CN112402634A - Water bath sterilization temperature pressure water distribution system that evenly distributes - Google Patents
Water bath sterilization temperature pressure water distribution system that evenly distributes Download PDFInfo
- Publication number
- CN112402634A CN112402634A CN202011372941.XA CN202011372941A CN112402634A CN 112402634 A CN112402634 A CN 112402634A CN 202011372941 A CN202011372941 A CN 202011372941A CN 112402634 A CN112402634 A CN 112402634A
- Authority
- CN
- China
- Prior art keywords
- water
- pipe
- temperature
- sterilization
- distribution system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 286
- 230000001954 sterilising effect Effects 0.000 title claims abstract description 97
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 85
- 238000009826 distribution Methods 0.000 title claims abstract description 76
- 238000010438 heat treatment Methods 0.000 claims description 30
- 238000005057 refrigeration Methods 0.000 claims description 14
- 238000003860 storage Methods 0.000 claims description 9
- 230000001105 regulatory effect Effects 0.000 claims description 2
- 238000000151 deposition Methods 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 24
- 229940079593 drug Drugs 0.000 abstract description 12
- 238000005507 spraying Methods 0.000 abstract description 3
- 239000000126 substance Substances 0.000 abstract description 3
- 230000036512 infertility Effects 0.000 abstract description 2
- 230000000704 physical effect Effects 0.000 abstract 1
- 239000010410 layer Substances 0.000 description 10
- 238000000034 method Methods 0.000 description 9
- 238000001816 cooling Methods 0.000 description 5
- 239000000498 cooling water Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 239000011229 interlayer Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 238000001802 infusion Methods 0.000 description 3
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 238000007731 hot pressing Methods 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 239000008236 heating water Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/24—Apparatus using programmed or automatic operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/11—Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/14—Means for controlling sterilisation processes, data processing, presentation and storage means, e.g. sensors, controllers, programs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The invention discloses a water-bath sterilization temperature and pressure uniform water distribution system, and belongs to the technical field of medicine sterilization. The water-bath sterilization temperature and pressure uniform water distribution system comprises a sterilizer, wherein a sterilization cavity is arranged in the sterilizer; the sterilization frame is arranged in the sterilization cavity in a sliding mode; the water distribution system is arranged above the sterilization cavity and is used for spraying and sterilizing the products on the sterilization rack; the circulating water constant pressure system is arranged above the sterilizer and is connected with the water distribution system; the temperature equalizing device is arranged on the circulating water constant pressure system. By applying the water bath sterilization temperature and pressure uniform water distribution system provided by the invention, the medicines of one batch can be heated (cooled) more uniformly in the same time period, and the sterility level, the physical property and the chemical property of the product are consistent.
Description
Technical Field
The invention relates to the technical field of medicine sterilization, in particular to a water-bath sterilization temperature and pressure uniform water distribution system.
Background
The infusion is the most widely used in clinic and one of the most important treatment means, the liquid medicine directly enters the blood through the veins of the human body, and the aseptic level of the liquid medicine is of great importance to the medication safety of the human body. The sterility guarantee of the large infusion is usually realized by killing microorganisms, and the sterilization method mainly adopted in the large infusion industry is a hot-pressing sterilization method.
The method of heating water by steam or other media and killing the drug microorganisms by the superheated water under a certain pressure is the most common hot-pressing sterilization method, and has been widely adopted by the pharmaceutical industry due to the factors of the temperature uniformity, the temperature controllability, the economy of the media and the like of the water. The method of killing microbes using "superheated water" is known as a water bath sterilization method.
The water bath sterilization method has advantages over other sterilization methods due to the uniformity of temperature, the uniformity of temperature is relative in the actual drug sterilization process, drugs sterilized by using 'superheated water' in the same sterilizer also have different physical and chemical properties due to the difference of temperature, and the root causes of the different properties are mainly non-uniformity of water quantity of the drug shower and non-uniformity of water temperature.
This temperature difference is particularly significant for the sterilization quality of heat sensitive pharmaceuticals.
Disclosure of Invention
The invention aims to provide a water distribution system with uniform temperature and pressure for water bath sterilization, which aims to solve the technical problems in the background technology.
In order to achieve the purpose, the invention adopts the following technical scheme:
a water bath sterilization temperature and pressure uniform water distribution system comprises: the sterilizer is internally provided with a sterilization cavity; the sterilization frame is arranged in the sterilization cavity in a sliding mode; the water distribution system is arranged above the sterilization cavity and is used for spraying and sterilizing the products on the sterilization rack; the circulating water constant pressure system is arranged above the sterilizer and is connected with the water distribution system; the temperature equalizing device is arranged on the circulating water constant pressure system.
Further, water bath sterilization temperature pressure water distribution system still includes: a heating heat exchange device and a refrigerating heat exchange device which are respectively communicated with the temperature equalizing device.
Further, the water distribution system includes: the constant-pressure pipe in the cabinet is communicated with the water outlet end of the circulating water constant-pressure system; the plurality of the shunt tubes are connected to a constant-pressure tube in the cabinet at equal intervals; a water distribution plate: the water distribution disks are arranged at the top of the sterilization cavity, a water storage cavity is arranged in each water distribution disk, a plurality of first water leakage holes are formed in the bottom of the water storage cavity, and each water distribution disk corresponds to one flow division pipe; the check ring is arranged at the bottom of the water storage cavity, and the shunt pipe is arranged in the check ring.
Furthermore, the shunt tubes are U-shaped, the middle parts of the shunt tubes are connected to a constant-pressure tube in the cabinet, two retaining rings are arranged on each water distribution plate, two ends of each U-shaped shunt tube are respectively arranged in the retaining rings, and flow adjusting flower plates are respectively arranged at two ends of each shunt tube.
Further, the circulating water constant pressure system comprises: the inlet of the balance pipe is communicated with the water outlet of the temperature equalizing device; the water inlet of the constant pressure tank is communicated with the outlet of the balance pipe; the outer constant voltage pipe of cabinet, the delivery port and the outer constant voltage union coupling of cabinet of constant voltage jar, the outer constant voltage pipe of cabinet passes through the connecting pipe and the interior constant voltage union coupling of cabinet, the connecting pipe is sealed to set firmly on the lateral wall of sterilizer.
Furthermore, the balance pipe and the constant pressure tank are respectively provided with two parts which are respectively and symmetrically arranged at two sides of the temperature equalizing device; the pipe diameter of the balance pipe is arranged from large to small from one end far away from the constant pressure tank to one end close to the constant pressure tank.
Further, the temperature uniforming device includes: the temperature controllers are respectively arranged on the constant pressure tanks; the temperature balancing device is arranged on the balancing pipe; and the water outlet end of the water mixing pipe is respectively communicated with the water inlets of the two balance pipes.
Furthermore, the heating and heat exchanging device comprises a heating heat exchanger and a first water pump, wherein the water inlet end of the first water pump is communicated with the bottom of the sterilizer, the water outlet end of the first water pump is communicated with the water inlet of the heating heat exchanger, and the water outlet of the heating heat exchanger is connected with the water inlet end of the water mixing pipe.
Furthermore, the refrigeration heat exchange device comprises a refrigeration heat exchanger and a second water pump, wherein the water inlet end of the second water pump is communicated with the bottom of the sterilizer, the water outlet end of the second water pump is communicated with the water inlet of the refrigeration heat exchanger, and the water outlet of the refrigeration heat exchanger is connected with the water inlet end of the water mixing pipe.
Further, the sterilization rack includes: the sterilization box of a plurality of range upon range of settings, be equipped with in the sterilization box and place the chamber, the bottom of sterilization box is for having the cavity intermediate layer, a plurality of second holes that leak that run through are seted up to cavity interbedded roof, a plurality of third holes that leak that run through are seted up to cavity interbedded diapire, the aperture in second hole that leaks is greater than the aperture in third hole that leaks.
Compared with the prior art, the invention has the beneficial effects that:
according to the water-bath sterilization temperature and pressure uniform water distribution system provided by the invention, after circulating water is treated by the heating heat exchanger and the refrigerating heat exchanger, the temperature of water at the same moment is relatively uniform by the temperature uniform device, the flow velocity at the position of the minimum pipe diameter is ensured by the balance pipe with the gradually reduced pipe diameter, the water pressure in the constant-pressure tank is kept at constant pressure, the water pressure flowing into the flow dividing pipe is balanced and fixed after the pressure is balanced again by the secondary constant-pressure pipe (inside and outside the cabinet), and the fine adjustment of the flow adjusting flower disc at the water outlet end of the flow dividing pipe is carried out, so that the water flow of each flow dividing pipe flowing into the water distribution disc; meanwhile, the water temperature difference in each constant pressure tank can be adjusted through a temperature balancing device. Finally, the flow and the temperature of the circulating water flowing into the water distribution disc are uniform at the same time.
Circulating water flowing into the water distribution disc performs shower heating (cooling) on the medicines loaded in the sterilization box and arranged regularly through first water leakage holes with the same aperture uniformly distributed on the water distribution disc, the circulating water flowing through the surface of the medicines flows through second larger water leakage holes in the upper layer of the sterilization box to form liquid levels such as water distribution and the like in an interlayer of the sterilization box, and the medicines in the next layer are subjected to shower heating (cooling) through third smaller water leakage holes in the bottom layer of the sterilization box to finally realize that the medicines in a batch are heated (cooled) more uniformly in the same time period, and the products are sterile, level, physical and chemical properties consistent.
Drawings
FIG. 1 is a schematic view of a water bath sterilization temperature and pressure uniform water distribution system of the present invention.
Fig. 2 is a schematic structural diagram of a sterilization cavity of a water bath sterilization temperature and pressure uniform water distribution system of the invention.
FIG. 3 is a schematic connection diagram of a water distribution system and a circulating water constant pressure system of the water bath sterilization temperature and pressure uniform water distribution system of the present invention.
FIG. 4 is a schematic view of the connection between the water distribution disk and the retainer ring of the water bath sterilization temperature and pressure uniform water distribution system of the present invention.
Fig. 5 is a schematic connection diagram of a water distribution disk and a shunt pipe of the water bath sterilization temperature and pressure uniform water distribution system.
Fig. 6 is a schematic connection diagram of a flow regulating flower disc and a shunt pipe of the water bath sterilization temperature and pressure uniform water distribution system.
Fig. 7 is a schematic structural diagram of a sterilization box of a water bath sterilization temperature and pressure uniform water distribution system of the invention.
Fig. 8 is a test chart of the temperature uniformity of the water bath sterilization temperature and pressure uniform water distribution system of the invention by adopting a wireless verifier.
The labels in the figure are: 1-a sterilizer, 2-a heating heat exchanger, 3-a constant pressure tank, 4-a balance pipe, 5-an external constant pressure pipe, 6-a first water pump, 7-a refrigerating heat exchanger, 8-a water distribution disc, 9-a shunt pipe, 10-a temperature controller, 11-a temperature balancing device, 12-a water mixing pipe, 13-a flow adjusting flower disc, 14-a retainer ring, 15-a sterilizing cavity, 16-a sterilizing frame, 17-a medicine, 18-an internal constant pressure pipe, 19-an internal circulating water pipeline, 20-a second water pump, 21-a first water leakage hole, 22-a sterilizing box, 23-a second water leakage hole, 24-a third water leakage hole and 25-a hollow interlayer.
Detailed Description
The present invention will be further described with reference to the following examples, which are intended to illustrate only some, but not all, of the embodiments of the present invention. Based on the embodiments of the present invention, other embodiments used by those skilled in the art without any creative effort belong to the protection scope of the present invention.
Example 1:
as shown in fig. 1 and 2, a temperature and pressure uniform water distribution system for water bath sterilization comprises: the device comprises a sterilizer 1, a sterilization frame 16, a water distribution system, a circulating water constant pressure system, a temperature equalizing device, a heating heat exchange device and a refrigerating heat exchange device; a sterilization cavity 15 is arranged in the sterilizer 1; the sterilizing rack 16 is slidably arranged in the sterilizing cavity 15, and the sterilizing rack 16 is used for placing medicines 17 to be sterilized. The water distribution system is arranged above the sterilization cavity 15 and is used for spraying and sterilizing products on the sterilization rack 16; the circulating water constant pressure system is arranged above the sterilizer 1 and is connected with the water distribution system; the temperature equalizing device is arranged on the circulating water constant pressure system; the heating heat exchange device and the refrigerating heat exchange device are respectively communicated with the temperature equalizing device.
As shown in fig. 1 to 3, in this embodiment, the water distribution system includes: the device comprises an in-cabinet constant pressure pipe 18, a shunt pipe 9, a water distribution disc 8 and a retainer ring 14, wherein the in-cabinet constant pressure pipe 18 is communicated with the water outlet end of a circulating water constant pressure system; a plurality of the shunt tubes 9 are connected to a constant pressure tube 18 in the cabinet at equal intervals; the water distribution disks 8 are arranged at the top of the sterilization cavity 15, a water storage cavity is arranged in each water distribution disk 8, a plurality of first water leakage holes 21 are arranged at the bottom of the water storage cavity, the diameter of each first water leakage hole 21 is about 2mm, and each water distribution disk 8 is arranged corresponding to one flow division pipe 9; the retainer ring 14 is arranged at the bottom of the water storage cavity, and the shunt pipe 9 is arranged in the retainer ring 14. The retainer ring 14 is used for preventing the circulating water from influencing the water level of the water distribution plate 8 and the like. Two retaining rings 14 with the height of 15-20mm and the diameter of 30mm are arranged at the geometric center of the water distribution plate 8, the retaining rings 14 are connected with the water distribution plate 8 through welding, the water distribution plate 8 is connected with the inner wall of the sterilization cavity 15 through a support, preferably, the flow dividing pipe 9 is U-shaped, the middle part of the flow dividing pipe 9 is connected to a constant pressure pipe 18 in the cabinet, two retaining rings 14 are arranged on each water distribution plate 8, two ends of the U-shaped flow dividing pipe 9 are respectively arranged in the retaining rings 14, and two end parts of the flow dividing pipe 9 are respectively provided with a flow adjusting flower disc 13.
The flux of a flow dividing pipe 9 can be adjusted by the relative rotation of the two flow adjusting faceplates 13, the water outlet of the flow dividing pipe 9 extends into the retainer ring 14 by 5mm, and the upper end of the flow dividing pipe 9 is connected with a constant pressure pipe 18 in the cabinet; the shunt tubes 9 are uniformly distributed on the constant-pressure tubes 18 in the cabinet, and the diameter of the constant-pressure tubes 18 in the cabinet is more than 2 times of that of the shunt tubes 9; the upper end of the constant-pressure pipe 18 in the cabinet is connected with the constant-pressure pipe 5 outside the cabinet through the sterilization cavity 15, the diameter of the constant-pressure pipe 5 outside the cabinet is about 2 times of the diameter of the constant-pressure pipe 18 in the cabinet, and the length of the constant-pressure pipe is equivalent to that of the constant-pressure pipe 18 in the cabinet; the joint of the constant pressure pipe 18 in the cabinet and the constant pressure pipe 5 outside the cabinet is the geometric center of the constant pressure pipe 5 outside the cabinet.
As shown in fig. 7, in the present embodiment, the sterilization rack 16 includes: the sterilization box 22 of a plurality of range upon range of settings, be equipped with in the sterilization box 22 and place the chamber, the bottom of sterilization box 22 is for having cavity intermediate layer 25, a plurality of second that run through holes 23 that leak are seted up to the roof of cavity intermediate layer 25, a plurality of third that run through holes 24 that leak are seted up to the diapire of cavity intermediate layer 25, the aperture that the second leaked holes 23 is greater than the aperture that the third leaked holes 24. The height of the hollow interlayer 25 is about 8-12mm, the diameter of the third water leakage hole 24 is about 2mm, and the diameter of the second water leakage hole 23 is about 6-8 mm.
As shown in fig. 4 to 6, in the present embodiment, the circulating water constant pressure system includes: the inlet of the balance pipe 4 is communicated with the water outlet of the temperature equalizing device; the water inlet of the constant pressure tank 3 is communicated with the outlet of the balance pipe 4; the constant voltage tube 5 outside the cabinet, the delivery port of constant voltage jar 3 is connected with the constant voltage tube 5 outside the cabinet, the constant voltage tube 5 outside the cabinet is connected with the constant voltage tube 18 in the cabinet through the connecting pipe, the connecting pipe is sealed to set firmly on the lateral wall of sterilizer 1. The diameter of the pipeline of the connecting pipe is equivalent to the diameter of the constant pressure pipe 5 outside the cabinet. The balance pipe 4 and the constant pressure tank 3 are respectively provided with two parts which are respectively and symmetrically arranged at two sides of the temperature equalizing device; the pipe diameter of the balance pipe 4 is arranged from big to small from one end far away from the constant pressure tank 3 to one end close to the constant pressure tank 3.
The diameter of the constant pressure tank 3 is 3-6 times of that of the constant pressure pipe 5 outside the cabinet, and the height of the constant pressure tank is 4-5 times of that of the constant pressure pipe 5 outside the cabinet; the constant pressure tank 3 is provided with a temperature controller 10; the upper end of the constant pressure tank 3 is connected with a balance pipe 4, the balance pipe 4 consists of three sections of pipes with diameters gradually reduced, and the constant pressure tank 3 is connected with the end with the smallest diameter of the balance pipe 4; the three-stage design has the advantages that: gas in the circulating water is collected at the large pipe and then buffered by the medium pipe, the possibility of gas generation of the circulating water flowing into the small pipe is reduced, and meanwhile, according to a fluid flow formula, the flow Q in the pipe is S V; q (flow in the pipe, in cubic meters per second); s (effective cross-sectional area of the pipe, in square meters); v (flow velocity through the medium in the pipe in meters per second); known from the formula, the pipe diameter diminishes gradually, and under the certain condition of total circulating water yield, the circulating line pipe diameter diminishes, and the flow increase of unit cross-sectional area, its benefit lies in: the water pressure is certain (the circulating pump outputs stably), and the flow passing through the small pipe diameter of the balance pipe 4 in a unit time is relatively consistent under the condition that the flow of the water mixing pipe 12 flowing to the balance pipes 4 on the two sides is inconsistent.
In this embodiment, the temperature uniforming device includes: the temperature controllers 10, the temperature controllers 10 are respectively arranged on the constant pressure tanks 3; the temperature balancing device 11 is arranged on the balancing pipe 4; and the water outlet end of the water mixing pipe 12 is respectively communicated with the water inlets of the two balance pipes 4. The heating heat exchange device comprises a heating heat exchanger 2 and a first water pump 6, the water inlet end of the first water pump 6 is communicated with the bottom of the sterilizer 1, the water outlet end of the first water pump 6 is communicated with the water inlet of the heating heat exchanger 2, and the water outlet of the heating heat exchanger 2 is connected with the water inlet end of the water mixing pipe 12. The refrigeration heat exchange device comprises a refrigeration heat exchanger 7 and a second water pump 20, wherein the water inlet end of the second water pump 20 is communicated with the bottom of the sterilizer 1, preferably the lowest point of the bottom of the sterilizer 1, the water outlet end of the second water pump 20 is communicated with the water inlet of the refrigeration heat exchanger 7, and the water outlet of the refrigeration heat exchanger 7 is connected with the water inlet end of the water mixing pipe 12.
The temperature balancing device 11 is wound on the middle section of the balancing pipe 4, and the temperature balancing device 11 is a double-winding cold (heat) exchange device; the maximum pipe diameter end of the balance pipe 4 is connected with the water mixing pipe 12, the diameter of the water mixing pipe 12 is 2 times of the maximum pipe diameter of the balance pipe 4, and the connecting position of the maximum pipe diameter end of the balance pipe 4 and the water mixing pipe 12 is located at 1/2 of the geometric dimension inside the water mixing pipe 12; the other end of the water mixing pipe 12 is connected with a water circulation pipeline in the cabinet through a reducing pipe, and the other end of the water circulation pipeline in the cabinet is connected with a water heat exchanger in the cabinet. The water pipeline in the cabinet is respectively connected with the water inlet ends of the refrigerating heat exchanger 7 and the heating heat exchanger 2, the medium end of the refrigerating heat exchanger 7 is connected with cooling water, the medium end of the heating heat exchanger 2 is connected with steam, and the water outlet ends of the refrigerating heat exchanger 7 and the heating heat exchanger 2 are connected with the water inlet end of the water mixing pipe 12 through pipelines.
When the sterilizer 1 is in the temperature-raising stage: circulating water in the cabinet is pumped out along the arrow direction through the first water pump 6 and the second water pump 20 and respectively enters the refrigerating heat exchanger 7 and the heating heat exchanger 2 along a circulating water pipeline 19 in the cabinet, a steam valve at a medium end of the heating heat exchanger 2 is opened, and the circulating water in the cabinet is heated by steam; the cooling water valve at the medium end of the refrigeration heat exchanger 7 is in a closed state, the refrigeration heat exchanger 7 is used as a bypass of the heating heat exchanger 2 in the temperature rising stage to play a role in balancing water temperature, and deformation caused by imbalance of internal and external pressures of the medicine 17 due to the fact that the pressure of the sterilization cavity 15 rises rapidly and the pressure of the medicine 17 is too high due to rapid temperature rising of circulating water in the cabinet is avoided.
The circulating water in the cabinet flowing through the refrigerating heat exchanger 7 and the heating heat exchanger 2 is mixed in the water mixing pipe 12, so that the water temperature is relatively uniform, the mixed circulating water respectively flows into the balance pipe 4 along the arrow direction and then flows into the constant pressure tank 3, and the pipe diameter of the balance pipe 4 is reduced from large to small, so that the water flow and the pressure flowing into the constant pressure tank 3 are relatively uniform; the temperature controller 10 is installed on the constant pressure tanks 3, the temperature controller 10 detects the temperature difference of the circulating water in the constant pressure tanks 3 and starts steam adding to finely adjust the temperature through a temperature balancing device 11 arranged at the middle section of the balancing pipe 4, so that the temperature of the circulating water in the constant pressure tanks 3 is similar; circulating water with similar temperature and pressure enters the constant pressure pipe 5 outside the cabinet through the constant pressure tank 3, flows into the constant pressure pipe 18 inside the cabinet after secondary constant pressure, flows into the water distribution discs 8 through the flow dividing pipe 9 after tertiary constant pressure, and the slight flow difference of the water distribution discs 8 is realized through the flow adjusting flower disc 13 arranged at the outlet ends of the water distribution pipes.
Circulating water flowing into the water distribution disc 8 is blocked by the retaining ring 14 and then flows into the water storage cavity of the water distribution disc 8 to form a constant water level, so that the circulating water is uniformly distributed in each first water leakage hole 21 of the water distribution disc 8, and the outflow water volume is consistent; the retainer ring 14 is used for preventing the circulating water from influencing the liquid level of the water distribution plate 8 and the like; the heated circulating water showers the medicines 17 stored in the sterilizing box 22 through the first water leakage holes 21 uniformly distributed on the water distribution plate 8, so that each medicine 17 is guaranteed to be showered by the circulating water with the same temperature and flow at the same time; the circulating water flowing through the surface of the first layer of the medicine 17 passes through the second water leakage hole 23 at the upper end of the sterilizing box 22, forms a constant liquid level water surface in the hollow interlayer 25, and then showers the medicine 17 of the next layer through the third water leakage hole 24 at the lower layer of the sterilizing box 22.
The sterilization and heat preservation stage has the same principle as the temperature rise stage;
in the sterilization and cooling stage, a cooling water valve at the medium end of the heating heat exchanger 2 is opened, and circulating water in the cabinet is cooled by cooling water; the steam valve at the medium end of the heating heat exchanger is in a closed state, and the heating heat exchanger 2 is used as a bypass of the refrigerating heat exchanger 7 in the cooling stage to play a role in balancing water temperature, so that deformation caused by unbalanced internal and external pressures of the medicine 17 due to rapid cooling of circulating water in the cabinet is avoided; meanwhile, the temperature controller 10 detects the temperature difference of the circulating water in the constant-pressure tanks 3 and starts cooling water to finely adjust the temperature through the temperature balancing device 11 arranged at the middle section of the balancing pipe 4, so that the temperature of the circulating water in the constant-pressure tanks 3 is close, the temperature balancing device 11 stops working when the temperature is lower than 100 ℃, and other working flows are the same as the temperature rise stage.
FIG. 8 is a test chart of the temperature uniformity of the sterilizer 1 using wireless verifiers, which are distributed in one unit per cube; it can be seen from the figure that the temperature difference at the same time point is only 0.16 ℃ after the system of the present invention is adopted, which is much less than the level of 1.5 ℃ in the industry and the level of +/-1 ℃ required by the regulations, and the overall temperature uniformity is 0.12 ℃.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.
Claims (10)
1. The utility model provides a water bath sterilization temperature pressure water distribution system that homogenizes which characterized in that includes:
the sterilizer comprises a sterilizer (1), wherein a sterilization cavity (15) is arranged in the sterilizer (1);
the sterilization rack (16), the sterilization rack (16) is arranged in the sterilization cavity (15) in a sliding manner;
the water distribution system is arranged above the sterilization cavity (15) and is used for performing spray sterilization on the products on the sterilization rack (16);
the circulating water constant pressure system is arranged above the sterilizer (1) and is connected with the water distribution system;
the temperature equalizing device is arranged on the circulating water constant pressure system.
2. The system of claim 1, further comprising: a heating heat exchange device and a refrigerating heat exchange device which are respectively communicated with the temperature equalizing device.
3. The water bath sterilization temperature and pressure uniform water distribution system according to claim 2, characterized in that the water distribution system comprises:
the constant-pressure pipe (18) in the cabinet is communicated with the water outlet end of the circulating water constant-pressure system;
the shunt tubes (9), a plurality of shunt tubes (9) are connected to a constant pressure tube (18) in the cabinet at equal intervals;
water distribution plate (8): the water distribution disks (8) are arranged at the top of the sterilization cavity (15), a water storage cavity is arranged in each water distribution disk (8), a plurality of first water leakage holes (21) are arranged at the bottom of the water storage cavity, and each water distribution disk (8) is arranged corresponding to one flow division pipe (9);
the check ring (14), the check ring (14) sets up the bottom in depositing the water chamber, shunt tubes (9) set up in check ring (14).
4. A water bath sterilization temperature and pressure uniform water distribution system as claimed in claim 3, wherein the dividing pipe (9) is U-shaped, the middle part of the dividing pipe (9) is connected to a constant pressure pipe (18) in the cabinet, two retaining rings (14) are arranged on each water distribution plate (8), two ends of the U-shaped dividing pipe (9) are respectively arranged in the retaining rings (14), and two end parts of the dividing pipe (9) are respectively provided with a flow regulating flower disc (13).
5. The temperature and pressure uniform water distribution system for water bath sterilization according to claim 3, wherein the circulating water constant pressure system comprises:
the inlet of the balance pipe (4) is communicated with the water outlet of the temperature homogenizing device;
the water inlet of the constant pressure tank (3) is communicated with the outlet of the balance pipe (4);
the outer constant voltage pipe of cabinet (5), the delivery port and the outer constant voltage pipe of cabinet (5) of constant voltage jar (3) are connected, the outer constant voltage pipe of cabinet (5) are connected with interior constant voltage pipe of cabinet (18) through the connecting pipe, the connecting pipe is sealed to set firmly on the lateral wall of sterilizer (1).
6. The temperature and pressure uniform water distribution system for water bath sterilization according to claim 5, wherein the balance pipe (4) and the constant pressure tank (3) are provided in two parts and are symmetrically arranged on two sides of the temperature uniform device respectively; the pipe diameter of the balance pipe (4) is arranged from one end far away from the constant pressure tank (3) to one end close to the constant pressure tank (3) from large to small.
7. The temperature and pressure uniform water distribution system for water bath sterilization according to claim 6, wherein the temperature uniform device comprises:
the temperature controllers (10), the temperature controllers (10) are respectively arranged on the constant pressure tank (3);
a temperature balancing device (11), the temperature balancing device (11) being arranged on the balancing pipe (4);
and the water outlet end of the water mixing pipe (12) is respectively communicated with the water inlets of the two balance pipes (4).
8. The water bath sterilization temperature and pressure uniform water distribution system as claimed in claim 7, wherein the heating and heat exchange device comprises a heating heat exchanger (2) and a first water pump (6), the water inlet end of the first water pump (6) is communicated with the bottom of the sterilizer (1), the water outlet end of the first water pump (6) is communicated with the water inlet of the heating heat exchanger (2), and the water outlet of the heating heat exchanger (2) is connected with the water inlet end of the water mixing pipe (12).
9. The water bath sterilization temperature and pressure uniform water distribution system as claimed in claim 7, wherein the refrigeration heat exchange device comprises a refrigeration heat exchanger (7) and a second water pump (20), the water inlet end of the second water pump (20) is communicated with the bottom of the sterilizer (1), the water outlet end of the second water pump (20) is communicated with the water inlet of the refrigeration heat exchanger (7), and the water outlet of the refrigeration heat exchanger (7) is connected with the water inlet end of the water mixing pipe (12).
10. The temperature and pressure uniform water distribution system for water bath sterilization according to claim 1, wherein the sterilization rack (16) comprises: the sterilization box (22) of a plurality of range upon range of settings, be equipped with in sterilization box (22) and place the chamber, the bottom of sterilization box (22) is for having cavity intermediate layer (25), a plurality of second that run through hole (23) that leak are seted up to the roof of cavity intermediate layer (25), a plurality of third that run through hole (24) that leak are seted up to the diapire of cavity intermediate layer (25), the aperture that the second leaked hole (23) is greater than the aperture that the third leaked hole (24).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011372941.XA CN112402634A (en) | 2020-11-30 | 2020-11-30 | Water bath sterilization temperature pressure water distribution system that evenly distributes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011372941.XA CN112402634A (en) | 2020-11-30 | 2020-11-30 | Water bath sterilization temperature pressure water distribution system that evenly distributes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112402634A true CN112402634A (en) | 2021-02-26 |
Family
ID=74828851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011372941.XA Pending CN112402634A (en) | 2020-11-30 | 2020-11-30 | Water bath sterilization temperature pressure water distribution system that evenly distributes |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112402634A (en) |
-
2020
- 2020-11-30 CN CN202011372941.XA patent/CN112402634A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN207285080U (en) | A kind of sterilization machine for producing vegetable protein beverage | |
| CN214511947U (en) | Water bath sterilization temperature pressure water distribution system that evenly distributes | |
| CN106399084A (en) | Probiotic culture system | |
| CN112402634A (en) | Water bath sterilization temperature pressure water distribution system that evenly distributes | |
| CN202892568U (en) | Heating device for infusion appliance | |
| CN208838630U (en) | A kind of Multifunctional sterilization device of Novel bunk temperature steam ozone combination | |
| CN201036621Y (en) | Sterilizing baking oven | |
| CN112402635A (en) | Water bath sterilization equipment capable of remarkably improving medicine sterilization effect | |
| US10821219B2 (en) | Cold and heat exchange system for cardiac surgical operation with cardiac arrest | |
| CN103394150B (en) | Thermostatic controller for medical fluid | |
| CN214710075U (en) | Fluid high-temperature sterilization equipment | |
| CN218628437U (en) | Water-bath sterilization water distribution temperature and flow detection equipment for large infusion product | |
| CN105384290A (en) | Method and an apparatus for continuously sterilizing water for spraying the pistons in a piston pump or a homogenizer | |
| CN204742518U (en) | Food sterilization apparatus | |
| CN115773785A (en) | Water distribution temperature and flow detection method for large infusion product water bath sterilization equipment | |
| CN207369997U (en) | A kind of energy-efficient board-like sterilization machine | |
| CN208809118U (en) | A kind of sterilized device of drug | |
| CN115790717A (en) | Water bath sterilization water distribution temperature and flow detection equipment for large infusion product | |
| CN219071416U (en) | Water bath sterilization water consumption collecting and temperature measuring device for large infusion product | |
| CN206037581U (en) | A cold and hot exchange water tank for cardiac surgery stops jump and performs operation | |
| CN111728026A (en) | Ultrasonic double-set coil pipe milk sterilization system | |
| CN219251040U (en) | Accurate adjustable large infusion sterilization water distribution temperature and flow detection system | |
| CN201030065Y (en) | Water-bath type sterilizing device | |
| CN205653149U (en) | Thermal -insulated system of cooling of filling elemene liquid medicine | |
| CN207767449U (en) | A kind of board-like sterilization machine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |