CN112494615A

CN112494615A - Traditional Chinese medicine composition, preparation method thereof, oral medicament and application

Info

Publication number: CN112494615A
Application number: CN202011519657.0A
Authority: CN
Inventors: 姜良珍
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-12-21
Filing date: 2020-12-21
Publication date: 2021-03-16

Abstract

The invention relates to the field of medicines, and particularly discloses a traditional Chinese medicine composition and a preparation method, an oral medicament and application thereof, wherein the traditional Chinese medicine composition comprises the following raw materials: peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rheum officinale, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus mongholicus, salvia miltiorrhiza and liquorice. The traditional Chinese medicine composition prepared by the embodiment of the invention can effectively cure the helicobacter pylori disease, can obviously improve the cure rate, has short treatment time and low cost, and can play the effects of effectively treating the helicobacter pylori, reducing the occurrence of cancer and enhancing the immune function and disease resistance of the organism of a patient through the reasonable compatibility of various traditional Chinese medicines; moreover, the traditional Chinese medicine composition has the advantages of no toxic or side effect, is simple in preparation method, solves the problems of low treatment effective rate and long treatment time of the existing helicobacter pylori treatment method, and has wide market prospect.

Description

Traditional Chinese medicine composition, preparation method thereof, oral medicament and application

Technical Field

The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition, a preparation method, an oral medicament and application thereof.

Background

With the continuous development of society, people are increasingly concerned about preventing and controlling gastric cancer. Helicobacter pylori (helicobacter pylori) disease is a serious disease caused by helicobacter pylori and affecting the health of people. The early discovery of helicobacter pylori infected people can kill helicobacter pylori in time and effectively, and has great significance for preventing and controlling gastric cancer.

The helicobacter pylori diseases include gastritis, peptic ulcer, lymphoproliferative gastric lymphoma, etc. caused by helicobacter pylori infection. The proportion of people infected with H.pylori is generally 40% -70% in developing countries, and 15% -35% in developed countries. The development of the disease seriously hinders the health of people, reduces the body resistance, and slowly causes chronic gastritis, acute gastritis, gastrointestinal ulcers, peptic ulcers and gastric mucosa-associated tissue lymphoma. After helicobacter pylori infection, especially duodenal bulbar ulcer, the infection rate is about more than 90 percent, if the annual recurrence rate is about 50 percent without eradication, and the annual recurrence rate is reduced to 5 percent after the helicobacter pylori is eradicated.

Currently, the existing helicobacter pylori treatment technologies are mainly triple therapy and quadruple therapy in western medicine, but the technical scheme has the following defects in practical use: the existing helicobacter pylori treatment methods mostly adopt western medicines, but the effects are not ideal, the cure time is long, some patients cannot take the effect at all, and the possibility of relapse after cure exists, so that great pain is brought to the patients.

Disclosure of Invention

The embodiment of the invention aims to provide a traditional Chinese medicine composition to solve the problems of low treatment efficiency and long treatment time of the existing helicobacter pylori treatment method in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

a traditional Chinese medicine composition comprises the following raw materials: peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rheum officinale, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus mongholicus, salvia miltiorrhiza and liquorice.

The peach kernel, the cordyceps sinensis, the gardenia, the angelica sinensis, the crab shell, the calcined gypsum, the rhizoma anemarrhenae, the medicated leaven, the malt, the mirabilite, the rheum officinale, the upper shell, the lower shell, the safflower, the trichosanthes root, the propolis, the astragalus membranaceus, the salvia miltiorrhiza and the liquorice are all traditional Chinese medicine names, for example, the calcined gypsum, the traditional Chinese medicine name is composed of anhydrous calcium sulfate. The calcined gypsum is white powder or loose block, and the surface of the calcined gypsum is reddish and opaque; light weight, soft, fragile, powder-like, odorless, and light taste. Gypsum Fibrosum Preparatum has effects of eliminating dampness, promoting granulation, healing sore, and stopping bleeding; it is used externally to treat ulcer, eczema, scald, traumatic hemorrhage, etc. Medicated leaven, named as Chinese medicine, is prepared by fermenting herba Polygoni Hydropiperis, herba Artemisiae Annuae, semen Armeniacae amarum paste, semen Phaseoli, and fresh herba Xanthii with flour or testa Tritici. The upper and lower nails are the dorsal and ventral nails of the tortoise; the upper part of the body is the liver and kidney channel, and has the functions of nourishing yin, suppressing yang, softening hardness, dissipating stagnation, allaying fever and removing dampness; the lower part of the body has the functions of nourishing kidney, subduing yang, and eliminating deficiency heat, and the two parts are often used together.

