CN112870302A - Desensitizer for effective desensitization and processing technology thereof - Google Patents

Desensitizer for effective desensitization and processing technology thereof Download PDF

Info

Publication number
CN112870302A
CN112870302A CN202110121894.XA CN202110121894A CN112870302A CN 112870302 A CN112870302 A CN 112870302A CN 202110121894 A CN202110121894 A CN 202110121894A CN 112870302 A CN112870302 A CN 112870302A
Authority
CN
China
Prior art keywords
weight
parts
agent
fixedly connected
stirring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110121894.XA
Other languages
Chinese (zh)
Inventor
李雅镰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Kelide Daily Chemical Technology Co ltd
Original Assignee
Guangzhou Kelide Daily Chemical Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Kelide Daily Chemical Technology Co ltd filed Critical Guangzhou Kelide Daily Chemical Technology Co ltd
Priority to CN202110121894.XA priority Critical patent/CN112870302A/en
Publication of CN112870302A publication Critical patent/CN112870302A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/23Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by the orientation or disposition of the rotor axis
    • B01F27/232Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by the orientation or disposition of the rotor axis with two or more rotation axes
    • B01F27/2322Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by the orientation or disposition of the rotor axis with two or more rotation axes with parallel axes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/85Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with two or more stirrers on separate shafts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/90Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with paddles or arms 
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J4/00Feed or outlet devices; Feed or outlet control devices
    • B01J4/001Feed or outlet devices as such, e.g. feeding tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48Thickener, Thickening system
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2204/00Aspects relating to feed or outlet devices; Regulating devices for feed or outlet devices
    • B01J2204/002Aspects relating to feed or outlet devices; Regulating devices for feed or outlet devices the feeding side being of particular interest
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2204/00Aspects relating to feed or outlet devices; Regulating devices for feed or outlet devices
    • B01J2204/007Aspects relating to the heat-exchange of the feed or outlet devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides an effective desensitizing desensitizer and a processing technology thereof, wherein raw materials comprise 5 parts by weight of skin beautifying agent, 2 parts by weight of moisturizing agent and 3 parts by weight of antiallergic agent, the 5 parts by weight of skin beautifying agent comprise 0.5 part by weight of thickening agent, 0.5 part by weight of allantoin, 2 parts by weight of nicotinamide, 1 part by weight of tranexamic acid and 1 part by weight of 4-methoxy potassium salicylate, and the 2 parts by weight of moisturizing agent comprise 1 part by weight of deionized water grease, 0.2 part by weight of coix seed powder, 0.25 part by weight of aloe essential oil, 0.25 part by weight of green tea seed essential oil, 0.2 part by weight of lucid ganoderma powder and 0.1 part by weight of emulsifying agent. The desensitizer for effective desensitization and the processing technology thereof provided by the invention are prepared into antiallergic components by using the kava root extract, the giant knotweed rhizome extract and the oat extract in parts by weight, so that the desensitizer can lubricate skin while achieving the antiallergic effect.

Description

Desensitizer for effective desensitization and processing technology thereof
Technical Field
The invention relates to the field of allergy, in particular to an effective desensitizer and a processing technology thereof.
Background
Normally, when foreign substances enter the human body, most of them face two fates, if they are recognized as useful or harmless substances by the body, they will harmoniously interact with the human body and will be absorbed, utilized or naturally discharged, if they are recognized as harmful substances, the immune system of the body will immediately react to expel or destroy them, which is the protective effect exerted by the immune response, which is one of the important functions of the human defense system, but if the response exceeds the normal range, i.e. the immune system attacks the harmless substances, this condition is called allergic reaction, which is a disease, because the healthy body tissues are also damaged by the non-terminal attack, even if the immune system attacks and destroys the tissues of the body itself, which is very unfavorable for the health of the human body.
In the use process of the desensitizer in the market, the irritability to the allergic part of a patient is large, the emotion of the patient is influenced, the effect of the desensitizer cannot be fully exerted, the recovery of the patient is influenced, and the common desensitizer does not have the function of skin care, so that the allergy of the patient can be consistent with other parts after being desensitized by subsequent maintenance, the face appearance of the patient is influenced, and the treatment period is prolonged to a certain extent.
Therefore, there is a need to provide a desensitizing agent for effective desensitization and a processing method thereof to solve the above technical problems.
Disclosure of Invention
The invention provides an effective desensitizer and a processing technology thereof, which solve the problem that the allergy of a patient can be consistent with other places after desensitization by using a traditional desensitizer which has large irritation to the allergic part of the patient and does not have the function of skin care.
In order to solve the technical problem, the raw materials of the desensitizer for effective desensitization provided by the invention comprise 5 parts by weight of a skin beautifying agent, 2 parts by weight of a water replenishing agent and 3 parts by weight of an antiallergic agent.
Preferably, the 5 parts by weight of the skin beautifying agent comprises 0.5 part by weight of the thickening agent, 0.5 part by weight of allantoin, 2 parts by weight of nicotinamide, 1 part by weight of tranexamic acid and 1 part by weight of 4-methoxysalicylic acid potassium salt.
Preferably, the 2 parts by weight of water replenishing agent comprises 1 part by weight of deionized water grease, 0.2 part by weight of coix seed powder, 0.25 part by weight of aloe essential oil, 0.25 part by weight of green tea seed essential oil, 0.2 part by weight of ganoderma lucidum powder and 0.1 part by weight of emulsifier.
Preferably, the 3 parts by weight of the antiallergic agent includes 1 part by weight of kava root extract, 1 part by weight of giant knotweed rhizome extract and 1 part by weight of oat extract.
A process for the manufacture of a desensitizing agent for effective desensitization comprising the steps of:
s1, adding 0.5 weight part of thickening agent into water in a reaction kettle filled with water, stirring uniformly until the mixture is transparent, adding 0.5 weight part of allantoin, 2 weight parts of nicotinamide, 1 weight part of tranexamic acid and 1 weight part of 4-methoxy potassium salicylate, heating and stirring, and keeping the temperature for a period of time to obtain a phase A;
s2, adding caprylic/capric triglyceride, sorbitan stearate, coco glyceride and deionized water into a reaction kettle, heating to 50-60 ℃ under the pressure of 0.1-0.3 Mpa, and stirring for a certain time to obtain deionized water grease;
s3, adding 0.2 weight part of coix seed powder, 0.25 weight part of aloe essential oil, 0.25 weight part of green tea seed essential oil, 0.2 weight part of ganoderma lucidum powder, 0.1 weight part of emulsifier, 1 weight part of kava root extract, 1 weight part of polygonum cuspidatum extract and 1 weight part of oat extract into the deionized water grease, and stirring for 20-30 min at a constant temperature to obtain a phase B;
and S4, adding the phase B into the phase A, stirring for 8-12min, homogenizing for 2-5min, stirring for 26-33min until complete emulsification, cooling to 36-41 ℃, and adding a pH regulator to obtain the phase AB.
S5, adding the bacillus fermentation product and the preservative into the AB phase obtained in the step S4, and stirring for 26-33min to obtain the finished desensitizer.
Preferably, in the step S1, the stirring temperature of the phase a solution is 71-75 ℃, and the holding time after the stirring is completed is 10-20 min.
Preferably, in the step S2, the stirring time is 1 to 2H.
