CN112999320A - Powder for preventing miscarriage and treating hypochondriac pain or preparation thereof - Google Patents

Powder for preventing miscarriage and treating hypochondriac pain or preparation thereof Download PDF

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Publication number
CN112999320A
CN112999320A CN202110214318.XA CN202110214318A CN112999320A CN 112999320 A CN112999320 A CN 112999320A CN 202110214318 A CN202110214318 A CN 202110214318A CN 112999320 A CN112999320 A CN 112999320A
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powder
preparation
parts
miscarriage
prevention
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徐静
林峰
王闯
杨宏富
王新嘉
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Jiangxi Zhengbang Breeding Co ltd
JIANGXI ZHENGBANG TECHNOLOGY CO LTD
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Jiangxi Zhengbang Breeding Co ltd
JIANGXI ZHENGBANG TECHNOLOGY CO LTD
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Publication of CN112999320A publication Critical patent/CN112999320A/en
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    • AHUMAN NECESSITIES
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
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Abstract

The invention discloses a powder for preventing miscarriage and treating swine or a preparation thereof, belonging to the technical field of powder preparations for preventing miscarriage and treating swine, wherein the preparation process of the powder preparation for preventing miscarriage and treating swine comprises the following specific steps: preparing a hypochondrium-free powder additive, preparing a microbial additive preparation and preparing a miscarriage-preventing hypochondrium-free powder, wherein the weight ratio of the hypochondrium-preventing hypochondrium-free powder additive to the hypochondrium-free powder additive is (7-8): 1, mixing to obtain the miscarriage prevention and hypochondriac prevention powder finished product, wherein the miscarriage prevention and hypochondriac prevention powder finished product and the microorganism additive preparation are mixed according to the weight ratio of 5: 1, the loranthus parasiticus powder preparation can prevent miscarriage, nourish liver and kidney, strengthen bones and muscles, prevent miscarriage, reduce the abortion rate of pregnant sows, improve the physique of the pregnant sows, influence the colonization of intestinal flora, increase the quantity of beneficial bacteria, reduce the quantity of pathogenic bacteria, further activate the local immunity and the whole body immunity of intestinal tracts, enhance the immunity and the anti-stress capability of the pregnant sows, reduce the feed amount, improve the utilization rate of the feed and reduce the production cost.

Description

Powder for preventing miscarriage and treating hypochondriac pain or preparation thereof
Technical Field
The invention relates to the technical field of powder preparations for preventing miscarriage and treating hypochondriac pain for pigs, in particular to powder for preventing miscarriage and treating hypochondriac pain or a preparation thereof.
Background
The livestock industry in China develops rapidly, the livestock and poultry stock keeping quantity and the annual output of livestock and poultry products increase year by year, the abortion of the sows becomes an important reason influencing the stable development of the pig industry in recent years, the average sow abortion rate is more than 23 percent, great economic loss is brought to the pig industry, according to the abortion time, it can be divided into recessive abortion, premature birth, dead birth, delayed abortion and habitual abortion, wherein the premature birth rate is high, which is mostly caused by nutrition deficiency, improper feeding management, indiscriminate use of antibiotic drugs and some self diseases, the prevention of sow abortion aims to strengthen the sanitary management of a pigsty and create a good environment for the growth and development of sows, the feed dosage is well mastered at each stage of the development and pregnancy of the sow, the feed safety system is strict, the feed which is mildewed and contains toxicity is firmly prevented from being used for feeding the sow, and the use of aphrodisiac medicines is subject to the principle of little use or no use; meanwhile, during pregnancy of the sow, the medicine can be used for preventing and treating, so that a miscarriage prevention preparation special for the pregnant sow is needed, according to the physiological characteristics of the pregnant sow, the formula is scientific, the preparation has obvious effects of preventing diseases, resisting diseases and replenishing blood, no side effect is caused, the immunity of the pregnant sow can be enhanced, the good health condition of the piglet in vivo can be maintained, a good foundation is laid for the healthy growth of the piglet after birth, and therefore the miscarriage prevention powder for the pig or the preparation thereof are provided.
