CN113069408A - Opsonin formula and preparation method - Google Patents
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Abstract
The invention relates to the technical field of opsonin, in particular to an opsonin formula and a preparation method thereof, wherein the opsonin formula comprises the following components in percentage by mass: 55-85% of phase A, 1.5-8.5% of phase B, 12-28% of phase C and 0.2-1.4% of phase D, and has the effects of caring and treating skin, repairing subcutaneous normal cells of skin, and moistening skin.
Description
Technical Field
The invention relates to the technical field of opsonins, in particular to an opsonin formula and a preparation method thereof.
Background
Along with the improvement of living standard of people, the requirements of people on the skin of the people are higher and higher on the premise of meeting the living demands of materials, particularly the requirements of people on the appearance are higher and higher, so that the requirements of people on the skin of the face are higher and higher. The invention relates to a problem of skin care for the face skin with problems, and therefore, the invention aims to solve the problem of how to realize the combination of treatment and care for the face skin to realize the repair and care of the skin.
Disclosure of Invention
The invention aims to provide a formula of an opsonin and a preparation method thereof aiming at the defects and the shortages of the prior art.
The invention relates to a conditioner formula which comprises the following components in percentage by mass: 55-85% of phase A, 1.5-8.5% of phase B, 12-28% of phase C and 0.2-1.4% of phase D;
wherein: the phase A comprises the following components in percentage by mass: 55-75% of water, 3-12% of glycerol, 2-8% of propylene glycol, 0.1-0.7% of carbomer, 0.05-0.5% of hydroxyethyl cellulose, 0.05-0.5% of methyl hydroxybenzoate, 0.1-0.6% of allantoin and 0.01-0.08% of sodium hyaluronate;
wherein: the phase B comprises the following components in percentage by mass: 0.5-4% of panthenol, 0.5-4% of trehalose and 0.1-0.7% of hydroxyproline;
wherein: the phase C comprises the following components in percentage by mass: 1-3% of glucan, 1-6% of nicotinamide, 10.5-4% of oligopeptide, 80.5-4% of acetyl hexapeptide, 1-9% of peony root extract, 0.5-4% of lactobacillus/soybean milk fermentation product filtrate, 0.2-2.5% of folic acid and 0.5-5.5% of bacillus/soybean fermentation product extract;
wherein: the phase D comprises the following components in percentage by mass: 0.1 to 0.9 percent of hexanediol, 0.02 to 0.4 percent of chlorphenesin and 0.05 to 0.5 percent of hydrogenated castor oil.
A method for preparing opsonin comprises:
the method comprises the following steps: adding phase A into an emulsifying pot, stirring and heating to about 85 ℃, and homogenizing in vacuum for 1min until the material is completely dissolved;
step two: stirring, keeping the temperature for 30min, and cooling;
step three: cooling to 55 deg.C, adding phase B, stirring, cooling to 45 deg.C, sequentially adding phase C and phase D, and stirring;
step four: and after sampling, detecting, and discharging after the product is qualified.
Further, the opsonin formula comprises the following components in percentage by mass: 74.8% of phase A, 4.4% of phase B, 20% of phase C and 0.8% of phase D.
Further, the opsonin formula comprises the following components in percentage by mass: 70.8% of phase A, 5.4% of phase B, 23% of phase C and 1.8% of phase D.
Further, the opsonin formula comprises the following components in percentage by mass: 76.8% of phase A, 4.1% of phase B, 18% of phase C and 1.1% of phase D.
Further, the opsonin formula comprises the following components in percentage by mass: 72.8% of phase A, 3.4% of phase B, 22% of phase C and 1.8% of phase D.
The working principle of the invention is as follows:
the invention has the beneficial effects that: the opsonin formula and the preparation method provided by the invention have the effects of caring skin, performing physical therapy on the skin, repairing subcutaneous normal cells of the skin and enabling the skin to be smooth, bright and white.
Detailed Description
The present invention will be described in detail with reference to specific examples, wherein the exemplary examples and descriptions are provided only for explaining the present invention and are not intended to limit the present invention.
The opsonin formula and the preparation method of the opsonin formula according to the specific embodiment comprise the following components in percentage by mass: 55-85% of phase A, 1.5-8.5% of phase B, 12-28% of phase C and 0.2-1.4% of phase D;
wherein: the phase A comprises the following components in percentage by mass: 55-75% of water, 3-12% of glycerol, 2-8% of propylene glycol, 0.1-0.7% of carbomer, 0.05-0.5% of hydroxyethyl cellulose, 0.05-0.5% of methyl hydroxybenzoate, 0.1-0.6% of allantoin and 0.01-0.08% of sodium hyaluronate;
wherein: the phase B comprises the following components in percentage by mass: 0.5-4% of panthenol, 0.5-4% of trehalose and 0.1-0.7% of hydroxyproline;
wherein: the phase C comprises the following components in percentage by mass: 1-3% of glucan, 1-6% of nicotinamide, 10.5-4% of oligopeptide, 80.5-4% of acetyl hexapeptide, 1-9% of peony root extract, 0.5-4% of lactobacillus/soybean milk fermentation product filtrate, 0.2-2.5% of folic acid and 0.5-5.5% of bacillus/soybean fermentation product extract;
wherein: the phase D comprises the following components in percentage by mass: 0.1 to 0.9 percent of hexanediol, 0.02 to 0.4 percent of chlorphenesin and 0.05 to 0.5 percent of hydrogenated castor oil.
A method for preparing opsonin comprises:
the method comprises the following steps: adding phase A into an emulsifying pot, stirring and heating to about 85 ℃, and homogenizing in vacuum for 1min until the material is completely dissolved;
step two: stirring, keeping the temperature for 30min, and cooling;
step three: cooling to 55 deg.C, adding phase B, stirring, cooling to 45 deg.C, sequentially adding phase C and phase D, and stirring;
step four: and after sampling, detecting, and discharging after the product is qualified.
Further, the opsonin formula comprises the following components in percentage by mass: 74.8% of phase A, 4.4% of phase B, 20% of phase C and 0.8% of phase D.
Further, the opsonin formula comprises the following components in percentage by mass: 70.8% of phase A, 5.4% of phase B, 23% of phase C and 1.8% of phase D.
Further, the opsonin formula comprises the following components in percentage by mass: 76.8% of phase A, 4.1% of phase B, 18% of phase C and 1.1% of phase D.
Further, the opsonin formula comprises the following components in percentage by mass: 72.8% of phase A, 3.4% of phase B, 22% of phase C and 1.8% of phase D.
The working principle of the invention is as follows:
the present invention is further illustrated by specific examples:
the formula of the conditioner comprises the following components in percentage by mass: 74.8% of phase A, 4.4% of phase B, 20% of phase C and 0.8% of phase D;
wherein: the phase A comprises the following components in percentage by mass: 60.65% of water, 8% of glycerol, 5% of propylene glycol, 0.4% of carbomer, 0.2% of hydroxyethyl cellulose, 0.2% of methylparaben, 0.3% of allantoin and 0.05% of sodium hyaluronate;
wherein: the phase B comprises the following components in percentage by mass: 2% of panthenol, 2% of trehalose and 0.4% of hydroxyproline;
wherein: the phase C comprises the following components in percentage by mass: 2% of glucan, 3% of nicotinamide, 12% of oligopeptide, 82% of acetyl hexapeptide, 5% of peony root extract, 2% of lactobacillus/soybean milk fermentation product filtrate, 1% of folic acid and 3% of bacillus/soybean fermentation product extract;
wherein: the phase D comprises the following components in percentage by mass: 0.5 percent of hexanediol, 0.1 percent of chlorphenesin and 0.2 percent of hydrogenated castor oil.
The effects of the components of the invention are as follows:
the function of the glycerol is as follows: moistening, moistening and lubricating intestinal tract.
The function of the propylene glycol is as follows: moisturizing and promoting the penetration of active ingredients of the cosmetic into the skin. Propylene glycol is a transparent, colorless, viscous chemical agent, is basically harmless to the skin, and is added to many cosmetics; for example, the frequently used makeup removing milk is added with propylene glycol, is a common moisturizing material in the makeup removing milk, and has the effect of assisting water molecules to dissolve dirt on the face and preventing the skin from being rapidly dried in the makeup removing process.
The carbomer has the functions of: generally has skin protecting effect, and helps prevent anaphylaxis, reduces irritation substances, and helps prevent ultraviolet rays.
The function of the hydroxyethyl cellulose is as follows: has surface activity, thickening, suspending, binding, emulsifying, film forming, dispersing, water retaining and protecting effects in solid and liquid preparations of medicines.
The function of the methyl hydroxybenzoate is as follows: can be used as antiseptic for organic synthetic food, cosmetics and medicine, and can also be used as feed antiseptic. It can be added into cosmetic for inhibiting and smoothing skin,
the action functions of allantoin are as follows: is a derivative of uric acid, which acts as an antioxidant and produces allantoin after the action of free radicals. Research shows that allantoin can directly act on keratin of skin, increase and promote hydration ability of stratum corneum and reduce water loss.
The sodium hyaluronate has the functions of: has moisture keeping and nourishing effects. Sodium hyaluronate has a moisturizing effect, the most important effect of sodium hyaluronate in cosmetics is the moisturizing effect, and compared with other moisturizing agents, the influence of the relative humidity of the surrounding environment on the moisturizing effect of sodium hyaluronate is small. The second is the nutrition effect, sodium hyaluronate is the inherent biological substance of the skin, exogenous sodium hyaluronate is the endogenous supplement of the skin, and smaller sodium hyaluronate can penetrate into the epidermal layer of the skin to promote the supply of skin nutrition and the excretion of waste, thereby preventing skin aging and playing the roles of beautifying and nourishing the face.
The action functions of panthenol are: the skin care product is a deeply penetrating moisturizer, which can stimulate the growth of epidermal cells and can be easily absorbed, penetrated and penetrated into stratum corneum on the skin surface. In short, it gives skin gloss, prevents roughness and aging.
The action functions of trehalose are as follows: the low-temperature-resistant water-soluble organic acid can be added into cosmetics to reduce the freezing point of a water phase, thereby improving the low-temperature stability of the product. In addition, the prevention of osteoporosis is one of the important effects of trehalose, and the active ingredients contained in the trehalose can inhibit the decomposition of ossein in a human body and can accelerate the absorption and utilization of various nutrient components such as trace elements of calcium, phosphorus and the like by the human body.
The function of hydroxyproline is as follows: is one of the main components of collagen tissue, is the amino acid which is peculiar to collagen and accounts for about 13 percent of the total amount of the amino acid of the collagen. Collagen is the most abundant protein in the body, and accounts for about 1/3 total proteins in human body
The action function of glucan is: enhancing the self-protection capability of the skin, improving the immunity of the skin and removing free radicals; activating skin cells, promoting collagen synthesis and improving skin elasticity; excellent antiallergic effect.
The action function of nicotinamide is: anti-arrhythmia, improving vascular endothelial function, stimulating beta cell regeneration, anti-inflammation, etc.; is mainly used for preventing and treating pellagra, stomatitis, glossitis, sick sinus syndrome, atrioventricular block and other problems in clinic
The function of oligopeptide-1 is as follows: the oligopeptide-1 is a synthetic peptide consisting of 3 amino acids such as glycine, histidine, lysine and the like, the amino acids have good moisture retention, permeability and compatibility, and in skin care products, the amino acids are usually used as the moisture retention agents, so that the natural amino acids in the skin can be supplemented, and the moisture retention of stratum corneum can be helped.
The function of acetyl hexapeptide is: is a bioactive polypeptide (acetyl hexapeptide-3), which can reduce existing facial wrinkles and effectively prevent new wrinkles.
The action function of the peony root extract is as follows: the effective component paeoniflorin has inhibitory effect on some pathogenic bacteria and fungi. Peony extract has effects of inhibiting elastase, scavenging free radicals, inhibiting nitrogen oxide production, and promoting cathepsin activity.
The function of the lactobacillus/soybean milk fermentation product filtrate is as follows: the main function of the cosmetic and the skin care product is a humectant.
The function of folic acid is as follows: has the function of promoting the maturation of the juvenile cells in the bone marrow and has high-efficiency effect on repairing the skin: not only can enhance the moisture retention capacity of the skin, but also can supplement nutrient substances required by the skin.
The function of the bacillus/soybean fermentation product extract is as follows: the product has antioxidant effect, and can be used as skin conditioner and humectant in cosmetics and skin care products.
The action functions of the hexanediol are as follows: 1, 2-pentanediol is a relatively less irritating, safer additive. Has extremely high hygroscopicity and water retention, and is therefore the most commonly used humectant in cosmetics.
The chlorphenesin has the functions of: the effect on the skin is sterilization.
The function of the hydrogenated castor oil is as follows: is a solvent in cosmetics and is used as a softening agent in cosmetics and skin care products.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention, and all equivalent changes and modifications made based on the features and principles described in the claims of the present invention are included in the scope of the present invention.
Claims (5)
1. A opsonin formula and a preparation method are characterized in that: the components by mass percentage are as follows: 55-85% of phase A, 1.5-8.5% of phase B, 12-28% of phase C and 0.2-1.4% of phase D;
wherein: the phase A comprises the following components in percentage by mass: 55-75% of water, 3-12% of glycerol, 2-8% of propylene glycol, 0.1-0.7% of carbomer, 0.05-0.5% of hydroxyethyl cellulose, 0.05-0.5% of methyl hydroxybenzoate, 0.1-0.6% of allantoin and 0.01-0.08% of sodium hyaluronate;
wherein: the phase B comprises the following components in percentage by mass: 0.5-4% of panthenol, 0.5-4% of trehalose and 0.1-0.7% of hydroxyproline;
wherein: the phase C comprises the following components in percentage by mass: 1-3% of glucan, 1-6% of nicotinamide, 10.5-4% of oligopeptide, 80.5-4% of acetyl hexapeptide, 1-9% of peony root extract, 0.5-4% of lactobacillus/soybean milk fermentation product filtrate, 0.2-2.5% of folic acid and 0.5-5.5% of bacillus/soybean fermentation product extract;
wherein: the phase D comprises the following components in percentage by mass: 0.1 to 0.9 percent of hexanediol, 0.02 to 0.4 percent of chlorphenesin and 0.05 to 0.5 percent of hydrogenated castor oil.
2. A method for preparing opsonin comprises: the method is characterized by comprising the following steps:
the method comprises the following steps: adding phase A into an emulsifying pot, stirring and heating to about 85 ℃, and homogenizing in vacuum for 1min until the material is completely dissolved;
step two: stirring, keeping the temperature for 30min, and cooling;
step three: cooling to 55 deg.C, adding phase B, stirring, cooling to 45 deg.C, sequentially adding phase C and phase D, and stirring;
step four: and after sampling, detecting, and discharging after the product is qualified.
3. An opsonin formulation and method of making according to claim 1, wherein: the formula of the conditioner comprises the following components in percentage by mass: 74.8% of phase A, 4.4% of phase B, 20% of phase C and 0.8% of phase D.
Further, the opsonin formula comprises the following components in percentage by mass: 70.8% of phase A, 5.4% of phase B, 23% of phase C and 1.8% of phase D.
4. An opsonin formulation and method of making according to claim 1, wherein: the formula of the conditioner comprises the following components in percentage by mass: 76.8% of phase A, 4.1% of phase B, 18% of phase C and 1.1% of phase D.
5. An opsonin formulation and method of making according to claim 1, wherein: the formula of the conditioner comprises the following components in percentage by mass: 72.8% of phase A, 3.4% of phase B, 22% of phase C and 1.8% of phase D.
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CN202110361224.5A CN113069408A (en) | 2021-04-02 | 2021-04-02 | Opsonin formula and preparation method |
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CN202110361224.5A Withdrawn CN113069408A (en) | 2021-04-02 | 2021-04-02 | Opsonin formula and preparation method |
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