CN112841362A

CN112841362A - Liver-protecting tea bag and preparation method and application thereof

Info

Publication number: CN112841362A
Application number: CN202110091150.8A
Authority: CN
Inventors: 梁俊雄
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-01-22
Filing date: 2021-01-22
Publication date: 2021-05-28

Abstract

The invention discloses a liver-protecting tea bag, which consists of cassia seed, giant knotweed, hawthorn and penthorum chinense pursh. The weight parts of the components are as follows: 1-30 parts of cassia seed, 1-30 parts of giant knotweed, 1-30 parts of hawthorn and 1-25 parts of penthorum chinense pursh; more preferably, the weight parts of the components are as follows: 5-25 parts of cassia seed, 5-25 parts of giant knotweed, 5-25 parts of hawthorn and 3-20 parts of penthorum chinense pursh; further preferably, the weight parts of the components are as follows: 10-20 parts of cassia seed, 10-20 parts of giant knotweed, 10-20 parts of hawthorn and 5-15 parts of penthorum chinense pursh. The invention also discloses a preparation method of the liver protection tea bag and application of the liver protection tea bag in the aspects of dispelling effects of alcohol and protecting liver.

Description

Liver-protecting tea bag and preparation method and application thereof

Technical Field

The invention relates to the field of food, in particular to a liver protection tea bag, a preparation method thereof and application of the liver protection tea bag in the aspects of dispelling effects of alcohol and protecting liver.

Background

At present, the types of alcohol-relieving products on the market are various, however, most products are very troublesome to use, liver injury can be caused by acute excessive drinking or alcoholism caused by long-term drinking, fatty liver, liver cirrhosis and liver cancer can be formed in long time, and the products are common clinical lethal factors. Therefore, daily food for relieving alcoholism and protecting liver is urgently needed, and the tea bag has the advantages of convenience in carrying, easiness in brewing, time saving and trouble saving. The inventor organically combines the two to successfully manufacture the liver protection tea bag which can obviously improve the life quality of people.

Disclosure of Invention

The invention discloses a liver-protecting tea bag, which consists of cassia seed, giant knotweed, hawthorn and penthorum chinense pursh.

A liver-protecting tea bag comprises the following components in parts by weight: 1-30 parts of cassia seed, 1-30 parts of giant knotweed, 1-30 parts of hawthorn and 1-25 parts of penthorum chinense pursh; more preferably, the weight parts of the components are as follows: 5-25 parts of cassia seed, 5-25 parts of giant knotweed, 5-25 parts of hawthorn and 3-20 parts of penthorum chinense pursh; further preferably, the weight parts of the components are as follows: 10-20 parts of cassia seed, 10-20 parts of giant knotweed, 10-20 parts of hawthorn and 5-15 parts of penthorum chinense pursh.

The invention also discloses a preparation method of the liver-protecting tea bag, which specifically comprises the following steps: the method comprises the steps of drying, crushing, sterilizing, granulating and packaging. Specifically, the method comprises respectively drying four tea bag raw materials (semen Cassiae, rhizoma Polygoni Cuspidati, fructus crataegi, herba Penthori chinensis) to water content of 10-15%; a crushing step: respectively crushing the four dried tea bag raw materials; and (3) sterilization: sterilizing the crushed tea bag raw materials; a granulation step: mixing the four products obtained in the sterilization step, and granulating; packaging: and (4) putting the product obtained in the granulating step into a tea bag packaging machine for packaging to obtain the liver-protecting tea bag.

The invention also discloses another preparation method of the liver-protecting tea bag, which specifically comprises the following steps: the method comprises the steps of drying, crushing, extracting and concentrating, sterilizing, granulating and packaging. Specifically, the method comprises respectively drying four tea bag raw materials (semen Cassiae, rhizoma Polygoni Cuspidati, fructus crataegi, herba Penthori chinensis) to water content of 10-15%; a crushing step: respectively crushing the four dried tea bag raw materials; an extraction and concentration step: respectively carrying out water extraction and alcohol precipitation operations commonly used in the industry on the four tea bag raw materials, and carrying out spray drying on alcohol precipitation components to obtain semi-finished products; and (3) sterilization: sterilizing the semi-finished product obtained in the step of extracting and concentrating; a granulation step: mixing the four products obtained in the sterilization step, and granulating; packaging: and (4) putting the product obtained in the granulating step into a tea bag packaging machine for packaging to obtain the liver-protecting tea bag.

Further, in some embodiments of the present invention, after the pulverizing step and before the sterilizing step, the above manufacturing method further comprises: a screening step; the screening step comprises: sieving the crushed tea bag raw materials by using a mesh screen, and taking the sieved materials; the particle size of the raw materials is adjusted by adjusting the mesh number of the screen, generally, the screened substance with the mesh size of 15-30 is used as the raw materials for subsequent processing, so that the packaging and the leaching of water-soluble substances are facilitated, the unique flavor is maintained, and the effects of dispelling the effects of alcohol and protecting the liver are achieved.

The liver protection tea bag is applied to the aspects of dispelling the effects of alcohol and protecting the liver.

The combination of the components in the liver-protecting tea bag raw material can play a synergistic role. In particular, the method of manufacturing a semiconductor device,

semen Cassiae has sweet and bitter taste, cold nature and slight salty taste, and has effects of removing liver fire, improving eyesight, and loosening bowel to relieve constipation.

Giant knotweed rhizome has the functions of promoting blood circulation, dissipating blood stasis, dredging meridian, relieving cough, etc.

The hawthorn is sour and sweet in nature and slightly warm in nature, has the effects of reducing blood fat and blood pressure, strengthening heart, resisting arrhythmia and the like, and is also a good medicine for tonifying spleen, stimulating appetite, promoting digestion, removing food stagnation, promoting blood circulation and reducing phlegm, and has the effects of inducing diuresis, reducing swelling, clearing liver and benefiting gallbladder.

Penthorum chinense Pursh, sweet in nature and taste, warm in nature, has the effects of promoting diuresis, removing dampness, removing blood stasis and relieving pain, and is commonly used for relieving liver injury.

The above components are absent. Compared with the traditional tea bag, the liver protection tea bag has the obvious functions of dispelling the effects of alcohol and protecting the liver.

Detailed Description

Example 1:

drying semen Cassiae 15g, rhizoma Polygoni Cuspidati 15g, fructus crataegi 15g, and herba Penthori chinensis 10g, pulverizing, sterilizing by conventional method, and packaging into teabag.

Example 2:

drying semen Cassiae 20g, rhizoma Polygoni Cuspidati 18g, fructus crataegi 18g, and herba Penthori chinensis 12g, pulverizing, filtering with 20 mesh sieve, sterilizing by conventional method, and packaging into teabag.

Comparative example 1:

20.625g of semen Cassiae, 20.625g of hawthorn and 13.75g of penthorum chinense pursh, drying and crushing the raw materials, then sterilizing by a general method, and packaging into tea bags.

In order to verify the effect of the liver protection tea bag on relieving alcoholism and protecting liver, the following research is carried out.

Liver-protecting tea bag has effects of preventing and alleviating hangover of alcohol-induced mice

1 Material

1.1 animals: SPF-grade Kunming mice, male, weighing 20g + -2 g.

1.2 drugs and reagents: the liver protection tea bag prepared in example 1 is brewed with boiled water and cooled to room temperature; a comparative tea, prepared in comparative example 1, brewed in boiled water and cooled to room temperature; 56 ° distilled spirit, beijing red star gmbh; physiological saline.

2 methods and results

After 120 Kunming mice were acclimatized for one week, they were randomly assigned: blank, model, experimental and control groups 4, 30 of each. After the mice are fasted and not inhibited from water for 12 hours, the experiment group and the comparison group are respectively administered with the liver protection tea bag in the example 1 and the tea bag in the comparison example 1 for intragastric administration, the dosage is 800mg/kg, the blank group and the model group are administered with equal volume of physiological saline, and the intragastric administration volume is 20 ml/kg. After 30 minutes, the stomach was perfused with 56 ° distilled spirit 14ml/kg except for the blank group. And recording the time of the disappearance and recovery of the righting reflex after the mice are drunk, and calculating the drunk time and the sober-up time of each group of mice. The drunk time is the time from the pouring of the mouse to the disappearance of the righting reflex, and the sober-up time is the time from the disappearance of the righting reflex to the recovery of the righting reflex. The results are shown in Table 1.

TABLE 1 influence of liver-protecting teabag on drunkenness time and sober-up time of alcoholic intoxication mice (x + -s, n ═ 30)

P < 0.05 compared to model group.

The results show that compared with the model group, the experimental group can prolong the drunkenness time of the mice and shorten the sobering-up time, and has very significant difference P less than 0.05.

Compared with the control group, the experimental group can prolong the drunkenness time of the mice and shorten the sobering-up time, and has very significant difference P less than 0.05.

Second, protection effect of liver protection tea bag on liver of mouse with alcoholic liver injury

1 Material

1.1 animals: SPF-grade Kunming mice, male, weighing 20g + -2 g.

1.2 drugs and reagents: the liver protection tea bag prepared in example 1 is brewed with boiled water and cooled to room temperature; a comparative tea, prepared in comparative example 1, brewed in boiled water and cooled to room temperature; 56 ° distilled spirit, beijing red star gmbh; physiological saline; alanine Aminotransferase (ALT) and aspartate Aminotransferase (AST) detection kit, Nanjing, to build the bioengineering institute.

2 methods and results

After 40 Kunming mice were acclimatized for one week, they were randomly assigned: blank group, model group, experimental group, comparative group 4, each group 10. The blank group is not subjected to intragastric administration, the model group is given physiological saline with the same volume, the experimental group and the comparison group are respectively given the liver protection tea bag in the example 1 and the tea bag in the comparative example 1 for intragastric administration, the dosage is 800mg/kg, and the intragastric administration volume is 20 ml/kg. After 30 minutes of administration by intragastric administration every day, the mice were intragastric administered with 16ml/kg of 56-degree white spirit except for the blank group. Continuously performing gavage for 10 days, fasting without water after the gavage for 10 days, weighing after 24 hours, and collecting serum and liver for relevant detection. ALT and AST are measured by a colorimetric method according to the kit specification, and the concentration of ALT and AST is an important index for detecting liver injury. The results are shown in tables 2 and 3.

Table 2 influence of liver-protecting tea bag on alcoholic liver injury mice (x ± s, n ═ 10)

P < 0.05, P < 0.01, P < 0.001, compared to model group.

The results show that the liver quality of the model group is obviously higher than that of the blank group, the experimental group and the comparison group, the liver weight ratio is the highest in the model group, and the liver weight ratio is the lowest in the experimental group and the comparison group. Compared with the model group and the comparison group, the experimental group can effectively reduce the elevation of ALT and AST and has protective effect on the liver injury of mice.

The technical solutions provided by the embodiments of the present invention are described in detail above, and the principles and embodiments of the present invention are explained herein by using specific examples, and the descriptions of the embodiments are only used to help understanding the principles of the embodiments of the present invention; meanwhile, for a person skilled in the art, according to the embodiments of the present invention, there may be variations in the specific implementation manners and application ranges, and in summary, the content of the present description should not be construed as a limitation to the present invention.

Claims

1. A liver-protecting teabag is characterized by comprising cassia seed, giant knotweed rhizome, hawthorn fruit and penthorum chinense pursh.

2. The liver-protecting teabag according to claim 1, wherein the weight parts of each component are as follows: 1-30 parts of cassia seed, 1-30 parts of giant knotweed, 1-30 parts of hawthorn and 1-25 parts of penthorum chinense pursh.

3. The liver-protecting teabag according to claim 2, wherein the weight parts of each component are as follows: 5-25 parts of cassia seed, 5-25 parts of giant knotweed, 5-25 parts of hawthorn and 3-20 parts of penthorum chinense pursh.

4. The liver-protecting teabag according to claim 3, wherein the weight parts of each component are as follows: 10-20 parts of cassia seed, 10-20 parts of giant knotweed, 10-20 parts of hawthorn and 5-15 parts of penthorum chinense pursh.

5. The method for preparing liver-protecting teabag according to any one of claims 1-4, wherein: comprises the steps of drying, crushing, sterilizing, granulating and packaging; the liver protecting teabag is prepared from semen Cassiae, rhizoma Polygoni Cuspidati, fructus crataegi, and herba Penthori chinensis.

6. The method for preparing liver-protecting teabag according to claim 5, wherein the method comprises the following steps: comprises the steps of drying, crushing, extracting, concentrating, sterilizing, granulating and packaging; the liver protecting teabag is prepared from semen Cassiae, rhizoma Polygoni Cuspidati, fructus crataegi, and herba Penthori chinensis.

7. The liver-protecting teabag according to any one of claims 1-4 for relieving alcoholism and protecting liver.