CN112294861A - Huo's muscle and bone plaster - Google Patents

Huo's muscle and bone plaster Download PDF

Info

Publication number
CN112294861A
CN112294861A CN202011411906.4A CN202011411906A CN112294861A CN 112294861 A CN112294861 A CN 112294861A CN 202011411906 A CN202011411906 A CN 202011411906A CN 112294861 A CN112294861 A CN 112294861A
Authority
CN
China
Prior art keywords
parts
muscle
mixing
silica gel
huo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202011411906.4A
Other languages
Chinese (zh)
Inventor
王鑫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202011411906.4A priority Critical patent/CN112294861A/en
Publication of CN112294861A publication Critical patent/CN112294861A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a Huoshan muscle and bone patch which comprises a medicine component and a substrate, wherein the medicine component comprises 8 parts of lycopodium clavatum, 200 parts of elm bark and 3-5 parts of cucumber seed by weight, and the substrate is formed by mixing 2-6 parts of micro silica gel, 6-12 parts of micro silica gel, 10-15 parts of calcium carbonate, 5-10 parts of glycerol, 2-5 parts of sodium alginate, 4-7 parts of gelatin and 0.5-1 part of titanium dioxide by weight. The invention can effectively eliminate the tendon and the edema, repair the tissue sclerosis, treat acute and chronic sprain and hydrops, dispel the wind and remove the dampness, promote blood circulation by removing blood stasis and relax the channels and collaterals. It can also be used for treating adhesion and repairing soft tissue degenerative diseases.

Description

Huo's muscle and bone plaster
Technical Field
The invention relates to the technical field of plasters, and particularly relates to a Huo's muscle and bone patch.
Background
The plaster on the market mostly has single drug effect, the drug effect is not obvious enough, and the requirement of multiple purposes of one plaster is not met.
An effective solution to the problems in the related art has not been proposed yet.
Disclosure of Invention
The invention aims to provide a Huo's muscle and bone patch to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: the Huoshan muscle and bone patch comprises medicine components and a matrix, wherein the medicine components comprise 8 parts of lycopodium clavatum, 200 parts of elm bark and 3-5 parts of cucumber seed by weight, and the matrix is formed by mixing 2-6 parts of the medicine components, 6-12 parts of micro silica gel, 10-15 parts of calcium carbonate, 5-10 parts of glycerol, 2-5 parts of sodium alginate, 4-7 parts of gelatin and 0.5-1 part of titanium dioxide by weight.
The preparation method of the Huo's muscle and bone patch comprises the following specific steps:
(1) removing impurities from herba Lycopodii and cortex Ulmi Pumilae, drying, pulverizing into coarse powder, sieving with 40 mesh sieve, drying semen Cucumidis Sativi, pulverizing into coarse powder, sieving with 120 mesh sieve, weighing above materials according to formula, soaking with 5-8 times of 40-60% ethanol for 2-4 times, 4 days each time, mixing soaking solutions, filtering, concentrating the filtrate to obtain extract with relative density of 1.15-1.20 at 60 deg.C, adding 60-80 mesh Borneolum Syntheticum, and mixing;
(2) mixing the micro silica gel powder, the calcium carbonate and the glycerol according to the formula ratio, adding the sodium alginate and the gelatin, and uniformly stirring;
(3) adding the traditional Chinese medicine extract prepared in the step (1) into the matrix prepared in the step (2), adding titanium dioxide, and stirring at the room temperature at the rotating speed of 50-70rpm/min for 30-50min to obtain an ointment;
(4) and (4) coating the medicine-containing ointment prepared in the step (3) on plaster paper, standing at room temperature for 18-24h, slicing and packaging.
Further, the rotating speed in the step (3) is 60rpm/min, the stirring time is 40min, and the standing time in the step (4) is 24 h.
Compared with the prior art, the invention has the following beneficial effects: the invention can effectively eliminate the tendon and the edema, repair the tissue sclerosis, treat acute and chronic sprain and hydrops, dispel the wind and remove the dampness, promote blood circulation by removing blood stasis and relax the channels and collaterals. Also can be used for treating adhesion and edema, and repairing soft tissue degenerative diseases.
Detailed Description
The invention will be further described with reference to specific embodiments:
the Huoshan muscle and bone patch comprises medicine components and a matrix, wherein the medicine components comprise 8 parts of lycopodium clavatum, 200 parts of elm bark and 3-5 parts of cucumber seeds, the matrix is formed by mixing 2-6 parts of medicine components, 6-12 parts of micro-powder silica gel, 10-15 parts of calcium carbonate, 5-10 parts of glycerol, 2-5 parts of sodium alginate, 4-7 parts of gelatin and 0.5-1 part of titanium dioxide, the cucumber seeds are used for treating fracture and muscle injuries and rheumatism arthralgia, the lycopodium clavatum dispels wind and removes dampness, the tendons and activate collaterals and the elm bark are used for treating edema and detumescence, and the lycopodium clavatum, the elm bark and cucumber seeds are used for treating fracture and muscle and bone injuries and rheumatism pain, The combination of the efficacies of elm bark and cucumber seed can effectively treat diseases such as tendon and tendon wrapping, edema, tissue sclerosis, acute sprain, tissue effusion, rheumatism and the like.
The preparation method of the Huo's muscle and bone patch comprises the following specific steps:
(1) removing impurities from herba Lycopodii and cortex Ulmi Pumilae, drying, pulverizing into coarse powder, sieving with 40 mesh sieve, drying semen Cucumidis Sativi, pulverizing into coarse powder, sieving with 120 mesh sieve, weighing above materials according to formula, soaking with 5-8 times of 40-60% ethanol for 2-4 times, 4 days each time, mixing soaking solutions, filtering, concentrating the filtrate to obtain extract with relative density of 1.15-1.20 at 60 deg.C, adding 60-80 mesh Borneolum Syntheticum, and mixing;
(2) mixing the micro silica gel powder, the calcium carbonate and the glycerol according to the formula ratio, adding the sodium alginate and the gelatin, and uniformly stirring;
(3) adding the traditional Chinese medicine extract prepared in the step (1) into the matrix prepared in the step (2), adding titanium dioxide, and stirring at the room temperature at the rotating speed of 50-70rpm/min for 30-50min to obtain an ointment;
(4) and (4) coating the medicine-containing ointment prepared in the step (3) on plaster paper, standing at room temperature for 18-24h, slicing and packaging.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art will understand that various changes, modifications and substitutions can be made without departing from the spirit and scope of the invention as defined by the appended claims. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (3)

1. The Huoshan muscle and bone patch is characterized by comprising medicine components and a matrix, wherein the medicine components comprise 8 parts of lycopodium clavatum, 200 parts of elm bark and 3-5 parts of cucumber seeds, and the matrix is formed by mixing 2-6 parts of the medicine components, 6-12 parts of superfine silica gel powder, 10-15 parts of calcium carbonate, 5-10 parts of glycerol, 2-5 parts of sodium alginate, 4-7 parts of gelatin and 0.5-1 part of titanium dioxide.
2. The preparation method of the Huo's muscle and bone patch as claimed in claim 1 comprises the following steps:
(1) removing impurities from herba Lycopodii and cortex Ulmi Pumilae, drying, pulverizing into coarse powder, sieving with 40 mesh sieve, drying semen Cucumidis Sativi, pulverizing into coarse powder, sieving with 120 mesh sieve, weighing above materials according to formula, soaking with 5-8 times of 40-60% ethanol for 2-4 times, 4 days each time, mixing soaking solutions, filtering, concentrating the filtrate to obtain extract with relative density of 1.15-1.20 at 60 deg.C, adding 60-80 mesh Borneolum Syntheticum, and mixing;
(2) mixing the micro silica gel powder, the calcium carbonate and the glycerol according to the formula ratio, adding the sodium alginate and the gelatin, and uniformly stirring;
(3) adding the traditional Chinese medicine extract prepared in the step (1) into the matrix prepared in the step (2), adding titanium dioxide, and stirring at the room temperature at the rotating speed of 50-70rpm/min for 30-50min to obtain an ointment;
(4) and (4) coating the medicine-containing ointment prepared in the step (3) on plaster paper, standing at room temperature for 18-24h, slicing and packaging.
3. The method for preparing Huo's muscle and bone paste as claimed in claim 2, wherein the rotation speed in step (3) is 60rpm/min, the stirring time is 40min, and the standing time in step (4) is 24 h.
CN202011411906.4A 2020-12-04 2020-12-04 Huo's muscle and bone plaster Withdrawn CN112294861A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011411906.4A CN112294861A (en) 2020-12-04 2020-12-04 Huo's muscle and bone plaster

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011411906.4A CN112294861A (en) 2020-12-04 2020-12-04 Huo's muscle and bone plaster

Publications (1)

Publication Number Publication Date
CN112294861A true CN112294861A (en) 2021-02-02

Family

ID=74487350

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011411906.4A Withdrawn CN112294861A (en) 2020-12-04 2020-12-04 Huo's muscle and bone plaster

Country Status (1)

Country Link
CN (1) CN112294861A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115139583A (en) * 2022-01-13 2022-10-04 杭州聚奎科技有限公司 Preparation method of anti-slip ground mat
CN115671159A (en) * 2021-12-24 2023-02-03 王鑫 Muscle and bone plaster

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115671159A (en) * 2021-12-24 2023-02-03 王鑫 Muscle and bone plaster
CN115139583A (en) * 2022-01-13 2022-10-04 杭州聚奎科技有限公司 Preparation method of anti-slip ground mat
CN115139583B (en) * 2022-01-13 2024-01-09 杭州聚奎科技有限公司 Preparation method of anti-skid floor mat

Similar Documents

Publication Publication Date Title
CN112294861A (en) Huo's muscle and bone plaster
CN1147311C (en) External-use medicine for treating sore ulcer, wound, rheumatism and other diseases and its preparation
CN115671159A (en) Muscle and bone plaster
CN104887958B (en) Treat Chinese medicine preparation of Shelled Turtle Trionyx Sinensis enteritis and preparation method thereof
CN108126078A (en) A kind of plaster
CN108578588A (en) A kind of arthralgia and myalgia patch and its manufacturing method
CN1196491C (en) Ointment for healing tranumatic injury fast
CN108671121A (en) A kind of massage cream and preparation method thereof for treating arthralgia and myalgia
CN107550974A (en) Externally-applied medicinal composition of facial paralysis and application thereof
CN105251044A (en) Polyglycolic acid anti-infection surgical suture and preparation method
CN102198196A (en) External washing agent for treating dermatophytosis
CN110731992A (en) paralysis plaster, its preparation method and paralysis plaster prepared thereby
CN103860828A (en) Medicament for treating traumatic injuries and fracture and preparation method thereof
CN1062175C (en) Medicated wine and preparing method thereof
CN108403965A (en) A kind of plaster for treating empyrosis
CN106266289A (en) A kind of external Chinese medicament for treating fracture, sprain
CN114681552B (en) Musk pain-relieving cataplasm and preparation method thereof
CN1054772C (en) Quick-acting Duangusan powder capable of setting of fracture in 2-6 hours
CN114832027A (en) External washing traditional Chinese medicine capable of helping fracture postoperative patient with limited joint movement
CN105663951A (en) External strong medicine composition for treating traumatic injuries and preparation method thereof
CN101468120A (en) Plaster for burn and method for preparing the same
CN108478690A (en) A kind of dispelling wind and eliminating dampness, active pain relieving external medicine preparation and preparation method thereof
CN104825559B (en) A kind of drug gel patch for treating acute soft tissue injury and preparation method thereof
CN114601873A (en) Itching relieving patch prepared from spearmint and preparation method thereof
CN103933362B (en) External-use medicament for improving sexual function

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20210202

WW01 Invention patent application withdrawn after publication