CN205814863U - A kind of micropin dosing paster containing separate type medicine storing bag - Google Patents
A kind of micropin dosing paster containing separate type medicine storing bag Download PDFInfo
- Publication number
- CN205814863U CN205814863U CN201620619911.7U CN201620619911U CN205814863U CN 205814863 U CN205814863 U CN 205814863U CN 201620619911 U CN201620619911 U CN 201620619911U CN 205814863 U CN205814863 U CN 205814863U
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- Prior art keywords
- medicine
- micropin
- storing bag
- separate type
- medicine storing
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Abstract
This utility model discloses a kind of flexible micropin dosing paster containing separate type medicine storing bag, it is adaptable to the transdermal delivery of multi-medicament, the feature such as possess that pain is low, infection risk is low and application is convenient.This utility model includes: an interchangeable medicine storing bag of separate type, integrate microneedle array and the medicine carrying end of microfluidic channel network, integrate microneedle array and the loading end of microfluidic channel network and adhesive patches micropin dosing paster can being attached on skin for one for one.Adhesive patches is made up of flexible polymer, and bendable curvature is high and strong to the stickiness of skin.During use, dosing paster is attached at user joint, extruding and the stretching of flexible dosing paster are made the medicine carrying end of dosing paster and medicine storing bag deform upon by the bending utilizing joint, so that the syringe needle of medicine carrying end thrusts medicine storing bag, and pass through microfluidic channel network by medicament distribution to loading end；Then the passage formed on skin by the micropin of loading end is flowed into human body and completes loading.
Description
Technical field
This utility model relates to a kind of transdermal infusion device, particularly relates to a kind of micropin containing separate type medicine storing bag to plaster
Sheet.
Background technology
Drug therapy is a kind of common medical procedure, and medicine enters the main mode of movement of human body and includes injection and mouth
Clothes, both modes all have some limitations.Medicine is likely to be due to oneself's metabolism in oral period and inactivates thus lose
Curative effect；Subcutaneous injection needs trained personnel to implement, and brings unavoidable pain and infection to sufferer
Risk, make troubles to patient.In recent years, micropin administering mode increasingly attracts the concern of people.Micropin is a kind of similar
The micron order of injection needle is hollow or solid needle, typically uses single crystal silicon material, metal or high molecular polymer to be made.It
Just can not touch pain nerve through horny layer, do not create a painful feeling and skin corium playing drug osmotic effect simultaneously
Damage.
Solid microneedles can be divided into medicine carrying solid microneedles and not medicine carrying solid microneedles two class.
Wherein medicine carrying solid microneedles uses and first wraps the administering mode pricked afterwards, i.e. remakes after packaging medicine on the outer wall of micropin
Making drug molecule discharge for skin, the drug-supplying system of this form does not has drug-reservoir, punctures keratodermatitis at micropin
Medicine is passed in human body by synchronization simultaneously, is directly released into targeted cells or infected tissue；Medicine carrying micropin is not adopted
With first pricking the administering mode pasted afterwards, after i.e. micropin acts on skin, horny layer produces micron-sized hole, thus sets up big
Measuring micron-sized micro-channel, then use medicine patch, medicine will be directed to internal by micro-channel.
Although solid microneedles has many advantages, but is not widely used in medical practice.Medicine carrying solid microneedles
Drug loading is the lowest, can affect the acutance of needle body after packaging medicine, and needle body can be caused can not to thrust skin smoothly.Medicine carrying is not solid micro-
After pin acts on skin, can temporarily break the barrier action of keratodermatitis, set up substantial amounts of skin micro-channel.But micropin
After removing, along with the recovery of stratum corneum barrier function while skin recovery normal condition, this can stop medicine to continue to pass through
Skin, so the active drug conveying capacity that medicine carrying solid microneedles can not realize is extremely limited.
At present, compared to solid microneedles, empty micropin is considered as one more promising micropin drug delivery structure.Hollow micro-
Pin is the form conveying medicine using microinjection, comprises the hollow channel of a micron level inside the needle body of empty micropin,
Under the driving of flow stream pressure, medicine can be carried by hollow channel.Empty micropin not only can realize the biggest
The medicine conveying of dosage, and the acutance of empty micropin needle body can also be maintained in the level effectively puncturing keratodermatitis.
Above-mentioned advantage based on empty micropin, this utility model devise a kind of flexible micropin containing separate type medicine storing bag to
Medicine plaster, the micropin in dosing paster have employed empty micropin, it is ensured that realizes in the case of effectively puncturing keratodermatitis
Lasting medicine conveying, thus increase the conveying capacity of medicine.It addition, dosing paster described in the utility model uses flexible biological material
Material is made as substrate, it is ensured that the skin-friendly of dosing paster, is suitable to human body laminating skin and uses.What is more important, this reality
Have employed the design of separate type medicine storing bag with novel described dosing paster, medicine storing bag can be replaced according to different drug delivery demands,
Thus greatly improve the versatility of dosing paster described in the utility model.
Utility model content
This utility model describes a kind of a kind of flexible micropin containing separate type medicine storing bag made based on polymer and is administered
Paster.Described in utility model, a kind of flexible micropin dosing paster containing separate type medicine storing bag includes: a separate type is interchangeable
Medicine storing bag；Integrate microneedle array and the medicine carrying end of microfluidic channel network for one；Integrate microneedle array and microfluidic channel for one
The loading end of network and adhesive patches micropin dosing paster can being attached on skin.
A kind of flexible micropin dosing paster containing separate type medicine storing bag described in the utility model is made up of flexible polymer,
Can well bend.Be attached at user joint during use, utilize the bending in joint to the extruding of flexible dosing paster and
Stretching makes the medicine carrying end of dosing paster and medicine storing bag deform upon, so that the syringe needle of medicine carrying end thrusts medicine storing bag, and leads to
Cross microfluidic channel network by medicament distribution to loading end；Then the passage formed on skin by the micropin of loading end is flowed into
Human body completes loading.
A kind of flexible micropin dosing paster feature containing separate type medicine storing bag described in the utility model is:
1. dimethyl siloxane (PDMS) is made up by overall structure of flexible polymer, has the characteristic of flexibility, pro-skin；
2. the control of loading is to be completed by the joint motions of user, relies on arthrogryposis to squeeze loading paster generation
Pressure and stretching make medicine carrying end microneedle array puncture medicine storing bag, start the conveying of medicine；
3. the conveying of medicine is that the closing microfluidic channel by being integrated in flexible substrates completes；
4. medicine storing bag is separate type, can be replaced according to the demand of the medicine of conveying；
5. the micropin of medicine carrying end and loading end is internal containing being available for the passage that medicine circulates, and medicine can be by inside micropin
Passage flow into microfluidic channel network carry；
6. use SU-8 photoresist to make micropin to puncture skin and carry out medicine conveying.
A kind of flexible micropin dosing paster containing separate type medicine storing bag described in the utility model has a following benefit:
Dosing paster bio-compatibility the most described in the utility model is good, is not result in the untoward reaction such as allergy；
Dosing paster the most described in the utility model is flexible, skin of can well fitting, and wear comfort is high；
Micropin on dosing paster the most described in the utility model is hollow, and medicine can be avoided to be contaminated；
Dosing paster the most described in the utility model uses micropin to carry out loading, the superinfection reduce misery, avoiding
Risk, and use simple, ordinary people also can easily use；
The drug storage part of dosing paster the most described in the utility model is separate type, can adaptive different loading demand,
Easy to use；
Dosing paster the most described in the utility model uses the microfluidic channel closed to carry out medicine conveying, can avoid medicine
Pollution in transmitting procedure.
Accompanying drawing explanation
Fig. 1 is a kind of micropin dosing paster overall schematic containing separate type medicine storing bag.
Fig. 2 is separate type medicine storing bag side view.
Fig. 3 is separate type medicine storing bag top view.
Fig. 4 is separate type medicine storing bag upward view.
Fig. 5 is the medicine carrying end-view of micropin dosing paster.
Fig. 6 is the medicine carrying end top view of micropin dosing paster.
Fig. 7 is the loading end-view of micropin dosing paster.
Fig. 8 is the loading end upward view of micropin dosing paster.
Fig. 9 is that a kind of micropin dosing paster containing separate type medicine storing bag is applied to the schematic diagram on elbow joint.
Detailed description of the invention
This utility model is achieved through the following technical solutions:
A kind of flexible micropin dosing paster containing separate type medicine storing bag described in the utility model, as it is shown in figure 1, include:
One interchangeable medicine storing bag of separate type 1；Integrate microneedle array and the medicine carrying end 2 of microfluidic channel network for one；One integration
The loading end 3 of microneedle array and microfluidic channel network, and adhesive patches micropin dosing paster can being attached on skin
4.For the simplicity described, the one side of contact skin is referred to as " bottom surface " by this utility model, another side is referred to as " end face ".
A kind of interchangeable medicine storing bag of separate type 1 described in the utility model, is made by dimethyl siloxane (PDMS),
Such as Fig. 2, shown in 3 and 4, including a flexible substrates 5, the drug storage space 6 of an elliposoidal, a limit being positioned at medicine storing bag bottom surface
Frame 7 and the viscosity being produced on frame lower surface connect sheet 8.Wherein: flexible substrates 5 maintains the interchangeable medicine storing bag of whole separate type
1 Stability Analysis of Structures；Elliposoidal drug storage space 6 is for storing the medicine of required injection；Frame 7 is used for isolating drug storage space 6 and medicine carrying
The microneedle array 12 of end 2, to avoid, the microneedle array 12 when not using this paster is unexpected pokes drug storage space 6；It is produced on frame 7
Viscosity on end face connects the sheet 8 bonding for the interchangeable medicine storing bag of separate type described in utility model 1 with medicine carrying end 2.
Further, viscosity connection sheet 8 surface being produced on medicine storing bag frame lower surface described in the utility model covers
One layer of release paper 9.
Medicine carrying end 2 described in the utility model, as it can be seen in figures 5 and 6, include a flexible substrates 10, one is integrated in base
Microfluidic channel network 11 at the end 10, one that be connected with microfluidic channel network 11, be positioned at the 5 × 5 of medicine carrying end 2 end face
Microneedle array 12, a frame 15 being positioned at medicine carrying end 2 end face connects sheet 13 with the viscosity being produced on frame 15 upper surface.Its
In, flexible substrates 10 is the main body of flexible micropin dosing paster described in the utility model, for maintaining whole dosing paster
Stability Analysis of Structures；Microfluidic channel network 11 is for being delivered to loading end 3 by medicine from medicine carrying end 2；Microneedle array 12 is used for puncturing
Medicine storing bag 1；Frame 15 is for isolating the microneedle array 12 of drug storage space 6 and medicine carrying end, to avoid not using this utility model
During described paster, microneedle array 12 is unexpected pokes medicine storing bag 1；The viscosity being produced on frame 15 end face connects sheet 13 for practicality
The novel interchangeable medicine storing bag of described separate type 1 and the bonding of medicine carrying end 2.
Further, viscosity connection sheet 13 surface being produced on medicine carrying end 2 frame 15 upper surface described in the utility model is covered
Cover one layer of release paper 14.
Loading end 3 described in the utility model, as shown in FIG. 7 and 8, is in same substrate 10 with medicine carrying end 2, also wraps
Included a microfluidic channel network being integrated within substrate 10 16, one that be connected with microfluidic channel network 16, be positioned at
5 × 5 microneedle arrays 17 of loading end 3 bottom surface.Wherein: microfluidic channel network 16 is delivered to loading for receiving from medicine carrying end 2
Hold the medicine of 3 and distribute to each syringe needle of microneedle array 17；Microneedle array 17 is used for puncturing skin, and formation is available for medicine and oozes
Saturating passage.
Adhesive patches 4 described in the utility model, is positioned at the bottom surface of flexible micropin dosing paster containing separate type medicine storing bag
18, cover other parts in addition to loading end microneedle array 17 position, adhesive patches 4 surface covers one layer before use
Release paper 19.
Further, two 5 × 5 microneedle arrays described in the utility model are made by SU-8 photoresist.
A kind of micropin dosing paster occupation mode containing separate type medicine storing bag described in the utility model is as follows:
1., before using, medicine storing bag and dosing paster are to separate；
When 2. preparing to use, the release paper 9 of medicine storing bag 1 bottom surface of tearing and the release paper 14 of dosing paster medicine carrying end 2 end face,
And medicine storing bag 1 is connected with the medicine carrying end 2 of dosing paster；
Tear the most subsequently the release paper 19 of dosing paster bottom surface；
Being attached at user joint when 4. using, medicine carrying end 2 is positioned at arthrogryposis, as shown in Figure 9；
5. when arthrogryposis, can be to the extruding of flexible dosing paster and stretching so that the medicine carrying end 2 of dosing paster and storage
Medicine bag 1 deforms upon, so that the microneedle array 12 of medicine carrying end 2 thrusts medicine storing bag 1, and is incited somebody to action by microfluidic channel network 11
Medicament distribution is to loading end 3；Then the passage formed on skin by the microneedle array 17 of loading end 3 is flowed into human body and completes defeated
Medicine.
Although detailed description of the invention illustrative to this utility model is described above, in order to the art
Artisans understand that this utility model, it should be apparent that this utility model is not limited to the scope of detailed description of the invention, to this technology
From the point of view of the those of ordinary skill in field, if the essence of the present utility model that various change limits in appended claim and determines
In god and scope, these changes are apparent from, and all utility models utilizing this utility model to conceive are created all in protection
Row.
Claims (9)
1. the micropin dosing paster containing separate type medicine storing bag, it is characterised in that include an interchangeable drug storage of separate type
Capsule, integrates microneedle array and the medicine carrying end of microfluidic channel network, integrates microneedle array and microfluidic channel network for one for one
Loading end and the adhesive patches that micropin dosing paster can be attached on skin.
A kind of micropin dosing paster containing separate type medicine storing bag, it is characterised in that medicine storing bag comprises
One interface being connected with dosing paster medicine carrying end that is that formed by adhesive patches.
A kind of micropin dosing paster containing separate type medicine storing bag, it is characterised in that medicine carrying end comprises
The microneedle array of one group 5 × 5 and a microfluidic channel being incorporated in flexible base board, punctured medicine storing bag by microneedle array and touch
Send out loading.
A kind of micropin dosing paster containing separate type medicine storing bag, it is characterised in that loading end comprises
The microneedle array of one group 5 × 5 and a microfluidic channel being incorporated in flexible base board, punctured skin by microneedle array and complete
Loading.
A kind of micropin dosing paster containing separate type medicine storing bag, it is characterised in that paster entirety is tied
Structure is made up of flexible polymer, has the characteristic of flexibility, pro-skin.
A kind of micropin dosing paster containing separate type medicine storing bag, it is characterised in that the control of loading
Being to be completed by the joint motions of user, extruding and stretching that loading paster is produced by dependence arthrogryposis make medicine carrying end micropin
Array punctures medicine storing bag, starts the conveying of medicine.
A kind of micropin dosing paster containing separate type medicine storing bag, it is characterised in that described storage
Medicine bag is separate type, can be replaced according to the demand of conveying medicine.
8. a kind of micropin dosing paster containing separate type medicine storing bag as described in claim 1 or 3 or 4, it is characterised in that described
The microneedle array of medicine carrying end and loading end is internal containing being available for the passage that medicine circulates, and medicine can be by within microneedle array
Passage flows into microfluidic channel network and carries.
9. a kind of micropin dosing paster containing separate type medicine storing bag as described in claim 1 or 3 or 4, it is characterised in that described
Microneedle array is made up of SU-8 photoresist.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620619911.7U CN205814863U (en) | 2016-06-22 | 2016-06-22 | A kind of micropin dosing paster containing separate type medicine storing bag |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620619911.7U CN205814863U (en) | 2016-06-22 | 2016-06-22 | A kind of micropin dosing paster containing separate type medicine storing bag |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205814863U true CN205814863U (en) | 2016-12-21 |
Family
ID=58146574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620619911.7U Expired - Fee Related CN205814863U (en) | 2016-06-22 | 2016-06-22 | A kind of micropin dosing paster containing separate type medicine storing bag |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205814863U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963855A (en) * | 2016-06-22 | 2016-09-28 | 成都市亿泰科技有限公司 | Microneedle drug delivery patch containing separable drug capsule |
-
2016
- 2016-06-22 CN CN201620619911.7U patent/CN205814863U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963855A (en) * | 2016-06-22 | 2016-09-28 | 成都市亿泰科技有限公司 | Microneedle drug delivery patch containing separable drug capsule |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20161221 Termination date: 20210622 |