CN113170739A - Mouse feeding cage for simulating weightless environment - Google Patents
Mouse feeding cage for simulating weightless environment Download PDFInfo
- Publication number
- CN113170739A CN113170739A CN202110612033.1A CN202110612033A CN113170739A CN 113170739 A CN113170739 A CN 113170739A CN 202110612033 A CN202110612033 A CN 202110612033A CN 113170739 A CN113170739 A CN 113170739A
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- China
- Prior art keywords
- cage
- simulating
- mouse
- feeding
- suspension
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- 239000000725 suspension Substances 0.000 claims abstract description 31
- 230000000384 rearing effect Effects 0.000 claims abstract description 16
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229910052802 copper Inorganic materials 0.000 claims abstract description 6
- 239000010949 copper Substances 0.000 claims abstract description 6
- 230000033228 biological regulation Effects 0.000 claims abstract description 5
- 238000005192 partition Methods 0.000 claims description 8
- 229910001220 stainless steel Inorganic materials 0.000 claims description 8
- 239000010935 stainless steel Substances 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 3
- 238000005339 levitation Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 13
- 238000011160 research Methods 0.000 abstract description 10
- 230000005484 gravity Effects 0.000 abstract description 9
- 230000008081 blood perfusion Effects 0.000 abstract description 5
- 238000004088 simulation Methods 0.000 abstract description 4
- 230000036544 posture Effects 0.000 description 9
- 230000009471 action Effects 0.000 description 3
- 230000005486 microgravity Effects 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000004580 weight loss Effects 0.000 description 2
- 206010065687 Bone loss Diseases 0.000 description 1
- 238000006124 Pilkington process Methods 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000031018 biological processes and functions Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000010072 bone remodeling Effects 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000013632 homeostatic process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000001144 postural effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000001846 repelling effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
- A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/035—Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Housing For Livestock And Birds (AREA)
Abstract
The invention discloses a mouse feeding cage for simulating a weightless environment, which consists of an electromagnet base, a feeding cage and a suspension assembly, wherein an electrified copper coil is embedded in the electromagnet base, and a power plug, a switch button and a current regulation knob are arranged on the outer side wall of the electromagnet base; the feeding cage is of a box body structure with an opening at the upper end, the feeding cage is arranged at the top end of the electromagnet base, a feeding opening is formed in one side wall of the feeding cage, and a placing frame is arranged in the feeding opening; the suspension assembly comprises a net-shaped top cover and a plurality of suspension magnets, the net-shaped top cover is placed at an opening in the upper end of the rearing cage, and a bundle of binding bands is arranged on each suspension magnet. The mouse cage for simulating the weightless environment has the characteristics of adjustable parameters and adjustable weightless degree; the posture problem caused by simulating weightlessness by the traditional tail suspension method can be solved, the influence of non-gravity factors such as blood perfusion and the like caused by the posture problem is solved, and the weightlessness simulation research can be better carried out.
Description
Technical Field
The invention relates to a mouse cage for simulating a weightless environment.
Background
With the progress of science and technology, space exploration has become an important field of human development. Astronauts lose the action of gravity in the outer space, and the weightless environment brings different influences on various tissues of the human body. Gravity is not negligible in the physical environment of the cell, and is essential for maintaining biological processes throughout most tissues of the body, and plays a crucial role in regulating bone remodeling and homeostasis, among other things. The weightless environment during space flight can lead to significant bone loss from weight bearing bones at a rate of about 1-2% per month. Therefore, how to overcome the gravity action on the ground surface to simulate the weightlessness environment is the premise and key for scientific researchers to carry out various weightlessness researches.
Methods for simulating a weightless environment include a tower falling method, a parabolic flight method, a water float method, a suspension method, an air suspension method, and the like. However, the application of the above methods in the biological field is greatly limited, which seriously hinders the progress of the research on weight loss. The tail suspension weightlessness animal model is the weightlessness model which is most applied in the field of biology at present, and simulates weightlessness or microgravity environment by suspending an animal tail. However, the obvious drawback is that this model changes the normal physiological posture of the animal, which introduces other irrelevant disturbing factors besides gravity, so that the reliability of the research results is greatly compromised. For example, postural changes affect blood perfusion, further altering the function and action of the tissue. The cause of the research results in this case is no longer the sole effect of gravity.
How to construct a weightlessness model on the premise of not changing postures and introducing other interference factors is an urgent problem to be solved in the process of researching weightlessness.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a mouse cage for simulating a weightless environment, which has the characteristics of adjustable parameters and adjustable weightlessness degree; the posture problem caused by simulating weightlessness by the traditional tail suspension method can be solved, the influence of non-gravity factors such as blood perfusion and the like caused by the posture problem is solved, and the weightlessness simulation research can be better carried out.
