CN112438924A - 一种中药漱口水 - Google Patents

一种中药漱口水 Download PDF

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CN112438924A
CN112438924A CN202011371306.XA CN202011371306A CN112438924A CN 112438924 A CN112438924 A CN 112438924A CN 202011371306 A CN202011371306 A CN 202011371306A CN 112438924 A CN112438924 A CN 112438924A
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extract
percent
traditional chinese
chinese medicine
mouthwash
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赵振宇
马春霞
刘�东
张文晋
李衍达
孙嘉惠
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Shandong Analysis and Test Center
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Abstract

本发明公开了一种中药漱口水，所述中药漱口水包括清热类中药:石膏提取物、紫花地丁提取物、金银花提取物、连翘提取物、紫荆皮提取物、黄芩提取物、板蓝根提取物；止痛类中药:白芷提取物、花椒提取物、丁香提取物、芒硝提取物、硼砂提取物；清新口气类中药:冰片提取物、薄荷提取物；辅料为三乙醇胺、二烷基硫酸钠、余量为纯净水。本发明清热类中药的功效为清热解毒、清肺胃火、抑制口腔特别是牙齿、牙龈细菌的繁殖等，止痛类中药则具有缓急止痛，减轻龋齿、牙周带来的不适感的功效，清新口气类中药则具有去除口腔异味，改善口气的作用。三者紧密配合，构成配方合理，针对多种口腔问题的漱口水。

