CN105596784A - 一种治疗牙周炎的中药组合物 - Google Patents

一种治疗牙周炎的中药组合物 Download PDF

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CN105596784A
CN105596784A CN201610087063.4A CN201610087063A CN105596784A CN 105596784 A CN105596784 A CN 105596784A CN 201610087063 A CN201610087063 A CN 201610087063A CN 105596784 A CN105596784 A CN 105596784A
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孙茂志
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Abstract

本发明涉及一种治疗牙周炎的中药组合物，其中药原料及重量份配比为：旱莲草10-30份、骨碎补5-25份、龙葵5-20份、红花菜10-30份、木耳5-25份、石斛5-25份、寒水石5-25份、白芨5-20份、漏芦5-25份、风轮菜5-25份、穿山甲5-20份、地榆5-25份、凤尾草5-25份、槐花5-20份、龟板5-25份、石膏5-20份、黄珠子草5-25份、荠菜5-20份、龙船花5-25份、番泻叶5-20份、佩兰5-20份、三七5-25份、山豆根5-25份、甘草5-15份。本发明的中药组合物具有滋肾潜阳、益胃生津、补气养血、滋阴降火、消肿排脓、凉血止血的功效，其治疗牙周炎疗效显著，作用可靠。

Description

一种治疗牙周炎的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医药配制品，尤其是一种治疗牙周炎的中药组合物。
背景技术
牙周炎是侵犯牙龈和牙周支持组织的慢性破坏性疾病，其主要特征为牙周袋形成和袋壁的炎症，牙槽骨吸收和牙齿松动，同时伴见牙龈红肿出血等症状。治疗牙周炎，西医多采用口服抗菌消炎药物和局部牙周手术以及局部上药等。如果单用消炎药物，常常不能取得令人满意的效果，尤其是全身用药会产生较多的不良反应，如口服甲硝唑会引起皮疹、过敏反应、胃肠道刺激、恶心呕吐等症状。
牙周炎属于中医“牙宣”、“齿衄”、“齿挺”、“齿动摇”、“齿豁”范畴。病位在齿龈，与胃脾肾大肠等脏腑关系密切，过食辛辣炙博、酗酒过食或房劳太过等可致胃火上蒸，消齿灼龈；或肾阴亏虚，虚火上炎，灼伤牙龈而发为本病；久病致气血两虚，则齿失濡养，齿失润泽而见齿牙松动，牙龈萎缩等症。
根据中医理论，针对牙周炎的发病机理，采用滋肾潜阳、益胃生津、补气养血、滋阴降火、消肿排脓、凉血止血的治法，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中治疗牙周炎存在的不足，本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗牙周炎的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗牙周炎的中药组合物，其特征在于：其中药原料及重量份配比为：旱莲草10-30份、骨碎补5-25份、龙葵5-20份、红花菜10-30份、木耳5-25份、石斛5-25份、寒水石5-25份、白芨5-20份、漏芦5-25份、风轮菜5-25份、穿山甲5-20份、地榆5-25份、凤尾草5-25份、槐花5-20份、龟板5-25份、石膏5-20份、黄珠子草5-25份、荠菜5-20份、龙船花5-25份、番泻叶5-20份、佩兰5-20份、三七5-25份、山豆根5-25份、甘草5-15份。