The technical scheme for realizing the purpose is as follows: a mouse rearging cage for simulating weightless environment comprises an electromagnet base, a rearging cage and a suspension assembly, wherein:
the electromagnet base is of a cuboid structure, an electrified copper coil is embedded in the electromagnet base, and a power plug, a switch button and a current regulation knob are arranged on the outer side wall of the electromagnet base;
the feeding cage is of a box body structure with an opening at the upper end, the feeding cage is arranged at the top end of the electromagnet base, a feeding opening is formed in one side wall of the feeding cage, and a placing frame is arranged in the feeding opening;
the suspension assembly comprises a net-shaped top cover and a plurality of suspension magnets, the net-shaped top cover is placed at an opening in the upper end of the rearing cage, a bundle of binding bands is arranged on each suspension magnet, one end of each binding band penetrates through the net-shaped top cover and then is connected with the suspension magnets, and the other end of each binding band is connected with a mouse.
The mouse feeding cage for simulating the weightless environment is characterized in that the distance between the placing rack and the top end of the feeding cage is equal to the distance between the placing rack and the bottom end of the feeding cage.
The mouse feeding cage for simulating the weightless environment is made of plastic materials; the placing frame adopts a stainless steel mesh structure; the net-shaped top cover is made of stainless steel.
The mouse feeding cage for simulating the weightless environment is characterized in that a partition plate is vertically arranged in the placing frame, the placing frame is divided into two parts by the partition plate, one part is a water bottle placing part, and the other part is a fodder placing part.
The mouse feeding cage for simulating the weightless environment is characterized in that the placing rack is in a right-angle shape.
The mouse cage for simulating the weightless environment is characterized in that the suspension magnet is square.
The mouse feeding cage for simulating the weightless environment is characterized in that a base partition plate is arranged at the top end of the electromagnet base.
The mouse cage for simulating the weightless environment has the following advantages:
(1) the method has the characteristics of adjustable parameters and adjustable weightlessness degree;
(2) the mouse can move freely to the maximum extent, and can better simulate the normal movement of astronauts in the space, so that the research result is more reliable and has more practical application significance;
(3) the posture problem caused by simulating weightlessness by the traditional tail suspension method can be solved, the influence of non-gravity factors such as blood perfusion and the like caused by the posture problem is solved, and the weightlessness simulation research can be better carried out.
Drawings
Fig. 1 is a perspective view (front view direction) of a mouse cage for simulating a weightless environment according to the present invention;
fig. 2 is a perspective view (rear view direction) of a mouse cage for simulating a weightless environment according to the present invention;
fig. 3 is an exploded view of the mouse cage for simulating a weightless environment according to the present invention.
Detailed Description
In order that those skilled in the art will better understand the technical solution of the present invention, the following detailed description is given with reference to the accompanying drawings:
referring to fig. 1, 2 and 3, a rat cage for simulating weightless environment according to the preferred embodiment of the present invention is composed of an electromagnet base 1, a cage 2 and a suspension assembly.
Electromagnet base 1 is the cuboid structure, and electromagnet base 1's inside is inlayed and is had circular telegram copper coil 11, is provided with power plug 12, shift knob 13 and current regulation and control knob 14 on electromagnet base 1's the lateral wall. The power plug 12 is connected with the electrified copper coil 11, and a switch button 13 and a current regulation knob 14 are arranged on a connecting line between the power plug 12 and the electrified copper coil 11.
The rearing cage 2 is of a box body structure with an opening at the upper end, and the rearing cage 2 is made of plastic materials; the rearing cage 2 is arranged on the top end of the electromagnet base 1, and a base partition plate 15 is arranged on the top end of the electromagnet base 1. A feeding opening 21 is formed in one side wall of the rearing cage 2, and a placing frame 22 is arranged in the feeding opening 21; the placing frame 22 adopts a stainless steel mesh structure; the rack 22 is in a right-angle shape. A partition plate 23 is vertically arranged in the placing frame 22, and the placing frame is divided into two parts by the partition plate 23, wherein one part is a water bottle placing part, and the other part is a feed placing part. The distance between the placing frame 22 and the top end of the rearing cage 2 is equal to the distance between the placing frame 22 and the bottom end of the rearing cage 2.
The suspension assembly comprises a mesh top cover 31 and a plurality of suspension magnets 32, wherein the mesh top cover 31 is made of stainless steel. The net-shaped top cover 31 is placed on the upper opening of the rearing cage 2, a binding belt 33 is arranged on each suspension magnet 32, one end of the binding belt 33 penetrates through the net-shaped top cover 31 and then is connected with the suspension magnet 32, and the other end of the binding belt 33 is connected with a mouse, so that the suspension magnet 32 can slide freely along the net-shaped top cover 31 under the driving of the binding belt 33. The levitation magnet 32 has a square shape.
