CN112999284A - Lithospermum oil for treating infantile eczema and preparation method and using method thereof - Google Patents
Lithospermum oil for treating infantile eczema and preparation method and using method thereof Download PDFInfo
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Abstract
The invention discloses lithospermum oil for treating infantile eczema, belongs to the technical field of traditional Chinese medicine compositions, and particularly discloses the following raw materials in parts by weight: 4-8 parts of Sinkiang lithospermum, 8-12 parts of angelica sinensis, 8-12 parts of radix rehmanniae recen, 10-14 parts of radix angelicae, 8-12 parts of radix sileris, 3-7 parts of vinegar frankincense, 3-7 parts of vinegar myrrh and 8-12 parts of rheum officinale. Simultaneously discloses the following preparation method: 1) mixing the above materials, pulverizing, soaking in oleum Sesami, sealing, steaming for 45-70min, and filtering; 2) repeatedly adding sesame oil into the filter residue, sealing, steaming, filtering, and mixing the filtrates to obtain arnebia oil for treating infantile eczema. Has the effects of clearing away heat and toxic materials, removing necrotic tissue and promoting granulation, and has the advantages of simple preparation method, no wrinkle on skin of infant, good contact between medicine and affected part, and improved medicinal effect. And the preparation method is simple and convenient for industrial popularization.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, in particular to lithospermum oil for treating infant eczema and a preparation method and application thereof.
Background
Eczema is an allergic inflammatory skin disease caused by various internal and external factors. Clinical characteristics are that the skin lesions with multiple forms are symmetrically distributed, easy to exude, conscious pruritus, recurrent attacks and chronicity. Infantile eczema is called as infantile eczema or fetal wound healing in traditional Chinese medicine. The eczema can be divided into three types of acute, subacute and chronic diseases, the disease is equivalent to eczema of western medicine, infantile eczema generally appears in the period from 1 month to 2 years of age after birth, and the infantile eczema is most serious in 2-3 months. It is usually applied to cheek, scalp, forehead, eyebrow, neck, submaxillary region or behind ear, and can be extended to other regions. Modern medicine considers that eczema is caused by various simple or complex factors in the interior or the exterior, is an allergic skin disease, and is mainly caused by the fact that when allergen exists, namely, eczema can permeate through skin, and causes mental fatigue, tension and depression.
In the prior art, the main treatment of eczema is oral Chinese patent medicine, but the treatment period of the oral treatment mode is long, the oral treatment mode has no contact killing effect on bacteria, fungi and viruses on the sore surface and is easy to recur, and the external medicine mainly has the effects of sterilization and disinfection, and has single effect, low cure rate and easy recur. In addition, the immunity of the infants is low, the skin is delicate, components which are used with caution by the infants are often contained in the eczema cream in the prior art, and serious side effects can be brought when the eczema cream is used for the infants. Meanwhile, the common skin of the infants has more folds, and the affected parts in the folds are easy to miss only by applying the external ointment, so that the eczema cannot be radically cured.
Therefore, the problem to be solved by those skilled in the art is how to provide a Chinese medicinal composition for infants to effectively treat eczema.
Disclosure of Invention
In view of the above, the invention provides lithospermum oil for treating infant eczema and a preparation method and a using method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
the lithospermum oil for treating the infantile eczema comprises the following raw materials in parts by weight:
4-8 parts of Sinkiang lithospermum, 8-12 parts of angelica sinensis, 8-12 parts of radix rehmanniae recen, 10-14 parts of radix angelicae, 8-12 parts of radix sileris, 3-7 parts of vinegar frankincense, 3-7 parts of vinegar myrrh and 8-12 parts of rheum officinale.
Preferably, the feed comprises the following raw materials in parts by weight:
5-7 parts of Sinkiang lithospermum, 9-11 parts of angelica sinensis, 9-11 parts of radix rehmanniae recen, 11-13 parts of angelica dahurica, 9-11 parts of radix sileris, 4-6 parts of vinegar frankincense, 4-6 parts of vinegar myrrh and 9-11 parts of rhubarb.
Preferably, the feed comprises the following raw materials in parts by weight:
6 parts of Sinkiang lithospermum, 10 parts of angelica sinensis, 10 parts of radix rehmanniae recen, 12 parts of angelica dahurica, 10 parts of radix sileris, 5 parts of vinegar frankincense, 5 parts of vinegar myrrh and 10 parts of rhubarb.
Has the advantages that: sinkiang radix Arnebiae is root of Sinkiang radix Arnebiae of Boraginaceae. Collected in spring and autumn, and then dried in the sun or with slow fire. It is sweet, salty and cold in nature and taste. It enters heart and liver meridians. Has the functions of cooling blood, promoting blood circulation, detoxifying and promoting eruption. So it can be used for treating measles and macula without adequate eruption due to excessive blood heat and toxicity.
Angelica sinensis is dried root of Angelica sinensis (Oliv.) Diels of Umbelliferae, and has sweet and pungent taste and warm nature. It enters liver, heart and spleen meridians. Has effects in replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation. Can be used for treating blood deficiency and sallow complexion, giddiness and palpitation, menoxenia, amenorrhea and dysmenorrhea, asthenia cold and abdominal pain, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, intestinal dryness and constipation. The wine angelica sinensis can activate blood and promote menstruation. Can be used for treating amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.
The radix rehmanniae is fresh or dried root tuber of rehmannia glutinosa Libosch of Scrophulariaceae family, and is collected in autumn, and fresh after removing rhizoma Phragmitis, fibrous root and silt. Fresh rehmannia root, radix rehmanniae is sweet and bitter in taste and cold in nature, and enters heart, liver and kidney meridians. Has effects of clearing heat, promoting fluid production, cooling blood, and stopping bleeding. Can be used for treating yin impairment due to fever, crimson tongue with polydipsia, toxic heat and macula, hematemesis, epistaxis, and sore throat.
The radix Angelicae Dahuricae is a perennial herb with a height of 1-2.5 m, cylindrical root, a diameter of 2-5 cm at the base of the stem, one-time pinnate division of basal leaves, terminal or lateral growth of the umbrella-shaped inflorescence, and long-round to oval fruit. The main varieties include radix Angelicae Dahuricae, radix Angelicae Dahuricae (original variety), and radix Angelicae Pubescentis. The root is pungent in flavor and warm in nature. It enters lung, spleen and stomach meridians. Has effects in relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging nasal orifice, eliminating dampness, relieving leukorrhagia, relieving swelling, expelling pus, dispelling pathogenic wind, and relieving itching. Can be used for treating wind-cold type common cold, headache, toothache, rheumatalgia, nasosinusitis, leukorrhagia, skin sore, carbuncle, and toxic swelling.
Radix Saposhnikoviae is root of radix Saposhnikoviae belonging to family Umbelliferae, genus radix Saposhnikoviae, and it enters bladder, liver, spleen, and liver channels. Dispel wind and relieve exterior syndrome, subdue dampness and alleviate pain, stop spasm. Can be used for treating exterior syndrome due to exogenous pathogenic factor, rubella pruritus, rheumatalgia, tetanus, and spleen deficiency with excessive dampness.
The Olibanum is resin exuded from bark of Boswellia carterii Birdw of Burseraceae and Boswellia bhauradjiana Birdw of the same genus, and the vinegar Olibanum is obtained by parching clean Olibanum by vinegar roasting (the method of adding rice vinegar into the cleaned or cut medicine is called vinegar roasting method) until surface is bright. Vinegar-Boswellia carteri is pungent and bitter in flavor and warm in nature. It enters heart, liver and spleen meridians. Has effects in promoting blood circulation, activating qi-flowing, relieving pain, relieving swelling, and promoting granulation. Can be used for treating thoracic obstruction, cardialgia, epigastralgia, dysmenorrhea, amenorrhea, puerperal blood stasis, abdominal pain, rheumatalgia, spasm of muscles and tendons, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
The Myrrha is dried resin of Commiphora myrrha Engl or Commiphora molmol Engl of Canarium family, and vinegar Myrrha is prepared by parching neat Myrrha with vinegar until the surface is bright, and has pungent, bitter and mild properties. It enters heart, liver and spleen meridians. Dispel stasis, relieve pain, resolve swelling and promote tissue regeneration. Can be used for treating thoracic obstruction, cardialgia, gastralgia, dysmenorrhea, amenorrhea, puerperal blood stasis, abdominal mass, rheumatic arthralgia, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
The radix et rhizoma Rhei is rhizome of Rheum palmatum L., Rheum tanguticum Maxim. or Rheum officinale Baill. of Polygonaceae. Selecting plants growing for more than 3 years in 9-10 months, digging rootstocks, cutting off stems, leaves and rootstocks, scraping off rough skins and terminal buds, air-drying, drying or slicing and sun-drying. The main functional indications are as follows: purging heat-toxin, breaking stagnation and removing blood stasis. Treating excessive heat constipation, delirium, fever, food stagnation, abdominal fullness, dysentery, tenesmus, stasis, amenorrhea, abdominal mass, epidemic heat, acute conjunctivitis, hematemesis, epistaxis, yang jaundice, edema, stranguria with turbid urine, carbuncle, sore, and injury due to fire and dampness. Purge heat and unblock intestines, cool blood and remove toxicity, dispel stasis and dredge meridians. Can be used for treating constipation due to excessive heat, abdominal pain due to stagnation, dysentery, and jaundice due to damp-heat.