Disclosure of Invention
The invention aims to provide a miscarriage-preventing and worry-free powder for pigs or a preparation thereof, so as to solve the problems mentioned in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: the powder for preventing miscarriage and treating hypochondriac pain of pigs or a preparation thereof comprises the following raw materials in parts by weight: 2-6 parts of composite probiotic agent, 60-100 parts of isomaltooligosaccharide, 180 parts of glucose 150-.
The processing technology of the miscarriage-preventing and hypochondrium-treating powder preparation comprises the following specific steps:
the method comprises the following steps: preparing a Wuxuan additive: selecting 10-25 parts of melastoma dodecandrum lour, 10-25 parts of eucommia bark, 10-18 parts of parasitic loranthus, 10-25 parts of semen cuscutae, 10-25 parts of white paeony root, 10-25 parts of dipsacus root and 10-25 parts of bighead atractylodes rhizome, sequentially cleaning, removing impurities and drying, and then sequentially frying the white paeony root and the bighead atractylodes rhizome, wherein the method specifically comprises the following steps:
(1) when the white atractylodes rhizome is fried to be brown, spraying clear water, taking out the white atractylodes rhizome by using a strainer and drying the white atractylodes rhizome;
(2) spraying the white paeony root with yellow wine uniformly, then frying until the white paeony root is slightly yellow, taking out the white paeony root and putting the white paeony root in a container for later use;
(3) the dried melastoma dodecandrum lour, eucommia bark, loranthus parasiticus, semen cuscutae, radix dipsaci, fried white paeony root and white atractylodes rhizome are decocted with water twice, the first decoction is carried out for 1-1.5 hours, then the suspension is kept stand and contained in a container for standby, the second decoction is carried out for 2-2.5 hours, then the suspension is kept stand and combined and contained in a first suspension container, the two decoctions are mixed and filtered, then the filtrate is concentrated to the relative density of 0.8-1.2, then water is added to 500ml, the mixing, the filtering and the sterilization treatment are carried out, and finally the solutions are subpackaged into bottles to complete the preparation of the melancholia-free powder additive;
step two: preparing a microorganism additive preparation: using three groups of comprehensive PDA slant culture media to respectively culture mucor for 5 days, bacillus subtilis for 1 day and lactobacillus acidophilus for 2 days, then respectively using 10.0mL sodium chloride injection and a bacteria inoculating hook to scrape and wash hypha of slant lawn for three times, then transferring the hypha into a triangular flask filled with 20.0mL sodium chloride injection, stirring the hypha for 30-40 minutes by a magnetic stirrer, thus preparing single cell suspension of three strains, putting the single cell suspension into 100.0mL PDA corn straw powder composite culture medium, respectively preparing seed liquids of the three strains for later use according to the mucor seed liquid: b, bacillus subtilis seed liquid: lactobacillus acidophilus seed liquid ═ 1: 2: 1, respectively measuring seed liquids of the three strains, mixing to prepare a microbial preparation, uniformly spraying the microbial preparation in a fermentation substrate, adding water to mix with the fermentation substrate according to the material-water ratio of 1:4, sealing the mixture for fermentation treatment, ensuring the fermentation temperature to be 30-35 ℃, and the fermentation time to be 6-9 days, wherein the obtained product is the microbial additive preparation;
step three: preparing miscarriage prevention and hypochondriac elimination powder: adding the composite probiotic agent (a mixture of enterococcus faecalis, saccharomycetes, bacillus subtilis and bacillus coagulans), isomaltose hypgather, glucose and citric acid in corresponding weight parts into a sterilized fermentation tank, uniformly mixing, adding distilled water to keep the humidity of a fermentation material at 60-80%, culturing for 36-72h at 30-35 ℃, and obtaining a primary bacterial liquid after finishing fermentation;