本发明的优选技术方案是：一种治疗牙周炎的中药组合物，其特征在于：其中药原料及重量份配比为：旱莲草20份、骨碎补15份、龙葵10份、红花菜20份、木耳15份、石斛15份、寒水石15份、白芨10份、漏芦15份、风轮菜15份、穿山甲10份、地榆15份、凤尾草15份、槐花10份、龟板15份、石膏10份、黄珠子草15份、荠菜10份、龙船花15份、番泻叶10份、佩兰10份、三七15份、山豆根15份、甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：旱莲草具有养肝益肾、凉血止血的功效；骨碎补具有补肾强骨、续伤止痛的功效；龙葵具有清热解毒、利水消肿的功效；红花菜具有清热解毒、祛风明目、凉血止血的功效；木耳具有补气养血、润肺止咳的功效；石斛具有益胃生津、滋阴清热的功效；寒水石具有清热降火、利窍消肿的功效；白芨具有收敛止血、消肿生肌的功效；漏芦具有清热解毒、消肿排脓、下乳、通筋脉的功效；风轮菜具有疏风清热、解毒消肿、止血的功效；穿山甲具有活血通络、消肿排脓、祛风止痛、通乳的功效；地榆具有凉血止血、清热解毒、消肿敛疮的功效；凤尾草具有清热利湿、凉血止血、消肿解毒的功效；槐花具有凉血止血、清肝泻火的功效；龟板具有滋肾潜阳、益肾健骨、养血补心的功效；石膏具有清热泻火、除烦止渴的功效；黄珠子草具有健脾消积、利尿通淋、清热解毒的功效；荠菜具有凉肝止血、平肝明目、清热利湿的功效；龙船花具有清热凉血、散瘀止痛的功效；番泻叶具有泻热行滞、通便利水的功效；佩兰具有芳香化湿、醒脾开胃、发表解暑、辟秽和中的功效；三七具有活血祛淤、止血、消肿止痛的功效；山豆根具有清热解毒、消肿利咽的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明精选药物组方，其药物组分经辩证配伍，在作用上相互佐助，共奏滋肾潜阳、益胃生津、补气养血、滋阴降火、消肿排脓、凉血止血的功效，对牙周炎的治疗达到标本兼治。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。本发明遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著可靠，药性平和，未出现毒副作用，有效率达95%，治愈率76%。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1
一种治疗牙周炎的中药组合物，其中药原料及重量配比为：旱莲草20g、骨碎补15g、龙葵10g、红花菜20g、木耳15g、石斛15g、寒水石15g、白芨10g、漏芦15g、风轮菜15g、穿山甲10g、地榆15g、凤尾草15g、槐花10g、龟板15g、石膏10g、黄珠子草15g、荠菜10g、龙船花15g、番泻叶10g、佩兰10g、三七15g、山豆根15g、甘草10g。
实施例2
一种治疗牙周炎的中药组合物，其中药原料及重量配比为：旱莲草15g、骨碎补20g、龙葵5g、红花菜25g、木耳10g、石20g、寒水石5g、白芨15g、漏芦10g、风轮菜20g、穿山甲5g、地榆25g、凤尾草10g、槐花20g、龟板5g、石膏15g、黄珠子草10g、荠菜20g、龙船花5g、番泻叶15g、佩兰12g、三七20g、山豆根5g、甘草8g。
实施例3
一种治疗牙周炎的中药组合物，其中药原料及重量配比为：旱莲草25g、骨碎补5g、龙葵15g、红花菜10g、木20g、石斛5g、寒水石25g、白芨12g、漏20g、风轮5g、穿山甲5g、地榆10g、凤尾草20g、槐花5g、龟25g、石膏12g、黄珠子草20g、荠菜5g、龙船25g、番泻叶12g、佩兰20g、三七5g、山豆根25g、甘草12g。
实施例4
一种治疗牙周炎的中药组合物，其中药原料及重量配比为：旱莲草10g、骨碎补25g、龙葵12g、红花菜30g、木耳5g、石斛25g、寒水石10g、白芨20g、漏芦5g、风轮菜25g、穿山甲12g、地榆20g、凤尾草5g、槐花15g、龟板10g、石膏20g、黄珠子草5g、荠菜15g、龙船花10g、番泻叶20g、佩兰5g、三七25g、山豆根10g、甘草15g。
实施例5
一种治疗牙周炎的中药组合物，其中药原料及重量配比为：旱莲草30g、骨碎补10g、龙葵20g、红花菜15g、木耳25g、石斛10g、寒水石20g、白芨5g、漏芦25g、风轮菜10g、穿山甲20g、地榆5g、凤尾草25g、槐花12g、龟板20g、石膏5g、黄珠子草25g、荠菜12g、龙船花20g、番泻叶5g、佩兰15g、三七10g、山豆根20g、甘草5g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约6厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约4厘米，水沸后煎煮15～20分钟。两次煎煮取汁，合并。
本发明以实施例1所给出的一种治疗牙周炎的中药组合物，做临床疗效总结如下：
一、一般性资料：本中药组合物应用于临床观察病例100例，男53例，女47例，年龄15～65岁。
二、诊断依据：
1、以牙龈出血或龈齿间溢脓，牙齿松动，影响咬嚼为主要症状；
2、缓慢起病，逐渐加重，严重者发展为全口牙齿松动。病程中可有急性发作的牙周脓肿，局部红肿热痛，脓液量多，伴有发热；
3、口腔检查：牙龈红肿或萎缩，易出血，牙根宣露，牙齿松动。牙齿上附着牙垢、牙石；龈齿间有逐渐扩大的牙周袋，袋内溢脓。有口臭；
4、牙根周围X线片，示牙槽嵴吸收、牙间隙增宽等表现。
三、用法用量：临床应用时，一日一剂，水煎两遍取汁约400ml，分早、晚两次空腹温服。五天为一疗程。治疗期间忌生冷辛辣刺激之物。
四、疗效标准：
1、治愈：症状及体征消失，牙周袋小于4mm；
2、有效：症状和体征部分消失或减轻；
3、无效：症状和体征无明显变化。
五、治疗效果：该临床观察病例中，服药2-5个疗程，痊愈76例，随访未见复发；有效19例，无效5例。治疗期间未发生毒副作用。
六、典型病例：
病例1：
钱某，男，29岁。1周前突发出现牙痛、出血，近日来疼痛有所加重，影响饮食。检查：牙龈颜色暗红，质地松软，点彩消失，牙龈水肿，边缘圆钝，牙周袋均大于4mm，刷牙或进食时出血，咀嚼无力，口臭口苦，喜冷饮，大便秘结，舌质红，苔黄厚，脉洪大或滑数。诊断为:牙周炎。服用本发明中药组合物制备的药剂2个疗程，疼痛得到缓解，刷牙或进食时不再；继续服用2个疗程，所有症状完全消失，痊愈。随访半年未复发。
病例2：
刘某，女，43岁。主诉牙龈肿胀2周，刷牙出血，经服用甲硝唑、消炎痛1周效果不佳。诊见：牙龈出血痕迹、水肿、以门牙两侧牙龈为重，色泽呈紫色。服用本发明中药组合物制备的药剂1个疗程，出血及牙龈肿胀明显减轻；继续服用2个疗程，临床症状完全消失，痊愈。

Claims (2)

1.一种治疗牙周炎的中药组合物，其特征在于：其中药原料及重量份配比为：旱莲草10-30份、骨碎补5-25份、龙葵5-20份、红花菜10-30份、木耳5-25份、石斛5-25份、寒水石5-25份、白芨5-20份、漏芦5-25份、风轮菜5-25份、穿山甲5-20份、地榆5-25份、凤尾草5-25份、槐花5-20份、龟板5-25份、石膏5-20份、黄珠子草5-25份、荠菜5-20份、龙船花5-25份、番泻叶5-20份、佩兰5-20份、三七5-25份、山豆根5-25份、甘草5-15份。
2.根据权利要求1所述一种治疗牙周炎的中药组合物，其特征在于：其中药原料及重量份配比为：旱莲草20份、骨碎补15份、龙葵10份、红花菜20份、木耳15份、石斛15份、寒水石15份、白芨10份、漏芦15份、风轮菜15份、穿山甲10份、地榆15份、凤尾草15份、槐花10份、龟板15份、石膏10份、黄珠子草15份、荠菜10份、龙船花15份、番泻叶10份、佩兰10份、三七15份、山豆根15份、甘草10份。
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