CN112426495A - Ointment for treating hand joint diseases and preparation method thereof - Google Patents

Ointment for treating hand joint diseases and preparation method thereof Download PDF

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Publication number
CN112426495A
CN112426495A CN202011523954.2A CN202011523954A CN112426495A CN 112426495 A CN112426495 A CN 112426495A CN 202011523954 A CN202011523954 A CN 202011523954A CN 112426495 A CN112426495 A CN 112426495A
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powder
main material
ointment
material component
auxiliary material
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佟颖
宋佳愔
韩国鑫
付桐
邵忠林
张伟平
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Heilongjiang University of Chinese Medicine
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Heilongjiang University of Chinese Medicine
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
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Abstract

An ointment for treating hand joint diseases and a preparation method thereof belong to the traditional Chinese medicine and the preparation technology; the ointment is composed of main material components and auxiliary material components, wherein the main material components comprise asarum, garden balsam stem, radix aconiti, semen plantaginis, notopterygium root, rhizoma atractylodis, coix seed, lycopodium clavatum, radix paeoniae alba, ground beetle, ephedra, ligusticum wallichii, safflower, oleander, guava leaf, Chinese torreya seed, guava, nutmeg, gallnut, hypericum japonicum, acanthopanax, adiantum fischeriana, caper fruit, chaga, red powder, myrtle, podocarpus macrophyllus and Pinggu planch, and the auxiliary material components are alum jelly; mixing and processing main material mixed powder and auxiliary material powder obtained by processing main materials and auxiliary materials in a reaction kettle to obtain a pasty medicine finished product; the ointment is an external medicine, is used for relieving and treating hand joint swelling and pain and morning stiffness, has the characteristics of good treatment effect, small toxic and side effect, simplicity and convenience in use and simple preparation method, and can particularly meet and adapt to patients with gastrointestinal discomfort, weak constitution and inapplicability to oral medicines.

Description

Ointment for treating hand joint diseases and preparation method thereof
Technical Field
The invention belongs to a traditional Chinese medicine preparation and a preparation technology, and mainly relates to a medicine for treating rheumatoid diseases of hand joints.
Background
Rheumatoid arthritis is a systemic autoimmune disease mainly caused by symmetric multiple joints and small joint diseases, is a disease which has high disability rate and seriously affects the working capacity, the living capacity and the life quality of a patient, takes red swelling and hot pain of joints, morning stiffness and the like as clinical symptoms at the late stage, is mainly caused in joint parts such as hands, feet and the like, and has seriously damaged functions. The synovial membrane of the joint is continuously in a long-time abrasion state, so that an organism generates inflammatory reaction, a plurality of inflammatory cells infiltrate and damage cartilage and bone tissues, finally, the hand joint is deformed and the function is lost, and the life quality of a patient is seriously influenced. Since most patients alternate between attacks and remissions, long-term administration of drugs is required to alleviate and control the condition. The treatment adopts oral drugs for long-term administration, has great toxic and side effects and long administration time, and causes drug-induced irreversible damage to the liver and the kidney. The infrared physiotherapy has the problems of high specialty and poor flexibility, and a patient needs to go back and forth in a hospital for a long time. In addition, the existing hot compress product of pure traditional Chinese medicine powder has application, but the curative effect is poor.
Disclosure of Invention
The invention aims to solve the problems in the prior art, and researches and designs a hand joint disease treatment ointment with a multi-component formula by combining with the actual requirements on treatment and use of hand joint diseases caused by rheumatoid arthritis, so as to achieve the purposes of good pain relieving curative effect, small toxic and side effects and convenience and flexibility in use.
The purpose of the invention is realized as follows:
the ointment for treating hand joint diseases comprises a main material component and an auxiliary material component; the main material component comprises 5g of asarum, 30g of garden balsam stem, 30g of monkshood, 30g of plantain seed, 10g of notopterygium root, 15g of rhizoma atractylodis, 30g of coix seed, 30g of lycopodium clavatum, 20g of white peony root, 10g of eupolyphaga, 10g of ephedra, 30g of ligusticum wallichii and 30g of safflower, and the auxiliary material component comprises 300g of alum vaseline; the main material components also comprise 10g of oleander, guava leaf, Chinese torreya, guayule, nutgall, hypericum japonicum, acanthopanax, camptotheca acuminate, caper, inonotus obliquus, red powder, myrtle, Japanese pine and Japanese ardisia.
The preparation method of the ointment for treating hand joint diseases comprises the following steps: firstly, processing main materials: uniformly mixing all the components in the main material component into powder components obtained by respectively removing impurities, cleaning, drying, crushing and filtering with a 100-mesh sieve to obtain main material mixed powder; ② processing auxiliary materials: crushing the alum threne of the auxiliary material component, and filtering the crushed alum threne by using a 60-mesh sieve to obtain auxiliary material powder; ③ preparing by mixing: adding 50% of the adjuvant powder into a reaction kettle, stirring at 60-65 deg.C, slowly adding the main material mixed powder, stirring for 30min, slowly adding the rest adjuvant powder, and continuously stirring for 18-22min to obtain pasty medicinal product.
The main materials of the invention have the following effects:
1. asarum: pungent and warm herbs enter heart, lung and kidney meridians, and they can relieve exterior syndrome, dispel cold, expel wind, alleviate pain, induce resuscitation, warm lung and resolve retained fluid.
2. Garden balsam stem: warm in nature, tuberculate speranskia herb has effects of dispelling pathogenic wind, eliminating dampness, relaxing muscles and tendons, promoting blood circulation, and relieving pain; it is indicated for arthralgia due to wind-dampness, contraction of muscles and bones, cold-dampness, beriberi, sore, tinea and swelling.
3. Radix aconiti: light smell, pungent and numb tongue with strong toxicity, which enters heart, liver, kidney and spleen meridians. Has the effects of dispelling wind, eliminating dampness, warming channels and relieving pain, and is clinically used for treating anemofrigid-damp arthralgia, arthralgia and other diseases.
4. Plantain seed: sweet and cold in nature, it enters lung, kidney and liver meridians. Induce diuresis to treat stranguria, excrete dampness to stop diarrhea, clear liver and improve vision, clear lung heat and resolve phlegm. Can be used for treating stranguria with urine, summer damp diarrhea, phlegm heat cough, etc.
5. Notopterygium root: expelling wind and cold, eliminating dampness and alleviating pain.
6. Rhizoma atractylodis: dry dampness and invigorate spleen, dispel wind-damp.
7. Coix seed: sweet and light taste, slightly cold in nature; has the functions of invigorating spleen, promoting diuresis, clearing heat, expelling pus, warming spleen and stomach, dispelling cold, and invigorating qi and blood.
8. B, common clubmoss herb: it enters liver, kidney and spleen channels, and has the effects of dispelling pathogenic wind and cold, removing dampness and detumescence, relaxing muscles and tendons, promoting blood circulation, and treating internal cold and damp arthralgia, numbness of skin, weakness of limbs, edema, and traumatic injury. A
9. White peony root: bitter, sour and slightly cold, entering liver and spleen meridians, can nourish blood, regulate menstruation, soften liver, alleviate pain, astringe yin, check sweating and suppress liver yang. A
10. B, ground beetle: has the effects of removing blood stasis, dredging channels, and treating fracture, and can be used for treating female menostasis, galactostasis, fracture of tendons and bones, and swelling and pain due to blood stasis.
11. Herba ephedrae: ephedra, herba Ephedrae, of Celanding nature, called as the herb of Hu Lang, has the actions of relieving exterior syndrome with pungent and warm natured drugs, relieving asthma of lung, inducing diuresis to alleviate edema, and is clinically indicated for wind-cold type common cold, asthma, cough and edema.
12. Ligusticum wallichii: pungent and warm herbs enter liver, gallbladder and pericardium meridians, and can activate blood and move qi, dispel wind and alleviate pain, and they are combined with xi Xin to warm and dredge meridians, move qi and activate blood, so as to dispel cold, dispel wind, activate blood and alleviate pain. When used together with Bai Shao, it can strengthen the actions of moving qi, soothing liver and calming liver.
13. Safflower: promoting blood circulation, removing blood stasis, relieving swelling and pain.
14. Oleander: has effects in promoting blood circulation, relieving swelling, relieving itching, and killing parasite, and can be used for treating rheumatism, scabies, traumatic injury, sore, etc.
15. Guava leaf: has mild property, sweet and astringent taste, and has effects of astringing, relieving diarrhea, relieving inflammation, and stopping bleeding.
16. Chinese torreya seeds: sweet in nature and neutral in nature, they enter lung, stomach and large intestine meridians. Has the effects of killing parasites, removing food retention, moistening lung, relieving cough, moistening dryness and relaxing bowels. The traditional Chinese medicine composition is mainly used for treating ancylostomiasis, ascariasis, taeniasis, abdominal pain due to parasitic infestation, infantile malnutrition, cough due to lung dryness, constipation and other diseases in clinic.
17. And (3) odd willow: has effects of dispelling pathogenic wind, relieving exterior syndrome, promoting eruption and removing toxic substance, and can be used for treating wind-heat type common cold, early stage measles, and impenetrable eruption.
18. Nutgall: has the effects of astringing intestine, arresting spontaneous emission, relieving cough, stopping bleeding, and healing sore.
19. Herba Hyperici Japonici: sweet taste, slight bitter taste and cool nature, has the effects of clearing heat, promoting diuresis and removing toxicity, and is mainly used for treating infectious hepatitis, dysentery, infantile convulsion, malnutritional stagnation, tonsillitis, intestinal carbuncle, furuncle, snake flood wound and the like.
20. Acanthopanax root: has the efficacies of replenishing qi to invigorate the spleen, tonifying the kidney and soothing the nerves, and has obvious anti-fatigue effect clinically.
21. Rhizome of Botrychium argenteum: has sweet and mild nature and taste, and has effects of suppressing hyperactive liver, clearing heat, relieving cough and clearing pathogenic fire, improving eyesight, removing toxic substance and dispelling pathogenic wind.
22. Mountain orange: has the effects of dispelling wind, relieving exterior syndrome, eliminating phlegm, relieving cough, regulating qi, removing food stagnation, removing blood stasis and relieving swelling. Can be used for treating common cold, cough, food stagnation, anorexia, abdominal pain due to dyspepsia, hernia pain, and swelling and pain due to traumatic injury.
23. And (3) Inonotus obliquus: has effects in clearing away heat and toxic materials, regulating qi, promoting blood circulation, dispersing pathogen accumulation, invigorating qi, and nourishing yin, and can be used for treating gastritis, dyspepsia, emesis, diarrhea, constipation, etc.
24. Red powder: tranquilizing mind, killing bacteria, removing toxic substances, removing necrotic tissue, and promoting granulation.
25. And (3) myrtle: has effects in nourishing blood, stopping bleeding, astringing intestine, arresting spontaneous emission, removing dampness, and relieving diarrhea.
26. And (3) podocarpus macrophyllus: it is indicated for heart and stomach pain, blood deficiency and sallow complexion and tonifying primordial qi.
27. Flat ground wood: birch phlegm can relieve cough, promote diuresis, and promote blood circulation, and can be used for treating chronic cough, bloody phlegm, jaundice, edema, stranguria, leucorrhea, amenorrhea, dysmenorrhea, rheumatalgia, traumatic injury, and testis swelling and pain.
The invention makes full use of and exerts the effects of the components in the main material components, mutually promotes and synergistically treats the main material components through the organic combination of the components, further increases and improves the functions and treatment effects of the components, has the characteristics of pain relieving, good anti-inflammation effect, small toxic and side effect, simple and convenient use, simple preparation method, joint deformity prevention and skin maintenance, and simultaneously, because the invention is an external medicine, the toxic and side effect of the oral medicine is avoided, the invention has no stimulation to the digestive system of a patient, and particularly can meet and adapt to the patients with gastrointestinal discomfort, weak constitution and inapplicability to the oral medicine, and the invention can be used by the patients in all seasons.
Detailed Description
The embodiments of the present invention are described in detail below.
An ointment for treating hand joint diseases, which consists of a main material component and an auxiliary material component; the main material component comprises 5g of asarum, 30g of garden balsam stem, 30g of monkshood, 30g of plantain seed, 10g of notopterygium root, 15g of rhizoma atractylodis, 30g of coix seed, 30g of lycopodium clavatum, 20g of white peony root, 10g of eupolyphaga, 10g of ephedra, 30g of ligusticum wallichii and 30g of safflower, and the auxiliary material component comprises 300g of alum vaseline; the main material components also comprise 10g of oleander, guava leaf, Chinese torreya, guayule, nutgall, hypericum japonicum, acanthopanax, camptotheca acuminate, caper, inonotus obliquus, red powder, myrtle, Japanese pine and Japanese ardisia.
The preparation method of the ointment for treating hand joint diseases comprises the following steps: firstly, processing main materials: uniformly mixing all the components in the main material component into powder components obtained by respectively removing impurities, cleaning, drying, crushing and filtering with a 100-mesh sieve to obtain main material mixed powder; ② processing auxiliary materials: crushing the alum threne of the auxiliary material component, and filtering the crushed alum threne by using a 60-mesh sieve to obtain auxiliary material powder; ③ preparing by mixing: adding 50% of the adjuvant powder into a reaction kettle, stirring at 60-65 deg.C, slowly adding the main material mixed powder, stirring for 30min, slowly adding the rest adjuvant powder, and continuously stirring for 18-22min to obtain pasty medicinal product.
When in use, the ointment is applied to the joints of hands, gradually permeates into the body through the skin of the hands, enters the focus of infection and is absorbed, thereby relieving and treating symptoms of swelling and pain of the hands, morning stiffness and the like of a patient, gradually relieving the pain of the malformation of the hands of the patient and improving the mobility.

