CN112717039A - Compound cocklebur fruit antibacterial powder and preparation method thereof - Google Patents

Compound cocklebur fruit antibacterial powder and preparation method thereof Download PDF

Info

Publication number
CN112717039A
CN112717039A CN202110164522.5A CN202110164522A CN112717039A CN 112717039 A CN112717039 A CN 112717039A CN 202110164522 A CN202110164522 A CN 202110164522A CN 112717039 A CN112717039 A CN 112717039A
Authority
CN
China
Prior art keywords
parts
compound
antibacterial powder
cocklebur fruit
fruit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110164522.5A
Other languages
Chinese (zh)
Inventor
卢金付
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202110164522.5A priority Critical patent/CN112717039A/en
Publication of CN112717039A publication Critical patent/CN112717039A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483—Gleditsia (locust)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses compound cocklebur fruit antibacterial powder and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The compound cocklebur fruit antibacterial powder is composed of the following components in parts by weight: 30-45 parts of cocklebur fruit, 25-35 parts of biond magnolia flower, 15-21 parts of costus root, 13-18 parts of wrinkled gianthyssop herb, 7-11 parts of centipeda minima, 4-7 parts of mint, 22-30 parts of pedicellus melo, 22-30 parts of Chinese honeylocust fruit, 13-16 parts of asteriscus Pseudosciaenae, 23-30 parts of angelica dahurica, 8-12 parts of Szechuan lovage rhizome, 2-5 parts of borneol, 4-9 parts of piper longum, 4-8 parts of asarum, 4-9 parts of cassia twig, 2-5 parts of grassleaf sweelflag rhizome and 4-8 parts of chlorhexidine acetate. The invention is used for disinfecting and bacteriostasis products, and has the effects of clearing heat, diminishing inflammation, dredging orifices, bacteriostasis and the like; pure Chinese medicinal preparation, no side effect.

Description

Compound cocklebur fruit antibacterial powder and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to compound cocklebur fruit antibacterial powder and a preparation method thereof.
Background
The traditional method for treating rhinitis is a pure traditional Chinese medicine therapy, a laser and puncture therapy and a traditional operation therapy, the three therapies have certain disadvantages in treating rhinitis, and patients are easy to relapse after being treated by the three therapies and cannot achieve the purpose of radical treatment. Some patients choose to use the different prescription to treat rhinitis, the different prescription is not scientifically proved, and side effects are easy to generate by blind use.
How to prepare the antibacterial powder for treating rhinitis by combining Chinese and western medicines is one of the hot spots in scientific research at the present stage, and the existing antibacterial product mainly takes hormone medicines and has side effects on human bodies.
Therefore, providing a natural and safe bacteriostatic powder is a problem that needs to be solved by those skilled in the art.
Disclosure of Invention
In view of the above, the invention provides a compound cocklebur fruit antibacterial powder and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
the compound cocklebur fruit antibacterial powder is composed of the following components in parts by weight: 30-45 parts of cocklebur fruit, 25-35 parts of biond magnolia flower, 15-21 parts of costus root, 13-18 parts of wrinkled gianthyssop herb, 7-11 parts of centipeda minima, 4-7 parts of mint, 22-30 parts of pedicellus melo, 22-30 parts of Chinese honeylocust fruit, 13-16 parts of asteriscus Pseudosciaenae, 23-30 parts of angelica dahurica, 8-12 parts of Szechuan lovage rhizome, 2-5 parts of borneol, 4-9 parts of piper longum, 4-8 parts of asarum, 4-9 parts of cassia twig, 2-5 parts of grassleaf sweelflag rhizome and 4-8 parts of chlorhexidine acetate.
Preferably: 35-40 parts of cocklebur fruit, 30-35 parts of magnolia flower, 15-18 parts of costus root, 14-16 parts of wrinkled gianthyssop herb, 8-10 parts of centipeda minima, 4-6 parts of mint, 26-30 parts of pedicellus melo, 25-30 parts of Chinese honeylocust fruit, 14-15 parts of asteriscus Pseudosciaenae, 28-30 parts of angelica dahurica, 10-11 parts of ligusticum wallichii, 3-4 parts of borneol, 5-8 parts of piper longi, 5-8 parts of asarum, 4-6 parts of cassia twig, 3-5 parts of rhizoma acori graminei and 5-7 parts of chlorhexidine acetate.
Preferably: 35 parts of cocklebur fruit, 35 parts of biond magnolia flower, 15 parts of costustoot, 15 parts of wrinkled gianthyssop herb, 9 parts of centipeda minima, 5 parts of mint, 30 parts of pedicellus melo, 30 parts of Chinese honeylocust fruit, 15 parts of asteriscus Pseudosciaenae, 30 parts of radix angelicae, 11 parts of ligusticum wallichii, 3 parts of borneol, 6 parts of piper longi, 8 parts of asarum, 5 parts of cassia twig, 5 parts of rhizoma acori graminei and 6 parts of chlorhexidine acetate.
The invention also provides a preparation method of the compound cocklebur fruit antibacterial powder, which comprises the following steps:
s1, weighing fructus Xanthii, flos Magnoliae, radix aucklandiae, herba Agastaches, herba Centipedae, herba Menthae, pedicellus melo, fructus Gleditsiae Abnormalis, asteriscus Pseudosciaenae, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, fructus Piperis Longi, herba asari, ramulus Cinnamomi, and rhizoma Acori Graminei, cutting into 30 mesh mixture, and soaking in water for 60-90 min; decocting the soaked mixture and water, extracting for 2-4 times, collecting and filtering to obtain filtrate, and naturally cooling;
s2, adding chlorhexidine acetate into the filtrate, putting the filtrate and chlorhexidine acetate into a concentration tank together, concentrating under reduced pressure at 60 ℃ until the relative density is 1.15-1.2, adding ethanol, standing for precipitation, concentrating under reduced pressure under the vacuum condition of-0.06 to-0.08 Mpa, taking the supernatant, recovering ethanol, and concentrating to 60 ℃ until the relative density is 1.35-1.4 to obtain an extract;
s3, heating the extract, keeping the temperature, performing spray drying to obtain the compound fructus Xanthii antibacterial powder, sterilizing, filling and sealing.
Preferably, the volume ratio of the mixture to the water decoction in the step S1 is 1: 16-20.
Preferably, the interval between the two juicing operations in the step S1 is 20-25 min.
Preferably, the alcohol content of the ethanol added in the step S2 is 65%.
Preferably, the temperature of the concentration under reduced pressure in the step S2 is 50 to 60 ℃.
Preferably, the temperature rise and holding temperature in the step S3 is 90 to 95 ℃.
The compound cocklebur fruit antibacterial powder of the invention has the following medicinal properties:
fructus xanthil: warm in nature, pungent and bitter in flavor. It enters lung meridian. Disperse wind-damp, dredge nasal orifice and kill parasites. They belong to the category of exterior-releasing herbs with pungent-warm property. Pharmacological research shows that the cocklebur fruit decoction has the functions of relieving cough, reducing blood sugar, lowering blood pressure, resisting bacteria, diminishing inflammation and resisting thrombin. Can be used for treating wind-cold headache, nasal discharge, rubella, pruritus, and arthralgia due to dampness. Or making into pill or powder. It can be decocted and washed with water or ground into powder for external application.
And (3) magnolia flower: warm in nature and pungent in flavor. It enters lung and stomach meridians. Dispelling pathogenic wind and cold, and dredging nasal orifice. Herbs with pungent and warm natured exterior-releasing herbs belong to the category of exterior-releasing herbs. Dispel wind, clear heat and remove toxicity. Can be used for treating rhinitis. Has effects in relieving anesthesia, resisting allergy, relieving inflammation, lowering blood pressure, stimulating uterus, resisting platelet aggregation, resisting microorganism, relieving pain, and improving microcirculation.
