CN112423687A - 用于促进新的骨组织的形成的装置 - Google Patents

用于促进新的骨组织的形成的装置 Download PDF

Info

Publication number
CN112423687A
CN112423687A CN201980045841.5A CN201980045841A CN112423687A CN 112423687 A CN112423687 A CN 112423687A CN 201980045841 A CN201980045841 A CN 201980045841A CN 112423687 A CN112423687 A CN 112423687A
Authority
CN
China
Prior art keywords
lower portion
formation
promoting
upper portion
bone tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980045841.5A
Other languages
English (en)
Inventor
邓肯·惠特韦尔
阿德里安·泰勒
本·肯德里克
德伯勒·希格斯
马克·法尔沃尔斯
马克斯·吉本斯
汤姆·科斯克
迈克·帕里
乔纳森·史蒂文森
安迪·约翰斯通
斯科特·萨默维尔
卢克·约翰松
理查德·博伊尔
戈登·布伦恩
索罗蒙·达迪亚
帕诺斯·伊卡斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
I Itos Pharmaceutical Co ltd
Adler Alto Ag
Original Assignee
I Itos Pharmaceutical Co ltd
Adler Alto Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by I Itos Pharmaceutical Co ltd, Adler Alto Ag filed Critical I Itos Pharmaceutical Co ltd
Publication of CN112423687A publication Critical patent/CN112423687A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72Intramedullary pins, nails or other devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2/2814Bone stump caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30721Accessories
    • A61F2/30724Spacers for centering an implant in a bone cavity, e.g. in a cement-receiving cavity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A61F2002/30064Coating or prosthesis-covering structure made of biodegradable material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30112Rounded shapes, e.g. with rounded corners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30205Three-dimensional shapes conical
    • A61F2002/3021Three-dimensional shapes conical frustoconical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30205Three-dimensional shapes conical
    • A61F2002/30217Three-dimensional shapes conical hollow cones, e.g. tubular-like cones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/30233Stepped cylinders, i.e. having discrete diameter changes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30721Accessories
    • A61F2/30734Modular inserts, sleeves or augments, e.g. placed on proximal part of stem for fixation purposes or wedges for bridging a bone defect
    • A61F2002/30738Sleeves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30784Plurality of holes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/3092Special external or bone-contacting surface, e.g. coating for improving bone ingrowth having an open-celled or open-pored structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/3093Special external or bone-contacting surface, e.g. coating for improving bone ingrowth for promoting ingrowth of bone tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2002/30985Designing or manufacturing processes using three dimensional printing [3DP]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00592Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Prostheses (AREA)

Abstract

一种用于促进新的骨组织的形成的装置(1),该装置包括本体,该本体限定上部部分(2)和下部部分(3),该下部部分(3)具有基本上平截头体状的形状,上部部分(2)具有基本上圆柱形的形状,下部部分适于插入骨的髓管中。

Description

用于促进新的骨组织的形成的装置
本发明涉及一种用于促进新的骨组织的形成的装置。更具体地,本发明涉及一种装置,该装置可以使新的骨组织从可用的骨组织的量非常小的状况开始再生。
众所周知,人类骨骼由骨和关节组成。由久坐的生活方式引起的体重增加、年龄增加等均导致诸如关节病的疾病更普遍。
因此,创造了人工关节,假体被插入在两个骨部件之间以替代自然关节。最初,使用粘固剂进行假体和两个骨部件之间的结合。后来,使用无粘固剂的关节假体,其中人工关节由骨传导材料和覆盖物制成。特定类别的人工假体以用于“重大灾难”的假体为代表:这些假体是用于癌症患者或用于为了全面检查先前假体而经历多次介入的患者的假体。在这两种情况下,可用的骨组织的量显著减少。
通常在无粘固剂的假体中,努力将假体与骨之间的接触面积增大到最大值。在用于“重大灾难”的假体中,除了寻求最大的接触面积之外,还致力于满足纤维软骨性骨痂的要求。
充当修复组织的纤维软骨性骨痂是在创伤(如去除受肿瘤影响的骨组织)或骨折后出现的常见状况。创伤事件后大约四周,骨痂的第一征候(即,所形成的新组织)使两个断端愈合,并且随着时间的推移,该骨痂响应于施加在其上的机械力而变化,逐渐变得越来越坚固和耐用。
具体地,存在外围发育的骨膜骨痂和在骨髓腔中形成的骨内骨痂。
本发明的目标是提供一种用于促进新的骨组织的形成的装置,该装置可以被插入骨的髓管中。
在此目标内,本发明的一个目的是提供一种用于促进新的骨组织的形成的装置,该装置有利于在外部形成骨膜骨痂和在内部形成骨内骨痂。
本发明的另一个目的是提供一种在可用的骨组织的量非常小的状况下用于促进新的骨组织的形成的装置。
本发明的另一个目的是提供一种用于促进新的骨组织的形成的装置,该装置可以用于身体的任何解剖部位中。
本发明的另一个目的是提供一种用于促进新的骨组织的形成的装置,该装置高度可靠、实施容易且实用并且成本低。
在下文中将变得更明显的这个目标以及这些和其他目的是通过一种用于促进新的骨组织的形成的装置来实现的,该装置的特征是包括本体,该本体限定了上部部分和下部部分,所述下部部分具有基本上平截头体的形状,所述上部部分具有基本上圆柱形的形状,所述下部部分适于插入骨的髓管中。
从对根据本发明的装置的优选但非排他性的实施例的描述中,本发明的其他特征和优点将变得更加显而易见,所述实施例在附图中以非限制性实例的方式示出,在附图中:
图1是根据本发明的装置的俯视立体图;
图2是根据本发明的装置的仰视立体图;
图3是根据本发明的装置的侧视图;
图4是根据本发明的装置的仰视平面图;
图5是根据本发明的装置的俯视平面图;
图6是根据本发明的装置沿着线VI-VI截取的截面图;
图7是根据本发明的装置沿着线VII-VII截取的截面图。
参考附图,根据本发明的装置(总体上由参考标号1表示)包括上部部分2和下部部分3。下部部分3与上部部分2之间的区别是为了指示适于插入骨的髓管中的部分(下部部分),从而将该部分与适于从髓管突出的上部部分2区分开。
有利地,根据本发明的装置被构造为具有顶部开口4和底部开口5的内部中空的本体。
方便地,根据本发明的装置的下部部分3为平截头体形状,以允许插入到髓管中。相反,上部部分2被制成基本上圆柱形或圆锥形的形状。
这不仅促进骨膜骨痂(在上部部分处)的形成而且促进骨内骨痂(在平截头体形状的下部部分处)的形成,从而克服了已知技术的限制。
方便地,上部部分2通过弯曲区段6与下部部分3接合。
有利地,中空的上部部分2内部轮廓呈朝向本体的轴线的阶梯的方式,以便从上向下(即,从上部部分2朝向下部部分3)限定第一阶梯8以及第二阶梯11,该第一阶梯通过弯曲部分将第一上部部分9连接到第二上部部分10,该第二阶梯将第二上部部分10连接到下部部分3的内表面12。
下部部分3的内表面12是圆柱形的。
顶部开口4方便地成形有由两个弯曲区段15和16连接的直的且平行的两个区段。
根据本发明的装置是通过从钛合金粉末或铬-钴钼合金粉末、特别适合于促进骨再生的材料开始的增材技术而提供的。
通过这样的技术和这样的材料,可以获得能够促进新的骨组织的形成的多孔外表面。
根据本发明的装置适于定位在可用骨的残余部分的顶端,并且利用两种类型的纤维软骨性骨痂,即:
-在外部骨与根据本发明的装置的上部部分2(圆柱形或圆锥形)之间形成的外部(骨膜)纤维软骨性骨痂;
-在根据本发明的装置的下部部分3(平截头体形)(该下部部分插入骨的髓管中)与骨干腔的骨内骨之间形成的内部(骨内)纤维软骨性骨痂。
以此方式,通过根据本发明的装置实现了外部纤维软骨性骨痂与内部纤维软骨性骨痂之间的一种连接部分。
该装置能够实现高水平的骨结合,并且可以治疗由于骨的大量移除或由于多次全面检查介入而使得骨量非常低的那些患者。
由此设想的装置容许许多修改和变化,所有这些修改和变化都在所附权利要求的范围内。
此外,所有细节可以由其他技术上等同的元件代替。
实际上,所使用的材料以及视情况而定的形状和尺寸可以是根据要求和现有技术的任何材料。
本申请要求意大利专利申请第102018000007049号的优先权,其公开内容通过引证结合于此。
在任何权利要求中提及的技术特征后面伴有参考标号的情况下,这些参考标号被包括以用于增加权利要求的可理解性这一唯一目的,并且因此,这样的参考标号对由这样的参考标号通过示例的方式标识的每个元件的解释不具有任何限制作用。

Claims (8)

1.一种用于促进新的骨组织的形成的装置(1),其特征在于,所述装置包括本体,所述本体限定上部部分(2)和下部部分(3),所述下部部分(3)具有基本上平截头体状的形状,所述上部部分(2)具有基本上圆柱形的形状,所述下部部分(3)适于插入到骨的髓管中。
2.根据权利要求1所述的装置,其特征在于,所述上部部分(2)通过弯曲区段(6)与所述下部部分(3)接合。
3.根据权利要求1所述的装置,其特征在于,所述本体是具有顶部开口(4)和底部开口(5)的内部中空的本体。
4.根据权利要求1所述的装置,其特征在于,所述装置是通过粉末增材技术提供的。
5.根据权利要求1所述的装置,其特征在于,所述装置涂覆有羟基磷灰石。
6.根据前述权利要求中的一项或多项所述的装置,其特征在于,所述下部部分(3)和所述上部部分(2)具有多孔外表面,以促进骨结合。
7.根据前述权利要求中的一项或多项所述的装置,其特征在于,所述装置适于在人体的任何解剖部位中使用。
8.根据前述权利要求中的一项或多项所述的装置,其特征在于,所述下部部分(3)具有比所述上部部分(2)小的直径。
CN201980045841.5A 2018-07-10 2019-06-12 用于促进新的骨组织的形成的装置 Pending CN112423687A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT102018000007049 2018-07-10
IT201800007049 2018-07-10
PCT/EP2019/065400 WO2020011475A1 (en) 2018-07-10 2019-06-12 Device for facilitating the formation of new bone tissue

Publications (1)

Publication Number Publication Date
CN112423687A true CN112423687A (zh) 2021-02-26

Family

ID=63684344

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980045841.5A Pending CN112423687A (zh) 2018-07-10 2019-06-12 用于促进新的骨组织的形成的装置

Country Status (6)

Country Link
US (1) US11678990B2 (zh)
EP (1) EP3820390B1 (zh)
CN (1) CN112423687A (zh)
AU (1) AU2019300119B2 (zh)
IL (1) IL280001A (zh)
WO (1) WO2020011475A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12023253B2 (en) 2014-01-24 2024-07-02 Howmedica Osteonics Corp. Humeral implant anchor system
US10456264B2 (en) 2014-01-24 2019-10-29 Tornier, Inc. Humeral implant anchor system
US10463499B2 (en) 2016-03-25 2019-11-05 Tornier, Inc. Stemless shoulder implant with fixation components
US11129724B2 (en) 2016-07-28 2021-09-28 Howmedica Osteonics Corp. Stemless prosthesis anchor component
US11974925B2 (en) 2017-09-25 2024-05-07 Howmedica Osteonics Corp. Patient specific stemless prosthesis anchor components
JP7434538B2 (ja) 2019-10-01 2024-02-20 ハウメディカ オステオニクス コーポレイション 肩プロテーゼコンポーネント及び肩プロテーゼ組立体
USD951449S1 (en) * 2019-10-01 2022-05-10 Howmedica Osteonics Corp. Humeral implant

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1527741A1 (en) * 2003-10-31 2005-05-04 Orthofix International B.V. Insert for orthopaedic use
US20060167560A1 (en) * 2004-12-17 2006-07-27 Heck Robert K Modular implant system and method with diaphyseal implant and adapter
CN201822903U (zh) * 2010-07-02 2011-05-11 北京爱康宜诚医疗器材股份有限公司 皮质外骨桥固定假体
CN105380731A (zh) * 2015-10-15 2016-03-09 赵德伟 一种多孔钽金属骨连接器及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015682A1 (en) * 1992-02-14 1993-08-19 American Cyanamid Company Polymeric screws and coatings for surgical uses
FR2708461B1 (fr) * 1993-08-06 1995-09-29 Advanced Technical Fabrication Implant intersomatique pour colonne vertébrale.
US6783549B1 (en) * 2001-07-27 2004-08-31 Biomet, Inc. Modular humeral head resurfacing system
US8105388B2 (en) * 2002-10-24 2012-01-31 Biomet Manufacturing Corp. Method and apparatus for wrist arthroplasty
US7125423B2 (en) * 2003-03-31 2006-10-24 Depuy Products, Inc. Intercalary prosthesis, kit and method
US8926670B2 (en) * 2003-06-18 2015-01-06 Roger P. Jackson Polyaxial bone screw assembly
US8100982B2 (en) * 2004-12-17 2012-01-24 Depuy Products, Inc. Modular diaphyseal and collar implant
US9814583B2 (en) * 2007-05-08 2017-11-14 Zimmer, Inc. Modular stem extension
GB0720596D0 (en) 2007-10-22 2007-11-28 Smith & Nephew Joint prosthesis
EP2106767A1 (en) * 2008-03-31 2009-10-07 Ziterion GmbH Two-part dental implant
WO2009143374A2 (en) * 2008-05-23 2009-11-26 Novalign Orthopaedics, Inc. Modular segmented intramedullary system, apparatus and associated methods
US8998959B2 (en) * 2009-06-15 2015-04-07 Roger P Jackson Polyaxial bone anchors with pop-on shank, fully constrained friction fit retainer and lock and release insert
WO2012074991A1 (en) * 2010-11-30 2012-06-07 Amit Sinha Bone compression and fixation devices
WO2012128825A1 (en) * 2011-03-24 2012-09-27 Jackson Roger P Polyaxial bone anchor with compound articulation and pop-on shank
US8998996B2 (en) * 2012-09-20 2015-04-07 Depuy (Ireland) Knee prosthesis system with standard and distal offset joint line
US9566092B2 (en) * 2013-10-29 2017-02-14 Roger P. Jackson Cervical bone anchor with collet retainer and outer locking sleeve
WO2015134750A1 (en) * 2014-03-06 2015-09-11 University Of British Columbia Shape adaptable intramedullary fixation device
US9844440B2 (en) * 2014-08-14 2017-12-19 Biomet Manufacturing, Llc Glenoid implant
EP3282961A4 (en) * 2015-04-14 2018-12-05 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
KR101731542B1 (ko) * 2016-10-05 2017-05-02 주식회사 트루어버트먼트코리아 임플란트용 픽스쳐

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1527741A1 (en) * 2003-10-31 2005-05-04 Orthofix International B.V. Insert for orthopaedic use
US20060167560A1 (en) * 2004-12-17 2006-07-27 Heck Robert K Modular implant system and method with diaphyseal implant and adapter
CN201822903U (zh) * 2010-07-02 2011-05-11 北京爱康宜诚医疗器材股份有限公司 皮质外骨桥固定假体
CN105380731A (zh) * 2015-10-15 2016-03-09 赵德伟 一种多孔钽金属骨连接器及其应用

Also Published As

Publication number Publication date
AU2019300119A1 (en) 2021-02-04
US20210228362A1 (en) 2021-07-29
EP3820390B1 (en) 2024-07-31
AU2019300119B2 (en) 2022-06-09
WO2020011475A1 (en) 2020-01-16
EP3820390A1 (en) 2021-05-19
US11678990B2 (en) 2023-06-20
IL280001A (en) 2021-03-01

Similar Documents

Publication Publication Date Title
CN112423687A (zh) 用于促进新的骨组织的形成的装置
US4728335A (en) Hip prosthesis
EP2730254B1 (en) Dual modulus hip stem
JP4838731B2 (ja) 大腿骨股関節補綴具および移植方法
JP4152452B2 (ja) 人工器官の取付装置
US5725595A (en) Cannulated cementless hip stem prosthesis
US5376124A (en) Collared hip prosthesis with revision spacer
JP7112526B2 (ja) 指関節プロテーゼ及びその製造方法
JPH0236862A (ja) 関節人工器官のための関節ソケット部材
WO1990011739A1 (en) Joint prosthesis
JP6742913B2 (ja) 多層構造補綴要素
JP6016781B2 (ja) 股関節インプラント
JP2008531146A (ja) 表面再建股関節インプラントを構成するセット
JP6275437B2 (ja) 可変a/pテーパ角を用いた大腿骨ステムコンポーネントを有する整形外科用股関節プロテーゼ
JPH03500978A (ja) 人工腰関節およびその使用
JPH01153154A (ja) 股関節プロテーゼの大腿部
JP4568232B2 (ja) 人工骨頭保持具
TWI498111B (zh) 拇指腕掌關節人工植體
WO2015150347A1 (en) Endoprosthesis
CN109157309A (zh) 胫骨近端填充块假体
CN210019806U (zh) 一种人工关节铸件
US20150374499A1 (en) Femoral prosthesis with an absorbable shank
JPH09501064A (ja) 人工骨および人工骨移植方法
CN215130915U (zh) 一种四肢骨的重建装置
KR20200083730A (ko) 다중 다공성 구조를 가지는 임플란트 및 그 제작방법

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
CB03 Change of inventor or designer information

Inventor after: Deng Ken.huiteweier

Inventor after: Yasu

Inventor after: Scott Somerville

Inventor after: Lu Ke.yuehansong

Inventor after: Richard Boyle

Inventor after: Ge Deng.bulunen

Inventor after: Suo Luomeng.dadiya

Inventor after: Panos ICAS

Inventor after: A Delian.taile

Inventor after: Keyoku Toshikatsu

Inventor after: Deborah Higgs

Inventor after: Mark farworth

Inventor after: Ma Kesi.jibensi

Inventor after: Tang Mu.kesike

Inventor after: Mike Parry

Inventor after: Jonathan Stevenson

Inventor before: Deng Ken.huiteweier

Inventor before: Yasu

Inventor before: Scott Somerville

Inventor before: Lu Ke.yuehansong

Inventor before: Richard Boyle

Inventor before: Ge Deng.bulunen

Inventor before: Suo Luomeng.dadiya

Inventor before: Panos ICAS

Inventor before: A Delian.taile

Inventor before: Keyoku Toshikatsu

Inventor before: Deborah Higgs

Inventor before: Mark farworth

Inventor before: Ma Kesi.jibensi

Inventor before: Tang Mu.kesike

Inventor before: Mike Parry

Inventor before: Jonathan Stevenson

CB03 Change of inventor or designer information
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination