CN113038941A - 用于通过肺部施用治疗抑郁症的方法中的氯胺酮组合物 - Google Patents

用于通过肺部施用治疗抑郁症的方法中的氯胺酮组合物 Download PDF

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Publication number
CN113038941A
CN113038941A CN201980075601.XA CN201980075601A CN113038941A CN 113038941 A CN113038941 A CN 113038941A CN 201980075601 A CN201980075601 A CN 201980075601A CN 113038941 A CN113038941 A CN 113038941A
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CN
China
Prior art keywords
composition
ketamine
dose
administration
use according
Prior art date
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Pending
Application number
CN201980075601.XA
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English (en)
Chinese (zh)
Inventor
马切伊·维克佐雷克
瑟尔维亚·亚诺夫斯卡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novohar Therapeutics LLC
Original Assignee
Celon Pharma SA
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Publication date
Application filed by Celon Pharma SA filed Critical Celon Pharma SA
Publication of CN113038941A publication Critical patent/CN113038941A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201980075601.XA 2018-09-28 2019-09-24 用于通过肺部施用治疗抑郁症的方法中的氯胺酮组合物 Pending CN113038941A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18461615.9 2018-09-28
EP18461615.9A EP3628313B1 (en) 2018-09-28 2018-09-28 Ketamine composition for use in a method of treatment of depression by pulmonary administration
PCT/EP2019/075735 WO2020064748A1 (en) 2018-09-28 2019-09-24 Ketamine composition for use in a method of treatment of depression by pulmonary administration

Publications (1)

Publication Number Publication Date
CN113038941A true CN113038941A (zh) 2021-06-25

Family

ID=63713806

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980075601.XA Pending CN113038941A (zh) 2018-09-28 2019-09-24 用于通过肺部施用治疗抑郁症的方法中的氯胺酮组合物

Country Status (14)

Country Link
US (1) US11925607B2 (https=)
EP (3) EP3628313B1 (https=)
JP (1) JP7444864B2 (https=)
KR (1) KR102867739B1 (https=)
CN (1) CN113038941A (https=)
AU (1) AU2019349624B2 (https=)
BR (1) BR112021005687A2 (https=)
CA (1) CA3114325A1 (https=)
EA (1) EA202190724A1 (https=)
ES (2) ES3021221T3 (https=)
HU (2) HUE071303T2 (https=)
MX (1) MX2021003668A (https=)
PL (2) PL3628313T3 (https=)
WO (1) WO2020064748A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3505157T3 (pl) 2017-12-29 2022-04-11 Celon Pharma S.A. Kompozycja ketaminy w postaci suchego proszku do podawania dopłucnego w leczeniu depresji opornej na leczenie

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101466364A (zh) * 2006-03-22 2009-06-24 纽约大学西奈山医学院 鼻内施用氯胺酮治疗抑郁症
CN104519878A (zh) * 2012-03-12 2015-04-15 詹森药业有限公司 用于治疗顽固性或难治性抑郁症的艾氯胺酮
CN106562952A (zh) * 2015-10-09 2017-04-19 北京安珀科技有限责任公司 氯胺酮在治疗重性抑郁障碍中的应用
CN106714789A (zh) * 2014-08-13 2017-05-24 詹森药业有限公司 用于治疗抑郁症的方法
CN107735081A (zh) * 2015-05-20 2018-02-23 詹森药业有限公司 用于治疗抑郁症的方法和药盒
WO2019129397A1 (en) * 2017-12-29 2019-07-04 Celon Pharma S.A. Dry powder ketamine composition for use in the treatment of depression by pulmonary administration

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009469D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
GB0523031D0 (en) * 2005-11-11 2005-12-21 Yaupon Therapeutics Enhancement of morphine analgesia by s(-)-norketamine
DE102007009888A1 (de) 2007-02-28 2008-09-04 Hermann, Holger Lars, Dr. Verwendung von S-(+)-Ketamin zur Behandlung von Depressionen
GB0908129D0 (en) * 2009-05-12 2009-06-24 Innovata Ltd Composition
WO2014020155A1 (en) 2012-08-02 2014-02-06 Clinpharm Reform Gmbh Oral transmucosal adminstration forms of s-ketamine
PE20200404A1 (es) 2013-03-15 2020-02-26 Janssen Pharmaceutica Nv Composicion farmaceutica de clorhidrato de s-ketamina
CN116251084A (zh) 2013-03-15 2023-06-13 詹森药业有限公司 S-盐酸氯胺酮的药物组合物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101466364A (zh) * 2006-03-22 2009-06-24 纽约大学西奈山医学院 鼻内施用氯胺酮治疗抑郁症
CN104519878A (zh) * 2012-03-12 2015-04-15 詹森药业有限公司 用于治疗顽固性或难治性抑郁症的艾氯胺酮
CN106714789A (zh) * 2014-08-13 2017-05-24 詹森药业有限公司 用于治疗抑郁症的方法
CN107735081A (zh) * 2015-05-20 2018-02-23 詹森药业有限公司 用于治疗抑郁症的方法和药盒
CN106562952A (zh) * 2015-10-09 2017-04-19 北京安珀科技有限责任公司 氯胺酮在治疗重性抑郁障碍中的应用
WO2019129397A1 (en) * 2017-12-29 2019-07-04 Celon Pharma S.A. Dry powder ketamine composition for use in the treatment of depression by pulmonary administration

Also Published As

Publication number Publication date
PL3628313T3 (pl) 2025-06-23
JP2022502429A (ja) 2022-01-11
HUE071649T2 (hu) 2025-09-28
EP3628313A1 (en) 2020-04-01
EP3856159A1 (en) 2021-08-04
MX2021003668A (es) 2021-08-19
EP4578505A3 (en) 2025-09-03
US11925607B2 (en) 2024-03-12
EP3856159B1 (en) 2025-03-12
ES3021221T3 (en) 2025-05-26
EA202190724A1 (ru) 2021-08-18
KR20210068465A (ko) 2021-06-09
HUE071303T2 (hu) 2025-08-28
AU2019349624B2 (en) 2025-08-28
PL3856159T3 (pl) 2025-06-16
EP3856159C0 (en) 2025-03-12
US20210353560A1 (en) 2021-11-18
BR112021005687A2 (pt) 2021-06-22
ES3028459T3 (en) 2025-06-19
EP3628313B1 (en) 2025-02-12
CA3114325A1 (en) 2020-04-02
EP4578505A2 (en) 2025-07-02
EP3628313C0 (en) 2025-02-12
JP7444864B2 (ja) 2024-03-06
KR102867739B1 (ko) 2025-10-13
WO2020064748A1 (en) 2020-04-02
AU2019349624A1 (en) 2021-04-29

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Effective date of registration: 20251207

Address after: California, USA

Applicant after: Novohar Therapeutics LLC

Country or region after: U.S.A.

Address before: Polan Lomi Angi

Applicant before: CELON PHARMA S.A.

Country or region before: Poland