As a further scheme of the invention: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 1-20 parts of peach kernel, 1-20 parts of cordyceps sinensis, 1-20 parts of cape jasmine, 1-20 parts of angelica sinensis, 1-20 parts of crab shell, 1-20 parts of calcined gypsum, 1-20 parts of rhizoma anemarrhenae, 1-20 parts of medicated leaven, 1-20 parts of malt, 1-20 parts of mirabilite, 1-20 parts of rheum officinale, 1-20 parts of upper shell, 1-20 parts of lower shell, 1-20 parts of safflower, 1-20 parts of trichosanthes root, 1-20 parts of propolis, 1-20 parts of astragalus membranaceus, 1-20 parts of salvia miltiorrhiza and 1-20 parts of liquorice.

As a further scheme of the invention: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 2-10 parts of peach kernel, 2-10 parts of cordyceps sinensis, 2-10 parts of cape jasmine, 2-10 parts of angelica sinensis, 2-10 parts of crab shell, 2-10 parts of calcined gypsum, 2-10 parts of rhizoma anemarrhenae, 2-10 parts of medicated leaven, 2-10 parts of malt, 2-10 parts of mirabilite, 2-10 parts of rheum officinale, 2-10 parts of upper shell, 2-10 parts of lower shell, 2-10 parts of safflower, 2-10 parts of trichosanthes root, 2-10 parts of propolis, 2-10 parts of astragalus membranaceus, 2-10 parts of salvia miltiorrhiza and 2-10 parts of liquorice.

As a still further scheme of the invention: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 4-6 parts of peach kernel, 4-6 parts of cordyceps sinensis, 4-6 parts of cape jasmine, 4-6 parts of angelica sinensis, 4-6 parts of crab shell, 4-6 parts of calcined gypsum, 4-6 parts of rhizoma anemarrhenae, 4-6 parts of medicated leaven, 4-6 parts of malt, 4-6 parts of mirabilite, 4-6 parts of rheum officinale, 4-6 parts of upper shell, 4-6 parts of lower shell, 4-6 parts of safflower, 4-6 parts of trichosanthes root, 4-6 parts of propolis, 4-6 parts of astragalus membranaceus, 4-6 parts of salvia miltiorrhiza and 4-6 parts of liquorice.

As a still further scheme of the invention: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 5 parts of peach kernel, 5 parts of cordyceps sinensis, 5 parts of cape jasmine, 5 parts of angelica sinensis, 5 parts of crab shell, 5 parts of calcined gypsum, 5 parts of rhizoma anemarrhenae, 5 parts of medicated leaven, 5 parts of malt, 5 parts of mirabilite, 5 parts of rheum officinale, 5 parts of upper shell, 5 parts of lower shell, 5 parts of safflower, 5 parts of trichosanthes root, 5 parts of propolis, 5 parts of astragalus membranaceus, 5 parts of salvia miltiorrhiza and 5 parts of liquorice.

Another object of the embodiments of the present invention is to provide a method for preparing a Chinese medicinal composition, which comprises the following steps:

weighing peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rheum officinale, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus mongholicus, salvia miltiorrhiza and liquorice according to the parts by weight, uniformly mixing, crushing and extracting to obtain the traditional Chinese medicine composition.

