CN112617548B - Kyara extract for manufacturing latex pillow for improving sleep, preparation method and latex pillow manufactured by using Kyara extract - Google Patents
Kyara extract for manufacturing latex pillow for improving sleep, preparation method and latex pillow manufactured by using Kyara extract Download PDFInfo
- Publication number
- CN112617548B CN112617548B CN202011560318.7A CN202011560318A CN112617548B CN 112617548 B CN112617548 B CN 112617548B CN 202011560318 A CN202011560318 A CN 202011560318A CN 112617548 B CN112617548 B CN 112617548B
- Authority
- CN
- China
- Prior art keywords
- kyara
- extract
- latex pillow
- preparing
- aquilaria sinensis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47G—HOUSEHOLD OR TABLE EQUIPMENT
- A47G9/00—Bed-covers; Counterpanes; Travelling rugs; Sleeping rugs; Sleeping bags; Pillows
- A47G9/10—Pillows
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
- A61K36/835—Aquilaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
Abstract
The invention provides a Kyara extract for preparing a latex pillow for improving sleep, a preparation method and a latex pillow prepared by the Kyara extract. The extraction method provided by the invention improves the content of sesquiterpenes and chromone components in the aquilaria sinensis extract, and the prepared latex pillow can better retain effective components and flavor substances in the aquilaria sinensis, so that the prepared latex pillow can smell elegant aquilaria sinensis flavor when falling asleep, relieve fatigue, adjust emotion, improve the problems of difficulty in falling asleep and the like, improve sleep quality, bring healthy and comfortable sleep for people, and meanwhile, the aquilaria sinensis can also prevent diseases such as cardiovascular and cerebrovascular diseases and the like, and is particularly suitable for middle-aged and elderly people.
Description
Technical Field
The invention relates to the technical field of plant essential oil, in particular to a Kyara extract for manufacturing a latex pillow for improving sleep, a preparation method and a latex pillow manufactured by the extract.
Background
The latex pillow and the latex mattress are made of natural latex and foamed by a high-tech method to form a porous open type low-density material. At present, two main production processes of latex pillow products are available, one is a Telab (Talalay) method, and the other is a Dunlop (Dunlop) method. The Talalay method is produced by mixing, injection molding, and vacuum (i.e. CO flushing)2) Freezing, vulcanizing, drying and the like, and adopts a physical foaming principle (namely vacuum absorption); the Dunlop process consists of mixing, foaming, injection moulding, vulcanizing, washing, drying, etc. and adopts the principle of chemical foaming. The Dunlop method has the advantages of low cost, fast development and the like. The preparation method (CN201910277716.9) of the natural latex pillow product applied by Shanghai Tachang health science and technology Limited company can produce latex pillows at low temperature, overcomes the problems of high viscosity during prevulcanization, ripening and foaming, easy blockage of foaming machines and equipment transmission pipelines and the like in the prior art, and is convenient to add beneficial components which cannot resist high temperature in the latex production process.
Aquilaria sinensis is a wood with resin of Aquilaria (Aquilaria) of Aquilaria of Thymelaeaceae, and is a rare medicinal material and a rare spice. As a traditional famous and precious Chinese medicine in China, the traditional Chinese medicine can be used as a sedative and an analgesic, has the functions of lowering qi and warming the middle-jiao, warming the kidney and receiving qi, diminishing inflammation and sterilizing, and can be used for treating asthma, stomachache, vomiting and hiccup, abdominal distension and pain, deficiency and coldness of waist and knees, deficient constipation of large intestine, cough, rheumatism, hyperpyrexia symptoms, difficult sleep, cardiovascular and cerebrovascular diseases and the like. The Kyara is the top and most precious variety of the agilawood, has mysterious and elegant fragrance and rich oil content, has more remarkable effect and is most expensive in the market. The homemade Kyara source plant is Aquilaria sinensis (lour.) Gilg of Thymelaeaceae.
At present, the new species of aquilaria sinensis can be quickly produced after being injured, and after the aquilaria sinensis grows for 1 to 3 years, the produced aquilaria sinensis has the quality of Qinan aquilaria sinensis, the grease is rich and the fragrance is strong, the chemical components of the aquilaria sinensis are consistent with those of Qinan aquilaria sinensis, the planting period is shorter than that of the common aquilaria sinensis, the produced fragrance has the cool taste, the sweet fragrance and the flower fragrance are strong, the grease is rich, the market acceptance is very high, and the planting area is wide. In the market, new species capable of producing the Kyara are collectively called Kyara, and the produced Kyara is often called Kyara. The method is a new resource which is rich.