Description

一种中药漱口水
技术领域
本发明涉及日用品领域，特别涉及一种中药漱口水。
背景技术
漱口水，是人们日常生活中常用的日用品，其对牙齿、牙龈的保护已逐渐被人们重视。
我国自古以来就有漱口水的使用，特别是清宫医案中关于太医使用漱口水治疗光绪皇帝牙周疾病的成功案例，更说明了在漱口水中添加一些中药成分，对于牙齿、牙龈有保护作用，甚至可以不通过手术治疗年久病深的牙周疾病。中医认为牙龈为阳明经循行所过，齿为骨之余。牙周疾病主要与阳明经的胃和大肠，已经肾的关系密切。其病因病机多为胃火、大肠湿热、虚火上炎等导致。用于日常牙周保健的中药，要以清热、止痛、清新口气等三类为主。
目前，市面上的漱口水很少添加中药成分，导致其仅有清洁作用，而无治疗作用。
发明内容
本发明为了弥补现有技术的不足，提供了一种中药漱口水。
本发明是通过如下技术方案实现的：一种中药漱口水，所述中药漱口水由以下重量配比的原料制成：清热类中药:石膏提取物0.03%-0.05%、紫花地丁提取物0.01%-0.05%、金银花提取物0.01%-0.05%、连翘提取物0.01%-0.05%、紫荆皮提取物0.01%-0.05%、黄芩提取物0.01%-0.05%、板蓝根提取物0.01%-0.05%；止痛类中药:白芷提取物0.01%-0.05%、花椒提取物0.01%-0.05%、丁香提取物0.01%-0.05%、芒硝提取物0.01%-0.05%、硼砂提取物0.01%-0.05%；清新口气类中药:冰片提取物0.01%-0.05%、薄荷提取物0.01%-0.05%；辅料为三乙醇胺、二烷基硫酸钠1.0％-3.0％、余量为纯净水。
优选的，所述石膏提取物、芒硝提取物、硼砂提取物为水提物。
优选的，所述紫花地丁提取物、金银花提取物、紫荆皮提取物、黄芩提取物、板蓝根提取物、花椒提取物为70%乙醇提物。
优选的，所述连翘提取物为水蒸气蒸馏法提取物与70%乙醇提取物混合提取物。
优选的，所述丁香提取物为水蒸气蒸馏法提取物。
与现有技术相比，本发明的有益之处为：
本发明包括清热类中药、止痛类中药和清新口气类中药，清热类中药的功效为清热解毒、清肺胃火、抑制口腔特别是牙齿、牙龈细菌的繁殖等，止痛类中药则具有缓急止痛，减轻龋齿、牙周带来的不适感的功效，清新口气类中药则具有去除口腔异味，改善口气的作用。三者紧密配合，构成配方合理，针对多种口腔问题的漱口水。
本发明增加了漱口水的清热功效、止痛功效、清新口气的功效等，使漱口水的适用人群更广，基本针对常见的口腔问题均产生不同程度的缓解作用。
附图说明
下面结合附图对本发明作进一步的说明。
图1为本发明患者使用中药漱口水前后口腔照片图。
具体实施方式
下面结合具体实施例对本发明做进一步的详细说明，以令本领域技术人员参照说明书文字能够据以实施。
本发明将清热类中药、止痛类中药和清新口气类中药分别命名为A、B、C三类药物，然后进行药物配置。
实施例1
一种中药漱口水，所述中药漱口水由以下重量配比的原料制成：
清热类中药A类:石膏提取物0.01%、紫花地丁提取物0.01%、金银花提取物0.01%、连翘提取物0.01%、紫荆皮提取物0.01%、黄芩提取物0.01%、板蓝根提取物0.01%；
止痛类中药B类:白芷提取物0.01%、花椒提取物0.01%、丁香提取物0.01%、芒硝提取物0.01%、硼砂提取物0.01%；
清新口气类中药C类:冰片提取物0.01%、薄荷提取物0.01%；
辅料为三乙醇胺、二烷基硫酸钠1.0％-3.0％、余量为纯净水。
本实施案例中，石膏提取物、芒硝提取物、硼砂提取物为水提物；紫花地丁提取物、金银花提取物、紫荆皮提取物、黄芩提取物、板蓝根提取物、花椒提取物为70%乙醇提物；连翘提取物为水蒸气蒸馏法提取物与70%乙醇提取物混合提取物，混合比例为1：1；丁香提取物为水蒸气蒸馏法提取物。
实施例2
一种中药漱口水，所述中药漱口水由以下重量配比的原料制成：
清热类中药A类:石膏提取物0.01%、紫花地丁提取物0.01%、金银花提取物0.01%、连翘提取物0.01%、紫荆皮提取物0.01%、黄芩提取物0.01%、板蓝根提取物0.01%；
止痛类中药B类:白芷提取物0.02%、花椒提取物0.02%、丁香提取物0.02%、芒硝提取物0.02%、硼砂提取物0.02%；
清新口气类中药C类:冰片提取物0.02%、薄荷提取物0.02%；
辅料为三乙醇胺、二烷基硫酸钠1.0％-3.0％、余量为纯净水。
本实施案例中，石膏提取物、芒硝提取物、硼砂提取物为水提物；紫花地丁提取物、金银花提取物、紫荆皮提取物、黄芩提取物、板蓝根提取物、花椒提取物为70%乙醇提物；连翘提取物为水蒸气蒸馏法提取物与70%乙醇提取物混合提取物，混合比例为1:1；丁香提取物为水蒸气蒸馏法提取物。
实施例3
一种中药漱口水，所述中药漱口水由以下重量配比的原料制成：
清热类中药A类:石膏提取物0.02%、紫花地丁提取物0.02%、金银花提取物0.02%、连翘提取物0.02%、紫荆皮提取物0.02%、黄芩提取物0.02%、板蓝根提取物0.02%；
止痛类中药B类:白芷提取物0.01%、花椒提取物0.01%、丁香提取物0.01%、芒硝提取物0.01%、硼砂提取物0.01%；
清新口气类中药C类:冰片提取物0.02%、薄荷提取物0.02%；
辅料为三乙醇胺、二烷基硫酸钠1.0％-3.0％、余量为纯净水。
本实施案例中，石膏提取物、芒硝提取物、硼砂提取物为水提物；紫花地丁提取物、金银花提取物、紫荆皮提取物、黄芩提取物、板蓝根提取物、花椒提取物为70%乙醇提物；连翘提取物为水蒸气蒸馏法提取物与70%乙醇提取物混合提取物，混合比例为1：1；丁香提取物为水蒸气蒸馏法提取物。
实施例4
一种中药漱口水，所述中药漱口水由以下重量配比的原料制成：
清热类中药A类:石膏提取物0.02%、紫花地丁提取物0.02%、金银花提取物0.02%、连翘提取物0.02%、紫荆皮提取物0.02%、黄芩提取物0.02%、板蓝根提取物0.02%；
止痛类中药B类:白芷提取物0.02%、花椒提取物0.02%、丁香提取物0.02%、芒硝提取物0.02%、硼砂提取物0.02%；
清新口气类中药C类:冰片提取物0.02%、薄荷提取物0.02%；
辅料为三乙醇胺、二烷基硫酸钠1.0％-3.0％、余量为纯净水。
本实施案例中，石膏提取物、芒硝提取物、硼砂提取物为水提物；紫花地丁提取物、金银花提取物、紫荆皮提取物、黄芩提取物、板蓝根提取物、花椒提取物为70%乙醇提物；连翘提取物为水蒸气蒸馏法提取物与70%乙醇提取物混合提取物，混合比例为1:1；丁香提取物为水蒸气蒸馏法提取物。
实施例5
本发明根据A、B、C三类中药的添加量的多少，设计三因素两水平的正交设计，每组设置三个重复，也就是实施例1-4，招募12名有一定口腔问题(均患有牙周炎)的志愿者三餐后使用漱口水，连续使用10天。表1中1表示中药添加量均取0.01%，2表示中药添加量均取0.04%。
Figure 500241DEST_PATH_IMAGE001
功效评价
使用漱口水连续十天后，对使用者进行问卷调查使用效果，结果如下：
Figure 682960DEST_PATH_IMAGE002
由实验结果分析可得，漱口水中清热解毒、止痛的药物添加量多少对牙龈肿痛、牙结石等问题影响明显，而清新口气的药物添加量对口气改善程度的影响不明显，从经济利益的角度出发，可减少清新口气的药物用量。中药漱口水患者使用前后口腔照片如图1所示，总体来讲，在较短的时间内，本发明的漱口水对牙周炎患者有较好的治疗作用。

