CN112844086B

CN112844086B - Portable injection device of sampling application of sample

Info

Publication number: CN112844086B
Application number: CN202011600668.1A
Authority: CN
Inventors: 席秋子; 邱华星
Original assignee: Suzhou Dingshi Medical Technology Co ltd
Current assignee: Suzhou Dingshi Medical Technology Co ltd
Priority date: 2020-12-29
Filing date: 2020-12-29
Publication date: 2022-05-20
Anticipated expiration: 2040-12-29
Also published as: WO2022141930A1; CN112844086A

Abstract

The invention provides a portable injection device for sampling and sample adding, which comprises a shell, a sampling device and a sampling device, wherein the shell is hollow and the top of the shell is opened to form a first cavity; a suction mechanism disposed within the first cavity; the guide part is used for guiding the reagent and is arranged at the bottom of the shell; the suction mechanism comprises a drainage piece and a gland, a hollow part is arranged in the drainage piece, the gland comprises a piston rod which is in sliding connection with the drainage piece, the piston rod extends into the hollow part of the drainage piece, so that a closed liquid mixing cavity is formed in the piston rod, and the guide part is communicated with the liquid mixing cavity, so that the carrying convenience and the operation accuracy of users are effectively improved.

Description

Portable injection device of sampling application of sample

Technical Field

The invention belongs to the field of medical instruments, and particularly relates to a portable injection device for sampling and sample adding.

Background

In the field of medical devices, particularly in fluoroimmunoassay, it is always known to use a pipette to mix a plurality of reagents into a mixed solution for analysis. However, the inventor finds that the existing sampling and loading process has at least the following problems:

firstly, in the traditional collection process, a pipetting gun is required to collect different reagents and then mix the reagents in a container, the mixed liquid is taken out and put into an analytical instrument to perform immunoassay, the collection process needs a plurality of liquids to be collected one by one, the time required by collection is longer, and the fluorescence immunoassay efficiency is limited.

In view of the above, there is a need to develop a portable injection device for sampling and injecting samples, so as to solve the above problems.

Disclosure of Invention

Aiming at the defects in the prior art, the invention mainly aims to provide a portable injection device for sampling and sample adding, which integrates the required articles for experiments, simplifies the operation steps and facilitates the use of personnel.

It is another object of the present invention to provide a portable injection device for sample application that draws a fixed amount of reagent mixture by locking the gland to limit the stretching of the mixing chamber by a fixed volume.

To achieve the above objects and other advantages in accordance with the present invention, there is provided a portable injection device for sample application, comprising:

the shell is hollow inside and the top of the shell is opened to form a first cavity;

a suction mechanism disposed within the first cavity; and

a guide portion for guiding the reagent, which is disposed at the bottom of the housing;

the suction mechanism comprises a drainage piece and a gland, a hollow part is arranged in the drainage piece, the gland comprises a piston rod which is connected with the drainage piece in a sliding mode, the piston rod extends into the hollow part of the drainage piece to enable a closed liquid mixing cavity to be formed in the hollow part of the drainage piece, and the guide part is communicated with the liquid mixing cavity.

Preferably, the drainage piece is connected with the shell in a sliding mode, and the drainage piece moves vertically along the limited direction of the first cavity under the action of external force.

Preferably, the gland further comprises a locking block, and the locking block is integrally connected with the piston rod through a cover plate;

the locking block is arranged outside the drainage piece, the shell is provided with a locking block which can be detachably connected with the locking block, and when the locking block is connected with the locking block, the gland and the shell form a relatively static fixing structure.

Preferably, the lateral wall of locking piece has seted up the locked groove, the gland can be followed the axis in muddy liquid chamber rotates, thereby makes the locked groove with the locking piece joint, thereby the restriction the gland move on the vertical direction.

Preferably, the side wall of the drainage piece is provided with a yielding groove for part of the gland to pass through.

Preferably, the abdicating groove extends downwards from the drainage piece to the middle position of the drainage piece;

the side wall of the drainage piece is also provided with a quantity limiting hole which penetrates downwards in an inclined mode, and the position of the quantity limiting hole is lower than the abdicating groove.

Preferably, the housing extends from the bottom surface toward the first cavity to form a second cavity, the bottom portion of the first cavity is recessed inwards to form a third cavity, and the second cavity and the third cavity respectively receive and absorb the guiding portions of the two reagents.

Preferably, the guide portion includes:

a straw for drawing the first liquid, mounted within the second cavity such that the straw is removably connected to the housing; and

and the second liquid cup is used for bearing a second liquid and is arranged in the third cavity.

Preferably, the drainage member comprises a drainage tube body in which the liquid mixing cavity is arranged; the drainage tube main body extends outwards to form a branch tube and a puncture part to correspond to the suction tube and the second liquid cup;

the branch pipe and the puncture part can be correspondingly connected with the suction pipe and the second liquid cup to form a liquid channel, so that the liquid is guided into the liquid mixing cavity through the liquid channel.

Compared with the prior art, the invention has the beneficial effects that:

according to the portable injection device for sampling and sample adding, different reagents are sucked into the liquid mixing cavity for mixing through the movement of the piston rod relative to the liquid mixing cavity, articles required by an experiment are integrated, the operation steps are simplified, the use of personnel is facilitated, and the portable injection device is simple in structure and convenient to use.

The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical solutions of the present invention more clearly understood and to implement them in accordance with the contents of the description, the following detailed description is given with reference to the preferred embodiments of the present invention and the accompanying drawings. The detailed description of the present invention is given in detail by the following examples and the accompanying drawings.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention without limiting the invention. In the drawings:

FIG. 1 is a cross-sectional view of a housing of the present invention in a preferred embodiment;

FIG. 2 is a schematic perspective view of a sampling device according to a preferred embodiment of the present invention;

FIG. 3 is an exploded view of a sampling device in accordance with a preferred embodiment of the present invention;

FIG. 4 is a first cross-sectional view of a sampling device in a preferred embodiment of the present invention;

FIG. 5 is a second cross-sectional view of a sampling device in a preferred embodiment of the present invention;

FIG. 6 is a perspective view of a drainage member in accordance with a preferred embodiment of the present invention;

FIG. 7 is a bottom view of the drainage member in a preferred embodiment of the invention;

FIG. 8 is a cross-sectional view of a drainage member in a preferred embodiment of the invention;

FIG. 9 is a cross-sectional view of a second liquid cup in a preferred embodiment of the invention.

Shown in the figure:

1. a drainage member;

11. a drainage tube body;

111. a liquid mixing cavity; 112. a slider; 113. a yielding groove; 114. a limiting orifice;

12. a branch pipe; 121. a first liquid channel;

13. a puncture section;

131. piercing the tip;

132. connecting ribs;

133. connecting blocks;

134. an extension block;

135. an isolation chamber;

136. a second liquid passage;

2. a housing;

21. a first cavity; 211. a chute;

23. a second cavity; 231. a bayonet;

24. a third cavity;

25. a locking block;

3. a straw;

31. a straw body; 311. a linking end; 312. a liquid inlet end;

32. buckling;

4. a second liquid cup;

41. a liquid cup body; 411. a liquid containing cavity;

42. aluminum film;

5. a gland;

51. a piston rod; 52. a locking block; 521. locking the groove; 53. and (7) a cover plate.

Detailed Description

The foregoing and other objects, features, aspects and advantages of the present invention will become more apparent to those skilled in the art from the following detailed description, which, taken in conjunction with the annexed drawings, discloses a full and partial embodiment of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

In the drawings, the shape and size may be exaggerated for clarity, and the same reference numerals will be used throughout the drawings to designate the same or similar components.

Unless defined otherwise, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention belongs. The use of "first," "second," and similar terms in the description and claims of the present application do not denote any order, quantity, or importance, but rather the terms are used to distinguish one element from another. Also, the use of the terms "a," "an," or "the" and similar referents do not denote a limitation of quantity, but rather denote the presence of at least one. The word "comprise" or "comprises", and the like, means that the element or item listed before "comprises" or "comprising" covers the element or item listed after "comprising" or "comprises" and its equivalents, and does not exclude other elements or items. "upper", "lower", "left", "right", and the like are used merely to indicate relative positional relationships, and when the absolute position of the object being described is changed, the relative positional relationships may also be changed accordingly.

In the following description, terms such as center, thickness, height, length, front, back, rear, left, right, top, bottom, upper, lower, and the like are used based on the orientation or positional relationship shown in the drawings. In particular, "height" corresponds to the dimension from top to bottom, "width" corresponds to the dimension from left to right, and "depth" corresponds to the dimension from front to back. These relative terms are for convenience of description and are not generally intended to require a particular orientation. Terms concerning attachments, coupling and the like (e.g., "connected" and "attached") refer to a relationship wherein structures are secured or attached, either directly or indirectly, to one another through intervening structures, as well as both movable or rigid attachments or relationships, unless expressly described otherwise.