The lithospermum, the rheum officinale and the radix rehmanniae are matched with each other to generate a synergistic effect, so that the heat-clearing and detoxifying effects of the medicine are improved. In addition, the angelica dahurica, the vinegar-processed frankincense and the vinegar-processed myrrh all have the effect of detumescence, and the frankincense and the myrrh have the effect of promoting granulation, and the three are matched with each other to promote the generation of cells at an affected part, so that the healing of a wound is promoted. Meanwhile, the angelica sinensis can activate blood and dredge channels, and the divaricate saposhnikovia root can eliminate dampness and relieve exterior syndrome, and can eliminate dampness, relieve pain and stop spasm, so that skin stabbing pain and pruritus caused by eczema are relieved.
The raw materials in the invention are simple and easy to obtain, the production cost is greatly reduced, the burden of a patient is reduced, and meanwhile, the raw materials and the compatibility are safe and nontoxic, the allergenicity is low, and the infant can be directly used without causing irritation to skin.
A preparation method of lithospermum oil for treating infantile eczema comprises the following steps:
1) mixing the above materials, pulverizing, soaking in oleum Sesami, sealing, steaming for 45-70min, and filtering;
2) repeatedly adding sesame oil into the filter residue, sealing, steaming, filtering, and mixing the filtrates to obtain arnebia oil for treating infantile eczema.
Has the advantages that: the preparation method of the lithospermum oil provided by the invention is simple and easy to operate, and is convenient to prepare.
Preferably, the mesh number of the crushed raw materials in the step 1) is 40-80 meshes.
Has the advantages that: after the raw materials are crushed, the contact area between the raw materials and solvent sesame oil can be increased, and further, the leaching rate of effective substances in the raw materials is improved.
Preferably, the soaking time in the step 1) is 60-90 min.
Has the advantages that: the soaking time can ensure that the sesame oil is fully soaked in the raw materials, and further improves the leaching rate of effective substances in the raw materials.
Preferably, the solid-to-liquid ratio of the raw materials to the sesame oil in the step 1) is 1: 2-3.
Preferably, the solid-liquid mass ratio of the raw materials to the sesame oil in the step 2) is 1: 1-2.
Has the advantages that: the setting of the process parameters can ensure that effective substances in the raw materials can be fully extracted into the solvent water, the content of the effective substances in the product is improved, and the utilization rate of the raw materials is improved.
The use method of the lithospermum oil for treating the infant eczema is characterized by comprising the following steps: the lithospermum oil is directly smeared on the affected part, or is mixed with water according to the volume ratio of 1: 900-.
Has the advantages that: the invention is directly applied to the affected part of the skin of the infant, and can effectively promote the healing of the eczema. The lithospermum oil can be used in the infant bathing process, and further directly acts on any position of the skin, so that the affected part can be ensured to be directly contacted with the medicine, the medicine effect is improved, and meanwhile, the lithospermum oil can play a role in preventing eczema.
According to the technical scheme, compared with the prior art, the lithospermum oil for treating the infant eczema has the effects of clearing away heat and toxic materials, removing necrotic tissue and promoting granulation, is simple in preparation method, is mild, is suitable for being applied to infant skin, does not have adverse reaction, can effectively solve the problem of more wrinkles of the infant skin by using bath auxiliary treatment in the using process, ensures that the medicine is fully contacted with an affected part, and improves the effect of the medicine.
Detailed Description
The following will clearly and completely describe the technical solutions in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The lithospermum oil for treating the infantile eczema comprises the following raw materials in parts by weight:
6 parts of Sinkiang lithospermum, 10 parts of angelica sinensis, 10 parts of radix rehmanniae recen, 12 parts of angelica dahurica, 10 parts of radix sileris, 5 parts of vinegar frankincense, 5 parts of vinegar myrrh and 10 parts of rhubarb.
