CN104706749A - Traditional Chinese medicine composition for treating lumbar intervertebral disc protrusion - Google Patents
Traditional Chinese medicine composition for treating lumbar intervertebral disc protrusion Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating lumbar intervertebral disc protrusion. The traditional Chinese medicine composition is prepared from the following active pharmaceutical ingredients in parts by weight: 280-320 parts of geranium wilfordii, 280-320 parts of pyrola, 180-220 parts of radix clematidis, 180-220 parts of achyranthes bidentata, 280-320 parts of rhizoma corydalis, 180-220 parts of cassia twig, 180-220 parts of angelica sinensis, 280-320 parts of radix angelicae, 180-220 parts of radix angelicae pubescentis, 180-220 parts of borneol and 40-80 parts of camphor. The traditional Chinese medicine composition has a scientific and reasonable formula, the efficacy directly arrives to the affected part, and the traditional Chinese medicine composition can quickly ease the pain and has the advantages of fast effect, no toxic or side effect and low cost.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of lumbar vertebra shoulder disc protrusion, belong to technical field of traditional Chinese medicine preparation.
Background technology
Prolapse of lumbar intervertebral disc belongs to motherland's medical science it " lumbago ", " arthromyodynia " category.It occurs and caused by liver and kidney deficiency, and the outer wind-cold damp pathogen that injures of strain is invaded closely related.At present, clinical treatment is still based on non-operative treatment, and the massage extensively adopted, massage, Epidural, chemical dissolve the non-operative treatments such as vertebral pulp, the self-regulating function of most neglect patients, thus late result is not good enough, and after intervertebral disk hernia, local vertebral body is unstable, facet joint tropism, outthrust is oppressed, then there will be local blood circulation obstacle, tissue edema, not normal and the aseptic inflammation of metabolism, still on western medical treatment adopts Drug therapy and operative treatment more.But the negative concern being more and more subject to people of chemicals and operative treatment thereof, western medical treatment can only relief of symptoms, and has obvious side effect, and perform the operation expensive, long-term effect can not be affirmed; Treatment by Chinese herbs side effect is less, but current all kinds of Chinese medicine still can not rapid recovery patient pain, and take effect comparatively slow, patient suffering is larger.
Summary of the invention
For the deficiency that above-mentioned prior art exists, the object of this invention is to provide a kind of Chinese medicine composition for the treatment of lumbar vertebra shoulder disc protrusion, this Traditional Chinese medicine composition formula is scientific and reasonable, and the efficacy of a drug is gone directly affected part, can quick pain relief, there is instant effect, have no side effect, low cost and other advantages.
For achieving the above object, the present invention adopts following technical proposals:
Treating a Chinese medicine composition for lumbar vertebra shoulder disc protrusion, is be made up of the crude drug of following weight portion:
Herba Erodii 280 ~ 320 parts, Herba Pyrolae 280 ~ 320 parts, Radix Clematidis 180 ~ 220 parts, Radix Achyranthis Bidentatae 180 ~ 220 parts, Rhizoma Corydalis 280 ~ 320 parts, Ramulus Cinnamomi 180 ~ 220 parts, Radix Angelicae Sinensis 180 ~ 220 parts, the Radix Angelicae Dahuricae 280 ~ 320 parts, Radix Angelicae Pubescentis 180 ~ 220 parts, Borneolum Syntheticum 80 ~ 120 parts, Camphora 40 ~ 80 parts.
Preferably, the Chinese medicine composition of this treatment lumbar vertebra shoulder disc protrusion is made up of the crude drug of following weight portion:
Herba Erodii 300 parts, Herba Pyrolae 300 parts, Radix Clematidis 200 parts, Radix Achyranthis Bidentatae 200 parts, Rhizoma Corydalis 300 parts, Ramulus Cinnamomi 200 parts, Radix Angelicae Sinensis 200 parts, the Radix Angelicae Dahuricae 300 parts, Radix Angelicae Pubescentis 200 parts, Borneolum Syntheticum 100 parts, Camphora 60 parts.
The preparation method of Chinese medicine composition of the present invention, pulverizes each crude drug, crosses 200 mesh sieves, mixes.
During treatment; get powdery Chinese medicine composition of the present invention; in 1g medicated powder with mixed liquor 1ml (white rice vinegar/medicinal glycerin by volume 3:1 proportional arrangement becomes mixed liquor) ratio furnishing pasty state; paving equably needs a 2g and piece 8cm × 12cm to need on the adhesive plaster of 3g at 2 pieces (8cm × 8cm) square every block; 1cm immobilization with adhesive tape is stayed in edge; non-textile mulch medicine; the subsides either side of the small of the back cave of side; the long perpendicular row in spinal column direction of pressing pastes A Si cave; sticking 24 hours; once a day, 7 days is a course for the treatment of.The general same day or second day take effect, and can cure after continuous 2 courses for the treatment of.Further, during treatment, adopt Chinese medicine keritherapy to coordinate above-mentioned external application for curing, effect is better.
Chinese medicine composition of the present invention further can make oral formulations or external preparation with one or more pharmaceutically acceptable adjuvants, can be tablet, pill, capsule or unguentum.
Adjuvant is selected from calcium phosphate, magnesium stearate, Pulvis Talci, dextrin, starch, gelatinous fibre element, methylcellulose, sanlose, polyvinylpyrrolidone, one or more in white rice vinegar and glycerol.
The Chinese medicine composition for the treatment of lumbar vertebra shoulder disc protrusion of the present invention, the property of medicine of each taste crude drug is as follows:
Herba Erodii: pungent, bitter, flat, tepor.Enter liver,kidney,spleen,bladder warp.Wind-damp dispelling, dredges through invigorating blood circulation, muscle reinforcing and bone strengthening.Heat-clearing and toxic substances removing, antidiarrheal dysentery.
Herba Pyrolae: nature and flavor: sweet, bitter, temperature.Enter lung meridian, stomach warp, Liver Channel, kidney channel.Wind-damp dispelling, bone and muscle strengthening, hemostasis, cough-relieving.Energy tonify deficiency, kidney tonifying, expelling wind and removing dampness, promoting blood flow to regulate menstruation, the kidney invigorating bone strengthening, expelling wind and removing dampness, cough-relieving, hemostasis.Cure mainly: main lumbago due to renal deficiency, rheumatic arthralgia, soft, the new chronic cough of muscles and bones flaccidity are coughed, spit blood, epistaxis, metrorrhagia, traumatic hemorrhage.
Radix Clematidis: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant is loose long-pending; Cure mainly anemofrigid-damp arthralgia, chills and pain of the waist and kness, numb limbs and tense tendons, muscles and bones pulsation contracture.
Radix Achyranthis Bidentatae: bitter, sweet, sour is flat, nontoxic.Enter the heart, liver, large intestine three warp.Promoting blood circulation to remove blood stasis, damp eliminating diuresis, heat-clearing and toxic substances removing.Control gonorrhea, hematuria, women's amenorrhea, lump in the abdomen, rheumatic arthritis, beriberi, edema, dysentery, malaria, diphtheria, carbuncle, traumatic injury.
Ramulus Cinnamomi: pungent; Sweet; Warm in nature, nontoxic.Enter bladder, the heart, lung meridian.Expelling cold and relieving exterior syndrome; Promoting the flow of QI-blood by warming the meridian; Activating YANG and prormoting functioning of QI.Main exterior syndrome due to wind-cold; Arthralgia due to cold-dampnes; Extreme cold of the limbs; Amenorrhea dysmenorrhea; Lump in the abdomen lumps; The thoracic obstruction; Cardiopalmus; Phlegm retention; Dysuria.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Rhizoma Corydalis: pungent, bitter, temperature.GUIXIN, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.
The Radix Angelicae Dahuricae: pungent, temperature.Return lung, stomach, large intestine channel.Induce sweat cold expelling, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Radix Angelicae Pubescentis: arduous, temperature.Enter kidney, urinary bladder channel.Dispel the wind, victory is wet, cold expelling, pain relieving.Control anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.
Borneolum Syntheticum: the effect having refreshment of having one's ideas straightened out, swells and ache for skin infection, does not hold back after bursting.The merit of clearing away heat to alleviate pain, detumescence.
Camphora: Gui Jing: the heart; Spleen channel effect: orifice opening; Qi stagnation removing; Ward off foul; Killing parasites for relieving itching; Reducing swelling and alleviating pain.
Chinese medicine composition of the present invention, in side, rigorous, the dialectical logic of each medicine compatibility is careful, with Herba Erodii, Herba Pyrolae be monarch's expelling wind and removing dampness, channels sootheing and network vessel quickening, analgesic therapy of invigorating blood circulation, removing stasis to stop bleeding control its arthromyodynia; Herba Erodii and Radix Angelicae Pubescentis, the equal tool of two medicines is pungent, bitter, using warming therapy, function wind-damp dispelling, and pain relieving, induces sweat, and cures mainly rheumatic arthralgia.Its difference is Radix Angelicae Pubescentis dispelling the wind and dampness pathogens, is suitable with the arthromyodynia of bottom.Therefore lumbago and skelalgia, two flaccidity of the lower limbs numbness can not be walked, and belong to person caused by cold-damp, and this product is often held as key medicine.And Herba Erodii is all effective to the rheumatism arthromyodynia of whole body, join Radix Clematidis, Radix Clematidis is pungent, and temperature, wind-damp dispelling, the meridian dredging, stopping numbness pain, also can use dispelling the wind and dampness pathogens arthralgia pain.The monarch and his subjects two medicine compatibility, mutual reinforcement between uses, and makes the meridian dredging, wind-damp dispelling, and analgesic effect strengthens, and is aided with Radix Angelicae Sinensis, Rhizoma Corydalis with blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain; Help with Ramulus Cinnamomi, the Radix Angelicae Dahuricae with promoting blood circulation to remove blood stasis, circulation of qi promoting relaxing muscles and tendons; Dispersing wind-cold, warming the meridian and promoting blood circulation.Each medicine synergism, plays effect of tendons relaxing and meridians dredging, blood circulation promoting and blood stasis dispelling altogether, to treatment of lumbar disc herniation Be very effective.
Beneficial effect of the present invention:
(1) Chinese medicine composition compatibility of the present invention is reasonable, and external application is by local application, and the efficacy of a drug is gone directly focus, and effect is concentrated, can pain relief fast, has instant effect, has no side effect, low cost and other advantages.
(2) external application of Chinese medicine of the present invention adds Chinese medicine keritherapy treatment is heat energy after utilizing medicine to heat and the effect of medicine itself, and have double effects, Chinese medicine used has the effect of promoting blood circulation to remove obstruction in the collateral, expelling wind and removing dampness; Heat energy can make skin mucosa hyperemia expansion, and the effective ingredient of medicine can be penetrated in joint tissue; Both synergism can accelerate the circulation of local blood and lymph fluid, alleviate the vein stasis of blood stagnant, reduce intraosseous pressure, alleviating pain and swelling, thus reach the effect improving intervertebral disc function.Heat is row then, cold then coagulate, and play temperature three-way meridian, blood circulation promoting and blood stasis dispelling, the effect of anti-inflammatory analgesic, curative effect is very remarkable.
Detailed description of the invention
Below by instantiation, the present invention will be further elaborated, should be noted that following explanation is only to explain the present invention, not limiting its content.
Embodiment 1: a kind of Chinese medicine composition for the treatment of lumbar vertebra shoulder disc protrusion
Formula: Herba Erodii 280 grams, Herba Pyrolae 280 grams, Radix Clematidis 180 grams, Radix Achyranthis Bidentatae 180 grams, Rhizoma Corydalis 280 grams, Ramulus Cinnamomi 180 grams, Radix Angelicae Sinensis 180 grams, the Radix Angelicae Dahuricae 280 grams, Radix Angelicae Pubescentis 180 grams, Borneolum Syntheticum 80 grams, Camphora 40 grams.
Preparation method: cross 200 mesh sieves after crude drug each in formula being ground into fine powder, mixing.
Using method: get above-mentioned mixed powder, in 1g medicated powder with mixed liquor 1ml (white rice vinegar/medicinal glycerin by volume 3:1 proportional arrangement becomes mixed liquor) ratio furnishing pasty state, paving equably needs a 2g and piece 8cm × 12cm to need on the adhesive plaster of 3g at 2 pieces (8cm × 8cm) square every block, 1cm immobilization with adhesive tape is stayed in edge, non-textile mulch medicine, the subsides either side of the small of the back cave of side, the long perpendicular row in spinal column direction of pressing pastes A Si cave.
Embodiment 2: a kind of Chinese medicine composition for the treatment of lumbar vertebra shoulder disc protrusion
Formula: Herba Erodii 300 grams, Herba Pyrolae 300 grams, Radix Clematidis 200 grams, Radix Achyranthis Bidentatae 200 grams, Rhizoma Corydalis 300 grams, Ramulus Cinnamomi 200 grams, Radix Angelicae Sinensis 200 grams, the Radix Angelicae Dahuricae 300 grams, Radix Angelicae Pubescentis 200 grams, Borneolum Syntheticum 100 grams, Camphora 60 grams.
Preparation method, using method, with embodiment 1, repeat no more.
Embodiment 3: a kind of Chinese medicine composition for the treatment of lumbar vertebra shoulder disc protrusion
Formula: Herba Erodii 320 grams, Herba Pyrolae 320 grams, Radix Clematidis 220 grams, Radix Achyranthis Bidentatae 220 grams, Rhizoma Corydalis 320 grams, Ramulus Cinnamomi 220 grams, Radix Angelicae Sinensis 220 grams, the Radix Angelicae Dahuricae 320 grams, Radix Angelicae Pubescentis 220 grams, Borneolum Syntheticum 120 grams, Camphora 80 grams.
Preparation method, using method, with embodiment 1, repeat no more.
Embodiment 4: a kind of Chinese medicine composition for the treatment of lumbar vertebra shoulder disc protrusion
Formula: Herba Erodii 290 grams, Herba Pyrolae 290 grams, Radix Clematidis 190 grams, Radix Achyranthis Bidentatae 190 grams, Rhizoma Corydalis 290 grams, Ramulus Cinnamomi 190 grams, Radix Angelicae Sinensis 190 grams, the Radix Angelicae Dahuricae 290 grams, Radix Angelicae Pubescentis 190 grams, Borneolum Syntheticum 90 grams, Camphora 50 grams.
Preparation method, using method, with embodiment 1, repeat no more.
Embodiment 5: a kind of Chinese medicine composition for the treatment of lumbar vertebra shoulder disc protrusion
Formula: Herba Erodii 310 grams, Herba Pyrolae 310 grams, Radix Clematidis 210 grams, Radix Achyranthis Bidentatae 210 grams, Rhizoma Corydalis 310 grams, Ramulus Cinnamomi 210 grams, Radix Angelicae Sinensis 210 grams, the Radix Angelicae Dahuricae 310 grams, Radix Angelicae Pubescentis 210 grams, Borneolum Syntheticum 110 grams, Camphora 70 grams.
Preparation method, using method, with embodiment 1, repeat no more.
Clinical data:
1.1 physical data are verify the curative effect of Chinese medicine composition of the present invention, collect total cases 120 example altogether, wherein man 68 example, female 52 example; 44 ~ 72 years old age, average 58 years old; L
4-5outstanding person 58 example, L
5-S
1outstanding person 42 example, L
3-S
1outstanding person 24 example simultaneously, the course of disease is the longest 15 years, the shortest February.
1.2 diagnostic criterias formulate diagnostic criteria with reference to the diagnostic criteria of prolapse of lumbar intervertebral disc in " disease of tcm Standardization of diagnosis and curative effect ", and curved flank pain radiates to lower limb; There is pressure pain point local; Straight-leg raising test is positive; Dermal sensation muscular strength and tendon reflex change; Spine posture changes; CT or MR-CT prompting has intervertebral disk hernia.
1.3 methods: this is organized 120 examples and be divided into 3 groups at random, are respectively treatment I group 40 example, treatment II group 40 example, matched group 40 example.The processing method of each group is as follows:
1.3.1 treat I group 40cm × 60cm disposable mat wax bag (20cm × 40cm silica gel packed 2000ml liquid wax is placed in 60 calorstats for subsequent use) is wrapped up, avoid scalding, bag puts Chinese medicine bag and (is made into 15cm × 20cm medicated bag, in-built 0.5 thick Chinese medicine powder, the same application compress of medicine, spilling mixed liquor (white rice vinegar/medicinal glycerin by volume 3:1 proportional arrangement become) makes medicine moist, spreads on painful area, sticks Chinese medicine patch again after 40 minutes time.
The making of Chinese medicine patch; get mixed powder prepared by the embodiment of the present invention 2; in 1g medicated powder with mixed liquor 1ml (white rice vinegar/medicinal glycerin by volume 3:1 proportional arrangement becomes mixed liquor) ratio furnishing pasty state; paving equably needs a 2g and piece 8cm × 12cm to need on the adhesive plaster of 3g at 2 pieces (8cm × 8cm) square every block; 1cm immobilization with adhesive tape is stayed in edge; non-textile mulch medicine; the subsides either side of the small of the back cave of side; the long perpendicular row in spinal column direction of pressing pastes A Si cave; sticking 24 hours; once a day, 7 days is a course for the treatment of, continuous 2 courses for the treatment of.
1.3.2 treat II group in same area external application with the Chinese medicine for the treatment of I group same composition but without Chinese medicine keritherapy, application time is with treatment I group.
1.3.3 matched group matched group is at same area external application " pain can be pasted " externally applied ointment (doctor's hall is appointed in Beijing), and application time is with treatment I group.
1.4 criterions of therapeutical effect are evaluated with reference to " disease of tcm Standardization of diagnosis and curative effect ".
Cure: lumbago and skelalgia transference cure, waist movable function are normal, Negative straight-leg raising test, energy normal activity and work, follow up a case by regular visits to 1 year without recurrence.
Effective: lumbago and skelalgia symptom obviously alleviates, waist movable function is normal, and straight-leg raising test ﹥ 70 °, can recover normal activity and work,
Take a turn for the better: lumbago and skelalgia symptom alleviates, waist movable function obviously improves before comparatively treating, and straight-leg raising test ﹥ 60 °, life can be taken care of oneself.
Invalid: subjective symptoms and function are without improvement.
2 therapeutic outcomes
Therapeutic outcome in table 1, as can be seen from Table 1: treatment group is evident in efficacy is better than matched group (P < 0.05), has statistical significance between two groups;
Table 1 three groups of therapeutic effect compare
| Group | Number of cases | Cure (example) | Effective (example) | Effectively (example) | Invalid (example) | Total effective rate (%) |
| Treatment I group | 40 | 13 | 16 | 10 | 1 | 97.5 |
| Treatment II group | 40 | 10 | 14 | 12 | 4 | 90 |
| Matched group | 40 | 6 | 12 | 14 | 8 | 80 |
As can be seen from Table 1, treatment I group and treatment II group all achieve excellent curative effect, and compared with matched group, therapeutic effect significantly improves.Treatment I group curative effect is better than treatment II group, visible, adopts wax therapy to coordinate the effect of external application for curing to be better than and adopts external application for curing merely.The present inventor also observes in long-term clinical course, and simple drug application treatment, all exists limitation in various degree, and wax therapy adds drug application R. concomitans between the two, then can significantly improve general curative effect, not only there is satisfied short term effect, also have good late result.Inventor observes in long-term clinical course, and simple drug application treatment, all exists limitation in various degree, and R. concomitans between the two, then can significantly improve general curative effect, not only there is satisfied short term effect, also have good late result.Also can find from our clinical research, comprehensive treatment is all significantly better than simple drug application group on cure rate and effective percentage, compares, have significant difference through statistics.
As can be seen here, Chinese medicine composition scientific formula of the present invention is reasonable, and during treatment, the efficacy of a drug can be gone directly affected part, quick pain relief, has instant effect, has no side effect, low cost and other advantages.
Claims (5)
1. treat a Chinese medicine composition for lumbar vertebra shoulder disc protrusion, it is characterized in that, be made up of the crude drug of following weight portion:
Herba Erodii 280 ~ 320 parts, Herba Pyrolae 280 ~ 320 parts, Radix Clematidis 180 ~ 220 parts, Radix Achyranthis Bidentatae 180 ~ 220 parts, Rhizoma Corydalis 280 ~ 320 parts, Ramulus Cinnamomi 180 ~ 220 parts, Radix Angelicae Sinensis 180 ~ 220 parts, the Radix Angelicae Dahuricae 280 ~ 320 parts, Radix Angelicae Pubescentis 180 ~ 220 parts, Borneolum Syntheticum 80 ~ 120 parts, Camphora 40 ~ 80 parts.
2. as claimed in claim 1 a kind of treat lumbar vertebra shoulder disc protrusion Chinese medicine composition, it is characterized in that, be made up of the crude drug of following weight portion:
Herba Erodii 300 parts, Herba Pyrolae 300 parts, Radix Clematidis 200 parts, Radix Achyranthis Bidentatae 200 parts, Rhizoma Corydalis 300 parts, Ramulus Cinnamomi 200 parts, Radix Angelicae Sinensis 200 parts, the Radix Angelicae Dahuricae 300 parts, Radix Angelicae Pubescentis 200 parts, Borneolum Syntheticum 100 parts, Camphora 60 parts.
3. the preparation method of the Chinese medicine composition of the treatment lumbar vertebra shoulder disc protrusion described in claim 1 or 2, it is characterized in that, by Herba Erodii, Herba Pyrolae, Radix Clematidis, Radix Achyranthis Bidentatae, Rhizoma Corydalis, Ramulus Cinnamomi, Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Radix Angelicae Pubescentis, Borneolum Syntheticum and Camphora, pulverize, sieve, mix and get final product.
4. treat a Chinese medicine preparation for lumbar vertebra shoulder disc protrusion, it is characterized in that, make oral formulations or external preparation by Chinese medicine composition according to claim 1 and one or more pharmaceutically acceptable adjuvants.
5. as claimed in claim 4 a kind of treat lumbar vertebra shoulder disc protrusion Chinese medicine preparation, it is characterized in that, described adjuvant is calcium phosphate, magnesium stearate, Pulvis Talci, dextrin, starch, gelatinous fibre element, methylcellulose, sanlose, polyvinylpyrrolidone, one or more in white rice vinegar and glycerol.
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Cited By (2)
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| CN105168681A (en) * | 2015-07-20 | 2015-12-23 | 冉宇欣 | Medicine for treating lumbar disc herniation with syndrome of blood stasis and preparation method of medicine |
| CN107281384A (en) * | 2016-04-07 | 2017-10-24 | 范付春 | A kind of Chinese medicine preparation for treating disc herniation |
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| CN102125672A (en) * | 2010-01-12 | 2011-07-20 | 姚玉健 | Traditional Chinese medicine for treating cervical and lumbar spinal diseases and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168681A (en) * | 2015-07-20 | 2015-12-23 | 冉宇欣 | Medicine for treating lumbar disc herniation with syndrome of blood stasis and preparation method of medicine |
| CN107281384A (en) * | 2016-04-07 | 2017-10-24 | 范付春 | A kind of Chinese medicine preparation for treating disc herniation |
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