CN112933184A - Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases and preparation method thereof - Google Patents

Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases and preparation method thereof Download PDF

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Publication number
CN112933184A
CN112933184A CN202110223108.7A CN202110223108A CN112933184A CN 112933184 A CN112933184 A CN 112933184A CN 202110223108 A CN202110223108 A CN 202110223108A CN 112933184 A CN112933184 A CN 112933184A
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parts
cerebrovascular diseases
preparation
root
treating cardiovascular
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何友明
刘大宏
彭景春
廖学刚
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Hunan Lanting Technology Development Co ltd
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Hunan Lanting Technology Development Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. The invention comprises the following components in parts by weight: 8-12 parts of pilose antler, 15-25 parts of prepared rehmannia root, 10-20 parts of platycladi seed, 10-20 parts of Chinese magnoliavine fruit, 10-20 parts of Chinese angelica, 10-20 parts of ligusticum wallichii, 10-20 parts of figwort root, 10-20 parts of frankincense, 10-20 parts of honeysuckle flower, 10-20 parts of pseudo-ginseng, 10-20 parts of white paeony root, 10-20 parts of salvia miltiorrhiza, 10-20 parts of dendrobium, 10-20 parts of cape jasmine fruit and 10-20 parts of liquorice. The invention combines the theories of traditional Chinese medicine such as the theory of yin and yang, the theory of channels and collaterals and the like, has scientific and reasonable compatibility, obvious curative effect on cardiovascular and cerebrovascular diseases, no side effect, convenient taking and economy.

Description

Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and a preparation method thereof.
Background
Cardiovascular and cerebrovascular diseases are the general names for cardiovascular and cerebrovascular diseases. At present, cardiovascular and cerebrovascular diseases are diseases with high morbidity, high disability rate, high death rate, high recurrence rate, high medical expense and many complications in China. Cardiovascular and cerebrovascular diseases mainly refer to 11 diseases such as coronary heart disease, myocardial infarction, cerebral thrombosis, hypertension, etc., and are caused by hypertension, hyperlipemia, hyperglycemia, blood hyperviscosity, platelet function enhancement, arteriosclerosis, in vivo free radical content increase and microcirculation disturbance; the more blood fat is accumulated on the vessel wall, atherosclerosis is caused, the vessel lumen is narrow and small, the blood flow is blocked, substances such as nutrient components, oxygen and the like cannot be smoothly conveyed to the required part of a body, wastes such as carbon dioxide and the like cannot be sufficiently taken away, and the vessel wall is thinned, embrittled and loses elasticity.
In the conventional treatment method at present, the operation has higher risk and is easy to have complications; the commonly used medicines have great side effects, and many patients need to take the medicines for life, which brings great harm to the viscera organs such as intestines, stomachs, livers and kidneys, and the like, causes the functional decline of the body, and further causes a series of pathological changes. Therefore, a medicament which has obvious curative effect and small toxic and side effect and is suitable for long-term use is urgently needed in the market.
Disclosure of Invention
Aiming at the technical problems, the invention aims to provide the traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and the preparation method thereof, and the traditional Chinese medicine preparation has the advantages of obvious curative effect on the cardiovascular and cerebrovascular diseases, no side effect, convenient taking, economy and practicability.
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight: 8-12 parts of pilose antler, 15-25 parts of prepared rehmannia root, 10-20 parts of platycladi seed, 10-20 parts of Chinese magnoliavine fruit, 10-20 parts of Chinese angelica, 10-20 parts of ligusticum wallichii, 10-20 parts of figwort root, 10-20 parts of frankincense, 10-20 parts of honeysuckle flower, 10-20 parts of pseudo-ginseng, 10-20 parts of white paeony root, 10-20 parts of salvia miltiorrhiza, 10-20 parts of dendrobium, 10-20 parts of cape jasmine fruit and 10-20 parts of liquorice.
Further, the traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by mass: 8-10 parts of pilose antler, 18-22 parts of prepared rehmannia root, 12-18 parts of platycladi seed, 12-18 parts of Chinese magnoliavine fruit, 12-18 parts of Chinese angelica, 12-18 parts of ligusticum wallichii, 12-18 parts of figwort root, 12-18 parts of frankincense, 12-18 parts of honeysuckle flower, 12-18 parts of pseudo-ginseng, 12-18 parts of white paeony root, 12-18 parts of salvia miltiorrhiza, 12-18 parts of dendrobium, 12-18 parts of cape jasmine fruit and 12-18 parts of liquorice.
Preferably, the traditional Chinese medicine medicament for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by mass: 10 parts of pilose antler, 20 parts of prepared rehmannia root, 15 parts of platycladi seed, 15 parts of Chinese magnoliavine fruit, 15 parts of Chinese angelica, 15 parts of ligusticum wallichii, 15 parts of figwort root, 15 parts of frankincense, 15 parts of honeysuckle, 15 parts of pseudo-ginseng, 15 parts of white paeony root, 15 parts of salvia miltiorrhiza, 15 parts of dendrobium, 15 parts of cape jasmine fruit and 15 parts of liquorice.
The preparation method of the traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases comprises the following steps:
(1) weighing the medicines according to the weight part ratio, and respectively drying the medicines;
(2) mixing and crushing the dried medicines, and sieving;
(3) adding honey into the medicinal powder, mixing, making into honeyed pill, and sealing for storage to obtain the Chinese medicinal preparation.
Further, the powder is sieved by a 120-mesh sieve with 100 meshes after being crushed in the step (2).
Further, the amount of the honey in the step (3) is 30-40% of the total mass of the medicine powder.
Compared with the prior art, the invention has the following beneficial effects:
the traditional Chinese medicine composition combines the theories of yin and yang, the theory of channels and collaterals and the like, has scientific and reasonable compatibility, has the effects of tonifying kidney and yang, tonifying kidney and nourishing essence, nourishing blood and yin, nourishing heart and soothing nerves, protecting liver and lowering enzyme, reinforcing kidney and tonifying qi, enriching blood and moistening dryness, activating blood and dissolving stasis, detoxifying and removing stasis, warming and activating vital energy and dissipating blood, dredging arthralgia and relieving pain, dissolving stasis and promoting tissue regeneration, regulating menstruation and regulating meridians, clearing heat and purging pathogenic fire, cooling blood and detoxifying and the like, has obvious treatment effect on cardiovascular and cerebrovascular diseases, has no side effect, is convenient to.
The invention relates to a traditional Chinese medicine preparation for treating insomnia, which has the following pharmacological effects by applying traditional Chinese medicines:
pilose antler: to tonify kidney, strengthen yang, tonify kidney and nourish essence.
Prepared rehmannia root: nourishing yin, nourishing essence and marrow, sweet in flavor, warm in nature, entering heart, liver and kidney meridians.
Arborvitae seed: nourish blood and tranquilize mind, nourish yin to relieve constipation, moisten intestines to relieve constipation.
Schisandra chinensis: invigorating spleen, replenishing qi, protecting liver, lowering transaminase, reinforcing kidney, and invigorating qi.
Chinese angelica: tonify blood, moisten dryness, regulate menstruation and alleviate pain.
Ligusticum wallichii: promoting blood circulation, removing blood stasis, dredging collaterals, and relieving pain.
Figwort root: clear heat, nourish yin, remove toxicity and dissipate nodulation.
Frankincense: pungent and warm herbs dispel heat, warm meridians and activate blood, move qi and relieve chest stuffiness, unblock arthralgia and alleviate pain.
Honeysuckle flower: clear heat and remove toxicity, cool blood and relieve swelling.
Pseudo-ginseng: clearing away heat, lowering blood pressure, relieving swelling, relieving pain, removing blood stasis, and stopping bleeding.
White peony root: nourish blood and regulate blood, soften liver and alleviate pain.
Red sage root: promoting blood circulation, removing blood stasis, dredging collaterals, relieving pain, regulating menstruation, and regulating pulse.
Dendrobe: nourish yin and nourish stomach, clear heat and promote fluid production.
Gardenia: clear heat and purge fire, cool blood and remove toxicity.
Licorice root: harmonize the drugs.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The materials used in the following examples are all commercially available from conventional sources.
Example 1
A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight: 8 parts of pilose antler, 25 parts of prepared rehmannia root, 10 parts of platycladi seed, 20 parts of Chinese magnoliavine fruit, 10 parts of Chinese angelica, 10 parts of ligusticum wallichii, 20 parts of figwort root, 20 parts of frankincense, 10 parts of honeysuckle flower, 20 parts of pseudo-ginseng, 10 parts of white paeony root, 10 parts of salvia miltiorrhiza, 20 parts of dendrobium, 20 parts of cape jasmine fruit and 10 parts of liquorice.
Example 2
A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight: 12 parts of pilose antler, 15 parts of prepared rehmannia root, 20 parts of platycladi seed, 10 parts of Chinese magnoliavine fruit, 20 parts of Chinese angelica, 20 parts of ligusticum wallichii, 10 parts of figwort root, 10 parts of frankincense, 20 parts of honeysuckle flower, 10 parts of pseudo-ginseng, 20 parts of white paeony root, 20 parts of salvia miltiorrhiza, 10 parts of dendrobium, 10 parts of cape jasmine fruit and 20 parts of liquorice.
Example 3
A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight: 10 parts of pilose antler, 18 parts of prepared rehmannia root, 18 parts of platycladi seed, 12 parts of Chinese magnoliavine fruit, 12 parts of Chinese angelica, 18 parts of ligusticum wallichii, 18 parts of figwort root, 18 parts of frankincense, 12 parts of honeysuckle flower, 12 parts of pseudo-ginseng, 12 parts of white paeony root, 18 parts of salvia miltiorrhiza, 12 parts of dendrobium, 18 parts of cape jasmine fruit and 12 parts of liquorice.
Example 4
A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight: 8 parts of pilose antler, 22 parts of prepared rehmannia root, 12 parts of platycladi seed, 18 parts of Chinese magnoliavine fruit, 18 parts of Chinese angelica, 12 parts of ligusticum wallichii, 12 parts of figwort root, 12 parts of frankincense, 18 parts of honeysuckle, 18 parts of pseudo-ginseng, 18 parts of white paeony root, 12 parts of salvia miltiorrhiza, 18 parts of dendrobium, 12 parts of cape jasmine fruit and 18 parts of liquorice.
Example 5
A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight: 10 parts of pilose antler, 20 parts of prepared rehmannia root, 15 parts of platycladi seed, 15 parts of Chinese magnoliavine fruit, 15 parts of Chinese angelica, 15 parts of ligusticum wallichii, 15 parts of figwort root, 15 parts of frankincense, 15 parts of honeysuckle, 15 parts of pseudo-ginseng, 15 parts of white paeony root, 15 parts of salvia miltiorrhiza, 15 parts of dendrobium, 15 parts of cape jasmine fruit and 15 parts of liquorice.
Preparation example
The preparation method of the traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases in the above embodiments 1 to 5 comprises the following steps:
(1) weighing the medicines according to the weight part ratio, and drying the medicines by a dryer respectively;
(2) crushing the dried medicine mixture by a crusher and then sieving the crushed medicine mixture by a sieve of 100-120 meshes;
(3) adding 30-40% of honey into the medicinal powder, making into honeyed pill, and sealing for storage.
The beneficial effects of the invention are specifically illustrated below in combination with clinical experimental data:
1. general data
The inventor randomly selects 50 patients with cardiovascular and cerebrovascular diseases from 3 months to 4 months in 2018 to obtain the traditional Chinese medicine composition.
2. Test method
2.1 methods of treatment
A patient orally takes the traditional Chinese medicine preparation prepared according to the embodiment 5, 50mg is taken each time, twice a day in the morning and at night, 10 days are taken as a treatment course, and 6 treatment courses are continuously taken.
2.2 Observation items: improvement of typical symptoms was observed. Typical symptoms are palpitation, shortness of breath, orthopnea, nocturnal paroxysmal dyspnea, compression or tightness pain behind the sternum, chest distress and discomfort, edema, cyanosis, syncope, cough and hemoptysis, weakness, eructation, epigastric pain, nausea and vomiting; left back pain, left arm pain.
3. Standard of therapeutic effect and therapeutic result
3.1 therapeutic criteria
The effect is shown: the symptoms of the cardiovascular and cerebrovascular diseases disappear, and the patients are recovered.
Improvement: the symptoms of cardiovascular and cerebrovascular diseases are obviously improved, and palpitation, shortness of breath, chest distress and edema are relieved and gradually return to normal.
And the invalid one can not reach the improvement standard.
3.2 treatment statistics see Table 1
TABLE 1 case treatment
Figure BDA0002955504680000051
Therefore, the medicine prepared by the preferred embodiment of the invention can safely and effectively treat the cardiovascular and cerebrovascular diseases.
According to the clinical test data, by combining the traditional Chinese medicine mechanism analysis for treating cardiovascular and cerebrovascular diseases and the common general knowledge in the field, the skilled person can easily deduce that the medicinal materials in the invention are selected within the conventional dosage range, namely, 8-12 parts of pilose antler, 15-25 parts of prepared rehmannia root, 10-20 parts of platycladi seed, 10-20 parts of Chinese magnoliavine fruit, 10-20 parts of Chinese angelica, 10-20 parts of szechuan lovage rhizome, 10-20 parts of figwort root, 10-20 parts of frankincense, 10-20 parts of honeysuckle flower, 10-20 parts of pseudo-ginseng, 10-20 parts of white paeony root, 10-20 parts of salvia miltiorrhiza, 10-20 parts of dendrobium, 10-20 parts of cape jasmine fruit and 10-20 parts of liquorice, so as to obtain the effect similar to that of the medicament prepared by the preferred embodiment of the invention.

Claims (6)

1. A traditional Chinese medicine medicament for treating cardiovascular and cerebrovascular diseases is characterized by comprising the following components in parts by weight: 8-12 parts of pilose antler, 15-25 parts of prepared rehmannia root, 10-20 parts of platycladi seed, 10-20 parts of Chinese magnoliavine fruit, 10-20 parts of Chinese angelica, 10-20 parts of ligusticum wallichii, 10-20 parts of figwort root, 10-20 parts of frankincense, 10-20 parts of honeysuckle flower, 10-20 parts of pseudo-ginseng, 10-20 parts of white paeony root, 10-20 parts of salvia miltiorrhiza, 10-20 parts of dendrobium, 10-20 parts of cape jasmine fruit and 10-20 parts of liquorice.
2. The traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases according to claim 1, which comprises the following components in parts by mass: 8-10 parts of pilose antler, 18-22 parts of prepared rehmannia root, 12-18 parts of platycladi seed, 12-18 parts of Chinese magnoliavine fruit, 12-18 parts of Chinese angelica, 12-18 parts of ligusticum wallichii, 12-18 parts of figwort root, 12-18 parts of frankincense, 12-18 parts of honeysuckle flower, 12-18 parts of pseudo-ginseng, 12-18 parts of white paeony root, 12-18 parts of salvia miltiorrhiza, 12-18 parts of dendrobium, 12-18 parts of cape jasmine fruit and 12-18 parts of liquorice.
3. The traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases according to claim 2, which comprises the following components in parts by mass: 10 parts of pilose antler, 20 parts of prepared rehmannia root, 15 parts of platycladi seed, 15 parts of Chinese magnoliavine fruit, 15 parts of Chinese angelica, 15 parts of ligusticum wallichii, 15 parts of figwort root, 15 parts of frankincense, 15 parts of honeysuckle, 15 parts of pseudo-ginseng, 15 parts of white paeony root, 15 parts of salvia miltiorrhiza, 15 parts of dendrobium, 15 parts of cape jasmine fruit and 15 parts of liquorice.
4. The preparation method of the traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases according to any one of claims 1 to 3, comprising the following steps:
(1) weighing the medicines according to the weight part ratio, and respectively drying the medicines;
(2) mixing and crushing the dried medicines, and sieving;
(3) adding honey into the medicinal powder, mixing, making into honeyed pill, and sealing for storage to obtain the Chinese medicinal preparation.
5. The method for preparing a Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases as claimed in claim 4, wherein the step (2) is carried out by sieving with 100-120 mesh sieve after pulverization.
6. The preparation method of the Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases according to claim 4, wherein the amount of honey in the step (3) is 30-40% of the total mass of the medicinal powder.
CN202110223108.7A 2021-03-01 2021-03-01 Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases and preparation method thereof Pending CN112933184A (en)

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Application publication date: 20210611