CN112444634A - Sample analysis device and alarm method thereof - Google Patents

Sample analysis device and alarm method thereof Download PDF

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Publication number
CN112444634A
CN112444634A CN201910813744.8A CN201910813744A CN112444634A CN 112444634 A CN112444634 A CN 112444634A CN 201910813744 A CN201910813744 A CN 201910813744A CN 112444634 A CN112444634 A CN 112444634A
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alarm condition
alarm
editing area
area
module
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王志红
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers

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Abstract

A sample analysis device and an alarm method thereof display an alarm condition editing area for a user to edit an alarm condition in the alarm condition editing area through an input module; storing the edited alarm condition in the alarm condition editing area; and the alarm condition is called in the test process to judge whether the item test data triggers the alarm condition, so that the function of flexibly customizing the alarm scheme by a user is realized.

Description

Sample analysis device and alarm method thereof
Technical Field
The invention relates to a sample analysis device and an alarm method thereof.
Background
A sample analyzer is an apparatus for measuring and analyzing a sample, and typically includes a cell analyzer, a biochemical analyzer, an immunoassay analyzer, and the like. The products and the devices are generally designed with data alarm functions, and the functions are to judge whether the test process is abnormal or not based on reaction data of samples and reagents by using a calculation formula built in the system. The meaning of parameters related to a built-in calculation formula of products of various manufacturers is fixed in the products, a user can only use a data alarm function under a fixed formula framework, and at most, the size of some threshold values can be set, so that the flexibility is insufficient, and a plurality of problems can be caused.
For example, different test items, abnormal reaction processes aiming at different modes, such as substrate exhaustion of enzyme reaction, antigen surplus of antigen-antibody reaction, curve abnormality caused by sample interference, or curve form abnormality caused by the detection system itself, such as light source lamp fluctuation, reaction liquid bubbles or cross contamination, etc., alarm algorithm formulas and parameters required for the abnormal conditions are different, and the unified fixed formula is usually only suitable for a part of items; and as new projects are continuously developed and emerge, new data alarm requirements may emerge.
In order to meet different alarm requirements of different projects, a system needs to be designed and developed with a plurality of data alarm functions. This can have at least three consequences:
firstly, the system software development efficiency is low, and in order to meet the data alarm requirements of different projects, codes corresponding to multiple data alarm schemes need to be provided in the software respectively;
secondly, the long-term compatibility of the system is not facilitated, because each manufacturer in the industry usually continuously pushes out new reagent items, each item may have own characteristics and alarm requirements, and the solidified data alarm scheme is difficult to ensure backward compatibility with the data alarm requirements of future reagent items;
thirdly, the use of a data alarm function is not facilitated when a user uses a third-party reagent, because the solidified data alarm scheme designed and provided by an instrument manufacturer can not fully meet the data alarm requirements of other reagent manufacturers, the reliable and effective application of the third-party reagent on the instrument is restricted, the same manufacturer provides the instrument, a matched reagent, a matched calibrator and a matched detection program, and the instrument, the matched reagent, the matched calibrator and the matched detection program are comprehensively called as a detection system, and when the user does not use the matched reagent of the same instrument manufacturer but uses the reagents of other manufacturers, the reagents of other manufacturers are called as the third-party reagent; after the third-party reagent is used, the matching calibrator and the matching detection program provided by the original detection system are not directly applicable any more, and a user needs to establish a non-matching detection system again according to the selected reagent, wherein the establishment of data alarm parameters is included, and a completely established detection system is not available, so that reliable and effective performance guarantee is difficult to obtain.
Disclosure of Invention
In order to solve the above problems, the present application provides a sample analyzer and an alarm method thereof.
According to a first aspect, there is provided in an embodiment a sample analysis device comprising:
a sample part for carrying a sample;
the sample dispensing mechanism is used for sucking a sample and discharging the sample into a reaction cup to be added with the sample;
a reagent component for carrying a reagent;
the reagent dispensing mechanism is used for sucking the reagent and discharging the reagent into a reaction cup to be added with the reagent;
the blending mechanism is used for blending the reaction liquid to be blended in the reaction cup;
the reaction component is provided with at least one placing position, and the placing position is used for placing the reaction cup and incubating the reaction liquid in the reaction cup;
the light measurement component is used for performing light measurement on the incubated reaction liquid to obtain reaction data of the sample;
a memory for storing reaction data and alarm conditions of the sample;
the device comprises a display module, an input module and a processor; wherein:
the display module can display an alarm setting area comprising editing keys and alarm conditions; in response to clicking the editing key, the display module displays an alarm condition editing area, the alarm condition editing area is used for a user to edit and save an alarm condition in the alarm condition editing area through the input module, and the saved alarm condition is stored in the memory and displayed in the alarm setting area;
and the processor is used for acquiring the reaction data of the sample and judging whether the reaction process of the sample is normal or not according to the alarm condition.
According to a second aspect, there is provided in an embodiment a sample analysis device comprising:
the system comprises at least one functional module, a data processing module and a data processing module, wherein each functional module is used for completing at least one function required in the sample analysis process;
the input module is used for receiving input of a user;
the display module is used for displaying an alarm condition editing area so that a user can edit an alarm condition in the alarm condition editing area through the input module;
a memory for storing the edited alarm condition in the alarm condition editing area;
the processor is used for acquiring project test data when the functional module completes sample analysis and judging whether to trigger an alarm condition according to the project test data and the alarm condition in the memory;
and the alarm module is used for giving an alarm when the processor judges that the alarm condition is triggered.