step four: centrifuging the preliminary bacterial liquid prepared in the step three in a centrifuge for 10-30min, taking the lower layer bacterial sludge in the centrifuge, and then drying and crushing to obtain a composite biological agent;
step five: taking corresponding parts by weight of astragalus mongholicus, honeysuckle, rhizoma atractylodis, alpinia katsumadai, semen cuscutae, parasitic loranthus and crispateleaf ardisia root, crushing the astragalus mongholicus, honeysuckle, rhizoma atractylodis, alpinia katsumadai, semen cuscutae, parasitic loranthus and crispateleaf ardisia root into particles of 200-fold sand and 500 meshes, uniformly mixing the particles with the composite biological preparation obtained in the fourth step, and sieving the particles with a 200-fold sand and;
step six: and (3) mixing the miscarriage prevention and hypochondrium prevention powder prepared in the fifth step and the hypochondrium prevention powder additive prepared in the first step according to the weight ratio of 7-8: 1, mixing to obtain the miscarriage prevention and hypochondriac prevention powder finished product, wherein the miscarriage prevention and hypochondriac prevention powder finished product and the microbial additive preparation prepared in the step two are mixed according to the weight ratio of 5: 1 mixing to prepare the miscarriage-preventing and hypochondriac-treating powder preparation.
Compared with the prior art, the invention has the beneficial effects that:
1. the miscarriage-preventing and hypochondriac-eliminating powder prepared by the invention contains the composite probiotic agent and the isomaltooligosaccharide, so that the activity of the preparation can be increased, the absorption capacity is increased, the isomaltooligosaccharide can not be absorbed by the stomach and small intestine, but directly enters the large intestine and is preferentially utilized by bifidobacterium, the mass propagation of the isomaltooligosaccharide is promoted, the isomaltooligosaccharide is a multiplication factor of the bifidobacterium, harmful bacteria in the intestinal tract can not be utilized, the growth of the harmful bacteria can be inhibited, the microecology in the intestinal tract can be adjusted to a benign cycle, the immune function of pregnant sows is enhanced, and the citric acid can also increase the feed intake and promote digestion;
2. in the miscarriage prevention and hypochondriac area powder prepared by the invention, the astragalus membranaceus can tonify qi, strengthen the exterior, enhance the immunity of pregnant sows, heal sores and promote granulation, reduce the occurrence of postpartum inflammation of the sows, eliminate phlegm and promote diuresis, the honeysuckle is used for clearing away heat and toxic materials, cool and disperse wind-heat, prevent wind-heat cold of the sows in the pregnancy period, the rhizoma atractylodis is used for eliminating dampness and strengthening spleen, the amomum tsao-ko is used for stimulating appetite and helping digestion, and the three can jointly promote the spleen and stomach of the pregnant; semen Cuscutae has effects of preventing miscarriage, nourishing liver and kidney, herba Taxilli has effects of strengthening tendons and bones, preventing miscarriage, reducing the miscarriage rate of pregnant sow, and improving body constitution of pregnant sow;
3. the microbial additive preparation prepared by the invention is composed of mucor, bacillus subtilis and lactobacillus acidophilus, the mucor can generate rich compound enzyme systems, so that wood fibers in raw materials are effectively degraded and converted, the lactobacillus acidophilus can further decompose cellulose macromolecules decomposed by the mucor, the particle size of the raw materials is reduced, the bulkiness of a fiber structure is further enhanced, the bacillus subtilis can generate a large amount of proteolytic enzyme, protein in a substrate is decomposed into micromolecular polypeptide as much as possible, the nutritive value of the feed is improved, the three are cultured together, and the small molecular polypeptide enter a sow body along with the feed in the form of viable bacteria, so that the colonization of intestinal flora can be influenced, the number of beneficial bacteria is increased, the number of pathogenic bacteria is reduced, and further the local immunity and the whole-body immunity of the intestinal tract are activated;
