CN112807544A - Acousto-optic intelligent control system for auxiliary treatment of Alzheimer's disease and implementation device - Google Patents

Acousto-optic intelligent control system for auxiliary treatment of Alzheimer's disease and implementation device Download PDF

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Publication number
CN112807544A
CN112807544A CN202110187825.9A CN202110187825A CN112807544A CN 112807544 A CN112807544 A CN 112807544A CN 202110187825 A CN202110187825 A CN 202110187825A CN 112807544 A CN112807544 A CN 112807544A
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Prior art keywords
module
stimulation
frame
light
sound
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CN202110187825.9A
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Chinese (zh)
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桂赟
张旭
毛旭瑞
陈弘达
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Suzhou Leahuier Technology Co ltd
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Jiangsu Jicui Brain Machine Integration Intelligent Technology Research Institute Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Acoustics & Sound (AREA)
  • Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
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  • Radiation-Therapy Devices (AREA)

Abstract

The invention discloses an acousto-optic intelligent control system for adjuvant therapy of Alzheimer's disease, which comprises: the stimulation module comprises a sound stimulation module and a light stimulation module, the sound stimulation module is used for generating stimulation audio, and the light stimulation module is used for generating stimulation light; the power supply module is connected with the stimulation module and used for supplying power; and the control module is connected with the stimulation module and the power supply module and is at least used for controlling and adjusting the sound stimulation module to generate sound in a specific frequency range and controlling and adjusting the light stimulation module to generate stimulation light with a specific flicker frequency. The invention also provides an implementation device for assisting in treating the Alzheimer's disease. The invention has the advantages that the shape of the glasses is common glasses, the glasses can be used at any time in any occasion, the user is not influenced by the external attention, and the glasses have the function of assisting in treating AD.

Description

Acousto-optic intelligent control system for auxiliary treatment of Alzheimer's disease and implementation device
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to an acousto-optic intelligent control system for assisting in treating Alzheimer's disease and an implementation device.
Background
Alzheimer's Disease (AD) is a degenerative disease of the nervous system, and is clinically manifested as learning and memory disorder, cognitive impairment, language disorder and the like, which seriously affects the daily life of patients and increases the nursing cost of families. In recent years, with the gradual increase of social aging, tens of millions to hundreds of millions of old people face the risk of suffering from AD all over the world, and the aging society is further challenged.
The existing main treatment modes for treating AD on the market are drug treatment modes, but the drug treatment can only relieve the symptoms of AD and cannot cure AD, and meanwhile, the drugs can bring side effects such as nausea, headache, diarrhea, hallucinations and the like to patients. The other modes of non-drug therapy mainly use large medical equipment such as acousto-optic electromagnetic equipment to clinically treat AD patients in hospitals, and cannot be used in a portable mode in daily life.
In the activity of the brain, neuron groups participate in rhythmic synchronization in a gamma frequency band of 30-90 Hz, and gamma concussion is related to a large number of high-order cognitive functions. Animal experiments show that 40Hz flickering light irradiation and 40Hz sound stimulation can effectively reduce the beta amyloid level in the CA1 region of the hippocampus of AD-suffering mice and induce the change of states of microglia, and the beta amyloid level is a main biochemical index of Alzheimer's disease, so that experimental results show that 40Hz flickering light irradiation and 40Hz sound stimulation can improve the Alzheimer's disease condition, and the method is a potential effective method for preventing and treating AD.
Therefore, in order to solve the above technical problems, it is necessary to provide an intelligent acousto-optic control system and an implementation device for assisting in the treatment of alzheimer's disease.
Disclosure of Invention
The invention aims to provide an acousto-optic intelligent control system for assisting in treating Alzheimer's disease and an implementation device.
In order to achieve the above object, an embodiment of the present invention provides the following technical solutions:
in one embodiment, an acousto-optic intelligent control system for assisting in treating alzheimer disease is provided, which includes:
the stimulation module comprises a sound stimulation module and a light stimulation module, the sound stimulation module is used for generating stimulation audio, and the light stimulation module is used for generating stimulation light;
the power supply module is connected with the stimulation module and used for supplying power;
and the control module is connected with the stimulation module and the power supply module and is at least used for controlling and adjusting the sound stimulation module to generate sound in a specific frequency range and controlling and adjusting the light stimulation module to generate stimulation light with a specific flicker frequency.
As a further improvement of the invention, the system also comprises an input module, wherein the input module is connected with the control module and at least used for adjusting the required audio volume and the light brightness.
As a further improvement of the present invention, the control module includes a bluetooth communication unit and a battery management unit, the bluetooth communication unit is used for implementing bluetooth signal transmission with an external terminal, and the battery management unit implements charge and discharge control of the battery module.
As a further improvement of the invention, the system also comprises an acquisition module, wherein the acquisition module is connected with the control module and is used for acquiring voice signals, converting the received voice signals into audio data and outputting the audio data to an external terminal through a Bluetooth communication unit.
In one embodiment, an implementation device for assisting in treating alzheimer disease is provided, and the implementation device is provided with the acousto-optic intelligent control system.
As a further improvement of the present invention, the implementation device includes a frame and a frame connected to the frame, the battery module and the control module are disposed in the frame, the frame is provided with a charging interface, and the charging interface is connected to the battery module.
As a further improvement of the present invention, the spectacle frame is provided with a bent portion of a suspension loop, the sound stimulation module includes a speaker, and the speaker is disposed on the bent portion of the suspension loop.
As a further improvement of the present invention, the light stimulation module includes LED lamps, and the LED lamps are disposed on both sides of the frame near the frame.
As a further improvement of the present invention, the input module includes a key structure, the key structure is configured on the mirror bracket, and the key structure can be used to implement the on/off, sound volume adjustment, and LED lamp brightness adjustment of the intelligent acousto-optic control system.
As a further improvement of the invention, the spectacle frame comprises a metal framework and soft silica gel coated outside the metal framework.
Compared with the prior art, the invention has the advantages that:
the invention integrates sound stimulation and light stimulation into the same system, and controls the system through the control module to realize single specific frequency audio frequency stimulation or single specific flicker frequency light stimulation or acousto-optic simultaneous stimulation, thereby achieving the effect of preventing and treating AD.
The invention integrates the acousto-optic stimulation into an implementation device as a novel treatment method, has no side effect caused by drug treatment, and also achieves the effects of preventing and relieving AD.
The invention has the appearance of common glasses, can be used at any time in any occasion, does not bring external attention to influence users, and can be used as presbyopic glasses and Bluetooth earphones to meet the daily life use when the auxiliary treatment function is not used.
The implementation device of the invention is an innovative device which can meet the daily life requirements and the requirements of prevention and auxiliary treatment of AD diseases.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments described in the present application, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a block diagram of an acousto-optic intelligent control system for the adjuvant therapy of Alzheimer's disease according to an embodiment of the present application;
FIG. 2 is a diagram of an apparatus for assisting in the treatment of Alzheimer's disease, in accordance with an embodiment of the present application;
fig. 3 is a flowchart of the operation of the acousto-optic intelligent control system for the adjuvant therapy of alzheimer's disease in an embodiment of the present application.
Detailed Description
The present invention will be described in detail below with reference to embodiments shown in the drawings. The embodiments are not intended to limit the present invention, and structural, methodological, or functional changes made by those skilled in the art according to the embodiments are included in the scope of the present invention.
Referring to fig. 1, in an embodiment of the present application, an intelligent acousto-optic control system for assisting in treating alzheimer's disease is provided, which includes a control module 1, a battery module 2, a sound stimulation module 3, a light stimulation module 4, an input module 5, and a collection module 6.