As a still further scheme of the invention: the preparation method of the traditional Chinese medicine composition also comprises the step of cleaning peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rheum officinale, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus, salvia miltiorrhiza and liquorice before mixing.

As a still further scheme of the invention: the water used for washing may be any one selected from purified water, mineral water, distilled water, deionized water, and soft water, and is not limited herein and may be selected as needed.

As a still further scheme of the invention: in the preparation method of the traditional Chinese medicine composition, the extraction is a traditional Chinese medicine composition prepared by extracting and extracting a plurality of traditional Chinese medicine powders. The preferable scheme is that the capsule is prepared by cleaning and smashing five parts of each of peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rheum officinale, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus membranaceus, salvia miltiorrhiza and liquorice, extracting and preparing the capsules with the weight of 0.5g per capsule.

Another object of the embodiments of the present invention is to provide a Chinese medicinal composition prepared by the above preparation method.

Another object of the embodiments of the present invention is to provide an application of the Chinese medicinal composition in preparing a medicament for treating helicobacter pylori.

Another objective of the embodiments of the present invention is to provide an oral pharmaceutical preparation, which comprises a part or all of the above-mentioned Chinese medicinal composition.

As a still further scheme of the invention: the dosage form of the oral medicament is capsules, pills or decoction.

Preferably, the dosage form of the oral medicament can be a capsule.

As a still further scheme of the invention: the preparation method of the oral medicament is that when the dosage form of the oral medicament is a capsule, the existing capsule preparation method is adopted, and the oral medicament is obtained by adding conventional auxiliary materials into the traditional Chinese medicine composition and then packaging the traditional Chinese medicine composition by a capsule shell; the addition amount of the auxiliary materials is not limited, and the auxiliary materials can be added according to the addition amount in the prior art.

As a still further scheme of the invention: when the dosage form of the oral medicament is a capsule, the oral medicament can be prepared into capsules of 0.2-0.8g (preferably 0.5g) per granule, and the using method of the oral medicament is as follows: the helicobacter pylori can be cured after the drug is taken for one to two weeks for patients with helicobacter pylori. The adult takes the medicine twice a day, three to five pills each time, and the children take the medicine once to two times a day, one to two pills each time, and the medicine needs to be flexibly mastered according to the illness state and physical condition of the patients.

Another object of the embodiments of the present invention is to provide an application of the oral pharmaceutical preparation in preparing a medicament for treating helicobacter pylori disease.

Compared with the prior art, the invention has the beneficial effects that:

the traditional Chinese medicine composition prepared by the embodiment of the invention can effectively cure the helicobacter pylori disease, can obviously improve the cure rate, has short treatment time and low cost, and can play the effects of effectively treating the helicobacter pylori, reducing the occurrence of cancer and enhancing the immunologic function and disease resistance of a patient body through the reasonable compatibility of Chinese herbal medicines such as peach kernel, cordyceps sinensis, gardenia, angelica, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rhubarb, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus, salvia miltiorrhiza and liquorice; moreover, the traditional Chinese medicine composition provided by the invention has the advantages of no toxic or side effect due to the adoption of the Chinese herbal medicine raw materials, is simple in preparation method, solves the problems of low treatment effective rate and long treatment time of the existing helicobacter pylori treatment method, and has wide market prospect.

Detailed Description

The present invention will be described in further detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. All falling within the scope of the present invention.

Example 1

A capsule (specifically pylorus restoration capsule) comprises the following raw materials: peach kernel, Chinese caterpillar fungus, cape jasmine, Chinese angelica, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rhubarb, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus, salvia miltiorrhiza and liquorice, wherein each of the Chinese medicines is 5 g.

In this example, the preparation method of the capsule is as follows:

1) weighing the above peach kernels, cordyceps sinensis, gardenia, angelica sinensis, crab shells, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rheum officinale, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus membranaceus, salvia miltiorrhiza and liquorice, uniformly mixing, crushing and extracting effective components to obtain the traditional Chinese medicine composition;

2) conventional auxiliary materials are added into the traditional Chinese medicine composition, and then the traditional Chinese medicine composition is packaged by a capsule shell to prepare capsules of 0.5g per capsule as oral medicaments.

In this example, the capsule prepared with 0.5g per capsule can be cured by being administered to a patient suffering from helicobacter pylori for a period of one to two weeks. The adult takes the medicine twice a day, three to five pills each time, and the children take the medicine once to two times a day, one to two pills each time, and the medicine needs to be flexibly mastered according to the illness state and physical condition of the patients.

Example 2

A traditional Chinese medicine composition comprises the following raw materials: 1g of peach kernel, 1g of cordyceps sinensis, 1g of cape jasmine, 1g of angelica sinensis, 1g of crab shell, 1g of calcined gypsum, 1g of rhizoma anemarrhenae, 1g of medicated leaven, 1g of malt, 1g of mirabilite, 1g of rheum officinale, 1g of upper shell, 1g of lower shell, 1g of safflower, 1g of trichosanthes root, 1g of propolis, 1g of astragalus membranaceus, 1g of salvia miltiorrhiza and 1g of liquorice.

In this embodiment, the preparation method of the Chinese medicinal composition is as follows:

weighing the above peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rhubarb, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus, salvia miltiorrhiza and liquorice, cleaning the peach kernel, the cordyceps sinensis, the gardenia, the angelica sinensis, the crab shell, the calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rhubarb, the upper shell, the lower shell, the safflower, the trichosanthes root, the propolis, the astragalus, the salvia miltiorrhiza and the liquorice, then uniformly mixing, and extracting effective components after crushing to obtain the traditional Chinese medicine composition.

Example 3

A traditional Chinese medicine composition comprises the following raw materials: 1g of peach kernel, 1g of cordyceps sinensis, 1g of cape jasmine, 1g of angelica sinensis, 1g of crab shell, 1g of calcined gypsum, 1g of rhizoma anemarrhenae, 1g of medicated leaven, 1g of malt, 1g of mirabilite, 1g of rheum officinale, 1g of upper shell, 1g of lower shell, 1g of safflower, 1g of trichosanthes root, 20g of propolis, 20g of astragalus membranaceus, 20g of salvia miltiorrhiza and 20g of liquorice.

Example 4

A traditional Chinese medicine composition comprises the following raw materials: 20g of peach kernel, 20g of cordyceps sinensis, 20g of cape jasmine, 20g of angelica sinensis, 20g of crab shell, 20g of calcined gypsum, 20g of rhizoma anemarrhenae, 20g of medicated leaven, 20g of malt, 20g of mirabilite, 20g of rheum officinale, 20g of upper shell, 20g of lower shell, 20g of safflower, 20g of trichosanthes root, 20g of propolis, 20g of astragalus membranaceus, 20g of salvia miltiorrhiza and 20g of liquorice.

Example 5

A traditional Chinese medicine composition comprises the following raw materials: 15g of peach kernel, 15g of cordyceps sinensis, 15g of cape jasmine, 15g of Chinese angelica, 15g of crab shell, 15g of calcined gypsum, 15g of rhizoma anemarrhenae, 15g of medicated leaven, 15g of malt, 15g of mirabilite, 15g of rheum officinale, 15g of upper shell, 15g of lower shell, 15g of safflower, 15g of trichosanthes root, 15g of propolis, 15g of astragalus membranaceus, 15g of salvia miltiorrhiza and 15g of liquorice.

Example 6

Compared to example 1, except that the starting materials included: 2g of peach kernel, 2g of cordyceps sinensis, 2g of cape jasmine, 2g of angelica sinensis, 2g of crab shell, 2g of calcined gypsum, 2g of rhizoma anemarrhenae, 2g of medicated leaven, 2g of malt, 2g of mirabilite, 2g of rheum officinale, 2g of upper shell, 2g of lower shell, 2g of safflower, 2g of trichosanthes root, 2g of propolis, 2g of astragalus membranaceus, 2g of salvia miltiorrhiza and 2g of liquorice. The rest is the same as in example 1.

Example 7

Compared to example 1, except that the starting materials included: 4g of peach kernel, 4g of cordyceps sinensis, 4g of cape jasmine fruit, 4g of Chinese angelica, 4g of crab shell, 4g of calcined gypsum, 4g of rhizoma anemarrhenae, 4g of medicated leaven, 4g of malt, 4g of mirabilite, 4g of rheum officinale, 4g of upper shell, 8g of lower shell, 8g of safflower, 8g of trichosanthes root, 8g of propolis, 8g of astragalus mongholicus, 8g of salvia miltiorrhiza and 8g of liquorice. The rest is the same as in example 1.

Example 8

Compared to example 1, except that the starting materials included: 7g of peach kernel, 7g of cordyceps sinensis, 7g of cape jasmine fruit, 7g of Chinese angelica, 7g of crab shell, 7g of calcined gypsum, 7g of rhizoma anemarrhenae, 7g of medicated leaven, 7g of malt, 7g of mirabilite, 7g of rheum officinale, 7g of upper shell, 10g of lower shell, 10g of safflower, 10g of trichosanthes root, 10g of propolis, 10g of astragalus membranaceus, 10g of salvia miltiorrhiza and 10g of liquorice. The rest is the same as in example 1.

Example 9

Compared to example 1, except that the starting materials included: 4g of peach kernel, 4g of cordyceps sinensis, 4g of cape jasmine fruit, 4g of Chinese angelica, 4g of crab shell, 4g of calcined gypsum, 4g of rhizoma anemarrhenae, 4g of medicated leaven, 4g of malt, 4g of mirabilite, 4g of rheum officinale, 4g of upper shell, 4g of lower shell, 4g of safflower, 4g of trichosanthes root, 6g of propolis, 6g of astragalus mongholicus, 6g of salvia miltiorrhiza and 6g of liquorice. The rest is the same as in example 1.

Example 10

Compared to example 1, except that the starting materials included: 6g of peach kernel, 6g of cordyceps sinensis, 6g of cape jasmine, 6g of Chinese angelica, 6g of crab shell, 6g of calcined gypsum, 6g of rhizoma anemarrhenae, 6g of medicated leaven, 6g of malt, 6g of mirabilite, 6g of rheum officinale, 6g of upper shell, 6g of lower shell, 6g of safflower, 6g of trichosanthes root, 6g of propolis, 6g of astragalus membranaceus, 6g of salvia miltiorrhiza and 6g of liquorice. The rest is the same as in example 1.

Example 11

An oral medicament comprising the following raw materials: 4g of peach kernel, 4g of cordyceps sinensis, 4g of cape jasmine fruit, 4g of Chinese angelica, 4g of crab shell, 4g of calcined gypsum, 4g of rhizoma anemarrhenae, 4g of medicated leaven, 4g of malt, 4g of mirabilite, 4g of rheum officinale, 4g of upper shell, 4g of lower shell, 4g of safflower, 4g of trichosanthes root, 4g of propolis, 4g of astragalus mongholicus, 4g of salvia miltiorrhiza and 4g of liquorice.

1) weighing the above peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rhubarb, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus, salvia miltiorrhiza and liquorice, cleaning the peach kernel, the cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rhubarb, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus, salvia miltiorrhiza and liquorice, then uniformly mixing, and extracting effective components after crushing to obtain the traditional Chinese medicine composition;

2) the traditional Chinese medicine composition is added with conventional auxiliary materials to prepare pills as oral medicaments.

Example 12

Compared to example 11, the oral medicament is a decoction. The rest is the same as in example 11.

Example 13

In contrast to example 1, oral solutions were prepared, the specification of which was 0.2/ml per bottle. The rest is the same as in example 1.

Example 14

The capsule size was 0.5g per capsule compared to example 1. The rest is the same as in example 1.

To verify the effect, the capsule (pyloric restoration capsule) prepared in example 1 of the present invention was orally administered to a patient suffering from helicobacter pylori. Through clinical application, common patients take effect in 5-7 days, take effect in 10-20 days slowly, obviously improve symptoms and cure the helicobacter pylori. The disease is not easy to relapse after being cured, and the relapse of the relapsed patient is avoided after the relapse of the drug is taken again.

According to the three-year cure and observation, 118 cases are cured, 15 cases are repeated, and the disease is not relapsed until 2 weeks after the medicine is taken again. The main symptoms are as follows: acid regurgitation, heartburn, flatulence, stomachache, halitosis, etc.

Case one:

wang in a certain place, man, 82 years old, Shandong Lanling county. The helicobacter pylori suffers from the helicobacter pylori for years, and the treatment cost of the helicobacter pylori and other caused diseases is as high as ten-million yuan per year. After the medicine is taken three years ago, the disease is cured for one week, the disease recurs after one year, and the disease does not recur after the medicine is taken again for one week.

Case two:

somebody yellow, woman, 43 years old, mountain dong lan ling county. Before three years, the body was unconsciously found to have helicobacter pylori treated by various methods for more than one year, and the triple therapy and the quadruple therapy of western medicine are also included. The medicine is taken two years before, and the patient is healed after one week. In order to consolidate the disease condition, the medicine is taken for a week, and the disease does not recur until now.

Case three:

some Lu, man, 11 years old, Shandong Lanling county. The patient suffering from helicobacter pylori takes the medicine before one year, and the patient is cured after five days, and the helicobacter pylori does not relapse.

It is characterized by that firstly, according to the Chinese medicine theory and following the principle of combining toxin, collaterals and bacteria toxin to cure, the invention can fully produce the goal of sterilizing, removing toxic material, dredging collaterals and radically curing pylorus, and develops said Chinese medicine composition with strong spectrum bactericidal action and repairing function of ulcer necrosis factor inflammatory mediator, and can be made into the Chinese medicine preparation. Clinical research proves that the formula not only has good therapeutic effect on helicobacter pylori, but also can effectively prevent other bacilli, ulcer and complications from forming, and remarkably improves the cure rate. Secondly, pharmacodynamic experiments are carried out, mainly in vivo antibacterial experiments of mice, and the results show that the death rate of the mice with high and medium doses is 15 percent, the content of platelets and fibrin is increased after the mice are taken, and the content of plasma is reduced. In addition, experiments on rabbits and sheep pigs show that the bacillus subtilis has good treatment effect on partial bacilli. Thirdly, the oral liquid prepared according to the traditional Chinese medicine composition has the same curative effect, 2-4 ml of the oral liquid is taken every day, and 1-2 ml of the oral liquid is taken every day by children, which are taken after meals. No side effect appears from the prior people taking the medicine. The dosage of the oral liquid is increased by about 30 to 200 grams for rabbits and dogs, the blood pressure is increased first and then is reduced, the blood pressure is recovered quickly, and the rabbits and dogs are slightly excited to breathe. The injection of 100 g/kg of oral liquid into mice can kill the mice; the death can also be caused by infusing 100 g/kg of the oral liquid into the abdominal cavity, specifically, the death is caused after the respiration is accelerated and then the coma occurs and 5 to 8 hours later.

While the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications of the invention may be made without departing from the scope of the invention.

Claims

1. A traditional Chinese medicine composition is characterized by comprising the following raw materials: peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rheum officinale, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus mongholicus, salvia miltiorrhiza and liquorice.

2. The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 1-20 parts of peach kernel, 1-20 parts of cordyceps sinensis, 1-20 parts of cape jasmine, 1-20 parts of angelica sinensis, 1-20 parts of crab shell, 1-20 parts of calcined gypsum, 1-20 parts of rhizoma anemarrhenae, 1-20 parts of medicated leaven, 1-20 parts of malt, 1-20 parts of mirabilite, 1-20 parts of rheum officinale, 1-20 parts of upper shell, 1-20 parts of lower shell, 1-20 parts of safflower, 1-20 parts of trichosanthes root, 1-20 parts of propolis, 1-20 parts of astragalus membranaceus, 1-20 parts of salvia miltiorrhiza and 1-20 parts of liquorice.

3. The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 2-10 parts of peach kernel, 2-10 parts of cordyceps sinensis, 2-10 parts of cape jasmine, 2-10 parts of angelica sinensis, 2-10 parts of crab shell, 2-10 parts of calcined gypsum, 2-10 parts of rhizoma anemarrhenae, 2-10 parts of medicated leaven, 2-10 parts of malt, 2-10 parts of mirabilite, 2-10 parts of rheum officinale, 2-10 parts of upper shell, 2-10 parts of lower shell, 2-10 parts of safflower, 2-10 parts of trichosanthes root, 2-10 parts of propolis, 2-10 parts of astragalus membranaceus, 2-10 parts of salvia miltiorrhiza and 2-10 parts of liquorice.

4. The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 4-6 parts of peach kernel, 4-6 parts of cordyceps sinensis, 4-6 parts of cape jasmine, 4-6 parts of angelica sinensis, 4-6 parts of crab shell, 4-6 parts of calcined gypsum, 4-6 parts of rhizoma anemarrhenae, 4-6 parts of medicated leaven, 4-6 parts of malt, 4-6 parts of mirabilite, 4-6 parts of rheum officinale, 4-6 parts of upper shell, 4-6 parts of lower shell, 4-6 parts of safflower, 4-6 parts of trichosanthes root, 4-6 parts of propolis, 4-6 parts of astragalus membranaceus, 4-6 parts of salvia miltiorrhiza and 4-6 parts of liquorice.

5. The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 5 parts of peach kernel, 5 parts of cordyceps sinensis, 5 parts of cape jasmine, 5 parts of angelica sinensis, 5 parts of crab shell, 5 parts of calcined gypsum, 5 parts of rhizoma anemarrhenae, 5 parts of medicated leaven, 5 parts of malt, 5 parts of mirabilite, 5 parts of rheum officinale, 5 parts of upper shell, 5 parts of lower shell, 5 parts of safflower, 5 parts of trichosanthes root, 5 parts of propolis, 5 parts of astragalus membranaceus, 5 parts of salvia miltiorrhiza and 5 parts of liquorice.

6. A method for preparing the Chinese medicinal composition as claimed in any one of claims 1 to 5, comprising the steps of: weighing peach kernel, cordyceps sinensis, gardenia, angelica sinensis, crab shell, calcined gypsum, rhizoma anemarrhenae, medicated leaven, malt, mirabilite, rheum officinale, upper shell, lower shell, safflower, trichosanthes root, propolis, astragalus mongholicus, salvia miltiorrhiza and liquorice according to the parts by weight, uniformly mixing, and crushing to obtain the traditional Chinese medicine composition.

7. The method of claim 6, further comprising the step of washing the peach kernel, the cordyceps sinensis, the gardenia, the angelica sinensis, the crab shell, the calcined gypsum, the rhizoma anemarrhenae, the medicated leaven, the malt, the mirabilite, the rhubarb, the upper shell, the lower shell, the safflower, the trichosanthes root, the propolis, the astragalus, the salvia miltiorrhiza and the liquorice before mixing.

8. An oral medicament comprising, in part or in whole, the Chinese medicinal composition of any one of claims 1 to 5.

9. The oral medicament of claim 8, wherein the dosage form of the oral medicament is a capsule, a pill or a decoction.

10. Use of an oral pharmaceutical according to claim 8 or 9 in the manufacture of a medicament for the treatment of helicobacter pylori disease.