4. the melancholia powder additive prepared by the invention comprises the ingredients of Melastoma dodecandrum lour, eucommia ulmoides, parasitic loranthus, semen cuscutae, radix dipsaci, and fried white paeony root and bighead atractylodes rhizome, and the ingredients all belong to Chinese herbal medicine preparations, so that the melancholia powder additive has no toxic or side effect on pregnant sows, is safe to use, can enhance the immunity and the anti-stress capability of the pregnant sows, can reduce the feed feeding amount, improve the feed utilization rate, and reduce the production cost.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The miscarriage-preventing and hypochondrium-treating powder for the pigs or the preparation thereof is characterized in that: the medicinal powder preparation for treating hypochondriac pain is prepared from the following raw materials in parts by weight: 4 parts of composite probiotic agent, 70 parts of isomaltooligosaccharide, 150 parts of glucose, 150 parts of citric acid, 60 parts of astragalus membranaceus, 60 parts of honeysuckle, 40 parts of bighead atractylodes rhizome, 40 parts of rhizoma atractylodis, 50 parts of katsumade galangal seed, 40 parts of semen cuscutae, 50 parts of crispateleaf ardisia root, 15 parts of melastoma dodecandrum, 15 parts of eucommia bark, 30 parts of parasitic loranthus, 15 parts of white paeony root and 15 parts of dipsacus root. The processing technology of the miscarriage-preventing and hypochondrium-treating powder preparation comprises the following specific steps:
the method comprises the following steps: preparing a Wuxuan additive: selecting 10 parts of melastoma dodecandrum lour, 10 parts of eucommia bark, 15 parts of parasitic loranthus, 20 parts of semen cuscutae, 10 parts of white paeony root, 15 parts of dipsacus root and 20 parts of bighead atractylodes rhizome, cleaning, removing impurities and drying in the air, and then sequentially frying the white paeony root and the bighead atractylodes rhizome, wherein the method specifically comprises the following steps:
(1) when the white atractylodes rhizome is fried to be brown, spraying clear water, taking out the white atractylodes rhizome by using a strainer and drying the white atractylodes rhizome;
(2) spraying the white paeony root with yellow wine uniformly, then frying until the white paeony root is slightly yellow, taking out the white paeony root and putting the white paeony root in a container for later use;
(3) the dried melastoma dodecandrum lour, eucommia bark, loranthus parasiticus, semen cuscutae, radix dipsaci, fried white paeony root and white atractylodes rhizome are decocted with water twice, the first time of decoction is 1 hour, then the suspension is kept stand and contained in a container for standby, the second time of decoction is 2.5 hours, then the suspension is kept stand and combined and contained in a first suspension container, the two decoctions are mixed and filtered, then the filtrate is concentrated to the relative density of 0.9, water is added to 500ml, then the mixing, the filtering and the sterilization treatment are carried out, and finally the solutions are subpackaged into bottles to finish the preparation of the sanwu san additive;
step two: preparing a microorganism additive preparation: using three groups of comprehensive PDA slant culture media to respectively culture mucor for 5 days, bacillus subtilis for 1 day and lactobacillus acidophilus for 2 days, then respectively using 10.0mL sodium chloride injection and a bacteria inoculating hook to scrape and wash hypha of slant lawn for three times, then transferring the hypha into a triangular flask filled with 20.0mL sodium chloride injection, stirring the hypha for 30 minutes by a magnetic stirrer, preparing single cell suspension of three strains, putting the single cell suspension into 100.0mL PDA corn straw powder composite culture medium, respectively preparing seed solutions of the three strains for later use, and according to the mucor seed solution: b, bacillus subtilis seed liquid: lactobacillus acidophilus seed liquid ═ 1: 2: 1, respectively measuring seed liquids of the three strains, mixing the seed liquids to prepare a microbial preparation, uniformly spraying the microbial preparation in a fermentation substrate, adding water to mix the microbial preparation with the fermentation substrate according to the material-water ratio of 1:4, sealing the mixture for fermentation treatment, ensuring that the fermentation temperature is 35 ℃, and the fermentation time is 7 days, wherein the obtained product is the microbial additive;