Disclosure of Invention
In view of the above, the invention provides a machilus aquilaria wood extract for manufacturing a latex pillow for improving sleep, a preparation method and a latex pillow manufactured by the method, and solves the above problems.
The technical scheme of the invention is realized as follows: a Kyara extract used for preparing a latex pillow for improving sleep comprises the following components: the feed comprises the following raw materials in parts by weight: 300 parts of Qinanxiang neat oil 150-.
Further, the preparation method of the aquilaria gigas extract for preparing the latex pillow for improving sleep comprises the following steps:
(1) raw material treatment: firstly, crushing the Kyara into powder, and then carrying out water jet secondary crushing;
(2) extracting by simultaneous distillation and extraction to obtain a Machilus aquilaria fraction 1, wherein the fraction is mainly sesquiterpene components easy to volatilize;
(3) adding the distilled Kyara powder into an organic solvent, heating to 70-80 ℃, performing hot reflux extraction or ultrasonic extraction at normal temperature for 1.5-3 h, filtering while hot, repeating for 3-5 times, collecting filtrate, and concentrating under reduced pressure until the specific gravity is 1.0-1.5.
(4) And (4) freezing and precipitating the concentrated solution obtained in the step (3) for 12-24h or standing at normal temperature for 7-10d, filtering the supernatant, and concentrating under reduced pressure until no organic solvent exists to obtain a Kyara lignum aquilariae fraction 2.
(5) And mixing the fraction 1 and the fraction 2 uniformly to obtain the Kyara aquilaria absolute oil.
(6) Preparing a Kyara extract emulsion: according to the weight parts, the cinchona agilawood absolute oil and the grape seed oil are mixed uniformly, and then the deionized water, the anhydrous calcium chloride, the sodium carboxymethylcellulose, the cyclodextrin and the poloxamer are added and stirred together until the mixture is mixed uniformly, so that emulsion is obtained, namely the cinchona agilawood extract.
Further, the simultaneous distillation extraction method is that the Kyara powder is extracted by a simultaneous distillation extraction device, the heating temperature is 90-100 ℃, the distillation time is 3-8 hours, the extraction solvent is n-butane, and the fraction 1 is obtained by decompression and concentration.
Further, the pressure of the water jet is 80-120 MPa.
Further, the organic solvent is an ethanol water solution, wherein the volume fraction of ethanol is 70-95%.
Further, in the process of manufacturing the latex pillow, the aquilaria sinensis extract is added after latex is well foamed, and then is uniformly stirred and manufactured according to a latex production procedure.
Furthermore, in the process of manufacturing the latex pillow, the operation is carried out at a low temperature after the aquilaria sinensis extract is added.
Further, the weight ratio of the aquilaria sinensis extract is 0.1-5%.
Compared with the prior art, the invention has the beneficial effects that:
the invention provides a preparation method of a Kyara extract and a latex pillow prepared from the Kyara extract by extracting the Kyara; according to the invention, agilawood is firstly crushed through specific process operations, and then the cell wall breaking crushing is carried out on the plants through a water jet mill, so that the solubility of agilawood fraction substances is improved, and the effective extraction of the solution of effective oily substances of agilawood in subsequent specific temperature distillation is realized; the extraction method provided by the invention can improve the content of sesquiterpene compounds and chromone compounds in the aquilaria sinensis extract, and the prepared latex pillow can better retain the active ingredients and flavor substances in the aquilaria sinensis, so that the aquilaria sinensis latex pillow prepared by the method has elegant fragrance of the aquilaria sinensis, the elegant fragrance of the aquilaria sinensis can be smelled when people fall asleep, the fatigue is relieved, the emotion is regulated, the problems of difficulty in falling asleep and the like are solved, the sleep quality is improved, healthy and comfortable sleep is brought to people, and meanwhile, the aquilaria sinensis can also prevent diseases such as cardiovascular and cerebrovascular diseases.
Detailed Description
In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.
The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.
The materials, reagents and the like used in the examples of the present invention are commercially available unless otherwise specified.
Example 1
Taking 5 kg of raw materials of the aquilaria sinensis, crushing the raw materials into powder, performing water jet crushing at the pressure of 80MPa, extracting by adopting a simultaneous distillation extraction method, heating the extraction method to 90 ℃, distilling the extraction solvent for 8 hours, and performing reduced pressure concentration to obtain 20 g of fraction 1, wherein the extraction solvent is n-butane. And adding the extracted Kyara powder into an 85% ethanol solvent, heating to 80 ℃, carrying out hot reflux extraction for 2h each time, filtering while the solution is hot, repeating for 3-5 times, collecting filtrate, controlling the temperature to be 45 ℃ and the pressure to be 100hpa, concentrating until the specific gravity of the feed liquid is 1.1, standing at normal temperature for 7 days, carrying out suction filtration on supernate, and concentrating until no organic solvent exists to obtain a fraction of 2 g and 400 g. And mixing the fraction 1 and the fraction 2 uniformly, and obtaining 420 g of the aquilaria sinensis absolute oil. And then evenly mixing the extract with 10 g of grape seed oil, and then stirring the mixture with 20 g of deionized water, 1 g of anhydrous calcium chloride, 0.2 g of sodium carboxymethylcellulose, 0.02 g of cyclodextrin and 1 g of poloxamer till even mixing to obtain emulsion, namely the aquilaria sinensis extract.
According to the latex pillow manufacturing procedure, after latex foaming is completed in sequence, according to the mass fraction of 0.1%, the Kyara extract and other raw materials are added, the mixture is uniformly stirred, and the Kyara latex pillow is manufactured according to the low-temperature manufacturing process.
Example 2
Taking 10 kg of raw materials of the aquilaria sinensis, crushing the raw materials into powder, performing water jet crushing at the pressure of 120MPa, extracting the raw materials by adopting a simultaneous distillation extraction method, heating the raw materials at the temperature of 100 ℃, distilling the raw materials for 3 hours, wherein an extraction solvent is n-butane, performing reduced pressure concentration to obtain 4 g of fraction 1, adding the extracted aquilaria sinensis powder into a 95% ethanol solvent, performing ultrasonic extraction at normal temperature for 3 hours each time, filtering, repeating the extraction for 5 times, collecting filtrate, performing reduced pressure concentration at the temperature of 45 ℃, controlling the pressure at 100hpa, concentrating the filtrate until the specific gravity of the feed liquid is 1.1, performing freezing storage for 12 hours, performing suction filtration on supernate, and concentrating the supernate until no organic solvent exists to obtain 2 g and 196 g of fraction. And mixing the fraction 1 and the fraction 2 uniformly, and obtaining 200 g of the Kyara aquilaria tree absolute oil. And then mixing with 15 g of grape seed oil, adding 80 g of deionized water, 3 g of anhydrous calcium chloride, 0.8 g of sodium carboxymethylcellulose, 1 g of cyclodextrin and 3 g of poloxamer, and stirring until the mixture is uniformly mixed to obtain emulsion, namely the aquilaria sinensis extract.
According to the latex pillow manufacturing procedure, after latex foaming is sequentially completed, the Kyara extract and other raw materials are added according to the mass fraction of 1%, the mixture is uniformly stirred, and the Kyara latex pillow is manufactured according to the low-temperature manufacturing process.
Example 3
20 kg of raw materials of the aquilaria sinensis, crushing the raw materials into powder, performing water jet crushing at the pressure of 100MPa, extracting the powder by adopting a simultaneous distillation extraction method, heating the extraction method to 90 ℃, distilling the extraction solvent to be n-butane for 2 hours, performing reduced pressure concentration to obtain 15 g of fraction 1, adding the extracted aquilaria sinensis powder into an 80% ethanol solvent, heating the extraction solvent to perform reflux extraction, heating the extraction solvent to be 75 ℃, extracting the powder for 2 hours each time, filtering the extraction solvent, repeating the extraction process for 3 times, collecting filtrate, performing reduced pressure concentration to be 45 ℃, controlling the pressure to be 100hpa, concentrating the filtrate until the specific gravity of the feed liquid is 1.3, performing refrigerated storage for 24 hours, performing suction filtration on supernatant, and concentrating the supernatant until no organic solvent exists to obtain 2 g and 358 g of fraction. And mixing the fraction 1 and the fraction 2 uniformly, and 373 g to obtain the mirabilis eaglewood absolute. And then mixing with 25 g of grape seed oil, adding 100 g of deionized water, 6 g of anhydrous calcium chloride, 1 g of sodium carboxymethylcellulose, 1 g of cyclodextrin and 7 g of poloxamer, and stirring until mixing uniformly to obtain an emulsion, namely the aquilaria sinensis extract.
According to the latex pillow manufacturing procedure, after latex foaming is completed in sequence, according to the mass fraction of 5%, the Kyara extract and other raw materials are added, the mixture is uniformly stirred, and the Kyara latex pillow is manufactured according to the low-temperature manufacturing process.
Firstly, content determination
The content of sesquiterpenes and chromones in the aquilaria sinensis extract extracted in the embodiment 1-3 is determined, and the content determination result is as follows:
the sesquiterpene determination method comprises the following steps: and (3) analyzing by gas chromatography-mass spectrometry (GC-MS) and detecting by adopting selective ions, and determining the content of the sesquiterpene compound by comparing with the peak area of a control substance.
The method for measuring the chromone compounds comprises the following steps: and (3) diluting the solution to be detected, measuring the light absorption value of the solution to be detected at 230nm, calculating the content of the total chromone compounds in the solution to be detected according to the obtained light absorption value and the standard curve and the dilution multiple, and finally calculating the content of the chromone compounds in the agilawood sample.
| Sesquiterpene compounds% | Chromone compounds% | |
| Example 1 | 58.6 | 15.46 |
| Example 2 | 50.3 | 13.27 |
| Example 3 | 53.4 | 16.35 |
Second, sensory evaluation test
Sensory evaluation tests are carried out on the sleep-aiding Kyara latex pillows obtained in the embodiments 1 to 3, and the evaluation is mainly carried out on the fragrance characteristics of the Kyara, and the fragrance characteristics mainly comprise two aspects of fragrance quality and fragrance quantity. The two aspects are scored according to the grade of 0-10, and the higher the score is, the better the aroma characteristics of the Kyara are. 100 test subjects, 50 males and 50 females, aged 25-60 years. The 100 test objects were tested by using the machilus nanensis gum latex pillows of embodiments 1-3 of the present invention, and the test objects were tested 7 days, 1 month, 2 months and 3 months after the machilus nanensis gum latex pillows of the present invention were continuously used, respectively, and the average values were obtained, and the test results are shown in table 1.
TABLE 1 sensory evaluation test for fragrance of Kyara
The experiment result proves that the Kyara latex pillow for improving sleep has better fragrance, the fragrance amount of the Kyara latex pillow is related to the quality of the Kyara extract added into the Kyara latex pillow, but the whole effect is good, and a test object is more satisfied.
PSQI value test of Pittsburgh sleep quality index
PSQI was used to assess the quality of sleep of the subject for 1 month. Consisting of 19 self-rated items and 5 other rated items, of which the 19 th self-rated item and 5 other rated items did not participate in scoring. The 18 self-rated entries constitute 7 factors: sleep quality, time to sleep, sleep time, sleep efficiency, sleep disorders, hypnotics, daytime function. Each factor is scored according to the grade of 0-3, the sum of the scores of the factors is the total score of PSQI, the total score range is 0-21, and the higher the score is, the worse the sleep quality is. The subject took 5 minutes to complete the challenge. 150 subjects, 50 males and 50 females, aged 25-60, were randomized into three groups (group A, group B and group C), with 50 subjects per group. The three groups of test subjects were tested without using the machilus nanensis gum latex pillow for improving sleep of the present invention, and the average value was taken for each group. The same test object was obtained, in group a, the agilawood latex pillows of embodiment 1 of the invention were used, in group B, the agilawood latex pillows of embodiment 2 of the invention were used, in group C, the agilawood latex pillows of embodiment 3 of the invention were used for 1 month continuously, and then the test was performed again, and the average value was obtained. Pittsburgh sleep quality index PSQI values comparative data are tested as shown in table 2.
TABLE 2 Pittsburgh sleep quality index PSQI value test chart
Experimental results prove that the Kyara latex pillow for improving sleep can reduce the PSQI value, shorten the sleep time of a test object, prolong the sleep time and improve the sleep quality.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and should not be taken as limiting the scope of the present invention, which is intended to cover any modifications, equivalents, improvements, etc. within the spirit and scope of the present invention.
Claims (6)
1. A preparation method of a Kyara extract for preparing a latex pillow for improving sleep is characterized by comprising the following steps: the method comprises the following steps:
(1) treating raw materials: firstly, crushing the Kyara into powder, and then carrying out water jet secondary crushing;
(2) extracting by simultaneous distillation and extraction to obtain a Kyara lignum distillate 1; the simultaneous distillation extraction method is characterized in that the Kyara powder is extracted by a simultaneous distillation extraction device, the heating temperature is 90-100 ℃, the distillation time is 3-8 hours, the extraction solvent is n-butane, and the fraction 1 is obtained by decompression and concentration;
(3) adding the distilled Kyara powder into an organic solvent, heating to 70-80 ℃, performing hot reflux extraction or ultrasonic extraction at normal temperature for 1.5-3 h, filtering while hot, repeating for 3-5 times, collecting filtrate, and concentrating under reduced pressure until the specific gravity is 1.0-1.5;
(4) freezing and precipitating the concentrated solution obtained in the step (3) for 12-24h or standing at normal temperature for 7-10d, filtering the supernatant, and concentrating under reduced pressure until no organic solvent exists to obtain a Kyara lignum distillate 2;
(5) mixing the fraction 1 and the fraction 2 to obtain QINANGXIANGQIJING oil;
(6) preparing a Kyara extract emulsion: mixing the QINANGJIAO absolute oil and the grapeseed oil uniformly according to the parts by weight, adding deionized water, anhydrous calcium chloride, sodium carboxymethylcellulose, cyclodextrin and poloxamer, and stirring until the mixture is uniformly mixed to obtain emulsion which is the QINANGJIAO extract;
the Kyara extract comprises the following raw materials in parts by weight: 300 parts of Qinan agilawood absolute oil 150-.
2. The preparation method of the aquilaria gigas extract for preparing the sleep improvement latex pillow as claimed in claim 1, wherein the preparation method comprises the following steps: the pressure of the water jet is 80-120 MPa.
3. The preparation method of the aquilaria gigas extract for preparing the sleep improvement latex pillow as claimed in claim 1, wherein the preparation method comprises the following steps: the organic solvent is an ethanol water solution with the volume fraction of 70-95%.
4. The method for preparing the aquilaria sinensis extract for preparing the latex pillow for improving sleep as claimed in claim 1, wherein the method comprises the following steps: and in the manufacturing process of the latex pillow, the aquilaria sinensis extract is added after latex is well foamed, and then is uniformly stirred and manufactured according to a latex production procedure.
5. The method for preparing the aquilaria sinensis extract for preparing the latex pillow for improving sleep as claimed in claim 1, wherein the method comprises the following steps: in the manufacturing process of the latex pillow, the operation is carried out at 30-40 ℃ after the aquilaria sinensis extract is added.
6. The method for preparing the aquilaria sinensis extract for preparing the latex pillow for improving sleep as claimed in claim 1, wherein the method comprises the following steps: the weight ratio of the aquilaria sinensis extract is 0.1-5%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011560318.7A CN112617548B (en) | 2020-12-25 | 2020-12-25 | Kyara extract for manufacturing latex pillow for improving sleep, preparation method and latex pillow manufactured by using Kyara extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011560318.7A CN112617548B (en) | 2020-12-25 | 2020-12-25 | Kyara extract for manufacturing latex pillow for improving sleep, preparation method and latex pillow manufactured by using Kyara extract |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112617548A CN112617548A (en) | 2021-04-09 |
| CN112617548B true CN112617548B (en) | 2022-07-15 |
Family
ID=75324984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011560318.7A Active CN112617548B (en) | 2020-12-25 | 2020-12-25 | Kyara extract for manufacturing latex pillow for improving sleep, preparation method and latex pillow manufactured by using Kyara extract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112617548B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112726267B (en) * | 2020-12-29 | 2023-03-03 | 海南娜古芳沉香科技有限公司 | Chinese art paper raw pulp with Qinan agilawood fragrance, chinese art paper and preparation method of Chinese art paper raw pulp |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102210538A (en) * | 2011-05-04 | 2011-10-12 | 惠州市欧野科技有限公司 | Eaglewood powder and latex mixed pillow and manufacturing method thereof |
| CN203234438U (en) * | 2013-01-14 | 2013-10-16 | 中山市国林沉香科学研究所 | Agilawood drug pillow with tranquilizing and excitement allaying effect |
| CN106031772A (en) * | 2015-03-17 | 2016-10-19 | 德江洋山河生物科技有限公司 | Composition having sleep improving function, and preparation method thereof |
| US10392371B2 (en) * | 2015-10-01 | 2019-08-27 | Senomyx, Inc. | Compounds useful as modulators of TRPM8 |
| CN105560612B (en) * | 2015-12-03 | 2019-10-22 | 北京中医药大学 | A kind of Lignum Aquilariae Resinatum extract, the medical composition and its use comprising it |
| CN105769709A (en) * | 2016-04-26 | 2016-07-20 | 唐文君 | Compounded agilawood extract essence |
| KR20180033038A (en) * | 2016-09-23 | 2018-04-02 | 최용희 | U-Type Pillow |
| CN108570005A (en) * | 2017-03-08 | 2018-09-25 | 刘力 | Dequalinium Chloride noval chemical compound and combinations thereof and purposes |
| CN106727937A (en) * | 2017-03-31 | 2017-05-31 | 上海世道健康科技有限公司 | It is a kind of to improve the health care of sleep Chinese medicine composition of state and preparation method thereof |
| CN208769352U (en) * | 2017-07-27 | 2019-04-23 | 河源市河绿沉香种植发展有限公司 | A kind of agalloch eaglewood medicine-filled pillow with refreshment and tranquilization effect |
| CN107746749A (en) * | 2017-09-28 | 2018-03-02 | 江永百润福天然植物科技发展有限公司 | A kind of preparation method and Lignum Aquilariae Resinatum extract from agalloch eaglewood residue production Lignum Aquilariae Resinatum extract |
| CN107981643B (en) * | 2017-12-06 | 2020-05-26 | 中国热带农业科学院农产品加工研究所 | Sleep-aiding natural latex pillow inner and preparation method thereof |
| CN109010149A (en) * | 2018-10-25 | 2018-12-18 | 海南师范大学 | A kind of agilawood essential oil toothpaste and preparation method thereof |
| CN210810295U (en) * | 2019-10-21 | 2020-06-23 | 中国热带农业科学院农产品加工研究所 | Body temperature controlled release sleeping aid agilawood pillowcase |
| CN110638279A (en) * | 2019-10-21 | 2020-01-03 | 中国热带农业科学院农产品加工研究所 | Body temperature controlled release sleep-aiding deep fragrance pillow inner pad material and preparation method thereof |
| CN111657383A (en) * | 2020-06-29 | 2020-09-15 | 深圳市天然树香科技有限公司 | Machilus thunbergii leaf substitute tea and preparation method thereof |
-
2020
- 2020-12-25 CN CN202011560318.7A patent/CN112617548B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN112617548A (en) | 2021-04-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106433986B (en) | A kind of Japan pepper essential oil and preparation method thereof | |
| CN101768514A (en) | Alhagi sparsifolia extract and preparation method and application thereof | |
| CN104694366B (en) | Rose fragrant rice arrack and making method thereof | |
| CN112842957B (en) | Kyara perfume and preparation method thereof | |
| CN112617548B (en) | Kyara extract for manufacturing latex pillow for improving sleep, preparation method and latex pillow manufactured by using Kyara extract | |
| CN106923123A (en) | A kind of mixed nuts rose defaecation beverage and preparation method thereof | |
| CN103330282B (en) | The application of oil ben in cigarette and the cigarette containing oil ben | |
| CN109609278A (en) | A kind of fritillary-loquat essence and its preparing purposes of the cigarette in quick-fried pearl | |
| CN103992913B (en) | Be rich in the production method of yellow wine of peppermint and bamboo juice | |
| CN109370866A (en) | Utilize making vinegar for olive fruit juice and olive leaf | |
| CN105838549A (en) | Brewing method of tea wine | |
| CN105647739B (en) | Health care Schisandra wine | |
| CN103504464B (en) | A kind of preparation method with the pipe tobacco of humectation antitussive action | |
| CN101263930A (en) | Manufacturing technology of Chinese medicine health-care cigarette | |
| CN106753912A (en) | A kind of shinyleaf yellowhorn oil handmade soap and preparation method thereof | |
| CN104814405A (en) | Pungent functional areca-nut food and preparation method thereof | |
| CN101322581B (en) | Mineral ether-extracted Pu'er cooked tea extract and preparation and use thereof | |
| CN104403795A (en) | Cigarette-use yellow rice wine extract preparation method, and application method of cigarette-use yellow rice wine extract in cigarette | |
| KR101126095B1 (en) | Method for manufacturing functional jujube using bioprocess and functional jujube | |
| CN109549167B (en) | Ginseng essence | |
| CN103271429B (en) | The application of moringa oleifera leaf extractive in cigarette and the cigarette containing moringa oleifera leaf extractive | |
| CN111743189A (en) | Preparation method of herbal plant solid spice for cigarettes | |
| CN105062688A (en) | Manufacturing method of lemon hydrolat and application thereof | |
| CN109260109A (en) | A kind of natural perfume material facial treatment essence liquid and preparation method thereof | |
| CN112899113B (en) | Method for rapidly obtaining mugwort juice wine based on essential oil |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |