CN1129119A - Formular of Chinese medicinal capsul for auxiliary treatment of cancer and preparation method thereof - Google Patents
Formular of Chinese medicinal capsul for auxiliary treatment of cancer and preparation method thereof Download PDFInfo
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- CN1129119A CN1129119A CN 95101827 CN95101827A CN1129119A CN 1129119 A CN1129119 A CN 1129119A CN 95101827 CN95101827 CN 95101827 CN 95101827 A CN95101827 A CN 95101827A CN 1129119 A CN1129119 A CN 1129119A
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Abstract
The formular of the Chinese medicinal capsule is that: (portion) 15-30 of Xiangbalian, 15-30 of Gynostemma pentaphylla, 15-30 of the root of membranous milk vetch, 15-30 of tang straw, 15-30 of glossy ganoderma, 10-25 of tortoise plastron gelatin, 10-25 of donkey-hide gelatin and 15-30 of umbrellate pore fungus. Said medicine has the functions of nurishing body, increasing immunity, regulating white blood cell and blood platelet of patient suffering from cancer. It has the advantage of having no toxicity and less side effect.
Description
The present invention relates to a kind of prescription and preparation method of Chinese medicine, specifically is a kind of Chinese medicinal capsule prescription and preparation method that is used for auxiliary for treating cancer.
Cancer is the high disease of sickness rate on the our times, and cure rate is very low, becomes the common disease of serious harm health.Doctor trained in Western medicine is a treatment means with operation, radiotherapy, chemotherapy mainly, and after sick underwent operative, radiotherapy, the chemotherapy, deficient qi and blood appears in majority, leukopenia in the blood, symptoms such as immunologic function reduction are carried out auxiliary treatment with Western medicine, majority has certain toxic and side effects, and curative effect is also limited.
The purpose of this invention is to provide a kind of nontoxic, side effect is little, assistant treating cancer is had Chinese medicinal capsule prescription of better curative effect and preparation method thereof.
Formula components of the present invention is: fragrant eight lotus 15-30 parts, Herb Gynostemmae Pentaphylli 15-30 part, Radix Astragali 15-30 part, Herba Hedyotidis Diffusae 15-30 part, Ganoderma 15-30 part, Colla Plastri Testudinis 10-25 part, Rhizoma Atractylodis Macrocephalae 15-30 part, Colla Corii Asini 10-25 part, Polyporus 15-30 part.
Its preparation process is:
(1). the Xiang Balian in the above-mentioned prescription, Herb Gynostemmae Pentaphylli, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae are ground into 10-20 purpose smalls, put into the reflux, extract, jar, behind the adding petroleum ether dipping bath, the about 3-5 of heating and refluxing extraction hour, after the separation medicinal liquid and medicinal residues (Z1), medicinal liquid is reclaimed petroleum ether, and to get medicinal liquid (Y1) standby;
(2). above-mentioned prescription Herba Hedyotidis Diffusae, Ganoderma, Polyporus are ground into 10-20 purpose smalls, (Z1) mixes with above-mentioned medicinal residues, soaked 4-8 hour at 20 °-50 ℃ with 4-8 times of water, separate after the filtration medicinal residues (Z2) and filtrate (L2), again medicinal residues (Z2) were soaked 4-8 hour at 20 °-50 ℃ with 3-7 times of water, after the filtration medicinal residues (Z3) and filtrate (L3), after filtrate (L2) and filtrate (L3) mixing, concentrate under reduced pressure at low temperature gets filtrate (L11) to inventory, and cold preservation is standby;
(3). medicinal residues (Z3) were soaked 4-8 hour at 20 °-50 ℃ with 4-8 times of 70% ethanol, isolated by filtration gets medicinal residues (Z4) and filtrate (L4), again with medicinal residues (Z4) with 3-7 times of ethanol (70%) 20 °-50 ℃ soak filtered in 4-8 hour after, get medicinal residues (Z5) and filtrate (L5), after filtrate (L1) and filtrate (L5) mixing, decompression recycling ethanol gets filtrate (L6), and cold preservation is standby;
(4). with medicinal residues (Z5) with 3-7 times of ethanol 60 °-80 ℃ warm macerating 2-5 hour, in the reflux, extract, jar heating and refluxing extraction 2-5 hour again, filter medicinal residues (Z7) and filtrate (L7), filtrate (L7) cold preservation is standby;
(5). medicinal residues (Z7) are added 2-5 times of ethanol and transfer to PH3-5 or transfer to PH9-11 with sodium hydroxide with dilute sulfuric acid, in the reflux, extract, jar heating and refluxing extraction 1-3 hour, filter medicinal residues (Z8) and filtrate (L8), filtrate (L8) cold preservation is standby;
(6). after above filtrate (L7) and filtrate (L8) mixing, low-temperature reduced-pressure reclaims ethanol, gets filtrate (L9), and cold preservation is standby; Again the Colla Plastri Testudinis in the above-mentioned prescription, Colla Corii Asini are heated to 100 ℃ of dissolvings with 3-6 times of water, get medicinal liquid (L10);
(7). after above-mentioned filtrate (L11), filtrate (L6), filtrate (L9), filtrate (L10) mixed, pH value is transferred to neutrality, with concentrate under reduced pressure at low temperature to transferring paste, the straight empty freeze-drying of reuse, dry back powdering;
(8). medicated powder and medicinal liquid (YI) are stirred, be sub-packed in the capsule.
The present invention's prescription nourishes the body to cancer patient, the enhancing human body immunity ability, adjusting leukocyte, platelet have auxiliary treatment effect preferably, cancerous cell also there is good inhibitory effect, take avirulence for a long time, side effect is little, is that operation, radiotherapy, chemotherapy patients or cancer are cured, or physical weakness, the comparatively ideal auxiliary treatment medicine of immunocompetence decline patient.
Below in conjunction with embodiment prescription of the present invention and preparation method are further described.
Embodiment 1:
For intestinal cancer patient doctor trained in Western medicine operation back auxiliary treatment formula proportion be: 30 parts in fragrant eight lotuses, 20 parts of Herb Gynostemmae Pentaphylli, 15 parts of the Radixs Astragali, 25 parts of Herba Hedyotidis Diffusae, 15 parts of Ganodermas, 15 parts of Colla Plastri Testudiniss, 22 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts in Colla Corii Asini, 25 parts of Polyporus.
Its preparation process is: (1). the Xiang Balian in the above-mentioned prescription, Herb Gynostemmae Pentaphylli, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae are ground into 10-20 purpose smalls, put into the reflux, extract, jar, after adding the petroleum ether dipping bath, about 3.5 hours of heating and refluxing extraction, after the separation medicinal liquid and medicinal residues (Z1), medicinal liquid is reclaimed petroleum ether, and to get medicinal liquid (Y1) standby;
(2). Herba Hedyotidis Diffusae, Ganoderma, Polyporus in the above-mentioned prescription are ground into 10-20 purpose smalls, (Z1) mixes with above-mentioned medicinal residues, soaked 5 hours at 30 ℃ with 4-8 times of water, separate after the filtration medicinal residues (Z2) and filtrate (L2), again medicinal residues (Z2) were soaked 5 hours at 30 ℃ with 3-7 times of water, after the filtration medicinal residues (Z3) and filtrate (L3), after filtrate (L2) and filtrate (L3) mixing, concentrate under reduced pressure at low temperature gets filtrate (L11) to inventory, and cold preservation is standby;
(3). medicinal residues (Z3) were soaked 5 hours at 30 ℃ with 4-8 times of 70% ethanol, isolated by filtration gets medicinal residues (Z1) and filtrate (L4), again with medicinal residues (Z4) with 3-7 doubly 70% ethanol 30 ℃ soak after filtering in 5 hours medicinal residues (Z5) and filtrate (L5), after filtrate (L4) and filtrate (L5) mixing, decompression recycling ethanol, get filtrate (L6), cold preservation is standby;
(4). with medicinal residues (Z5) with 3-7 times of ethanol 60 ° of-80 ℃ of warm macerating 2.5 hours, reflux, extract, 2.5 hours in reflux, extract, again, filter medicinal residues (Z7) and filtrate (L7), filtrate (L7) cold preservation is standby;
(5). medicinal residues (Z7) are added 2-5 times of ethanol and transfer to PH3-5 or transfer to PH9-11 with sodium hydroxide with dilute sulfuric acid, reflux, extract, is 2 hours in the reflux, extract, jar, filter medicinal residues (Z8) and filtrate (L8), filtrate (L8) cold preservation is standby;
(6). after above filtrate (L7) and filtrate (L8) mixing, low-temperature reduced-pressure reclaims ethanol, gets filtrate (L9), again the Colla Plastri Testudinis in the above-mentioned prescription, Colla Corii Asini is heated to 100 ℃ of dissolvings with 3-6 times of water, gets medicinal liquid (L10);
(7). after above-mentioned filtrate (L11), filtrate (L6), filtrate (L9), filtrate (L10) mixed, pH value is transferred to neutrality, with concentrate under reduced pressure at low temperature to transferring paste, the straight empty freeze-drying of reuse, dry back powdering;
(8). medicated powder and medicinal liquid (Y1) are stirred, be sub-packed in the capsule.
Embodiment 2:
Prescription for lung cancer patient doctor trained in Western medicine operation back auxiliary treatment is: 20 parts in fragrant eight lotuses, 30 parts of Herb Gynostemmae Pentaphylli, 25 parts of the Radixs Astragali, 20 parts of Herba Hedyotidis Diffusae, 27 parts of Ganodermas, 20 parts of Colla Plastri Testudiniss, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts in Colla Corii Asini, 15 parts of Polyporus.
Its preparation process is:
(1). the Xiang Balian in the above-mentioned prescription, Herb Gynostemmae Pentaphylli, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae are ground into 10-20 purpose smalls, put into the reflux, extract, jar, behind the adding petroleum ether dipping bath, about 4.5 hours of heating and refluxing extraction, after the separation medicinal liquid and medicinal residues (Z1), medicinal liquid is reclaimed petroleum ether, and to get medicinal liquid (Y1) standby;
(2). medicinal residues (Z1) were soaked 7 hours at 50 ℃ with 4-8 times of water, separate after the filtration medicinal residues (Z2) and filtrate (L2), again medicinal residues (Z2) were soaked 7 hours at 50 ℃ with 3-7 times of water, get medicinal residues (Z3) and filtrate (L3) after the filtration, after filtrate (L2) and filtrate (L3) mixing, concentrate under reduced pressure at low temperature gets filtrate (L10) to inventory, and cold preservation is standby;
(3). medicinal residues (Z3) were soaked 7 hours at 50 ℃ with 4-8 times of 70% ethanol, isolated by filtration gets medicinal residues (Z4) and filtrate (L4), again with medicinal residues (Z4) with 3-7 doubly 70% ethanol 50 ℃ soak after filtering in 7 hours medicinal residues (Z5) and filtrate (L5), after filtrate (L4) and filtrate (L5) mixing, decompression recycling ethanol, get filtrate (L6), cold preservation is standby;
(4). with medicinal residues (Z5) with 3-7 times of ethanol 60 ° of-80 ℃ of warm macerating 4 hours, reflux, extract, 4 hours in reflux, extract, again, filter medicinal residues (Z7) and filtrate (L7), filtrate (L7) cold preservation is standby;
(5). medicinal residues (Z7) are added 2-5 times of ethanol and transfer to PH3-5 or transfer to PH9-11 with sodium hydroxide with dilute sulfuric acid, reflux, extract, is 2.5 hours in the reflux, extract, jar, filter medicinal residues (Z8) and filtrate (L8), filtrate (L8) cold preservation is standby;
(6). after above filtrate (L7) and filtrate (L8) mixed, low-temperature reduced-pressure reclaimed ethanol, filtrate (L9), and then will above filtrate (L10), filtrate (L6) and filtrate (L9) transfers to neutrality with pH value after mixing.With concentrate under reduced pressure at low temperature to transferring paste.The reuse vacuum freeze-drying method, dry back powdering;
(7). after above-mentioned filtrate (L11), filtrate (L6), filtrate (L9), filtrate (L10) mixed, pH value is transferred to neutrality, with concentrate under reduced pressure at low temperature to transferring paste, the straight empty freeze-drying of reuse, dry back powdering;
(8). medicated powder and medicinal liquid (Y1) are stirred, be sub-packed in the capsule.
Claims (7)
1. the Chinese medicinal capsule prescription and the preparation method of an auxiliary for treating cancer is characterized in that described formula components is made up of Xiang Balian, Herb Gynostemmae Pentaphylli, the Radix Astragali, Herba Hedyotidis Diffusae, Ganoderma, Colla Plastri Testudinis, the Rhizoma Atractylodis Macrocephalae, Colla Corii Asini, Polyporus.
2. Chinese medicinal capsule prescription according to claim 1 and preparation method is characterized in that described formula proportion is: fragrant eight lotus 15-30 parts, Herb Gynostemmae Pentaphylli 15-30 part, Radix Astragali 15-30 part, Herba Hedyotidis Diffusae 15-30 part, Ganoderma 15-30 part, Colla Plastri Testudinis 10-25 part, Rhizoma Atractylodis Macrocephalae 15-30 part, Colla Corii Asini 10-25 part, Polyporus 15-30 part.
3. Chinese medicinal capsule prescription according to claim 1 and 2 and preparation method is characterized in that described formula proportion is: 30 parts in fragrant eight lotuses, 20 parts of Herb Gynostemmae Pentaphylli, 15 parts of the Radixs Astragali, 25 parts of Herba Hedyotidis Diffusae, 15 parts of Ganodermas, 15 parts of Colla Plastri Testudiniss, 22 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts in Colla Corii Asini, 25 parts of Polyporus.
4. Chinese medicinal capsule prescription according to claim 1 and 2 and preparation method is characterized in that described formula proportion is: 20 parts in fragrant eight lotuses, 30 parts of Herb Gynostemmae Pentaphylli, 25 parts of the Radixs Astragali, 20 parts of Herba Hedyotidis Diffusae, 27 parts of Ganodermas, 20 parts of Colla Plastri Testudiniss, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts in Colla Corii Asini, 15 parts of Polyporus.
5. the Chinese medicinal capsule prescription and the preparation method of an auxiliary for treating cancer is characterized in that the preparation process of described Chinese medicinal capsule is:
(1). the Xiang Balian in the above-mentioned prescription, Herb Gynostemmae Pentaphylli, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae are ground into 10-20 purpose smalls, put into the reflux, extract, jar, behind the adding petroleum ether dipping bath, the about 3-5 of heating and refluxing extraction hour, after the separation medicinal liquid and medicinal residues (Z1), medicinal liquid is reclaimed petroleum ether, and to get medicinal liquid (Y1) standby;
(2). above-mentioned prescription Herba Hedyotidis Diffusae, Ganoderma, Polyporus are ground into 10-20 purpose smalls, soaked 4-8 hour at 20 °-50 ℃ with 4-8 times of water with above-mentioned medicinal residues (Z1), separate after the filtration medicinal residues (Z2) and filtrate (L2), again medicinal residues (Z2) were soaked 4-8 hour at 20 °-50 ℃ with 3-7 times of water, get medicinal residues (Z3) and filtrate (L3) after the filtration, after filtrate (L2) and filtrate (L3) mixing, concentrate under reduced pressure at low temperature is to inventory, get filtrate (L11), cold preservation is standby;
(3). medicinal residues (Z3) were soaked 4-8 hour at 20 °-50 ℃ with 4-8 times of 70% ethanol, isolated by filtration gets medicinal residues (Z4) and filtrate (L4), again with medicinal residues (Z4) with 3-7 times of ethanol (70%) 20 °-50 ℃ soak filtered in 4-8 hour after, get medicinal residues (Z5) and filtrate (L5), after filtrate (L4) and filtrate (L5) mixing, decompression recycling ethanol gets filtrate (L6), and cold preservation is standby;
(4). with medicinal residues (Z5) with 3-7 times of ethanol 60 °-80 ℃ warm macerating 2-5 hour, in the reflux, extract, jar heating and refluxing extraction 2-5 hour again, filter medicinal residues (Z7) and filtrate (L7), filtrate (L7) cold preservation is standby;
(5). medicinal residues (Z7) are added 2-5 times of ethanol and transfer to PH3-5 or transfer to PH9-11 with sodium hydroxide with dilute sulfuric acid, in the reflux, extract, jar heating and refluxing extraction 1-3 hour, filter medicinal residues (Z8) and filtrate (L8), filtrate (L8) cold preservation is standby;
(6). after above filtrate (L7) and filtrate (L8) mixing, low-temperature reduced-pressure reclaims ethanol, gets filtrate (L9), and cold preservation is standby; Again the Colla Plastri Testudinis in the above-mentioned prescription, Colla Corii Asini are heated to 100 ℃ of dissolvings with 3-6 times of water, get medicinal liquid (L10);
(7). after above-mentioned filtrate (L11), filtrate (L6), filtrate (L9), filtrate (L10) mixed, pH value is transferred to neutrality, with concentrate under reduced pressure at low temperature to transferring paste, the straight empty freeze-drying of reuse, dry back powdering;
(8). medicated powder and medicinal liquid (YI) are stirred, be sub-packed in the capsule.
6. the Chinese medicinal capsule prescription and the preparation method of auxiliary for treating cancer according to claim 5 is characterized in that the preparation process of described Chinese medicinal capsule is:
(1). the Xiang Balian in the above-mentioned prescription, Herb Gynostemmae Pentaphylli, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae are ground into 10-20 purpose smalls, put into the reflux, extract, jar, behind the adding petroleum ether dipping bath, about 3.5 hours of heating and refluxing extraction, after the separation medicinal liquid and medicinal residues (Z1), medicinal liquid is reclaimed petroleum ether, and to get medicinal liquid (Y1) standby;
(2). above-mentioned prescription Herba Hedyotidis Diffusae, Ganoderma, Polyporus are ground into 10-20 purpose smalls, (Z1) mixes with above-mentioned medicinal residues, soaked 5 hours at 30 ℃ with 4-8 times of water, separate after the filtration medicinal residues (Z2) and filtrate (L2), again medicinal residues (Z2) were soaked 5 hours at 30 ℃ with 3-7 times of water, after the filtration medicinal residues (Z3) and filtrate (L3), after filtrate (L2) and filtrate (L3) mixing, concentrate under reduced pressure at low temperature gets filtrate (L11) to inventory, and cold preservation is standby;
(3). medicinal residues (Z3) were soaked 5 hours at 30 ℃ with 4-8 times of 70% ethanol, isolated by filtration gets medicinal residues (Z4) and filtrate (L4), again with medicinal residues (Z4) with 3-7 doubly 70% ethanol 30 ℃ soak after filtering in 5 hours medicinal residues (Z5) and filtrate (L5), after filtrate (L4) and filtrate (L5) mixing, decompression recycling ethanol, get filtrate (L6), cold preservation is standby;
(4). with medicinal residues (Z5) with 3-7 times of ethanol 60 ° of-80 ℃ of warm macerating 2.5 hours, reflux, extract, 2.5 hours in reflux, extract, again, filter medicinal residues (Z7) and filtrate (L7), filtrate (L7) cold preservation is standby;
(5). medicinal residues (Z7) are added 2-5 times of ethanol and transfer to PH3-5 or transfer to PH9-11 with sodium hydroxide with dilute sulfuric acid, reflux, extract, is 2 hours in the reflux, extract, jar, filter medicinal residues (Z8) and filtrate (L8), filtrate (L8) cold preservation is standby;
(6). after above filtrate (L7) and filtrate (L8) mixing, low-temperature reduced-pressure reclaims ethanol, gets filtrate (L9), again the Colla Plastri Testudinis in the above-mentioned prescription, Colla Corii Asini is heated to 100 ℃ of dissolvings with 3-6 times of water, gets medicinal liquid (L10);
(7). after above-mentioned filtrate (L11), filtrate (L6), filtrate (L9), filtrate (L10) mixed, pH value is transferred to neutrality, with concentrate under reduced pressure at low temperature to transferring paste, the straight empty freeze-drying of reuse, dry back powdering;
(8). medicated powder and medicinal liquid (Y1) are stirred, be sub-packed in the capsule.
7. the Chinese medicinal capsule prescription and the preparation method of auxiliary for treating cancer according to claim 5 is characterized in that the preparation process of described Chinese medicinal capsule is:
(1). the Xiang Balian in the above-mentioned prescription, Herb Gynostemmae Pentaphylli, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae are ground into 10-20 purpose smalls, put into the reflux, extract, jar, behind the adding petroleum ether dipping bath, about 4.5 hours of heating and refluxing extraction, after the separation medicinal liquid and medicinal residues (Z1), medicinal liquid is reclaimed petroleum ether, and to get medicinal liquid (Y1) standby;
(2). medicinal residues (Z1) were soaked 7 hours at 50 ℃ with 4-8 times of water, separate after the filtration medicinal residues (Z2) and filtrate (L2), again medicinal residues (Z2) were soaked 7 hours at 50 ℃ with 3-7 times of water, get medicinal residues (Z3) and filtrate (L3) after the filtration, after filtrate (L2) and filtrate (L3) mixing, concentrate under reduced pressure at low temperature gets filtrate (L10) to inventory, and cold preservation is standby;
(3). medicinal residues (Z3) were soaked 7 hours at 50 ℃ with 4-8 times of 70% ethanol, isolated by filtration gets medicinal residues (Z4) and filtrate (L4), again with medicinal residues (Z4) with 3-7 doubly 70% ethanol 50 ℃ soak after filtering in 7 hours medicinal residues (Z5) and filtrate (L5), after filtrate (L4) and filtrate (L5) mixing, decompression recycling ethanol, get filtrate (L6), cold preservation is standby;
(4). with medicinal residues (Z5) with 3-7 times of ethanol 60 ° of-80 ℃ of warm macerating 4 hours, reflux, extract, 4 hours in reflux, extract, again, filter medicinal residues (Z7) and filtrate (L7), filtrate (L7) cold preservation is standby;
(5). medicinal residues (Z7) are added 2-5 times of ethanol and transfer to PH3-5 or transfer to PH9-11 with sodium hydroxide with dilute sulfuric acid, reflux, extract, is 2.5 hours in the reflux, extract, jar, filter medicinal residues (Z8) and filtrate (L8), filtrate (L8) cold preservation is standby;
(6). after above filtrate (L7) and filtrate (L8) mixed, low-temperature reduced-pressure reclaimed ethanol, filtrate (L9), and then will above filtrate (L10), filtrate (L6) and filtrate (L9) transfers to neutrality with pH value after mixing.With concentrate under reduced pressure at low temperature to transferring paste.The reuse vacuum freeze-drying method, dry back powdering;
(7). after above-mentioned filtrate (L11), filtrate (L6), filtrate (L9), filtrate (L10) mixed, pH value is transferred to neutrality, with concentrate under reduced pressure at low temperature to transferring paste, the straight empty freeze-drying of reuse, dry back powdering;
(8). medicated powder and medicinal liquid (Y1) are stirred, be sub-packed in the capsule.
Priority Applications (1)
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CN 95101827 CN1129119A (en) | 1995-02-16 | 1995-02-16 | Formular of Chinese medicinal capsul for auxiliary treatment of cancer and preparation method thereof |
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CN 95101827 CN1129119A (en) | 1995-02-16 | 1995-02-16 | Formular of Chinese medicinal capsul for auxiliary treatment of cancer and preparation method thereof |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104223056A (en) * | 2013-06-17 | 2014-12-24 | 湖北老中醫制药有限责任公司 | Application of tortoise-shell glue to preparation of medicine for treating tumors |
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1995
- 1995-02-16 CN CN 95101827 patent/CN1129119A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104223056A (en) * | 2013-06-17 | 2014-12-24 | 湖北老中醫制药有限责任公司 | Application of tortoise-shell glue to preparation of medicine for treating tumors |
CN104223056B (en) * | 2013-06-17 | 2018-11-30 | 湖北老中醫制药有限责任公司 | Purposes of the colla carapacis et plastri testudinis in the drug of preparation treatment tumour |
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