CN113163846B - 液体尼古丁制剂 - Google Patents

液体尼古丁制剂 Download PDF

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Publication number
CN113163846B
CN113163846B CN201980079924.6A CN201980079924A CN113163846B CN 113163846 B CN113163846 B CN 113163846B CN 201980079924 A CN201980079924 A CN 201980079924A CN 113163846 B CN113163846 B CN 113163846B
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CN
China
Prior art keywords
water
liquid nicotine
nicotine formulation
weight
equal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201980079924.6A
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English (en)
Chinese (zh)
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CN113163846A (zh
Inventor
J-P·沙勒
A·维亚尔诺兹-比塞
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Philip Morris Products SA
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Philip Morris Products SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of CN113163846A publication Critical patent/CN113163846A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/05—Devices without heating means
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/42—Cartridges or containers for inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/46—Shape or structure of electric heating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)
CN201980079924.6A 2018-12-31 2019-12-31 液体尼古丁制剂 Active CN113163846B (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
EP18215966.5 2018-12-31
EP18215966 2018-12-31
EP18215976 2018-12-31
EP18215976.4 2018-12-31
EP18215969 2018-12-31
EP18215969.9 2018-12-31
EP18215964.0 2018-12-31
EP18215964 2018-12-31
EP18215983 2018-12-31
EP18215983.0 2018-12-31
PCT/EP2019/087198 WO2020141180A1 (en) 2018-12-31 2019-12-31 Liquid nicotine formulation

Publications (2)

Publication Number Publication Date
CN113163846A CN113163846A (zh) 2021-07-23
CN113163846B true CN113163846B (zh) 2023-04-28

Family

ID=69104449

Family Applications (5)

Application Number Title Priority Date Filing Date
CN201980079924.6A Active CN113163846B (zh) 2018-12-31 2019-12-31 液体尼古丁制剂
CN201980079569.2A Active CN113163845B (zh) 2018-12-31 2019-12-31 包含部分水溶性溶剂的液体尼古丁制剂
CN201980079953.2A Active CN113163848B (zh) 2018-12-31 2019-12-31 低粘度液体尼古丁制剂
CN201980079943.9A Active CN113163847B (zh) 2018-12-31 2019-12-31 包含水不混溶性溶剂的液体尼古丁制剂
CN201980080351.9A Active CN113242696B (zh) 2018-12-31 2019-12-31 液体尼古丁制剂

Family Applications After (4)

Application Number Title Priority Date Filing Date
CN201980079569.2A Active CN113163845B (zh) 2018-12-31 2019-12-31 包含部分水溶性溶剂的液体尼古丁制剂
CN201980079953.2A Active CN113163848B (zh) 2018-12-31 2019-12-31 低粘度液体尼古丁制剂
CN201980079943.9A Active CN113163847B (zh) 2018-12-31 2019-12-31 包含水不混溶性溶剂的液体尼古丁制剂
CN201980080351.9A Active CN113242696B (zh) 2018-12-31 2019-12-31 液体尼古丁制剂

Country Status (11)

Country Link
US (5) US20220071270A1 (OSRAM)
EP (5) EP3905898B1 (OSRAM)
JP (5) JP7590324B2 (OSRAM)
KR (5) KR102901539B1 (OSRAM)
CN (5) CN113163846B (OSRAM)
BR (3) BR112021010593A2 (OSRAM)
ES (2) ES2980261T3 (OSRAM)
MX (5) MX2021007625A (OSRAM)
PL (2) PL3905900T3 (OSRAM)
UA (5) UA129122C2 (OSRAM)
WO (5) WO2020141180A1 (OSRAM)

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CN113164610A (zh) 2018-12-28 2021-07-23 菲利普莫里斯生产公司 包含低摩尔质量金属盐的液体尼古丁制剂
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IT202100027086A1 (it) * 2021-10-21 2023-04-21 Alberto Patarchi Erogatore portatile per il trattamento o la prevenzione di un’infezione o di una patologia causata da un virus
CN113912585B (zh) * 2021-11-09 2023-02-24 深圳萨特瓦生物科技有限公司 复合尼古丁盐及其制备方法与应用、电子烟油及电子烟
CN116235996A (zh) * 2021-12-07 2023-06-09 深圳雾芯科技有限公司 电子烟液及包含其的雾化装置
KR20240012197A (ko) * 2022-07-20 2024-01-29 주식회사 케이티앤지 표면파 아토마이저에 사용하기 위한 액상형 흡입제형, 이를 포함하는 카트리지 및 에어로졸 생성장치
KR102872477B1 (ko) * 2022-08-10 2025-10-20 주식회사 케이티앤지 니코틴 흡입성 조성물 및 이를 포함하는 에어로졸 발생 장치 및 시스템
KR102885439B1 (ko) * 2022-10-07 2025-11-17 주식회사 케이티앤지 에어로졸 흡입기용 액상 조성물
CN117204598A (zh) * 2023-07-05 2023-12-12 深圳梵活生命科学股份有限公司 一种应用于雾化器可缓解烟瘾的雾化液
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Also Published As

Publication number Publication date
JP7590324B2 (ja) 2024-11-26
CN113163848A (zh) 2021-07-23
CN113242696B (zh) 2023-04-28
JP2022516149A (ja) 2022-02-24
EP3905900B1 (en) 2024-05-15
UA129018C2 (uk) 2024-12-25
KR20210108394A (ko) 2021-09-02
EP3905898A1 (en) 2021-11-10
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