The present invention will be further described with reference to the accompanying drawings and the detailed description, and it should be noted that any combination of the embodiments or technical features described below can be used to form a new embodiment without conflict.

According to the technical solution of the present invention, as shown with reference to fig. 1 and 2, a portable injection device for sampling and sample-adding comprises a housing 2 for forming a coating structure of the sampling device; wherein the housing 2 is hollow inside and open at its top end to form a first cavity 21;

referring to fig. 5, the housing 2 extends from the bottom surface toward the first cavity 21 to form a second cavity 23, and a bottom portion of the first cavity 21 is recessed to form a third cavity 24;

the second cavity 23 and the third cavity 24 are used for receiving a guide part of a diversion reagent; in a preferred embodiment, the guide portion sucks the first liquid and the second liquid respectively;

in particular, the second cavity 23 is used for connecting a pipette 3 in the sampling device for sucking the first liquid; the third cavity 24 is used for receiving a second liquid cup 4 in the sampling device, and second liquid is contained in the second liquid cup 4;

the pumping mechanism is arranged in the first cavity 21, a plurality of reagents are conveniently sucked into the pumping mechanism for mixing at the same time, liquid is pressed into the closed space by the pumping mechanism in a mode of increasing the volume of the closed space in the pumping mechanism and reducing the pressure, different reagents are conveniently sucked into the liquid mixing cavity for mixing, articles required by an experiment are integrated, the operation steps are simplified, and the use personnel are facilitated.

In a preferred embodiment, the suction mechanism comprises: a drainage member 1 disposed within the first cavity 21; the housing 2 is reserved with a containing space for receiving the drainage piece 1, the suction pipe 3 and the second liquid cup 4, so that the sampling device is integrated conveniently and is portable, and the situation that the sampling device is inconvenient to carry outdoors or in special scenes is solved; and the number of the first and second groups,

the gland 5 comprises a piston rod 51, and the piston rod 51 is connected with the drainage member 1 in a sliding way;

the drainage member 1 comprises a drainage tube body 11, the interior of the drainage tube body is hollow, the piston rod 51 extends into the hollow part of the drainage tube body 11 to form a closed liquid mixing cavity 111, and the volume of the liquid mixing cavity 111 is changed by relative sliding between the gland 5 and the drainage member 1, so that a reagent is sucked into the liquid mixing cavity 111;

the gland 5 further comprises a locking block 52, and the locking block 52 is integrally connected with the piston rod 51 through a cover plate 53;

the locking block 52 is arranged outside the drainage member 1, the housing 2 is provided with a locking block 25 which can be detachably connected with the locking block 52, when the locking block 52 is connected with the locking block 25, the gland 5 and the housing 2 form a relatively static fixed structure, as can be seen in the figure, the locking block 52 is arranged outside the housing 2, and the locking block 25 is correspondingly arranged on the outer side wall of the housing 2, however, it should be understood that the arrangement position of the locking block 52 is fixed, in the present invention, the locking block 52 and the locking block 25 form a locking structure, at this time, when the drainage member 1 is pressed down by external force, the gland 5 moves relative to the drainage member 1, the liquid mixing cavity 111 is stretched to cause the volume increase, so that the reagent is sucked into the liquid mixing cavity 111, since the pressing down movement of the drainage member 1 is limited by the housing 2, make the tensile volume increase value of drainage piece 1 certain, consequently, the reagent volume of inhaling in mixing the liquid chamber 111 is certain, because this injection device is used for carrying out the analysis, consequently, the volume of single suction reagent need not too big, avoids causing the waste, through lock piece 52 and lock piece 25 form the locking structure, have restricted effectively that mixing the liquid chamber 111 inhales the reagent volume to satisfy quantitative requirement.

Specifically, the gland 5 and the housing 2 form a relatively stationary fixed structure, so that the gland 5 and the liquid mixing cavity 111 in the housing 2 form a fixed stroke for limiting the drainage member 1, so that the drainage member 1 moves in one end stroke of the limited stroke, the stretching space of the liquid mixing cavity 111 is controlled, the amount of the reagent sucked into the liquid mixing cavity 111 is controlled, and the quantification is achieved.

The side wall of the locking block 52 is provided with a locking groove 521, the gland 5 can rotate along the axis of the liquid mixing cavity 111, so that the locking groove 521 is clamped with the locking block 25 to limit the gland 5 to move in the vertical direction, and the locking or unlocking is realized by rotating the locking block 52, so that sampling or sample adding is controlled.

