CN112190615A - Traditional Chinese medicine formula for treating type II diabetes - Google Patents
Traditional Chinese medicine formula for treating type II diabetes Download PDFInfo
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- CN112190615A CN112190615A CN201910609820.3A CN201910609820A CN112190615A CN 112190615 A CN112190615 A CN 112190615A CN 201910609820 A CN201910609820 A CN 201910609820A CN 112190615 A CN112190615 A CN 112190615A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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Abstract
The invention discloses a traditional Chinese medicine formula for treating type II diabetes, which belongs to the field of diabetes treatment and comprises the following medicinal materials in parts by mass: 16-20mg of natural astaxanthin, 0.8-1g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.2-3.25g of cinnamon extract, wherein the pure traditional Chinese medicine coptis extract is berberine, the bitter gourd extract is momordin, the cinnamon extract is cinnamyl polyphenol and cinnamyl aldehyde, the cinnamyl polyphenol is 200-250mg, and the cinnamyl aldehyde is 3 g. Under the guidance of the traditional Chinese medicine theory and clinical experience, the raw materials and the proportion thereof are selected precisely, and the synergistic or resistance effect of the raw materials is utilized to improve the curative effect.
Description
Technical Field
The invention relates to the technical field of diabetes treatment, in particular to a traditional Chinese medicine formula for treating type II diabetes.
Background
The type II diabetes, the primary name of which is adult onset diabetes, mostly occurs after the age of 35-40 years, accounts for more than 90% of diabetics, is an endocrine metabolic disease and has genetic susceptibility, and the main pathogenesis relates to pancreatic beta cell dysfunction (incapable of secreting sufficient insulin), peripheral insulin resistance and the like.
At present, in clinical treatment medicines aiming at the pathogenesis of type II diabetes, metformin and glitazone which can improve insulin resistance comprise insulin secretagogues, sulfonylureas and meglitinides, alpha glucosidase inhibitors which can inhibit the glucose absorption of gastrointestinal tracts, and incretin hypoglycemic medicines such as glucagon-like polypeptide 1 analogues or receptor agonists thereof, DDP-IV inhibitors and insulin.
Disclosure of Invention
Technical problem to be solved
1. Technical problem to be solved
Aiming at the problems in the prior art, the invention aims to provide a traditional Chinese medicine formula for treating type II diabetes, which has the advantages of improving the curative effect of the medicine and reducing side effects, and solves the problems that western medicines have certain effects on the treatment of type II diabetes, but have the defects of large side effects, slow effect and unstable curative effect.
(II) technical scheme
In order to achieve the purposes of improving the curative effect of the medicine and reducing side effects, the invention provides the following technical scheme: a traditional Chinese medicine formula for treating type II diabetes comprises the following medicinal materials in parts by mass: 16-20mg of natural astaxanthin, 0.8-1g of pure traditional Chinese medicine coptis extract, 4g of balsam pear extract and 3.2-3.25g of cinnamon extract.
Preferably, the pure traditional Chinese medicine coptis extract is berberine, and the balsam pear extract is momordicin.
Preferably, the cinnamon extract is cinnamyl polyphenol and cinnamaldehyde, the cinnamyl polyphenol is 200-250mg, and the cinnamaldehyde is 3 g.
Preferably, the traditional Chinese medicine composition comprises the following medicinal materials in parts by mass: 16mg of natural astaxanthin, 0.8g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.2g of cinnamon extract.
Preferably, the traditional Chinese medicine composition comprises the following medicinal materials in parts by mass: 18mg of natural astaxanthin, 0.9g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.225g of cinnamon extract.
Preferably, the traditional Chinese medicine composition comprises the following medicinal materials in parts by mass: 20mg of natural astaxanthin, 1g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.25g of cinnamon extract.
Preferably, the traditional Chinese medicine composition can be prepared into a medicament or a pill for taking according to the traditional Chinese medicine formula.
(III) advantageous effects
Compared with the prior art, the invention provides a traditional Chinese medicine formula for treating type II diabetes, which has the following beneficial effects:
1. according to the traditional Chinese medicine formula for treating type II diabetes, under the guidance of the traditional Chinese medicine theory and clinical experience, various raw material medicines and the proportion thereof are selected, and the synergistic or resistant effect of the raw material medicines is utilized, so that the curative effect is improved, and the traditional Chinese medicine formula has the advantages of remarkable curative effect, small side effect, simplicity in preparation and low cost, and has a wide market prospect.
2. Experiments prove that the traditional Chinese medicine formula has the effective rate of over 95 percent and has obvious effect compared with certain commercially available western medicines.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
a traditional Chinese medicine formula for treating type II diabetes comprises the following medicinal materials in parts by mass: 16mg of natural astaxanthin, 0.8g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.2g of cinnamon extract.
Furthermore, the pure traditional Chinese medicine coptis extract is berberine, and the balsam pear extract is momordicin.
Further, the cinnamon extract comprises cinnamyl polyphenol and cinnamaldehyde, wherein the cinnamon polyphenol is 200mg, and the cinnamaldehyde is 3 g.
Furthermore, the traditional Chinese medicine composition can be prepared into a medicament or a pill for taking according to a traditional Chinese medicine formula.
Example two:
a traditional Chinese medicine formula for treating type II diabetes comprises the following medicinal materials in parts by mass: 18mg of natural astaxanthin, 0.9g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.225g of cinnamon extract.
Furthermore, the pure traditional Chinese medicine coptis extract is berberine, and the balsam pear extract is momordicin.
Further, the cinnamon extract comprises cinnamon polyphenol and cinnamaldehyde, wherein the cinnamon polyphenol is 225mg, and the cinnamaldehyde is 3 g.
Furthermore, the traditional Chinese medicine composition can be prepared into a medicament or a pill for taking according to a traditional Chinese medicine formula.
Example three:
a traditional Chinese medicine formula for treating type II diabetes comprises the following medicinal materials in parts by mass: 20mg of natural astaxanthin, 1g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.25g of cinnamon extract.
Furthermore, the pure traditional Chinese medicine coptis extract is berberine, and the balsam pear extract is momordicin.
Further, the cinnamon extract comprises cinnamaldehyde and cinnamaldehyde, wherein the cinnamaldehyde is 3g, and the cinnamaldehyde is 250 mg.
Furthermore, the traditional Chinese medicine composition can be prepared into a medicament or a pill for taking according to a traditional Chinese medicine formula.
The curative effect of the traditional Chinese medicine is as follows:
natural astaxanthin: the natural astaxanthin has strong antioxidant capacity, is much stronger than that of other antioxidants, delays and improves aging caused by oxidation, can eliminate oxygen radicals, which is the main cause of cardiovascular diseases, effectively eliminates the free radicals to prevent the cardiovascular diseases, has good effect on diabetic nephropathy, especially has the effect of delaying and improving diabetic complications, and has the effect of enhancing immunity.
The coptis chinensis extract: clearing heat, eliminating dampness, purging pathogenic fire, removing toxic substances, and can be used for treating damp-heat, abdominal fullness, emesis, acid regurgitation, dysentery, jaundice, hyperpyrexia, coma, excessive heart fire, vexation, insomnia, hematemesis, epistaxis, conjunctival congestion, toothache, diabetes, carbuncle, swelling, and sore; it is used externally to treat eczema, eczema and purulent ear canal.
The bitter gourd extract: the extract of balsam pear has good hypoglycemic effect, called as plant insulin, and compared with western hypoglycemic drugs, the extract has no toxic or side effect, the balsam pear contains steroidal saponins such as charantin, insulin-like peptides and alkaloids, the substances endow the balsam pear with hypoglycemic activity, and the charantin stimulates the release of insulin and hinders the formation of glucose in blood stream, and the function can play a great role in the treatment of diabetes, particularly non-insulin dependent diabetes mellitus.
Cinnamon extract: the traditional Chinese medicine composition has the effects of tonifying fire and supporting yang, guiding fire to the source, dispelling cold and relieving pain, activating blood and stimulating the menstrual flow, and has obvious enhancement effect on the immune function of a human body.
Experimental example: selecting 60 patients, 10 patients in one group, and taking each patient with an empty stomach in the morning and evening for four weeks;
randomly extracting 60 patients, and randomly dividing into two groups of 30 patients, wherein each person in the treatment group is taken in the morning and at night on an empty stomach for four weeks, and the control group is taken in a certain commercial western medicine for four weeks, wherein the treatment group comprises 14 male patients and 16 female patients, and the age is between 44 and 76 years old; control group 13 male patients and 17 female patients aged 43-72 years, the results are given in the following table.
The curative effect standard is as follows: and (4) invalidation: symptoms are not alleviated, and blood glucose is not reduced; secondly, the method is effective: dry mouth, remission of polyuria symptoms and reduction of blood sugar; ③ showing effect: blood glucose is in the normal range; and (6) displaying the result.
The results are given in the following table:
after 24 effective persons in the treatment group and 15 effective persons in the control group stop taking the medicine for two weeks, the two effective persons are checked again for effect, if the normal blood sugar is maintained to be completely effective, if the diabetic symptoms are recovered again, the effect is judged to be effective, the result shows that the blood sugar of 24 persons in the treatment group is normal, 10 persons in the control group is completely stable, the blood sugar value of 5 persons is increased, and the diabetic symptoms appear.
Therefore, the effective rate of the traditional Chinese medicine formula for treating the type II diabetes mellitus in the scheme is up to more than 95%, and the traditional Chinese medicine formula has an obvious effect compared with certain commercially available western medicine.
The invention has the beneficial effects that: according to the traditional Chinese medicine formula for treating type II diabetes, under the guidance of the traditional Chinese medicine theory and clinical experience, various raw material medicines and the proportion thereof are selected, and the synergistic or resistant effect of the raw material medicines is utilized, so that the curative effect is improved, and the traditional Chinese medicine formula has the advantages of remarkable curative effect, small side effect, simplicity in preparation and low cost, and has a wide market prospect.
The foregoing is only a preferred embodiment of the present invention; the scope of the invention is not limited thereto. Any person skilled in the art should be able to cover the technical scope of the present invention by equivalent or modified solutions and modifications within the technical scope of the present invention.
Claims (7)
1. A traditional Chinese medicine formula for treating type II diabetes comprises the following medicinal materials in parts by mass: 16-20mg of natural astaxanthin, 0.8-1g of pure traditional Chinese medicine coptis extract, 4g of balsam pear extract and 3.2-3.25g of cinnamon extract.
2. The traditional Chinese medicine formula for treating type II diabetes mellitus according to claim 1, is characterized in that: the pure traditional Chinese medicine coptis extract is berberine, and the balsam pear extract is momordicin.
3. The traditional Chinese medicine formula for treating type II diabetes mellitus according to claim 1, is characterized in that: the cinnamon extract comprises 200-250mg of cinnamyl polyphenol and 3g of cinnamyl aldehyde.
4. The traditional Chinese medicine formula for treating type II diabetes mellitus according to claim 1, is characterized in that: comprises the following medicinal materials in percentage by mass: 16mg of natural astaxanthin, 0.8g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.2g of cinnamon extract.
5. The traditional Chinese medicine formula for treating type II diabetes mellitus according to claim 1, is characterized in that: comprises the following medicinal materials in percentage by mass: 18mg of natural astaxanthin, 0.9g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.225g of cinnamon extract.
6. The traditional Chinese medicine formula for treating type II diabetes mellitus according to claim 1, is characterized in that: comprises the following medicinal materials in percentage by mass: 20mg of natural astaxanthin, 1g of pure traditional Chinese medicine coptis extract, 4g of bitter gourd extract and 3.25g of cinnamon extract.
7. The traditional Chinese medicine formula for treating type II diabetes mellitus according to any one of claims 1 to 6, which is characterized in that: the traditional Chinese medicine composition can be prepared into a medicament or a pill for taking according to the traditional Chinese medicine formula.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910609820.3A CN112190615A (en) | 2019-07-08 | 2019-07-08 | Traditional Chinese medicine formula for treating type II diabetes |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910609820.3A CN112190615A (en) | 2019-07-08 | 2019-07-08 | Traditional Chinese medicine formula for treating type II diabetes |
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| CN112190615A true CN112190615A (en) | 2021-01-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201910609820.3A Pending CN112190615A (en) | 2019-07-08 | 2019-07-08 | Traditional Chinese medicine formula for treating type II diabetes |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085079A (en) * | 2007-07-06 | 2007-12-12 | 陈奇 | Traditional Chinese medicine compound for treating diabetes and its preparation method and application |
| CN103720803A (en) * | 2014-01-25 | 2014-04-16 | 苏州法莫生物技术有限公司 | Medicine for treating yang-deficiency diabetes mellitus |
-
2019
- 2019-07-08 CN CN201910609820.3A patent/CN112190615A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085079A (en) * | 2007-07-06 | 2007-12-12 | 陈奇 | Traditional Chinese medicine compound for treating diabetes and its preparation method and application |
| CN103720803A (en) * | 2014-01-25 | 2014-04-16 | 苏州法莫生物技术有限公司 | Medicine for treating yang-deficiency diabetes mellitus |
Non-Patent Citations (2)
| Title |
|---|
| 丁一等: "交泰丸在糖尿病治疗中的应用", 《临床医药文献杂志》 * |
| 万春燕: "抗氧化剂对2型糖尿病治疗作用的研究", 《中国优秀博硕士学位论文全文数据库（硕士） 医药卫生科技辑》 * |
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Application publication date: 20210108 |
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