The mouse cage for simulating the weightless environment can select the following specific dimensions: the electromagnet base 1 is 485mm long, 390mm wide and 80mm high. The length of the rearing cage 2 is 485mm, the width is 390mm, and the height is 200 mm. The stainless steel mesh interval of rack 22 is 15mm, and the width of water bottle portion of placing is 80mm, and the width of fodder portion of placing is 300 mm. The length of the mesh top cover 31 is 485mm, the width is 390mm, and the distance between the stainless steel mesh strips is 15 mm.
When the mouse cage for simulating the weightless environment is used, the weight of each mouse is weighed, and the suspension magnets 32 with corresponding sizes are selected according to the weight and are bound. The tying band 33 is previously passed through the mesh top cover 31 before tying. After the completion of the binding, the suspended magnet 32 and the net-like top cover 31 in which the rats are bound are placed on the cage 2. The power is switched on through the power plug 12, the switch button 13 is turned on, and the current is adjusted through the current adjusting knob 14, so that the mouse can suspend or lightly contact the bottom of the rearing cage 2. The length of the tying band 33 is adjusted so that each mouse with different weights is in the same microgravity or weightless environment. Water bottles and feed are placed on the placing rack 22 of the rearing cage 2, and normal rearing can be performed. In the process of the weightlessness study, the current can be adjusted by the current adjusting knob 14 to conveniently and rapidly change the weightlessness parameters, so that the weightlessness study can be better completed. The influence of weight change on weightlessness of each mouse in the same rearing cage needs to be regularly observed during rearing, and current adjustment or binding length adjustment needs to be carried out in time to keep the front and rear weightlessness parameters uniform.
According to the mouse cage for simulating the weightless environment, the electromagnet suspension principle is utilized, the magnet is bound on the back of a mouse, the electromagnet is arranged at the bottom, and the suspension platform with the same poles repelling each other is constructed, so that the normal physiological posture of the mouse is not changed by the weightless model, and the mouse can be allowed to perform free physiological activities under the weightless or microgravity condition; therefore, the invention eliminates other factors to be interfered more strictly, and is beneficial to the development progress of the weight loss research.
In conclusion, the mouse cage for simulating the weightless environment has the characteristics of adjustable parameters and adjustable weightless degree; the posture problem caused by simulating weightlessness by the traditional tail suspension method can be solved, the influence of non-gravity factors such as blood perfusion and the like caused by the posture problem is solved, and the weightlessness simulation research can be better carried out.
It should be understood by those skilled in the art that the above embodiments are only for illustrating the present invention and are not to be used as a limitation of the present invention, and that changes and modifications to the above described embodiments are within the scope of the claims of the present invention as long as they are within the spirit and scope of the present invention.
Claims (7)
1. The utility model provides a mouse rearging cage for simulating weightlessness environment which characterized in that comprises electro-magnet base, rearging cage and suspension subassembly, wherein:
the electromagnet base is of a cuboid structure, an electrified copper coil is embedded in the electromagnet base, and a power plug, a switch button and a current regulation knob are arranged on the outer side wall of the electromagnet base;
the feeding cage is of a box body structure with an opening at the upper end, the feeding cage is arranged at the top end of the electromagnet base, a feeding opening is formed in one side wall of the feeding cage, and a placing frame is arranged in the feeding opening;
the suspension assembly comprises a net-shaped top cover and a plurality of suspension magnets, the net-shaped top cover is placed at an opening in the upper end of the rearing cage, a bundle of binding bands is arranged on each suspension magnet, one end of each binding band penetrates through the net-shaped top cover and then is connected with the suspension magnets, and the other end of each binding band is connected with a mouse.
2. A mouse cage for simulating a weightless environment according to claim 1, characterized in that the distance between the rack and the top end of the cage is equal to the distance between the rack and the bottom end of the cage.
3. A mouse cage for simulating a weightless environment according to claim 1, wherein the cage is made of a plastic material; the placing frame adopts a stainless steel mesh structure; the net-shaped top cover is made of stainless steel.
4. A mouse cage for simulating weightless environment according to claim 1, characterized in that a partition board is vertically arranged in the rack, and divides the rack into two parts, one part is a water bottle placing part, and the other part is a feed placing part.
5. A mouse cage according to claim 1, wherein the rack is right-angled.
6. A mouse cage for simulating a weightless environment according to claim 1, wherein the levitation magnet has a square shape.
7. A mouse cage according to claim 1, wherein a base partition is provided on the top of the electromagnet base.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110612033.1A CN113170739A (en) | 2021-06-01 | 2021-06-01 | Mouse feeding cage for simulating weightless environment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110612033.1A CN113170739A (en) | 2021-06-01 | 2021-06-01 | Mouse feeding cage for simulating weightless environment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113170739A true CN113170739A (en) | 2021-07-27 |
Family
ID=76927314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110612033.1A Pending CN113170739A (en) | 2021-06-01 | 2021-06-01 | Mouse feeding cage for simulating weightless environment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113170739A (en) |
-
2021
- 2021-06-01 CN CN202110612033.1A patent/CN113170739A/en active Pending
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