Claims (2)

1. An ointment for treating hand joint diseases, which consists of a main material component and an auxiliary material component; the main material component comprises 5g of asarum, 30g of garden balsam stem, 30g of monkshood, 30g of plantain seed, 10g of notopterygium root, 15g of rhizoma atractylodis, 30g of coix seed, 30g of lycopodium clavatum, 20g of white peony root, 10g of eupolyphaga, 10g of ephedra, 30g of ligusticum wallichii and 30g of safflower, and the auxiliary material component comprises 300g of alum vaseline; the method is characterized in that: the main material components also comprise 10g of oleander, guava leaf, Chinese torreya, guayule, nutgall, hypericum japonicum, acanthopanax, camptotheca acuminate, caper, inonotus obliquus, red powder, myrtle, Japanese pine and Japanese ardisia.
2. A method for preparing the ointment for treating hand joint diseases according to claim 1, which is characterized in that: the method comprises the following steps: firstly, processing main materials: uniformly mixing all the components in the main material component into powder components obtained by respectively removing impurities, cleaning, drying, crushing and filtering with a 100-mesh sieve to obtain main material mixed powder; ② processing auxiliary materials: crushing the alum threne of the auxiliary material component, and filtering the crushed alum threne by using a 60-mesh sieve to obtain auxiliary material powder; ③ preparing by mixing: adding 50% of the adjuvant powder into a reaction kettle, stirring at 60-65 deg.C, slowly adding the main material mixed powder, stirring for 30min, slowly adding the rest adjuvant powder, and continuously stirring for 18-22min to obtain pasty medicinal product.
CN202011523954.2A 2020-12-10 2020-12-10 Ointment for treating hand joint diseases and preparation method thereof Pending CN112426495A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058689A (en) * 2009-11-17 2011-05-18 宋振河 Externally-applied traditional Chinese medicine for treating arthritis
CN104189127A (en) * 2014-09-22 2014-12-10 马良志 Joint analgesia ointment and preparation method thereof
CN107050151A (en) * 2017-06-23 2017-08-18 杨玉荣 The network that relaxes plays old cream and preparation method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058689A (en) * 2009-11-17 2011-05-18 宋振河 Externally-applied traditional Chinese medicine for treating arthritis
CN104189127A (en) * 2014-09-22 2014-12-10 马良志 Joint analgesia ointment and preparation method thereof
CN107050151A (en) * 2017-06-23 2017-08-18 杨玉荣 The network that relaxes plays old cream and preparation method

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Application publication date: 20210302