CN113039551A - 分析细胞的方法、细胞分析设备与计算机可读存储介质 - Google Patents
分析细胞的方法、细胞分析设备与计算机可读存储介质 Download PDFInfo
- Publication number
- CN113039551A CN113039551A CN201880099615.0A CN201880099615A CN113039551A CN 113039551 A CN113039551 A CN 113039551A CN 201880099615 A CN201880099615 A CN 201880099615A CN 113039551 A CN113039551 A CN 113039551A
- Authority
- CN
- China
- Prior art keywords
- cell
- cells
- probability
- information
- type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004458 analytical method Methods 0.000 title claims abstract description 114
- 238000000034 method Methods 0.000 title claims abstract description 92
- 210000004369 blood Anatomy 0.000 claims abstract description 38
- 239000008280 blood Substances 0.000 claims abstract description 38
- 238000012545 processing Methods 0.000 claims description 54
- 230000015654 memory Effects 0.000 claims description 33
- 230000003993 interaction Effects 0.000 claims description 19
- 230000008569 process Effects 0.000 claims description 18
- 230000001174 ascending effect Effects 0.000 claims description 16
- 238000003384 imaging method Methods 0.000 claims description 15
- 238000012216 screening Methods 0.000 claims description 8
- 230000004044 response Effects 0.000 claims description 7
- 238000013528 artificial neural network Methods 0.000 claims description 6
- 238000012163 sequencing technique Methods 0.000 claims description 6
- 230000003750 conditioning effect Effects 0.000 claims 2
- 210000004027 cell Anatomy 0.000 description 568
- 210000003979 eosinophil Anatomy 0.000 description 26
- 210000000440 neutrophil Anatomy 0.000 description 22
- 238000010586 diagram Methods 0.000 description 14
- 238000004590 computer program Methods 0.000 description 11
- 210000003651 basophil Anatomy 0.000 description 9
- 230000001360 synchronised effect Effects 0.000 description 7
- 238000001514 detection method Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 230000002159 abnormal effect Effects 0.000 description 5
- 238000012552 review Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 210000000601 blood cell Anatomy 0.000 description 3
- 230000014509 gene expression Effects 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- 238000003491 array Methods 0.000 description 2
- 238000011496 digital image analysis Methods 0.000 description 2
- 235000019800 disodium phosphate Nutrition 0.000 description 2
- 210000003714 granulocyte Anatomy 0.000 description 2
- 239000011229 interlayer Substances 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000003672 processing method Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000000592 Artificial Cell Substances 0.000 description 1
- 230000000735 allogeneic effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000002380 cytological effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011982 device technology Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000009347 mechanical transmission Effects 0.000 description 1
- 210000003593 megakaryocyte Anatomy 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 230000003448 neutrophilic effect Effects 0.000 description 1
- 210000003924 normoblast Anatomy 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
Landscapes
- Engineering & Computer Science (AREA)
- Theoretical Computer Science (AREA)
- Data Mining & Analysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Life Sciences & Earth Sciences (AREA)
- Evolutionary Biology (AREA)
- Evolutionary Computation (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Artificial Intelligence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
一种分析细胞的方法、设备和一种计算机可读存储介质，应用于细胞分析设备，所述方法包括：获取血液样本中细胞的数字图像(101)；对所获取的所述细胞的数字图像进行分类，以分别形成各个所述细胞的分类信息(102)；输出所述细胞的数字图像和所述细胞的分类信息(103)。
Description
PCT国内申请，说明书已公开。
Claims (38)
- PCT国内申请，权利要求书已公开。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311813052.6A CN117782948A (zh) | 2018-11-19 | 2018-11-19 | 分析细胞的方法、细胞分析设备与计算机可读存储介质 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2018/116275 WO2020102953A1 (zh) | 2018-11-19 | 2018-11-19 | 分析细胞的方法、细胞分析设备与计算机可读存储介质 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311813052.6A Division CN117782948A (zh) | 2018-11-19 | 2018-11-19 | 分析细胞的方法、细胞分析设备与计算机可读存储介质 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113039551A true CN113039551A (zh) | 2021-06-25 |
| CN113039551B CN113039551B (zh) | 2024-01-23 |
Family
ID=70773711
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311813052.6A Pending CN117782948A (zh) | 2018-11-19 | 2018-11-19 | 分析细胞的方法、细胞分析设备与计算机可读存储介质 |
| CN201880099615.0A Active CN113039551B (zh) | 2018-11-19 | 2018-11-19 | 分析细胞的方法、细胞分析设备与计算机可读存储介质 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311813052.6A Pending CN117782948A (zh) | 2018-11-19 | 2018-11-19 | 分析细胞的方法、细胞分析设备与计算机可读存储介质 |
Country Status (2)
| Country | Link |
|---|---|
| CN (2) | CN117782948A (zh) |
| WO (1) | WO2020102953A1 (zh) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1553166A (zh) * | 2003-12-19 | 2004-12-08 | 武汉大学 | 显微多光谱骨髓及外周血细胞自动分析仪和方法 |
| CN101490529A (zh) * | 2006-07-19 | 2009-07-22 | 海莫库公司 | 测量设备、方法和计算机程序 |
| CN103163287A (zh) * | 2011-12-09 | 2013-06-19 | 深圳迈瑞生物医疗电子股份有限公司 | 一种生物样本分析仪测量结果的处理方法及装置 |
| CN106294363A (zh) * | 2015-05-15 | 2017-01-04 | 厦门美柚信息科技有限公司 | 一种论坛帖子评价方法、装置及系统 |
| CN106462746A (zh) * | 2014-06-16 | 2017-02-22 | 西门子医疗保健诊断公司 | 分析数字全息显微术数据以用于血液学应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103020639A (zh) * | 2012-11-27 | 2013-04-03 | 河海大学 | 一种白细胞自动识别计数方法 |
| CN103679184A (zh) * | 2013-12-06 | 2014-03-26 | 河海大学 | 一种基于相关向量机的白细胞自动识别方法 |
| US9298968B1 (en) * | 2014-09-12 | 2016-03-29 | Flagship Biosciences, Inc. | Digital image analysis of inflammatory cells and mediators of inflammation |
| CN107729932B (zh) * | 2017-10-10 | 2019-07-26 | 杭州智微信息科技有限公司 | 骨髓细胞标记方法和系统 |
-
2018
- 2018-11-19 WO PCT/CN2018/116275 patent/WO2020102953A1/zh active Application Filing
- 2018-11-19 CN CN202311813052.6A patent/CN117782948A/zh active Pending
- 2018-11-19 CN CN201880099615.0A patent/CN113039551B/zh active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1553166A (zh) * | 2003-12-19 | 2004-12-08 | 武汉大学 | 显微多光谱骨髓及外周血细胞自动分析仪和方法 |
| CN101490529A (zh) * | 2006-07-19 | 2009-07-22 | 海莫库公司 | 测量设备、方法和计算机程序 |
| CN103163287A (zh) * | 2011-12-09 | 2013-06-19 | 深圳迈瑞生物医疗电子股份有限公司 | 一种生物样本分析仪测量结果的处理方法及装置 |
| CN106462746A (zh) * | 2014-06-16 | 2017-02-22 | 西门子医疗保健诊断公司 | 分析数字全息显微术数据以用于血液学应用 |
| CN106294363A (zh) * | 2015-05-15 | 2017-01-04 | 厦门美柚信息科技有限公司 | 一种论坛帖子评价方法、装置及系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113039551B (zh) | 2024-01-23 |
| CN117782948A (zh) | 2024-03-29 |
| WO2020102953A1 (zh) | 2020-05-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111325103B (zh) | 一种细胞标注系统和方法 | |
| AU2014237346B2 (en) | System and method for reviewing and analyzing cytological specimens | |
| US6148096A (en) | Specimen preview and inspection system | |
| US10573001B2 (en) | Quality control of automated whole-slide analyses | |
| US20090323062A1 (en) | Sample analyzer, particle distribution diagram displaying method and computer program product | |
| WO2018151680A1 (en) | Methods and devices for identifying population clusters in data | |
| JP2010078377A (ja) | 標本撮像装置 | |
| JPH11510282A (ja) | 分類のロバストネス測定装置および方法 | |
| CN114829933A (zh) | 一种样本分析系统及其自动精度管理方法 | |
| CN111684279B (zh) | 一种细胞分析方法、细胞分析装置及存储介质 | |
| CN113039551B (zh) | 分析细胞的方法、细胞分析设备与计算机可读存储介质 | |
| JP2010151523A (ja) | 粒子画像解析方法および装置 | |
| Moravapalle et al. | Blood count on a smartphone microscope: Challenges | |
| Nakamura et al. | Evaluation of two semi-supervised learning methods and their combination for automatic classification of bone marrow cells | |
| Merino et al. | Performance of the new MC‐80 automated digital cell morphology analyser in detection of normal and abnormal blood cells: Comparison with the CellaVision DM9600 | |
| JP3395627B2 (ja) | 生体の粒子画像の分類方法 | |
| GB2610426A (en) | System and method for identifying and counting biological species | |
| JP2000258335A (ja) | 尿沈渣自動分析装置及びデータ集中管理方式 | |
| CN115578316A (zh) | 样本图像分析设备、样本分析系统及样本图像分析方法 | |
| EP4261794A1 (en) | Image processing device, data management device, image processing system, image processing method, and non-transitory storage medium | |
| CN117952897A (zh) | 生物样本分析设备以及生物样本分析方法 | |
| CN112345778B (zh) | 级联的样本分析系统、装置和质控项目失控的处理方法 | |
| Monteiro et al. | Applied medical informatics in the detection and counting of erythrocytes and leukocytes through an image segmentation algorithm | |
| WO2021062741A1 (zh) | 一种信息处理方法、样本检测系统及计算机存储介质 | |
| CN112710821A (zh) | 细胞分析设备、分析细胞的方法、与计算机可读存储介质 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |