CN112295087A - Continuous slow-release drug-delivery analgesia drainage tube - Google Patents

Continuous slow-release drug-delivery analgesia drainage tube Download PDF

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Publication number
CN112295087A
CN112295087A CN202011187983.6A CN202011187983A CN112295087A CN 112295087 A CN112295087 A CN 112295087A CN 202011187983 A CN202011187983 A CN 202011187983A CN 112295087 A CN112295087 A CN 112295087A
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China
Prior art keywords
release
tube
drug
drainage tube
slow
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CN202011187983.6A
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CN112295087B (en
Inventor
夏敏
王胜
谭斌
吴舟
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Hefei Dami Medical Science & Technology Co ltd
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Hefei Dami Medical Science & Technology Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0017—Catheters; Hollow probes specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/0071—Multiple separate lumens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • External Artificial Organs (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention provides a continuous slow-release drug delivery analgesia drainage tube which comprises a drainage tube body, a slow-release tube and a drug storage bag, wherein the slow-release tube and the drainage tube body are connected into a whole, the slow-release tube extends along the extension direction of the drainage tube body, a drug injection port is formed in the drug storage bag, external drug liquid can enter the drug storage bag through the drug injection port, and the drug liquid in the drug storage bag can be forced into the slow-release tube and seeps out to the outer side of the slow-release tube through the tube wall of the slow-release tube. The continuous slow-release drug-delivery analgesia drainage tube can drain exudates and blood at the incision and can deliver analgesic drugs to the local part of the incision in a continuous slow-release manner so as to relieve incision pain and drainage tube irritation pain of patients.