Claims (5)

1.一种中药漱口水，其特征在于所述中药漱口水由以下重量配比的原料制成：石膏提取物0.03%-0.05%、紫花地丁提取物0.01%-0.05%、金银花提取物0.01%-0.05%、连翘提取物0.01%-0.05%、紫荆皮提取物0.01%-0.05%、黄芩提取物0.01%-0.05%、板蓝根提取物0.01%-0.05%等；白芷提取物0.01%-0.05%、花椒提取物0.01%-0.05%、丁香提取物0.01%-0.05%、芒硝提取物0.01%-0.05%、硼砂提取物0.01%-0.05%；冰片提取物0.01%-0.05%、薄荷提取物0.01%-0.05%；辅料为三乙醇胺、二烷基硫酸钠1.0％-3.0％、余量为纯净水。
2.根据权利要求1所述的一种中药漱口水，其特征在于：所述石膏提取物、芒硝提取物、硼砂提取物为水提物。
3.根据权利要求1所述的一种中药漱口水，其特征在于：所述紫花地丁提取物、金银花提取物、紫荆皮提取物、黄芩提取物、板蓝根提取物、花椒提取物为70%乙醇提物。
4.根据权利要求1所述的一种中药漱口水，其特征在于：所述连翘提取物为水蒸气蒸馏法提取物与70%乙醇提取物混合提取物。
5.根据权利要求1所述的一种中药漱口水，其特征在于：所述丁香提取物为水蒸气蒸馏法提取物。
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