A preparation method of lithospermum oil for treating infantile eczema comprises the following steps:
mixing the raw materials, crushing to 40-80 meshes, adding the crushed raw materials into sesame oil, soaking for 60min, sealing, steaming in a steamer, ensuring that water vapor cannot enter the sesame oil in the steaming process, steaming for 60min, filtering, repeatedly adding the sesame oil into filter residues, sealing, steaming, filtering, and combining the filtrates to obtain the lithospermum oil for treating infantile eczema.
Example 2
The lithospermum oil for treating the infantile eczema comprises the following raw materials in parts by weight:
4 parts of Sinkiang lithospermum, 8 parts of angelica sinensis, 8 parts of radix rehmanniae recen, 10 parts of angelica dahurica, 8 parts of radix sileris, 3 parts of vinegar frankincense, 3 parts of vinegar myrrh and 8 parts of rhubarb.
A preparation method of lithospermum oil for treating infantile eczema comprises the following steps:
mixing the raw materials, crushing to 40-80 meshes, adding the crushed raw materials into sesame oil, soaking for 60min, sealing, steaming in a steamer, ensuring that water vapor cannot enter the sesame oil in the steaming process, steaming for 60min, filtering, repeatedly adding the sesame oil into filter residues, sealing, steaming, filtering, and combining the filtrates to obtain the lithospermum oil for treating infantile eczema.
Example 3
The lithospermum oil for treating the infantile eczema comprises the following raw materials in parts by weight:
8 parts of Sinkiang lithospermum, 12 parts of angelica sinensis, 12 parts of radix rehmanniae recen, 14 parts of angelica dahurica, 12 parts of radix sileris, 7 parts of vinegar frankincense, 7 parts of vinegar myrrh and 12 parts of rhubarb.
A preparation method of lithospermum oil for treating infantile eczema comprises the following steps:
mixing the raw materials, crushing to 40-80 meshes, adding the crushed raw materials into sesame oil, soaking for 60min, sealing, steaming in a steamer, ensuring that water vapor cannot enter the sesame oil in the steaming process, steaming for 60min, filtering, repeatedly adding the sesame oil into filter residues, sealing, steaming, filtering, and combining the filtrates to obtain the lithospermum oil for treating infantile eczema.
Example 4
The lithospermum oil for treating the infantile eczema comprises the following raw materials in parts by weight:
5 parts of Sinkiang lithospermum, 9 parts of angelica sinensis, 9 parts of radix rehmanniae recen, 11 parts of angelica dahurica, 9 parts of radix sileris, 4 parts of vinegar frankincense, 4 parts of vinegar myrrh and 9 parts of rhubarb.
A preparation method of lithospermum oil for treating infantile eczema comprises the following steps:
mixing the raw materials, crushing to 40-80 meshes, adding the crushed raw materials into sesame oil, soaking for 60min, sealing, steaming in a steamer, ensuring that water vapor cannot enter the sesame oil in the steaming process, steaming for 60min, filtering, repeatedly adding the sesame oil into filter residues, sealing, steaming, filtering, and combining the filtrates to obtain the lithospermum oil for treating infantile eczema.
Example 5
The lithospermum oil for treating the infantile eczema comprises the following raw materials in parts by weight:
7 parts of Sinkiang lithospermum, 11 parts of angelica sinensis, 11 parts of radix rehmanniae recen, 13 parts of angelica dahurica, 11 parts of radix sileris, 6 parts of vinegar frankincense, 6 parts of vinegar myrrh and 11 parts of rhubarb.
A preparation method of lithospermum oil for treating infantile eczema comprises the following steps:
mixing the raw materials, crushing to 40-80 meshes, adding the crushed raw materials into sesame oil, soaking for 60min, sealing, steaming in a steamer, ensuring that water vapor cannot enter the sesame oil in the steaming process, steaming for 60min, filtering, repeatedly adding the sesame oil into filter residues, sealing, steaming, filtering, and combining the filtrates to obtain the lithospermum oil for treating infantile eczema.
Application example 1
Infants were born in their own age of 1 year old, with exudative eczema, and involved the entire head and face. Initially on both cheeks, erythema occurs, no surface is present, and there are dense pinpoint blisters, papules and fluid exudation on the erythema. After the liniment is applied for 2 times/day, the exudation of exudates on the skin erosion surface is reduced, the erythema of the herpes dunghill is gradually light after two days, the herpes dunghill is continuously applied, and the eczema is cured after two weeks. During the medication process, patients do not have the symptoms of exacerbation or other anaphylactic reactions.
Application example 2
The infant slowly takes a certain time, the female is 2 years old, the back of the head of the infant suffers from dry eczema for three months, the initial rash is light red or dark red patch, the small dense papule has no blister, and the skin is dry and has no obvious exudation.
The medicine is applied for 2 times a day, and simultaneously the medicine is mixed with warm water according to the proportion of 1: 900-.
Application example 3
When a baby has a certain Liu, the baby is female in 8 months and suffers from seborrheic eczema for about 40 days, relating to scalp and face. Initially on the scalp, erythema and scaling appear in local areas. After the ointment is applied for 2 times/one day, the exudation of exudates from the skin erosion surface is reduced, after 2 days, the hypertrophic and chapped eczema skin with bran-shaped scales is gradually softened, the rash does not appear any more, the ointment is continuously applied, the affected part is slowly restored to the normal skin state, and after 10 days, the eczema is cured.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (9)
1. The lithospermum oil for treating infantile eczema is characterized by comprising the following raw materials in parts by weight: 4-8 parts of Sinkiang lithospermum, 8-12 parts of angelica sinensis, 8-12 parts of radix rehmanniae recen, 10-14 parts of radix angelicae, 8-12 parts of radix sileris, 3-7 parts of vinegar frankincense, 3-7 parts of vinegar myrrh and 8-12 parts of rheum officinale.
2. The lithospermum oil for treating infant eczema as claimed in claim 1, is characterized by comprising the following raw materials in parts by weight:
5-7 parts of Sinkiang lithospermum, 9-11 parts of angelica sinensis, 9-11 parts of radix rehmanniae recen, 11-13 parts of angelica dahurica, 9-11 parts of radix sileris, 4-6 parts of vinegar frankincense, 4-6 parts of vinegar myrrh and 9-11 parts of rhubarb.
3. The lithospermum oil for treating infant eczema as claimed in claim 2, is characterized by comprising the following raw materials in parts by weight:
6 parts of Sinkiang lithospermum, 10 parts of angelica sinensis, 10 parts of radix rehmanniae recen, 12 parts of angelica dahurica, 10 parts of radix sileris, 5 parts of vinegar frankincense, 5 parts of vinegar myrrh and 10 parts of rhubarb.
4. The preparation method of the lithospermum oil for treating the infant eczema as claimed in any one of claims 1 to 3, which is characterized by comprising the following steps of:
1) mixing the above materials, pulverizing, soaking in oleum Sesami, sealing, steaming for 45-70min, and filtering;
2) repeatedly adding sesame oil into the filter residue, sealing, steaming, filtering, and mixing the filtrates to obtain arnebia oil for treating infantile eczema.
5. The preparation method of lithospermum oil for treating infant eczema as claimed in claim 4, wherein the mesh number of the crushed raw materials in the step 1) is 40-80 meshes.
6. The preparation method of lithospermum oil for treating infant eczema as claimed in claim 5, wherein the soaking time in the step 1) is 60-90 min.
7. The preparation method of lithospermum oil for treating infantile eczema as claimed in claim 6, wherein the solid-to-liquid ratio of the raw materials to the sesame oil in step 1) is 1: 2-3.
8. The preparation method of lithospermum oil for treating infantile eczema as claimed in claim 4, wherein the solid-liquid mass ratio of the raw materials to the sesame oil in step 2) is 1: 1-2.
9. The use of arnebia oil for treating infant eczema as claimed in any of claims 1 to 3, comprising the steps of: the lithospermum oil is directly smeared on the affected part, or is mixed with water according to the volume ratio of 1: 900-.
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CN115569093A (en) * | 2022-09-09 | 2023-01-06 | 安徽亿人安股份有限公司 | A skin care cream with antibacterial effect for infant with dampness eliminating effect, and its preparation method |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN115569093A (en) * | 2022-09-09 | 2023-01-06 | 安徽亿人安股份有限公司 | A skin care cream with antibacterial effect for infant with dampness eliminating effect, and its preparation method |
CN115569093B (en) * | 2022-09-09 | 2023-10-13 | 安徽亿人安股份有限公司 | Infant dampness-dispelling skin-care cream with antibacterial effect and preparation method thereof |
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