CN112772723A - Formula of milk powder beneficial to development of immune system of children and production method thereof - Google Patents

Formula of milk powder beneficial to development of immune system of children and production method thereof Download PDF

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CN112772723A
CN112772723A CN202110020226.8A CN202110020226A CN112772723A CN 112772723 A CN112772723 A CN 112772723A CN 202110020226 A CN202110020226 A CN 202110020226A CN 112772723 A CN112772723 A CN 112772723A
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milk
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许哲峰
白春利
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Shanghai Yingbeikang Maternal And Infant Products Co ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/158—Milk preparations; Milk powder or milk powder preparations containing additives containing vitamins or antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1522—Inorganic additives, e.g. minerals, trace elements; Chlorination or fluoridation of milk; Organic salts or complexes of metals other than natrium or kalium; Calcium enrichment of milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1526—Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/156—Flavoured milk preparations ; Addition of fruits, vegetables, sugars, sugar alcohols or sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
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    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/21—Streptococcus, lactococcus
    • A23V2400/231—Lactis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/51—Bifidobacterium
    • A23V2400/531—Lactis

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Abstract

The invention relates to a milk powder formula beneficial to development of immune systems of children, which comprises cow/goat milk, whey powder, lactose, cow colostrum powder, vegetable oil, fructo-oligosaccharide, galacto-oligosaccharide, docosahexaenoic acid grease, L-carnitine, lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics, choline, magnesium, calcium, iron, zinc, selenium, vitamin A, vitamin D, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, nicotinic acid, folic acid, pantothenic acid and biotin.

Description

Formula of milk powder beneficial to development of immune system of children and production method thereof
Technical Field
The invention relates to the field of modified milk powder, in particular to a formula of milk powder beneficial to development of an immune system of children and a production method thereof, and particularly relates to a formula of modified milk powder suitable for 3-year-old children, aiming at improving the immunity of the children or improving the development of the immune system of the children.
Background
The immune system is the most fundamental and effective mechanism for the human body to resist the invasion of external bacteria, viruses and harmful substances and to eliminate the self-produced harmful substances in the body. For children, the immune system is not mature, the prime phase of development of the immune system of children is before 16 years old, and besides sleeping and moving, sufficient nutrition supplement is very important.
The dairy product is rich in high-quality protein, vitamins and minerals such as calcium, iron, zinc and the like for children over 3 years old, and is a very ideal nutritional supplement. The dairy product supplement of 300 plus 400ml per day for preschool children and the dairy product supplement of 300ml per day for school-age children are recommended in the book "Chinese resident meal index finger south 2016" compiled by the Chinese Nutrition society.
At present, the dairy products on the market are various and can be roughly divided into liquid milk such as pure milk, yoghourt, children milk and the like and milk powder dairy products such as whole milk powder, children milk powder and the like. The liquid milk and the children milk powder in the market are relatively low in nutrition added additionally, and particularly at present, the children are difficult to meet the nutritional requirements of the children due to the fact that the phenomenon of monophagia of the children is increasingly serious. And less dairy products with strong pertinence and help immune system development, and the market needs more accurate and more targeted child dairy products with more nutrient addition. However, due to national regulations, the nutrient types of liquid milk are allowed to be added in a limited way, the nutrient addition range of the children milk powder is wider, and the children milk powder with high pertinence and accurate nutrition is a development direction in the future.
Human immunity is the most effective way to combat unknown diseases. In children, due to immaturity of the immune system and lack of knowledge about hygiene and disease, the ability to fight disease is weaker than in adults, the ability to fight unknown disease is worse, the immune system is enhanced, resistance is provided, and the most urgent need is for children.
Disclosure of Invention
The invention relates to a formula of milk powder beneficial to development of immune systems of children, which comprises cow/goat milk, whey powder, lactose, cow colostrum powder, vegetable oil, fructo-oligosaccharide, galacto-oligosaccharide, docosahexaenoic acid grease, L-carnitine, lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics, choline, magnesium, calcium, iron, zinc, selenium, vitamin A, vitamin D, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, nicotinic acid, folic acid, pantothenic acid and biotin.
Preferably, the bovine colostrum powder is added in an amount of 1-10 g per 100g of milk powder.
Preferably, the addition amount of the N-acetylneuraminic acid is 10-50mg/100g of milk powder.
Preferably, the addition amount of the yeast beta-glucan is 30-100mg/100g milk powder.
Preferably, the probiotic bacteria are bifidobacterium lactis, lactobacillus rhamnosus, and lactobacillus lactis subsp.
Preferably, 10 hundred million CFU of Bifidobacterium lactis, 10 hundred CFU of Lactobacillus rhamnosus and 10 hundred million CFU of lactococcus lactis subspecies lactis are added to every 100g of milk powder.
The nutrient content of the milk powder is as follows:
Figure BDA0002888256920000021
Figure BDA0002888256920000031
in another aspect, the invention relates to a method for producing a milk powder formula which is beneficial to the development of the immune system of children, comprising the following steps:
1) adding liquid milk: according to the formula requirement, introducing a specified amount of purified raw cow/goat milk or whole fat/skimmed milk into a milk storage tank 1; if the formula does not use liquid milk, adding treated purified water;
2) redissolving and treating the main materials: adding the pretreated purified water into the blending tank 1, adding solid raw materials such as whole milk powder, skimmed milk powder, whey powder, lactose and the like according to the formula requirement, stirring to completely dissolve, and introducing into the milk storage tank 1;
3) adding vegetable oil: adding vegetable oil into a milk storage tank 1 according to the formula requirement;
4) dissolving dietary fiber: adding fructo-oligosaccharide and galacto-oligosaccharide into the blending tank 2 according to the formula requirement, stirring to dissolve completely, and introducing into the milk storage tank 1;
5) dissolving the vitamins: adding vitamin A, vitamin D, vitamin C, vitamin K1, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotinic acid, folic acid, pantothenic acid, biotin, choline and L-carnitine into a dissolving tank 2 according to the formula requirements, stirring to completely dissolve, and then introducing into a milk storage tank 1;
6) dissolving minerals: adding calcium, magnesium, iron, zinc and selenium into the dissolving tank 2 according to the formula requirements, stirring to completely dissolve, and then introducing into the milk storage tank 1;
7) and (3) sterilization: sterilizing the mixed solution through a pipeline at the temperature of 121-135 ℃;
8) homogenizing: homogenizing the sterilized milk liquid under 10-14 Mpa;
9) concentrating and drying: firstly, carrying out reduced pressure concentration, wherein the vacuum degree is 46-87Kpa, and the concentration is 15-27-degree Ba; the air inlet temperature is 165-190 ℃ and the air outlet temperature is 68-94 ℃, so that the biological activity and the nutrient content of most of proteins in the production process of the formula milk powder are ensured; finally, fluidized bed drying is carried out, the air inlet temperature is 35-95 ℃, and the fluidization speed is 0.05-3.5 m/s;
10) adding other raw materials: uniformly mixing lactoferrin, bovine colostrum powder, N-acetylneuraminic acid, yeast beta-glucan, probiotics and DHA with the semi-finished milk powder according to the formula requirement in a ratio of 1:10, adding a dry mixer, and stirring for 20-40 min;
11) packaging: filling the stirred finished product powder in a clean workshop;
the bovine colostrum powder can be added in step 10); the bovine colostrum powder, N-acetylneuraminic acid, yeast beta-glucan and DHA can also be added in step 5).
Alternatively, a method for producing a milk powder formula beneficial to the development of the immune system of children comprises the following steps:
1) unpacking: removing external package of raw materials such as customized vegetable fat powder (vegetable oil, whey powder), whole milk powder, skimmed milk powder, etc., and placing the internal package into a workshop for temporarily storing raw materials in a cleaning area by air showering and ultraviolet sterilization;
2) weighing small materials: according to the formula requirements, weighing and subpackaging vitamins, mineral substances, L-carnitine, choline, fructo-oligosaccharide, galacto-oligosaccharide, bovine colostrum powder, lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics and DHA small materials, sterilizing the surfaces of packages, and then sending the packages into a mixing workshop for later use;
3) mixing small materials 1: uniformly mixing lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics and DHA with the semi-finished milk powder according to the proportion of 1:10 respectively;
4) mixing small materials 2: uniformly mixing fructo-oligosaccharide, galacto-oligosaccharide and semi-finished product according to the ratio of 1: 10;
5) mixing raw materials: adding vitamin A, vitamin D, vitamin C, vitamin K1, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotinic acid, folic acid, pantothenic acid, biotin, choline, L-carnitine, calcium, magnesium, iron, zinc and selenium, the mixed powder obtained in the step 3) and the bovine colostrum powder into the semi-finished milk powder according to the formula requirements, adding a dry mixing machine, and stirring for 20-40 min;
6) packaging: and filling the stirred finished product powder in a clean workshop.
Advantageous effects
The human immune system can be divided into specific immunity (acquired immunity) and non-specific immunity (innate immunity)
Specific immunity:
specific immunity is an acquired defense function gradually established after birth of a human body, and is characterized in that the specific immunity is generated after birth and only acts on a specific pathogen or foreign matter, so the specific immunity is called as specific immunity and acquired immunity.
The specific immunity mainly comprises immune organs (thymus, lymph nodes, spleen and the like) and immune cells (lymphocytes), and comprises humoral immunity of B lymphocyte mediated conductors and T lymphocyte mediated cellular immunity;
b cells, also called B lymphocytes, are cells capable of producing antibodies against each particular invader or antigen. When a B cell is contacted with an antigen, it rapidly divides more B cells and releases antibodies that lock tightly against the invader, prevent the invader from entering human cells and producing toxins, and recruit immune legionella T cells.
T cells, also called T lymphocytes, can be classified as helper T lymphocytes, suppressor T lymphocytes and NK lymphocytes (natural killer cells), which can produce cytotoxins to destroy invaders. Helper T lymphocytes can help activate B cells, enhancing their sensitivity to invaders; when the immune system wins, the T lymphocyte can be inhibited to turn off the immune reaction, so as to avoid the over-excitation of the immune reaction and the loss of the self cell.
Non-specific immunity:
the natural defense function of non-specific immune human body is gradually established in the course of evolution, and is characterized by that it is not aimed at a specific pathogen, and has the defense effect for several pathogens. Including skin and mucous membranes, bactericidal substances, phagocytic cells, etc.
Skin and mucous membrane include external skin and internal mucous membrane of digestive tract, respiratory tract and other mucous membrane tissues, which not only can prevent pathogens from invading human body, but also their secretions (such as lactic acid, fatty acid, gastric acid and enzyme, etc.) have bactericidal effect. Cilia are formed on the respiratory mucosa to remove foreign matters.
The bactericidal substance and phagocyte include bactericidal substances such as lactoferrin and lysozyme in body fluid and intestinal tract, and immunocyte such as phagocyte, killer cell and dendritic cell.
Macrophages are phagocytic cells that engulf and digest invaders that have been recognized by B and T cells, thereby completely ending the immune war.
In most cases, nonspecific immunity prevents the invasion of pathogens into the body.
The invention relates to a milk powder formula beneficial to helping the development of an immune system of children and a production method of a related technology.
1. Specific immunity
1) Sufficient B vitamins and zinc and selenium are added.
The rapid generation of B cells and T cells, and the development of normal immunity, are not separated from B vitamins and zinc and selenium. Especially, vitamin B6, folic acid and zinc can help the generation of immune cells, the generation of antibodies can not be separated from vitamin B6, and the lack of other B vitamins can inhibit the immune function.
The formula of the vitamin B complex can meet the requirement of more than 60% of B vitamins such as vitamin B6, folic acid and the like required by Chinese children every day, and particularly, the most easily lacked vitamin B2 and vitamin B12 can reach 80% of the daily required amount of the children. The zinc can basically meet the daily basic requirements of Chinese children.
2) Yeast beta-glucan was added.
The yeast beta-glucan can stimulate and enhance the phagocytic activity of immune cells such as NK lymphocytes and macrophages, enhance the capability of killing harmful substances, stimulate T cells to proliferate to generate more NK lymphocytes and stimulate B cells to generate more antibodies.
3) Adding bovine colostrum powder.
Bovine colostrum powder contains a large number of immunologically active substances, including active substances such as immunoglobulin G (antibody), lysozyme, nucleotides, etc. The immune substances can inhibit and kill harmful bacteria and viruses.
4) 3 kinds of probiotics are added.
About 70% of human immune cells are located in the intestinal tract, and probiotics in the intestinal tract can stimulate functional maturation of the immune cells to play a role of a trainer. The combination of multiple species of probiotics can enhance a wider variety of immune cells. The accuracy and the high efficiency of the specific immunity of the immune cells are improved.
The probiotics can quickly proliferate in intestinal tract to form dominant bacteria, inhibit proliferation of harmful bacteria in intestinal tract by survival competition, reduce disease treatment probability of harmful bacteria, and play a role in nonspecific immunity
5) 2 prebiotics (fructo-oligosaccharides + galacto-oligosaccharides) were added.
The prebiotics can not be absorbed by human body, but can be absorbed and utilized by the probiotics, so that more food is provided for the probiotics, the probiotics are helped to quickly proliferate, and the dominant bacteria are formed. And the prebiotics form acidic substances after being utilized by the probiotics, and inhibit the proliferation of harmful bacteria.
2. Specific immunity
1) Adding N-acetylneuraminic acid.
The virus invades human mucosal cells by the specific combination of the marker protein on the surface of the virus and the N-acetylneuraminic acid on the marker protein on the surface of the mucosal cells, so that the virus invades the cells. The virus surface identification protein is a key, the mucosal cell surface identification protein is a door, the N-acetylneuraminic acid on the mucosal cell surface identification protein is a lock, and the virus can enter the mucosal cell by opening the door by opening the N-acetylneuraminic acid lock. The method is characterized in that free N-acetylneuraminic acid is added to be combined with identification protein (key) of the virus in advance, so that the virus cannot be combined with human mucosal cells, the mucosa is protected, invasion of the virus is reduced, immunity is enhanced, and resistance is improved.
2) Vitamin A, vitamin C and zinc are sufficient.
Vitamin A and vitamin C can maintain skin elasticity, reduce skin injury, maintain skin and mucosa integrity and health, and prevent invasion of harmful substances such as bacteria and virus.
Most harmful bacteria generate free radicals, and destroy skin and mucosa barriers through strong oxidation of the free radicals, so that the harmful bacteria invade the human body. Vitamin A, vitamin C, zinc, etc. are antioxidants, can effectively remove free radicals, and protect the health of skin and mucosa.
3) Lactoferrin was added.
Lactoferrin can bind iron element, thereby reducing the absorption of iron, an essential element, by bacteria and affecting the growth of harmful bacteria. And can be used for resisting various viruses such as I type and II type herpes simplex virus, cytomegalovirus, human immunodeficiency virus, hepatitis C virus, hantavirus, rotavirus, I type poliomyelitis virus, human respiratory syncytial virus, murine leukemia virus, etc.
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FIG. 1 is a method of producing a milk powder for promoting the development of the immune system of a child according to an embodiment of the present invention;
FIG. 2 is a method for preparing milk powder to promote the development of the immune system of children in another embodiment of the present invention.