step three: preparing miscarriage prevention and hypochondriac elimination powder: adding corresponding weight parts of composite probiotic (mixture of enterococcus faecalis, yeast, bacillus subtilis and bacillus coagulans), isomaltose hypgather, glucose and citric acid into a sterilized fermentation tank, uniformly mixing, adding distilled water to keep the humidity of the fermentation material at 60-80%, culturing for 48h at 35 ℃, and obtaining primary bacteria liquid after finishing fermentation;
step four: centrifuging the preliminary bacterial liquid prepared in the step three in a centrifuge for 25min, taking the lower layer bacterial sludge in the centrifuge, and then drying and crushing to obtain a composite biological agent;
step five: taking corresponding parts by weight of astragalus mongholicus, honeysuckle, rhizoma atractylodis, alpinia katsumadai, semen cuscutae, parasitic loranthus and crispateleaf ardisia root, crushing the astragalus mongholicus, honeysuckle, rhizoma atractylodis, alpinia katsumadai, semen cuscutae, parasitic loranthus and crispateleaf ardisia root into particles of 200-fold sand and 500 meshes, uniformly mixing the particles with the composite biological preparation obtained in the fourth step, and sieving the particles with a 200-fold sand and;
step six: and (3) mixing the miscarriage prevention and hypochondrium prevention powder prepared in the fifth step and the hypochondrium prevention powder additive prepared in the first step according to the weight ratio of 7: 1, mixing to obtain the miscarriage prevention and hypochondriac prevention powder finished product, wherein the miscarriage prevention and hypochondriac prevention powder finished product and the microbial additive preparation prepared in the step two are mixed according to the weight ratio of 5: 1 mixing to prepare the miscarriage-preventing and hypochondriac-treating powder preparation.
Example 2
The miscarriage-preventing and hypochondrium-treating powder for the pigs or the preparation thereof is characterized in that: the medicinal powder preparation for treating hypochondriac pain is prepared from the following raw materials in parts by weight: 6 parts of composite probiotic agent, 90 parts of isomaltooligosaccharide, 180 parts of glucose, 180 parts of citric acid, 80 parts of astragalus membranaceus, 80 parts of honeysuckle, 50 parts of bighead atractylodes rhizome, 50 parts of rhizoma atractylodis, 80 parts of katsumade galangal seed, 60 parts of semen cuscutae, 70 parts of crispateleaf ardisia root, 20 parts of melastoma dodecandrum, 20 parts of eucommia bark, 50 parts of parasitic loranthus, 25 parts of white paeony root and 25 parts of dipsacus root. The processing technology of the miscarriage-preventing and hypochondrium-treating powder preparation comprises the following specific steps:
the method comprises the following steps: preparing a Wuxuan additive: selecting 15 parts of melastoma dodecandrum lour, 15 parts of eucommia bark, 18 parts of parasitic loranthus, 25 parts of semen cuscutae, 20 parts of white paeony root, 20 parts of dipsacus root and 25 parts of bighead atractylodes rhizome, cleaning, removing impurities and drying in the air, and then sequentially frying the white paeony root and the bighead atractylodes rhizome, wherein the method specifically comprises the following steps:
(1) when the white atractylodes rhizome is fried to be brown, spraying clear water, taking out the white atractylodes rhizome by using a strainer and drying the white atractylodes rhizome;
