CN112424609A - 卒中的血液生物标志物 - Google Patents

卒中的血液生物标志物 Download PDF

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Publication number
CN112424609A
CN112424609A CN201980047566.0A CN201980047566A CN112424609A CN 112424609 A CN112424609 A CN 112424609A CN 201980047566 A CN201980047566 A CN 201980047566A CN 112424609 A CN112424609 A CN 112424609A
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China
Prior art keywords
stroke
leu
ala
subject
sample
Prior art date
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Pending
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CN201980047566.0A
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English (en)
Chinese (zh)
Inventor
S·坦西
E·格宁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
French Blood Institution
Institut National de la Sante et de la Recherche Medicale INSERM
Univerdite de Bretagne Occidentale
CHU DE BREST
Original Assignee
French Blood Institution
Institut National de la Sante et de la Recherche Medicale INSERM
Univerdite de Bretagne Occidentale
CHU DE BREST
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Publication date
Application filed by French Blood Institution, Institut National de la Sante et de la Recherche Medicale INSERM, Univerdite de Bretagne Occidentale, CHU DE BREST filed Critical French Blood Institution
Publication of CN112424609A publication Critical patent/CN112424609A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201980047566.0A 2018-05-16 2019-05-16 卒中的血液生物标志物 Pending CN112424609A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18305600 2018-05-16
EP18305600.1 2018-05-16
PCT/EP2019/062653 WO2019219831A1 (en) 2018-05-16 2019-05-16 Blood biomarkers of stroke

Publications (1)

Publication Number Publication Date
CN112424609A true CN112424609A (zh) 2021-02-26

Family

ID=62386311

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980047566.0A Pending CN112424609A (zh) 2018-05-16 2019-05-16 卒中的血液生物标志物

Country Status (13)

Country Link
US (1) US12247257B2 (https=)
EP (1) EP3794355A1 (https=)
JP (2) JP7463351B2 (https=)
KR (1) KR20210049026A (https=)
CN (1) CN112424609A (https=)
AU (1) AU2019270404B2 (https=)
BR (1) BR112020023259A2 (https=)
CA (1) CA3100171A1 (https=)
IL (1) IL278666B2 (https=)
MA (1) MA52617A (https=)
MX (1) MX2020012297A (https=)
SG (1) SG11202011369VA (https=)
WO (1) WO2019219831A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116705296A (zh) * 2023-06-06 2023-09-05 中国科学院深圳先进技术研究院 一种基于常规mri序列对gbm患者进行风险分层的方法及系统

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220093267A1 (en) * 2019-01-22 2022-03-24 Arizona Board Of Regents On Behalf Of The University Of Arizona Noninvasive real-time patient-specific assessment of stroke severity
CN114107487B (zh) * 2021-12-23 2024-01-09 太原市精神病医院 一种可用于诊断脑卒中的产品
JP2023111774A (ja) * 2022-01-31 2023-08-10 国立研究開発法人国立循環器病研究センター 再灌流療法の適用を決定するバイオマーカー
WO2025151599A1 (en) * 2024-01-09 2025-07-17 Morehouse School Of Medicine Rna-based method for stroke assessment and treatment

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030104393A1 (en) * 2000-11-28 2003-06-05 Sharp Frank R. Blood assessment of injury
WO2015054700A2 (en) * 2013-10-13 2015-04-16 The Research Foundation For Suny Biomarkers for predicting risk of acute ischemic stroke and methods of use thereof
WO2018067571A2 (en) * 2016-10-03 2018-04-12 West Virginia University Computer implemented discovery of biomarkers for blood brain barrier disruption
CN108291330A (zh) * 2015-07-10 2018-07-17 西弗吉尼亚大学 卒中和卒中严重性的标志物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US9005891B2 (en) 2009-11-10 2015-04-14 Genomic Health, Inc. Methods for depleting RNA from nucleic acid samples
US9410204B2 (en) 2012-01-07 2016-08-09 The Regents Of The University Of California Biomarkers for diagnosing ischemia
US20150274815A1 (en) * 2012-09-25 2015-10-01 The United States of America, as represented by the Secretary, Department of Health & Human Servic Treatment of central nervous system (cns) injury
JP2016507235A (ja) * 2013-02-01 2016-03-10 ウエストバージニア ユニバーシティＷｅｓｔ Ｖｉｒｇｉｎｉａ Ｕｎｉｖｅｒｓｉｔｙ 脳卒中症状の発症の時点を決定するためのバイオマーカーアルゴリズムおよび方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030104393A1 (en) * 2000-11-28 2003-06-05 Sharp Frank R. Blood assessment of injury
WO2015054700A2 (en) * 2013-10-13 2015-04-16 The Research Foundation For Suny Biomarkers for predicting risk of acute ischemic stroke and methods of use thereof
CN108291330A (zh) * 2015-07-10 2018-07-17 西弗吉尼亚大学 卒中和卒中严重性的标志物
WO2018067571A2 (en) * 2016-10-03 2018-04-12 West Virginia University Computer implemented discovery of biomarkers for blood brain barrier disruption

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
胡智祥: "《医院临床检验技术操作规范与实（化）验室管理全书（第一卷）》", 银声音像出版社, pages: 110 - 113 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116705296A (zh) * 2023-06-06 2023-09-05 中国科学院深圳先进技术研究院 一种基于常规mri序列对gbm患者进行风险分层的方法及系统
CN116705296B (zh) * 2023-06-06 2024-09-13 中国科学院深圳先进技术研究院 一种基于常规mri序列对gbm患者进行风险分层的方法及系统

Also Published As

Publication number Publication date
MA52617A (fr) 2021-03-24
KR20210049026A (ko) 2021-05-04
EP3794355A1 (en) 2021-03-24
AU2019270404B2 (en) 2025-04-17
SG11202011369VA (en) 2020-12-30
AU2019270404A2 (en) 2020-12-17
IL278666B1 (en) 2025-02-01
US20210214793A1 (en) 2021-07-15
JP2021523744A (ja) 2021-09-09
AU2019270404A1 (en) 2020-12-10
MX2020012297A (es) 2021-03-25
JP2024075761A (ja) 2024-06-04
IL278666A (en) 2020-12-31
BR112020023259A2 (pt) 2021-02-23
US12247257B2 (en) 2025-03-11
JP7463351B2 (ja) 2024-04-08
CA3100171A1 (en) 2019-11-21
WO2019219831A1 (en) 2019-11-21
IL278666B2 (en) 2025-06-01

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