Detailed Description
The invention relates to milk powder beneficial to development of immune systems of children, a specific preparation method of the milk powder can adopt a dry-wet compounding method process, a flow schematic diagram is shown in figure 1, and the milk powder comprises the following steps:
1) adding liquid milk: according to the formula requirements, a specified amount of purified raw cow/goat milk or whole fat/skim milk is introduced into a milk storage tank 1 (if liquid milk is not used in the formula, purified water is added).
2) Redissolving and treating the main materials: adding the pretreated purified water into the blending tank 1, adding the solid raw materials such as whole milk powder, skimmed milk powder, whey powder, lactose and the like according to the formula requirement, stirring to completely dissolve, and introducing into the milk storage tank 1. (bovine colostrum powder can be added in step 10)
3) Adding vegetable oil: according to the formula requirements, vegetable oil is added into the milk storage tank 1.
4) Dissolving dietary fiber: adding fructo-oligosaccharide and galacto-oligosaccharide into the blending tank 2 according to the formula requirement, stirring to dissolve completely, and introducing into the milk storage tank 1.
5) Dissolving the vitamins: according to the formula requirements, vitamin A, vitamin D, vitamin C, vitamin K1, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotinic acid, folic acid, pantothenic acid, biotin, choline and L-carnitine are added into a dissolving tank 2, stirred to be completely dissolved and then introduced into a milk storage tank 1.
6) Dissolving minerals: adding calcium, magnesium, ferrum, zinc and selenium into the dissolving tank 2 according to the formula requirements, stirring to completely dissolve, and introducing into the milk storage tank 1.
7) And (3) sterilization: the mixed solution is sterilized through a pipeline at the temperature of 121-135 ℃.
8) Homogenizing: homogenizing the sterilized milk under 10-14 Mpa.
9) Concentrating and drying: firstly, carrying out reduced pressure concentration, wherein the vacuum degree is 46-87Kpa, and the concentration is 15-27-degree Ba; the air inlet temperature is 165-190 ℃ and the air outlet temperature is 68-94 ℃, so that the biological activity and the nutrient content of most of proteins in the production process of the formula milk powder are ensured; finally, fluidized bed drying is carried out, the air inlet temperature is 35-95 ℃, and the fluidization speed is 0.05-3.5 m/s.
10) Adding other raw materials: according to the formula requirements, lactoferrin, bovine colostrum powder, N-acetylneuraminic acid, yeast beta-glucan, probiotics and DHA are respectively and uniformly mixed according to the proportion of 1:10 to (semi-finished milk powder), and then added into a dry mixer to be stirred for 20-40 min. (bovine colostrum powder, N-acetylneuraminic acid, yeast beta-glucan, DHA can also be added in step 5)
11) Packaging: and filling the stirred finished product powder in a clean workshop.
Optionally or alternatively, the milk powder preparation process provided by the invention adopts a dry process, and comprises the following steps:
1) unpacking: the raw materials such as the customized vegetable fat powder (vegetable oil, whey powder), the whole milk powder, the skimmed milk powder and the like are taken out of the outer package according to the required amount of the formula, and the inner package enters a workshop for temporarily placing the raw materials in a cleaning area through wind showering and ultraviolet sterilization.
2) Weighing small materials: according to the formula requirements, the vitamins, minerals, L-carnitine, choline, fructo-oligosaccharide, galacto-oligosaccharide, bovine colostrum powder, lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics, DHA and other small materials are weighed and subpackaged, and are sent to a mixing workshop for standby after being packaged and surface sterilized.
3) Mixing small materials 1: uniformly mixing lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics and DHA in a ratio of 1:10 to the semi-finished milk powder respectively.
4) Mixing small materials 2: and uniformly mixing the fructo-oligosaccharide, the galacto-oligosaccharide and the semi-finished product according to the ratio of 1: 10.
5) Mixing raw materials: adding vitamin A, vitamin D, vitamin C, vitamin K1, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotinic acid, folic acid, pantothenic acid, biotin, choline, L-carnitine, calcium, magnesium, iron, zinc and selenium, the mixed powder obtained in the step 3) and the bovine colostrum powder into the semi-finished milk powder according to the formula requirements, adding a dry mixing machine, and stirring for 20-40 min. .
6) Packaging: and filling the stirred finished product powder in a clean workshop.
In actual production, a factory can change the adding sequence and the process parameters of the raw materials according to actual conditions, and the whole process flow can be completed in one factory or multiple factories.
Example 1 milk powder for promoting development of immune system of children
Preparing materials:
the milk powder comprises: whole milk, cow/goat milk powder, cow/goat whey protein powder, lactose, cow colostrum powder (added amount: 1-10 g/100g milk powder), vegetable oil (sunflower seed oil, soybean oil), fructo-oligosaccharide, galacto-oligosaccharide, docosahexaenoic acid oil, L-carnitine tartrate, lactoferrin, N-acetylneuraminic acid (added amount: 10-50mg/100g milk powder), yeast beta-glucan (added amount: 30-100mg/100g milk powder), probiotics (Bifidobacterium lactis, Lactobacillus rhamnosus, lactococcus lactis subspecies lactis), choline chloride, magnesium chloride, calcium carbonate, ferrous sulfate, zinc sulfate, sodium selenite, vitamin A acetate, cholecalciferol, phytomenadione, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, cyanocobalamine, L-ascorbic acid, nicotinamide, folic acid, D-calcium pantothenate, D-biotin:
every 100g of milk powder is added with 10 hundred million CFU of bifidobacterium lactis, 10 hundred million CFU of lactobacillus rhamnosus and 10 hundred million of CFU of lactococcus lactis subspecies lactis
The type and amount of the probiotics can be adjusted according to actual conditions.
Nutrient composition table:
Figure BDA0002888256920000081
Figure BDA0002888256920000091
example 2 milk powder for promoting development of immune system of children
The milk powder comprises: raw cow/goat milk, cow/goat whey protein powder, lactose, cow colostrum powder (added amount: 1-10 g/100g milk powder), vegetable oil (sunflower seed oil, soybean oil), fructo-oligosaccharide, galacto-oligosaccharide, docosahexaenoic acid oil, L-carnitine tartrate, lactoferrin, N-acetylneuraminic acid (added amount: 10-50mg/100g milk powder), yeast beta-glucan (added amount: 30-100mg/100g milk powder), probiotics (bifidobacterium lactis, lactobacillus rhamnosus, lactococcus lactis subspecies lactis), choline chloride, magnesium chloride, calcium carbonate, ferrous sulfate, zinc sulfate, sodium selenite, vitamin A acetate, cholecalciferol, phytomenadione, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, cyanocobalamine, L-ascorbic acid, nicotinamide, folic acid, calcium D-pantothenate, D-biotin;
every 100g of milk powder is added with 10 hundred million CFU of bifidobacterium lactis, 10 hundred million CFU of lactobacillus rhamnosus and 10 hundred million of CFU of lactococcus lactis subspecies lactis.
The type and amount of the probiotics can be adjusted according to actual conditions.
Nutrient composition table:
Figure BDA0002888256920000101
Figure BDA0002888256920000111
example 3 milk powder for promoting development of immune system of children
The milk powder comprises: high oil whey powder (bovine/sheep whey protein powder, sunflower seed oil, soybean oil), whole milk powder, lactose, bovine colostrum powder (added amount: 1-10 g/100g milk powder), fructo-oligosaccharide, galacto-oligosaccharide, docosahexaenoic acid oil, L-carnitine tartrate, lactoferrin, N-acetylneuraminic acid (added amount: 10-50mg/100g milk powder), yeast beta-glucan (added amount: 30-100mg/100g milk powder), probiotics (Lactobacillus lactis, Lactobacillus rhamnosus, lactococcus lactis subspecies lactis), choline chloride, magnesium chloride, calcium carbonate, ferrous sulfate, zinc sulfate, sodium selenite, vitamin A acetate, cholecalciferol, phytomenadione, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, cyanocobalamin, L-ascorbic acid, nicotinamide, folic acid, calcium D-pantothenate, D-biotin;
every 100g of milk powder is added with 10 hundred million CFU of bifidobacterium lactis, 10 hundred million CFU of lactobacillus rhamnosus and 10 hundred million of CFU of lactococcus lactis subspecies lactis.
The type and amount of the probiotics can be adjusted according to actual conditions.
Nutrient composition table:
Figure BDA0002888256920000112
Figure BDA0002888256920000121
the process and formulation of this patent can be adjusted appropriately according to national regulations, changes in standards and actual conditions of the manufacturing plant without changing the final result.

Claims (9)

1. The formula of the milk powder beneficial to development of the immune system of children is characterized by comprising cow/goat milk, whey powder, lactose, cow colostrum powder, vegetable oil, fructo-oligosaccharide, galacto-oligosaccharide, docosahexaenoic acid grease, L-carnitine, lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics, choline, magnesium, calcium, iron, zinc, selenium, vitamin A, vitamin D, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, nicotinic acid, folic acid, pantothenic acid and biotin.
2. The milk powder formula for promoting development of immune system of children according to claim 1, wherein the bovine colostrum powder is added in an amount of 1-10 g/100g milk powder.
3. The formula of milk powder for promoting development of immune system of children as claimed in claim 1 or 2, wherein the amount of N-acetylneuraminic acid added is 10-50mg/100g of milk powder.
4. The milk powder formula for promoting development of immune system of children as claimed in claim 1 or 2, wherein the yeast β -glucan is added in an amount of 30-100mg/100g milk powder.
5. The milk powder formulation for the development of the immune system of children according to claim 1 or 2, wherein the probiotic bacteria are bifidobacterium lactis andor lactobacillus rhamnosus andor lactobacillus lactis subsp.
6. The formula of claim 5, wherein 10 million CFU of Bifidobacterium lactis, 10 million CFU of Lactobacillus rhamnosus, and 10 million CFU of lactococcus lactis subspecies lactis are added per 100g of the formula.
7. The milk powder formula for promoting the development of the immune system of children according to claim 1 or 2, wherein the nutrient content is as follows:
Figure FDA0002888256910000011
Figure FDA0002888256910000021
8. method for the production of a milk powder formula for the development of the immune system of children according to the preceding claims, comprising the following steps:
1) adding liquid milk: according to the formula requirement, introducing a specified amount of purified raw cow/goat milk or whole fat/skimmed milk into a milk storage tank 1; if the formula does not use liquid milk, adding treated purified water;
2) redissolving and treating the main materials: adding the pretreated purified water into the blending tank 1, adding solid raw materials such as whole milk powder, skimmed milk powder, whey powder, lactose and the like according to the formula requirement, stirring to completely dissolve, and introducing into the milk storage tank 1;
3) adding vegetable oil: adding vegetable oil into a milk storage tank 1 according to the formula requirement;
4) dissolving dietary fiber: adding fructo-oligosaccharide and galacto-oligosaccharide into the blending tank 2 according to the formula requirement, stirring to completely dissolve, and introducing into the milk storage tank 1;
5) dissolving the vitamins: adding vitamin A, vitamin D, vitamin C, vitamin K1, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotinic acid, folic acid, pantothenic acid, biotin, choline and L-carnitine into a dissolving tank 2 according to the formula requirements, stirring to completely dissolve, and then introducing into a milk storage tank 1;
6) dissolving minerals: adding calcium, magnesium, iron, zinc and selenium into the dissolving tank 2 according to the formula requirements, stirring to completely dissolve, and then introducing into the milk storage tank 1;
7) and (3) sterilization: sterilizing the mixed solution through a pipeline at the temperature of 121-135 ℃;
8) homogenizing: homogenizing the sterilized milk liquid under 10-14 Mpa;
9) concentrating and drying: firstly, carrying out reduced pressure concentration, wherein the vacuum degree is 46-87Kpa, and the concentration is 15-27-degree Ba; the air inlet temperature is 165-190 ℃ and the air outlet temperature is 68-94 ℃, so that the biological activity and the nutrient content of most of proteins in the production process of the formula milk powder are ensured; finally, fluidized bed drying is carried out, the air inlet temperature is 35-95 ℃, and the fluidization speed is 0.05-3.5 m/s;
10) adding other raw materials: uniformly mixing lactoferrin, bovine colostrum powder, N-acetylneuraminic acid, yeast beta-glucan, probiotics and DHA with the semi-finished milk powder according to the formula requirement in a ratio of 1:10, adding a dry mixer, and stirring for 20-40 min;
11) packaging: filling the stirred finished product powder in a clean workshop;
the bovine colostrum powder can be added in step 10); the bovine colostrum powder, N-acetylneuraminic acid, yeast beta-glucan and DHA can also be added in step 5).
9. Method for the production of a milk powder formula for the development of the immune system of children according to the preceding claims, comprising the following steps:
1) unpacking: removing external package of raw materials such as customized vegetable fat powder (vegetable oil, whey powder), whole milk powder, skimmed milk powder, etc., and allowing the internal package to enter into a workshop for temporarily storing raw materials in clean area by air showering and ultraviolet sterilization;
2) weighing small materials: according to the formula requirements, weighing and subpackaging vitamins, mineral substances, L-carnitine, choline, fructo-oligosaccharide, galacto-oligosaccharide, bovine colostrum powder, lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics and DHA small materials, packaging, sterilizing the surface, and then sending into a mixing workshop for later use;
3) mixing small materials 1: uniformly mixing lactoferrin, N-acetylneuraminic acid, yeast beta-glucan, probiotics and DHA with the semi-finished milk powder according to the proportion of 1:10 respectively;
4) mixing small materials 2: uniformly mixing fructo-oligosaccharide, galacto-oligosaccharide and semi-finished product according to the ratio of 1: 10;
5) mixing raw materials: adding vitamin A, vitamin D, vitamin C, vitamin K1, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotinic acid, folic acid, pantothenic acid, biotin, choline, L-carnitine, calcium, magnesium, iron, zinc and selenium, the mixed powder obtained in the step 3) and the bovine colostrum powder into the semi-finished milk powder according to the formula requirements, adding a dry mixing machine, and stirring for 20-40 min;
6) packaging: and filling the stirred finished product powder in a clean workshop.
CN202110020226.8A 2021-01-07 2021-01-07 Formula of milk powder beneficial to development of immune system of children and production method thereof Pending CN112772723A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2532062A1 (en) * 2005-01-14 2006-07-14 Nutrinor Cooperative Agro-Alimentaire Du Saguenay Lac St-Jean Food composition for maintaining and restoring digestive functions
CN104413334A (en) * 2013-08-30 2015-03-18 深圳华大基因科技有限公司 Edible composition as well as preparation method and application thereof
CN111184072A (en) * 2020-03-02 2020-05-22 上海育博营养食品有限公司 Milk powder beneficial to enhancing immunity and improving resistance and production method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2532062A1 (en) * 2005-01-14 2006-07-14 Nutrinor Cooperative Agro-Alimentaire Du Saguenay Lac St-Jean Food composition for maintaining and restoring digestive functions
CN104413334A (en) * 2013-08-30 2015-03-18 深圳华大基因科技有限公司 Edible composition as well as preparation method and application thereof
CN111184072A (en) * 2020-03-02 2020-05-22 上海育博营养食品有限公司 Milk powder beneficial to enhancing immunity and improving resistance and production method thereof

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