The control module 1 adopts a master control chip Bluetooth audio SoC, the master control SoC comprises a Bluetooth communication unit, a power management unit and a master control MCU unit, the Bluetooth communication unit is used for realizing Bluetooth signal transmission with an external terminal, and the battery management unit is connected with the battery module 2 to realize the charge and discharge control and management of the battery module 2.
The sound stimulation module 3 is connected with the control module 1 and the battery module 2, comprises a plurality of loudspeakers and a power amplifier acting on the loudspeakers, can generate sound in a specific frequency range under the action of the control module 1, and is used for generating stimulation audio for a user; and generating voice prompting the working state of the system.
The light stimulation module 4 is connected with the control module 1 and the battery module 2, comprises a plurality of LED lamps, can generate light with a specific flicker frequency under the action of the control module 1 and is used for generating stimulation light for a user; and the LED lamp can also be used for prompting the working state of the system.
The input module 5 is connected with the control module 1 and the battery module 2 and comprises a plurality of key structures, and the key structures are used for inputting system startup and shutdown, audio volume adjustment, LED lamp stimulation brightness adjustment and the like.
The acquisition module 6 is connected with the control module 1 and comprises a microphone for acquiring voice signals, converting the received voice signals into audio data and outputting the audio data to an external terminal through a Bluetooth communication unit to serve as a voice call function.
In the acousto-optic intelligent control system, two functional modes are set, wherein one mode is an AD prevention mode, and the other mode is a common mode;
when the mobile phone is in the AD prevention mode, the control module 1 transmits audio with a preset specific frequency range, which is arranged in an APP (external terminal) of the smart phone, through the Bluetooth communication unit, and plays the stimulation audio through a loudspeaker to realize a sound stimulation function for a user; and/or the control module 1 controls the LED lamp of the light stimulation module 4 to flash at the frequency of 40Hz, so that the light stimulation function of the user is realized, and the Alzheimer disease is treated in an auxiliary manner. The brightness of the LED lamp can be adjusted through the key structure and APP adjustment; the stimulation audio signals can be used for selecting different stimulation audio modes and volume adjustment through an APP in the smart phone, and can also be used for mode selection and volume adjustment through a key structure.
Because the frequency range of sound which can be received by the auditory system of human is 16 Hz-20 KHz, the auditory system is insensitive to sound with lower frequency below 100Hz, and the effect of directly using the audio signal of 40Hz as the sound stimulation signal is not good; meanwhile, the old people are easy to have high-frequency hearing loss due to hearing degradation, so that the system uses a signal lower than 8KHz as a carrier frequency, and uses a 40Hz signal as a modulation frequency in an amplitude modulation or frequency modulation mode to generate a required stimulation audio signal.
When being in the normal mode, control module 1 control light stimulation module 4 closes the LED lamp, and control module 1 passes through the bluetooth communication unit and connects smart mobile phone (external terminal), plays the cell-phone audio frequency through the speaker, reaches the effect of bluetooth headset, uses as daily life.
Referring to fig. 2, in an embodiment, an implementation device for assisting in treating alzheimer's disease is further provided, and the implementation device is configured as a pair of common glasses 10, and the glasses are provided with the above-mentioned acousto-optic intelligent control system; the normal eyeglasses 10 include a frame 11, lenses 12 provided in the frame, and a frame 13 connected to the frame, and the lenses may be configured as presbyopic lenses so as to be suitable for the daily life and use of the elderly.
The control module 1 and the battery module 2 are arranged in the spectacle frames 13 positioned at the left side and the right side of the ordinary spectacles 10, and in order to ensure the portability of the device, the battery module 2 adopts a rechargeable lithium battery for power supply, and meanwhile, the interference of power frequency signals is avoided; the mirror bracket 13 is provided with a type-C charging interface which is connected with a rechargeable lithium battery; the design is compact, the total weight is less than 150g, and the daily use comfort level of the old can be met; simultaneously, this implementation device is in order to satisfy different people's the demand of wearing, and mirror holder 13 uses soft silica gel and metal skeleton design, and size is adjustable and satisfy the comfort level demand when can making different people wear.
The LED lamps 14 for light stimulation are mounted on the inner sides, close to the spectacle frame 13, of the two sides of the spectacle frame 11 of the ordinary spectacles 10, the spectacle frame 13 is provided with a plurality of key structures, and the key structures are connected with the control module 1 and used for turning on and off, adjusting the volume of a loudspeaker, adjusting the brightness of the LED lamps and selecting functional modes so as to avoid discomfort of a user.
The frame 11 is provided with a bent portion of a suspension loop, and a speaker 15 for sound stimulation is disposed at the bent portion of the suspension loop of the frame 13.
When the device is used for key operation, the device is provided with key prompt tones, so that the device is convenient for old people to use.
This implementation device except that selecting through the button structure on the mirror holder 11 and setting up, can also use the APP of smart mobile phone installation configuration development, can select to play amazing audio through the APP to and set for treatment time length every day.
Referring to fig. 3, the present embodiment includes the following 2 operation modes: AD prevention mode, normal mode.
Under prevention AD mode, through button structure switch on the glasses or through the last auxiliary treatment APP of smart mobile phone switch 4 kinds of treatment modes: 40Hz sound stimulation alone, 40Hz light stimulation alone, simultaneous sound and light stimulation, and prevention of AD mode shutdown.
The length of use per day can be seen in APP, and according to prior experiments, the time of use per day of the acousto-optic stimulus does not exceed 1 hour. When the control module detects that the AD preventative mode is used for more than one hour, the functional mode will be turned off until it can be re-enabled after 24 hours.
Under the ordinary mode, this implementation device uses as ordinary bluetooth headset and presbyopic glasses.
Compared with the prior art, the invention has the advantages that:
the invention integrates sound stimulation and light stimulation into the same system, and controls the system through the control module to realize single specific frequency audio frequency stimulation or single specific flicker frequency light stimulation or acousto-optic simultaneous stimulation, thereby achieving the effect of preventing and treating AD.
The invention integrates the acousto-optic stimulation into an implementation device as a novel treatment method, has no side effect caused by drug treatment, and also achieves the effects of preventing and relieving AD.
The invention has the appearance of common glasses, can be used at any time in any occasion, does not bring external attention to influence users, and can be used as presbyopic glasses and Bluetooth earphones to meet the daily life use when the auxiliary treatment function is not used.
The implementation device of the invention is an innovative device which can meet the daily life requirements and the requirements of prevention and auxiliary treatment of AD diseases.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (10)

1. An acousto-optic intelligent control system for assisting in treating Alzheimer's disease, which is characterized by comprising:
the stimulation module comprises a sound stimulation module and a light stimulation module, the sound stimulation module is used for generating stimulation audio, and the light stimulation module is used for generating stimulation light;
the power supply module is connected with the stimulation module and used for supplying power;
and the control module is connected with the stimulation module and the power supply module and is at least used for controlling and adjusting the sound stimulation module to generate sound in a specific frequency range and controlling and adjusting the light stimulation module to generate stimulation light with a specific flicker frequency.
2. The intelligent acousto-optic control system for assisting in the treatment of alzheimer's disease according to claim 1, further comprising an input module, wherein the input module is connected to the control module and at least used for adjusting the required audio volume and the brightness of the light.
3. The system according to claim 1, wherein the control module comprises a bluetooth communication unit and a battery management unit, the bluetooth communication unit is used for transmitting bluetooth signals with an external terminal, and the battery management unit is used for controlling charging and discharging of the battery module.
4. The intelligent acousto-optic control system for assisting in treating alzheimer's disease according to claim 3, further comprising an acquisition module, wherein the acquisition module is connected to the control module and is used for acquiring voice signals, converting the received voice signals into audio data and outputting the audio data to an external terminal through the bluetooth communication unit.
5. An implementation device for assisting in treating alzheimer's disease, wherein the implementation device is equipped with the acousto-optic intelligent control system according to any one of claims 1-4.
6. The device according to claim 5, wherein the device comprises a frame and a frame connected to the frame, the battery module and the control module are disposed in the frame, the frame has a charging interface, and the charging interface is connected to the battery module.
7. The device of claim 6, wherein the frame has an ear bend, and the sound stimulation module comprises a speaker, the speaker being disposed on the ear bend.
8. The device as claimed in claim 6, wherein the light stimulation module comprises LED lamps disposed on both sides of the frame adjacent to the frame.
9. The device as claimed in claim 6, wherein the input module comprises a key structure, the key structure is disposed on the frame, and the key structure is used to implement turning on and off, sound volume adjustment, and LED light brightness adjustment of the intelligent acousto-optic control system.
10. The device as claimed in claim 6, wherein the frame comprises a metal frame and a soft silicone covering the metal frame.
CN202110187825.9A 2021-02-18 2021-02-18 Acousto-optic intelligent control system for auxiliary treatment of Alzheimer's disease and implementation device Pending CN112807544A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115192852A (en) * 2022-07-13 2022-10-18 军事科学院军事医学研究院环境医学与作业医学研究所 Brain wave adjusting device based on acousto-optic stimulation
EP4169498A1 (en) * 2021-10-25 2023-04-26 Bottneuro AG Method for generating stimulation-audio-files

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4169498A1 (en) * 2021-10-25 2023-04-26 Bottneuro AG Method for generating stimulation-audio-files
WO2023072839A1 (en) * 2021-10-25 2023-05-04 Bottneuro Ag Method for generating stimulation-audio-files
CN115192852A (en) * 2022-07-13 2022-10-18 军事科学院军事医学研究院环境医学与作业医学研究所 Brain wave adjusting device based on acousto-optic stimulation

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