CN112773866A - Ointment formula for adjuvant treatment of pulmonary tuberculosis and bronchitis and preparation method thereof - Google Patents

Ointment formula for adjuvant treatment of pulmonary tuberculosis and bronchitis and preparation method thereof Download PDF

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CN112773866A
CN112773866A CN202110032674.XA CN202110032674A CN112773866A CN 112773866 A CN112773866 A CN 112773866A CN 202110032674 A CN202110032674 A CN 202110032674A CN 112773866 A CN112773866 A CN 112773866A
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朱月恒
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
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    • A61K2236/10—Preparation or pretreatment of starting material
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention discloses a paste formula for adjuvant therapy of phthisis and bronchitis, which comprises American ginseng, radix rehmanniae, walnut, wolfberry fruit, chinaroot greenbrier rhizome, bletilla striata and white honey, wherein the weight ratio of the American ginseng in the formula is 2.1%, the weight ratio of the radix rehmanniae in the formula is 21.3%, the weight ratio of the walnut in the formula is 7.1%, the weight ratio of the wolfberry fruit in the formula is 7.1%, the weight ratio of the chinaroot greenbrier rhizome in the formula is 7.1%, the weight ratio of the bletilla striata in the formula is 5.7%, and the weight ratio of the white honey in the formula is 49.6%; the preparation has the effects of supplementing qi, nourishing yin and filling the essence, can be used for effectively assisting in treating tuberculosis, bronchitis and alopecia caused by internal strain and seven injury, and has the characteristics of unique preparation, complex preparation, convenient administration, good effect, quick response, obvious curative effect and obvious rehabilitation effect compared with the prior art.

Description

Ointment formula for adjuvant treatment of pulmonary tuberculosis and bronchitis and preparation method thereof
Technical Field
The invention relates to the technical field of ointment, in particular to an ointment formula for adjuvant therapy of pulmonary tuberculosis and bronchitis and a preparation method thereof.
Background
Tuberculosis, bronchitis and alopecia are common diseases in the traditional Chinese medicine internal medicine. The former two symptoms are chronic cough, little phlegm, dry throat and mouth or blood-stained phlegm, dyspnea with movement, sometimes light and heavy day and night, and aggravation by wind-cold, even emphysema, pulmonary heart disease and the like. The latter is manifested as irregular head loss, commonly known as "ghost shaving head", or hair loss in women with high childbirth and abortion. All three persistent ailments belong to chronic nutritional wasting diseases. For example, cold is not well treated for a long time, the body function resistance caused by the deficiency of defensive yang is poor, and patients with repeated cold, chronic tumor and diabetes can all suffer from the disease.
Tuberculosis, bronchitis and alopecia belong to the categories of 'five-strain seven-impairment' and 'essence-blood deficiency' in traditional Chinese medicine, and the traditional Chinese medicine considers that the main reasons for the three diseases are liver-kidney yin deficiency and deficiency-fire burning on the lung, which is the delicate organ and is most vulnerable to injury. When lung is injured, body fluid cannot be infused, body fluid is easy to fall off due to phlegm and hair being scorched, and clinically, the treatment of pulmonary tuberculosis, bronchitis and alopecia is mainly treated by methods of tonifying qi and yin, nourishing yin and lung, and replenishing essence and supplementing marrow.
At present, western medicines are mostly adopted for symptomatic treatment of pulmonary tuberculosis and bronchitis. For example: tuberculosis is treated by antituberculosis drugs and antibiotics; bronchitis is treated with aminophylline and antibiotics; alopecia is treated with blood-tonifying medicine. These drugs are effective in the early stage of treatment of the above diseases, and have many drugs, no obvious or even no effect, and great side effects. The long-term hospitalization consumes time, money and physical strength, and the hope of thorough cure is still not met.
Disclosure of Invention
The invention aims to provide a paste formula for adjuvant therapy of pulmonary tuberculosis and bronchitis and a preparation method thereof, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
the paste formula for adjuvant therapy of phthisis and bronchitis comprises American ginseng, radix rehmanniae, walnut, wolfberry fruit, chinaroot greenbrier rhizome, bletilla striata and white honey, wherein the weight ratio of the American ginseng in the formula is 2.1%, the weight ratio of the radix rehmanniae in the formula is 21.3%, the weight ratio of the walnut in the formula is 7.1%, the weight ratio of the wolfberry fruit in the formula is 7.1%, the weight ratio of the chinaroot greenbrier rhizome in the formula is 7.1%, the weight ratio of the bletilla striata in the formula is 5.7%, and the weight ratio of the white honey in the formula is 49.6%.
A preparation method of a paste formula for adjuvant therapy of pulmonary tuberculosis and bronchitis comprises the following steps:
step 1, removing impurities adhered to the surfaces of the American ginseng, the rehmannia root, the walnut, the wolfberry fruit, the white poria and the bletilla striata by dry cleaning;
step 2, exposing the American ginseng, the radix rehmanniae, the walnut, the white poria and the bletilla striata to be dry and crisp, and simultaneously freezing the wolfberry to be hard and crisp;
step 3, respectively feeding the crisp and hard medicines obtained in the step 2 into a pulverizer to be processed into powder;
step 4, uniformly stirring the various medicinal powders obtained in the step 3 to obtain uniformly stirred mixed medicinal powder;
step 5, guiding the uniformly mixed medicinal powder into a crock, simultaneously injecting white honey into the crock, and stirring until the mixed paste is in a maltose shape;
step 6, sealing the opening of the stirred tile tank through the straw paper and the gauze;
step 7, taking a big-end pot, adding a certain amount of water into the big-end pot, and then placing the closed crock in the big-end pot and locating at the center of the big-end pot;
step 8, closing the big-end pot, then heating the big-end pot to ensure that the temperature in the pot is between 100 and 110 ℃, and continuously steaming and decocting the big-end pot for 72 hours;
step 9, opening the big-end pot, taking out the pot after the temperature of the pot is reduced, opening the pot, measuring the viscosity of the paste, and determining that the viscosity is 1.3-1.4 at the temperature of 60 ℃ to be qualified;
and step 10, subpackaging the qualified paste into sterile glass bottles, and performing sterile packaging.
In the step 2, the medicine which is exposed to the sun to be crisp is sliced, and the sliced medicine is placed in a baking oven and baked at the temperature of 40-50 ℃ until the body is fat.
The medlar in the step 2 needs to be frozen until the water in the medlar is crystallized, and the medlar can be processed into powder.
The filling volume of the tile pot in the step 5 is 60 to 65 percent.
In the step 6, the number of the layers of the straw paper is not less than ten to twelve, and the gauze is positioned above the straw paper.
Compared with the prior art, the invention has the beneficial effects that: the preparation has the effects of supplementing qi, nourishing yin and filling the essence, can be used for effectively assisting in treating tuberculosis, bronchitis and alopecia caused by internal strain and seven injury, and has the characteristics of unique preparation, complex preparation, convenient administration, good effect, quick response, obvious curative effect and obvious rehabilitation effect compared with the prior art.
Detailed Description
The technical solutions will be described clearly and completely in the following with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Examples
The invention provides a technical scheme that: the paste formula for adjuvant therapy of phthisis and bronchitis comprises American ginseng, radix rehmanniae, walnut, wolfberry fruit, chinaroot greenbrier rhizome, bletilla striata and white honey, wherein the weight ratio of the American ginseng in the formula is 2.1%, the weight ratio of the radix rehmanniae in the formula is 21.3%, the weight ratio of the walnut in the formula is 7.1%, the weight ratio of the wolfberry fruit in the formula is 7.1%, the weight ratio of the chinaroot greenbrier rhizome in the formula is 7.1%, the weight ratio of the bletilla striata in the formula is 5.7%, and the weight ratio of the white honey in the formula is 49.6%.
A preparation method of a paste formula for adjuvant therapy of pulmonary tuberculosis and bronchitis comprises the following steps:
step 1, removing impurities adhered to the surfaces of the American ginseng, the rehmannia root, the walnut, the wolfberry fruit, the white poria and the bletilla striata by dry cleaning;
step 2, exposing the American ginseng, the radix rehmanniae, the walnut, the white poria and the bletilla striata to be dry and crisp, and simultaneously freezing the wolfberry to be hard and crisp;
step 3, respectively feeding the crisp and hard medicines obtained in the step 2 into a pulverizer to be processed into powder;
step 4, uniformly stirring the various medicinal powders obtained in the step 3 to obtain uniformly stirred mixed medicinal powder;
step 5, guiding the uniformly mixed medicinal powder into a crock, simultaneously injecting white honey into the crock, and stirring until the mixed paste is in a maltose shape;
step 6, sealing the opening of the stirred tile tank through the straw paper and the gauze;
step 7, taking a big-end pot, adding a certain amount of water into the big-end pot, and then placing the closed crock in the big-end pot and locating at the center of the big-end pot;
step 8, closing the big-end pot, then heating the big-end pot to ensure that the temperature in the pot is between 100 and 110 ℃, and continuously steaming and decocting the big-end pot for 72 hours;
step 9, opening the big-end pot, taking out the pot after the temperature of the pot is reduced, opening the pot, measuring the viscosity of the paste, and determining that the viscosity is 1.3-1.4 at the temperature of 60 ℃ to be qualified;
and step 10, subpackaging the qualified paste into sterile glass bottles, and performing sterile packaging.
In the step 2, the medicine which is exposed to the sun to be crisp is sliced, and the sliced medicine is placed in a baking oven and baked at the temperature of 40-50 ℃ until the body is fat.
The medlar in the step 2 needs to be frozen until the water in the medlar is crystallized, and the medlar can be processed into powder.
The filling volume of the tile pot in the step 5 is 60 to 65 percent.
In the step 6, the number of the layers of the straw paper is not less than ten to twelve, and the gauze is positioned above the straw paper.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. The ointment formula for adjuvant therapy of pulmonary tuberculosis and bronchitis is characterized in that: the cream formula comprises American ginseng, radix rehmanniae, walnut, medlar, chinaroot greenbrier rhizome, bletilla striata and white honey, wherein the weight ratio of the American ginseng in the formula is 2.1%, the weight ratio of the radix rehmanniae in the formula is 21.3%, the weight ratio of the walnut in the formula is 7.1%, the weight ratio of the medlar in the formula is 7.1%, the weight ratio of the white poria in the formula is 7.1%, the weight ratio of the bletilla striata in the formula is 5.7%, and the weight ratio of the white honey in the formula is 49.6%.
2. The preparation method of the paste formula for the adjuvant therapy of pulmonary tuberculosis and bronchitis according to claim 1, is characterized in that: the method comprises the following steps:
step 1, removing impurities adhered to the surfaces of the American ginseng, the rehmannia root, the walnut, the wolfberry fruit, the white poria and the bletilla striata by dry cleaning;
step 2, exposing the American ginseng, the radix rehmanniae, the walnut, the white poria and the bletilla striata to be dry and crisp, and simultaneously freezing the wolfberry to be hard and crisp;
step 3, respectively feeding the crisp and hard medicines obtained in the step 2 into a pulverizer to be processed into powder;
step 4, uniformly stirring the various medicinal powders obtained in the step 3 to obtain uniformly stirred mixed medicinal powder;
step 5, guiding the uniformly mixed medicinal powder into a crock, simultaneously injecting white honey into the crock, and stirring until the mixed paste is in a maltose shape;
step 6, sealing the opening of the stirred tile tank through the straw paper and the gauze;
step 7, taking a big-end pot, adding a certain amount of water into the big-end pot, and then placing the closed crock in the big-end pot and locating at the center of the big-end pot;
step 8, closing the big-end pot, then heating the big-end pot to ensure that the temperature in the pot is between 100 and 110 ℃, and continuously steaming and decocting the big-end pot for 72 hours;
step 9, opening the big-end pot, taking out the pot after the temperature of the pot is reduced, opening the pot, measuring the viscosity of the paste, and determining that the viscosity is 1.3-1.4 at the temperature of 60 ℃ to be qualified;
and step 10, subpackaging the qualified paste into sterile glass bottles, and performing sterile packaging.
3. The preparation method of the paste formula for the adjuvant therapy of pulmonary tuberculosis and bronchitis according to claim 2, is characterized in that: in the step 2, the medicine which is exposed to the sun to be crisp is sliced, and the sliced medicine is placed in a baking oven and baked at the temperature of 40-50 ℃ until the body is fat.
4. The preparation method of the paste formula for the adjuvant therapy of pulmonary tuberculosis and bronchitis according to claim 2, is characterized in that: the medlar in the step 2 needs to be frozen until the water in the medlar is crystallized, and the medlar can be processed into powder.
5. The preparation method of the paste formula for the adjuvant therapy of pulmonary tuberculosis and bronchitis according to claim 2, is characterized in that: the filling volume of the tile pot in the step 5 is 60 to 65 percent.
6. The preparation method of the paste formula for the adjuvant therapy of pulmonary tuberculosis and bronchitis according to claim 2, is characterized in that: in the step 6, the number of the layers of the straw paper is not less than ten to twelve, and the gauze is positioned above the straw paper.
CN202110032674.XA 2021-01-08 2021-01-08 Ointment formula for adjuvant treatment of pulmonary tuberculosis and bronchitis and preparation method thereof Pending CN112773866A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105963526A (en) * 2016-05-31 2016-09-28 朱月恒 Traditional Chinese medicine ointment assisting in treating tuberculosis, bronchitis and hair loss

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105963526A (en) * 2016-05-31 2016-09-28 朱月恒 Traditional Chinese medicine ointment assisting in treating tuberculosis, bronchitis and hair loss

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