CN112190612A - 一种适用于筋骨疾病治疗的膏药 - Google Patents
一种适用于筋骨疾病治疗的膏药 Download PDFInfo
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Abstract
本发明公开了一种适用于筋骨疾病治疗的膏药，以质量份计，该膏药包括以下组分：制川乌0.1‑6份、制草乌0.1‑9份、细辛0.1‑3份、乳香0.3‑10份、没药0.3‑10份、伸筋草0.5‑15份、透骨草0.5‑15份、全当归0.5‑15份、红花0.01‑12份、元胡索0.3‑12份、冬青油0.1‑15份、冰片0.015‑0.5份、煅白矾0.1‑6份。本发明舒筋健骨，活血止痛，治疗过程简单，无毒副作用，见效快，疼痛康复快，治愈率高，临床疗效远超同类产品。原材料成本较低，有效降低了病患的经济负担。
Description
技术领域
本发明涉及中药领域，尤其涉及一种适用于筋骨疾病治疗的膏药。
背景技术
人体是一个统一的整体，正常的生命活动有赖于气血、筋骨、脏腑、经络等各部分之间的功能正常，若机体遭受损伤后，脏腑、气血、筋骨、经络之间的功能必然产生紊乱或失调，导致一系列病变。“肢体损于外，则气血伤于内，营卫有所不贯，脏腑由之不和”，局部、外在的损伤可以导致整体的、内在的功能失调。跌打损伤、慢性劳损必伤及人体气血，气血不和，经络不通，气机不畅，血运闭阻，瘀血内停，气滞而血瘀。瘀则不通，不通则痛，血为有形，形伤则肿；气滞血瘀日久，瘀血过多，气血虚弱，筋骨失去濡养，筋挛骨痿，关节活动不灵或关节增生变形等。全身或局部气滞血瘀、营卫不和，腠理空疏，易受外邪侵入。寒邪侵袭，阻于经络，客于筋骨，留于肌肉，使气血失于鼓动，血涩不畅。寒为阴邪，易伤阳气，阳气受伤，筋脉失去温煦而挛缩收引，导致机体疼痛、肿胀、屈伸不利、功能活动受限等。疼痛、肿胀是筋肉与骨疾病伤及气血、经络两种重要病机的表现。治当活血行气、温通经络、消肿止痛，使气机通畅，血脉流通，筋骨得以濡养，疼痛、肿胀也就随之消失。
目前，医学上用于舒筋健骨、活血止痛的外用药物琳琅满目，让患者难以选择，同时这些药物的效果都不是很理想，所以需要开发一些疗效好，能有效帮助患者的外用药物成为人们研究的重点。因此，需要设计一种适用于筋骨疾病治疗的膏药。
发明内容
为了克服现有技术中的缺陷，提供一种适用于筋骨疾病治疗的膏药。
本发明通过下述方案实现：
一种适用于筋骨疾病治疗的膏药，以质量份计，该膏药包括以下组分：制川乌0.1-6份、制草乌0.1-9份、细辛0.1-3份、乳香0.3-10份、没药0.3-10份、伸筋草0.5-15份、透骨草0.5-15份、全当归0.5-15份、红花0.01-12份、元胡索0.3-12份、冬青油0.1-15份、冰片0.015-0.5份、煅白矾0.1-6份。
以质量份计，该膏药包括以下组分：制川乌3份、制草乌5份、细辛2份、乳香6份、没药5份、伸筋草8份、透骨草8份、全当归8份、红花6份、元胡索6份、冬青油9份、冰片0.3份、煅白矾3份。
本发明的有益效果为：
本发明提供一种适用于筋骨疾病治疗的膏药适用于颈肩痛、颈椎病、肩周炎、腰椎间突出、骨质增生、关节炎、跌打损伤、腱鞘炎、滑膜炎、腰肌劳损、痛风、风湿类风湿，腰腿痛，坐骨神经痛，酸麻肿胀，肌肉拉伤，股骨头坏死，痛经等治疗，舒筋健骨，活血止痛，治疗过程简单，无毒副作用，见效快，疼痛康复快，治愈率高，临床疗效远超同类产品。原材料成本较低，有效降低了病患的经济负担。
具体实施方式
下面结合具体实施例对本发明进一步说明：
一种适用于筋骨疾病治疗的膏药，以质量份计，该膏药包括以下组分：制川乌0.1-6份、制草乌0.1-9份、细辛0.1-3份、乳香0.3-10份、没药0.3-10份、伸筋草0.5-15份、透骨草0.5-15份、全当归0.5-15份、红花0.01-12份、元胡索0.3-12份、冬青油0.1-15份、冰片0.015-0.5份、煅白矾0.1-6份。