Costustoot: warm in nature, pungent and bitter in flavor. It enters spleen meridian, stomach meridian, large intestine meridian, triple energizer meridian and gallbladder meridian. Move qi and alleviate pain, invigorate spleen and promote digestion. Belongs to qi-regulating herbs. The root oil mainly contains costunolide, dehydrocostuslactone, costunolide, costunolic acid, costunolide, alpha-cyclocostunolide, mukusenolide, beta-sitosterol, syringin, etc.
Agastache rugosus: slightly warm in nature and pungent in flavor. It enters lung, spleen and stomach meridians. Fast qi, harmonize middle warmer, avoid filthy, and eliminate dampness. Belongs to qi-regulating herbs. The herba Agastaches decoction has effect in inhibiting various pathogenic fungi such as Trichophyton schoenleinii, etc., and the ether leachate and alcohol leachate can also inhibit various pathogenic fungi. The decoction has effect in inhibiting leptospira. The flavonoids in herba Agastaches have antiviral effect.
Centipeda minima: warm in nature and pungent in flavor. It enters lung and liver meridians. Induce nasal obstruction and relieve cough. They belong to the category of exterior-releasing herbs with pungent-warm property. It is indicated for nasal obstruction, nasal discharge and headache due to affection of exogenous wind-cold; the nasal obstruction is obstructed; cough with dyspnea due to cold-phlegm, cough due to wind-cold-phlegm; headache, toothache, traumatic pain, rheumatic arthralgia, sore, carbuncle, acute swelling and pain, acute eruptive disease, dysentery, abdominal pain, tinea, sore, and pruritus.
Mint: cool in nature and pungent in flavor. It enters lung and liver meridians. Disperse wind-heat, clear head and eyes, promote eruption. Herbs for releasing exterior syndrome with pungent and cool natured drugs belong to the category of exterior-releasing herbs. Has effects in inducing perspiration, relieving fever, relieving gastrointestinal smooth muscle spasm, exciting central nerve, promoting secretion of respiratory tract gland, and relieving inflammation and spasm; it can also stimulate nerve ending cold receptor to produce cold feeling, and reversely cause the change of deep tissue blood vessel to play the roles of diminishing inflammation, relieving pain and relieving itching; has certain inhibiting effect on gram-resistant gram-negative coccus, bacillus and various viruses.
Pedicel: cold in nature and bitter in taste. It enters spleen, stomach and liver meridians. Induce vomiting of phlegm and food, remove dampness and remove jaundice. It belongs to emetics. Can be used for treating apoplexy, epilepsy, pharyngitis, excessive phlegm and saliva, dyspnea, indigestion, chest and abdominal pain, and jaundice due to damp-heat pathogen. Protecting liver; resisting cancer; enhancing cellular immune function; anti-inflammatory and contraceptive; causing vomiting. The product mainly contains amino acids, cucurbitacin B, cucurbitacin D, cucurbitacin E, iso-cucurbitacin beta, alpha-spinasterol, etc.
And (2) Chinese honeylocust fruit: warm in nature, pungent and salty in flavor. Has little toxicity. It enters lung and large intestine meridians. Inducing resuscitation, eliminating phlegm, resolving hard mass, relieving swelling, moistening dryness and relaxing bowels. It belongs to emetics. Contains multiple saponins. It also contains fisetin, fustin, betulinic acid, betulin, and friedelin.
Fish brain stones: dissolve stones, treat stranguria and diminish inflammation. It is used to treat urolithiasis, dysuria, otitis media, rhinitis, and cerebral hemorrhage. The asteriscus Pseudosciaenae has effects of inducing diuresis for treating stranguria, and clearing away heat and toxic materials. It is often used to treat urolithiasis, stranguria with urine, rhinitis, suppurative otitis media, etc.
Radix angelicae: warm in nature and pungent in flavor. It enters stomach meridian, large intestine meridian and lung meridian. Dispelling pathogenic wind, removing dampness, inducing resuscitation, relieving pain, relieving swelling, and expelling pus. Herbs with pungent and warm natured exterior-releasing herbs belong to the category of exterior-releasing herbs. Has good analgesic effect, especially good effect on headache, and has effects of removing toxic substance and relieving inflammation. Recently, it has been found that coronary artery has a dilating effect, and coronary heart disease can be considered.
Ligusticum wallichii: warm in nature and pungent in flavor. It enters liver meridian, gallbladder meridian and pericardium meridian. Promote blood circulation and move qi, dispel wind and alleviate pain. Belongs to the category of blood-activating and stasis-resolving herbs. Can be used for treating thoracic obstruction, cardialgia, pricking pain in chest and hypochondrium, traumatic injury, menoxenia, amenorrhea, dysmenorrhea, addictions, abdominal pain, headache, and rheumatalgia. Effects on the cardiovascular and cerebrovascular System: has inhibitory effect on heart; can expand blood vessels and reduce blood pressure; increase coronary flow; has protective effect on myocardial and reperfusion injury; improving microcirculation; improving cerebral circulation and cerebral ischemia.
Borneol: cold in nature, pungent and bitter in flavor. They enter heart, spleen and lung meridians. Inducing resuscitation, refreshing mind, clearing heat and relieving pain. Belongs to the field of resuscitation inducing medicine. Can inhibit central nervous system, has obvious sedative and analgesic effects, and can promote growth and division of glial cells; has antiinflammatory, antibacterial, and antifertility effects, and can interact with other medicines such as tetramethylpyrazine and salicylic acid. The topical application has slight irritation to sensory nerve, and has analgesic and antiseptic effects.
After drawing: warm middle energizer and dispel cold, warm yang and resolve pain. It is mainly used to treat abdominal cold pain, vomiting and diarrhea, headache, toothache, nasosinusitis, coronary heart disease and severe pain.
Asarum: dispel wind, dispel cold, move water and induce resuscitation. It is indicated for wind-cold headache, nasosinusitis, toothache, phlegm-fluid cough, wind-damp arthralgia. It can be used for treating headache due to wind-cold type common cold or wind-cold type common cold, and can be combined with herba Ephedrae and rhizoma Ligustici. Can be used for treating muscle and joint pain due to pathogenic cold entering collaterals.
Cassia twig: pungent and sweet in flavor and warm in nature. It enters bladder meridian, heart meridian and lung meridian. Releasing exterior and relieving exterior syndrome, warming meridians and promoting blood circulation, supporting yang to transform qi, and calming the adverse-rising energy, and belongs to the pungent-warm exterior-releasing herbs. Has certain antibacterial and antiviral effects; has antipyretic, analgesic, tranquilizing, and anticonvulsive effects on central system; has obvious anti-inflammatory effect; can increase myocardial nutritional blood flow, and has antiallergic and anticoagulant effects.
By adopting the technical scheme, the invention has the following beneficial effects:
the invention is used for preparing the disinfection and bacteriostasis powder, and has the effects of clearing heat, diminishing inflammation, dredging orifices, bacteriostasis and the like; the Chinese medicinal preparation has no side effect. The invention is prepared based on a scientific formula, is matched with exquisite ingredients, adopts cocklebur fruit as a main material, is added with various traditional Chinese medicine auxiliary materials, has interaction, is anti-inflammatory and blood-cooling, is resuscitation-inducing and bacteriostatic, and is natural and safe.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
embodiment 1 discloses a compound cocklebur fruit antibacterial powder and a preparation method thereof.
The compound cocklebur fruit antibacterial powder is composed of the following components in parts by weight: 35 parts of cocklebur fruit, 35 parts of biond magnolia flower, 15 parts of costustoot, 15 parts of wrinkled gianthyssop herb, 9 parts of centipeda minima, 5 parts of mint, 30 parts of pedicellus melo, 30 parts of Chinese honeylocust fruit, 15 parts of asteriscus Pseudosciaenae, 30 parts of radix angelicae, 11 parts of ligusticum wallichii, 3 parts of borneol, 6 parts of piper longi, 8 parts of asarum, 5 parts of cassia twig, 5 parts of rhizoma acori graminei and 6 parts of chlorhexidine acetate.
A preparation method of compound cocklebur fruit antibacterial powder comprises the following specific steps:
s1, weighing fructus Xanthii, flos Magnoliae, radix aucklandiae, herba Agastaches, herba Centipedae, herba Menthae, pedicellus melo, fructus Gleditsiae Abnormalis, asteriscus Pseudosciaenae, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, fructus Piperis Longi, herba asari, ramulus Cinnamomi, and rhizoma Acori Graminei, cutting into 30 mesh mixture, and soaking in water for 60 min; decocting the mixture and water at a volume ratio of 1:16, extracting the decoction for 2-4 times at an interval of 20-25min, collecting and filtering to obtain filtrate, and naturally cooling;
s2, adding chlorhexidine acetate into the filtrate, putting the filtrate into a concentration tank together, concentrating under reduced pressure at 60 ℃ until the relative density is 1.15-1.2, adding ethanol until the ethanol content is 65%, standing for precipitation, concentrating under reduced pressure under-0.08 Mpa vacuum condition, collecting supernatant, recovering ethanol, concentrating under reduced pressure at 50-60 ℃ until the relative density is 1.35-1.4 when the filtrate is concentrated to 60 ℃, and obtaining extract;
s3, heating the extract, keeping the temperature at 90 ℃, performing spray drying to obtain the compound cocklebur fruit antibacterial powder, sterilizing, filling and sealing.
Example 2:
embodiment 2 discloses a compound cocklebur fruit antibacterial powder and a preparation method thereof.
The compound cocklebur fruit antibacterial powder is composed of the following components in parts by weight: 35 parts of cocklebur fruit, 30 parts of biond magnolia flower, 15 parts of costustoot, 14 parts of wrinkled gianthyssop herb, 8 parts of centipeda minima, 4 parts of mint, 26 parts of pedicellus melo, 25 parts of Chinese honeylocust fruit, 14 parts of asteriscus Pseudosciaenae, 28 parts of angelica dahurica, 10 parts of Szechuan lovage rhizome, 3 parts of borneol, 5 parts of piper longi, 5 parts of asarum, 4 parts of cassia twig, 3 parts of grassleaf sweelflag rhizome and 5 parts of chlorhexidine acetate.
A preparation method of compound cocklebur fruit antibacterial powder comprises the following specific steps:
s1, weighing fructus Xanthii, flos Magnoliae, radix aucklandiae, herba Agastaches, herba Centipedae, herba Menthae, pedicellus melo, fructus Gleditsiae Abnormalis, asteriscus Pseudosciaenae, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, fructus Piperis Longi, herba asari, ramulus Cinnamomi, and rhizoma Acori Graminei, cutting into 30 mesh mixture, and soaking in water for 70 min; decocting the mixture and water at a volume ratio of 1:17, extracting the decoction for 2-4 times at an interval of 20-25min, collecting and filtering to obtain filtrate, and naturally cooling;
s2, adding chlorhexidine acetate into the filtrate, putting the filtrate into a concentration tank together, concentrating under reduced pressure at 60 ℃ until the relative density is 1.15-1.2, adding ethanol until the ethanol content is 65%, standing for precipitation, concentrating under reduced pressure under-0.06 Mpa vacuum condition, collecting supernatant, recovering ethanol, concentrating under reduced pressure at 50-60 ℃ until the relative density is 1.35-1.4 when the filtrate is concentrated to 60 ℃, and obtaining extract;
s3, heating the extract, keeping the temperature at 93 ℃, performing spray drying to obtain the compound cocklebur fruit antibacterial powder, sterilizing, filling and sealing.
Example 3:
embodiment 3 discloses a compound cocklebur fruit antibacterial powder and a preparation method thereof.
The compound cocklebur fruit antibacterial powder is composed of the following components in parts by weight: 40 parts of cocklebur fruit, 35 parts of biond magnolia flower, 18 parts of costustoot, 16 parts of wrinkled gianthyssop herb, 10 parts of centipeda minima, 6 parts of mint, 30 parts of pedicellus melo, 30 parts of Chinese honeylocust fruit, 15 parts of asteriscus Pseudosciaenae, 30 parts of radix angelicae, 11 parts of ligusticum wallichii, 4 parts of borneol, 8 parts of piper longi, 8 parts of asarum, 6 parts of cassia twig, 5 parts of rhizoma acori graminei and 7 parts of chlorhexidine acetate.
A preparation method of compound cocklebur fruit antibacterial powder comprises the following specific steps:
s1, weighing fructus Xanthii, flos Magnoliae, radix aucklandiae, herba Agastaches, herba Centipedae, herba Menthae, pedicellus melo, fructus Gleditsiae Abnormalis, asteriscus Pseudosciaenae, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, fructus Piperis Longi, herba asari, ramulus Cinnamomi, and rhizoma Acori Graminei, cutting into 30 mesh mixture, and soaking in water for 80 min; decocting the mixture and water at a volume ratio of 1:18, extracting the decoction for 2-4 times at an interval of 20-25min, collecting and filtering to obtain filtrate, and naturally cooling;
s2, adding chlorhexidine acetate into the filtrate, putting the filtrate into a concentration tank together, concentrating under reduced pressure at 60 ℃ until the relative density is 1.15-1.2, adding ethanol until the ethanol content is 65%, standing for precipitation, concentrating under reduced pressure under-0.07 Mpa vacuum condition, collecting supernatant, recovering ethanol, concentrating under reduced pressure at 50-60 ℃ until the relative density is 1.35-1.4 when the filtrate is concentrated to 60 ℃, and obtaining extract;
s3, heating the extract, keeping the temperature at 94 ℃, performing spray drying to obtain the compound cocklebur fruit antibacterial powder, sterilizing, filling and sealing.
Example 4:
embodiment 4 discloses a compound cocklebur fruit antibacterial powder and a preparation method thereof.
The compound cocklebur fruit antibacterial powder is composed of the following components in parts by weight: 30 parts of cocklebur fruit, 25 parts of biond magnolia flower, 15 parts of costustoot, 13 parts of wrinkled gianthyssop herb, 7 parts of centipeda minima, 4 parts of mint, 22 parts of pedicellus melo, 22 parts of Chinese honeylocust fruit, 13 parts of asteriscus Pseudosciaenae, 23 parts of angelica dahurica, 8 parts of Szechuan lovage rhizome, 2 parts of borneol, 4 parts of piper longum, 4 parts of asarum, 4 parts of cassia twig, 2 parts of grassleaf sweelflag rhizome and 4 parts of chlorhexidine acetate.
A preparation method of compound cocklebur fruit antibacterial powder comprises the following specific steps:
s1, weighing fructus Xanthii, flos Magnoliae, radix aucklandiae, herba Agastaches, herba Centipedae, herba Menthae, pedicellus melo, fructus Gleditsiae Abnormalis, asteriscus Pseudosciaenae, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, fructus Piperis Longi, herba asari, ramulus Cinnamomi, and rhizoma Acori Graminei, cutting into 30 mesh mixture, and soaking in water for 75 min; decocting the mixture and water at a volume ratio of 1:18, extracting the decoction for 2-4 times at an interval of 20-25min, collecting and filtering to obtain filtrate, and naturally cooling;
s2, adding chlorhexidine acetate into the filtrate, putting the filtrate into a concentration tank together, concentrating under reduced pressure at 60 ℃ until the relative density is 1.15-1.2, adding ethanol until the ethanol content is 65%, standing for precipitation, concentrating under reduced pressure under-0.08 Mpa vacuum condition, collecting supernatant, recovering ethanol, concentrating under reduced pressure at 50-60 ℃ until the relative density is 1.35-1.4 when the filtrate is concentrated to 60 ℃, and obtaining extract;
s3, heating the extract, keeping the temperature at 92 ℃, performing spray drying to obtain the compound cocklebur fruit antibacterial powder, sterilizing, filling and sealing.
Example 5:
embodiment 5 discloses a compound cocklebur fruit antibacterial powder and a preparation method thereof.
The compound cocklebur fruit antibacterial powder is composed of the following components in parts by weight: 45 parts of cocklebur fruit, 35 parts of biond magnolia flower, 21 parts of costustoot, 18 parts of wrinkled gianthyssop herb, 11 parts of centipeda minima, 7 parts of mint, 30 parts of pedicellus melo, 30 parts of Chinese honeylocust fruit, 16 parts of asteriscus Pseudosciaenae, 30 parts of radix angelicae, 12 parts of ligusticum wallichii, 5 parts of borneol, 9 parts of piper longituba, 8 parts of asarum, 9 parts of cassia twig, 5 parts of rhizoma acori graminei and 8 parts of chlorhexidine acetate.
A preparation method of compound cocklebur fruit antibacterial powder comprises the following specific steps:
s1, weighing fructus Xanthii, flos Magnoliae, radix aucklandiae, herba Agastaches, herba Centipedae, herba Menthae, pedicellus melo, fructus Gleditsiae Abnormalis, asteriscus Pseudosciaenae, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, fructus Piperis Longi, herba asari, ramulus Cinnamomi, and rhizoma Acori Graminei, cutting into 30 mesh mixture, and soaking in water for 90 min; decocting the mixture and water at a volume ratio of 1:20, decocting the soaked mixture and water for 2-4 times at an interval of 20-25min, collecting and filtering to obtain filtrate, and naturally cooling;
s2, adding chlorhexidine acetate into the filtrate, putting the filtrate into a concentration tank together, concentrating under reduced pressure at 60 ℃ until the relative density is 1.15-1.2, adding ethanol until the ethanol content is 65%, standing for precipitation, concentrating under reduced pressure under-0.06 Mpa vacuum condition, collecting supernatant, recovering ethanol, concentrating under reduced pressure at 50-60 ℃ until the relative density is 1.35-1.4 when the filtrate is concentrated to 60 ℃, and obtaining extract;
s3, heating the extract, keeping the temperature at 95 ℃, performing spray drying to obtain the compound cocklebur fruit antibacterial powder, sterilizing, filling and sealing.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (9)

1. The compound cocklebur fruit antibacterial powder is characterized by comprising the following components in parts by weight: 30-45 parts of cocklebur fruit, 25-35 parts of biond magnolia flower, 15-21 parts of costus root, 13-18 parts of wrinkled gianthyssop herb, 7-11 parts of centipeda minima, 4-7 parts of mint, 22-30 parts of pedicellus melo, 22-30 parts of Chinese honeylocust fruit, 13-16 parts of asteriscus Pseudosciaenae, 23-30 parts of angelica dahurica, 8-12 parts of Szechuan lovage rhizome, 2-5 parts of borneol, 4-9 parts of piper longum, 4-8 parts of asarum, 4-9 parts of cassia twig, 2-5 parts of grassleaf sweelflag rhizome and 4-8 parts of chlorhexidine acetate.
2. The compound cocklebur fruit antibacterial powder is characterized by comprising the following components in parts by weight: 35-40 parts of cocklebur fruit, 30-35 parts of magnolia flower, 15-18 parts of costus root, 14-16 parts of wrinkled gianthyssop herb, 8-10 parts of centipeda minima, 4-6 parts of mint, 26-30 parts of pedicellus melo, 25-30 parts of Chinese honeylocust fruit, 14-15 parts of asteriscus Pseudosciaenae, 28-30 parts of angelica dahurica, 10-11 parts of ligusticum wallichii, 3-4 parts of borneol, 5-8 parts of piper longi, 5-8 parts of asarum, 4-6 parts of cassia twig, 3-5 parts of rhizoma acori graminei and 5-7 parts of chlorhexidine acetate.
3. The compound cocklebur fruit antibacterial powder is characterized by comprising the following components in parts by weight: 35 parts of cocklebur fruit, 35 parts of biond magnolia flower, 15 parts of costustoot, 15 parts of wrinkled gianthyssop herb, 9 parts of centipeda minima, 5 parts of mint, 30 parts of pedicellus melo, 30 parts of Chinese honeylocust fruit, 15 parts of asteriscus Pseudosciaenae, 30 parts of radix angelicae, 11 parts of ligusticum wallichii, 3 parts of borneol, 6 parts of piper longi, 8 parts of asarum, 5 parts of cassia twig, 5 parts of rhizoma acori graminei and 6 parts of chlorhexidine acetate.
4. The preparation method of the compound xanthium sibiricum antibacterial powder according to any one of claims 1 to 3, which is characterized by comprising the following specific steps:
s1, weighing fructus Xanthii, flos Magnoliae, radix aucklandiae, herba Agastaches, herba Centipedae, herba Menthae, pedicellus melo, fructus Gleditsiae Abnormalis, asteriscus Pseudosciaenae, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, fructus Piperis Longi, herba asari, ramulus Cinnamomi, and rhizoma Acori Graminei, cutting into 30 mesh mixture, and soaking in water for 60-90 min; decocting the soaked mixture and water, extracting for 2-4 times, collecting and filtering to obtain filtrate, and naturally cooling;
s2, adding chlorhexidine acetate into the filtrate, putting the filtrate and chlorhexidine acetate into a concentration tank together, concentrating under reduced pressure at 60 ℃ until the relative density is 1.15-1.2, adding ethanol, standing for precipitation, concentrating under reduced pressure under the vacuum condition of-0.06 to-0.08 Mpa, taking the supernatant, recovering ethanol, and concentrating to 60 ℃ until the relative density is 1.35-1.4 to obtain an extract;
s3, heating the extract, keeping the temperature, performing spray drying to obtain the compound fructus Xanthii antibacterial powder, sterilizing, filling and sealing.
5. The preparation method of the compound xanthium sibiricum antibacterial powder according to claim 4, wherein the volume ratio of the mixture to the water decoction in the step S1 is 1: 16-20.
6. The method for preparing the compound xanthium sibiricum antibacterial powder according to claim 4, wherein the interval between two juicing operations in the step S1 is 20-25 min.
7. The method for preparing the compound xanthium sibiricum antibacterial powder according to claim 4, wherein the alcohol content of the ethanol added in the step S2 is 65%.
8. The method for preparing the compound xanthium sibiricum antibacterial powder according to claim 4, wherein the temperature of the reduced pressure concentration in the step S2 is 50-60 ℃.
9. The method for preparing the compound xanthium sibiricum antibacterial powder according to claim 4, wherein the temperature rise and the temperature preservation temperature in the step S3 are 90-95 ℃.
CN202110164522.5A 2021-02-05 2021-02-05 Compound cocklebur fruit antibacterial powder and preparation method thereof Pending CN112717039A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110164522.5A CN112717039A (en) 2021-02-05 2021-02-05 Compound cocklebur fruit antibacterial powder and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110164522.5A CN112717039A (en) 2021-02-05 2021-02-05 Compound cocklebur fruit antibacterial powder and preparation method thereof

Publications (1)

Publication Number Publication Date
CN112717039A true CN112717039A (en) 2021-04-30

Family

ID=75596238

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110164522.5A Pending CN112717039A (en) 2021-02-05 2021-02-05 Compound cocklebur fruit antibacterial powder and preparation method thereof

Country Status (1)

Country Link
CN (1) CN112717039A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114699375A (en) * 2022-05-18 2022-07-05 讷河市忠海中医医院 Traditional Chinese medicine preparation for treating rhinitis and using method

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1334113A (en) * 2001-08-09 2002-02-06 牛海龙 Prescription of powdered Chinese medicine for mask to treat rhinitis
CN1446570A (en) * 2003-04-25 2003-10-08 赵世海 Externally applied agent for preventing infectious disease in respiratory tract as well as preparation method
CN105663243A (en) * 2016-03-28 2016-06-15 河南邦瑞特实业有限公司 Traditional Chinese medicinal composition for treating rhinitis and/or nasosinusitis and drug of traditional Chinese medicinal composition
CN106265966A (en) * 2016-10-21 2017-01-04 张有强 A kind of Chinese medicine treating sinusitis, allergic rhinitis, nasal conchae hypertrophy
CN107334817A (en) * 2017-06-30 2017-11-10 郑州澍青医学高等专科学校 A kind of Chinese medicine for treating nasosinusitis
CN108542987A (en) * 2018-07-06 2018-09-18 邵显武 A kind of Chinese medicine for treating rhinitis composition and preparation method thereof
CN108619242A (en) * 2018-08-17 2018-10-09 深圳神思汉方生物科技有限公司 A kind of rhinitis ointment

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1334113A (en) * 2001-08-09 2002-02-06 牛海龙 Prescription of powdered Chinese medicine for mask to treat rhinitis
CN1446570A (en) * 2003-04-25 2003-10-08 赵世海 Externally applied agent for preventing infectious disease in respiratory tract as well as preparation method
CN105663243A (en) * 2016-03-28 2016-06-15 河南邦瑞特实业有限公司 Traditional Chinese medicinal composition for treating rhinitis and/or nasosinusitis and drug of traditional Chinese medicinal composition
CN106265966A (en) * 2016-10-21 2017-01-04 张有强 A kind of Chinese medicine treating sinusitis, allergic rhinitis, nasal conchae hypertrophy
CN107334817A (en) * 2017-06-30 2017-11-10 郑州澍青医学高等专科学校 A kind of Chinese medicine for treating nasosinusitis
CN108542987A (en) * 2018-07-06 2018-09-18 邵显武 A kind of Chinese medicine for treating rhinitis composition and preparation method thereof
CN108619242A (en) * 2018-08-17 2018-10-09 深圳神思汉方生物科技有限公司 A kind of rhinitis ointment

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
佚名: "付济华：鼻窦炎、鼻息肉秘方", 《HTTP://WWW.360DOC.CN/MIP/843662485.HTML》 *
佚名: "鼻炎配方公开", 《HTTP://WWW.360DOC.COM/CONTENT/16/1214/01/8074284_614496386.SHTML》 *
张学安: "复方苍耳散塞鼻治疗副鼻窦炎", 《陕西中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114699375A (en) * 2022-05-18 2022-07-05 讷河市忠海中医医院 Traditional Chinese medicine preparation for treating rhinitis and using method

Similar Documents

Publication Publication Date Title
CN103070961B (en) Chinese medicinal anti-bacteria health care foot-massage solution and preparation method thereof
CN103202880B (en) Medicine for treating allergic rhinitis and method for preparing medicine
CN104524146A (en) Traditional Chinese medicine composition for prevention and adjuvant treatment of hypertensive, hyperlipidemia and hyperglycemia and application of traditional Chinese medicine composition
CN103768526A (en) External ointment for treating haemorrhoids
CN112717039A (en) Compound cocklebur fruit antibacterial powder and preparation method thereof
CN102068527A (en) Medicine and treatment method for eradication of whelk
CN101612226B (en) Chinese medicinal preparation for treating cold
CN110652544A (en) Pharmaceutical composition for treating rhinitis and preparation method thereof
CN105250427A (en) Pharmaceutical composition for treating heart diseases
CN104958581A (en) Chinese herbal preparation for treating epifolliculitis and preparing method of Chinese herbal preparation for treating epifolliculitis
CN110946900A (en) Qi-tonifying cold-dispelling decoction for allergic rhinitis
CN105853866A (en) Method for preparing Chinese herbal medicine composition for treating bedsore
CN104042923A (en) Externally-applied cream for treating whelk
CN104189489A (en) Medicament with effect of treating chronic eczema and preparation method thereof
CN102228567A (en) Medicine for treating trigeminal neuralgia
CN103860990B (en) Coronary heart disease promoting blood circulation to remove obstruction in the collateral powder and preparation method
CN112494627B (en) Traditional Chinese medicine composition for treating exogenous fever as well as preparation method and application thereof
CN116270419A (en) External traditional Chinese medicine wine and preparation method and application thereof
CN104189083A (en) Chinese herbal preparation for treating acute maxillary sinusitis
CN105343688A (en) Medicine composition for treating myocardial infarction and application thereof
CN105833108A (en) Traditional Chinese medicine composition for treating gall-stone
CN104127804A (en) Traditional Chinese medicine capable of treating diabetic foot ulcer
CN104887823A (en) Traditional Chinese medicine composition for treating nasopharyngeal carcinoma and administration method thereof
CN104606447A (en) Traditional Chinese medicine preparation for treating exogenous fever
CN105381125B (en) Traditional Chinese medicine composition for preventing and treating influenza as well as preparation method and application thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20210430

RJ01 Rejection of invention patent application after publication