Offer on the lateral wall of drainage piece 1 and supply the part the groove 113 of stepping down that gland 5 passed, as above, because reagent sample and application of sample volume do not need very big, consequently, mix the volume of liquid chamber 111 and do not need very big, nevertheless owing to need suction liquid, make piston rod 51's design requirement is longer to the length increase that has led to the fact whole injection device, through setting up the groove 113 of stepping down for the length of piston rod 51 has been shortened, has reduced the length of whole device, makes it more conveniently carry.

Further, as shown in fig. 8, the relief groove 113 extends downward from the drainage member 1 to a middle position of the drainage member 1; the side wall of the drainage member 1 is further provided with a limiting hole 114 which penetrates obliquely downwards, the position of the limiting hole 11 is lower than the abdicating groove 113, when the piston rod 51 slides to the position of the limiting hole 11, the liquid mixing cavity 111 is not in a closed state any more, and the reagent cannot be sucked into the liquid mixing cavity 111, so that the amount of the reagent in the liquid mixing cavity 111 is limited, the maximum amount of the reagent in the liquid mixing cavity 111 is limited, and meanwhile, the inclined limiting hole 114 limits the liquid from overflowing from the limiting hole 114 through the inclined inner side wall.

A branch pipe 12 provided at the bottom of the draft tube body 11; and

a puncturing part 13 located on the same side of the drain tube body 11 near the branch tube 12;

the branch pipe 12 is provided with a first liquid channel 121 from the bottom thereof and extends into the liquid mixing cavity 111, and the first liquid is sucked into the liquid mixing cavity 111 through the branch pipe 12;

the puncture part 13 is provided with a second liquid channel 136 from the bottom thereof and extends into the liquid mixing cavity 111, and the bottom of the puncture part 13 is provided with a protruding block which extends downwards to form a puncture sharp head 131 for puncturing an aluminum film;

specifically, referring to fig. 3 and 4, the drainage member 1 is driven by an external force, so that the drainage member 1 moves to the branch pipe 12 to be connected with the suction pipe 3, meanwhile, the puncturing part 13 extends into the second liquid cup 4, so that the branch pipe 12 and the suction pipe 3 form a liquid channel of the first liquid, a liquid channel of the second liquid is formed in the puncturing part 13, and finally, the two liquids enter the liquid mixing cavity 111 to be mixed.

Referring to fig. 9, the puncturing part 13 punctures the aluminum film 42 covering the second liquid cup 4, the second liquid cup 4 is hollow to form a liquid containing cavity 411 for containing the second liquid, the liquid containing cavity 411 forms an opening at the top of the second liquid cup 4, when the connecting block 133 extends into the liquid containing cavity 411 from the opening, the opening is hermetically connected with the outer edge of the connecting block 133, and when continuous pressing and space limitation occur, the second liquid in the liquid containing cavity 411 is pressed into the liquid mixing cavity 111 from the second liquid channel 136.

The second liquid and the first liquid are mixed in the liquid mixing cavity 111 at the same time to form a solution required to be used for fluorescence immunoassay, and the puncture part 13 is integrated on the drainage piece 1, so that the problem that a pipetting gun and a pipetting gun head need to be carried at the same time is solved, and the carrying convenience is improved; meanwhile, the puncturing part 13 and the branch pipe 12 can simultaneously collect two liquids and mix the two liquids in the liquid mixing cavity 111, so that the operation steps are simplified, and the analysis efficiency is improved.

The suction pipe 3 is detachably connected with the shell 2; specifically, a bayonet 231 is formed in the inner wall of the second cavity 23, the bayonet 231 corresponds to a buckle 32 arranged on the outer wall of the straw 3, the buckle 32 is arranged at one end of the straw 3 close to a joint end 311, the joint end 311 extends into the first cavity 21 and is hermetically connected with the branch pipe 12, and a liquid inlet end 312 at the other end of the straw 3 extends into a first liquid container for containing a first liquid to suck the first liquid.

The bayonet 231 is disposed on the inner walls of the two sides corresponding to the second cavity 23 and penetrates the outer side of the housing 2, and the suction pipe 3 is disconnected from the housing 2 by pushing the snap 32 from the through hole of the outer side of the housing 2.

A sliding groove 211 extending along the vertical direction is formed in the inner side wall of the first cavity 21, and a sliding block 112 corresponding to the sliding groove 211 is arranged on the outer wall of the drainage tube main body 11; the drainage piece 1 is limited by the sliding groove 211 to slide in a direction so as to reciprocate along the vertical direction; furthermore, an annular raised skirt is arranged on the outer edge of the shell 2 to provide a force application point for an operator, so that the drainage piece 1 can be conveniently driven to move relative to the shell.

As shown in fig. 6 and 7, the puncturing part 13 includes a connecting block 133, the extending direction of the connecting block 133 is parallel to the extending direction of the branch pipe 12, when the drainage member 1 is driven, the puncturing part 13 and the branch pipe 12 can move in the same direction to facilitate both to simultaneously extend into two containers containing different liquids, so as to suck the two liquids for mixing;

an extension block 134 is integrally connected to the top of the connection block 133, the extension block 134 is extended and combined to the side wall of the drainage tube body 11, and the connection block 133 and the extension block 134 are combined to form the main structure of the puncturing part 13.

The second liquid channel 136 in the connecting block 133 passes through the connecting block 133 up and down to form a hollow portion and is communicated to the second liquid channel 136 in the extending block 134;

connecting ribs 132 distributed radially are arranged in the hollow part of the connecting block 133, so that a plurality of isolation cavities 135 are formed between the connecting ribs 132 and the hollow inner wall of the connecting block 133, and the isolation cavities 135 are communicated with the second liquid channel 136 in the extending block 134.

The connecting ribs 132 are intersected to form a central column located in the axial direction of the connecting block 133, the puncturing pointed end 131 is arranged on the central column, the aluminum film 42 is punctured by the puncturing pointed end 131 at the central position, the aluminum film 42 is uniformly punctured by the puncturing part 13, the situation that the strutting state is affected by overlong local aluminum film 42 is avoided, or a part of the aluminum film 42 extends into the second liquid when the part of the aluminum film 42 is overlong to pollute the liquid, so that the mixed solution fails.

The piercing pointed end 131 is circular, the piercing pointed end 131 is the same in shape and size or larger than the cross section of the central column, so that the piercing pointed end 131 and the connecting rib 132 directly form a whole, after the piercing pointed end 131 pierces the aluminum film 42, the joint of the piercing pointed end 131 and the connecting rib 132 is pressed on the aluminum film 42, the aluminum film 42 is easily opened due to high pressure, the piercing pointed end 131 and the central column are prevented from forming a step-shaped structure, when the piercing pointed end 131 pierces the aluminum film 42, the central column is in contact with the aluminum film 42, and the central column is difficult to be separated from the aluminum film 42 due to the fact that the contact area is increased and the pressure is reduced.

In a preferred embodiment, the opening is shaped and sized to conform to the outer edge of the connecting piece 133, and the connecting piece 133 extends into the opening to form a sealed connection.

In another preferred embodiment, the opening is smaller than the outer edge of the connecting block 133; the liquid cup body 41 of the second liquid cup 4 is made of silica gel, when the connecting block 133 extends into the liquid containing cavity 411, the connecting block 133 props open the opening elastically, and the liquid cup body 41 has certain elasticity and variability so that the opening is tightly wrapped on the connecting block 133, and the sealing performance is better.

Referring to fig. 4, the bottom of the liquid containing cavity 411 is tapered, the connecting rib 132 extends outwards from the bottom of the connecting block 133, the shape of the extending connecting rib 132 corresponds to the shape of the bottom of the liquid containing cavity 411, the contact area of the extending connecting rib 132 and the aluminum film 42 is reduced, and the pressure is increased so that the connecting rib 132 can prop open the aluminum film 42.

The number of the connecting ribs 132 is three, the connecting ribs 132 divide the hollow space in the connecting block 133 to form three isolating cavities 135, the isolating cavities 135 are respectively communicated with the second liquid channel 136 in the extending block 134, and the aluminum film 42 is separated and isolated by the connecting ribs 132 so as to ensure that the second liquid cup 4 is normally pressed into the second liquid channel 136.