本申请诸味药材的功效如下所示，制川乌功效：温经通络、活血化瘀、祛风除湿、麻醉止痛、调血糖，强心。制草乌功效：祛风除湿，温经止痛。细辛：祛风散寒，通窍止血，温肺化饮。乳香功效：活血行气止痛，消肿生肌。没药功效：祛瘀消肿止痛。伸筋草：用量：0.5-15克，功效：祛风除湿，舒筋活血，解毒。透骨草功效：祛风除湿，舒筋活血。全当归功效：补血活血，调经止痛。红花功效：活血通经，散瘀止痛。元胡索功效：活血化瘀，行气止痛。冬青油：用量：0.1-15毫升，功效：活血止痛，杀虫。冰片功效：通诸窍，散郁火，去翳明目，消肿止痛。煅白矾功效：祛瘀燥湿，解毒杀虫，止血止泻。
下面结合具体实施例对本申请做进一步阐述。
实施例1
一种适用于筋骨疾病治疗的膏药，以质量份计，该膏药包括以下组分：制川乌6份、制草乌0.1份、细辛3份、乳香0.3份、没药10份、伸筋草0.5份、透骨草15份、全当归0.5份、红花12份、元胡索0.3份、冬青油15份、冰片0.015份、煅白矾6份。
实施例2
一种适用于筋骨疾病治疗的膏药，以质量份计，该膏药包括以下组分：制川乌0.1份、制草乌9份、细辛0.1份、乳香10份、没药0.3份、伸筋草15份、透骨草0.5份、全当归15份、红花0.01份、元胡索12份、冬青油0.1份、冰片0.5份、煅白矾0.1份。
实施例3
以质量份计，该膏药包括以下组分：制川乌3份、制草乌5份、细辛2份、乳香6份、没药5份、伸筋草8份、透骨草8份、全当归8份、红花6份、元胡索6份、冬青油9份、冰片0.3份、煅白矾3份。
本申请膏药的制备方法方法为：
第一步、按照配方将制川乌、制草乌、细辛、乳香、没药、伸筋草、透骨草、全当归、红花、元胡索、诸味中药分别打粉过120目筛，混匀后即为所需药粉；
第二步、将药粉消毒干燥后待用；
第三步、将冰片、煅白矾加入已经消毒灭菌的配药桶中，然后在加热搅拌过程中加入适量的冬青油，待冰片、煅白矾、冬青油至熔融状态后加入第二步消毒干燥后的药粉，搅拌均匀后得到药膏，将药膏涂于医用贴胶上，所得即为膏药成品。
本申请膏药的使用方法为：将胶面贴于患处，每天使用1-6片，每片单次使用小于24小时，再贴于患处。
对本申请的膏药成品进行毒性实验，结果如下所示：
一、急性毒性实验
完整皮肤准备：将大鼠在给药前24小时将背部脊柱两侧的毛剃掉。去毛面积约4cm×6cm2。破损皮肤准备：方法与完整皮肤准备相同，脱毛24小时后消毒，用针头在皮肤上划痕，以刺伤表皮，不伤真皮，轻度渗血为度。
将大鼠分为空白对照组和实验组，实验组又分为完整皮肤组和破损皮肤组，各3个剂量组，每组4只，雌雄各半。将本申请膏药均匀地涂敷于动物背部脱毛区24小时，24小时后，洗去受试的膏药，连续观察7天。7天内24只小鼠无一只死亡及明显中毒反应。
二、皮肤过敏性实验
取大鼠18只，随机分为3组，即空白基质组；高剂量膏药组；1％2，4一二硝基氯苯组；每组雌雄各半。按30mg/kg腹腔注射1％戊苯巴比妥钠麻醉，于给受试物前24h将大鼠背部两侧毛剃掉，去毛区范围每侧约4cm×6cm2，空白基质膏lg/只，高剂量组膏药lg/只，及1％2，4一二硝基氯苯0.2ml/只给药，涂于各组动物左侧脱毛区，持续6h，于第7、14天各重复l次，第28天用同样方法将本申请膏药和1％2，4一二硝基氯苯涂于右侧脱毛区，激发6h后除去受试物。观察24、48、72h皮肤过敏情况。无皮肤过敏反应。
三、皮肤刺激性实验
取大鼠12只，随机分为2组，即完整皮肤组；破损皮肤组；每组雌雄各半。按30mg/kg腹腔注射1％戊苯巴比妥钠麻醉，将高剂量的本申请膏药于各组大鼠背部左侧脱毛区涂敷，各鼠背部右侧脱毛区涂敷同面积的空自基质膏，24h给药一次，连续7天，除去大鼠背部残留的膏体，各组动物饮食、活动正常，无烦躁等异常精神状态及全身中毒症状。
本发明申请的膏药临床疗效分析如下所述：
本发明申请的膏药成品在西北某中医院已行临床应用近两年，该院骨伤科门诊与住院部536例患者，利用本发明上述实施例3的配方治疗的临床疗效总结报告如下：
一、基本情况
性别、年龄：男278例，女258例，年龄23-71，平均年龄46。
治疗病症：颈椎病、肩周炎、腰椎间突出、骨质增生、关节炎、腱鞘炎、滑膜炎。
二、治疗方法
1、(1)轻者每天抹一致三次，七天到半个月痊愈。无反弹无复发。
(2)长期慢性疾病，直接涂擦疼痛部位，抹第一次干后，一至两分钟后，抹第二次，这样疗效会更好。每天抹五至六次，一至三个月。
(3)严重的骨病患者只能起缓解作用，如“骨头坏死、骨刺、腰间盘突出、软骨坏死、腿已变形、胳膊手已变形”。
2、急性损伤，可以每隔两小时抹一次。
三、疗效评定
痊愈：自觉症状和体征消失，活动自如，恢复健康。
显效：症状和体征明显减轻，病情好转，不影响日常生活和工作。
有效：症状和体征有好转，病情好转，生活和工作不受影响。
无效：症状和体征无变化。
四、治疗效果
1、临床总体疗效
536例病人中，显效最快的病人在用药后5-10分钟即感疼痛减轻，可随意活动受限部位，部分病人用药1-2次即获痊愈。536例病人中，痊愈477例，显效35例，有效20例，无效4例，总有效率99、25％。
2、分病症疗效见表1
表1分病症疗效
与同类产品相比，本发明申请的膏药具有以下优点：
(1)疗程短，一般轻症，涂覆几次或几天就能治愈，疗效好。
(2)外用涂覆，对皮肤无刺激、无损害，没有其他的副作用，使用方便。
(3)祛痛快，一般涂覆后5—10分钟左右即可减轻或解除痛症。
(4)具有舒筋健骨，活血止痛的治本功效。
上述临床疗效分析和毒性实验中所用的膏药，均为按照本发明的中药制剂配方制备的膏药成品。
尽管已经对本发明的技术方案做了较为详细的阐述和列举，应当理解，对于本领域技术人员来说，对上述实施例做出修改或者采用等同的替代方案，这对本领域的技术人员而言是显而易见，在不偏离本发明精神的基础上所做的这些修改或改进，均属于本发明要求保护的范围。
Claims (2)
1.一种适用于筋骨疾病治疗的膏药，其特征在于，以质量份计，该膏药包括以下组分：制川乌0.1-6份、制草乌0.1-9份、细辛0.1-3份、乳香0.3-10份、没药0.3-10份、伸筋草0.5-15份、透骨草0.5-15份、全当归0.5-15份、红花0.01-12份、元胡索0.3-12份、冬青油0.1-15份、冰片0.015-0.5份、煅白矾0.1-6份。
2.根据权利要求1所述的一种适用于筋骨疾病治疗的膏药，其特征在于，以质量份计，该膏药包括以下组分：制川乌3份、制草乌5份、细辛2份、乳香6份、没药5份、伸筋草8份、透骨草8份、全当归8份、红花6份、元胡索6份、冬青油9份、冰片0.3份、煅白矾3份。
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| CN116850253A (zh) * | 2023-07-24 | 2023-10-10 | 山西圣康生物科技有限公司 | 一种治疗急性痛风纯中药喷雾剂 |
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| CN116139221A (zh) * | 2023-02-08 | 2023-05-23 | 张小奴 | 大马蜂多功能喷剂 |
| CN116850253A (zh) * | 2023-07-24 | 2023-10-10 | 山西圣康生物科技有限公司 | 一种治疗急性痛风纯中药喷雾剂 |
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