(2) spraying the white paeony root with yellow wine uniformly, then frying until the white paeony root is slightly yellow, taking out the white paeony root and putting the white paeony root in a container for later use;
(3) the dried melastoma dodecandrum lour, eucommia bark, loranthus parasiticus, semen cuscutae, radix dipsaci, fried white paeony root and white atractylodes rhizome are decocted with water twice, the first decoction is carried out for 1.5 hours, then the suspension is kept stand and contained in a container for standby, the second decoction is carried out for 2 hours, then the suspension is kept stand and combined and contained in a first suspension container, the two decoctions are mixed and filtered, then the filtrate is concentrated to the relative density of 1.1, water is added to 500ml, the mixing, the filtering and the sterilization treatment are carried out, and finally the solutions are subpackaged into bottles to finish the preparation of the melanchree powder additive;
step two: preparing a microorganism additive preparation: using three groups of comprehensive PDA slant culture media to respectively culture mucor for 5 days, bacillus subtilis for 1 day and lactobacillus acidophilus for 2 days, then respectively using 10.0mL sodium chloride injection and a bacteria inoculating hook to scrape and wash hypha of slant lawn for three times, then transferring the hypha into a triangular flask filled with 20.0mL sodium chloride injection, stirring the hypha for 40 minutes by a magnetic stirrer, preparing single cell suspension of three strains, putting the single cell suspension into 100.0mL PDA corn straw powder composite culture medium, respectively preparing seed solutions of the three strains for later use, and according to the mucor seed solution: b, bacillus subtilis seed liquid: lactobacillus acidophilus seed liquid ═ 1: 2: 1, respectively measuring seed liquids of the three strains, mixing the seed liquids to prepare a microbial preparation, uniformly spraying the microbial preparation in a fermentation substrate, adding water to mix the microbial preparation with the fermentation substrate according to the material-water ratio of 1:4, sealing the mixture for fermentation treatment, ensuring the fermentation temperature to be 30 ℃, and ensuring the fermentation time to be 9 days, wherein the obtained product is the microbial additive preparation;
step three: preparing miscarriage prevention and hypochondriac elimination powder: adding corresponding weight parts of composite probiotic (mixture of enterococcus faecalis, yeast, bacillus subtilis and bacillus coagulans), isomaltose hypgather, glucose and citric acid into a sterilized fermentation tank, uniformly mixing, adding distilled water to keep the humidity of the fermentation material at 60-80%, culturing for 60h at 30 ℃, and obtaining primary bacteria liquid after finishing fermentation;
step four: centrifuging the preliminary bacterial liquid prepared in the step three in a centrifuge for 15min, taking the lower layer bacterial sludge in the centrifuge, and then drying and crushing to obtain a composite biological agent;
step five: taking corresponding parts by weight of astragalus mongholicus, honeysuckle, rhizoma atractylodis, alpinia katsumadai, semen cuscutae, parasitic loranthus and crispateleaf ardisia root, crushing the astragalus mongholicus, honeysuckle, rhizoma atractylodis, alpinia katsumadai, semen cuscutae, parasitic loranthus and crispateleaf ardisia root into particles of 200-fold sand and 500 meshes, uniformly mixing the particles with the composite biological preparation obtained in the fourth step, and sieving the particles with a 200-fold sand and;
step six: and (3) mixing the miscarriage prevention and hypochondrium prevention powder prepared in the fifth step and the hypochondrium prevention powder additive prepared in the first step according to the weight ratio of 8: 1, mixing to obtain the miscarriage prevention and hypochondriac prevention powder finished product, wherein the miscarriage prevention and hypochondriac prevention powder finished product and the microbial additive preparation prepared in the step two are mixed according to the weight ratio of 5: 1 mixing to prepare the miscarriage-preventing and hypochondriac-treating powder preparation.
The miscarriage-preventing and hypochondriac-eliminating powder prepared by the invention contains the composite probiotic agent and the isomaltooligosaccharide, can increase the activity of the preparation and the absorption capacity, the isomaltooligosaccharide can not be absorbed by stomach and small intestine, but directly enters large intestine and is preferentially utilized by bifidobacterium, the bifidobacterium can be promoted to breed in large quantity, the bifidobacterium can be promoted to obviously proliferate, the isomaltooligosaccharide can not be utilized by harmful bacteria in intestinal tract, the growth of the harmful bacteria can be inhibited, the microecology in the intestinal tract can be promoted to be adjusted to a benign cycle, the immune function of pregnant sows can be enhanced, the citric acid can also increase the feed intake and can promote digestion, the astragalus can tonify qi and strengthen the exterior of pregnant sows, the immunity of the pregnant sows can be enhanced, sore healing and granulation can be promoted, the occurrence of inflammation after the birth of the sows can be reduced, the ardisia crisps can eliminate phlegm, the rhizoma atractylodis eliminates dampness and strengthens spleen, the katsumadai seed promotes appetite and digestion, and the three can promote pregnant sows to strengthen spleen and stomach and prevent food retention and constipation; the dodder seed can prevent miscarriage, nourish liver and kidney, the loranthus parasiticus can strengthen bones and muscles, prevent miscarriage, reduce the abortion rate of pregnant sows and improve the physique of the pregnant sows, the microbial additive preparation consists of mucor, bacillus subtilis and lactobacillus acidophilus, the mucor can generate rich compound enzyme systems, so that the wood fiber in the raw material is effectively degraded and converted, the lactobacillus acidophilus can further decompose cellulose macromolecules decomposed by the mucor, the particle size of the raw material is reduced, the fluffy degree of a fiber structure is further enhanced, the bacillus subtilis can generate a large amount of proteolytic enzyme, protein in a substrate is decomposed into micromolecule polypeptide as much as possible, the nutritional value of the feed is improved, the three are cultured together, and the small molecular polypeptide enters the sows along with the feed in the form of live bacteria, can influence intestinal flora, increase the number of beneficial bacteria and reduce the number of pathogenic bacteria, so as to activate the local immunity and the whole body immunity of the intestinal tract, the melancholia-free powder additive comprises melastoma dodecandrum lour, eucommia ulmoides, parasitic loranthus, the dodder, the dipsacus root, the fried white paeony root and the fried white atractylodes rhizome, and the components belong to Chinese herbal medicine preparations, so that the melancholia-free powder additive has no toxic or side effect on pregnant sows, is safe to use, can enhance the immunity and the anti-stress capability of the pregnant sows, can reduce the feed feeding amount of feeds, improves the utilization rate of the feeds, and reduces the production cost.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (2)

1. The miscarriage-preventing and hypochondrium-treating powder for the pigs or the preparation thereof is characterized in that: the medicinal powder preparation for treating hypochondriac pain is prepared from the following raw materials in parts by weight: 2-6 parts of composite probiotic agent, 60-100 parts of isomaltooligosaccharide, 180 parts of glucose 150-.
2. The process for preparing the powder preparation for preventing miscarriage and treating hypochondriac pain according to claim 1, which comprises the following steps:
the method comprises the following steps: preparing a Wuxuan additive: selecting 10-25 parts of melastoma dodecandrum lour, 10-25 parts of eucommia bark, 10-18 parts of parasitic loranthus, 10-25 parts of semen cuscutae, 10-25 parts of white paeony root, 10-25 parts of dipsacus root and 10-25 parts of bighead atractylodes rhizome, sequentially cleaning, removing impurities and drying, and then sequentially frying the white paeony root and the bighead atractylodes rhizome, wherein the method specifically comprises the following steps:
(1) when the white atractylodes rhizome is fried to be brown, spraying clear water, taking out the white atractylodes rhizome by using a strainer and drying the white atractylodes rhizome;
(2) spraying the white paeony root with yellow wine uniformly, then frying until the white paeony root is slightly yellow, taking out the white paeony root and putting the white paeony root in a container for later use;
(3) the dried melastoma dodecandrum lour, eucommia bark, loranthus parasiticus, semen cuscutae, radix dipsaci, fried white paeony root and white atractylodes rhizome are decocted with water twice, the first decoction is carried out for 1-1.5 hours, then the suspension is kept stand and contained in a container for standby, the second decoction is carried out for 2-2.5 hours, then the suspension is kept stand and combined and contained in a first suspension container, the two decoctions are mixed and filtered, then the filtrate is concentrated to the relative density of 0.8-1.2, then water is added to 500ml, the mixing, the filtering and the sterilization treatment are carried out, and finally the solutions are subpackaged into bottles to complete the preparation of the melancholia-free powder additive;
step two: preparing a microorganism additive preparation: using three groups of comprehensive PDA slant culture media to respectively culture mucor for 5 days, bacillus subtilis for 1 day and lactobacillus acidophilus for 2 days, then respectively using 10.0mL sodium chloride injection and a bacteria inoculating hook to scrape and wash hypha of slant lawn for three times, then transferring the hypha into a triangular flask filled with 20.0mL sodium chloride injection, stirring the hypha for 30-40 minutes by a magnetic stirrer, thus preparing single cell suspension of three strains, putting the single cell suspension into 100.0mL PDA corn straw powder composite culture medium, respectively preparing seed liquids of the three strains for later use according to the mucor seed liquid: b, bacillus subtilis seed liquid: lactobacillus acidophilus seed liquid ═ 1: 2: 1, respectively measuring seed liquids of the three strains, mixing to prepare a microbial preparation, uniformly spraying the microbial preparation in a fermentation substrate, adding water to mix with the fermentation substrate according to the material-water ratio of 1:4, sealing the mixture for fermentation treatment, ensuring the fermentation temperature to be 30-35 ℃, and the fermentation time to be 6-9 days, wherein the obtained product is the microbial additive preparation;
step three: preparing miscarriage prevention and hypochondriac elimination powder: adding the composite probiotic agent (a mixture of enterococcus faecalis, saccharomycetes, bacillus subtilis and bacillus coagulans), isomaltose hypgather, glucose and citric acid in corresponding weight parts into a sterilized fermentation tank, uniformly mixing, adding distilled water to keep the humidity of a fermentation material at 60-80%, culturing for 36-72h at 30-35 ℃, and obtaining a primary bacterial liquid after finishing fermentation;
step four: centrifuging the preliminary bacterial liquid prepared in the step three in a centrifuge for 10-30min, taking the lower layer bacterial sludge in the centrifuge, and then drying and crushing to obtain a composite biological agent;
step five: taking corresponding parts by weight of astragalus mongholicus, honeysuckle, rhizoma atractylodis, alpinia katsumadai, semen cuscutae, parasitic loranthus and crispateleaf ardisia root, crushing the astragalus mongholicus, honeysuckle, rhizoma atractylodis, alpinia katsumadai, semen cuscutae, parasitic loranthus and crispateleaf ardisia root into particles of 200-fold sand and 500 meshes, uniformly mixing the particles with the composite biological preparation obtained in the fourth step, and sieving the particles with a 200-fold sand and;
step six: and (3) mixing the miscarriage prevention and hypochondrium prevention powder prepared in the fifth step and the hypochondrium prevention powder additive prepared in the first step according to the weight ratio of 7-8: 1, mixing to obtain the miscarriage prevention and hypochondriac prevention powder finished product, wherein the miscarriage prevention and hypochondriac prevention powder finished product and the microbial additive preparation prepared in the step two are mixed according to the weight ratio of 5: 1 mixing to prepare the miscarriage-preventing and hypochondriac-treating powder preparation.
CN202110214318.XA 2021-02-25 2021-02-25 Powder for preventing miscarriage and treating hypochondriac pain or preparation thereof Pending CN112999320A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113288918A (en) * 2021-06-23 2021-08-24 中南大学 Application of probiotics in preparation of medicine for treating injury of offspring caused by stress during pregnancy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113288918A (en) * 2021-06-23 2021-08-24 中南大学 Application of probiotics in preparation of medicine for treating injury of offspring caused by stress during pregnancy

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