The method for sampling and sample adding by adopting the portable injection device in the preferred embodiment specifically comprises the following steps: the gland 5 and the drainage piece 1 are adjusted to be in a closed state, at the moment, one end of the piston rod 51 extending into the drainage piece 1 is in contact with the bottom of the hollow part in the drainage piece 1, and the volume of the liquid mixing cavity 111 can be regarded as zero;

the gland 5 is rotated to lock the locking block 52 and the locking block 25, the drainage member 1 is pressed, at the moment, the drainage member 1 is pressed to move, the branch pipe 12 is connected with the suction pipe 3 to form a liquid suction channel of the first liquid, meanwhile, the puncture part 13 punctures the aluminum film 42 on the second liquid cup 4 and extends into the liquid containing cavity 411, and because the volume of the liquid mixing cavity 111 is gradually increased, the first liquid and the second liquid are simultaneously sucked into the liquid mixing cavity 111 to be mixed;

when the piston rod 51 crosses the limiting hole 114, the liquid in the liquid mixing cavity 111 is kept unchanged, at this time, the pressing cover 5 is rotated reversely to unlock the lock block 52 and the lock block 25, the pressing cover 5 is pushed to press the piston rod 51 into the liquid mixing cavity 111, so that the mixed liquid is pressed out from the branch pipe 12, and the puncturing part 13 is still positioned in the liquid containing cavity 411, so that the mixed liquid is difficult to overflow from the puncturing part 13, and therefore, the mixed liquid is quantitatively pressed out from the branch pipe 12, and thus, the quantitative sample adding is realized.

The foregoing is merely a preferred embodiment of this invention and is not intended to limit the invention in any manner; those skilled in the art can readily practice the invention as shown and described in the drawings and detailed description herein; however, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the scope of the invention as defined by the appended claims; meanwhile, any changes, modifications, and evolutions of the equivalent changes of the above embodiments according to the actual techniques of the present invention are still within the protection scope of the technical solution of the present invention.

Claims

1. A portable injection device for sample application, comprising:

a housing (2) which is hollow inside and has an open top to form a first cavity (21);

a suction mechanism arranged within the first cavity (21); and

a guide for guiding the reagent, which is arranged at the bottom of the housing (2);

the suction mechanism comprises a drainage piece (1) and a gland (5), a hollow part is arranged in the drainage piece (1), the gland (5) comprises a piston rod (51) which is in sliding connection with the drainage piece (1), the piston rod (51) extends into the hollow part of the drainage piece (1) so that a closed liquid mixing cavity (111) is formed in the piston rod (51), and the guide part is communicated with the liquid mixing cavity (111);

the shell (2) extends from the bottom surface to the first cavity (21) to form a second cavity (23), the bottom part of the first cavity (21) is sunken inwards to form a third cavity (24), and the second cavity (23) and the third cavity (24) respectively receive guide parts for sucking two reagents;

the drainage piece (1) is connected with the shell (2) in a sliding mode, and the drainage piece (1) moves vertically along the direction limited by the first cavity (21) under the action of external force;

the gland (5) further comprises a locking block (52), and the locking block (52) is integrally connected with the piston rod (51) through a cover plate (53);

the locking block (52) is arranged outside the drainage piece (1), the shell (2) is provided with a locking block (25) which can be detachably connected with the locking block (52), and when the locking block (52) is connected with the locking block (25), the gland (5) and the shell (2) form a relatively static fixed structure;

the guide portion includes:

a suction tube (3) for sucking a first liquid, mounted in the second cavity (23) so that the suction tube (3) is detachably connected to the housing (2); and

a second liquid cup (4) for receiving a second liquid, said second liquid cup being received in said third cavity (24);

the drainage piece (1) comprises a drainage tube main body (11) internally provided with the liquid mixing cavity (111); the drainage tube main body (11) extends outwards to form a branch tube (12) and a puncture part (13) to correspond to the suction tube (3) and the second liquid cup (4);

the branch pipe (12) and the puncture part (13) can be correspondingly connected with the suction pipe (3) and the second liquid cup (4) to form a liquid channel, so that the liquid is guided into the liquid mixing cavity (111) through the liquid channel.

2. The portable injection device according to claim 1, wherein a locking groove (521) is formed on a side wall of the locking block (52), and the gland (5) can rotate along an axis of the liquid mixing chamber (111), so that the locking groove (521) is clamped with the locking block (25), and the gland (5) is limited to move in a vertical direction.

3. The portable injection device according to claim 2, wherein the drainage member (1) has a sidewall formed with a relief groove (113) for a portion of the gland (5) to pass through.

4. A portable injection device according to claim 3, wherein the relief groove (113) extends from the drain (1) down to a central position of the drain (1);

the side wall of the drainage piece (1) is also provided with a limiting hole (114) which penetrates downwards in an inclined mode, and the position of the limiting hole (114) is lower than the yielding groove (113).