In one embodiment, the alarm condition includes one or more judgment rules, and the judgment rules include a calculation formula, meanings of parameters in the calculation formula, and a judgment interval;
and the alarm condition editing area displayed by the display module is used for a user to edit at least a calculation formula of an alarm condition in the alarm condition editing area through the input module.
In one embodiment, the alarm condition editing area displayed by the display module is further used for a user to edit meanings of parameters in the calculation formula of the alarm condition in the alarm condition editing area through the input module.
In one embodiment, when the alarm condition includes a plurality of judgment rules, the alarm condition further includes a logical relationship between the plurality of judgment rules;
the alarm condition editing area displayed by the display module is also used for a user to edit at least the logic relation among the plurality of judgment rules of the alarm condition in the alarm condition editing area through the input module.
In one embodiment, the alarm condition editing area displayed by the display module comprises a calculation symbol area, a formula editing area and a parameter definition area; wherein:
the formula editing area is used for editing a calculation formula;
the calculation symbol region includes a plurality of calculation symbols; the calculation symbol area responds to the click of any one calculation symbol, and the clicked calculation symbol is input to the position of the current cursor in the formula editing area;
the parameter definition area is used for editing the meaning of the parameter in the calculation formula in the formula editing area.
In one embodiment, the alarm condition edit area displayed by the display module further includes a logical relationship area; wherein the logical relationship region comprises one or more logical symbols; and the logical relation area responds to clicking any one of the logical symbols and inputs the clicked logical symbol to the position of the current cursor in the formula editing area.
In one embodiment, the alarm condition editing area displayed by the display module is further configured to allow a user to edit at least an alarm identifier corresponding to an alarm condition in the alarm condition editing area through the input module;
and when the processor judges that the alarm condition is triggered, the alarm module drives the display module to display the alarm identifier corresponding to the alarm condition so as to alarm.
In one embodiment, the sample analysis device further comprises an interface coupled to the memory; the interface is used for connecting an external storage device so as to write the alarm condition in the memory into the external storage device.
According to a third aspect, there is provided in one embodiment a sample analysis device comprising:
the system comprises at least one functional module, a data processing module and a data processing module, wherein each functional module is used for completing at least one function required in the sample analysis process;
the interaction module is used for receiving data which is edited by a user and is related to the alarm condition;
a memory for storing the alarm condition;
the processor is used for acquiring project test data when the functional module completes sample analysis and judging whether to trigger an alarm condition according to the project test data and the alarm condition in the memory;
and the alarm module is used for giving an alarm when the processor judges that the alarm condition is triggered.
In one embodiment, the interaction module includes an interface module for receiving data about the alarm condition edited by the user to write the alarm condition to the memory for recall by the processor.
In one embodiment, the alarm condition includes one or more judgment rules, and the judgment rules include a calculation formula, meanings of parameters in the calculation formula, and a judgment interval; when the alarm condition comprises a plurality of judgment rules, the alarm condition also comprises a logical relationship among the judgment rules.
According to a fourth aspect, there is provided in one embodiment a method of alarming a sample analysis device, comprising:
displaying an alarm condition editing area;
editing an alarm condition in the alarm condition editing area in response to a user input to the alarm condition editing area;
storing the edited alarm condition in the alarm condition editing area for calling.
In one embodiment, the alarm condition includes one or more judgment rules, and the judgment rules include a calculation formula, meanings of parameters in the calculation formula, and a judgment interval;
the editing an alarm condition in the alarm condition editing area in response to the input of the user to the alarm condition editing area comprises: and in response to the input of the user to the alarm condition editing area, editing at least a calculation formula of an alarm condition and the meaning of parameters in the calculation formula in the alarm condition editing area.
In one embodiment, when the alarm condition includes a plurality of judgment rules, the alarm condition further includes a logical relationship between the plurality of judgment rules;
the editing an alarm condition in the alarm condition editing area in response to a user input to the alarm condition editing area, further comprising: and responding to the input of a user to the alarm condition editing area, and editing at least the logic relation among the plurality of judgment rules of the alarm condition in the alarm condition editing area.
In one embodiment, the editing an alarm condition in the alarm condition editing area in response to a user input to the alarm condition editing area further comprises: responding to the input of a user to the alarm condition editing area, and at least editing an alarm identifier corresponding to an alarm condition in the alarm condition editing area; the alarm identifier is used for being displayed when the corresponding alarm condition is triggered.
According to a fifth aspect, an embodiment provides a computer readable storage medium comprising a program executable by a processor to implement the method of any of the embodiments herein.
According to the sample analysis device, the alarm method and the computer-readable storage medium of the embodiment, the function of flexibly customizing the alarm scheme by the user is realized by receiving the data about the alarm condition edited by the user.
Drawings
FIGS. 1(a), 1(b) and 1(c) are schematic structural views of sample analyzers according to three embodiments;
FIG. 2 is a schematic structural view of a sample analyzer according to another embodiment;
FIG. 3 is a schematic diagram of an alarm setup area of an embodiment;
FIG. 4 is a schematic diagram of an alarm condition edit area of an embodiment;
FIG. 5 is a schematic structural view of a sample analyzer according to still another embodiment;
fig. 6 is a flowchart of an alarm method of a sample analysis apparatus according to an embodiment.
Detailed Description
The present invention will be described in further detail with reference to the following detailed description and accompanying drawings. Wherein like elements in different embodiments are numbered with like associated elements. In the following description, numerous details are set forth in order to provide a better understanding of the present application. However, those skilled in the art will readily recognize that some of the features may be omitted or replaced with other elements, materials, methods in different instances. In some instances, certain operations related to the present application have not been shown or described in detail in order to avoid obscuring the core of the present application from excessive description, and it is not necessary for those skilled in the art to describe these operations in detail, so that they may be fully understood from the description in the specification and the general knowledge in the art.
Furthermore, the features, operations, or characteristics described in the specification may be combined in any suitable manner to form various embodiments. Also, the various steps or actions in the method descriptions may be transposed or transposed in order, as will be apparent to one of ordinary skill in the art. Thus, the various sequences in the specification and drawings are for the purpose of describing certain embodiments only and are not intended to imply a required sequence unless otherwise indicated where such sequence must be followed.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings).
The invention provides a flexible data alarm solution, which can be used for a user to flexibly customize a data alarm function, for example, the user can edit (add or modify) an alarm condition, including but not limited to editing a calculation formula in the alarm condition, meaning of parameters in the calculation formula, a judgment condition, a threshold value and the like. In typical examples, the invention can provide an interactive software interface for a user to edit the alarm condition, and after the user edits the alarm condition, the device starts the corresponding alarm condition to judge the sample analysis process or result. Before the present invention is explained in detail, a structure of a sample analyzer will be explained.
Referring to fig. 1(a), some embodiments disclose a sample analysis apparatus, which includes at least one functional module 10 (or one or more functional modules 10), an interaction module 20, a memory 40, a processor 50, and an alarm module 60; referring to fig. 1(b), in some embodiments, the interaction module 20 of the sample analyzer may be mainly composed of an input module 21 and a display module 30; referring to fig. 1(c), in some embodiments, the interaction module 20 may also be mainly composed of an interface module 22; of course, it is understood that in some embodiments, the interaction module 20 may also include the input module 21, the display module 30, and the interface module 22 at the same time. The following are described separately.
Each functional module 10 is used for performing at least one function required in the sample analysis process, and the functional modules 10 cooperate together to perform the sample analysis to obtain the result of the sample analysis. Referring to fig. 2, a sample analyzer according to an embodiment is shown, in which some examples are given to the functional module 10. For example, the functional module 10 may include a sample cell 11, a sample dispensing mechanism 12, a reagent cell 13, a reagent dispensing mechanism 14, a kneading mechanism 15, a reaction cell 16, an optical measurement cell 17, and the like.
The sample block 11 is used to carry a sample. In some examples, the Sample unit 11 may include a Sample Delivery Module (SDM) and a front end rail; in other examples, the sample section 10 may be a sample disk including a plurality of sample sites on which sample tubes, for example, can be placed, and the sample disk may be configured to rotate to dispatch the sample to a corresponding position, for example, a position where the sample is aspirated by the sample pipetting mechanism 12.
The sample dispensing mechanism 12 is used for sucking a sample and discharging the sample into a reaction cup to be loaded. For example, the sample dispensing mechanism 12 may include a sample needle that performs a two-dimensional or three-dimensional motion in space by a two-dimensional or three-dimensional driving mechanism, so that the sample needle can move to aspirate a sample carried by the sample member 11 and to a cuvette to be loaded and discharge the sample to the cuvette.
The reagent component 13 is used to carry reagents. In one embodiment, the reagent unit 13 may be a reagent disk, which is configured in a disk-shaped structure and has a plurality of positions for holding reagent containers, and the reagent unit 13 can rotate and drive the reagent containers held by the reagent unit to rotate to a specific position, for example, a position for sucking reagent by the reagent dispensing mechanism 14. The number of the reagent member 13 may be one or more.
The reagent dispensing mechanism 14 is used to suck a reagent and discharge it into a reaction cuvette to which the reagent is to be added. In one embodiment, the reagent dispensing mechanism 14 may include a reagent needle that performs a two-dimensional or three-dimensional motion in space by a two-dimensional or three-dimensional driving mechanism, so that the reagent needle can move to aspirate a reagent carried by the reagent unit 13 and to a cuvette to which the reagent is to be added and discharge the reagent to the cuvette.
The mixing mechanism 15 is used for mixing the reaction liquid to be mixed in the reaction cup. The number of the kneading mechanisms 15 may be one or more.
The reaction unit 16 has at least one placement site for placing a cuvette and incubating a reaction solution in the cuvette. For example, the reaction component 16 may be a reaction tray, which is configured in a disc-shaped structure and has one or more placing positions for placing reaction cups, and the reaction tray can rotate and drive the reaction cups in the placing positions to rotate for scheduling the reaction cups in the reaction tray and incubating reaction liquid in the reaction cups.
The photometric unit 17 is used to perform photometric measurement on the reaction solution after completion of incubation, and to obtain reaction data of the sample. For example, the photodetector 17 detects the light emission intensity of the reaction solution to be measured, and calculates the concentration of the component to be measured in the sample from the calibration curve. In one embodiment, the photometric component 17 is separately disposed outside the reaction component 16.
While the functional module 10 has been described above by way of example, the following description will proceed with respect to other components and structures of the sample analyzer.
The interactive module 20 is adapted to receive user-edited data regarding alarm conditions, and the memory 40 is adapted to store the alarm conditions. This can be achieved by the input module 21 and the display module 30, or by the interface module 22, as will be described separately below.
The input module 21 is used for receiving input of a user. The input module 21 may be a mouse, a keyboard, or the like, as is common, and in some cases, may be a touch display screen, which provides a function for a user to input and display contents, so that the input module 21 and the display module 30 are integrated in this example. Of course, in some examples, the input module 21 may even be a voice input device or the like that brings about recognition of speech.
The display module 30 may be used to display information. In some embodiments, the sample analysis apparatus may be integrated with the display module, and in some embodiments, the sample analysis apparatus may also be connected to a computer device (e.g., a computer) to display information through a display unit (e.g., a display screen) of the computer device, which are all within the scope of the present disclosure defined and protected by the display module 30.
Referring to fig. 3, in an embodiment, the display module 30 can display an alarm setting area of the alarm condition. The alarm device area may display the alarm condition, e.g. display the name of the alarm condition, or even display the specific content of the alarm condition, such as a calculation formula or the like. Fig. 3 is an example of displaying the names of alarm conditions. In some embodiments, the alarm setup area may also contain an edit button. In response to clicking of the edit key, for example, a user clicking the edit key with a mouse or the like, the display module 30 displays an alarm condition edit area for the user to edit the alarm condition. The edit key may be an add key or a modify key, and in some examples, the alarm setting area may further include a delete key. In the specific implementation process, a user can select a certain alarm condition in the alarm setting area, and when a modification key is clicked again, an alarm condition editing area is generated and used for re-editing and modifying the selected alarm condition; if the user selects a certain alarm condition in the alarm setting area and clicks the delete key, the selected alarm condition is deleted. The example shown in figure 3 is a schematic representation of the alarm condition being selected for substrate exhaustion. And if the user clicks an increase key in the alarm setting area, an alarm condition editing area is generated for the user to add and edit new alarm conditions. It is to be understood that the above is one way of generating the alarm condition edit area, i.e. by clicking on the edit button, and in other embodiments, it will be apparent to those skilled in the art that the generation of the alarm condition edit area may be triggered in other ways. Some description of the alarm condition edit area follows.
The alarm condition editing area displayed by the display module 30 is used for the user to edit the alarm condition in the alarm condition editing area through the input module 21. In some embodiments, the alarm condition may include one or more judgment rules, and each judgment rule may include a calculation formula, a meaning of a parameter in the calculation formula, a judgment interval, and the like. In some embodiments, when the alarm condition includes a plurality of judgment rules, the plurality of judgment rules have a logical relationship therebetween, such as a logical relationship of "and" or ". For example, when an alarm condition a includes a judgment rule 1 and a judgment rule 2, if the logical relationship between the two judgment rules is "and", it means that the alarm condition a is triggered to alarm only when both the judgment rule 1 and the judgment rule 2 are triggered; if the logical relationship between the two judgment rules is "or", it means that the alarm condition a is triggered to alarm as long as any one of the judgment rule 1 and the judgment rule 2 is triggered.
The user can edit one or more of a calculation formula of the judgment rule, meanings of parameters in the calculation formula, a logical relationship between the judgment section and the judgment rule, and the like in the alarm condition editing region through the input module 21. In order to facilitate the user to edit the alarm condition, the alarm condition editing area in an embodiment includes one or more of a calculation symbol area, a formula editing area, a parameter definition area, and a logical relationship area. FIG. 4 is an example of an alarm condition edit area including a calculation symbol area, a formula edit area, a parameter definition area, and a logical relationship area. The following describes a calculation symbol area, a formula editing area, a parameter definition area, a logical relationship area, and the like in the alarm condition editing area.
The formula editing area is used for editing the calculation formula. The user can edit the calculation formula in the formula editing area. The calculation symbol area includes a plurality of calculation symbols. And the calculation symbol area responds to clicking any one calculation symbol, and the clicked calculation symbol is input to the position of the current cursor in the formula editing area. The parameter definition area is used for editing the meaning of the parameter in the calculation formula in the formula editing area. The logical relationship area comprises one or more logical symbols; and the logical relation area responds to clicking any one of the logical symbols and inputs the clicked logical symbol to the position of the current cursor in the formula editing area.
For example, for a biochemical project B, the user needs to add a new alarm condition for substrate exhaustion judgment to the project B, and the alarm condition includes judgment rule B1 and judgment rule B2.
