CN112402490A - Antibacterial, soothing and desquamation-preventing hand cream and preparation method thereof - Google Patents
Antibacterial, soothing and desquamation-preventing hand cream and preparation method thereof Download PDFInfo
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- CN112402490A CN112402490A CN202011282336.3A CN202011282336A CN112402490A CN 112402490 A CN112402490 A CN 112402490A CN 202011282336 A CN202011282336 A CN 202011282336A CN 112402490 A CN112402490 A CN 112402490A
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- extract
- ascorbic acid
- hand cream
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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Abstract
The invention discloses an antibacterial, relieving and desquamation-preventing hand cream which mainly comprises a purslane extract, a fig leaf extract, sodium chloride, ascorbic acid and glycerol. The invention also provides a preparation method of the antibacterial, soothing and desquamation-preventing hand cream, which comprises the following steps: 1) preparing herba Portulacae extract, folium fici extract, ascorbic acid solution, and normal saline; 2) respectively injecting ascorbic acid solution, herba Portulacae extract, and folium fici extract into physiological saline, stirring, adding glycerol, stirring, microwave heating, and stirring. The hand cream adopts natural plant extract as raw material, is not easy to cause irritation to skin, and has high-efficiency antibacterial effect to avoid bacterial dermatitis. The combination of glycerol and ascorbic acid can moisten skin and prevent skin cells from cracking and falling off due to water loss. In addition, the process for preparing the hand cream is simple and easy to understand, and is suitable for large-scale popularization and propagation.
Description
Technical Field
The invention relates to the technical field of medical preparations, in particular to an antibacterial, relieving and desquamation-preventing hand cream and a method for preparing the hand cream.
Background
Dermatitis (dermatitis) is a generic term for inflammatory skin diseases caused by various internal and external infections or non-infectious factors, is not an independent disease, and has complex and various etiology and clinical manifestations, repeated onset and difficult clinical treatment. External factors causing dermatitis may be induced or aggravated by inhalants (e.g., pollen, dust mites, etc.), living environments (e.g., cold, hot, dry, etc.), animal fur, various physicochemical substances (e.g., cosmetics, soaps, synthetic fibers, etc.).
The external medicament for treating dermatitis has a plurality of varieties, most of the external medicaments are hormones, such as naloxone, ewing, dermatitis and the like, and the external medicaments have obvious anti-inflammatory and anti-allergic effects in short-term application, but easily cause hormone secretion disorder and other problems in long-term application. Moreover, the hormone medicines only play a role in treatment and cannot provide a protective function.
Disclosure of Invention
The invention discloses an antibacterial, soothing and desquamation-preventing hand cream, which is used for solving one or more technical problems in the prior art and at least providing a beneficial choice or creation condition.
An antibacterial hand cream for relieving and preventing desquamation is mainly prepared from herba Portulacae extract, folium fici extract, sodium chloride, ascorbic acid and glycerol. Preferably, the hand cream comprises, by mass, 10-20% of purslane extract, 15-25% of fig extract, 0.1-0.2% of ascorbic acid, 0.05-0.10% of glycerol and the balance of normal saline.
Purslane (also known as purslane, changlium, etc.) Portulaca oleracea L.is an annual herbaceous plant of Portulacaceae, is distributed in various regions in China, is a plant used as both medicine and food, wherein the medicinal value of purslane has the effects of diminishing inflammation, inhibiting bacteria, enhancing sugar metabolism, enhancing immunity, etc., and is called as natural antibiotic by the medical community.
Ficus carica Linn of Ficus of Moraceae is a woody plant of Ficus of Moraceae, and has wide application in the aspects of raw pharmacy, phytochemistry and traditional pharmacology, and the description of the medicinal value of Ficus carica appears in the book of Lijiliu bark. The traditional Chinese medicine is mainly used for treating leucoderma and skin tinea. Researches prove that the fig leaf extract has a relatively remarkable bacteriostatic action, wherein petroleum ether, chloroform and ethanol extracts of the fig leaves have relatively strong anti-inflammatory action.
Ascorbic acid is also known as vitamin C (C)6H8O6) Is an indispensable substance for maintaining human health, participates in the synthesis of collagen, and promotes the healing of human wounds. Besides, ascorbic acid can also improve the body's ability to meet an emergency: abnormal stimulation of the body, such as severe pain, cold, hypoxia, can cause stress against the abnormal stimulation.
Glycerol (C)3H8O3) Also known as glycerol, is miscible with water and ethanol. Glycerin is a 'guard' of the skin, and contains glycerin in many skin care products, and pure glycerin is not generally used in the skin care products, because the pure glycerin has strong water absorption, and the glycerin has no skin moistening effect when directly used, but can take away moisture on the skin, so that the skin becomes extremely dry or cracked.
The invention also provides a preparation method of the antibacterial, soothing and desquamation-preventing hand cream, which comprises the following steps:
1) preparing herba Portulacae extract, folium fici extract, ascorbic acid solution, and normal saline;
2) respectively injecting ascorbic acid solution, herba Portulacae extract, and folium fici extract into physiological saline, stirring, adding glycerol, stirring, microwave heating, and stirring.
Specifically, the preparation method of the purslane extract comprises the following steps: cleaning fresh purslane, adding ethanol, grinding, wherein the reference ratio of the mass of the purslane to the ethanol is 50:1, filtering juice obtained by grinding through filter paper to obtain a purslane extract, and storing at-4 ℃ for later use.
Specifically, the preparation method of the fig leaf extract comprises the following steps: cleaning fresh fig leaves, adding ethanol, grinding, wherein the mass ratio of the fig leaves to the ethanol is 50:1, filtering the juice obtained by grinding through filter paper to obtain the fig leaf extract, and storing at-4 ℃ for later use.
Furthermore, the power of the microwave heating treatment is 150-200W.
Further, the microwave heating treatment time is 1-2 min.
Compared with the prior art, the hand cream provided by the invention adopts natural plant extracts as raw materials, is not easy to cause irritation to skin, and simultaneously has a high-efficiency antibacterial effect, so that bacterial dermatitis is avoided. The combination of glycerol and ascorbic acid can moisten skin and prevent skin cells from cracking and falling off due to water loss. In addition, the process for preparing the hand cream is simple and easy to understand, and is suitable for large-scale popularization and propagation.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail below.
Example 1, preparation of purslane extract.
The method comprises the following steps: adding 1ml of ethanol into a grinding bottle sterilized at high temperature, adding 50g of fresh purslane, quickly grinding into juice, filtering into a 50ml beaker through a funnel and filter paper to obtain about 15ml of purslane extract, sealing and storing in a refrigerator at-4 ℃ for temporary storage.
Example 2, preparation of fig leaf extract.
The method comprises the following steps: adding 1ml of ethanol into a grinding bottle sterilized at high temperature, adding 50g of fresh fig leaves weighed, quickly grinding into juice, filtering into a 50ml beaker through a funnel and filter paper to obtain about 20ml of fig leaf extract, sealing and storing in a refrigerator at-4 ℃ for temporary storage.
Example 3, preparation of ascorbic acid solution.
The method comprises the following steps: weighing 1g ascorbic acid, adding into 10ml deionized water (the container bottle is wrapped with tinfoil paper to prevent decomposition), preparing 10% ascorbic acid solution, sealing, and storing in refrigerator at-4 deg.C.
Example 4 preparation of an antibacterial, soothing, anti-desquamating hand cream.
The method comprises the following steps:
a) taking a 100ml beaker, and adding 20ml of deionized water into the beaker;
b) 0.9g of sodium chloride is weighed and added into the solution to be stirred continuously until the sodium chloride is dissolved completely;
c) 2ml of the prepared 10% ascorbic acid solution is absorbed by a pipette;
d) absorbing 15ml of purslane extract, absorbing 20ml of fig extract, adding into a beaker, and stirring continuously until the purslane extract and the fig extract are completely mixed together;
e: adding deionized water to a constant volume of 100 ml;
f: weighing 0.09g of glycerol, adding the glycerol into a beaker with a constant volume, stirring, then putting the beaker into a microwave oven for heating for 1min at 150W, and taking out the beaker to stir continuously until the glycerol and the microwave are mixed together completely.
Claims (7)
1. An antibacterial, soothing and desquamation-preventing hand cream is characterized by mainly comprising a purslane extract, a fig leaf extract, sodium chloride, ascorbic acid and glycerol.
2. The bacterium-relieving and anti-desquamation hand cream as claimed in claim 1, which comprises 10-20% of purslane extract, 15-25% of fig extract, 0.1-0.2% of ascorbic acid, 0.05-0.10% of glycerol and the balance of normal saline by mass percent.
3. A preparation method of an antibacterial, relieving and desquamation-preventing hand cream is characterized by comprising the following steps:
1) preparing herba Portulacae extract, folium fici extract, ascorbic acid solution, and normal saline;
2) respectively injecting ascorbic acid solution, herba Portulacae extract, and folium fici extract into physiological saline, stirring, adding glycerol, stirring, microwave heating, and stirring.
4. The method of claim 3, wherein the step of preparing the purslane extract comprises: cleaning fresh purslane, adding ethanol, grinding, wherein the reference ratio of the mass of the purslane to the ethanol is 50:1, filtering juice obtained by grinding through filter paper to obtain a purslane extract, and storing at-4 ℃ for later use.
5. The method for preparing a fig. 3 extract, wherein the method for preparing a fig leaf extract comprises the steps of: cleaning fresh fig leaves, adding ethanol, grinding, wherein the mass ratio of the fig leaves to the ethanol is 50:1, filtering the juice obtained by grinding through filter paper to obtain the fig leaf extract, and storing at-4 ℃ for later use.
6. The method according to claim 3, wherein the power of the microwave heating treatment is 150 to 200W.
7. The method according to claim 3 or 6, wherein the microwave heating treatment is carried out for 1 to 2 min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011282336.3A CN112402490A (en) | 2020-11-17 | 2020-11-17 | Antibacterial, soothing and desquamation-preventing hand cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011282336.3A CN112402490A (en) | 2020-11-17 | 2020-11-17 | Antibacterial, soothing and desquamation-preventing hand cream and preparation method thereof |
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| Publication Number | Publication Date |
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| CN112402490A true CN112402490A (en) | 2021-02-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011282336.3A Pending CN112402490A (en) | 2020-11-17 | 2020-11-17 | Antibacterial, soothing and desquamation-preventing hand cream and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670858A (en) * | 2011-11-02 | 2012-09-19 | 范军伟 | Lotion for treating inflammatory external hemorrhoids |
| CN103610631A (en) * | 2013-12-13 | 2014-03-05 | 王爱丽 | Preparation method of hand cream |
| CN105878121A (en) * | 2016-05-27 | 2016-08-24 | 徐州猎奇商贸有限公司 | Facial cream and preparing method thereof |
| CN109568235A (en) * | 2019-01-28 | 2019-04-05 | 江苏亦加禾健康产业有限公司 | A kind of wet tissue and its manufacturing method with caring function |
-
2020
- 2020-11-17 CN CN202011282336.3A patent/CN112402490A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670858A (en) * | 2011-11-02 | 2012-09-19 | 范军伟 | Lotion for treating inflammatory external hemorrhoids |
| CN103610631A (en) * | 2013-12-13 | 2014-03-05 | 王爱丽 | Preparation method of hand cream |
| CN105878121A (en) * | 2016-05-27 | 2016-08-24 | 徐州猎奇商贸有限公司 | Facial cream and preparing method thereof |
| CN109568235A (en) * | 2019-01-28 | 2019-04-05 | 江苏亦加禾健康产业有限公司 | A kind of wet tissue and its manufacturing method with caring function |
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