CN112274442A - Children toothpaste containing calcium gluconate and preparation method thereof - Google Patents
Children toothpaste containing calcium gluconate and preparation method thereof Download PDFInfo
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- CN112274442A CN112274442A CN202011002586.7A CN202011002586A CN112274442A CN 112274442 A CN112274442 A CN 112274442A CN 202011002586 A CN202011002586 A CN 202011002586A CN 112274442 A CN112274442 A CN 112274442A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- Alternative & Traditional Medicine (AREA)
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Abstract
The invention discloses a children toothpaste containing calcium gluconate and a preparation method thereof, wherein the children toothpaste comprises the following preparation raw materials in percentage by weight: 40 to 50 percent of calcium gluconate, 8 to 12 percent of glycerol, 15 to 25 percent of xylitol, 0.5 to 1 percent of binder, 0.11 to 0.2 percent of foaming agent, 1 to 2 percent of spice, 0.05 to 0.5 percent of preservative, 0.05 to 0.5 percent of saccharin, 0.5 to 1 percent of corrosion inhibitor, 1 to 2 percent of radix bupleuri and 20 to 30 percent of deionized water. The calcium gluconate is used as the friction agent, is a food-grade calcium enhancer and has no irritation, so that the respiratory tract is not stimulated, the growth of teeth can be promoted, and the teeth can be protected; the radix bupleuri is added, so that cold can be prevented, the cold frequency is reduced, and the traditional Chinese medicine composition also has a treatment effect on rhinitis and headache, so that a certain prevention effect is achieved.
Description
Technical Field
The invention relates to the technical field of toothpaste preparation, in particular to children toothpaste containing calcium gluconate and a preparation method thereof.
Background
The toothpaste is a cleaning article commonly used in daily life, is a dentifrice, is generally in a gel shape, can be usually smeared on a toothbrush for cleaning teeth, keeps the beauty and brightness of the teeth, has a long history, and with the continuous development of scientific technology, the continuous improvement and perfection of manufacturing technology and equipment, various types of toothpaste are appeared one after another, the quality and the grade of products are continuously improved, and as far as 2019, the variety of the toothpaste is changed from single cleaning type toothpaste, the toothpaste is developed into hundreds of multifunctional toothpastes with complete varieties and various functions, thereby meeting the requirements of different consumption levels.
The existing toothpaste uses calcium pyrophosphate as an abrasive, but calcium pyrophosphate has irritation, so that a certain influence is easily caused on respiratory tract, the existing children frequently suffer from cold, children cannot use heavier medicines when suffering from cold, and need to be treated by Chinese patent medicines for a long time, so that great pain is caused to the children, and the existing toothpaste does not have the function of preventing cold, so that the toothpaste for children containing calcium gluconate and the preparation method thereof are provided.
Disclosure of Invention
The invention aims to provide a children toothpaste containing calcium gluconate and a preparation method thereof, which solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: the children toothpaste containing calcium gluconate comprises the following preparation raw materials in percentage by weight: 40 to 50 percent of calcium gluconate, 8 to 12 percent of glycerol, 15 to 25 percent of xylitol, 0.5 to 1 percent of binder, 0.11 to 0.2 percent of foaming agent, 1 to 2 percent of spice, 0.05 to 0.5 percent of preservative, 0.05 to 0.5 percent of saccharin, 0.5 to 1 percent of corrosion inhibitor, 1 to 2 percent of radix bupleuri and 20 to 30 percent of deionized water.
As a preferred embodiment of the present invention, the preservative is sodium benzoate.
As a preferred embodiment of the present invention, the corrosion inhibitor is silica.
As a preferred embodiment of the present invention, the flavor is peppermint oil.
As a preferred embodiment of the present invention, the binder is carboxymethyl cellulose.
As a preferred embodiment of the present invention, the foaming agent is sodium lauryl sulfate.
As a preferred embodiment of the present invention, the preparation steps of the children toothpaste containing calcium gluconate are as follows:
step one, preparing glue, namely sucking xylitol into a glue preparing pot, adding a binder to dissolve the xylitol, stirring the xylitol at a high speed by stirring equipment, adding deionized water, calcium gluconate, glycerol, spice, saccharin, a preservative, a corrosion inhibitor and radix bupleuri to stir the xylitol uniformly, and standing the xylitol for a period of time after stirring the xylitol uniformly;
step two, kneading: putting the mixture obtained in the step one into a kneader for kneading, and vacuumizing by using vacuum equipment;
step three, grinding: grinding the kneaded paste by using grinding equipment, further refining under the action of mechanical shear force to homogenize various particles in the paste, and vacuumizing while grinding;
step four, aging: putting the paste prepared in the step three into a storage pot for aging, and naturally cooling to normal temperature;
step five, filling: and (5) performing filling classification by using filling equipment.
In a preferred embodiment of the present invention, the degree of vacuum is-0.096 MPa.
Compared with the prior art, the invention has the following beneficial effects:
the invention uses the calcium gluconate as an abrasive, and the calcium gluconate is a food-grade calcium enhancer and has no irritation, so that the respiratory tract is not stimulated, the growth of teeth can be promoted, and the teeth can be protected.
The invention can prevent cold and reduce the number of cold by adding the radix bupleuri, and has treatment effect on rhinitis and headache, thereby playing a certain role in prevention.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
The invention provides a technical scheme that: the children toothpaste containing calcium gluconate comprises the following preparation raw materials in percentage by weight: 40-50% of calcium gluconate, 8-12% of glycerol, 15-25% of xylitol, 0.5-1% of binder, 0.11-0.2% of foaming agent, 1-2% of spice, 0.05-0.5% of preservative, 0.05-0.5% of saccharin, 0.5-1% of corrosion inhibitor, 1-2% of radix bupleuri and 20-30% of deionized water, wherein the preservative is sodium benzoate, the corrosion inhibitor is silicon dioxide, the spice is peppermint oil, the binder is carboxymethyl cellulose, and the foaming agent is sodium lauryl sulfate.
Example one
The preparation method of the children toothpaste containing calcium gluconate comprises the following steps:
the method comprises the following steps: preparing glue, namely sucking 20 percent of xylitol into a glue preparing pot, adding 0.5 percent of carboxymethyl cellulose for dissolving, stirring at a high speed by using stirring equipment, adding 25 percent of deionized water, 45 percent of calcium gluconate, 10 percent of glycerol, 1 percent of spice, 0.05 percent of saccharin, 0.05 percent of sodium benzoate, 0.5 percent of silicon dioxide and 1 percent of radix bupleuri, stirring uniformly, and standing for a period of time after stirring uniformly;
step two, kneading: putting the mixture obtained in the step one into a kneader for kneading, and simultaneously vacuumizing by using vacuum equipment, wherein the vacuum degree is-0.096 Mpa;
step three, grinding: grinding the kneaded paste by using grinding equipment, further refining under the action of mechanical shear force to homogenize various particles in the paste, and vacuumizing while grinding, wherein the vacuum degree is-0.096 Mpa;
step four, aging: putting the paste prepared in the step three into a storage pot for aging, and naturally cooling to normal temperature;
step five, filling: and (5) performing filling classification by using filling equipment.
Example two
The preparation method of the children toothpaste containing calcium gluconate comprises the following steps:
the method comprises the following steps: preparing glue, namely sucking 20 percent of xylitol into a glue preparing pot, adding 0.5 percent of carboxymethyl cellulose for dissolving, stirring at a high speed by using stirring equipment, adding 25 percent of deionized water, 45 percent of calcium gluconate, 10 percent of glycerol, 1 percent of spice, 0.05 percent of saccharin, 0.05 percent of sodium benzoate, 0.5 percent of silicon dioxide and 2 percent of radix bupleuri, stirring uniformly, and standing for a period of time after stirring uniformly;
step two, kneading: putting the mixture obtained in the step one into a kneader for kneading, and simultaneously vacuumizing by using vacuum equipment, wherein the vacuum degree is-0.096 Mpa;
step three, grinding: grinding the kneaded paste by using grinding equipment, further refining under the action of mechanical shear force to homogenize various particles in the paste, and vacuumizing while grinding, wherein the vacuum degree is-0.096 Mpa;
step four, aging: putting the paste prepared in the step three into a storage pot for aging, and naturally cooling to normal temperature;
step five, filling: and (5) performing filling classification by using filling equipment.
EXAMPLE III
The preparation method of the children toothpaste containing calcium gluconate comprises the following steps:
the method comprises the following steps: preparing glue, namely sucking 20 percent of xylitol into a glue preparing pot, adding 0.5 percent of carboxymethyl cellulose for dissolving, stirring at a high speed by using stirring equipment, adding 25 percent of deionized water, 50 percent of calcium gluconate, 10 percent of glycerol, 1 percent of spice, 0.05 percent of saccharin, 0.05 percent of sodium benzoate, 0.5 percent of silicon dioxide and 1 percent of radix bupleuri, stirring uniformly, and standing for a period of time after stirring uniformly;
step two, kneading: putting the mixture obtained in the step one into a kneader for kneading, and simultaneously vacuumizing by using vacuum equipment, wherein the vacuum degree is-0.096 Mpa;
step three, grinding: grinding the kneaded paste by using grinding equipment, further refining under the action of mechanical shear force to homogenize various particles in the paste, and vacuumizing while grinding, wherein the vacuum degree is-0.096 Mpa;
step four, aging: putting the paste prepared in the step three into a storage pot for aging, and naturally cooling to normal temperature;
step five, filling: and (5) performing filling classification by using filling equipment.
EXAMPLE III
The preparation method of the children toothpaste containing calcium gluconate comprises the following steps:
the method comprises the following steps: preparing glue, namely sucking 20 percent of xylitol into a glue preparing pot, adding 0.5 percent of carboxymethyl cellulose for dissolving, stirring at a high speed by using stirring equipment, adding 25 percent of deionized water, 50 percent of calcium gluconate, 10 percent of glycerol, 1 percent of spice, 0.05 percent of saccharin, 0.05 percent of sodium benzoate, 0.5 percent of silicon dioxide and 2 percent of radix bupleuri, stirring uniformly, and standing for a period of time after stirring uniformly;
step two, kneading: putting the mixture obtained in the step one into a kneader for kneading, and simultaneously vacuumizing by using vacuum equipment, wherein the vacuum degree is-0.096 Mpa;
step three, grinding: grinding the kneaded paste by using grinding equipment, further refining under the action of mechanical shear force to homogenize various particles in the paste, and vacuumizing while grinding, wherein the vacuum degree is-0.096 Mpa;
step four, aging: putting the paste prepared in the step three into a storage pot for aging, and naturally cooling to normal temperature;
step five, filling: and (5) performing filling classification by using filling equipment.
In summary, according to the experimental data comparison, the first embodiment is the best embodiment, the calcium gluconate is used as the friction agent, is a food-grade calcium enhancer and is nonirritating, so that the respiratory tract is not stimulated, the growth of teeth can be promoted, and the teeth can be protected; the radix bupleuri is added, so that cold can be prevented, the cold frequency is reduced, and the traditional Chinese medicine composition also has a treatment effect on rhinitis and headache, so that a certain prevention effect is achieved.
While there have been shown and described what are at present considered the fundamental principles and essential features of the invention and its advantages, it will be apparent to those skilled in the art that the invention is not limited to the details of the foregoing exemplary embodiments, but is capable of other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (8)
1. The children toothpaste containing calcium gluconate is characterized in that: the preparation method comprises the following raw materials in percentage by weight: 40 to 50 percent of calcium gluconate, 8 to 12 percent of glycerol, 15 to 25 percent of xylitol, 0.5 to 1 percent of binder, 0.11 to 0.2 percent of foaming agent, 1 to 2 percent of spice, 0.05 to 0.5 percent of preservative, 0.05 to 0.5 percent of saccharin, 0.5 to 1 percent of corrosion inhibitor, 1 to 2 percent of radix bupleuri and 20 to 30 percent of deionized water.
2. The calcium gluconate-containing children's toothpaste according to claim 1, wherein: the preservative is sodium benzoate.
3. The calcium gluconate-containing children's toothpaste according to claim 1, wherein: the corrosion inhibitor is silicon dioxide.
4. The calcium gluconate-containing children's toothpaste according to claim 1, wherein: the spice is peppermint oil.
5. The calcium gluconate-containing children's toothpaste according to claim 1, wherein: the binder is carboxymethyl cellulose.
6. The calcium gluconate-containing children's toothpaste according to claim 1, wherein: the foaming agent is sodium lauryl sulfate.
7. The preparation method of the children toothpaste containing calcium gluconate is characterized in that the children toothpaste containing calcium gluconate of any one of claims 1 to 6 is used, and the treatment method of the children toothpaste containing calcium gluconate comprises the following steps:
step one, preparing glue, namely sucking xylitol into a glue preparing pot, adding a binder to dissolve the xylitol, stirring the xylitol at a high speed by stirring equipment, adding deionized water, calcium gluconate, glycerol, spice, saccharin, a preservative, a corrosion inhibitor and radix bupleuri to stir the xylitol uniformly, and standing the xylitol for a period of time after stirring the xylitol uniformly;
step two, kneading: putting the mixture obtained in the step one into a kneader for kneading, and vacuumizing by using vacuum equipment;
step three, grinding: grinding the kneaded paste by using grinding equipment, further refining under the action of mechanical shear force to homogenize various particles in the paste, and vacuumizing while grinding;
step four, aging: putting the paste prepared in the step three into a storage pot for aging, and naturally cooling to normal temperature;
step five, filling: and (5) performing filling classification by using filling equipment.
8. The children toothpaste containing calcium gluconate according to claim 7, wherein the toothpaste comprises: the vacuum degree is-0.096 Mpa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011002586.7A CN112274442A (en) | 2020-09-22 | 2020-09-22 | Children toothpaste containing calcium gluconate and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011002586.7A CN112274442A (en) | 2020-09-22 | 2020-09-22 | Children toothpaste containing calcium gluconate and preparation method thereof |
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| CN112274442A true CN112274442A (en) | 2021-01-29 |
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| CN202011002586.7A Pending CN112274442A (en) | 2020-09-22 | 2020-09-22 | Children toothpaste containing calcium gluconate and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113197794A (en) * | 2021-05-10 | 2021-08-03 | 广州市盛龙口腔清洁用品有限公司 | Children toothpaste for preventing decayed teeth and preparation method thereof |
Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85106306A (en) * | 1985-08-16 | 1986-05-10 | 高光周 | Prevent the toothpaste additive of dental caries |
| CN1153632A (en) * | 1996-01-02 | 1997-07-09 | 李国华 | Calcium replenishing toothpaste |
| CN101152134A (en) * | 2007-10-12 | 2008-04-02 | 汪英俊 | Health care toothpaste |
| CN101692997A (en) * | 2009-09-30 | 2010-04-14 | 广东名臣有限公司 | Toothpaste containing trace active mineral substances |
| CN103315918A (en) * | 2012-03-22 | 2013-09-25 | 王祉童 | Mothproof toothpaste additive |
| CN103816271A (en) * | 2014-03-18 | 2014-05-28 | 无限极（中国）有限公司 | Traditional Chinese medicine extract, preparation method thereof and raw material composition and toothpaste thereof |
| CN104224627A (en) * | 2014-09-18 | 2014-12-24 | 安徽科技学院 | Heat-clearing, detoxifying and health-care toothpaste and production method thereof |
| CN104306190A (en) * | 2014-09-19 | 2015-01-28 | 拉芳家化股份有限公司 | Composition for prevention and treatment of oral ulcer |
| CN104837469A (en) * | 2012-10-12 | 2015-08-12 | 荷兰联合利华有限公司 | Oral care composition |
| CN105534867A (en) * | 2016-01-25 | 2016-05-04 | 王嫣俐 | Edible child health care toothpaste and preparation method thereof |
| CN105902409A (en) * | 2016-05-13 | 2016-08-31 | 广东龙湖科技股份有限公司 | Toothpaste with good mild thixotropy and preparation method of toothpaste |
| CN108125885A (en) * | 2016-12-01 | 2018-06-08 | 青岛赛泽网络科技有限公司 | A kind of gum health toothpaste |
| CN108125838A (en) * | 2016-12-01 | 2018-06-08 | 青岛赛泽网络科技有限公司 | A kind of Chinese medicine inflammation-diminishing toothpaste |
-
2020
- 2020-09-22 CN CN202011002586.7A patent/CN112274442A/en active Pending
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85106306A (en) * | 1985-08-16 | 1986-05-10 | 高光周 | Prevent the toothpaste additive of dental caries |
| CN1153632A (en) * | 1996-01-02 | 1997-07-09 | 李国华 | Calcium replenishing toothpaste |
| CN101152134A (en) * | 2007-10-12 | 2008-04-02 | 汪英俊 | Health care toothpaste |
| CN101692997A (en) * | 2009-09-30 | 2010-04-14 | 广东名臣有限公司 | Toothpaste containing trace active mineral substances |
| CN103315918A (en) * | 2012-03-22 | 2013-09-25 | 王祉童 | Mothproof toothpaste additive |
| CN104837469A (en) * | 2012-10-12 | 2015-08-12 | 荷兰联合利华有限公司 | Oral care composition |
| CN103816271A (en) * | 2014-03-18 | 2014-05-28 | 无限极（中国）有限公司 | Traditional Chinese medicine extract, preparation method thereof and raw material composition and toothpaste thereof |
| CN104224627A (en) * | 2014-09-18 | 2014-12-24 | 安徽科技学院 | Heat-clearing, detoxifying and health-care toothpaste and production method thereof |
| CN104306190A (en) * | 2014-09-19 | 2015-01-28 | 拉芳家化股份有限公司 | Composition for prevention and treatment of oral ulcer |
| CN105534867A (en) * | 2016-01-25 | 2016-05-04 | 王嫣俐 | Edible child health care toothpaste and preparation method thereof |
| CN105902409A (en) * | 2016-05-13 | 2016-08-31 | 广东龙湖科技股份有限公司 | Toothpaste with good mild thixotropy and preparation method of toothpaste |
| CN108125885A (en) * | 2016-12-01 | 2018-06-08 | 青岛赛泽网络科技有限公司 | A kind of gum health toothpaste |
| CN108125838A (en) * | 2016-12-01 | 2018-06-08 | 青岛赛泽网络科技有限公司 | A kind of Chinese medicine inflammation-diminishing toothpaste |
Non-Patent Citations (2)
| Title |
|---|
| 何致武 等: "《家庭购物百事通》", 31 March 1991 * |
| 张国干 等: "《工业化学》", 31 October 1998 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113197794A (en) * | 2021-05-10 | 2021-08-03 | 广州市盛龙口腔清洁用品有限公司 | Children toothpaste for preventing decayed teeth and preparation method thereof |
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