The judgment rule B1 is determined by the following calculation formula:
Figure BDA0002185765510000091
wherein, a and B represent two end points of the region, the last parameter in the parentheses may be Y, or may be N, that is, Y/N is a selection item, and they jointly form the judgment region of the judgment rule B1, for example, when it is Y, it represents that when the result calculated by the above formula is in [ a, B ], the judgment rule B1 is triggered; when N, it means that the result of the above formula calculation does not fall within [ a, B ], the judgment rule B1 is triggered. q1, q2, q3 and q4 are the 4 photometric point sequences of the reaction process data of item B, and n1 is the wavelength parameter corresponding to the reaction process data of item B; aq1 is the absorbance at the photometric point with the number q1 at wavelength n1, Aq2 is the absorbance at the photometric point with the number q2 at wavelength n1, Aq3 is the absorbance at the photometric point with the number q3 at wavelength n1, and Aq4 is the absorbance at the photometric point with the number q4 at wavelength n 1. The absorbances Aq1, Aq2, Aq3, and Aq4 at the photometric point of q1, q2, q3, and q4 at the wavelength n1 can be acquired by the photometric unit 17 of the sample analysis device.
When the user needs to add the judgment rule B1 to the alarm condition editing area, the calculation formula of the judgment rule B1 is input in the formula editing area through a keyboard or the like, and a calculation symbol in the calculation formula, such as a minus sign or the like, can be input through the keyboard or can be input by clicking a calculation symbol in the calculation symbol area, such as a minus sign or the like; the meanings of the parameters in the calculation formula can be defined in a parameter definition area, for example, the parameter definition area obtains and displays the parameters in the calculation formula in a formula editing area, the parameter definition area also has a selection box of a pulling part, the meanings of the parameters possibly used in the selection box are possible, a user selects one parameter displayed in the parameter definition area firstly, then the pulling part in the selection box is pulled up and down to check the meaning displayed in the selection box, one meaning in the selection box is selected through clicking to define the selected parameter, and the meanings of the parameters can be defined through the operations in sequence.
The judgment rule B2 is determined by the following calculation formula:
Figure BDA0002185765510000092
wherein c represents a threshold, the last parameter in the parentheses may be Y, or may be N, that is, Y/N is a selection item, and they jointly form a judgment region of the judgment rule B2, for example, when Y is Y, it represents that when the result calculated by the above formula is greater than c, the judgment rule B2 is triggered; if the value is N, the result of the formula calculation is smaller than c, and a judgment rule B2 is triggered; l is the starting point of the calculation time, M' is the end point of the calculation time, AiIs the absorbance at the point i, and,
Figure BDA0002185765510000093
is the average absorbance at the point L to M', TiIs the actual photometric time (in seconds) of the i point,
Figure BDA0002185765510000094
the average time from L to M points. Understandably, suction of any one point iThe luminosity can be acquired by the photometric component 17 of the sample analysis device. The absorbance in the formula does not define a wavelength, and the processor 50 considers the wavelength to be the dominant wavelength by default; of course, the calculation formula in the judgment rule B2 may be added and defined as a parameter in the parentheses thereof to represent the wavelength as in the judgment rule B1. Similar to the editing of the calculation formula of the determination rule B1 and the meanings of the parameters, the user can edit the calculation formula of the determination rule B2 and the meanings of the parameters in the alarm condition editing area, which will not be described herein again.
Since the alarm condition of the newly added substrate exhaustion judgment of the item B comprises two judgment rules, the user needs to edit the logical relationship between the two judgment rules B1 and B2, and the user can input "OR" between the calculation formulas of the judgment rules B1 and B2 in the alarm condition editing area through a keyboard to indicate that the logical relationship between the two judgment rules is "OR", OR can complete the input by clicking the logical symbol "OR" in the logical relationship area.
For enabling a user to quickly identify and locate a problem when a project test is abnormal, in some embodiments, the alarm condition editing area displayed by the display module 30 is further used for the user to edit an alarm identifier corresponding to an alarm condition in the alarm condition editing area through the input module 21, so that when an alarm condition is triggered, the display module 30 can display a corresponding alarm identifier for the user to identify and locate the problem.
In some examples, the alarm condition editing area may have a save button, and after the user clicks the save button, the alarm condition edited by the alarm condition editing area is saved, and the alarm condition editing area disappears; in other examples, the alarm condition edit area may not have a save button, and the alarm condition edited by the alarm condition edit area is automatically saved when the user closes the alarm condition edit area. The memory 40 is used to store alarm conditions, for example, alarm conditions edited in an alarm condition editing area. In some embodiments, the memory 40 also stores project test data for the sample, the project test data including project reaction process data and/or result data. It is noted that the term "reaction data" as used herein may refer to project reaction process data and/or result data in some instances.
The above are some embodiments where the meaning of the parameters in the calculation formula is also editable. In other embodiments, the memory 40 is preset with meanings of each parameter, the user only needs to edit the calculation formula, and the processor 50 identifies and invokes the alarm condition edited by the user according to the meanings of each parameter preset and defined in the memory 40; in which case the alarm condition edit area may not include a parameter definition area. For example, one scenario is that the user only needs to write the calculation formula of the alarm condition in the alarm condition editing area, and does not need to define the meaning of each parameter in the calculation formula in the alarm condition editing area, because the meaning of each parameter in the calculation formula is previously defined, for example, for the above-mentioned judgment rule B1, each parameter in the calculation formula is previously defined, and the user directly uses these parameters to construct the calculation formula.
The above are some illustrations of user customization of alarm conditions, typically for use of the sample analysis apparatus and operator customization of alarm conditions in the alarm condition editing area displayed by the display module 30 via the input module 21, which allows the sample analysis apparatus to implement the function of user-flexibly customizing of alarm scenarios.
In some embodiments, the sample analysis device may also implement the functionality of a custom alarm scheme via the interface module 22. In particular, interface module 22 is configured to receive user-edited data regarding alarm conditions to write the alarm conditions to memory 40 for recall by processor 50.
In some embodiments, the user-edited data regarding the alarm condition may be a file in a predetermined format, such as txt format or other format, which is stored by the interface module 22 in a predetermined directory in the memory 40 of the sample analysis device for retrieval by the processor 50.
In some embodiments, the data about the alarm condition edited by the user may also be an executable script file, which is executed by the processor after being stored by the interface module 22, and the alarm condition therein is parsed and stored in the memory 40 for later recall.
The interface module 22 provides a secondary development interface for users, typically reagent manufacturers or product agents, through which the user can flexibly customize the functionality of the alarm scheme, such as establishing or completing data alarm functions for certain projects.
The processor 50 is configured to obtain the item test data when the functional module 10 completes the sample analysis, and determine whether to trigger an alarm condition according to the item test data and the alarm condition in the memory 40. In some embodiments, the processor 50 obtains the reaction data of the sample and determines whether the reaction process of the sample is normal according to the alarm condition; for example, the processor 50 determines whether substrate depletion has occurred in the sample during the test item B based on the alarm condition for substrate depletion determination of item B described above.
The alarm module 60 is configured to alarm when the processor 50 determines that an alarm condition is triggered. In some embodiments, when the alarm condition has a corresponding alarm identifier, the alarm module 60 drives the display module 30 to display the alarm identifier corresponding to the alarm condition for alarming when the processor 50 determines that the alarm condition is triggered. In some examples, alarm module 60 may be hardware with a display function, and even alarm module 60 may be integrated with display module 30 to alert and prompt a user by displaying content.
Referring to fig. 5, the sample analyzer of some embodiments may further include an interface 70 connected to the memory 40, where the interface 70 may be capable of connecting an external storage device, such as a usb disk, and a user may plug the external storage device, such as a usb disk, into the sample analyzer through the interface 70 and copy the alarm condition stored in the memory 40, so as to facilitate the user to migrate to another device.
The above are some descriptions of the sample analysis device of the present invention.
The invention also discloses an alarm method of the sample analysis device in some embodiments. Referring to fig. 6, an exemplary alarm method includes steps 100 to 120, which are described in detail below.
Step 100: and displaying an alarm condition editing area.
The alarm condition editing area is used for a user to edit the alarm condition. In some embodiments, the alarm condition may include one or more judgment rules, and each judgment rule may include a calculation formula, a meaning of a parameter in the calculation formula, a judgment interval, and the like. In some embodiments, when the alarm condition includes a plurality of judgment rules, the plurality of judgment rules have a logical relationship therebetween, such as a logical relationship of "and" or ". For example, when an alarm condition a includes a judgment rule 1 and a judgment rule 2, if the logical relationship between the two judgment rules is "and", it means that the alarm condition a is triggered to alarm only when both the judgment rule 1 and the judgment rule 2 are triggered; if the logical relationship between the two judgment rules is "or", it means that the alarm condition a is triggered to alarm as long as any one of the judgment rule 1 and the judgment rule 2 is triggered. And editing one or more of a calculation formula of the judgment rule, the meaning of parameters in the calculation formula, a logical relation between the judgment interval and the judgment rule and the like in the alarm condition editing area by a user through a mouse or a keyboard.
In addition, for enabling a user to quickly identify and locate problems when a project test is abnormal, the alarm condition editing area in some embodiments is further used for editing an alarm identifier corresponding to an alarm condition, and the alarm identifier is used for being displayed when the corresponding alarm condition is triggered.
Step 110: and editing an alarm condition in the alarm condition editing area in response to the input of the user to the alarm condition editing area.
For example, in some examples, step 110 may include: and in response to the input of the user to the alarm condition editing area, editing at least a calculation formula of an alarm condition and the meaning of parameters in the calculation formula in the alarm condition editing area. In some examples, step 110 may include: and responding to the input of a user to the alarm condition editing area, and editing at least the logic relation among the plurality of judgment rules of the alarm condition in the alarm condition editing area. In some examples, step 110 may include: and responding to the input of the user to the alarm condition editing area, and editing at least an alarm identifier corresponding to the alarm condition in the alarm condition editing area.
In order to facilitate the user to edit the alarm condition, the alarm condition editing area in an embodiment includes one or more of a calculation symbol area, a formula editing area, a parameter definition area, and a logical relationship area. The formula editing area is used for editing the calculation formula. The user can edit the calculation formula in the formula editing area. The calculation symbol area includes a plurality of calculation symbols. And the calculation symbol area responds to clicking any one calculation symbol, and the clicked calculation symbol is input to the position of the current cursor in the formula editing area. The parameter definition area is used for editing the meaning of the parameter in the calculation formula in the formula editing area. The logical relationship area comprises one or more logical symbols; and the logical relation area responds to clicking any one of the logical symbols and inputs the clicked logical symbol to the position of the current cursor in the formula editing area.
Step 120: storing the edited alarm condition in the alarm condition editing area for calling. For example, in the test process, whether the alarm bar is triggered is judged by acquiring the project test data and according to the stored alarm conditions.
The above are some of the descriptions of the alarm method of the present invention.
Aiming at the limitations existing in the prior art, the invention provides a flexible data alarm solution. By implementing the invention, the user can flexibly customize and edit the alarm condition. For example, biochemical project testing, whose customizable content with respect to alarm conditions includes, but is not limited to: a data alarm calculation formula, wavelength information, photometric point information, an alarm threshold value and the like used by the calculation formula; each alarm condition may comprise one or more calculation formulas, each formula having its own judgment interval, or judgment condition and corresponding threshold; when multiple calculation formulas are combined, the logical relationship between the calculation formulas can be AND or OR; the alarm condition may be customized for each item, or may be a customized general alarm condition, and the alarm condition may be activated for an item that needs to use the alarm condition. The way of customizing the alarm condition can be to provide a corresponding editing interface on a software interface or provide an interface for secondary development of a user. The users include not only end users, but also intermediate users, such as some reagent manufacturers or product agents, which establish or perfect data alarm functions for some projects by using customized functions or secondary development interfaces provided by software; the system also comprises internal personnel of a manufacturer, so that the system function is conveniently expanded and enriched, and a personalized data alarm scheme is realized by directly utilizing a customized function or a secondary development interface provided by software without directly writing software codes.
Reference is made herein to various exemplary embodiments. However, those skilled in the art will recognize that changes and modifications may be made to the exemplary embodiments without departing from the scope hereof. For example, the various operational steps, as well as the components used to perform the operational steps, may be implemented in differing ways depending upon the particular application or consideration of any number of cost functions associated with operation of the system (e.g., one or more steps may be deleted, modified or incorporated into other steps).
In the above embodiments, the implementation may be wholly or partially realized by software, hardware, firmware, or any combination thereof. Additionally, as will be appreciated by one skilled in the art, the principles herein may be reflected in a computer program product on a computer readable storage medium, which is pre-loaded with computer readable program code. Any tangible, non-transitory computer-readable storage medium may be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-to-ROM, DVD, Blu-Ray discs, etc.), flash memory, and/or the like. These computer program instructions may be loaded onto a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions which execute on the computer or other programmable data processing apparatus create means for implementing the functions specified. These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including means for implementing the function specified. The computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified.
While the principles herein have been illustrated in various embodiments, many modifications of structure, arrangement, proportions, elements, materials, and components particularly adapted to specific environments and operative requirements may be employed without departing from the principles and scope of the present disclosure. The above modifications and other changes or modifications are intended to be included within the scope of this document.
The foregoing detailed description has been described with reference to various embodiments. However, one skilled in the art will recognize that various modifications and changes may be made without departing from the scope of the present disclosure. Accordingly, the disclosure is to be considered in an illustrative and not a restrictive sense, and all such modifications are intended to be included within the scope thereof. Also, advantages, other advantages, and solutions to problems have been described above with regard to various embodiments. However, the benefits, advantages, solutions to problems, and any element(s) that may cause any element(s) to occur or become more pronounced are not to be construed as a critical, required, or essential feature or element of any or all the claims. As used herein, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, system, article, or apparatus. Furthermore, the term "coupled," and any other variation thereof, as used herein, refers to a physical connection, an electrical connection, a magnetic connection, an optical connection, a communicative connection, a functional connection, and/or any other connection.
Those skilled in the art will recognize that many changes may be made to the details of the above-described embodiments without departing from the underlying principles of the invention.

Claims (17)

1. A sample analysis apparatus, comprising:
a sample part for carrying a sample;
the sample dispensing mechanism is used for sucking a sample and discharging the sample into a reaction cup to be added with the sample;
a reagent component for carrying a reagent;
the reagent dispensing mechanism is used for sucking the reagent and discharging the reagent into a reaction cup to be added with the reagent;
the blending mechanism is used for blending the reaction liquid to be blended in the reaction cup;
the reaction component is provided with at least one placing position, and the placing position is used for placing the reaction cup and incubating the reaction liquid in the reaction cup;
the light measurement component is used for performing light measurement on the incubated reaction liquid to obtain reaction data of the sample;
a memory for storing reaction data and alarm conditions of the sample;
the device comprises a display module, an input module and a processor; wherein:
the display module can display an alarm setting area comprising editing keys and alarm conditions; in response to clicking the editing key, the display module displays an alarm condition editing area, the alarm condition editing area is used for a user to edit and save an alarm condition in the alarm condition editing area through the input module, and the saved alarm condition is stored in the memory and displayed in the alarm setting area;
and the processor is used for acquiring the reaction data of the sample and judging whether the reaction process of the sample is normal or not according to the alarm condition.
2. A sample analysis apparatus, comprising:
the system comprises at least one functional module, a data processing module and a data processing module, wherein each functional module is used for completing at least one function required in the sample analysis process;
the input module is used for receiving input of a user;
the display module is used for displaying an alarm condition editing area so that a user can edit an alarm condition in the alarm condition editing area through the input module;
a memory for storing the edited alarm condition in the alarm condition editing area;
the processor is used for acquiring project test data when the functional module completes sample analysis and judging whether to trigger an alarm condition according to the project test data and the alarm condition in the memory;
and the alarm module is used for giving an alarm when the processor judges that the alarm condition is triggered.
3. The sample analysis apparatus according to claim 2, wherein the alarm condition includes one or more judgment rules including a calculation formula, a meaning of a parameter in the calculation formula, and a judgment section;
and the alarm condition editing area displayed by the display module is used for a user to edit at least a calculation formula of an alarm condition in the alarm condition editing area through the input module.
4. The sample analysis device of claim 3, wherein the alarm condition edit area displayed by the display module is further for a user to edit, via the input module, the meaning of a parameter in the calculation formula of an alarm condition in the alarm condition edit area.
5. The sample analyzing apparatus according to claim 3, wherein when the alarm condition includes a plurality of judgment rules, the alarm condition further includes a logical relationship between the plurality of judgment rules;
the alarm condition editing area displayed by the display module is also used for a user to edit at least the logic relation among the plurality of judgment rules of the alarm condition in the alarm condition editing area through the input module.
6. The sample analysis device of any of claims 3 to 5, wherein the alarm condition edit region displayed by the display module includes one or more of a calculation symbol region, a formula edit region, and a parameter definition region; wherein:
the formula editing area is used for editing a calculation formula;
the calculation symbol region includes a plurality of calculation symbols; the calculation symbol area responds to the click of any one calculation symbol, and the clicked calculation symbol is input to the position of the current cursor in the formula editing area;
the parameter definition area is used for editing the meaning of the parameter in the calculation formula in the formula editing area.
7. The sample analysis device of claim 6, wherein the alarm condition edit area displayed by the display module further comprises a logical relationship area; wherein the logical relationship region comprises one or more logical symbols; and the logical relation area responds to clicking any one of the logical symbols and inputs the clicked logical symbol to the position of the current cursor in the formula editing area.
8. The sample analysis device according to any one of claims 3 to 5, wherein the alarm condition editing area displayed by the display module is further configured for a user to edit at least an alarm identifier corresponding to an alarm condition in the alarm condition editing area through the input module;
and when the processor judges that the alarm condition is triggered, the alarm module drives the display module to display the alarm identifier corresponding to the alarm condition so as to alarm.
9. The sample analysis device of claim 2, further comprising an interface coupled to the memory; the interface is used for connecting an external storage device so as to write the alarm condition in the memory into the external storage device.
10. A sample analysis apparatus, comprising:
the system comprises at least one functional module, a data processing module and a data processing module, wherein each functional module is used for completing at least one function required in the sample analysis process;
the interaction module is used for receiving data which is edited by a user and is related to the alarm condition;
a memory for storing the alarm condition;
the processor is used for acquiring project test data when the functional module completes sample analysis and judging whether to trigger an alarm condition according to the project test data and the alarm condition in the memory;
and the alarm module is used for giving an alarm when the processor judges that the alarm condition is triggered.
11. The sample analysis device of claim 10, wherein the interaction module comprises an interface module to receive data about an alarm condition edited by the user to write the alarm condition to the memory for recall by a processor.
12. The sample analyzing apparatus according to claim 10, wherein the alarm condition includes one or more judgment rules including a calculation formula, a meaning of a parameter in the calculation formula, and a judgment section; when the alarm condition comprises a plurality of judgment rules, the alarm condition also comprises a logical relationship among the judgment rules.
13. An alarm method of a sample analyzer, comprising:
displaying an alarm condition editing area;
editing an alarm condition in the alarm condition editing area in response to a user input to the alarm condition editing area;
storing the edited alarm condition in the alarm condition editing area for calling.
14. An alarm method according to claim 13, wherein the alarm condition includes one or more judgment rules including a calculation formula, a meaning of a parameter in the calculation formula, and a judgment section;
the editing an alarm condition in the alarm condition editing area in response to the input of the user to the alarm condition editing area comprises: and in response to the input of the user to the alarm condition editing area, editing at least a calculation formula of an alarm condition and the meaning of parameters in the calculation formula in the alarm condition editing area.
15. An alarm method according to claim 14, wherein when said alarm condition includes a plurality of judgment rules, said alarm condition further includes a logical relationship between said plurality of judgment rules;
the editing an alarm condition in the alarm condition editing area in response to a user input to the alarm condition editing area, further comprising: and responding to the input of a user to the alarm condition editing area, and editing at least the logic relation among the plurality of judgment rules of the alarm condition in the alarm condition editing area.
16. The alarm method of claim 14 or 15, wherein said editing an alarm condition in said alarm condition editing area in response to a user input to said alarm condition editing area, further comprises: responding to the input of a user to the alarm condition editing area, and at least editing an alarm identifier corresponding to an alarm condition in the alarm condition editing area; the alarm identifier is used for being displayed when the corresponding alarm condition is triggered.
17. A computer-readable storage medium, characterized by comprising a program executable by a processor to implement the method of any one of claims 13 to 16.
CN201910813744.8A 2019-08-30 2019-08-30 Sample analysis device and alarm method thereof Pending CN112444634A (en)

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