Description

Continuous slow-release drug-delivery analgesia drainage tube
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a continuous slow-release drug delivery analgesia drainage tube.
Background
For many surgical patients, a drainage tube is often required to be reserved at an incision to drain exudates and blood, in order to relieve the incision pain and the stimulation pain of the drainage tube of a patient, local anesthetic is often injected at the incision once, but the patient feels severe pain after the drug is metabolized due to single administration, the drainage tube is an outward drainage device, the local anesthetic cannot be injected through a tube cavity to relieve the pain, and therefore the analgesic can only be applied to the whole body, and the systemic administration has the defects of poor effect, large side effect and the like.
Disclosure of Invention
Therefore, the technical problem to be solved by the invention is to provide a continuous slow-release drug-delivery analgesia drainage tube, which can deliver analgesic drugs to local incision parts in a sustained-release manner while draining exudates and blood at the incision so as to relieve incision pain and drainage tube irritation pain of patients.
In order to solve the problems, the invention provides a continuous slow-release drug delivery analgesia drainage tube, which comprises a drainage tube body, a slow-release tube and a drug storage bag, wherein the slow-release tube is connected with the drainage tube body into a whole, the slow-release tube extends along the extension direction of the drainage tube body, the drug storage bag is provided with a drug injection port, external drug liquid can enter the drug storage bag through the drug injection port, and the drug liquid in the drug storage bag can be forced into the slow-release tube and seeps out to the outer side of the slow-release tube through the tube wall of the slow-release tube.
Preferably, the medicine storage bag is made of an elastic material, so that the medicine liquid in the medicine storage bag is forced into the slow release tube by utilizing the elastic retraction of the medicine storage bag.
Preferably, the slow release tube is made of medical hydrophilic and hydrophobic nano composite materials.
Preferably, the medical hydrophilic and hydrophobic nanocomposite comprises one of a fluoropolymer and a polyurethane.
Preferably, the medicine storage bag is communicated with the slow release tube through a medicine injection tube.
Preferably, the drug injection tube is a flexible tube.
Preferably, the drug injection tube and the slow release tube are connected into a whole; and/or the medicine injection tube and the drainage tube body are clasped into a whole by adopting a hoop.
Preferably, a plurality of drainage holes are formed in the wall of the drainage tube body, and the drainage holes are arranged at intervals along the extending direction of the drainage tube body.
Preferably, one end of the drainage tube body in the target indwelling tissue is an open end; and/or one end of the slow release pipe, which is positioned in the target indwelling tissue, is a closed end.
Preferably, a check valve is arranged in the medicine injection port.
According to the continuous slow-release drug-administration analgesia drainage tube provided by the invention, through the combined action of the slow-release tube 2 and the drug storage bag 3, the purpose of draining exudates and blood at the incision is realized, meanwhile, analgesic drugs can be continuously and slowly administered to the local part of the incision, the incision pain and the drainage tube stimulation pain of a patient after the local anesthesia drug metabolism at the incision position of the patient in the prior art are effectively relieved, and the defects caused by the adoption of general anesthesia after the local anesthesia drug metabolism in the prior art are effectively overcome.
Drawings
Fig. 1 is a schematic structural diagram of a continuous sustained-release drug-delivery analgesia drainage tube according to an embodiment of the invention.
The reference numerals are represented as:
1. a drainage tube body; 11. a drainage hole; 2. a slow release tube; 3. a medicine storage bag; 31. a medicine injection port; 4. a medicine injection tube; 41. and (5) hooping.
Detailed Description
Referring to fig. 1, according to an embodiment of the present invention, there is provided a continuous sustained-release drug administration analgesia drainage tube, including a drainage tube body 1, a sustained-release tube 2, and a drug storage bag 3, wherein the sustained-release tube 2 is connected with the drainage tube body 1 as a whole, the sustained-release tube 2 extends along an extending direction of the drainage tube body 1, the drug storage bag 3 has a drug injection port 31 thereon, external drug liquid can enter the drug storage bag 3 through the drug injection port 31, and the drug liquid in the drug storage bag 3 can be forced into the sustained-release tube 2 and oozed out to the outside thereof through a tube wall of the sustained-release tube 2. In the technical scheme, through the combined action of the slow release tube 2 and the medicine storage bag 3, the effect of continuously and slowly releasing and giving analgesic medicines to incision parts while conducting drainage on exudates and blood at the incision part is achieved, incision pain and drainage tube irritation of patients after local anesthesia medicine metabolism at the incision position of the patients in the prior art are effectively relieved, and the defect caused by general anesthesia after the local anesthesia medicine metabolism in the prior art is effectively overcome.
Preferably, the drug storage bag 3 is made of an elastic material to force the drug solution in the drug storage bag 3 into the drug injection tube 4 by utilizing the elastic retraction of the drug storage bag itself, it is understood that the elastic material should be a medical material, and the elastic force should be selected to match the seepage rate of the slow release tube 2 to prevent the drug solution from seeping out too fast or too slow in the drug administration process. The slow release tube 2 is made of medical hydrophilic and hydrophobic nano composite materials, specifically, the medical hydrophilic and hydrophobic nano composite materials can comprise one of fluorine-containing macromolecules and polyurethane, and the pore diameter of a permeation hole on the slow release membrane is 1-100 nm. It is further noted that the cooperation of the elastic medicine storage bag 3 and the slow release tube 2 makes the administration more durable and uniform.
Preferably, the medicine storage bag 3 is made of an elastic material, and specifically, for example, one of silica gel, rubber, latex or nylon can be used, wherein the formable wall thickness of the silica gel is 0.2-0.4mm, the shore softness is 30, the medicine storage bag can be manufactured by injection molding or bonding technology, the elasticity is good, the product performance is stable, the medicine storage bag is transparent, and the medicine storage bag can be beneficial for an operator to observe the liquid medicine condition in the bag; the formable wall thickness of the rubber is 0.5-0.8mm, the Shore softness is 40, the formable wall can be manufactured by adopting an injection molding or bonding process, the formable wall has general elasticity, the appearance is rough, the hardness is high, the formable wall is mostly white, and the liquid medicine condition in the capsule can not be observed; the formable wall thickness of the latex is 0.2-1mm, the Shore softness is 20-30, the formable latex can be manufactured by adopting an injection molding or bonding process, the formable latex has moderate elasticity, the appearance is not fine and smooth enough, the formable latex is semitransparent, and the forming effect is not good; the wall thickness of the formable nylon is 0.2-0.6mm, the formable nylon can be manufactured by adopting a bonding process, the formable nylon has poor elasticity and is semitransparent, and therefore, the formable nylon is best, and the medicine storage bag 3 is made of silica gel.
Preferably, the medicine storage bag 3 is communicated with the slow release tube 2 through a medicine injection tube 4, and most preferably, the medicine injection tube 4 is a flexible tube, which can facilitate the selection of the medicine administration angle of medical staff when the medicine is administered into the medicine storage bag 3.
Further, the medicine injection tube 4 and the slow release tube 2 are connected into a whole to prevent the liquid medicine from leaking at the joint; and/or the medicine injection tube 4 and the drainage tube body 1 are clasped together by the hoop 41, so that the medicine storage bag 3 can be detached when slow release medicine administration is not needed, and the medicine injection tube 4 and the drainage tube body 1 are reliably connected by the hoop 41 when the slow release medicine administration is needed.
The drainage tube comprises a drainage tube body 1 and is characterized in that a plurality of drainage holes 11 are formed in the tube wall of the drainage tube body 1, the drainage holes 11 are arranged at intervals along the extending direction of the drainage tube body 1 so as to improve the drainage capacity of the drainage tube body 1, one end, located in a target indwelling tissue, of the drainage tube body 1 is an open end, and one end, located outside the target indwelling tissue, of the drainage tube body is used for being connected with a negative pressure suction device. It can be understood that the end of the slow release pipe 2 in the target indwelling tissue is a closed end, so as to ensure the slow release seepage effect of the liquid medicine in the slow release pipe.
A check valve is arranged in the medicine injection port 31 to prevent the backflow and leakage of the medicine liquid.
As a more preferable embodiment, the periphery of the slow release tube 2 may be optionally sleeved with a slow release positioning film sleeve (not shown in the figure), the slow release positioning film sleeve outside the through hole can prevent the liquid medicine in the slow release tube 2 from seeping out, and the through hole can allow the liquid medicine in the slow release tube 2 to seep out, so that the liquid medicine seeping out from the slow release tube 2 can be positioned, and the slow release positioning film sleeve is suitable for the situation that the continuous administration is required for some point-like focuses.
It is readily understood by a person skilled in the art that the advantageous ways described above can be freely combined, superimposed without conflict.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention. The above is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several improvements and modifications can be made without departing from the technical principle of the present invention, and these improvements and modifications should also be regarded as the protection scope of the present invention.

Claims (10)

1. The utility model provides a continuous slow-release analgesia drainage tube that doses, its characterized in that, includes drainage tube body (1), slowly-releasing pipe (2), medicine storage bag (3), slowly-releasing pipe (2) with drainage tube body (1) are connected as an organic whole just slowly-releasing pipe (2) extend along the extending direction of drainage tube body (1), medicine injection mouth (31) have on medicine storage bag (3), and outside liquid medicine can be via medicine injection mouth (21) gets into in medicine storage bag (3), the liquid medicine in medicine storage bag (3) can be compelled into in slowly-releasing pipe (2) and via the pipe wall of slowly-releasing pipe (2) oozes to its outside.
2. The continuous sustained-release drug delivery analgesia drainage tube according to claim 1, wherein the drug storage bag (3) is made of an elastic material so as to utilize the elastic retraction of the drug storage bag (3) to force the liquid medicine in the drug storage bag into the sustained-release tube (2).
3. The continuous sustained-release drug delivery analgesia drainage tube according to claim 1, characterized in that the sustained-release tube (2) is made of medical hydrophilic and hydrophobic nano composite material.
4. The continuous sustained-release drug delivery analgesia drainage tube of claim 3, wherein the medical hydrophilic and hydrophobic nano composite material comprises one of fluorine-containing polymer and polyurethane.
5. The continuous slow-release drug-delivery analgesia drainage tube according to claim 1, characterized in that the drug storage bag (3) is communicated with the slow-release tube (2) through a drug injection tube (4).
6. The continuous sustained-release drug delivery analgesia drain according to claim 5, wherein the drug injection tube (4) is a flexible tube.
7. The continuous slow-release drug delivery analgesia drainage tube according to claim 5, characterized in that the drug injection tube (4) is connected with the slow-release tube (2) into a whole; and/or the medicine injection tube (4) and the drainage tube body (1) are clasped together by adopting a hoop (41).
8. The continuous slow-release drug-delivery analgesia drainage tube according to claim 1, wherein a plurality of drainage holes (11) are formed in the tube wall of the drainage tube body (1), and the drainage holes (11) are arranged at intervals along the extension direction of the drainage tube body (1).
9. The continuous slow-release drug-delivery analgesia drain tube according to claim 1, wherein one end of the drain tube body (1) in the target indwelling tissue is an open end; and/or one end of the slow release pipe (2) in the target indwelling tissue is a closed end.
10. The continuous sustained-release drug delivery analgesia drainage tube according to claim 1, characterized in that a check valve is arranged in the drug injection port (21).
CN202011187983.6A 2020-10-29 2020-10-29 Continuous slow-release administration analgesic drainage tube Active CN112295087B (en)

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Application Number Priority Date Filing Date Title
CN202011187983.6A CN112295087B (en) 2020-10-29 2020-10-29 Continuous slow-release administration analgesic drainage tube

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CN112295087B CN112295087B (en) 2023-06-06

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989003232A1 (en) * 1987-10-09 1989-04-20 Bukh Meditec A/S A medical device for introduction into a body cavity
CN203090197U (en) * 2013-02-01 2013-07-31 海盐康源医疗器械有限公司 Silica gel urethral catheter with automatic controlled-release doser
CN105031800A (en) * 2015-08-31 2015-11-11 南京医科大学第一附属医院 Medical painless chest drainage pipe
US20170021128A1 (en) * 2015-07-20 2017-01-26 Strataca Systems, LLC Ureteral and Bladder Catheters and Methods of Inducing Negative Pressure to Increase Renal Perfusion
CN108136157A (en) * 2015-07-20 2018-06-08 斯卓特凯系统有限责任公司 Cause the conduit device and method of negative pressure in patient's bladder
CN208823748U (en) * 2017-12-05 2019-05-07 江苏大学附属医院 A kind of drainage device having analgesia function
CN210009404U (en) * 2019-04-08 2020-02-04 大理大学第一附属医院 Improvement type glaucoma aqueous humor drainage tube

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989003232A1 (en) * 1987-10-09 1989-04-20 Bukh Meditec A/S A medical device for introduction into a body cavity
CN203090197U (en) * 2013-02-01 2013-07-31 海盐康源医疗器械有限公司 Silica gel urethral catheter with automatic controlled-release doser
US20170021128A1 (en) * 2015-07-20 2017-01-26 Strataca Systems, LLC Ureteral and Bladder Catheters and Methods of Inducing Negative Pressure to Increase Renal Perfusion
CN108136157A (en) * 2015-07-20 2018-06-08 斯卓特凯系统有限责任公司 Cause the conduit device and method of negative pressure in patient's bladder
CN105031800A (en) * 2015-08-31 2015-11-11 南京医科大学第一附属医院 Medical painless chest drainage pipe
CN208823748U (en) * 2017-12-05 2019-05-07 江苏大学附属医院 A kind of drainage device having analgesia function
CN210009404U (en) * 2019-04-08 2020-02-04 大理大学第一附属医院 Improvement type glaucoma aqueous humor drainage tube

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