CN112603837A - Gargle and using method thereof - Google Patents

Gargle and using method thereof Download PDF

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Publication number
CN112603837A
CN112603837A CN202011641545.2A CN202011641545A CN112603837A CN 112603837 A CN112603837 A CN 112603837A CN 202011641545 A CN202011641545 A CN 202011641545A CN 112603837 A CN112603837 A CN 112603837A
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parts
following components
antibacterial agent
hydrogen peroxide
food
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葛鑫鑫
金梦磊
胡伟
汤道芳
刘凯
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Lishui University
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Lishui University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22—Peroxides; Oxygen; Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42—Colour properties
    • A61K2800/43—Pigments; Dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/524—Preservatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions

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  • Oil, Petroleum & Natural Gas (AREA)
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Abstract

The invention relates to the technical field of oral cleaning products, and particularly relates to gargle. The gargle comprises the following components in parts by weight: 1-1.5 parts of food-grade hydrogen peroxide, 0.05-0.08 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.1 part of sorbitol, 0.03-0.1 part of sodium citrate, 0.01-0.08 part of pigment, 1-1.4 parts of biological antibacterial agent and 96-98 parts of deionized water. It can effectively kill the anaerobic bacteria and improve the symptoms of halitosis users.

Description

Gargle and using method thereof
Technical Field
The invention relates to the technical field of oral cleaning products, and particularly relates to gargle and a using method thereof.
Background
The oral odor is odor emitted from the oral cavity or other cavities filled with air, such as the nose, the sinuses and the pharynx, which seriously affects social interaction and mental health of people, and the WHO reports the oral odor as a disease and surveys the oral odor to show that the prevalence rate of the oral odor in China is 27.5 percent, and 50 percent of people in western countries has the oral odor all over the world, and local oral diseases are the main causes of the oral odor, but the oral odor is also the oral expression of certain serious systemic diseases, and some organic diseases also can cause the oral odor.
Along with the development of the current society, interpersonal communication is more close and frequent, social details are more emphasized, the influence of the halitosis problem on the social contact of people is increasingly highlighted, various epidemiological survey data at home and abroad show that a considerable proportion of adults are troubled by halitosis in the social contact process, the prevalence rate of halitosis is different from 19 to 43 percent, halitosis (halitosis) is an unpleasant smell emitted from the oral cavity, particularly the back part of the tongue, and Volatile Sulfides (VSC) mainly generated by oral cavity protein hydrolysis obligate anaerobes are caused.
The existing gargle for removing halitosis sold in the market has certain irritation to oral mucosa after use, is difficult to maintain fresh breath for a long time, has low selectivity for killing protein hydrolysis obligate anaerobic bacteria which generate VSC in oral cavity, and is easy to cause dysbacteriosis in oral cavity, for example, the gargle taking chlorhexidine as an effective component has short time for removing halitosis and has some non-negligible side effects, such as bitter taste, tooth and tongue surface coloring, even taste change and other problems caused by long-term use.
Disclosure of Invention
The invention aims to provide a gargle which can effectively kill anaerobic bacteria and improve the symptoms of halitosis users.
Another object of the invention is to provide a method for using the gargle, which is convenient and simple and can effectively kill the anaerobic bacteria.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
In a first aspect, the invention provides a gargle, which comprises the following components in parts by weight: 1-1.5 parts of food-grade hydrogen peroxide, 0.05-0.08 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.1 part of sorbitol, 0.03-0.1 part of sodium citrate, 0.01-0.08 part of pigment, 1-1.4 parts of biological antibacterial agent and 96-98 parts of deionized water.
