CN112619907B - Device for automatically separating and extracting PRP (pulse repetition program) - Google Patents

Device for automatically separating and extracting PRP (pulse repetition program) Download PDF

Info

Publication number
CN112619907B
CN112619907B CN202011375261.3A CN202011375261A CN112619907B CN 112619907 B CN112619907 B CN 112619907B CN 202011375261 A CN202011375261 A CN 202011375261A CN 112619907 B CN112619907 B CN 112619907B
Authority
CN
China
Prior art keywords
injector
separation
injection
needle head
box
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202011375261.3A
Other languages
Chinese (zh)
Other versions
CN112619907A (en
Inventor
程帅
李锋
童亚
马全
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan Biying Biotechnology Co ltd
Original Assignee
Wuhan Biying Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhan Biying Biotechnology Co ltd filed Critical Wuhan Biying Biotechnology Co ltd
Priority to CN202011375261.3A priority Critical patent/CN112619907B/en
Publication of CN112619907A publication Critical patent/CN112619907A/en
Application granted granted Critical
Publication of CN112619907B publication Critical patent/CN112619907B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • B04B5/0421Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes pivotably mounted
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B11/00Feeding, charging, or discharging bowls
    • B04B11/04Periodical feeding or discharging; Control arrangements therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B13/00Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B15/00Other accessories for centrifuges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B9/00Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/02Electric motor drives
    • B04B9/04Direct drive
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B9/00Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/14Balancing rotary bowls ; Schrappers
    • B04B9/146Unbalance detection devices

Landscapes

  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)

Abstract

The invention provides a device for automatically separating and extracting PRP (platelet Rich plasma), which comprises a workbench, wherein a blood collection tube placing and gravity sensing device, a counterweight water injection device, a centrifugal driving device, a mechanical extraction device and an injector and needle head separation and recovery device are sequentially arranged on the workbench according to working procedures; a first sliding rail, a second sliding rail, a first sliding rod and a second sliding rod are respectively arranged on two sides of the workbench, and the first sliding rod and the second sliding rod both span the workbench and are arranged with the first sliding rail and the second sliding rail; the device mainly comprises a main body, a separating device, a PRP automatic interval detection device, a PRP automatic extraction device, a four-coordinate transmission device, an injector and needle automatic assembly device, an injector and needle separation and automatic capping device, a finished product storage device, a separating tube counterweight device, an induction device and the like.

Description

Device for automatically separating and extracting PRP (pulse repetition program)
Technical Field
The invention relates to the technical field of blood separation devices, in particular to a device for automatically separating and extracting PRP.
Background
Since the mid-nineties of the last century, PRP is widely used in various surgical, cardiac and plastic procedures, and is now widely used in medical and cosmetic fields. However, how to conveniently and rapidly extract PRP with high concentration and high quality from blood is the key to PRP operation. At present, PRP is well clinically applied to medical operation treatment, osteopathy treatment and the like, and has good treatment effect on disease prevention and rehabilitation of patients. Can be widely applied to medical and cosmetic treatment.
After centrifugation, the blood can be separated into three layers of serum, platelet-rich plasma (PRP) and red blood cells, wherein the PRP obtained after separation has no any infection risk and anaphylactic reaction, and meanwhile, the PRP can quickly stop bleeding, relieve pain, accelerate wound healing and greatly reduce the formation of postoperative scars.
The following problems exist at the present stage: the concentration and the quality of the extracted PRP can not meet the requirements; the automation degree is low, and the waiting time is long; manually extracting visual errors of PRP; the extraction process needs manual operation; the existing method is to realize one-cavity four-tube analysis, only 2 tubes of blood with 20ml can be analyzed at each time, and the separation needs to be carried out for a plurality of times when the volume is relatively small.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a device for automatically separating and extracting PRP, which realizes mechanical automation operation and has high precision.
In order to achieve the purpose, the invention adopts the following technical scheme:
the invention provides a device for automatically separating and extracting PRP (platelet Rich plasma), which comprises a workbench, wherein a blood collection tube placing and gravity sensing device, a counterweight water injection device, a centrifugal driving device, a mechanical extraction device and an injector and needle head separation and recovery device are sequentially arranged on the workbench according to working procedures;
A first sliding rail, a second sliding rail, a first sliding rod and a second sliding rod are respectively arranged on two sides of the workbench, and the first sliding rod and the second sliding rod both span the workbench and are arranged with the first sliding rail and the second sliding rail;
a third slide rail is mounted on one side of the first slide bar, a fourth slide rail is mounted on one side of the second slide bar, a first mechanical arm is mounted on the third slide rail, and a second mechanical arm is mounted on the fourth slide rail;
the heparin tube is placed and gravity induction system is including storing the box, it divide into first memory area and second memory area to store the box, blood centrifuging tube is placed to first memory area, empty centrifuging tube is placed to the second memory area, gravity sensor is installed to the bottom in first memory area.
Further, counter weight water injection device includes the flood peak, the bottom intercommunication of flood peak has the separation test tube, the separation test tube is installed on last water test tube supporting seat, load cell is installed to the bottom of last water test tube supporting seat, the flood peak is installed in the backup pad, the backup pad is installed mutually with slip table cylinder and two pole cylinders, two pole cylinders are installed on cylinder support frame.
Further, the first mechanical arm reciprocates along the length direction of the first sliding rod through a third sliding rail, when the first mechanical arm moves to the blood sampling tube placing and gravity sensing device, the first mechanical arm clamps the empty centrifuge tube, the empty centrifuge tube is conveyed to the position below the water injection head through the third sliding rail, and water is injected until the weight of the centrifuge tube is the same as that of the blood centrifuge tube.
Furthermore, a circular hole is formed in the middle of the workbench, and the centrifugal driving device is installed in the circular hole;
centrifugal drive device includes brushless motor, brushless motor's one end is connected with the rigid coupling, brushless motor's the other end is installed on mounting plate, the rigid coupling with brushless motor phase-separated one end links to each other with the separator bracket through the rotation axis, the separator container area in control that a plurality of symmetries set up is installed all around to the separator bracket, the opto-coupler is installed to one side of rotation axis.
Further, syringe and syringe needle assembly device includes the device dish, the middle part of device dish is equipped with a plurality of syringe device districts, be equipped with a plurality of syringe needle districts around the device dish, syringe device district embeds there is the syringe, syringe needle district embeds there is the syringe needle, first motor is installed to the bottom of device dish, first motor can drive the device dish rotates.
Further, the injector device area includes a plurality of injector sleeves mounted in a middle portion of the device tray, the injectors being insertable into the injector sleeves; the injection needle head area comprises a hollow optical axis, the hollow optical axis is installed on the device disc, a compression spring is sleeved outside the hollow optical axis, and the injection needle head can be inserted into the hollow optical axis.
Further, the mechanical extraction device comprises a rear mounting plate, a sliding block is mounted on the rear mounting plate, a first ball screw is mounted at the bottom of the rear mounting plate, an injection pump extraction device is mounted at the front end of the rear mounting plate, and the injection pump extraction device is connected with the sliding block; the first stepping motor rotates to drive the first ball screw to rotate, and then drives the sliding block to move back and forth along the vertical direction, so that the injection pump pumping device is driven to move back and forth along the vertical direction.
Further, the injection pump pumping device comprises an injection bottom plate, a second ball screw is mounted on the injection bottom plate, a second driving block is mounted on the second ball screw, a second stepping motor is mounted at the top end of the second ball screw, a pneumatic finger clamp is mounted on one side of the bottom of the injection bottom plate, and the opening and closing of the pneumatic finger clamp are controlled through a finger clamp air cylinder;
The second stepping motor drives the second ball screw to rotate, and further drives the second driving block to move back and forth along the vertical direction, so that the injection pump is pressed down or pulled up.
Further, the device for separating and recovering the syringe and the needle head comprises a recovery drawer box, wherein the needle head separation box is arranged at the upper part of the recovery drawer box; a blanking placing box is inserted into the upper end of the needle head separating box in a penetrating manner, an air cylinder and an ejector rod are arranged in the needle head separating box, and the ejector rod is horizontally opposite to a blanking port of the blanking placing box; the outer wall of one side of the needle head separation box is provided with a first hole and a second hole, and the first hole and the second hole are connected through a long through groove; and a disinfection ultraviolet lamp is arranged on one side of the inner wall of the needle head separation box.
The invention has the beneficial effects that: 1) the device mainly comprises a main body, a separating device, a PRP automatic interval detection device, a PRP automatic extraction device, a four-coordinate transmission device, an injector and a needle head automatic assembly device, an injector and needle head separation and automatic capping device, a finished product storage device, a separating tube counterweight device, an induction device and the like; 2) after PRP separation, scanning in a mode that an optical image sensor moves up and down, and identifying the height of red blood cells of a separation tube so as to determine the contact height of the red blood cells and a liquid surface layer under the PRP; 3) by determining the height of the liquid level layer and calculating the actual distance from the zero point to the PRP layer by using a software algorithm, the mechanical extraction device can accurately extract the needle head of the syringe from the PRP layer; 4) identifying the weight of the blood sampling tube through the gravity sensor, determining a corresponding counter weight when the counter weight is determined, and ensuring the mutual balance of the separation tubes; 5) the whole structure layout is compact, and the whole transmission and grabbing are completed by using a manipulator;
Drawings
FIG. 1 is a schematic structural diagram of an apparatus for automatic separation and extraction of PRP according to the present invention;
FIG. 2 is a schematic view of a centrifugal driving device;
FIG. 3 is a second schematic structural view of the centrifugal driving device;
FIG. 4 is a schematic view of the syringe and needle assembly device;
FIG. 5 is a schematic view of a mechanical extraction device;
FIG. 6 is a schematic view of the syringe and needle separating and recovering device;
FIG. 7 is a second schematic view of the syringe and needle separation and recovery device;
FIG. 8 is a schematic view showing a structure of a liquid level sensor;
fig. 9 is a second schematic structural view of the liquid level sensor.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Referring to fig. 1, a device for automatically separating and extracting PRP comprises a workbench 1, wherein a blood collection tube placing and gravity sensing device 6, a counterweight water injection device 5, a centrifugal driving device 2, an injector and needle head assembling device 4, a mechanical extraction device 7 and an injector and needle head separating and recovering device 3 are sequentially arranged on the workbench 1 according to the working procedures;
A first slide rail 101, a second slide rail 102, a first slide bar 103 and a second slide bar 104 are respectively mounted on two sides of the workbench 1, and the first slide bar 103 and the second slide bar 104 are mounted with the first slide rail 101 and the second slide rail 102 across the workbench 1;
a third slide rail 1031 is mounted on one side of the first slide bar 103, a fourth slide rail 1032 is mounted on one side of the second slide bar 104, a first mechanical arm 105 is mounted on the third slide rail 1031, and a second mechanical arm 106 is mounted on the fourth slide rail 1032;
heparin tube is placed and gravity induction system 6 is including storing box 601, it divide into first memory area and second memory area to store box 601, blood centrifuging tube is placed to first memory area, empty centrifuging tube is placed to the second memory area, gravity sensor is installed to the bottom in second memory area.
Counter weight water injection device 5 includes water injection head 501, water injection head 501's bottom intercommunication has the separation test tube, the separation test tube is installed on last water test tube supporting seat, load cell is installed to the bottom of going up water test tube supporting seat, the water injection head is installed in the backup pad, the backup pad is installed mutually with slip table cylinder and two pole cylinders, two pole cylinders are installed on cylinder support frame.
The first robot arm 105 reciprocates along the length direction of the first slide bar 103 through the third slide rail 1031, when the first robot arm 105 moves to the blood sampling tube placing and gravity sensing device 6, the first robot arm 105 clamps the empty centrifuge tube, and conveys the empty centrifuge tube to the position below the water injection head 501 through the third slide rail 1031, and water is injected until the weight of the centrifuge tube is the same as that of the blood centrifuge tube.
A circular hole 107 is formed in the middle of the workbench 1, and the centrifugal driving device 2 is installed in the circular hole 107;
referring to fig. 2 and 3, the centrifugal driving device 2 includes a brushless motor 202, one end of the brushless motor 202 is connected to a rigid coupling 203, the other end of the brushless motor 202 is mounted on a mounting base plate 201, the end of the rigid coupling 203 away from the brushless motor 202 is connected to a separation frame 208 through a rotating shaft 209, a plurality of separation vessel pipe areas 207 symmetrically arranged are mounted around the separation frame 208, and an optical coupler 206 is mounted on one side of the rotating shaft 209.
Centrifugal drive device 2: the centrifugal machine is fixed on the bottom plate, and 8 damping springs are used around the centrifugal machine; the rigid coupling is connected with the motor and the rotating shaft; the upper part and the lower part of the rotating shaft are respectively kept in axial tension and balance by a tapered roller bearing; the two sides of the opposite side of the separator are respectively provided with a separating sleeve, the sleeves are provided with separating tubes and counterweight test tubes with the same weight, and the two sides of the separating sleeves are provided with grooves for scanning PRP and erythrocyte layers in the separating tubes through the movement of the sensor after the separation is finished; the separator is provided with a limit switch, and the PRP extraction separation pipe is kept in the same direction after the separation frame slowly stops rotating through program setting.
Referring to fig. 4, the injector and needle assembly device 4 includes a device tray 401, a plurality of injector device areas are disposed in the middle of the device tray 401, a plurality of needle areas are disposed around the device tray 401, an injector 411 is disposed in each injector device area, an injection needle 410 is disposed in each needle area, a first motor 402 is mounted at the bottom of the device tray 401, and the first motor 402 can drive the device tray 401 to rotate.
The injector device area includes a plurality of injector sleeves 405, the injector sleeves 405 are mounted in the middle of the device tray 401, and the injectors 411 can be inserted into the injector sleeves 405; the injection needle section comprises a hollow optical axis 406, the hollow optical axis 406 is mounted on the device disc 401, a compression spring 404 is sleeved outside the hollow optical axis 406, and the injection needle 410 can be inserted into the hollow optical axis 406.
The injector and the needle head are separately arranged before being assembled, the injector is placed in the sleeve, the injection needle head is placed in the hollow optical axis sleeve, the injector is clamped by the manipulator and then accurately inserted into the hollow sleeve, the sleeve is arranged in the linear bearing, the compression spring is arranged outside the sleeve, and the injector and the needle head can be assembled together in a rebounding process; the device is provided with a stepping motor as a driving rotating shaft to rotate, a rotary disc is provided with a limit switch, and the position of each rotating injector is kept to pause at the same position; the rotary bottom plate is provided with a protective cover, and the periphery of the rotary bottom plate is provided with disinfection ultraviolet lamps to ensure that the needle head is in a sterile environment; the rotating bottom plate is provided with an injector placing limiting cover clamping groove, so that the placing positions of the injectors can be kept consistent when the injectors are placed, and errors caused by clamping of a manipulator due to inconsistent placing directions are avoided;
Referring to fig. 5, the mechanical pumping device 7 includes a rear mounting plate 704, a sliding block 703 is mounted on the rear mounting plate 704, a first ball screw 713 is mounted at the bottom of the rear mounting plate, and a syringe pump pumping device is mounted at the front end of the rear mounting plate and connected to the sliding block 703; the first stepping motor 711 rotates to drive the first ball screw 713 to rotate, so as to drive the slider 703 to reciprocate along the vertical direction, thereby driving the injection pump pumping device to reciprocate along the vertical direction.
The injection pump extraction device comprises an injection bottom plate 714, a second ball screw 717 is installed on the injection bottom plate 714, a second driving block 710 is installed on the second ball screw 717, a second stepping motor 712 is installed on the top end of the second ball screw 717, a pneumatic finger clamp 708 is installed on one side of the bottom of the injection bottom plate 714, and the pneumatic finger clamp 708 is controlled to open and close through a finger clamp air cylinder 709.
The automatic extraction device comprises a driving part and an extraction part, wherein the driving part mainly comprises a driving motor, a ball screw, a limit switch, a linear guide rail and the like, the extraction part mainly comprises a pneumatic finger clamp, the limit switch, a positioning device and the like, the screw is driven by a program control motor after the separation of the centrifuge is completed, a screw connecting slide block drives the extraction device to move up and down, the extraction device is provided with an injector and a needle head, the tail part of the injector is arranged on a driving block, and the injector can be accurately placed in the position after the injector is clamped by a limiting adjusting ball holding manipulator, the pneumatic finger clamp can vertically clamp the injector, and the needle head of the injector can be accurately inserted into a PRP layer of a separation tube.
The second stepping motor 712 drives the second ball screw 717 to rotate, and then drives the second driving block 710 to reciprocate along the vertical direction, thereby pressing or pulling up the injection pump.
Referring to fig. 6 and 7, the syringe and needle separation and recovery device 3 includes a recovery drawer box 308, and a needle separation box is mounted on an upper portion of the recovery drawer box 308; a blanking placing box 301 is inserted into the upper end of the needle head separating box in a penetrating manner, an air cylinder 305 and an ejector rod 306 are arranged in the needle head separating box, and the ejector rod 306 is horizontally opposite to a blanking port of the blanking placing box 301; a first hole 307 and a second hole 3081 are formed in the outer wall of one side of the needle head separation box, and the first hole 307 and the second hole 3081 are connected through a long through groove 309; and a disinfection ultraviolet lamp 310 is arranged on one side of the inner wall of the needle head separation box.
The manipulator stretches into the front panel round hole draw-in groove with the syringe after extracting the PRP, extrudes the syringe needle through the wedge extrusion of last syringe needle and draw-in groove, and the syringe needle directly falls into in the recovery drawer box. The injector continuously moves upwards to the position of the upper round hole, the cylinder push rod is pushed forwards through the touch switch, and the blanking placing box is provided with the sterile cap and pushed to the head of the injector, so that the action of capping is completed.
1) The device is provided with a push-pull drawer for recovering and placing the needle head; 2) an ultraviolet lamp for disinfection is arranged in the device; 3) the blanking placing box is provided with a sterile cover cap, and the blanking placing box is superposed to facilitate free falling;
the operation process of the device for automatically separating and extracting the PRP comprises the following steps:
1) blood to be separated is placed in the blood centrifugal tube, the blood centrifugal tube is weighed, and the first mechanical arm 105 conveys the empty centrifugal tube to the counterweight water injection device 5 through the third sliding rail 1031;
2) the counterweight water injection device 5 injects water into the hollow centrifugal tube through a water injection head 501 until the weight of the hollow centrifugal tube is consistent with that of the blood centrifugal tube;
the water injection head 501 completes the up-and-down and left-and-right movement of the water injection head 501 through the sliding table cylinder 505 and the double-rod cylinder 506 so as to ensure that the water injection head 501 is just opposite to the air-entering centrifugal tube;
3) the first robot arm 105 grips the empty filled centrifugal tube, and at the same time, the first slide bar 103 moves along the length direction of the first slide rail 101 and the second slide rail 102, so that the first robot arm 105 moves to the centrifugal driving device 2, and the first robot arm 105 puts the empty filled centrifugal tube into the separation container zone 207; placing the blood centrifugal tube into the symmetrical separation container tube areas 207, and keeping the two symmetrical separation container tube areas 207 balanced and equal in weight;
4) The centrifugal driving device 2 drives the separation frame 208 to rotate through the rotation of the brushless motor 202, so that the blood in the blood centrifugal tube is separated; namely, the blood in the blood centrifugal tube is divided into a lower layer, a middle layer and an upper layer, wherein the middle layer is a layer to be taken;
referring to fig. 8 and 9, the liquid level detection sensor includes a detection cylinder 801, the detection cylinder 801 is fixed at the bottom of a fixing plate 805, a ball screw fixing seat 806 is installed at one side of the fixing plate 805, the ball screw fixing seat 806 is installed along the vertical direction, a ball screw 804 is installed on the ball screw fixing seat 806, the bottom of the ball screw 804 is connected with a detection stepping motor 802 through a coupling 803, a light source lamp 808 is installed at one side of the ball screw 804, an optical sensor 807 is installed at the other side of the ball screw 804, and the blood stratification condition in the blood centrifuge tube can be detected through the light source lamp 808 and the optical sensor 807.
5) The second slide bar 104 moves along the length direction of the first slide rail 101 and the second slide rail 102, so that the second mechanical arm 106 moves to the syringe and needle assembling device 4, the second mechanical arm extracts the syringe 411 in the syringe sleeve 405 and assembles the syringe 411 and the injection needle 410;
Rotating the first motor 402 can rotate the device disk 401, thereby rotating the syringe 411 and the injection needle 410 to the proper position;
6) the second mechanical arm 106 grips the assembled syringe 411 with the injection needle 410, moves to the mechanical extraction device 7 along the second sliding rod 104, places the assembled syringe into the pneumatic finger grip 708, inserts the injection needle 410 into the middle layer of the blood centrifuge tube, and drives the second driving block 710 to move up and down along a straight line through the second stepping motor 712, thereby completing the extraction of the second layer;
the first stepping motor 711 rotates to drive the sliding block 703 to move, so that the injection needle 410 is controlled to enter the second layer, and the position is kept accurate;
7) the finger clamp cylinder 709 controls the opening of the pneumatic finger clamp 708, the second mechanical arm 106 clamps the syringe for extracting blood and inserts the syringe into the needle separation box through the first hole 307, the second mechanical arm 106 drives the syringe to move upwards to enable the syringe to enter the long through groove, the syringe is pulled, the long through groove enables the syringe needle to be separated, the syringe continues to move upwards to reach the bottom port of the blanking placing box 301, the syringe is connected with a cap in the blanking placing box 301 by propping up the syringe to enable the syringe to be connected with the cap in the blanking placing box 301, the ejector rod 306 moves to complete the sleeving of the syringe and the cap, the syringe continues to move upwards to be drawn out from the second hole 3081, and the whole process is completed.
The above-mentioned embodiments only express the implementation manner of the present invention, and the description thereof is specific and detailed, but not to be understood as the limitation of the patent scope of the present invention. It should be noted that various changes and modifications can be made by those skilled in the art without departing from the spirit of the invention, and these changes and modifications are all within the scope of the invention. Therefore, the protection scope of the present patent should be subject to the appended claims.

Claims (4)

1. An apparatus for automatically separating and extracting PRP, comprising: the blood collection tube and gravity sensing device comprises a workbench (1), wherein a blood collection tube placing and gravity sensing device (6), a counterweight water injection device (5), a centrifugal driving device (2), an injector and needle head assembling device (4), a mechanical extracting device (7) and an injector and needle head separating and recovering device (3) are sequentially arranged on the workbench (1) according to working procedures;
a first sliding rail (101), a second sliding rail (102), a first sliding rod (103) and a second sliding rod (104) are respectively arranged on two sides of the workbench (1), and the first sliding rod (103) and the second sliding rod (104) both cross over the workbench (1) and are arranged with the first sliding rail (101) and the second sliding rail (102);
a third slide rail (1031) is mounted on one side of the first slide bar (103), a fourth slide rail (1032) is mounted on one side of the second slide bar (104), a first mechanical arm (105) is mounted on the third slide rail (1031), and a second mechanical arm (106) is mounted on the fourth slide rail (1032);
The blood collection tube placing and gravity sensing device (6) comprises a storage box (601), the storage box (601) is divided into a first storage area and a second storage area, a blood centrifuge tube is placed in the first storage area, an empty centrifuge tube is placed in the second storage area, and a gravity sensor is installed at the bottom of the first storage area;
the counter weight water injection device (5) comprises a water injection head (501), a separation test tube is communicated with the bottom end of the water injection head (501), the separation test tube is installed on a water feeding test tube supporting seat, a weighing sensor is installed at the bottom of the water feeding test tube supporting seat, the water injection head is installed on a supporting plate, the supporting plate is installed with a sliding table cylinder and a double-rod cylinder, and the double-rod cylinder is installed on a cylinder supporting frame;
the first mechanical arm (105) reciprocates along the length direction of the first slide bar (103) through a third slide rail (1031), when the first mechanical arm (105) moves to the blood sampling tube placing and gravity sensing device (6), the first mechanical arm (105) clamps the empty centrifuge tube, conveys the empty centrifuge tube to the position below the water injection head (501) through the third slide rail (1031), and injects water until the weight of the centrifuge tube is the same as that of the blood centrifuge tube;
A circular hole (107) is formed in the middle of the workbench (1), and the centrifugal driving device (2) is installed in the circular hole (107);
the centrifugal driving device (2) comprises a brushless motor (202), one end of the brushless motor (202) is connected with a rigid coupling (203), the other end of the brushless motor (202) is installed on an installation base plate (201), the end, away from the brushless motor (202), of the rigid coupling (203) is connected with a separation frame (208) through a rotating shaft (209), a plurality of separation container tube areas (207) which are symmetrically arranged are installed on the periphery of the separation frame (208), and an optical coupler (206) is installed on one side of the rotating shaft (209);
the injector and needle head assembling device (4) comprises a device disc (401), a plurality of injector device areas are arranged in the middle of the device disc (401), a plurality of injection needle head areas are arranged on the periphery of the device disc (401), an injector (411) is arranged in each injector device area, an injection needle head (410) is arranged in each injection needle head area, a first motor (402) is installed at the bottom of the device disc (401), and the first motor (402) can drive the device disc (401) to rotate;
the injector device area comprises a plurality of injector sleeves (405), the injector sleeves (405) are installed in the middle of the device tray (401), and the injectors (411) can be inserted into the injector sleeves (405); the injection needle head area comprises a hollow optical axis (406), the hollow optical axis (406) is installed on the device disc (401), a compression spring (404) is sleeved outside the hollow optical axis (406), and the injection needle head (410) can be inserted into the hollow optical axis (406).
2. The apparatus for automatic separation and extraction of PRP according to claim 1, wherein: the mechanical extraction device (7) comprises a rear mounting plate (704), a sliding block (703) is mounted on the rear mounting plate (704), a first ball screw (713) is mounted at the bottom of the rear mounting plate, an injection pump extraction device is mounted at the front end of the rear mounting plate, and the injection pump extraction device is connected with the sliding block (703); the first stepping motor (711) rotates to drive the first ball screw (713) to rotate, so as to drive the sliding block (703) to reciprocate along the vertical direction, and further drive the injection pump pumping device to reciprocate along the vertical direction.
3. The apparatus for automatic separation and extraction of PRP according to claim 2, wherein: the injection pump pumping device comprises an injection bottom plate (714), a second ball screw (717) is installed on the injection bottom plate (714), a second driving block (710) is installed on the second ball screw (717), a second stepping motor (712) is installed at the top end of the second ball screw (717), a pneumatic finger clamp (708) is installed on one side of the bottom of the injection bottom plate (714), and the opening and the closing of the pneumatic finger clamp (708) are controlled through a finger clamp air cylinder (709);
The second stepping motor (712) drives the second ball screw (717) to rotate, and then drives the second driving block (710) to reciprocate along the vertical direction, so as to press or pull up the injection pump.
4. The apparatus for automatic separation and extraction of PRP according to claim 3, wherein: the device (3) for separating and recovering the syringe and the needle comprises a recovery drawer box (308), wherein the needle separation box is arranged at the upper part of the recovery drawer box (308); a blanking placing box (301) is inserted into the upper end of the needle head separating box in a penetrating mode, an air cylinder (305) and an ejector rod (306) are arranged in the needle head separating box, and the ejector rod (306) is horizontally opposite to a blanking port of the blanking placing box (301); the outer wall of one side of the needle head separation box is provided with a first hole (307) and a second hole (3081), and the first hole (307) is connected with the second hole (3081) through a long through groove (309); and a disinfection ultraviolet lamp (310) is arranged on one side of the inner wall of the needle head separation box.
CN202011375261.3A 2020-11-30 2020-11-30 Device for automatically separating and extracting PRP (pulse repetition program) Active CN112619907B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011375261.3A CN112619907B (en) 2020-11-30 2020-11-30 Device for automatically separating and extracting PRP (pulse repetition program)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011375261.3A CN112619907B (en) 2020-11-30 2020-11-30 Device for automatically separating and extracting PRP (pulse repetition program)

Publications (2)

Publication Number Publication Date
CN112619907A CN112619907A (en) 2021-04-09
CN112619907B true CN112619907B (en) 2022-06-28

Family

ID=75306841

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011375261.3A Active CN112619907B (en) 2020-11-30 2020-11-30 Device for automatically separating and extracting PRP (pulse repetition program)

Country Status (1)

Country Link
CN (1) CN112619907B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113797389B (en) * 2021-10-09 2022-04-26 红色未来科技(北京)有限公司 Human skin beautifying and wrinkle removing filler and preparation method thereof
CN114029175A (en) * 2021-12-03 2022-02-11 康膝生物医疗(深圳)有限公司 Centrifugal machine for PRP extraction
CN114344951A (en) * 2022-01-13 2022-04-15 武汉朗克医疗器械有限公司 Full-automatic PRP separating centrifuge assembly

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007259891A (en) * 2006-03-27 2007-10-11 Kokuyo Aluminum Seisakusho:Kk Syringe needle separation apparatus
WO2014164459A2 (en) * 2013-03-11 2014-10-09 Siemens Healthcare Diagnostics, Inc. Centrifuge loading apparatus, systems, and methods
CN104634428A (en) * 2013-11-08 2015-05-20 大连民族学院 Novel electronic scale for centrifugal tube trimming
CN107966350A (en) * 2018-01-17 2018-04-27 祝凯旋 A kind of medical test solution centrifugal device
CN109174223B (en) * 2018-09-07 2023-12-12 惠州先进制造产业技术研究中心有限公司 Medical reagent blending and integrating equipment
CN209773048U (en) * 2019-04-19 2019-12-13 山东省立医院 multipurpose needle head separating box
CN110631877B (en) * 2019-10-28 2022-04-12 宁波美生医疗器材有限公司 Tripping and separating mechanism for liquid-based cell film production
CN110579389B (en) * 2019-11-08 2020-03-13 烟台艾德康生物科技有限公司 Full-automatic sample pretreatment system

Also Published As

Publication number Publication date
CN112619907A (en) 2021-04-09

Similar Documents

Publication Publication Date Title
CN112619907B (en) Device for automatically separating and extracting PRP (pulse repetition program)
CN101496725B (en) Automatic blood sampling system and blood sampling device
CN106141663B (en) Infusion apparatus assembly process
CN114747567A (en) Biological sample detects draws quick seal up system of depositing
CN214160072U (en) Chromosome harvesting equipment
CN208125471U (en) A kind of automatic liquid separation filter
CN114088958A (en) Full-automatic platelet antibody detection analyzer and use method thereof
CN106041449B (en) Dropping funnel and catheter assembling device
CN115839872B (en) Full-automatic liquid-based cell slice-making dyeing machine
CN201257182Y (en) Blood bag extrusion device
CN208559944U (en) A kind of tubulature machine with vacuum detecting
CN215865964U (en) Liquid suction and injection detection device
CN213689651U (en) Full-automatic antibody detection equipment for coronavirus
CN210982487U (en) Sampler inserting device
CN213830387U (en) Syringe and needle head assembling device of centrifugal equipment
CN113855884A (en) Full-automatic platelet-rich plasma collector
CN213825384U (en) Mechanical extraction device of centrifugal equipment
CN205940836U (en) Vein wire guide tensile testing device
CN113813474A (en) Novel coronavirus vaccine injection instrument recovery device
CN212418355U (en) Platelet-rich plasma pushing instrument
CN110279473A (en) Blood taking needle and the rear automatic separating apparatus of needle holder
CN221797521U (en) Aseptic sampling device of medicine
CN110308297A (en) A kind of sampler insertion apparatus
CN215140988U (en) Closed centrifugal sleeve device
CN219461173U (en) Sampling and inspecting device

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant