206, a second bevel gear, 207, a first electric push rod, 208, a third bevel gear, 209, a third transmission rod, 2010, a first single gear, 2011, a first turntable, 2012, a first limit ring, 2013, a first multi-stage electric telescopic rod, 2014, a first electric suction cup, 301, a first motor, 302, a first sleeve rod, 303, a first prism rod, 304, a first slide block, 305, a first electric slide rail, 306, a fourth bevel gear, 307, a fifth bevel gear, 308, a first bidirectional guide rail, 309, a second slide block, 3010, a third slide block, 3011, a first guide rail block, 3012, a second electric push rod, 3013, a first linkage block, 3014, a first sponge block, 3015, a third electric push rod, 3016, a second linkage block, 3017, a second sponge block, 401, a third transmission wheel, 402, a fourth transmission wheel, 403, a first steel pipe, 404, a first straight gear, 405, a first brush, 406, a first water spray head group, 407, a first semicircular cover, 408, a first rubber frame, 409, a first limiting cylinder, 4010, a fourth electric push rod, 4011, a first support frame, 4012, a first limiting box, 4013, a second steel pipe, 4014, a first sponge rod, 4015, a third steel pipe, 4016, a first water pump, 4017, a first storage box, 4018, a first connecting block, 4019, a first telescopic hose, 4020, a fourth steel pipe, 4021, a second water spray head group, 4022, a third head group, 4023, a second rubber frame, 4024, a second limiting cylinder, 4025, a fifth electric push rod, 4026, a second support frame, 4027, a second sponge rod, 4028, 4029, a third sponge head group, 4023, a second sponge rod, 4024, 4026, a third electric push rod, 4026, a fourth electric push rod, a fourth support frame, A fourth transmission rod 4030, a second spur gear 4031 and a third spur gear.
Detailed Description
Although the present invention may be described with respect to particular applications or industries, those skilled in the art will recognize the broader applicability of the invention. Those of ordinary skill in the art will recognize techniques such as: terms such as above, below, upward, downward, and the like are used to describe the accompanying drawings and are not meant to limit the scope of the invention, which is defined by the appended claims. Such as: any numerical designation of first or second, and the like, is merely exemplary and is not intended to limit the scope of the invention in any way.
Example 1
A circumference is step by step type nucleic acid detection and uses the cleaning device of the reagent disk, as shown in fig. 1-8, including chassis 1, drive assembly 2, sidewall wash assembly 3, tube wall wash assembly 4 and control screen 5; the underframe 1 is connected with the transmission component 2; the underframe 1 is connected with the side wall cleaning component 3; the underframe 1 is connected with the pipe wall cleaning component 4; the underframe 1 is connected with a control screen 5; the transmission component 2 is connected with the side wall cleaning component 3; the side wall cleaning component 3 is connected with the pipe wall cleaning component 4.
The working steps are as follows: when the device is prepared for work, the device is fixed on a horizontal plane, a power supply is switched on, a reagent tray to be cleaned is placed in a transmission assembly 2 upside down, a control screen 5 on a control chassis 1 controls a control device to start to operate, the transmission assembly 2 fixes the reagent tray, the opening of the reagent tray faces downwards at the moment, the transmission assembly 2 drives the reagent tray to move downwards to the inside of a side wall cleaning assembly 3, then the side wall cleaning assembly 3 performs friction cleaning on the side wall of the reagent tray, meanwhile, the side wall cleaning assembly 3 cleans gaps of containers of the reagent tray, then the transmission assembly 2 drives the reagent tray to move downwards to a tube wall cleaning assembly 4, so that part of assemblies of the tube wall cleaning assembly 4 are positioned in one small container on the outer ring of the reagent tray, then the tube wall cleaning assembly 4 uniformly wets the small container from the inside, and the tube wall cleaning assembly 4 cleans the circular surface of the top of the small container, then the transmission component 2 drives the reagent tray to do reciprocating motion up and down with small amplitude, the inner wall of the small container is cleaned by matching with the pipe wall cleaning component 4, meanwhile, the pipe wall cleaning component 4 guides water for cleaning the small container to prevent water from splashing, meanwhile, the pipe wall cleaning component 4 wets and cleans the large container of the reagent tray, the chamfer at the opening of the large container is cleaned, then the transmission component 2 drives the reagent tray to move upwards to separate from the pipe wall cleaning component 4, then the transmission component 2 drives the reagent tray to rotate, so that the second small container is positioned at the initial position of the first small container, then the operations are repeated to clean the second small container, meanwhile, the pipe wall cleaning component 4 removes water of the first small container completely, the small containers of the reagent tray are cleaned in such a reciprocating way, and in the process, the large container is cleaned by cleaning component 4 for the pipe wall of each three small containers, when the automatic cleaning device is used, the outer side of the reagent disc is automatically cleaned, gaps among the small containers on the outer ring of the reagent disc are simultaneously cleaned, the small containers of the reagent disc are automatically cleaned and wiped one by one, and simultaneously, one large container is cleaned when every three small containers are cleaned, so that all containers on the reagent disc are cleaned, and the efficiency is greatly improved.
According to the invention, the transmission assembly 2 comprises a first transmission rod 201, a first transmission wheel 202, a second transmission wheel 203, a second transmission rod 204, a first bevel gear 205, a second bevel gear 206, a first electric push rod 207, a third bevel gear 208, a third transmission rod 209, a first single gear 2010, a first rotating disc 2011, a first limit ring 2012, a first multi-stage electric telescopic rod 2013 and a first electric sucking disc 2014; the outer surface of the first transmission rod 201 is fixedly connected with the first transmission wheel 202; the outer surface of the first transmission rod 201 is rotationally connected with the underframe 1; the outer surface of the first transmission rod 201 is connected with the side wall cleaning component 3; the first driving wheel 202 is in driving connection with a second driving wheel 203 through a belt; the inside of the second driving wheel 203 is fixedly connected with a second transmission rod 204; the outer surface of the second transmission rod 204 is fixedly connected with a first bevel gear 205; the outer surface of the second transmission rod 204 is rotatably connected with the underframe 1; a second bevel gear 206 is arranged on the side of the first bevel gear 205; the inner part of the second bevel gear 206 is fixedly connected with a first electric push rod 207; a third bevel gear 208 is arranged on the side of the second bevel gear 206; the first electric push rod 207 is fixedly connected with the underframe 1; the inside of the third bevel gear 208 is fixedly connected with a third transmission rod 209; the lower part of the third transmission rod 209 is fixedly connected with the first single gear 2010; the outer surface of the third transmission rod 209 is rotationally connected with the underframe 1; the first single gear 2010 is meshed with the first rotating disc 2011; the first rotating disc 2011 is rotatably connected with the first limit ring 2012; the lower part of the first rotating disc 2011 is fixedly connected with a first multistage electric telescopic rod 2013; the first limit ring 2012 is fixedly connected with the chassis 1; the first multi-stage electric telescopic rod 2013 is fixedly connected with the first electric sucking disc 2014.
Firstly, a reagent tray is placed upside down under a first limiting ring 2012 and is in contact with a first electric sucking disc 2014, then a control device of a control panel 5 is controlled to start to operate, three groups of first electric sucking discs 2014 simultaneously fix the reagent tray, the opening of the reagent tray faces downwards, then three groups of first multistage electric telescopic rods 2013 respectively drive three groups of first electric sucking discs 2014 to move downwards, so that three groups of first electric sucking discs 2014 simultaneously drive the reagent tray to move into a side wall cleaning component 3, the side wall cleaning component 3 cleans the side wall of the reagent tray, then the first multistage electric telescopic rods 2013 drive the first electric sucking discs 2014 to move downwards, the first electric sucking discs 2014 drive the reagent tray to move into a pipe wall cleaning component 4, the pipe wall cleaning component 4 cleans the round surface part of one small container in the outer ring of the reagent tray, and then the first multistage electric telescopic rods 2013 drive the first electric sucking discs 2014 to drive the reagent tray to move upwards and downwards in a reciprocating manner with small amplitude, so that the inner wall of the small container is cleaned by the tube wall cleaning assembly 4, then the first electric sucker 2014 stops driving the reagent tray to move, the large container in the reagent tray is cleaned by the tube wall cleaning assembly 4, then the first multi-stage electric telescopic rod 2013 drives the first electric sucker 2014 to drive the reagent tray to move upwards to separate from the tube wall cleaning assembly 4, then the first transmission rod 201 is driven by the side wall cleaning assembly 3 to drive the first transmission wheel 202 to rotate, the second transmission wheel 203 is driven by the first transmission wheel 202 to drive the second transmission rod 204 to rotate, the first bevel gear 205 is driven by the second transmission rod 204 to rotate, then the second bevel gear 206 is driven by the first electric push rod 207 to move towards the first bevel gear 205, so that the second bevel gear 206 is simultaneously meshed with the first bevel gear 205 and the third bevel gear 208, and the first bevel gear 205 drives the second bevel gear 206 to drive the third bevel gear 208 to rotate, third bevel gear 208 drives third transfer line 209 transmission first single gear 2010 to rotate, first single gear 2010 drives first carousel 2011 and carries out the pause-type and rotates, first carousel 2011 rotates certain angle this moment, first carousel 2011 drives first multistage electric telescopic handle 2013 transmission first electric sucking disc 2014 and rotates, first electric sucking disc 2014 drives the reagent dish and rotates, make the second cuvette be located the initial position of first cuvette, then repeat above-mentioned operation and wash the second cuvette, realized during the use that the automatic reagent dish that drives moves among lateral wall cleaning assembly 3 and pipe wall cleaning assembly 4, realized simultaneously that the automatic reagent dish that drives carries out the pause-type rotation, cooperation pipe wall cleaning assembly 4 washs the container on the reagent dish one by one.
In the invention, the side wall cleaning assembly 3 comprises a first motor 301, a first sleeve rod 302, a first prismatic rod 303, a first sliding block 304, a first electric sliding rail 305, a fourth bevel gear 306, a fifth bevel gear 307, a first bidirectional screw rod 308, a second sliding block 309, a third sliding block 3010, a first guide rail block 3011, a second electric push rod 3012, a first linkage block 3013, a first sponge block 3014, a third electric push rod 3015, a second linkage block 3016 and a second sponge block 3017; the upper part of the first motor 301 is fixedly connected with the first sleeve rod 302; the first motor 301 is fixedly connected with the underframe 1; the first sleeve 302 is internally connected with a first prismatic rod 303; the outer surface of the first loop bar 302 is rotatably connected with the underframe 1; the outer surface of the first loop bar 302 is connected with the pipe wall cleaning component 4; the outer surface of the first prismatic rod 303 is rotatably connected with a first sliding block 304; the outer surface of the first prismatic rod 303 is fixedly connected with a fourth bevel gear 306; the first sliding block 304 is connected with the first electric sliding rail 305 in a sliding manner; the first electric slide rail 305 is fixedly connected with the chassis 1; a fifth bevel gear 307 is arranged above the fourth bevel gear 306; the inside of the fourth bevel gear 306 is fixedly connected with the first transmission rod 201; the interior of the fifth bevel gear 307 is fixedly connected with a first bidirectional screw 308; the outer surface of the first bidirectional screw rod 308 is sequentially connected with the second sliding block 309 and the third sliding block 3010 in a screwing manner; the outer surface of the first bidirectional screw rod 308 is rotatably connected with the first guide rail block 3011; the inside of the second slide block 309 is connected with the first guide rail block 3011 in a sliding manner; the second sliding block 309 is fixedly connected with a second electric push rod 3012; the third slider 3010 is connected to the first rail block 3011 in a sliding manner; the third slider 3010 is fixedly connected to the third electric push rod 3015; the first guide rail block 3011 is fixedly connected with the underframe 1; the second electric push rod 3012 is fixedly connected with the first linkage block 3013; the first linkage block 3013 is fixedly connected with the first sponge block 3014; the third electric push rod 3015 is fixedly connected with the second linkage block 3016; the second linkage block 3016 is fixedly connected to the second sponge block 3017.
When the reagent disk is transported to the middle of the first sponge block 3014 and the second sponge block 3017 by the transmission assembly 2, the first motor 301 drives the first sleeve rod 302 to drive the first prism rod 303 to rotate, the first sleeve rod 302 drives the transmission assembly 2 and the tube wall cleaning assembly 4 to operate, the first prism rod 303 drives the fourth bevel gear 306 to rotate, then the first electric slide rail 305 drives the first slide block 304 to move upwards, the first slide block 304 drives the first prism rod 303 to drive the fourth bevel gear 306 to move upwards, so that the fourth bevel gear 306 is engaged with the fifth bevel gear 307, then the fourth bevel gear 306 drives the fifth bevel gear 307 to drive the first bidirectional screw rod 308 to rotate, the first bidirectional screw rod 308 drives the second slide block 309 and the third slide block 3010 to slide upwards on the first guide block 3011, the second slide block 309 drives the second electric push rod 3012 to drive the first linkage block 3013 to move, the first push rod 3013 drives the first sponge block 3014 to move, the third slide block 3015 to drive the second linkage block 3016 to move, the second sponge block 3016 and the second sponge block 3017 to drive the second sponge block 3014 to move in a reciprocating manner, so that the second sponge block 3014 and the second sponge block 3017 to move in a reciprocating motion, so that the second sponge block 3014 and a small sponge block 3017 to hold a reagent disk in a reciprocating motion, so that the second sponge block and a small sponge block 3017 to hold a reagent disk in a reciprocating motion, and a reciprocating motion, so that the second sponge block 304 in a reciprocating motion, and a small sponge block 3014, and a small sponge block 3017 to hold a small sponge block in a reciprocating motion, so that the reciprocating motion, meanwhile, gaps among the small containers on the outer ring of the reagent tray are cleaned, then the fourth bevel gear 306 is meshed with the fifth bevel gear 307, the first motor 301 rotates reversely to enable the first sponge block 3014 and the second sponge block 3017 to move back to the original position, then the fourth bevel gear 306 is stopped meshed with the fifth bevel gear 307, the reagent tray is used for automatically cleaning the outer side of the reagent tray, and meanwhile gaps among the small containers on the outer ring of the reagent tray are cleaned.
In the invention, the pipe wall cleaning assembly 4 comprises a third transmission wheel 401, a fourth transmission wheel 402, a first steel pipe 403, a first straight gear 404, a first brush 405, a first water spray head group 406, a first semicircular cover 407, a first rubber frame 408, a first limit cylinder 409, a fourth electric push rod 4010, a first support frame 4011, a first limit box 4012, a second steel pipe 4013, a first sponge rod 4014, a third steel pipe 4015, a first water pump 4016, a first storage box 4017, a first connecting block 4018, a first telescopic hose 4019, a fourth steel pipe 4020, a second water spray head group 4021, a third water spray head group 4022, a second rubber frame 4023, a second limit cylinder 4024, a fifth electric push rod 4025, a second support frame 4026, a second sponge rod 4027, a sixth electric push rod 4028, a fourth transmission rod 4029, a second straight gear 4030 and a third straight gear 4031; the third transmission wheel 401 is in transmission connection with a fourth transmission wheel 402 through a belt; the interior of the third transmission wheel 401 is fixedly connected with the first sleeve 302; the inside of the fourth driving wheel 402 is fixedly connected with the first steel pipe 403; the outer surface of the first steel pipe 403 is fixedly connected with a first straight gear 404; the outer surface of the first steel pipe 403 is fixedly connected with a first brush 405; the outer surface of the first steel pipe 403 is fixedly connected with the first water spray head group 406; the upper part of the first steel pipe 403 is fixedly connected with a first semicircular cover 407; the first steel pipe 403 is fixedly connected with the first rubber frame 408; the outer surface of the first steel pipe 403 is rotatably connected with the first support frame 4011; the outer surface of the first steel pipe 403 is rotatably connected with a first limit box 4012; the lower part of the first steel pipe 403 is rotatably connected with a third steel pipe 4015; a first limiting cylinder 409 is arranged on the outer side of the first steel pipe 403; the first steel pipe 403 is fixedly connected with the underframe 1; the first limiting cylinder 409 is fixedly connected with a fourth electric push rod 4010; the first limiting cylinder 409 is in sliding connection with the first supporting frame 4011; the fourth electric push rod 4010 is fixedly connected with the first support frame 4011; the first supporting frame 4011 is fixedly connected with a first limit box 4012; the first support frame 4011 is fixedly connected with a first sponge rod 4014; the first support frame 4011 is fixedly connected with the underframe 1; the first limit box 4012 is fixedly connected with a second steel pipe 4013; the third steel pipe 4015 is fixedly connected with a first water pump 4016; the outer surface of the third steel pipe 4015 is fixedly connected with a first connecting block 4018; the third steel pipe 4015 is fixedly connected with a first telescopic hose 4019; the first water pump 4016 is fixedly connected with the first storage box 4017; the first storage box 4017 is fixedly connected with the first connecting block 4018; the lower part of the first storage box 4017 is fixedly connected with the underframe 1; the first telescopic hose 4019 is rotatably connected with the fourth steel pipe 4020; the outer surface of the upper part of the first telescopic hose 4019 is fixedly connected with the second support frame 4026; the outer surface of the lower part of the fourth steel pipe 4020 is rotatably connected with a second support frame 4026; the fourth steel pipe 4020 is fixedly connected with the second water spray head group 4021; the fourth steel pipe 4020 is fixedly connected with the third water spray head group 4022; the fourth steel pipe 4020 is fixedly connected with the second rubber frame 4023; a second limiting cylinder 4024 is arranged on the outer side of the fourth steel pipe 4020; the second limiting cylinder 4024 is fixedly connected with the fifth electric push rod 4025; the second limiting cylinder 4024 is in sliding connection with the second supporting frame 4026; the fifth electric push rod 4025 is fixedly connected with the second support 4026; the second support 4026 is fixedly connected with a second sponge bar 4027; the second support 4026 is fixedly connected with a sixth electric push rod 4028; the second support 4026 is rotatably connected with the fourth transmission rod 4029; the outer surface of the fourth transmission rod 4029 is fixedly connected with a second straight gear 4030; the second spur gear 4030 meshes with the third spur gear 4031.
When the side wall cleaning component 3 cleans the side wall of the reagent tray, the transmission component 2 drives the reagent tray to move downwards, so that one small container in the outer ring of the reagent tray is inserted into the outer side of the first steel pipe 403, the first rubber frame 408 is tightly attached to the round surface of the small container, the lower part of the reagent tray is contacted with the first limiting cylinder 409, the first storage box 4017 is provided with a proper amount of clean water in advance, then the first water pump 4016 starts to work, so that the clean water flows to the first steel pipe 403 through the third steel pipe 4015 on the first connecting block 4018, the clean water is ejected upwards in a fan shape from the first semicircular cover 407 through the first steel pipe 403, then the first loop bar 302 drives the third transmission wheel 401 to transmit the fourth transmission wheel 402 to rotate, the fourth transmission wheel 402 drives the first steel pipe 403 to transmit the first semicircular cover 407 to rotate, so that the clean water ejected from the first semicircular cover 407 is uniformly ejected to the round surface part of the small container, and simultaneously the first steel pipe 403 drives the first rubber frame 408 to rotate, the first rubber frame 408 cleans the round surface of the small container, then the transmission component 2 drives the reagent disk to do up-and-down reciprocating motion with small amplitude, at this time, clean water is sprayed out from the four groups of first water spraying head groups 406 to the side wall of the small container through the first steel pipe 403, then the first steel pipe 403 drives the four groups of first brushes 405 to rotate, so that the inner wall of the small container is cleaned, in the process, the fourth electric push rod 4010 drives the first limiting cylinder 409 to do up-and-down reciprocating motion, so that the first limiting cylinder 409 is always in contact with the reagent disk, the cleaned water flows into the first limiting box 4012 on the first supporting frame 4011 through the first limiting cylinder 409, then the cleaned water flows into the first accommodating box 4017 through the second steel pipe 4013, so that the cleaned water flow splashes and is prevented from splashing onto the second sponge rod 4027, then the transmission component 2 stops driving the reagent disk to move, the sixth electric push rod 4028 drives the second support 4026 to move upwards, the second support 4026 drives the components associated with the second support to move upwards, in the process, the first telescopic hose 4019 is stretched, the second rubber rack 4023 is inserted into a container in the inner ring of the reagent disk, so that the second rubber rack 4023 is tightly attached to the inside of the large container, at this time, the second spur gear 4030 on the fourth transmission rod 4029 is meshed with the first spur gear 404, then the first steel pipe 403 drives the first spur gear 404 to drive the second spur gear 4030 to rotate, the second spur gear 4030 drives the third spur gear 4031 to drive the fourth steel pipe 4020 to rotate, the fourth steel pipe 4020 drives the second water jet head set 4021, the third water jet head set 4022 and the second rubber rack 4023 to rotate, at this time, water flow sequentially passes through the third steel pipe 4015, the first telescopic hose 4019 and the fourth steel pipe 4020 to be ejected from the plurality of second water jet head sets 4021 and the third water jet head set 4022, the water flow is sprayed to the side wall of the large container through the multiple groups of second water spray head groups 4021, the water flow is sprayed to the plane of the large container through the third water spray head groups 4022, so that the large container is cleaned through the second rubber frame 4023, the fifth electric push rod 4025 drives the second limiting cylinder 4024 to be in contact with the bottom of the reagent tray, so that the cleaned water is limited, then the sixth electric push rod 4028 drives the second supporting frame 4026 to move downwards to the original position, the second supporting frame 4026 drives the components associated with the second supporting frame 4026 to move downwards to the original position, then the transmission component 2 drives the reagent tray to move upwards to be separated from the pipe wall cleaning component 4, the transmission component 2 drives the reagent tray to rotate for a certain angle, so that the second small container is located at the initial position of the first small container, then the operation is repeated to clean the second small container, at the moment, the first sponge rod 4014 is inserted into the first small container to suck and remove the water completely, when the fourth small container is cleaned, the second large container is located at the initial position of the first large container, at the moment, the second sponge rod 4027 is inserted into the first large container to completely absorb moisture, small containers of the reagent tray are automatically cleaned and wiped one by one during use, and simultaneously, one large container is cleaned while every three small containers are cleaned, so that all containers on the reagent tray are cleaned, and the efficiency is greatly improved.
In the invention, a convex block is arranged on the outer ring surface of the first single gear 2010, and a plurality of groups of grooves are equidistantly arranged on the inner ring surface of the first rotating disc 2011.
When the first single gear 2010 rotates, the first rotating disk 2011 is driven to rotate in a pause mode.
According to the invention, high-density sponges are arranged on the opposite sides of the first sponge block 3014 and the second sponge block 3017, and bumps are arranged on the opposite sides of the two sponges at equal intervals.
The convex blocks can be respectively extruded into the gaps between the small containers on the outer ring of the reagent disk.
In the invention, the first rubber frame 408 is composed of a quarter ring and a long ring.
The circular ring part of the first rubber frame 408 can cover the circular surface part of the small container of the reagent disk.
In the invention, the two vertical strip-shaped blocks of the second rubber frame 4023 are arc blocks, and the lower parts of the two vertical blocks are both provided with a convex block.
The two arc blocks can be attached to the inner part of the large reagent tray container, and the two convex blocks can be attached to the chamfer of the opening of the large reagent tray container.
The embodiments described above are provided to enable persons skilled in the art to make or use the invention and that modifications or variations can be made to the embodiments described above by persons skilled in the art without departing from the inventive concept of the present invention, so that the scope of protection of the present invention is not limited by the embodiments described above but should be accorded the widest scope consistent with the innovative features set forth in the claims.

Claims (5)

1. A circumference is step by step type nucleic acid detection and is used reagent tray belt cleaning device, including chassis and control panel, its characteristic is, also include drive assembly, sidewall wash assembly and tube wall wash assembly; the underframe is connected with the transmission assembly; the bottom frame is connected with the side wall cleaning assembly; the underframe is connected with the pipe wall cleaning assembly; the chassis is connected with the control screen; the transmission assembly is connected with the side wall cleaning assembly; the side wall cleaning component is connected with the pipe wall cleaning component;
the transmission assembly comprises a first transmission rod, a first transmission wheel, a second transmission rod, a first bevel gear, a second bevel gear, a first electric push rod, a third bevel gear, a third transmission rod, a first single gear, a first rotary disc, a first limiting ring, a first multistage electric telescopic rod and a first electric sucker; the outer surface of the first transmission rod is fixedly connected with the first transmission wheel; the outer surface of the first transmission rod is rotationally connected with the bottom frame; the outer surface of the first transmission rod is connected with the side wall cleaning component; the first driving wheel is in transmission connection with the second driving wheel through a belt; the inner part of the second driving wheel is fixedly connected with a second driving rod; the outer surface of the second transmission rod is fixedly connected with the first bevel gear; the outer surface of the second transmission rod is rotatably connected with the underframe; a second bevel gear is arranged on the side edge of the first bevel gear; the inner part of the second bevel gear is fixedly connected with the first electric push rod; a third bevel gear is arranged on the side edge of the second bevel gear; the first electric push rod is fixedly connected with the underframe; the inner part of the third bevel gear is fixedly connected with a third transmission rod; the lower part of the third transmission rod is fixedly connected with the first single gear; the outer surface of the third transmission rod is rotatably connected with the underframe; the first single gear is meshed with the first rotating disc; the first turntable is in rotating connection with the first limiting ring; the lower part of the first rotating disc is fixedly connected with a first multistage electric telescopic rod; the first limiting ring is fixedly connected with the underframe; the first multistage electric telescopic rod is fixedly connected with the first electric sucker;
the side wall cleaning assembly comprises a first motor, a first loop bar, a first ridge bar, a first slide block, a first electric slide rail, a fourth bevel gear, a fifth bevel gear, a first bidirectional screw rod, a second slide block, a third slide block, a first guide rail block, a second electric push rod, a first linkage block, a first sponge block, a third electric push rod, a second linkage block and a second sponge block; the upper part of the first motor is fixedly connected with the first sleeve rod; the first motor is fixedly connected with the underframe; the inner part of the first sleeve rod is connected with the first prismatic rod; the outer surface of the first sleeve rod is rotatably connected with the underframe; the outer surface of the first sleeve rod is connected with the pipe wall cleaning assembly; the outer surface of the first prismatic rod is rotationally connected with the first sliding block; the outer surface of the first prismatic rod is fixedly connected with a fourth bevel gear; the first sliding block is in sliding connection with the first electric sliding rail; the first electric slide rail is fixedly connected with the underframe; a fifth bevel gear is arranged above the fourth bevel gear; the inner part of the fourth bevel gear is fixedly connected with the first transmission rod; the interior of the fifth bevel gear is fixedly connected with the first bidirectional screw rod; the outer surface of the first bidirectional screw rod is sequentially connected with the second sliding block and the third sliding block in a screwing manner; the outer surface of the first bidirectional screw rod is rotationally connected with the first guide rail block; the inside of the second sliding block is connected with the first guide rail block in a sliding way; the second sliding block is fixedly connected with a second electric push rod; the third slide block is connected with the first guide rail block in a sliding manner; the third sliding block is fixedly connected with a third electric push rod; the first guide rail block is fixedly connected with the bottom frame; the second electric push rod is fixedly connected with the first linkage block; the first linkage block is fixedly connected with the first sponge block; the third electric push rod is fixedly connected with the second linkage block; the second linkage block is fixedly connected with the second sponge block;
the pipe wall cleaning component comprises a third transmission wheel, a fourth transmission wheel, a first steel pipe, a first straight gear, a first brush, a first sprinkler head group, a first semicircular cover, a first rubber frame, a first limiting cylinder, a fourth electric push rod, a first support frame, a first limiting box, a second steel pipe, a first sponge rod, a third steel pipe, a first water pump, a first storage box, a first connecting block, a first telescopic hose, a fourth steel pipe, a second sprinkler head group, a third sprinkler head group, a second rubber frame, a second limiting cylinder, a fifth electric push rod, a second support frame, a second sponge rod, a sixth electric push rod, a fourth transmission rod, a second straight gear and a third straight gear; the third driving wheel is in transmission connection with the fourth driving wheel through a belt; the inner part of the third driving wheel is fixedly connected with the first sleeve rod; the inner part of the fourth driving wheel is fixedly connected with the first steel pipe; the outer surface of the first steel pipe is fixedly connected with the first straight gear; the outer surface of the first steel pipe is fixedly connected with the first brush; the outer surface of the first steel pipe is fixedly connected with the first water spraying head group; the upper part of the first steel pipe is fixedly connected with the first semicircular cover; the first steel pipe is fixedly connected with the first rubber frame; the outer surface of the first steel pipe is rotationally connected with the first support frame; the outer surface of the first steel pipe is rotatably connected with the first limiting box; the lower part of the first steel pipe is rotationally connected with the third steel pipe; a first limiting cylinder is arranged on the outer side of the first steel pipe; the first steel pipe is fixedly connected with the underframe; the first limiting cylinder is fixedly connected with the fourth electric push rod; the first limiting cylinder is connected with the first support frame in a sliding manner; the fourth electric push rod is fixedly connected with the first support frame; the first support frame is fixedly connected with the first limiting box; the first support frame is fixedly connected with the first sponge rod; the first support frame is fixedly connected with the underframe; the first limiting box is fixedly connected with the second steel pipe; the third steel pipe is fixedly connected with the first water pump; the outer surface of the third steel pipe is fixedly connected with the first connecting block; the third steel pipe is fixedly connected with the first flexible hose; the first water pump is fixedly connected with the first storage box; the first storage box is fixedly connected with the first connecting block; the lower part of the first storage box is fixedly connected with the underframe; the first flexible hose is rotatably connected with the fourth steel pipe; the outer surface of the upper part of the first telescopic hose is fixedly connected with the second support frame; the outer surface of the lower part of the fourth steel pipe is rotationally connected with the second support frame; the fourth steel pipe is fixedly connected with the second water spray head group; the fourth steel pipe is fixedly connected with the third water spray head group; the fourth steel pipe is fixedly connected with the second rubber frame; a second limiting cylinder is arranged on the outer side of the fourth steel pipe; the second limiting cylinder is fixedly connected with the fifth electric push rod; the second limiting cylinder is in sliding connection with the second support frame; the fifth electric push rod is fixedly connected with the second support frame; the second supporting frame is fixedly connected with the second sponge rod; the second support frame is fixedly connected with the sixth electric push rod; the second support frame is rotatably connected with the fourth transmission rod; the outer surface of the fourth transmission rod is fixedly connected with the second straight gear; the second spur gear is meshed with the third spur gear.
2. The apparatus for washing a reagent disk for use in circumferential stepwise nucleic acid detection as claimed in claim 1, wherein the first single gear has a projection on an outer circumferential surface thereof and the first rotary disk has a plurality of grooves on an inner circumferential surface thereof at equal intervals.
3. The circumferential step-by-step reagent disk cleaning device for nucleic acid detection according to claim 2, wherein the first sponge block and the second sponge block are provided with high-density sponges on opposite sides, and the two sponges are provided with projections on opposite sides at equal intervals.
4. The apparatus for washing reagent plates for nucleic acid detection according to claim 3, wherein the first rubber holder is composed of a quarter ring and a long ring.
5. The circumferential step-by-step reagent disk cleaning device for nucleic acid detection according to claim 4, wherein the two vertical elongated blocks of the second rubber frame are arc blocks, and a projection is provided at the lower part of each of the two vertical blocks.
CN202110266945.8A 2021-03-11 2021-03-11 Circumferential step-by-step type reagent disk cleaning device for nucleic acid detection Active CN113172011B (en)

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