Preferably, a reaction kettle is required to be used in the processing process of the step S1, the reaction kettle comprises a heat preservation reaction kettle, a feeding pipe is arranged at the top of the heat preservation reaction kettle, a heat preservation box is fixedly connected to the top of the heat preservation reaction kettle, the top end of the feeding pipe penetrates into the heat preservation box, a mixing box is fixedly connected to the top of the heat preservation box, feeding pipes are respectively communicated with two sides of the top of the mixing box, pistons are respectively arranged at the outer ends of the two feeding pipes, a mixing device is arranged at the top of the mixing box, connecting pipes are respectively communicated with two sides of the bottom of the mixing box, the bottom ends of the two connecting pipes penetrate into the heat preservation box, clamping plates are respectively fixedly connected to two sides of the top of the inner wall of the heat preservation box, a first electric telescopic rod is respectively fixedly connected to one side where the two clamping plates are separated, a baffle plate, the top of the inner wall of the heat insulation box is fixedly connected with a second electric telescopic rod, and the bottom end of the second electric telescopic rod is fixedly connected with a sealing plug matched with the feeding pipe.
Preferably, mixing arrangement includes the motor, the output shaft fixedly connected with double rule belt pulley of motor, the surface of double track belt pulley is connected with first belt pulley and second belt pulley through the belt transmission respectively, the equal fixedly connected with axis of rotation of axle center department of first belt pulley and second belt pulley, two the bottom of axis of rotation rotationally all runs through to the inside of mixing box, two the equal fixedly connected with stirring leaf in surface of axis of rotation.
Compared with the related technology, the desensitizer for effective desensitization and the processing technology thereof provided by the invention have the following beneficial effects:
the invention provides an effective desensitizer and a processing technology thereof,
1. the anti-allergic component in the desensitizer is prepared by using the kava root extract, the giant knotweed extract and the oat extract in parts by weight, the oat extract has obvious curative effect on allergic skin, can improve the lubricity of the skin, and relieve the irritation of severe environment to the skin and the pain and itch of the skin caused by eczema, so that the skin is lubricated while the anti-allergic effect is achieved, and the kava root extract can play various physiological effects of calming and hypnotizing, calming the mood, relieving the depression feeling and the like, so that the mood of a user of the desensitizer is more relaxed, the allergic symptoms are further favorably relieved, the giant knotweed extract mainly comprises resveratrol and emodin, the resveratrol is shown to be beneficial to cardiovascular health and blood circulation, the pain is relieved, the heat is cleared away and the dampness is removed, so that the irritation to allergic part of a patient when the desensitizer is used, thereby making the desensitizer more comfortable to use.
2. Through the insulation can, second electric telescopic handle, the setting of devices such as sealing plug, when adding the raw materials in to insulation reaction kettle 1, can keep in the insulation can with the raw materials earlier, open the sealing plug again in the insulation can with the raw materials leading-in, make insulation reaction kettle 1 pass through the insulation can when adding the raw materials and external isolated, reduce the temperature loss in insulation reaction kettle 1, make insulation reaction kettle 1 maintain the required energy of constant temperature and reduce, reach energy-conserving effect, and through mixing box and mixing arrangement's setting, can premix when adding the raw materials, make the multiple raw materials after the mixture can more fast and more even react with the solution in the insulation reaction kettle when adding in the insulation reaction kettle, thereby make this desensitizer processing faster.
Drawings
FIG. 1 is a schematic structural view of a preferred embodiment of the effective desensitizing agent and process of making the same according to the present invention;
FIG. 2 is a schematic sectional structure view of a thermal insulation reaction kettle;
fig. 3 is a schematic structural view of the mixing device.
Reference numbers in the figures: 1. the device comprises a heat preservation reaction kettle, 2, a feeding pipe, 3, a heat preservation box, 4, a mixing box, 5, a mixing device, 501, a motor, 502, a double-track belt pulley, 503, a first belt pulley, 504, a second belt pulley, 505, a rotating shaft, 506, a stirring blade, 6, a connecting pipe, 7, a clamping plate, 8, a first electric telescopic rod, 9, a baffle, 10, a second electric telescopic rod, 11, a sealing plug, 12, a feeding pipe, 13 and a piston.
Detailed Description
The invention is further described with reference to the following figures and embodiments.
The desensitizer for effective desensitization is prepared from 5 weight parts of skin beautifying agent, 2 weight parts of water replenishing agent and 3 weight parts of antiallergic agent.
The 5 parts by weight of skin beautifying agent comprises 0.5 part by weight of thickening agent, 0.5 part by weight of allantoin, 2 parts by weight of nicotinamide, 1 part by weight of tranexamic acid and 1 part by weight of 4-methoxy potassium salicylate.
The skin beautifying agent with proper proportion enables the desensitizer to have the function of whitening skin, and the nicotinamide can accelerate metabolism and promote the exfoliation of melanocyte containing melanin; the tranexamic acid has effects of whitening skin, removing speckle, removing chloasma, removing sunburn, preventing skin from tanning, preventing pachylosis, removing horny dead skin, caring skin, eliminating wrinkle, relieving inflammation, resisting allergy, and stopping bleeding; the 4-methoxy potassium salicylate is a multifunctional accelerator for removing freckles, whitening and tendering skin, can meet the requirements of skin care products on skin whitening, freckles and pigments removal and elimination of waste dead skin and wrinkles of skin, has various biological activity functions, can remarkably accelerate and promote the skin whitening of all types of human bodies, fade spot pigments and wrinkles, generate smooth and clean skin, improve abnormal keratinization of the skin, enable the keratinization metabolism of the skin to be normal, and accelerate the removal of melanin.
The 2 parts by weight of moisturizing agent comprises 1 part by weight of deionized water grease, 0.2 part by weight of coix seed powder, 0.25 part by weight of aloe essential oil, 0.25 part by weight of green tea seed essential oil, 0.2 part by weight of ganoderma lucidum powder and 0.1 part by weight of emulsifier.
The deionized water grease is composed of caprylic/capric triglyceride, sorbitan stearate, coconut acid glycerol and deionized water in parts by weight, the aloe essential oil and the green tea seed essential oil are used as main water replenishing components, the coix seed powder and the ganoderma lucidum powder are used as water locking and antioxidant components, the aloe oil and the green tea seed essential oil are light and thin and not greasy, can be quickly absorbed by skin, and a thin coating layer can keep water locking and not drying all day long, so that the phenomena of allergy, desquamation and the like caused by dry and itchy skin are avoided.
The 3 parts by weight of the antiallergic agent comprises 1 part by weight of kava root extract, 1 part by weight of giant knotweed rhizome extract and 1 part by weight of oat extract.
The oat extract oat has obvious curative effect on allergic skin, can improve the lubricity of the skin, and relieves the irritation of severe environment to the skin and the pain and itch of the skin caused by eczema, thereby achieving the anti-allergic effect and lubricating the skin at the same time, and the kava root extract can play a plurality of physiological effects of calming and hypnotizing, calming the mood, relieving the depression and the like, so that the mood of a user of the desensitizer is relieved, and the allergic symptom is further relieved.
A process for the manufacture of a desensitizing agent for effective desensitization comprising the steps of:
s1, adding 0.5 weight part of thickening agent into water in a reaction kettle filled with water, stirring uniformly until the mixture is transparent, adding 0.5 weight part of allantoin, 2 weight parts of nicotinamide, 1 weight part of tranexamic acid and 1 weight part of 4-methoxy potassium salicylate, heating and stirring, and keeping the temperature for a period of time to obtain a phase A;
s2, adding caprylic/capric triglyceride, sorbitan stearate, coco glyceride and deionized water into a reaction kettle, heating to 50-60 ℃ under the pressure of 0.1-0.3 Mpa, and stirring for a certain time to obtain deionized water grease;
s3, adding 0.2 weight part of coix seed powder, 0.25 weight part of aloe essential oil, 0.25 weight part of green tea seed essential oil, 0.2 weight part of ganoderma lucidum powder, 0.1 weight part of emulsifier, 1 weight part of kava root extract, 1 weight part of polygonum cuspidatum extract and 1 weight part of oat extract into the deionized water grease, and stirring for 20-30 min at a constant temperature to obtain a phase B;
s4, adding the phase B into the phase A, stirring for 8-12min, homogenizing for 2-5min, stirring for 26-33min until complete emulsification, cooling to 36-41 ℃, and adding a pH regulator to obtain the phase AB;
s5, adding the bacillus fermentation product and the preservative into the AB phase obtained in the step S4, and stirring for 26-33min to obtain the finished desensitizer.
In step S1, the stirring temperature of the solution of phase a is 71-75 ℃, the holding time after the stirring is completed is 10-20min, and at the temperature of 71-75 ℃, the solubility of each solute of the solution of phase a is higher, and the solution components are more saturated, so that the raw materials can be more fully utilized, and the whitening effect of each solute can be fully exerted.
In the step S2, stirring for 1-2H to fully mix caprylic/capric triglyceride, sorbitan stearate and coconut acid glycerol with deionized water.
The reaction kettle is required to be used in the processing process of the step S1 and comprises a heat preservation reaction kettle 1, devices such as heat preservation, pressure control and stirring are arranged in the heat preservation reaction kettle 1, the top of the heat preservation reaction kettle 1 is provided with an inlet pipe 2, the top of the heat preservation reaction kettle 1 is fixedly connected with a heat preservation box 3, the top end of the inlet pipe 2 penetrates through the inside of the heat preservation box 3, the top of the heat preservation box 3 is fixedly connected with a mixing box 4, the heat preservation box 3 and the mixing box 4 are made of heat insulation materials, inclined plates are arranged in the heat preservation box 3 and the mixing box 4, and raw material residues are placed.
The both sides at 4 tops of mixing box all communicate there is filling tube 12, two the outer end of filling tube 12 all is provided with piston 13, the top of mixing box 4 is provided with mixing arrangement 5, the both sides of 4 bottoms of mixing box all communicate there is connecting pipe 6, two the bottom of connecting pipe 6 all runs through to the inside of insulation can 3, the equal fixedly connected with cardboard 7 in both sides at 3 inner wall tops of insulation can, two the equal fixedly connected with first electric telescopic handle 8 in one side that cardboard 7 leaves mutually, two the equal fixedly connected with baffle 9 of one end that first electric telescopic handle 8 leaves mutually, the top fixedly connected with second electric telescopic handle 10 of 3 inner walls of insulation can, the bottom fixedly connected with of second electric telescopic handle 10 with the sealing plug 11 of 2 looks adaptations of inlet pipe.
Through insulation can 3, second electric telescopic handle 10, the setting of devices such as sealing plug 11, when adding the raw materials in insulation reaction kettle 1, can keep in the insulation can 3 with the raw materials earlier, open sealing plug 11 again in insulation can 3 with the raw materials leading-in, make insulation reaction kettle 1 completely cut off with external through insulation can 3 when adding the raw materials, reduce the temperature loss in insulation reaction kettle 1, make insulation reaction kettle 1 maintain the required energy reduction of constant temperature, reach energy-conserving effect.
Mixing arrangement 5 includes motor 501, motor 501's output shaft fixedly connected with double rule belt pulley 502, the surface of double-track belt pulley 502 is connected with first belt pulley 503 and second belt pulley 504 through the belt transmission respectively, the equal fixedly connected with axis of rotation 505 in axle center department of first belt pulley 503 and second belt pulley 504, two the bottom of axis of rotation 505 rotationally all runs through to the inside of mixing box 4, two the equal fixedly connected with stirring leaf 506 in surface of axis of rotation 505.
Through the setting of mixing box 4 and mixing arrangement 5, can premix when adding the raw materials for multiple raw materials after the mixture can be faster and more even when adding in heat preservation reation kettle 1 react with the solution in the heat preservation reation kettle 1, thereby make each raw materials and solution mix more fully and even.
The working principle of the desensitizer for effective desensitization and the processing technology thereof provided by the invention is as follows:
when raw materials need to be added, the pistons 13 on the two feeding pipes 12 are pulled out, the raw materials are introduced into the mixing box 4 through the feeding pipes 12, then the pistons are covered, meanwhile, the mixing device 5 is started, the motor 501 drives the double-track belt pulley 502 to rotate, the double-track belt pulley 502 drives the first belt pulley 503 and the second belt pulley 504 to rotate, the first belt pulley 503 and the second belt pulley 504 rotate to drive the two rotating shafts 505 to rotate, the two rotating shafts 505 drive the two stirring blades 506 to rotate, the raw materials in the mixing box 4 are fully mixed, then the two first electric telescopic rods 8 are contracted to drive the two baffles 9 to move oppositely, the two baffles 9 are separated from the connecting pipe 6, the connecting pipe 6 is opened, the mixed raw materials enter the insulation box 3, the first electric telescopic rods 8 are reset to seal the connecting pipe 6, and then the second electric telescopic rods 10 are contracted to drive the sealing plugs 11 to move, so that the feed pipe 12 is opened, and the raw materials are introduced into the heat-preservation reaction kettle 1 for processing.
Compared with the related technology, the desensitizer for effective desensitization and the processing technology thereof provided by the invention have the following beneficial effects:
1. the anti-allergic component in the desensitizer is prepared by using the kava root extract, the giant knotweed extract and the oat extract in parts by weight, the oat extract has obvious curative effect on allergic skin, can improve the lubricity of the skin, and relieve the irritation of severe environment to the skin and the pain and itch of the skin caused by eczema, so that the skin is lubricated while the anti-allergic effect is achieved, and the kava root extract can play various physiological effects of calming and hypnotizing, calming the mood, relieving the depression feeling and the like, so that the mood of a user of the desensitizer is more relaxed, the allergic symptoms are further favorably relieved, the giant knotweed extract mainly comprises resveratrol and emodin, the resveratrol is shown to be beneficial to cardiovascular health and blood circulation, the pain is relieved, the heat is cleared away and the dampness is removed, so that the irritation to allergic part of a patient when the desensitizer is used, thereby making the desensitizer more comfortable to use.
2. Through insulation can 3, second electric telescopic handle 10, the setting of devices such as sealing plug 11, when adding the raw materials in insulation reaction kettle 1, can keep in the insulation can 3 with the raw materials earlier, it is leading-in with the raw materials to open sealing plug 11 in insulation can 3 again, make insulation reaction kettle 1 pass through insulation can 3 and external isolated when adding the raw materials, reduce the temperature loss in insulation reaction kettle 1, make insulation reaction kettle 1 maintain the required energy reduction of constant temperature, reach energy-conserving effect, and through mixing box 4 and mixing arrangement 5's setting, can mix in advance when adding the raw materials, make the multiple raw materials after the mixture can more fast and more even react with the solution in insulation reaction kettle 1 when adding insulation reaction kettle 1, thereby make each raw materials and solution mix more fully and evenly.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by using the contents of the present specification and the accompanying drawings, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims (9)

1. A desensitizer for effective desensitization is characterized in that raw materials comprise 5 parts by weight of a skin beautifying agent, 2 parts by weight of a water replenishing agent and 3 parts by weight of an antiallergic agent.
2. Desensitizing agent to effective desensitization according to claim 1, wherein said 5 parts by weight of skin-beautifying agent comprise 0.5 parts by weight of thickening agent, 0.5 parts by weight of allantoin, 2 parts by weight of niacinamide, 1 part by weight of tranexamic acid and 1 part by weight of potassium 4-methoxysalicylate.
3. Desensitizing agent to effective desensitization according to claim 1, wherein said 2 parts by weight of moisturizing agent comprise 1 part by weight of deionized water oil and fat, 0.2 parts by weight of coix seed powder, 0.25 parts by weight of aloe vera essential oil, 0.25 parts by weight of green tea seed essential oil, 0.2 parts by weight of ganoderma lucidum powder and 0.1 parts by weight of emulsifier.
4. Desensitizing agent to effective desensitization according to claim 1, wherein said 3 parts by weight of antiallergic agent comprises 1 part by weight of kava root extract, 1 part by weight of giant knotweed extract and 1 part by weight of oat extract.
5. A process for the manufacture of a desensitizing agent effective for desensitization comprising the steps of:
s1, adding 0.5 weight part of thickening agent into water in a reaction kettle filled with water, stirring uniformly until the mixture is transparent, adding 0.5 weight part of allantoin, 2 weight parts of nicotinamide, 1 weight part of tranexamic acid and 1 weight part of 4-methoxy potassium salicylate, heating and stirring, and keeping the temperature for a period of time to obtain a phase A;
s2, adding caprylic/capric triglyceride, sorbitan stearate, coco glyceride and deionized water into a reaction kettle, heating to 50-60 ℃ under the pressure of 0.1-0.3 Mpa, and stirring for a certain time to obtain deionized water grease;
s3, adding 0.2 weight part of coix seed powder, 0.25 weight part of aloe essential oil, 0.25 weight part of green tea seed essential oil, 0.2 weight part of ganoderma lucidum powder, 0.1 weight part of emulsifier, 1 weight part of kava root extract, 1 weight part of polygonum cuspidatum extract and 1 weight part of oat extract into the deionized water grease, and stirring for 20-30 min at a constant temperature to obtain a phase B;
s4, adding the phase B into the phase A, stirring for 8-12min, homogenizing for 2-5min, stirring for 26-33min until complete emulsification, cooling to 36-41 ℃, and adding a pH regulator to obtain the phase AB;
s5, adding the bacillus fermentation product and the preservative into the AB phase obtained in the step S4, and stirring for 26-33min to obtain the finished desensitizer.
6. A process for the manufacture of a desensitizing agent to effective desensitization according to claim 5, wherein in step S1, the temperature of agitation of the phase A solution is 71-75 ℃ and the incubation time after completion of agitation is 10-20 min.
7. The process of claim 1, wherein in step S2, the stirring time is 1-2H.
8. The process for processing desensitizer to effective desensitization according to claim 5, wherein a reaction kettle is required in the processing of step S1, the reaction kettle comprises a thermal insulation reaction kettle (1), a feeding pipe (2) is disposed at the top of the thermal insulation reaction kettle (1), a thermal insulation box (3) is fixedly connected to the top of the thermal insulation reaction kettle (1), the top end of the feeding pipe (2) penetrates into the thermal insulation box (3), a mixing box (4) is fixedly connected to the top of the thermal insulation box (3), feeding pipes (12) are respectively connected to both sides of the top of the mixing box (4), pistons (13) are respectively disposed at the outer ends of the two feeding pipes (12), a mixing device (5) is disposed at the top of the mixing box (4), and connecting pipes (6) are respectively connected to both sides of the bottom of the mixing box (4), the bottom of two connecting pipe (6) all runs through to the inside of insulation can (3), the equal fixedly connected with cardboard (7) in both sides at insulation can (3) inner wall top, two the equal fixedly connected with first electric telescopic handle (8) of one side that cardboard (7) leave mutually, two the equal fixedly connected with baffle (9) of one end that first electric telescopic handle (8) leave mutually, the top fixedly connected with second electric telescopic handle (10) of insulation can (3) inner wall, the bottom fixedly connected with of second electric telescopic handle (10) with sealing plug (11) of inlet pipe (2) looks adaptation.
9. The process for the desensitization of claim 8, wherein said mixing device (5) comprises an electric motor (501), said electric motor (501) has an output shaft fixedly connected to a double-gauge pulley (502), said double-gauge pulley (502) has a surface drivingly connected to a first pulley (503) and a second pulley (504) via a belt, said first pulley (503) and said second pulley (504) have axes fixedly connected to a rotating shaft (505), said two rotating shafts (505) have bottom ends rotatably penetrating into said mixing box (4), and said two rotating shafts (505) have surfaces fixedly connected to a stirring blade (506).
CN202110121894.XA 2021-01-28 2021-01-28 Desensitizer for effective desensitization and processing technology thereof Pending CN112870302A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110121894.XA CN112870302A (en) 2021-01-28 2021-01-28 Desensitizer for effective desensitization and processing technology thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110121894.XA CN112870302A (en) 2021-01-28 2021-01-28 Desensitizer for effective desensitization and processing technology thereof

Publications (1)

Publication Number Publication Date
CN112870302A true CN112870302A (en) 2021-06-01

Family

ID=76053287

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110121894.XA Pending CN112870302A (en) 2021-01-28 2021-01-28 Desensitizer for effective desensitization and processing technology thereof

Country Status (1)

Country Link
CN (1) CN112870302A (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853301A (en) * 2016-05-26 2016-08-17 彭之玉 Biological polypeptide repairing essence
CN107974267A (en) * 2017-11-28 2018-05-01 合肥宏润环保科技有限公司 A kind of device of food and drink greasy dirt recycling for commercial Application
CN108854911A (en) * 2018-07-17 2018-11-23 芜湖芬特勘测服务有限公司 A kind of chemical industry equipment reaction kettle
CN109125201A (en) * 2017-06-19 2019-01-04 周霞 A kind of preparation method of long-acting water lock body lotion
CN110448518A (en) * 2019-08-21 2019-11-15 西安博和医疗科技有限公司 A kind of preparation method of whitening body lotion
CN111790337A (en) * 2020-07-09 2020-10-20 江西德盛精细化学品有限公司 Acid fixation agent produces and uses reation kettle
CN211754853U (en) * 2019-11-29 2020-10-27 贵州天时佳利能源开发有限责任公司 Low temperature reation kettle's heat preservation equipment
CN211800813U (en) * 2020-01-19 2020-10-30 上海福岛新材料科技有限公司 Energy-concerving and environment-protective chemical industry reation kettle that uses

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853301A (en) * 2016-05-26 2016-08-17 彭之玉 Biological polypeptide repairing essence
CN109125201A (en) * 2017-06-19 2019-01-04 周霞 A kind of preparation method of long-acting water lock body lotion
CN107974267A (en) * 2017-11-28 2018-05-01 合肥宏润环保科技有限公司 A kind of device of food and drink greasy dirt recycling for commercial Application
CN108854911A (en) * 2018-07-17 2018-11-23 芜湖芬特勘测服务有限公司 A kind of chemical industry equipment reaction kettle
CN110448518A (en) * 2019-08-21 2019-11-15 西安博和医疗科技有限公司 A kind of preparation method of whitening body lotion
CN211754853U (en) * 2019-11-29 2020-10-27 贵州天时佳利能源开发有限责任公司 Low temperature reation kettle's heat preservation equipment
CN211800813U (en) * 2020-01-19 2020-10-30 上海福岛新材料科技有限公司 Energy-concerving and environment-protective chemical industry reation kettle that uses
CN111790337A (en) * 2020-07-09 2020-10-20 江西德盛精细化学品有限公司 Acid fixation agent produces and uses reation kettle

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张学伟: "《中国人该怎么吃》", 31 July 2016, 中医古籍出版社 *
朴香淑: "《天然活性物质在饲料中的应用研究及策略》", 30 November 2012, 中国农业大学出版社 *

Similar Documents

Publication Publication Date Title
CN105395467B (en) A kind of Chinese medicine composition, skin beautifying cosmetic and its application
KR101810231B1 (en) Cosmetic composition for improving acne containing propolis spicule powder
KR100928726B1 (en) Natural special herbal composition for the treatment of atopic skin disease and its manufacturing method
EP2345416B1 (en) Pharmaceutical composition for purifing vein and preparation method thereof
CN104922000A (en) Sunscreen repair gel and preparing method thereof
CN105380830B (en) A kind of composition and its application with anti-acne trace and suppression acne systematic function
CN105434195B (en) A kind of composition and its application with anti-acne and suppression pockmark systematic function
CN105132219A (en) Perfumed soap for smoothing striae atrophicae and preparation method thereof
CN107157835A (en) A kind of compound essential oil for preventing or repairing striae of pregnancy and preparation method thereof
CN106511211B (en) Anti-inflammatory acne-removing skin-care lotion and preparation method thereof
CN108542851A (en) A kind of Chinese medicine moisturizing anti-chapping hand cream and preparation method thereof
JP2008184416A (en) External preparation for skin, cell activation agent and antioxidation agent
CN112870302A (en) Desensitizer for effective desensitization and processing technology thereof
WO2018082117A1 (en) External traditional chinese medicine composition having function of removing red blood in skin and skin care preparation thereof
KR101966747B1 (en) Skin external composition comprising fermented extracts of antlers and preparation method thereof
WO2005065631A2 (en) Cosmetic and hygiene products containing deuterium-depleted water
RU2314093C2 (en) Curative-cosmetic agent
RU2180214C1 (en) Cream scrub
CN108078886A (en) A kind of compound Thief zone moisturizing elite and its preparation process
CN109010520A (en) A kind of ointment and preparation method thereof for treating dark sore
CN111040896A (en) Antibacterial, anti-inflammatory and skin-beautifying handmade soap
CN108403485A (en) Natural herb sunscreen
CN107157872A (en) A kind of oxidation resistant dendrobium candidum facial treatment milk of moisturizing and preparation method thereof
KR102293585B1 (en) Wax-type cleanser
KR20190050387A (en) Natural body washes using bamboo salt and manufacturing method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20210601