CN113057261A - Acid preparation composition for improving production performance of meat pigeons, preparation method and application - Google Patents
Acid preparation composition for improving production performance of meat pigeons, preparation method and application Download PDFInfo
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Abstract
The invention provides an acid preparation composition for improving the production performance of meat pigeons, a preparation method and application thereof, wherein the acid preparation composition comprises a coating wall material, a binder, a Tween 80 emulsifier, silicon dioxide, an organic acid compound, an essential oil compound, nojirimycin (mulberry leaf extract), a blood-enriching compound and white carbon black. The invention can quickly reduce the pH value of the stomach, promote the pepsinogen to be converted into pepsin, and improve the activity of the pepsin, thereby improving the digestion of nutrient substances such as protein and the like; on the other hand, essential oils such as carvacrol and cinnamaldehyde have the effects of accelerating the surface maturation of intestinal villi and the renewal rate of intestinal epithelial cells, promoting the maturation of an endothelial layer of a digestive tract, stimulating the development of the intestinal villi, increasing the digestion and absorption area, and promoting the secretion of various digestive enzymes in the intestinal tract, so that the digestion and absorption functions of the meat pigeons are improved.
Description
Technical Field
The invention belongs to the technical field of meat pigeon feeds, relates to an ingredient of a main material of a meat pigeon feed, and particularly relates to an acid preparation composition for improving the production performance of meat pigeons, a preparation method and application thereof.
Background
According to modern scientific research, the meat of the meat pigeon is exquisite and delicious, has high nutritional value, contains high content of protein and energy in meat food, is a natural high-grade nutrient and tonic, has the saying that one pigeon wins nine chickens since ancient times in China, and is more and more favored by consumers due to special high economic and high nutritional health-care values. According to statistics, the stock of the breeding pigeons in China in 2018 reaches 4145.6 ten thousand pairs, the young pigeons are born 6.43 million annually, the meat yield of the pigeons is 25.7 ten thousand tons, and according to relevant statistics, the young pigeons are required to exceed 10 million annually in Shanghai, Guangdong, Hainan and Hongkong Australian regions. The consumption of young pigeons in other big cities is over 1000 thousands, and the export volume is greatly increased in recent years along with the increasing demand of the international market.
With the increase of the demand of the meat pigeons, the scale breeding is more and more, the industrialization is continuously improved, and the pigeon raising industry is continuously developed. With the rapid development of the pigeon raising industry, pigeon diseases are increasing day by day, particularly, the growth performance of the meat pigeons is seriously affected by intestinal diseases, and the pathogenic bacteria causing the intestinal diseases of the meat pigeons mainly comprise the following parts: coccidiosis, salmonella, pasteurella, escherichia coli, parasites and the like, and the pathogenic bacteria often cause intestinal inflammation of the meat pigeons. Enteritis is a disease which is easy to occur and common to the pigeons, occurs all the year round and is the first killer which affects the health of the meat pigeons. At present, the method for preventing, controlling and treating enteritis is mainly to add antibiotics in feed or drinking water. The use of antibiotics in excess often has many negative effects on humans and the environment:
1. toxic effects
Animals use antibiotics, and some antibiotics may remain in the body. The animal products with serious overproof aminoglycoside antibiotics taken for a long time can cause nephrotoxicity and ototoxicity, the nephrotoxicity mainly damages renal tubular epithelial cells, proteinuria and hematuria occur, and renal hypofunction occurs in serious cases; ototoxicity is mainly manifested by vestibular dysfunction and cochlear nerve damage. Long-term intake of livestock products containing chloramphenicol residues can cause aplastic anemia.
2 drug resistance
The residue of antibiotics in animal products may cause drug resistance of animal pathogenic bacteria, drug resistance genes can be transmitted among bacteria through transformation, transduction, conjugation, translocation and the like, and the drug resistance genes can also be diffused through food chains and other ways, so that the drug resistance genes of the bacteria are mutually transmitted among bacteria in people, bacteria in animal groups and bacteria in ecological systems, and thus, the drug resistance of pathogenic bacteria (such as salmonella, escherichia coli, enterococcus and the like) is increased, the treatment failure of infectious diseases of human beings and animals is caused, and the health of the human beings is damaged.
3 disruption of the microecological balance in the body
Harmful pathogenic microorganisms exist in intestinal tracts of livestock and poultry, and beneficial microorganisms such as lactobacillus and bifidobacterium grow in the intestinal tracts. Normally, the microbial flora in the body is in a state of equilibrium with each other. The abuse of antibiotics can inhibit or kill pathogenic microorganisms and beneficial bacteria in vivo, destroy microecological balance in vivo, and cause morbidity or mortality of animals.
4 influence on the Environment
In recent years, due to the large amount of antibacterial drugs used in animal husbandry, antibiotics in particular have been increasingly used. After some antibiotics enter an animal body, the antibiotics are finally excreted to the external environment mainly through excrement in the form of prototypes or metabolites, so that environmental pollution is caused, and when the substances exceed the self-cleaning capacity of the environment, the antibiotics have influence on microorganisms in the ecological environment and increase the strain tolerance in the environment. Therefore, the number of drug-resistant salmonella in the environment can be increased by several times, so that people and other organisms are at risk of infection caused by drug-resistant bacteria, and the drug-resistant salmonella and other organisms in the environment pose a great threat to the human beings and other organisms living in the environment.
Disclosure of Invention
Aiming at the problems, the invention provides an acid preparation composition for improving the production performance of meat pigeons, a preparation method and application.
In order to achieve the aim, the invention adopts the technical proposal that,
an acid preparation composition for improving the production performance of meat pigeons is characterized by comprising the following components:
preferably, the coating wall material is ethyl cellulose and/or polyacrylic resin IV and hydrogenated palm oil and/or chitosan.
Preferably, the organic acid complex specifically comprises the following components:
preferably, the essential oil compound specifically comprises the following components:
preferably, the blood enriching composition specifically comprises the following components:
preferably, the binder comprises microcrystalline cellulose and/or corn starch and beta-cyclodextrin and/or maltodextrin.
A method for preparing an acid preparation composition for improving the production performance of meat pigeons is characterized by comprising the following steps:
(1) placing benzoic acid into a temperature-controlled fluidized bed for heating and fluidizing;
(2) atomizing and spraying lactic acid, butyric acid and formic acid into a solid-liquid mixer to be mixed and adsorbed with powdery silicon dioxide to form a mixture 1;
(3) uniformly mixing the mixture 1 prepared in the step (2) with the pretreated benzoic acid, citric acid and a binder in a solid-solid mixer to form a mixture 2;
(4) adding carvacrol, thymol, eucalyptus oil, cinnamaldehyde and myrrh essential oil into a Tween 80 emulsifier for emulsification and homogenization, atomizing and spraying into a solid-liquid mixer for mixing and adsorbing with powdery silicon dioxide to form a mixture 3;
(5) ferrous lactate, folic acid and vitamin B12And white carbon black are uniformly mixed in a solid-solid mixer to form a mixture 4;
(6) uniformly mixing the mixture 2, the mixture 3 and the mixture 4 with nojirimycin (mulberry leaf extract) and the balance of white carbon black in a solid-solid mixer to form a mixture 5;
(7) the mixture 5 is lifted by a bucket elevator to a tabletting granulator to be made into tablets, and then the tablets are crushed in a crusher to form crushed granules 1.
(8) And (3) lifting the crushed particles 1 to a three-stage sieving machine to obtain crushed materials 2 with the particle size of 20-80 meshes.
(9) Putting the weighed ethyl cellulose and/or polyacrylic resin IV, hydrogenated palm oil and/or chitosan into a hot melting tank, and completely melting or completely dissolving the polyacrylic resin by using alcohol to obtain a coating material for later use;
(10) putting the crushed particles 2 into a coating machine through a vacuum feeding machine; starting a first spray gun, a second spray gun and a third spray gun in the coating machine, atomizing and spraying the coating material in the step (9) into the coating machine, and carrying out fluidized coating for 15-60 min; after coating, discharging materials, feeding into an automatic sieving machine, and sieving to obtain the finished product with the particle size of 10-40 meshes.
The application of the acid preparation composition is applied to meat pigeon feed main materials, wherein the weight ratio of the meat pigeon feed main materials to the composition is 1000: 1 to 5.
Compared with the prior art, the invention has the advantages and positive effects that,
the pigeon feed additive has reasonable formula design, provides a comprehensive solution for intestinal health of the pigeons, has unique hematopoietic and blood-enriching nutrition, flourishes qi and blood of the pigeons, has strong nutrition and oxygen transportation capability of organisms, and can solve the problems of low nutrient digestion and absorption rate, reduced immunologic function and the like caused by insufficient blood when the pigeons grow rapidly; on the other hand, the unique nojirimycin (mulberry leaf extract) has strong broad-spectrum antiviral efficacy and has strong inhibitory effect on RNA and DNA viruses. After the meat pigeon uses the scheme of the invention, harmful bacteria such as escherichia coli and the like in the intestinal tract are obviously reduced, the intestinal tract flora is balanced, intestinal tract diseases are reduced, the intestinal tract has strong digestibility of nutrient substances, the nutrient substances for growth are obviously increased, and the growth performance of the meat pigeon is rapidly improved; meanwhile, after the scheme of the invention is used, the virus diseases of the pigeons caused by viruses such as pigeon pox virus, pigeon paramyxovirus I and the like are obviously reduced, the survival rate of the pigeons is greatly increased, and the economic benefit of a pigeon farm is improved.
Detailed Description
In order that the above objects, features and advantages of the present invention can be more clearly understood, the present invention will be further described with reference to the following examples. It should be noted that the embodiments and features of the embodiments of the present application may be combined with each other without conflict.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced in other ways than those specifically described herein, and thus the present invention is not limited to the specific embodiments of the present disclosure.
The invention provides an acid preparation composition for improving the production performance of meat pigeons, a preparation method and application thereof, and aims to achieve the effective regulation and control target of preventing and controlling enteritis by using a blood enriching and hemopoietic technology of compounding and matching an acid preparation and essential oil under the condition of not using antibiotic medicines, so that the nonreactive green safe and healthy breeding of the meat pigeons is realized. The acidifier composition can rapidly acidify gastrointestinal tract, rapidly reduce pH in stomach, improve activity of pepsin, enhance stomach barrier function, inhibit growth and reproduction of harmful flora in intestinal tract, regulate flora structure balance in intestinal tract, and repair damaged intestinal tract. The essential oil compound from natural plants has no toxic or side effect, and the growth and the propagation of pathogenic bacteria are inhibited by changing the cellular morphological structure of pathogenic bacteria, changing the morphological structure of mycelium to induce the dissolution of mycelium, reducing or inhibiting the generation and the germination of conidium or destroying the fertilization effect of the conidium; while the essential oil is purified by direct removal of H2O2Free radicals such as superoxide, hydroxyl ions and superoxide anions, lipid peroxidation reduction, reduction capacity increase, oxidation resistance enhancement, free radical accumulation reduction, oxidation resistance enhancement and immunity enhancement.
The acid preparation composition for improving the production performance of the meat pigeons is obviously superior to common daily ration in improving the production performance of the meat pigeons, and the benzoic acid and the formic acid have extremely strong bactericidal and bacteriostatic effects on escherichia coli, salmonella, mould and the like; the essential oil compound can help benzoic acid and formic acid to rapidly enter harmful bacteria cells by changing the permeability of harmful bacteria cell membranes, so that the antibacterial and bactericidal effects of the essential oil compound are enhanced, and the essential oil compound has a synergistic effect with organic acid; meanwhile, the nojirimycin (mulberry leaf extract) inhibits synthesis and modification of virus outer membrane glycoprotein by inhibiting the activity of alpha-glucosidase and mannose dehydrogenase, so that cell fusion, virus and host cell receptor combination, virus penetration and syncytium formation are inhibited to inhibit virus replication, and the nojirimycin is a broad-spectrum RNA and DNA virus inhibitor. After entering the stomach, the acid preparation composition can quickly reduce the pH value of the stomach, promote the pepsinogen to be converted into pepsin, and improve the activity of pepsin, so that the digestion of nutrients such as protein is improved. According to the invention, essential oil such as carvacrol reduces gene expression of related cytokines such as TNF-alpha and IL-6, so that the content of proinflammatory factors is reduced, and intestinal inflammation is reduced; on the other hand, the eucalyptus essential oil also has the functions of killing parasites in the meat pigeons, improving the intestinal health of the meat pigeons and improving the digestion and absorption functions of the intestinal tracts, thereby improving the production performance of the meat pigeons.
The invention has the following specific beneficial effects:
(1) bacteriostasis and sterilization: the benzoic acid and the formic acid in the acid preparation compound are extremely easy to enter harmful bacteria cells in a molecular form through a passive diffusion mode due to the lipophilic characteristic of molecules of the benzoic acid and the formic acid, a large number of hydrogen ions are rapidly dissociated from the benzoic acid and the formic acid molecules entering the bacteria cells due to potential difference, and the accumulation of the hydrogen ions causes the internal environment disorder of the bacteria cells, causes the metabolic activity disorder of the bacteria cells, and further causes the energy synthesis to be blocked; meanwhile, the accumulated hydrogen ions need to be pumped out by the bacterial cells, a large amount of energy needs to be consumed in the process, and the propagation and life activities of harmful bacteria are damaged due to energy consumption, so that the bacteriostatic and bactericidal effects are achieved; the lactic acid and the citric acid of the acid preparation compound are both smaller than benzoic acid and formic acid in PKa values, so that the lactic acid and the citric acid can preferentially release hydrogen ions in a microenvironment to ensure that the microenvironment is in a low pH environment so as to ensure that the benzoic acid and the formic acid are stored in more molecular forms, thereby improving the bacteriostatic and bactericidal effects of the compound; the essential oil compound of the invention helps benzoic acid and formic acid to rapidly enter harmful bacteria cells by changing the permeability of harmful bacteria cell membranes, thereby enhancing the antibacterial and bactericidal effects of the compounds.
(2) The antiviral effect is as follows: the nojirimycin (mulberry leaf extract) of the present invention is a piperidine alkaloid and is a broad spectrum RNA and DNA virus inhibitor. The alpha-glucosidase and mannose dehydrogenase activity inhibition effect inhibits synthesis and modification of virus outer membrane glycoprotein, so that cell fusion, virus and host cell receptor combination, virus penetration and syncytium formation are inhibited, replication of the virus is inhibited, and the virus is inhibited.
(3) Growth promoting effect: after entering the stomach, the acidifier compound can quickly release hydrogen ions to reduce the pH value in the stomach, and the low pH value in the stomach can promote pepsinogen to be converted into pepsin and improve the activity of the pepsin; meanwhile, the protein can be promoted to denature, the quaternary structure of the protein is opened and becomes a single chain, and the contact area of protease is increased, so that the digestibility of the daily ration protein is improved, and the digestion function of the protein is promoted; the carvacrol and the cinnamaldehyde in the essential oil compound accelerate the surface maturation of intestinal villi and the renewal rate of intestinal epithelial cells, promote the maturation of an endothelial layer of a digestive tract, stimulate the development of the intestinal villi, increase the digestion and absorption area and promote the secretion of various digestive enzymes in the intestinal tract, thereby improving the digestion and absorption functions of the meat pigeons and improving the digestion and utilization rate of feeds.
(4) Improving the immunity of the organism: the immunity refers to the defense mechanism of animals, is the physiological reaction for recognizing and eliminating the abnormal self, and is the capability of resisting invasion and maintaining the stability of the environment in the organism; from the new coronavirus pneumonia epidemic situation in 2020, people with strong immunity have fewer chances to suffer from the disease, and even if the people suffer from the disease, most of the people are mild diseases and can be quickly cured, while severe patients are mostly old people, so that the number of basic diseases is large, and the immunity is low; the invention adds ferrous lactate, folic acid and vitamin B12The active ingredients for hemopoiesis and blood enriching can quickly supplement raw materials required by hemopoiesis and blood enriching of organisms and promote the generation of bone marrow hemopoietic stem cells; the meat pigeon has strong hematopoietic capacity, abundant blood, more oxygen and nutrient substances, more nutrient substances for growth and immunity, faster growth and stronger immunity; meanwhile, the red blood cells are the largest immune cells of animal bodies, and the red blood cells are adhered to immune complexes through the proteins of complement receptors on the surfaces of the cells, so that the red blood cells are carried, transported and cleared of circulating immune complexes in vivoThe main contributor to compound (CIC).
(5) Reducing the occurrence of intestinal inflammation: the inflammation reaction is an important immune response, excessive inflammation reaction can damage the health of animals, cytokines are main factors for mediating the inflammation reaction, and comprise proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6) and the like and anti-inflammatory cytokines such as interleukin-10 (IL-10), wherein the proinflammatory cytokines are mainly secreted and produced by immune cells, and essential oil such as carvacrol and the like reduces the expression of genes of related cytokines such as TNF-alpha and IL-6, so that the content of the proinflammatory factors is reduced, and the inflammation reaction of the animals is relieved.
(6) Killing parasites: the eucalyptus essential oil is rich in a plurality of plant active ingredients such as eucalyptol, monoterpene, sesquiterpene and the like, has extremely strong penetrating power and permeability, and can destroy the cell membrane structure of the parasite through the fat solubility of the eucalyptus essential oil, so that the cell structure of the parasite is destroyed, and the parasite is inhibited or killed.
Example 1
The acid preparation composition for improving the production performance of the meat pigeons comprises 10% of coating wall material, 5% of binder, 0.5% of tween 80 emulsifier, 5% of silicon dioxide, 20% of organic acid compound, 5% of essential oil compound, 0.2% of nojirimycin (mulberry leaf extract), 1% of blood-enriching compound and the balance of white carbon black.
In the embodiment, the envelope wall material is ethyl cellulose and/or polyacrylic resin IV, hydrogenated palm oil and/or chitosan; the binder is microcrystalline cellulose and/or corn starch, beta-cyclodextrin and/or maltodextrin.
Further, the organic acid compound consists of 30% of benzoic acid, 10% of formic acid, 5% of butyric acid, 5% of lactic acid, 5% of citric acid and the balance of white carbon black.
Further, the essential oil compound consists of 10% of carvacrol, 10% of thymol, 10% of eucalyptus oil, 10% of cinnamaldehyde, 10% of myrrh essential oil and the balance of white carbon black.
Further, the blood-enriching compound comprises 40% of ferrous lactate, 5% of folic acid and vitamin B1210% and the balance white carbon black.
The production preparation method in the embodiment comprises the following steps:
(1) benzoic acid pretreatment, namely placing the benzoic acid into a temperature-controlled fluidized bed to be heated and fluidized;
(2) atomizing and spraying lactic acid, butyric acid and formic acid into a solid-liquid mixer to be mixed and adsorbed with powdery silicon dioxide to form a mixture 1;
(3) uniformly mixing the mixture 1 prepared in the step (2) with the pretreated benzoic acid, citric acid and a binder in a solid-solid mixer to form a mixture 2;
(4) adding carvacrol, thymol, eucalyptus oil, cinnamaldehyde and myrrh essential oil into a Tween 80 emulsifier for emulsification and homogenization, atomizing and spraying into a solid-liquid mixer for mixing and adsorbing with powdery silicon dioxide to form a mixture 3;
(5) ferrous lactate, folic acid and vitamin B12And white carbon black are uniformly mixed in a solid-solid mixer to form a mixture 4;
(6) uniformly mixing the mixture 2, the mixture 3 and the mixture 4 with nojirimycin (mulberry leaf extract) and the balance of white carbon black in a solid-solid mixer to form a mixture 5;
(7) the mixture 5 is lifted by a bucket elevator to a tabletting granulator to be made into tablets, and then the tablets are crushed in a crusher to form crushed granules 1.
(8) And (3) lifting the crushed particles 1 to a three-stage sieving machine to obtain crushed materials 2 with the particle size of 20-80 meshes.
(9) Putting the weighed ethyl cellulose and/or polyacrylic resin IV, hydrogenated palm oil and/or chitosan into a hot melting tank, and completely melting or completely dissolving the polyacrylic resin by using alcohol to obtain a coating material for later use;
(10) putting the crushed particles 2 into a coating machine through a vacuum feeding machine; starting a first spray gun, a second spray gun and a third spray gun in the coating machine, atomizing and spraying the coating material in the step (9) into the coating machine, and carrying out fluidized coating for 15-60 min; after coating, discharging materials, feeding into an automatic sieving machine, and sieving to obtain the finished product with the particle size of 10-40 meshes.
The application scheme of the embodiment is that the weight ratio of the meat pigeon feed main material to the composition is 1000: 1.
example 2
The acid preparation composition for improving the production performance of the meat pigeons comprises 20% of coating wall materials, 7.5% of binding agents, 0.75% of tween 80 emulsifiers, 7.5% of silicon dioxide, 30% of organic acid compounds, 6.5% of essential oil compounds, 0.6% of nojirimycin (mulberry leaf extract), 2% of blood enriching compounds and the balance of white carbon black.
In the embodiment, the envelope wall material is ethyl cellulose and/or polyacrylic resin IV, hydrogenated palm oil and/or chitosan; the binder is microcrystalline cellulose and/or corn starch, beta-cyclodextrin and/or maltodextrin.
Further, the organic acid compound consists of 37.5% of benzoic acid, 12.5% of formic acid, 6.5% of butyric acid, 6.5% of lactic acid, 6.5% of citric acid and the balance of white carbon black.
Further, the essential oil compound consists of 12.5% of carvacrol, 12.5% of thymol, 12.5% of eucalyptus oil, 12.5% of cinnamaldehyde, 12.5% of myrrh essential oil and the balance of white carbon black.
Further, the blood-enriching compound comprises 45% of ferrous lactate, 10% of folic acid and vitamin B1212.5% and the balance white carbon black.
The production preparation method in the embodiment comprises the following steps:
(1) benzoic acid pretreatment: placing benzoic acid into a temperature-controlled fluidized bed for heating and fluidizing;
(2) atomizing and spraying lactic acid, butyric acid and formic acid into a solid-liquid mixer to be mixed and adsorbed with powdery silicon dioxide to form a mixture 1;
(3) uniformly mixing the mixture 1 prepared in the step (2) with the pretreated benzoic acid, citric acid and a binder in a solid-solid mixer to form a mixture 2;
(4) adding carvacrol, thymol, eucalyptus oil, cinnamaldehyde and myrrh essential oil into a Tween 80 emulsifier for emulsification and homogenization, atomizing and spraying into a solid-liquid mixer for mixing and adsorbing with powdery silicon dioxide to form a mixture 3;
(5) ferrous lactate, folic acid and vitamin B12And white carbon black in a solid-solid mixerMixing uniformly to form a mixture 4;
(6) uniformly mixing the mixture 2, the mixture 3 and the mixture 4 with nojirimycin (mulberry leaf extract) and the balance of white carbon black in a solid-solid mixer to form a mixture 5;
(7) the mixture 5 is lifted by a bucket elevator to a tabletting granulator to be made into tablets, and then the tablets are crushed in a crusher to form crushed granules 1.
(8) And (3) lifting the crushed particles 1 to a three-stage sieving machine to obtain crushed materials 2 with the particle size of 20-80 meshes.
(9) Putting the weighed ethyl cellulose and/or polyacrylic resin IV, hydrogenated palm oil and/or chitosan into a hot melting tank, and completely melting or completely dissolving the polyacrylic resin by using alcohol to obtain a coating material for later use;
(10) putting the crushed particles 2 into a coating machine through a vacuum feeding machine; starting a first spray gun, a second spray gun and a third spray gun in the coating machine, atomizing and spraying the coating material in the step (9) into the coating machine, and carrying out fluidized coating for 15-60 min; after coating, discharging materials, feeding into an automatic sieving machine, and sieving to obtain the finished product with the particle size of 10-40 meshes.
The application scheme of the embodiment is that the weight ratio of the meat pigeon feed main material to the composition is 1000: 3.
example 3
The acid preparation composition for improving the production performance of the meat pigeons comprises 30% of coating wall materials, 10% of binders, 1% of tween 80 emulsifiers, 10% of silicon dioxide, 40% of organic acid compounds, 8% of essential oil compounds, 1% of nojirimycin (mulberry leaf extract), 3% of blood enriching compounds and the balance of white carbon black.
In the embodiment, the envelope wall material is ethyl cellulose and/or polyacrylic resin IV, hydrogenated palm oil and/or chitosan; the binder is microcrystalline cellulose and/or corn starch, beta-cyclodextrin and/or maltodextrin.
Further, the organic acid compound consists of 45% of benzoic acid, 15% of formic acid, 8% of butyric acid, 8% of lactic acid, 8% of citric acid and the balance of white carbon black.
Further, the essential oil compound consists of 15% of carvacrol, 15% of thymol carvacrol, 15% of eucalyptol carvacrol, 15% of cinnamaldehyde carvacrol, 15% of myrrh essential oil carvacrol and the balance of white carbon black.
Further, the blood-enriching compound comprises 50% of ferrous lactate, 15% of folic acid and vitamin B1215% and the balance white carbon black.
The production preparation method in the embodiment comprises the following steps:
(1) benzoic acid pretreatment: placing benzoic acid into a temperature-controlled fluidized bed for heating and fluidizing;
(2) atomizing and spraying lactic acid, butyric acid and formic acid into a solid-liquid mixer to be mixed and adsorbed with powdery silicon dioxide to form a mixture 1;
(3) uniformly mixing the mixture 1 prepared in the step (2) with the pretreated benzoic acid, citric acid and a binder in a solid-solid mixer to form a mixture 2;
(4) adding carvacrol, thymol, eucalyptus oil, cinnamaldehyde and myrrh essential oil into a Tween 80 emulsifier for emulsification and homogenization, atomizing and spraying into a solid-liquid mixer for mixing and adsorbing with powdery silicon dioxide to form a mixture 3;
(5) ferrous lactate, folic acid and vitamin B12And white carbon black are uniformly mixed in a solid-solid mixer to form a mixture 4;
(6) uniformly mixing the mixture 2, the mixture 3 and the mixture 4 with nojirimycin (mulberry leaf extract) and the balance of white carbon black in a solid-solid mixer to form a mixture 5;
(7) the mixture 5 is lifted by a bucket elevator to a tabletting granulator to be made into tablets, and then the tablets are crushed in a crusher to form crushed granules 1.
(8) And (3) lifting the crushed particles 1 to a three-stage sieving machine to obtain crushed materials 2 with the particle size of 20-80 meshes.
(9) Putting the weighed ethyl cellulose and/or polyacrylic resin IV, hydrogenated palm oil and/or chitosan into a hot melting tank, and completely melting or completely dissolving the polyacrylic resin by using alcohol to obtain a coating material for later use;
(10) putting the crushed particles 2 into a coating machine through a vacuum feeding machine; starting a first spray gun, a second spray gun and a third spray gun in the coating machine, atomizing and spraying the coating material in the step (9) into the coating machine, and carrying out fluidized coating for 15-60 min; after coating, discharging materials, feeding into an automatic sieving machine, and sieving to obtain the finished product with the particle size of 10-40 meshes.
The application scheme of the embodiment is that the weight ratio of the meat pigeon feed main material to the composition is 1000: 5.
the following is a verification of the effect of the acid preparation composition for improving the production performance of meat pigeons on the growth performance of meat pigeons (in the test, the effect of the acid preparation composition for improving the production performance of meat pigeons on the growth performance of young pigeons is studied by adding the acid preparation composition for improving the production performance of meat pigeons into feed grains of breeding pigeons).
The breeding pigeon breeding method comprises the following steps that 1, 200 young pigeons which are bred in 20 months and have good body conditions and are 1 day old are selected as test animals in a test of a professional cooperative society of Gandong Heyuan county, parent pigeons and young pigeons are randomly grouped into 4 groups, and each group comprises 25 parent pigeons and 50 young pigeons; each pair of breeding pigeons feeds 2 young pigeons, which are weighed and recorded before they are grouped.
The first group is a control group, and is fed with common parent pigeon feed.
The second group is a test group, the parent pigeon feed containing the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 1 of the invention is fed, the parent pigeon feed is obtained by mixing a parent pigeon feed main material and the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 1 of the invention, and the weight ratio of the parent pigeon feed main material to the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 1 of the invention is 1000: 1.
the third group is a test group, the parent pigeon feed containing the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 2 of the invention is fed, the parent pigeon feed is obtained by mixing a parent pigeon feed main material and the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 2 of the invention, and the weight ratio of the parent pigeon feed main material to the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 2 of the invention is 1000: 3.
the fourth group is a test group, the parent pigeon feed containing the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 3 of the invention is fed, the parent pigeon feed is obtained by mixing a parent pigeon feed main material and the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 3 of the invention, and the weight ratio of the parent pigeon feed main material to the acid preparation composition for improving the production performance of the meat pigeons in the embodiment 3 of the invention is 1000: 5.
time and place of experiment: year 2020, day 10 month 1 to day 10 month 28, location: guangdong Heyuan city Heping county culture and culture professional cooperative.
The test results are as follows:
TABLE 1 Effect of acid preparation composition for improving the Productivity of meat pigeon on the growth of young pigeon
As can be derived from the above table, it is,
(1) compared with a control group, the average daily gain of the acid preparation composition group for improving the production performance of the meat pigeons is improved by 5.13 percent (the average daily gain of the acid preparation composition group for improving the production performance of the meat pigeons is 15.95 g/day, and the average daily gain of the control group is 15.17 g/day);
(2) compared with a control group, the total protein content and the albumin content of the acid preparation composition group for improving the production performance of the meat pigeons are respectively improved by 14.01 percent and 19.92 percent (the total protein content and the albumin content of the acid preparation composition group for improving the production performance of the meat pigeons are respectively 20.91g/L and 13.06g/L, while the total protein content and the albumin content of the control group are respectively 18.34g/L and 10.89 g/L);
(3) compared with a control group, the contents of immunoglobulin IgA and IgG in an acid preparation composition group for improving the production performance of the meat pigeons are respectively improved by 17.32 percent and 7.48 percent (the contents of immunoglobulin IgA and IgG in the acid preparation composition group for improving the production performance of the meat pigeons are respectively 2.37g/L and 4.31g/L, and the contents of immunoglobulin IgA and IgG in the control group are respectively 2.02g/L and 4.01 g/L);
(4) compared with the control group, the hemoglobin content of the acid preparation composition group for improving the production performance of the meat pigeons is improved by 8.3 percent (the hemoglobin content of the acid preparation composition group for improving the production performance of the meat pigeons is 239.67g/L, and the hemoglobin content of the control group is 221.3 g/L).
Total protein and albumin in serum can reflect the digestive absorption degree of the animal to protein, maintain the colloid osmotic pressure of the organism, increase the content of the protein, correspondingly improve the immunity of the organism, enhance the nutritional level of the organism and improve the capability of the organism for resisting the external adverse environment influence. IgA has the functions of resisting bacteria, viruses and toxins, plays a very important role in local mucosal immunity of respiratory tracts, digestive tracts and the like of organisms, and particularly has the function of resisting infection for pathogenic microorganisms infected by certain mucous membranes; IgG has the functions of resisting bacteria and viruses, neutralizing viruses to lose toxicity, conditioning, coagulating and precipitating antigens, and playing an important role in humoral immunity. Hemoglobin is a protein responsible for oxygen transport (abbreviated as HB or HGB) that makes blood red in higher organisms; the red blood cells contain a large amount of hemoglobin (Hb), the function of the red blood cells is mainly completed by the hemoglobin, the hemoglobin can be used as a blood buffer substance to play a role, can be used as a transportation team of an organism to carry oxygen from the lung to tissues through arterial blood, and can carry carbon dioxide generated by the metabolism of the tissues to the lung through venous blood to be discharged out of the body; the degree of animal anemia can be better reflected through hemoglobin counting, and hemoglobin is often used as an important index for judging whether anemia exists clinically.
The test result shows that the acid preparation composition for improving the production performance of the meat pigeons can obviously improve the contents of total protein, albumin, IgA, IgG and hemoglobin of the young pigeons, and the acid preparation composition for improving the production performance of the meat pigeons can obviously improve the growth performance and the immune function of the young pigeons by adding the acid preparation composition for improving the production performance of the meat pigeons into the parent pigeon feed.
The acid preparation composition for improving the production performance of the meat pigeons is obviously superior to common daily ration in improving the production performance of the meat pigeons, and the benzoic acid and the formic acid have extremely strong bactericidal and bacteriostatic effects on escherichia coli, salmonella, mould and the like; the essential oil compound can help benzoic acid and formic acid to rapidly enter harmful bacteria cells by changing the permeability of harmful bacteria cell membranes, so that the antibacterial and bactericidal effects of the essential oil compound are enhanced, and the essential oil compound has a synergistic effect with organic acid; meanwhile, the nojirimycin (mulberry leaf extract) inhibits synthesis and modification of virus outer membrane glycoprotein by inhibiting the activity of alpha-glucosidase and mannose dehydrogenase, so that cell fusion, virus and host cell receptor combination, virus penetration and syncytium formation are inhibited to inhibit virus replication, and the nojirimycin is a broad-spectrum RNA and DNA virus inhibitor. After entering the stomach, the acid preparation composition can rapidly acidify the stomach, reduce the pH value of the stomach, promote the pepsinogen to be converted into pepsin, and improve the activity of the pepsin, thereby improving the digestion of protein and other nutrient substances; on the other hand, essential oils such as carvacrol and cinnamaldehyde have the effects of accelerating the surface maturation of intestinal villi and the renewal rate of intestinal epithelial cells, promoting the maturation of an endothelial layer of a digestive tract, stimulating the development of the intestinal villi, increasing the digestion and absorption area, and promoting the secretion of various digestive enzymes in the intestinal tract, so that the digestion and absorption functions of the meat pigeons are improved. According to the invention, essential oil such as carvacrol reduces gene expression of related cytokines such as TNF-alpha and IL-6, so that the content of proinflammatory factors is reduced, and intestinal inflammation is reduced; on the other hand, the eucalyptus essential oil also has the functions of killing parasites in the meat pigeons and improving the digestion and absorption of intestinal tracts, thereby improving the production performance of the meat pigeons.
The above description is only a preferred embodiment of the present invention, and not intended to limit the present invention in other forms, and any person skilled in the art may apply the above modifications or changes to the equivalent embodiments with equivalent changes, without departing from the technical spirit of the present invention, and any simple modification, equivalent change and change made to the above embodiments according to the technical spirit of the present invention still belong to the protection scope of the technical spirit of the present invention.
Claims (8)
2. the acid preparation composition for improving the production performance of meat pigeons according to claim 1, wherein the coating wall material is ethyl cellulose and/or polyacrylic resin IV and hydrogenated palm oil and/or chitosan.
6. the acid preparation composition for improving meat pigeon production performance of claim 1, wherein the binder comprises microcrystalline cellulose and/or corn starch and beta-cyclodextrin and/or maltodextrin.
7. A method for preparing the acid preparation composition for improving the production performance of meat pigeons, which is provided by any one of claims 2 to 6, is characterized by comprising the following steps:
(1) placing benzoic acid into a temperature-controlled fluidized bed for heating and fluidizing;
(2) atomizing and spraying lactic acid, butyric acid and formic acid into a solid-liquid mixer to be mixed and adsorbed with powdery silicon dioxide to form a mixture 1;
(3) uniformly mixing the mixture 1 prepared in the step (2) with the pretreated benzoic acid, citric acid and a binder in a solid-solid mixer to form a mixture 2;
(4) adding carvacrol, thymol, eucalyptus oil, cinnamaldehyde and myrrh essential oil into a Tween 80 emulsifier for emulsification and homogenization, atomizing and spraying into a solid-liquid mixer for mixing and adsorbing with powdery silicon dioxide to form a mixture 3;
(5) ferrous lactate, folic acid and vitamin B12And white carbon black are uniformly mixed in a solid-solid mixer to form a mixture 4;
(6) uniformly mixing the mixture 2, the mixture 3 and the mixture 4 with nojirimycin (mulberry leaf extract) and the balance of white carbon black in a solid-solid mixer to form a mixture 5;
(7) lifting the mixture 5 to a tabletting granulator by a bucket elevator to prepare a flaky object, and then crushing the flaky object in a crusher to form crushed particles 1;
(8) lifting the crushed particles 1 to a three-stage sieving machine to obtain crushed materials 2 with the particle size of 20-80 meshes;
(9) putting the weighed ethyl cellulose and/or polyacrylic resin IV, hydrogenated palm oil and/or chitosan into a hot melting tank, and completely melting or completely dissolving the polyacrylic resin by using alcohol to obtain a coating material for later use;
(10) putting the crushed particles 2 into a coating machine through a vacuum feeding machine; starting a first spray gun, a second spray gun and a third spray gun in the coating machine, atomizing and spraying the coating material in the step (9) into the coating machine, and carrying out fluidized coating for 15-60 min; after coating, discharging materials, feeding into an automatic sieving machine, and sieving to obtain the finished product with the particle size of 10-40 meshes.
8. The application of the acid preparation composition is characterized in that the acid preparation composition is applied to a meat pigeon feed main material, and the weight ratio of the meat pigeon feed main material to the composition is 1000: 1 to 5.
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