Further, the composition comprises the following components in parts by weight: 1-1.1 parts of food-grade hydrogen peroxide, 0.05-0.06 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.07 part of sorbitol, 0.03-0.05 part of sodium citrate, 0.01-0.03 part of pigment, 1-1.4 parts of biological antibacterial agent and 96-97 parts of deionized water.
Further, the composition comprises the following components in parts by weight: 1.1 to 1.5 portions of food grade hydrogen peroxide, 0.06 to 0.15 portion of citric acid, 0.1 to 0.12 portion of peppermint oil, 0.07 to 0.1 portion of sorbitol, 0.05 to 0.1 portion of sodium citrate, 0.03 to 0.08 portion of pigment, 1 to 1.4 portions of biological antibacterial agent and 97 to 98 portions of deionized water.
Further, the paint comprises the following components in parts by weight: 1.05 parts of food-grade hydrogen peroxide, 0.05 part of citric acid, 0.1 part of peppermint oil, 0.05 part of sorbitol, 0.03 part of sodium citrate, 0.01 part of pigment, 1 part of biological antibacterial agent and 96.66 parts of deionized water.
Further, the composition comprises the following components in parts by weight: 1.1 parts of food-grade hydrogen peroxide, 0.06 part of citric acid, 0.1 part of peppermint oil, 0.07 part of sorbitol, 0.05 part of sodium citrate, 0.03 part of pigment, 1 part of biological antibacterial agent and 97 parts of deionized water.
Further, the composition comprises the following components in parts by weight: 1.5 parts of food-grade hydrogen peroxide, 0.08 part of citric acid, 0.15 part of peppermint oil, 0.1 part of sorbitol, 0.1 part of sodium citrate, 0.08 part of pigment, 1.4 parts of biological antibacterial agent and 98 parts of deionized water.
Further, the biological antibacterial agent comprises the following components: naringin, glycyrrhizin and vanillin.
Further, the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
Further, the food-grade hydrogen peroxide is purified by a rectification method.
In a second aspect, the invention provides a method of using the collutory as described above, by gargling or drum rinsing 5-10ml of the collutory before brushing the teeth in the morning and evening for 0.5-3 minutes, one to three days per week.
The gargle and the preparation method thereof provided by the embodiment of the invention have at least the following advantages or beneficial effects:
aiming at the first aspect, the gargle can effectively kill the protein hydrolysis obligate anaerobe which generates halitosis in the oral cavity, oxygen and foam generated in the sterilization process can destroy the hypoxia environment in the oral cavity, inhibit the reproduction of the protein hydrolysis obligate anaerobe, can also accelerate the saliva flow rate of the oral cavity, accelerate the removal of metabolites in the oral cavity and substances generated by putrefaction, and when the gargle containing food-grade hydrogen peroxide is used for treating halitosis, not only can effectively treat the halitosis of a patient, but also can slow down the generation and development of periodontal diseases of the patient to a certain extent. .
In a second aspect, the invention provides a method of using the gargle as described above, by gargling or drum rinsing 5-10ml of the gargle for 0.5-3 minutes before brushing the teeth in the morning and evening, one to three days per week. The application method is simple, and the drug effect can be improved to the best. .
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
The embodiment of the application provides a first aspect, and the invention provides an oral rinse solution which comprises the following components in parts by weight: 1-1.5 parts of food-grade hydrogen peroxide, 0.05-0.08 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.1 part of sorbitol, 0.03-0.1 part of sodium citrate, 0.01-0.08 part of pigment, 1-1.4 parts of biological antibacterial agent and 96-98 parts of deionized water.
The peppermint oil in the embodiment has the effects of resisting inflammation, easing pain and resisting bacteria, can promote penetration, changes the permeability of stratum corneum, reduces the resistance of the medicine to permeation through the skin, and improves the diffusion coefficient of the medicine in the stratum corneum of the skin; sorbitol is a sweetener, so that the mouth feel of the gargle can be improved, and the bitter taste of the food-grade hydrogen peroxide can be covered; the sodium chloride is a salty agent, and the salty gargle has a fresh salty, sweet and fresh taste, so that the cool and fresh feeling is particularly enhanced; the pigment is a colorant and can keep the inherent color of the raw materials; the color of natural substances is simulated, so that the color and the flavor are kept consistent; the product color tone can be enhanced and the psychological consciousness of consumers can be satisfied. The use of pigment in the gargle can improve the sensory properties of the paste, and the trace pigment is used to adjust the original color of the medicine, thereby achieving the effect of vision evasion; citric acid can inhibit gargle microorganism (non-anaerobic bacteria) from breeding, and has antiseptic effect; the sodium citrate can clean tongue surface, remove dental stain, stimulate or promote saliva secretion, inhibit pathogenic bacteria of halitosis, and reduce or inhibit the emission of unpleasant odor.
Various components in the gargle are compatible, the synergistic effect is achieved, the protein hydrolysis obligate anaerobe capable of effectively killing halitosis in the oral cavity can destroy the hypoxia environment in the oral cavity, the reproduction of the protein hydrolysis obligate anaerobe is inhibited, the saliva flow rate of the oral cavity can be accelerated, the substances generated by metabolites in the oral cavity and the putrefaction effect are accelerated, when the gargle containing food-grade hydrogen peroxide is used for treating halitosis, the halitosis of a patient can be effectively treated, and the generation and the development of periodontal diseases of the patient can be slowed down to a certain extent.
Further, the composition comprises the following components in parts by weight: 1-1.1 parts of food-grade hydrogen peroxide, 0.05-0.06 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.07 part of sorbitol, 0.03-0.05 part of sodium citrate, 0.01-0.03 part of pigment, 0.05-0.9 part of stevioside, 1-1.4 parts of biological antibacterial agent and 96-97 parts of deionized water.
Further, the composition comprises the following components in parts by weight: 1.1 to 1.5 portions of food grade hydrogen peroxide, 0.06 to 0.15 portion of citric acid, 0.1 to 0.12 portion of peppermint oil, 0.07 to 0.1 portion of sorbitol, 0.05 to 0.1 portion of sodium citrate, 0.03 to 0.08 portion of pigment, 0.09 to 0.1 portion of stevioside, 1 to 1.4 portions of biological antibacterial agent and 97 to 98 portions of deionized water.
Further, the paint comprises the following components in parts by weight: 1.05 parts of food-grade hydrogen peroxide, 0.05 part of citric acid, 0.1 part of peppermint oil, 0.05 part of sorbitol, 0.03 part of sodium citrate, 0.01 part of pigment, 0.05 part of stevioside, 1 part of biological antibacterial agent and 96.66 parts of deionized water.
Further, the composition comprises the following components in parts by weight: 1.1 parts of food-grade hydrogen peroxide, 0.06 part of citric acid, 0.1 part of peppermint oil, 0.07 part of sorbitol, 0.05 part of sodium citrate, 0.03 part of pigment, 0.09 part of stevioside, 1 part of biological antibacterial agent and 97 parts of deionized water.
Further, the composition comprises the following components in parts by weight: 1.5 parts of food-grade hydrogen peroxide, 0.08 part of citric acid, 0.15 part of peppermint oil, 0.1 part of sorbitol, 0.1 part of sodium citrate, 0.08 part of pigment, 0.1 part of stevioside, 1.4 parts of biological antibacterial agent and 98 parts of deionized water.
Further, the biological antibacterial agent comprises the following components: naringin, glycyrrhizin and vanillin.
Further, the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
Further, the food-grade hydrogen peroxide is purified by a rectification method.
Hydrogen peroxide is evaporated twice and diluted to 20 percent of hydrogen peroxide and water vapor, the hydrogen peroxide and the water vapor are sent into a rectifying tower, pure water is used as rectifying liquid under the pressure of 8kPa, the temperature of the bottom of the tower is controlled at 54 ℃, 50 percent of hydrogen peroxide solution is prepared, and organic impurities in the solution are removed at the same time, so that the food grade hydrogen peroxide is obtained.
In a second aspect, the invention provides a method of using the collutory as described above, by gargling or drum rinsing 5-10ml of the collutory before brushing the teeth in the morning and evening for 0.5-3 minutes, one to three days per week. The application method is simple, and the drug effect can be improved to the best.
Example 1
The embodiment provides a gargle, which comprises the following components in parts by weight: 1-1.5 parts of food-grade hydrogen peroxide, 0.05-0.08 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.1 part of sorbitol, 0.03-0.1 part of sodium citrate, 0.01-0.08 part of pigment, 1-1.4 parts of biological antibacterial agent and 96-98 parts of deionized water; the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
Example 2
The embodiment provides a gargle, which comprises the following components in parts by weight: 1-1.1 parts of food-grade hydrogen peroxide, 0.05-0.06 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.07 part of sorbitol, 0.03-0.05 part of sodium citrate, 0.01-0.03 part of pigment, 1-1.4 parts of biological antibacterial agent and 96-97 parts of deionized water; the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
Example 3
The embodiment provides a gargle, which comprises the following components in parts by weight: 1.1-1.5 parts of food-grade hydrogen peroxide, 0.06-0.15 part of citric acid, 0.1-0.12 part of peppermint oil, 0.07-0.1 part of sorbitol, 0.05-0.1 part of sodium citrate, 0.03-0.08 part of pigment, 1-1.4 parts of biological antibacterial agent and 97-98 parts of deionized water; the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
Example 4
The embodiment provides a gargle, which comprises the following components in parts by weight: 1.05 parts of food-grade hydrogen peroxide, 0.05 part of citric acid, 0.1 part of peppermint oil, 0.05 part of sorbitol, 0.03 part of sodium citrate, 0.01 part of pigment, 0.05 part of stevioside, 1 part of biological antibacterial agent and 96.66 parts of deionized water; the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
Example 5
The embodiment provides a gargle, which comprises the following components in parts by weight: 1.1 parts of food-grade hydrogen peroxide, 0.06 part of citric acid, 0.1 part of peppermint oil, 0.07 part of sorbitol, 0.05 part of sodium citrate, 0.03 part of pigment, 1 part of biological antibacterial agent and 97 parts of deionized water; the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
Example 6
The embodiment provides a gargle, which comprises the following components in parts by weight: 1.5 parts of food-grade hydrogen peroxide, 0.08 part of citric acid, 0.15 part of peppermint oil, 0.1 part of sorbitol, 0.1 part of sodium citrate, 0.08 part of pigment, 1.4 parts of biological antibacterial agent and 98 parts of deionized water; the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
Test example 6
The inventor and 2019, 12 months to 2020, 11 months collect 100 volunteers, 50 and 100 volunteers of men and women respectively suffer from halitosis caused by Volatile Sulfide (VSC) produced by oral cavity protein hydrolysis obligate anaerobe.
The 100 volunteers were divided into A, B groups, A, B groups were 25 male patients and 25 female patients, respectively, and group A used the saliva in the New tea of Kaoyoujie shellfish teeth, and group B used the saliva in example 1. The results of use are shown in table 1:
TABLE 1
Time Group A Group B
One week No obvious phenomenon Slightly improved but still having peculiar smell
Two weeks Slightly improved but still having peculiar smell Good turning and slight peculiar smell
Three weeks Slightly improved but still having peculiar smell Good turning and almost no peculiar smell
All around Good for life and containing peculiar smell Complete recovery
In conclusion: the gargle can effectively kill the protein hydrolysis obligate anaerobe generating halitosis in the oral cavity, and oxygen and foam generated in the sterilization process can destroy the hypoxia environment in the oral cavity, inhibit the reproduction of the protein hydrolysis obligate anaerobe, can also accelerate the saliva flow rate of the oral cavity, accelerate the removal of metabolites in the oral cavity and substances generated by putrefaction, when the gargle containing food-grade hydrogen peroxide is used for treating halitosis, not only can the halitosis of a patient be effectively treated, but also the generation and the development of periodontal diseases of the patient can be slowed down to a certain extent.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (10)

1. The gargle is characterized in that: the paint comprises the following components in parts by weight: 1-1.5 parts of food-grade hydrogen peroxide, 0.05-0.08 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.1 part of sorbitol, 0.03-0.1 part of sodium citrate, 0.01-0.08 part of pigment, 1-1.4 parts of biological antibacterial agent and 96-98 parts of deionized water.
2. The mouthrinse of claim 1, wherein: the paint comprises the following components in parts by weight: 1-1.1 parts of food-grade hydrogen peroxide, 0.05-0.06 part of citric acid, 0.1-0.15 part of peppermint oil, 0.05-0.07 part of sorbitol, 0.03-0.05 part of sodium citrate, 0.01-0.03 part of pigment, 1-1.4 parts of biological antibacterial agent and 96-97 parts of deionized water.
3. The mouthrinse of claim 1, wherein: the paint comprises the following components in parts by weight: 1.1 to 1.5 portions of food grade hydrogen peroxide, 0.06 to 0.15 portion of citric acid, 0.1 to 0.12 portion of peppermint oil, 0.07 to 0.1 portion of sorbitol, 0.05 to 0.1 portion of sodium citrate, 0.03 to 0.08 portion of pigment, 1 to 1.4 portions of biological antibacterial agent and 97 to 98 portions of deionized water.
4. The mouthrinse of claim 1, wherein: the paint comprises the following components in parts by weight: 1.05 parts of food-grade hydrogen peroxide, 0.05 part of citric acid, 0.1 part of peppermint oil, 0.05 part of sorbitol, 0.03 part of sodium citrate, 0.01 part of pigment, 1 part of biological antibacterial agent and 96.66 parts of deionized water.
5. The mouthrinse of claim 1, wherein: the paint comprises the following components in parts by weight: 1.1 parts of food-grade hydrogen peroxide, 0.06 part of citric acid, 0.1 part of peppermint oil, 0.07 part of sorbitol, 0.05 part of sodium citrate, 0.03 part of pigment, 1 part of biological antibacterial agent and 97 parts of deionized water.
6. The mouthrinse of claim 1, wherein: the paint comprises the following components in parts by weight: 1.5 parts of food-grade hydrogen peroxide, 0.08 part of citric acid, 0.15 part of peppermint oil, 0.1 part of sorbitol, 0.1 part of sodium citrate, 0.08 part of pigment, 1.4 parts of biological antibacterial agent and 98 parts of deionized water.
7. The mouthrinse of claim 1, wherein: the biological antibacterial agent comprises the following components: naringin, glycyrrhizin and vanillin.
8. The mouthrinse of claim 7, wherein: the biological antibacterial agent comprises the following components in parts by weight: 58-62 parts of naringin, 18-22 parts of glycyrrhizin and 18-22 parts of vanillin.
9. The mouthrinse of claim 1, wherein: the food-grade hydrogen peroxide is purified by a rectification method.
10. A method of using the gargle of any of claims 1-9, wherein: collecting 5-10ml of the collutory, gargling or drum rinsing for 0.5-3 min before brushing teeth in the morning and evening, and using for one to three days per week.
CN202011641545.2A 2020-12-31 2020-12-31 Gargle and using method thereof Pending CN112603837A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829027A (en) * 2010-05-11 2010-09-15 李少君 Multifunctional gargle and its preparation method
CN103479547A (en) * 2013-09-11 2014-01-01 上海方木精细化工有限公司 Lemon gargle
CN103479546A (en) * 2013-09-11 2014-01-01 上海方木精细化工有限公司 Cool peppermint mouthrinse solution
CN105147540A (en) * 2015-08-07 2015-12-16 苏州云舒新材料科技有限公司 Deodorizing and sterilizing collutory and preparation method thereof
CN109316370A (en) * 2017-07-31 2019-02-12 蔡银中 A kind of Chinese medicine periodontitis gargle

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829027A (en) * 2010-05-11 2010-09-15 李少君 Multifunctional gargle and its preparation method
CN103479547A (en) * 2013-09-11 2014-01-01 上海方木精细化工有限公司 Lemon gargle
CN103479546A (en) * 2013-09-11 2014-01-01 上海方木精细化工有限公司 Cool peppermint mouthrinse solution
CN105147540A (en) * 2015-08-07 2015-12-16 苏州云舒新材料科技有限公司 Deodorizing and sterilizing collutory and preparation method thereof
CN109316370A (en) * 2017-07-31 2019-02-12 蔡银中 A kind of Chinese medicine periodontitis gargle

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Application publication date: 20210406