CN112169072A - Continuous slow-release administration indwelling tube - Google Patents

Continuous slow-release administration indwelling tube Download PDF

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Publication number
CN112169072A
CN112169072A CN202011183334.9A CN202011183334A CN112169072A CN 112169072 A CN112169072 A CN 112169072A CN 202011183334 A CN202011183334 A CN 202011183334A CN 112169072 A CN112169072 A CN 112169072A
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CN
China
Prior art keywords
tube
release
slow
drug
storage bag
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Pending
Application number
CN202011183334.9A
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Chinese (zh)
Inventor
夏敏
王胜
谭斌
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Anhui Provincial Hospital First Affiliated Hospital of USTC
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Anhui Provincial Hospital First Affiliated Hospital of USTC
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Publication date
Application filed by Anhui Provincial Hospital First Affiliated Hospital of USTC filed Critical Anhui Provincial Hospital First Affiliated Hospital of USTC
Priority to CN202011183334.9A priority Critical patent/CN112169072A/en
Publication of CN112169072A publication Critical patent/CN112169072A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention provides a continuous slow-release administration indwelling tube which comprises a slow-release tube body with a hollow tube cavity, a drug injection tube and a drug storage bag, wherein the slow-release tube body is provided with a first tube wall and a second tube wall positioned on the outer side of the first tube wall, the second tube wall is a slow-release film, a slow-release cavity is formed between the first tube wall and the second tube wall, the slow-release cavity is communicated with the drug storage bag through the drug injection tube, the drug storage bag is provided with a drug injection port, external drug liquid can enter the drug storage bag through the drug injection port, and then enters the slow-release cavity through the drug injection tube and seeps out to the outer side of the slow-release tube through the second tube wall. The continuous slow-release drug administration indwelling tube avoids repeated puncture on patients needing multiple drug administrations, does not need to puncture the patients with wide drug administration range at multiple points, reduces pain of the patients in the medical treatment process, and improves the medical experience of the patients.

