CN112401072A - Feed additive for rapidly improving immunity of swinery - Google Patents
Feed additive for rapidly improving immunity of swinery Download PDFInfo
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- CN112401072A CN112401072A CN202011119624.7A CN202011119624A CN112401072A CN 112401072 A CN112401072 A CN 112401072A CN 202011119624 A CN202011119624 A CN 202011119624A CN 112401072 A CN112401072 A CN 112401072A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/168—Steroids
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Abstract
The invention discloses a feed additive for rapidly improving immunity of swinery, and relates to the technical field of animal health products. The invention relates to a feed additive for rapidly improving immunity of swinery, which comprises the following raw materials in parts by weight: 5-8 parts of mannatide, 10-15 parts of phytosterol, 9-12 parts of interleukin, 5-10 parts of prebiotics and 4-8 parts of Chinese medicinal powder additive. The invention discloses a feed additive for rapidly improving the immunity of a swinery, which is reasonable in formula, does not contain hormone components, and can effectively improve the immunity of the swinery.
Description
Technical Field
The invention relates to the technical field of animal health products, in particular to a feed additive for rapidly improving immunity of swinery.
Background
In recent years, diseases of live pigs frequently occur, and at present, the immunity of the live pigs is generally improved by adopting an immunization and vaccination means in a pig farm. However, when the old disease is not going to be new and is imminent, one pig needs to be vaccinated several or even more times for a short lifetime. Not only adds extra burden to the production link, but also adds more production cost. In addition, respiratory tract infection, digestive tract infection, reproductive tract infection and mammary gland infection caused by a plurality of conditional pathogens and stress-responsive diseases caused by unconditional pathogen factors are irregular, so that the requirement for the development of the pig breeding industry cannot be met by only improving the specific immunity of the live pigs through immunization and vaccination. Accordingly, the urgency of improving the nonspecific immunity of the live pigs on preventing and controlling the pig diseases is more and more prominent.
The feed additive is prepared by adding a small amount of or trace amount of nutritive or non-nutritive substances into feed for improving the utilization rate of the feed, ensuring or improving the quality of the feed, meeting the nutritional requirements of the fed animals, promoting the growth of the animals and ensuring the health of the fed animals. Wherein, the feed additive can be divided into medicinal additive and mineral additive. In the last 80-90 years, in order to improve the cultivation level and benefit, various countries in the world use exogenous hormones or mental drug additives in feed and drinking water in sequence, but the harmfulness of residues of the drug additives to the human body through a food chain is also highlighted. In recent years, with the development of breeding industry, a plurality of feed additives come out one after another, so that the breeding level and benefit are improved, but some of the feed additives adopt certain hormones to generate certain influence on human bodies; some of the drugs have unreasonable formula and unsatisfactory effect, and are not suitable for popularization and application.
Disclosure of Invention
Aiming at the problems, the invention aims to disclose a feed additive for rapidly improving the immunity of a swinery, which is reasonable in formula, does not contain hormone components and can effectively improve the immunity of the swinery.
Specifically, the feed additive for rapidly improving the immunity of the swinery comprises the following raw materials in parts by weight: 5-8 parts of mannatide, 10-15 parts of phytosterol, 9-12 parts of interleukin, 5-10 parts of prebiotics and 4-8 parts of Chinese medicinal powder additive.
The feed additive of the invention has the advantages that the mannan peptide can promote peripheral leukocytes of pigs, enhance phagocytic function of reticuloendothelial system, activate macrophages and lymphocytes, induce thymic lymphocytes to generate active substances, and improve and enhance the immune function and stress capability of organisms; the phytosterol has strong anti-inflammatory effect, can promote wound healing, promote muscle proliferation, enhance capillary circulation, promote animal growth and promote animal health; the interleukin plays an important role in transmitting information, activating and regulating immune cells, mediating T, B cell activation, proliferation and differentiation and in inflammatory reaction, and can obviously improve the immunity of animals; the probiotics and the Chinese medicinal powder additive have synergistic effect, can promote the growth and development of animals to improve the disease resistance, stimulate the immune system, strengthen the specific cellular immune response, and achieve the effects of preventing diseases, promoting the growth of the animals and improving the utilization rate of feed by adjusting the microecological balance of the gastrointestinal tracts of the animals.
Further, the feed additive comprises the following raw materials in parts by weight: 6 parts of mannatide, 12 parts of phytosterol, 10 parts of interleukin, 8 parts of prebiotics and 6 parts of Chinese medicinal powder additive.
Further, the traditional Chinese medicine powder additive comprises the following raw materials in parts by weight: 6-12 parts of astragalus, 1-4 parts of angelica, 8-10 parts of prepared rhizome of rehmannia, 4-6 parts of glossy privet fruit, 3-5 parts of schisandra, 5-8 parts of radix ophiopogonis, 1-6 parts of Chinese pulsatilla root, 2-10 parts of madder and 10-12 parts of mulberry leaf.
The Chinese medicinal powder additive contains alkaloid, polysaccharide, saponin, volatile oil, flavone, etc., and can promote the growth of pig immunocyte and the synthesis of antibody, regulate immunity, and enhance immunity.
Further, the traditional Chinese medicine powder additive comprises the following raw materials in parts by weight: 9 parts of astragalus, 2 parts of angelica, 8 parts of prepared rhizome of rehmannia, 5 parts of glossy privet fruit, 3 parts of schisandra fruit, 6 parts of dwarf lilyturf tuber, 4 parts of Chinese pulsatilla root, 10 parts of madder root and 12 parts of mulberry leaf.
Further, the Chinese medicinal powder additive is prepared by fermenting folium mori, performing superfine grinding, and mixing with mixed extracts of the rest components.
The mulberry leaves contain abundant proteins, minerals, amino acids and the like, the mulberry leaves are used as feed additives and can improve the immunocompetence of pigs, the meat quality of the pigs is improved, but the mulberry leaves contain a large amount of lignin and crude fibers, if the lignin and the crude fibers are directly added, the palatability is not good, the feed intake of the pigs to a certain extent is reduced, the mulberry leaves contain a large amount of tannin substances, if the tannin substances are excessively used, the diarrhea is caused, the growth of the pigs is influenced, and because the content of effective components in the traditional Chinese medicines is low, if a good effect is to be achieved, more traditional Chinese medicines are required to be added, the taste of the feed is influenced, and the feed intake of the pigs is further influenced.
According to the invention, after the mulberry leaves are fermented, the mouthfeel of the mulberry leaves can be improved, the tannin content in the mulberry leaves can be reduced, the feed intake of pigs can be increased, and the fermentation treatment can also increase the conversion rate of plant protein in the mulberry leaves, so that the absorption rate of the pigs can be increased.
Further, the fermentation pretreatment of the mulberry leaves comprises the following specific steps: cleaning, stalk removing and drying mulberry leaves collected after frost, then cutting, adding oxalic acid solution with the mass fraction of 2-4%, soaking for 2-4h, taking out, cleaning, drying and uniformly mixing with rapeseed cake to obtain a mixed material, adding cellulase with the mass fraction of 1-1.5% of the mixed material into the mixed material, stirring and uniformly mixing, heating to 50-60 ℃, keeping the temperature for 12-24h, adding complex enzyme for uniformly mixing, adding oxalic acid solution to adjust the pH value to 5-6, adding deionized water, stirring and uniformly mixing, fermenting for 4-7d at the temperature of 30-45 ℃, taking out and drying after fermentation to obtain the fermented mulberry leaves.
Soaking the mulberry leaves with oxalic acid solution in the process of fermentation, not only inactivating the infectious microbes and harmful microorganisms existing on the mulberry leaves, but also destroying the crystallinity and the degree of polymerization of cellulose in the mulberry leaves to a certain extent, being more beneficial to subsequent fermentation treatment, removing tannin in partial mulberry leaves to a certain extent through the soaking treatment of the oxalic acid solution, and further improving the palatability of the fermented mulberry leaves.
Further, the compound enzyme comprises 2.4 multiplied by 109CFU/g Bacillus subtilis, 2.2X 108CFU/g Saccharomyces cerevisiae, 2.5 × 108CFU/g Lactobacillus plantarum, 2.8X 109CFU/g Aspergillus oryzae.
Further, the preparation method of the traditional Chinese medicine powder additive specifically comprises the following steps:
s1: taking radix astragali, radix Angelicae sinensis, radix rehmanniae Preparata, fructus Ligustri Lucidi, fructus Schisandrae chinensis, radix Ophiopogonis, radix Pulsatillae and radix Rubiae according to the mass ratio, drying, parching with slow fire until fragrance overflows, taking out, naturally airing to normal temperature, adding into a bulking machine, performing high-pressure bulking treatment under the conditions of the temperature of 95-100 ℃ and the pressure of 6-8MPa, cooling to room temperature after the treatment is completed, taking out, grinding into powder to obtain mixed powder, adding ethanol solution with the mass of 6-8 times of the mixed powder into the mixed powder, soaking for 2-3h, performing ultrasonic extraction for 30-40min, filtering to obtain ultrasonic extract and ultrasonic extraction residue, performing low-temperature plasma treatment on the ultrasonic extraction residue, adding deionized water with the mass of 4-6 times of the ultrasonic extraction residue into a high-pressure kettle, decocting for 20-30min under high pressure, filtering to obtain high-pressure extract and high, mixing the ultrasonic extracting solution and the high-pressure extracting solution, concentrating under reduced pressure to obtain extract, and drying to obtain a mixed extract;
s2: drying fermented folium Mori in 60 deg.C drying oven for 2-3h, pulverizing in common pulverizer, sieving with 100 mesh sieve, pulverizing in ultramicro pulverizer, sieving with 300 mesh sieve, adding mixed extract, stirring, and mixing to obtain Chinese medicinal powder additive.
During the process of extracting the traditional Chinese medicine powder, firstly, cellulose, lignin and the like in cell walls of the traditional Chinese medicine are destroyed through puffing treatment to be loosened, so that the subsequent ultrasonic extraction is facilitated, after the ultrasonic extraction, low-temperature plasma treatment is carried out on ultrasonic extraction residues, generated plasmas bombard the surfaces of the traditional Chinese medicine powder to further destroy the cell walls, and then, the subsequent high-pressure decoction is combined, so that effective components of the traditional Chinese medicine can be extracted as far as possible.
Further, the particle size of the traditional Chinese medicine powder additive is 12-15 μm.
The invention has the beneficial effects that:
1. the invention discloses a feed additive for rapidly improving the immunity of a swinery, which is reasonable in formula, does not contain hormone components, and can effectively improve the immunity of the swinery.
2. The traditional Chinese medicine powder additive is prepared by mixing fermented mulberry leaves and the mixed extract of traditional Chinese medicines, is beneficial to absorption of pigs, can achieve corresponding effect by adding a small amount of the traditional Chinese medicine powder additive, can reduce the influence on the mouthfeel of feed to a certain extent, and improves the feed intake of pigs.
Detailed Description
The present invention will be described in detail with reference to specific examples below:
example one
Fermentation pretreatment of mulberry leaves
Cleaning folium Mori collected after frost, removing stalk, oven drying, adding oxalic acid solution with mass fraction of 2%, soaking for 3h, taking out, cleaning, oven drying, mixing with rapeseed cake to obtain a mixture, wherein the mass ratio of folium Mori to rapeseed cake is 3:1, adding cellulase with mass fraction of 1.5% into the mixture, stirring, mixing, heating to 55 deg.C, keeping the temperature for 18h, adding complex enzyme at mass ratio of 46:0.5, and mixing well, wherein the complex enzyme comprises 1.2 × 109CFU/g Bacillus licheniformis、2.2×108CFU/g Saccharomyces cerevisiae, 1.2 × 108CFU/g Lactobacillus plantarum, 1.6X 109Adding oxalic acid solution into the CFU/g lactobacillus to adjust the pH value to 5-6, adding deionized water, stirring and mixing uniformly, fermenting for 6d at the temperature of 45 ℃, taking out after fermentation is finished, and drying to obtain the fermented mulberry leaves.
Preparation of Chinese medicinal powder additive
S1: taking 9 parts of astragalus, 2 parts of angelica, 8 parts of prepared rhizome of rehmannia, 5 parts of glossy privet fruit, 3 parts of Chinese magnoliavine fruit, 6 parts of dwarf lilyturf tuber, 4 parts of Chinese pulsatilla root and 10 parts of madder root according to the mass ratio, drying the dried materials by slow fire until fragrance overflows, taking the materials out, naturally airing the materials to the normal temperature, adding the materials into a bulking machine, carrying out high-pressure bulking treatment at the temperature of 100 ℃ and under the pressure of 6MPa, cooling the materials to the room temperature after the treatment is finished, taking the materials out, grinding the materials into powder to obtain mixed powder, adding an ethanol solution with the mass of 8 times of the mixed powder into the mixed powder, soaking the mixed powder for 3 hours, carrying out ultrasonic extraction for 35 minutes, filtering to obtain an ultrasonic extracting solution and ultrasonic extraction residues, carrying out low-temperature plasma treatment on the ultrasonic extraction residues for 6 minutes by taking argon as working gas at the power of 600W and at the temperature of 45 ℃, adding deionized, mixing the ultrasonic extracting solution and the high-pressure extracting solution, concentrating under reduced pressure to obtain extract, and drying to obtain a mixed extract;
s2: drying 9 parts of fermented mulberry leaves in a drying box at 60 ℃ for 3 hours, placing the dried mulberry leaves in a common pulverizer to pulverize, sieving with a 100-mesh sieve, then adding the crushed mulberry leaves into a superfine pulverizer to pulverize, sieving with a 300-mesh sieve, then adding the mixed extract, and stirring and mixing uniformly to obtain the traditional Chinese medicine powder additive.
Preparation of feed additive
Respectively weighing 6 parts of mannatide, 12 parts of phytosterol, 10 parts of interleukin, 8 parts of prebiotics and 6 parts of Chinese medicinal powder additive according to the mass ratio, and uniformly stirring and mixing to obtain the feed additive.
Example two
Fermentation pretreatment of mulberry leaves
Cleaning folium Mori collected after frost, removing stem, oven drying, adding the above materialsSoaking 3% oxalic acid solution for 4h, taking out, cleaning, drying, mixing with rapeseed cake to obtain a mixture, wherein the mass ratio of folium Mori to rapeseed cake is 2:1, adding cellulase with the mass ratio of 1.2% to the mixture, stirring, heating to 60 deg.C, keeping the temperature for 12h, adding complex enzyme according to the mass ratio of 90:2, and mixing well, wherein the complex enzyme comprises 1.2 × 109CFU/g Bacillus licheniformis, 2.2X 108CFU/g Saccharomyces cerevisiae, 1.2 × 108CFU/g Lactobacillus plantarum, 1.6X 109Adding oxalic acid solution into the CFU/g lactobacillus to adjust the pH value to 5-6, adding deionized water, stirring and mixing uniformly, fermenting for 4 days at the temperature of 40 ℃, taking out and drying after fermentation is finished to obtain the fermented mulberry leaves.
Preparation of Chinese medicinal powder additive
S1: taking 12 parts of astragalus, 1 part of angelica, 10 parts of prepared rehmannia root, 4 parts of glossy privet fruit, 5 parts of Chinese magnoliavine fruit, 8 parts of dwarf lilyturf tuber, 1 part of Chinese pulsatilla root and 2 parts of madder root according to the mass ratio, drying the materials by slow fire until fragrance overflows, taking the materials out, naturally airing the materials to the normal temperature, adding the materials into a bulking machine, carrying out high-pressure bulking treatment at the temperature of 100 ℃ and the pressure of 7MPa, cooling the materials to the room temperature after the treatment is finished, taking the materials out, grinding the materials into powder to obtain mixed powder, adding an ethanol solution with the mass of 6 times of the mixed powder into the mixed powder, soaking the mixed powder for 2 hours, carrying out ultrasonic extraction for 40 minutes, filtering the obtained ultrasonic extraction liquid and ultrasonic extraction residues, carrying out low-temperature plasma treatment on the ultrasonic extraction residues for 6 minutes by taking argon as working gas at the power of 800W and the temperature of 45 ℃, adding deionized water with the mass of, mixing the ultrasonic extracting solution and the high-pressure extracting solution, concentrating under reduced pressure to obtain extract, and drying to obtain a mixed extract;
s2: drying 10 parts of fermented mulberry leaves in a drying oven at 60 ℃ for 2 hours, placing the dried mulberry leaves in a common pulverizer to pulverize, sieving with a 100-mesh sieve, then adding the crushed mulberry leaves into a superfine pulverizer to pulverize, sieving with a 300-mesh sieve, then adding the mixed extract, and uniformly stirring and mixing to obtain the traditional Chinese medicine powder additive.
Preparation of feed additive
Respectively weighing 8 parts of mannatide, 10 parts of phytosterol, 12 parts of interleukin, 10 parts of prebiotics and 4 parts of Chinese medicinal powder additive according to the mass ratio, and stirring and mixing uniformly to obtain the feed additive.
EXAMPLE III
Fermentation pretreatment of mulberry leaves
Cleaning folium Mori collected after frost, removing stalk, oven drying, adding oxalic acid solution with mass percent of 4%, soaking for 2h, taking out, cleaning, oven drying, mixing with rapeseed cake to obtain a mixture, wherein the mass ratio of folium Mori to rapeseed cake is 1:1, adding cellulase with mass percent of 1% of the mixture into the mixture, stirring, mixing, heating to 50 deg.C, keeping the temperature for 24h, adding complex enzyme according to the mass ratio of 80:1.5, and mixing well, wherein the complex enzyme comprises 1.2 × 109CFU/g Bacillus licheniformis, 2.2X 108CFU/g Saccharomyces cerevisiae, 1.2 × 108CFU/g Lactobacillus plantarum, 1.6X 109Adding oxalic acid solution into the CFU/g lactobacillus to adjust the pH value to 5-6, adding deionized water, stirring and mixing uniformly, fermenting for 7d at the temperature of 30 ℃, taking out after fermentation is finished, and drying to obtain the fermented mulberry leaves.
Preparation of Chinese medicinal powder additive
S1: taking 6 parts of astragalus, 4 parts of angelica, 9 parts of prepared rhizome of rehmannia, 6 parts of glossy privet fruit, 4 parts of Chinese magnoliavine fruit, 5 parts of dwarf lilyturf tuber, 6 parts of Chinese pulsatilla root and 8 parts of madder root according to the mass ratio, drying the materials, frying the materials by slow fire until fragrance overflows, taking the materials out, naturally airing the materials to the normal temperature, adding the materials into a bulking machine, carrying out high-pressure bulking treatment under the conditions that the temperature is 95 ℃ and the pressure is 8MPa, cooling the materials to the room temperature after the treatment is finished, taking the materials out, grinding the materials into powder to obtain mixed powder, adding an ethanol solution with the mass being 7 times of the mixed powder into the mixed powder, soaking the mixed powder for 3 hours, carrying out ultrasonic extraction for 30 minutes, filtering to obtain an ultrasonic extracting solution and ultrasonic extraction residues, carrying out low-temperature plasma treatment on the ultrasonic extraction residues for 6 minutes by taking argon as working gas at the power of 800W and the temperature of, mixing the ultrasonic extracting solution and the high-pressure extracting solution, concentrating under reduced pressure to obtain extract, and drying to obtain a mixed extract;
s2: drying 12 parts of fermented mulberry leaves in a drying oven at 60 ℃ for 3 hours, placing the dried mulberry leaves in a common pulverizer to pulverize, sieving with a 100-mesh sieve, then adding the crushed mulberry leaves into a superfine pulverizer to pulverize, sieving with a 300-mesh sieve, then adding the mixed extract, and stirring and mixing uniformly to obtain the traditional Chinese medicine powder additive.
Preparation of feed additive
Respectively weighing 5 parts of mannatide, 15 parts of phytosterol, 9 parts of interleukin, 5 parts of prebiotics and 8 parts of Chinese medicinal powder additive according to the mass ratio, and stirring and mixing uniformly to obtain the feed additive.
Although the present invention has been described in detail with reference to the preferred embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted without departing from the spirit and scope of the invention as defined in the appended claims. The techniques, shapes, and configurations not described in detail in the present invention are all known techniques.
Claims (9)
1. The feed additive for rapidly improving the immunity of swinery is characterized by comprising the following raw materials in parts by weight: 5-8 parts of mannatide, 10-15 parts of phytosterol, 9-12 parts of interleukin, 5-10 parts of prebiotics and 4-8 parts of Chinese medicinal powder additive.
2. The feed additive for rapidly improving the immunity of a swinery according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 6 parts of mannatide, 12 parts of phytosterol, 10 parts of interleukin, 8 parts of prebiotics and 6 parts of Chinese medicinal powder additive.
3. The feed additive for rapidly improving the immunity of a swinery according to claim 2, wherein the traditional Chinese medicine powder additive comprises the following raw materials in parts by weight: 6-12 parts of astragalus, 1-4 parts of angelica, 8-10 parts of prepared rhizome of rehmannia, 4-6 parts of glossy privet fruit, 3-5 parts of schisandra, 5-8 parts of radix ophiopogonis, 1-6 parts of Chinese pulsatilla root, 2-10 parts of madder and 10-12 parts of mulberry leaf.
4. The feed additive for rapidly improving the immunity of a swinery according to claim 3, wherein the traditional Chinese medicine powder additive comprises the following raw materials in parts by weight: 9 parts of astragalus, 2 parts of angelica, 8 parts of prepared rhizome of rehmannia, 5 parts of glossy privet fruit, 3 parts of schisandra fruit, 6 parts of dwarf lilyturf tuber, 4 parts of Chinese pulsatilla root, 10 parts of madder root and 12 parts of mulberry leaf.
5. The feed additive for rapidly enhancing the immunity of swinery according to claim 4, wherein the Chinese medicinal powder additive is prepared by fermenting folium mori, performing superfine grinding, and mixing with mixed extracts of the rest components.
6. The feed additive for rapidly improving the immunity of swinery according to claim 5, wherein the fermentation pretreatment of mulberry leaves is specifically as follows: cleaning, stalk removing and drying mulberry leaves collected after frost, then cutting, adding oxalic acid solution with the mass fraction of 2-4%, soaking for 2-4h, taking out, cleaning, drying and uniformly mixing with rapeseed cake to obtain a mixed material, adding cellulase with the mass fraction of 1-1.5% of the mixed material into the mixed material, stirring and uniformly mixing, heating to 50-60 ℃, keeping the temperature for 12-24h, adding complex enzyme for uniformly mixing, adding oxalic acid solution to adjust the pH value to 5-6, adding deionized water, stirring and uniformly mixing, fermenting for 4-7d at the temperature of 30-45 ℃, taking out and drying after fermentation to obtain the fermented mulberry leaves.
7. The feed additive for rapidly enhancing the immunity of swinery according to claim 6, wherein the complex enzyme comprises 1.2 x 109CFU/g Bacillus licheniformis, 2.2X 108CFU/g Saccharomyces cerevisiae, 1.2 × 108CFU/g Lactobacillus plantarum, 1.6X 109CFU/g lactobacillus.
8. The feed additive for rapidly improving the immunity of a swinery according to claim 7, wherein the preparation method of the traditional Chinese medicine powder additive specifically comprises the following steps:
s1: taking radix astragali, radix Angelicae sinensis, radix rehmanniae Preparata, fructus Ligustri Lucidi, fructus Schisandrae chinensis, radix Ophiopogonis, radix Pulsatillae and radix Rubiae according to the mass ratio, drying, parching with slow fire until fragrance overflows, taking out, naturally airing to normal temperature, adding into a bulking machine, performing high-pressure bulking treatment under the conditions of the temperature of 95-100 ℃ and the pressure of 6-8MPa, cooling to room temperature after the treatment is completed, taking out, grinding into powder to obtain mixed powder, adding ethanol solution with the mass of 6-8 times of the mixed powder into the mixed powder, soaking for 2-3h, performing ultrasonic extraction for 30-40min, filtering to obtain ultrasonic extract and ultrasonic extraction residue, performing low-temperature plasma treatment on the ultrasonic extraction residue, adding deionized water with the mass of 4-6 times of the ultrasonic extraction residue into a high-pressure kettle, decocting for 20-30min under high pressure, filtering to obtain high-pressure extract and high, mixing the ultrasonic extracting solution and the high-pressure extracting solution, concentrating under reduced pressure to obtain extract, and drying to obtain a mixed extract;
s2: drying fermented folium Mori in 60 deg.C drying oven for 2-3h, pulverizing in common pulverizer, sieving with 100 mesh sieve, pulverizing in ultramicro pulverizer, sieving with 300 mesh sieve, adding the mixed extract, stirring, and mixing to obtain Chinese medicinal powder additive.
9. The feed additive for rapidly enhancing the immunity of a swinery according to claim 8, wherein the particle size of the Chinese medicinal powder additive is 12-15 μm.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112586598A (en) * | 2020-12-17 | 2021-04-02 | 湖南百宜饲料科技有限公司 | Preparation method of biological feed for improving livestock and poultry production performance |
| CN115633735A (en) * | 2022-09-27 | 2023-01-24 | 翁源县新南都饲料科技有限公司 | Plant extract feed additive for preventing and treating porcine respiratory diseases and enhancing immunity |
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2020
- 2020-10-19 CN CN202011119624.7A patent/CN112401072A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112586598A (en) * | 2020-12-17 | 2021-04-02 | 湖南百宜饲料科技有限公司 | Preparation method of biological feed for improving livestock and poultry production performance |
| CN115633735A (en) * | 2022-09-27 | 2023-01-24 | 翁源县新南都饲料科技有限公司 | Plant extract feed additive for preventing and treating porcine respiratory diseases and enhancing immunity |
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