CN112672741A - 用于治疗癌症的双功能组合物 - Google Patents

用于治疗癌症的双功能组合物 Download PDF

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CN112672741A
CN112672741A CN201980038420.XA CN201980038420A CN112672741A CN 112672741 A CN112672741 A CN 112672741A CN 201980038420 A CN201980038420 A CN 201980038420A CN 112672741 A CN112672741 A CN 112672741A
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cancer
dna
pnd
cells
ligand
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Chinese (zh)
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雷纳托·阿奎莱拉
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Amachetika Ltd
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Amachetika Ltd
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Priority claimed from AU2018902181A external-priority patent/AU2018902181A0/en
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
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  • Organic Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201980038420.XA 2018-06-19 2019-06-19 用于治疗癌症的双功能组合物 Pending CN112672741A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2018902181 2018-06-19
AU2018902181A AU2018902181A0 (en) 2018-06-19 Bifunctional compositions for the treatment of cancer
PCT/IB2019/055130 WO2019244050A1 (en) 2018-06-19 2019-06-19 Bifunctional compositions for the treatment of cancer

Publications (1)

Publication Number Publication Date
CN112672741A true CN112672741A (zh) 2021-04-16

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CN201980038420.XA Pending CN112672741A (zh) 2018-06-19 2019-06-19 用于治疗癌症的双功能组合物

Country Status (16)

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US (2) US12201626B2 (https=)
EP (1) EP3793544B1 (https=)
JP (1) JP7510411B2 (https=)
CN (1) CN112672741A (https=)
AU (1) AU2019291491B2 (https=)
BR (1) BR112020025946A2 (https=)
CA (1) CA3102051A1 (https=)
CL (1) CL2020003306A1 (https=)
GB (1) GB2587172B (https=)
IL (1) IL279609B2 (https=)
MX (1) MX2020014096A (https=)
MY (1) MY206540A (https=)
PH (1) PH12020552171A1 (https=)
RU (1) RU2764175C1 (https=)
SG (1) SG11202011503YA (https=)
WO (1) WO2019244050A1 (https=)

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CN115317625A (zh) * 2021-12-24 2022-11-11 南通大学附属医院 一种小干扰rna在制备改善鼻咽癌预后的药物中的应用
CN119064582A (zh) * 2024-09-02 2024-12-03 南方医科大学南方医院 RIPK1 O-GlcNAc糖基化抑制剂在制备增强肾细胞癌舒尼替尼敏感性药物中的应用

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US20220306603A1 (en) * 2019-06-12 2022-09-29 The Governors Of The University Of Alberta Targeting dna repair in tumor cells via inhibition of ercc1-xpf
KR20220140515A (ko) 2020-01-13 2022-10-18 버지 애널리틱스, 인크. 치환된 피라졸로-피리미딘 및 그의 용도
CN114511462B (zh) * 2022-02-11 2023-04-18 电子科技大学 一种视觉图像增强方法
WO2025251699A1 (zh) * 2024-06-07 2025-12-11 北京三博脑科医院有限公司 一种硝唑尼特及其药学上可接受的盐在制备抗造釉细胞型颅咽管瘤药物中的应用

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US10512641B2 (en) * 2015-06-01 2019-12-24 University Of Kentucky Research Foundation Chloroquine induction par-4 and treatment of cancer
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CN103570711A (zh) * 2012-07-24 2014-02-12 中国科学院上海药物研究所 一种咯萘啶类化合物及其用途

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王树滨: "咯萘啶逆转肿瘤耐药研究" *

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* Cited by examiner, † Cited by third party
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CN115317625A (zh) * 2021-12-24 2022-11-11 南通大学附属医院 一种小干扰rna在制备改善鼻咽癌预后的药物中的应用
CN115317625B (zh) * 2021-12-24 2023-08-08 南通大学附属医院 一种小干扰rna在制备改善鼻咽癌预后的药物中的应用
CN119064582A (zh) * 2024-09-02 2024-12-03 南方医科大学南方医院 RIPK1 O-GlcNAc糖基化抑制剂在制备增强肾细胞癌舒尼替尼敏感性药物中的应用
CN119064582B (zh) * 2024-09-02 2025-05-27 南方医科大学南方医院 RIPK1 O-GlcNAc糖基化抑制剂在制备增强肾细胞癌舒尼替尼敏感性药物中的应用

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