Description

Continuous slow-release administration indwelling tube
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a continuous slow-release drug administration indwelling tube.
Background
For many patients with sports injury, a local nerve blocking method is often needed to relieve pain and eliminate inflammation, and for some patients with substantial tumors, a tumor body injection method can be used to kill tumor cells. However, the prior art only can carry out single administration, and patients who need to carry out multiple administrations have to puncture repeatedly, which undoubtedly increases the pain of the patients; in addition, during administration, the medicine only can be intensively effused from the outlet of the administration tube, and the medicine is often gathered at the outlet and can not be diffused to a sufficiently far area, so that for some patients needing wide administration range, the medicine has to be administered by multi-point puncture, and for the patients adopting percutaneous puncture area continuous administration treatment (such as analgesia, chemotherapy and the like), the invention is provided on the basis that the long-time uniform local administration can not be realized in a good mode.
Disclosure of Invention
Therefore, the technical problem to be solved by the invention is to provide a continuous slow-release drug administration indwelling tube, which avoids repeated puncture on a patient needing multiple drug administrations, does not need to puncture the patient at multiple points with a wide drug administration range, reduces pain of the patient in the medical treatment process, and improves the medical experience of the patient.
In order to solve the above problems, the present invention provides a continuous sustained-release drug delivery indwelling tube, which comprises a sustained-release tube body having a hollow tube cavity, a drug injection tube, and a drug storage bag, wherein the sustained-release tube body has a first tube wall and a second tube wall located outside the first tube wall, the second tube wall is a sustained-release film, a sustained-release cavity is formed between the first tube wall and the second tube wall, the sustained-release cavity is communicated with the drug storage bag through the drug injection tube, the drug storage bag has a drug injection port, and external drug solution can enter the drug storage bag through the drug injection port, and then enter the sustained-release cavity through the drug injection tube and seep out to the outside of the sustained-release tube through the second tube wall.
Preferably, the medicine storage bag is made of an elastic material, so that the medicine liquid in the medicine storage bag is forced into the slow release cavity by utilizing the elastic retraction of the medicine storage bag.
Preferably, a check valve is arranged in the medicine injection port.
Preferably, the slow release membrane is made of medical hydrophilic and hydrophobic nano composite materials.
Preferably, the medical hydrophilic and hydrophobic nanocomposite comprises one of a fluoropolymer and a polyurethane.
Preferably, the continuous slow-release drug administration indwelling tube further comprises a puncture inner core, and the puncture inner core can penetrate through the hollow lumen.
Preferably, the first end of the plunger has a syringe interface.
Preferably, the drug injection tube is communicated with the drug storage bag through a connecting tube, and the connecting tube is a flexible tube.
Preferably, the drug injection tube and the slow release tube body are connected into a whole.
According to the continuous slow-release drug delivery indwelling tube provided by the invention, through the design of the drug storage bag and the slow-release cavity, medical staff can puncture once to achieve the purposes of multi-point puncture and repeated puncture in the prior art, liquid medicine in the drug storage bag, the drug injection tube and the slow-release cavity can slowly permeate and seep to indwelling target tissues of a patient through the second tube wall, the tube length of the slow-release cavity can cover a larger drug delivery area, and the patient with a wide drug delivery range does not need to puncture at multiple points and repeatedly, so that the pain of the patient in the medical treatment process is reduced, and the medical experience of the patient is improved.
Drawings
FIG. 1 is a schematic structural view of an indwelling tube for continuous sustained release drug delivery in accordance with an embodiment of the present invention.
The reference numerals are represented as:
1. a slow release tube body; 11. a first tube wall; 12. a second tube wall; 13. a sustained release chamber; 2. a medicine injection tube; 21. a connecting pipe; 3. a medicine storage bag; 31. a medicine injection port; 4. puncturing the inner core; 41. an injector interface.
Detailed Description
Referring to fig. 1, according to an embodiment of the present invention, a continuous sustained-release drug delivery indwelling tube is provided, including a sustained-release tube body 1 having a hollow tube cavity, a drug injection tube 2, and a drug storage bag 3, where the sustained-release tube body 1 has a first tube wall 11 and a second tube wall 12 located outside the first tube wall 11, where the second tube wall 12 is a sustained-release film, a sustained-release cavity 13 is formed between the first tube wall 11 and the second tube wall 12, the sustained-release cavity 13 is communicated with the drug storage bag 3 through the drug injection tube 2, the drug storage bag 3 has a drug injection port 31 thereon, and external drug solution can enter the drug storage bag 3 through the drug injection port 31, and then enter the sustained-release cavity 13 through the drug injection tube 2 and seep out to the outside through the second tube wall 12. In this technical scheme, through store up medicine bag 3 with the design of slowly-releasing chamber 13 makes medical personnel can only puncture once just can realize the purpose of multiple spot puncture among the prior art, puncture repeatedly, is in the liquid medicine that stores up medicine bag 3, injection pipe 2 and slowly-releasing chamber 13 can pass through the slow infiltration of second pipe wall 12 oozes to the target tissue of keeping somewhere of disease, just the pipe length of slowly-releasing chamber 13 can cover great administration area, need not to puncture, puncture repeatedly to the wide patient multiple spot of scope of dosing to reduce the misery of disease medical procedure, improved the experience of seeking medical advice of disease. It can be understood that the first tube wall 11 is made of an impermeable film, so as to prevent the liquid medicine from permeating into the hollow cavity of the sustained release tube body 1.
Preferably, the medicine storage bag 3 is made of an elastic material, so that the medicine liquid in the medicine storage bag 3 is forced into the slow release cavity 13 by the elastic retraction of the medicine storage bag 3, and the medicine liquid in the medicine injection tube 2 is forced into the slow release cavity 13 by the elastic retraction of the medicine storage bag 3, and it can be understood that the elastic material is a medical material, and the elastic material is matched with the seepage rate of the slow release cavity 13 in terms of the selection of the elastic force, so that the medicine liquid is prevented from seeping out too fast or too slow in the administration process. The slow release membrane is made of medical hydrophilic and hydrophobic nano composite materials, specifically, the medical hydrophilic and hydrophobic nano composite materials can comprise one of fluorine-containing macromolecules and polyurethane, and the pore diameter of a permeation hole on the slow release membrane is 1-100 nm. It is further noted that the cooperation of the elastic medicine storage bag 3 and the slow release cavity 13 makes the administration more durable and uniform.
Preferably, the medicine storage bag 3 is made of an elastic material, and specifically, for example, one of silica gel, rubber, latex or nylon can be used, wherein the formable wall thickness of the silica gel is 0.2-0.4mm, the shore softness is 30, the medicine storage bag can be manufactured by injection molding or bonding technology, the elasticity is good, the product performance is stable, the medicine storage bag is transparent, and the medicine storage bag can be beneficial for an operator to observe the liquid medicine condition in the bag; the formable wall thickness of the rubber is 0.5-0.8mm, the Shore softness is 40, the formable wall can be manufactured by adopting an injection molding or bonding process, the formable wall has general elasticity, the appearance is rough, the hardness is high, the formable wall is mostly white, and the liquid medicine condition in the capsule can not be observed; the formable wall thickness of the latex is 0.2-1mm, the Shore softness is 20-30, the formable latex can be manufactured by adopting an injection molding or bonding process, the formable latex has moderate elasticity, the appearance is not fine and smooth enough, the formable latex is semitransparent, and the forming effect is not good; the wall thickness of the formable nylon is 0.2-0.6mm, the formable nylon can be manufactured by adopting a bonding process, the formable nylon has poor elasticity and is semitransparent, and therefore, the formable nylon is best, and the medicine storage bag 3 is made of silica gel.
Preferably, a check valve is provided in the injection port 31 to prevent backflow of the medical fluid.
Furthermore, the continuous slow-release administration indwelling tube also comprises a puncture inner core 4, wherein the puncture inner core 4 can penetrate through the hollow tube cavity, namely the puncture inner core 4 can be pulled out of the hollow tube cavity or inserted into the hollow tube cavity, so that the percutaneous puncture process of the indwelling tube is facilitated. Preferably, the drug injection tube 2 and the sustained-release tube body 1 are connected into a whole to prevent the drug solution from leaking at the joint. The interface between the drug injection tube 2 and the sustained-release tube body 1 should be positioned in the target indwelling tissue when the indwelling tube is applied to prevent the drug solution from being externally infiltrated to the outside of the skin of the human body when sustained-release drug delivery is performed.
The puncture inner core 4 is made of hard medical material, and a syringe interface 41 is further arranged at the first end (namely, the end positioned outside the human body) of the puncture inner core so as to be connected with a syringe to directly inject liquid medicine through the puncture inner core.
Preferably, the drug injection tube 2 is communicated with the drug storage bag 3 through a connecting tube 21, the connecting tube 21 is a flexible tube, and the connecting tube 21 has flexibility, which facilitates the selection of the drug administration angle of the medical staff when the drug is administered into the drug storage bag 3.
As a more preferable embodiment, the periphery of the sustained release tube body 1 can be optionally sleeved with a sustained release positioning film sleeve (not shown in the figure), the sustained release positioning film sleeve is provided with a through hole, the sustained release positioning film sleeve outside the through hole can prevent the liquid medicine in the sustained release tube body 1 from seeping out, and the through hole can allow the liquid medicine in the sustained release tube body 1 to seep out, so that the liquid medicine seeping out in the sustained release tube body 1 can be positioned, and the sustained release tube body is suitable for the situation that the sustained drug delivery is required for some point-like focuses.
It is readily understood by a person skilled in the art that the advantageous ways described above can be freely combined, superimposed without conflict.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention. The above is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several improvements and modifications can be made without departing from the technical principle of the present invention, and these improvements and modifications should also be regarded as the protection scope of the present invention.

Claims (9)

1. The utility model provides a keep somewhere pipe in continuous slowly-releasing dosing which characterized in that, is including the slowly-releasing body (1), injection pipe (2), the medicine storage bag (3) that have the cavity lumen, slowly-releasing body (1) have first pipe wall (11) and be in second pipe wall (12) in first pipe wall (11) outside, wherein second pipe wall (12) are the slow-release membrane, first pipe wall (11) with form slowly-releasing chamber (13) between second pipe wall (12), slowly-releasing chamber (13) pass through injection pipe (2) with medicine storage bag (3) intercommunication, medicine storage bag (3) are last to have injection mouth (31), and outside liquid medicine can get into via injection mouth (31) in medicine storage bag (3), and then via injection pipe (2) get into slowly-releasing chamber (13) and ooze to its outside via second pipe wall (12).
2. The indwelling tube for continuous sustained-release drug delivery according to claim 1, wherein the drug reservoir (3) is made of an elastic material to force the drug solution therein into the sustained-release lumen (13) by elastic recoil of the drug reservoir (3) itself.
3. The indwelling catheter for continuous slow release drug delivery according to claim 2, wherein a check valve is provided in the drug injection port (31).
4. The indwelling catheter for continuous slow-release drug delivery according to claim 1, wherein the slow-release membrane is made of medical hydrophilic and hydrophobic nano-composite materials.
5. The indwelling tube for continuous slow release drug delivery according to claim 4, wherein the medical hydrophilic and hydrophobic nanocomposite comprises one of fluoropolymer and polyurethane.
6. The continuous slow release drug delivery indwelling tube according to any one of claims 1 to 5, further comprising a puncture inner core (4), the puncture inner core (4) being capable of passing through the hollow lumen.
7. The indwelling catheter for continuous slow release drug delivery according to claim 6, wherein the first end of the piercing core (4) has a syringe port (41).
8. The indwelling tube for continuous sustained release drug delivery according to claim 1, wherein the drug injection tube (2) is in communication with the drug reservoir (3) through a connecting tube (21), the connecting tube (21) being a flexible tube.
9. The continuous slow-release drug delivery indwelling tube according to claim 8, wherein the drug injection tube (2) is integrally connected with the slow-release tube body (1).
CN202011183334.9A 2020-10-29 2020-10-29 Continuous slow-release administration indwelling tube Pending CN112169072A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011183334.9A CN112169072A (en) 2020-10-29 2020-10-29 Continuous slow-release administration indwelling tube

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011183334.9A CN112169072A (en) 2020-10-29 2020-10-29 Continuous slow-release administration indwelling tube

Publications (1)

Publication Number Publication Date
CN112169072A true CN112169072A (en) 2021-01-05

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CN202011183334.9A Pending CN112169072A (en) 2020-10-29 2020-10-29 Continuous slow-release administration indwelling tube

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102488958A (en) * 2011-12-21 2012-06-13 陆晓燕 Implanted chemical therapy device for abdominal cavity
CN105617511A (en) * 2016-03-09 2016-06-01 复旦大学附属金山医院 Non-deforming continuous peripheral nerve blocking indwelling catheter
CN108671352A (en) * 2018-05-21 2018-10-19 南阳市第二人民医院 A kind of trachea cannula
CN210009404U (en) * 2019-04-08 2020-02-04 大理大学第一附属医院 Improvement type glaucoma aqueous humor drainage tube
CN111330137A (en) * 2018-12-17 2020-06-26 深圳市擎源医疗器械有限公司 Drug delivery device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102488958A (en) * 2011-12-21 2012-06-13 陆晓燕 Implanted chemical therapy device for abdominal cavity
CN105617511A (en) * 2016-03-09 2016-06-01 复旦大学附属金山医院 Non-deforming continuous peripheral nerve blocking indwelling catheter
CN108671352A (en) * 2018-05-21 2018-10-19 南阳市第二人民医院 A kind of trachea cannula
CN111330137A (en) * 2018-12-17 2020-06-26 深圳市擎源医疗器械有限公司 Drug delivery device
CN210009404U (en) * 2019-04-08 2020-02-04 大理大学第一附属医院 Improvement type glaucoma aqueous humor drainage tube

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